Chickens’ Cry2: molecular analysis of an avian cryptochrome in retinal and pineal photoreceptors

Bailey, M.J., Chong, Nelson W., Xiong, J. and Cassone, V.M. 2002. Chickens’ Cry2: molecular analysis of an avian cryptochrome in retinal and pineal photoreceptors. FEBS Letters. 513 (2-3), pp. 169-174. https://doi.org/10.1016/S0014-5793(02)02276-7

TitleChickens’ Cry2: molecular analysis of an avian cryptochrome in retinal and pineal photoreceptors
AuthorsBailey, M.J., Chong, Nelson W., Xiong, J. and Cassone, V.M.
Abstract

We have identified and characterized an ortholog of the putative mammalian clock gene cryptochrome 2 (Cry2) in the chicken, Gallus domesticus. Northern blot analysis of gCry2 mRNA indicates widespread distribution in central nervous and peripheral tissues, with very high expression in pineal and retina. In situ hybridization of chick brain and retina reveals expression in photoreceptors and in visual and circadian system structures. Expression is rhythmic; mRNA levels predominate in late subjective night. The present data suggests that gCry2 is a candidate avian clock gene and/or photopigment and set the stage for functional studies of gCry2.

JournalFEBS Letters
Journal citation513 (2-3), pp. 169-174
ISSN0014-5793
YearFeb 2002
PublisherElsevier
Digital Object Identifier (DOI)https://doi.org/10.1016/S0014-5793(02)02276-7
Publication dates
PublishedFeb 2002

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