Redox chemistry at the platelet surface

Highly elastomeric poly(3-hydroxyoctanoate) based natural polymer composite for enhanced keratinocyte regeneration
Rai, R., Roether, J.A., Knowles, J.C., Mordan, N., Salih, V., Locke, I.C., Gordge, M.P., McCormick, A., Mohn, D., Stark, W.J., Keshavarz, T., Boccaccini, A.R. and Roy, I. 2017. Highly elastomeric poly(3-hydroxyoctanoate) based natural polymer composite for enhanced keratinocyte regeneration. International Journal of Polymeric Materials and Polymeric Biomaterials . 66 (7), pp. 326-335. https://doi.org/10.1080/00914037.2016.1217530

An investigation of the protective effect of alpha+-thalassaemia against severe Plasmodium falciparum amongst children in Kumasi, Ghana
Opoku-Okrah, C., Gordge, M.P., Kweku Nakua, E., Abgenyega, T., Parry, M., Robertson, C.E. and Smith, C.L. 2014. An investigation of the protective effect of alpha+-thalassaemia against severe Plasmodium falciparum amongst children in Kumasi, Ghana. International Journal of Laboratory Haematology. 36 (1), pp. 62-70. https://doi.org/10.1111/ijlh.12122

Alpha thalassaemia and the severity of Plasmodium falciparum infection in microcytic children from the Ashanti region of Ghana
Opoku-Okrah, C., Smith, C.L., Gordge, M.P., Parry, M., Robertson, C.E., Abgenyega, T. and Nakua, E. 2012. Alpha thalassaemia and the severity of Plasmodium falciparum infection in microcytic children from the Ashanti region of Ghana. British Society for Haematology 52nd meeting. Glasgow 16-18 April 2012

Cell surface thiol isomerases may explain the platelet-selective action of S-nitrosoglutathione
Xiao, F. and Gordge, M.P. 2011. Cell surface thiol isomerases may explain the platelet-selective action of S-nitrosoglutathione. Nitric Oxide: Biology and Chemistry. 25 (3), pp. 303-308. https://doi.org/10.1016/j.niox.2011.05.008

Nitric oxide: a one trick pony?
Gordge, M.P. 2010. Nitric oxide: a one trick pony? Journal of Thrombosis and Haemostasis. 8 (6), pp. 1340-1342. https://doi.org/10.1111/j.1538-7836.2010.03814.x

S-nitrosothiols as selective antithrombotic agents - possible mechanisms
Gordge, M.P. and Xiao, F. 2010. S-nitrosothiols as selective antithrombotic agents - possible mechanisms. British Journal of Pharmacology. 159 (8), pp. 1572-1580. https://doi.org/10.1111/j.1476-5381.2010.00670.x

Fabrication of a novel poly(3-hydroxyoctanoate) / nanoscale bioactive glass composite film with potential as a multifunctional wound dressing
Rai, R., Boccaccini, A.R., Knowles, J.C., Locke, I.C., Gordge, M.P., McCormick, A., Salih, V., Mordon, N., Keshavarz, T. and Roy, I. 2010. Fabrication of a novel poly(3-hydroxyoctanoate) / nanoscale bioactive glass composite film with potential as a multifunctional wound dressing. 5th international conference on times of polymers (TOP) and composites. Ischia, Italy 20–23 June 2010 https://doi.org/10.1063/1.3455552

Protein disulfide-isomerase mediates delivery of nitric oxide redox derivatives into platelets
Bell, S.E., Shah, C.M. and Gordge, M.P. 2007. Protein disulfide-isomerase mediates delivery of nitric oxide redox derivatives into platelets. Biochemical Journal. 403 (2), pp. 283-288. https://doi.org/10.1042/BJ20061146

Interactions between cell surface protein disulphide isomerase and S-nitrosoglutathione during nitric oxide delivery
Shah, C.M., Bell, S.E., Locke, I.C., Chowdrey, H.S. and Gordge, M.P. 2007. Interactions between cell surface protein disulphide isomerase and S-nitrosoglutathione during nitric oxide delivery. Nitric Oxide. 16 (1), pp. 135-142. https://doi.org/10.1016/j.niox.2006.08.001

Megakaryocyte apoptosis: sorting out the signals
Gordge, M.P. 2005. Megakaryocyte apoptosis: sorting out the signals. British Journal of Pharmacology. 145 (3), pp. 271-273. https://doi.org/10.1038/sj.bjp.0706202

Interactions between cell surface protein disulphide isomerase and S-nitrosoglutathione during nitric oxide delivery into MEG-01 megakaryocytes
Shah, C.M., Walters, S.E., Locke, I.C., Chowdrey, H.S. and Gordge, M.P. 2005. Interactions between cell surface protein disulphide isomerase and S-nitrosoglutathione during nitric oxide delivery into MEG-01 megakaryocytes. Ireland-UK Platelet Conference 2005. Dublin, Ireland 04-06 Sep 2005

Cell surface thiol modification by GSNO: a mechanism of nitric oxide delivery?
Shah, C.M., Locke, I.C., Chowdrey, H.S. and Gordge, M.P. 2004. Cell surface thiol modification by GSNO: a mechanism of nitric oxide delivery? 5th UK Nitric Oxide Forum. Edinburgh, UK 12/2004

Protein disulphide isomerase is involved in the delivery of NO from S-nitrosoglutathione into megakaryocytes
Shah, C.M., Locke, I.C., Chowdrey, H.S. and Gordge, M.P. 2004. Protein disulphide isomerase is involved in the delivery of NO from S-nitrosoglutathione into megakaryocytes. 3rd International Conference on the Biology, Chemistry and Therapeutic Applications of Nitric Oxide: 4th Anuual Scientific Meeting of the Nitric Oxide Society of Japan. Nara, Japan 24-28 May 2004 https://doi.org/10.1016/j.niox.2004.07.004

Protein disulphide isomerase is involved in the delivery of NO from S-nitrosoglutathione into megakaryocytes
Shah, C.M., Locke, I.C., Chowdrey, H.S. and Gordge, M.P. 2004. Protein disulphide isomerase is involved in the delivery of NO from S-nitrosoglutathione into megakaryocytes. Japan-UK Platelet Conference. Oxford, UK September 2004

Rapid S-nitrosothiol metabolism by platelets and megakaryocytes
Shah, C.M., Locke, I.C., Chowdrey, H.S. and Gordge, M.P. 2003. Rapid S-nitrosothiol metabolism by platelets and megakaryocytes. Biochemical Society Transactions. 31 (6), pp. 1450-1452.

Role of protein disulphide isomerase in NO delivery from S-nitrosothiols into megakaryocytes
Shah, C.M., Locke, I.C., Chowdrey, H.S. and Gordge, M.P. 2003. Role of protein disulphide isomerase in NO delivery from S-nitrosothiols into megakaryocytes. 4th UK Nitric Oxide Forum. University of Nottingham, UK December 2003

Mitochondrial superoxide production during oxalate-mediated oxidative stress in renal epithelial cells
Khand, F.D., Gordge, M.P., Robertson, W.G., Noronha-Dutra, A. and Hothersall, J. 2002. Mitochondrial superoxide production during oxalate-mediated oxidative stress in renal epithelial cells. Free Radical Biology & Medicine. 32 (12), pp. 1339-1350. https://doi.org/10.1016/S0891-5849(02)00846-8

Uremic concentrations of guanidino compounds inhibit neutrophil superoxide production
Hirayama, A., Noronha-Dutra, A., Gordge, M.P., Neild, G. and Hothersall, J. 2001. Uremic concentrations of guanidino compounds inhibit neutrophil superoxide production. Kidney International. 59 (suppl. 78), pp. 89-92. https://doi.org/10.1046/j.1523-1755.2001.59780089.x