Testosterone and mood dysfunction in women with polycystic ovarian syndrome compared to subfertile controls

Barry, J.A., Hardiman, P.J., Saxby, B.K. and Kuczmierczyk, A.R. 2011. Testosterone and mood dysfunction in women with polycystic ovarian syndrome compared to subfertile controls. Journal of Psychosomatic Obstetrics and Gynecology. 32 (2), pp. 104-111.

TitleTestosterone and mood dysfunction in women with polycystic ovarian syndrome compared to subfertile controls
AuthorsBarry, J.A., Hardiman, P.J., Saxby, B.K. and Kuczmierczyk, A.R.
Abstract

Women with polycystic ovarian syndrome (PCOS) have been found to suffer from fertility problems and mood dysfunction. To control for any effect of fertility problems, the present study compared mood dysfunction in women with PCOS to non-PCOS women with fertility problems. Seventy-six women with PCOS and 49 subfertile controls reported their anxiety, depression and aggression levels, and the relationship between mood and testosterone (T) was assessed. Controlling for age and BMI using MANCOVA, women with PCOS were significantly more neurotic (had difficulty coping with stress) than controls, had more anger symptoms, were significantly more likely to withhold feelings of anger and had more quality of life problems related to the symptoms of their condition (acne, hirsutism, menstrual problems and emotions). In a subgroup of 30 women matched on age, BMI and ethnicity, it was found that women with PCOS were significantly more anxious and depressed than controls. T was not generally correlated with mood states. This is the first study to identify problems with neuroticism and withholding anger in women with PCOS. These mood problems appear to be mainly attributable to PCOS symptoms, though other factors, such as hypoglycaemia, cannot be ruled out.

JournalJournal of Psychosomatic Obstetrics and Gynecology
Journal citation32 (2), pp. 104-111
ISSN0167-482X
YearJun 2011
PublisherInforma Healthcare
Digital Object Identifier (DOI)doi:10.3109/0167482X.2011.568129
Publication dates
PublishedJun 2011

Related outputs

Anxiety and depression in polycystic ovary syndrome: a systematic review and meta-analysis
Barry, J.A., Kuczmierczyk, A.R. and Hardiman, P.J. 2011. Anxiety and depression in polycystic ovary syndrome: a systematic review and meta-analysis. Human Reproduction. 26 (9), pp. 2442-2451.

Age and sex differences in complications and convalescence after laparoscopic cholecystectomy
Siddiqui, M.R., Barry, J.A., Lodha, K., Parker, M. and Hasan, F.A. 2011. Age and sex differences in complications and convalescence after laparoscopic cholecystectomy. Magyar Seb├ęszet (Hungarian Journal of Surgery). 64 (4), pp. 193-201.

The impact of eating behavior on psychological symptoms typical of reactive hypoglycemia. A pilot study comparing women with polycystic ovary syndrome to controls
Barry, J.A., Bouloux, P. and Hardiman, P.J. 2011. The impact of eating behavior on psychological symptoms typical of reactive hypoglycemia. A pilot study comparing women with polycystic ovary syndrome to controls. Appetite. 57 (1), pp. 73-76.

Symmetric dimethylarginine (SDMA) is raised in women with polycystic ovary syndrome: a pilot study
Lakhani, K., Kay, A.R., Leiper, J., Barry, J.A. and Hardiman, P.J. 2011. Symmetric dimethylarginine (SDMA) is raised in women with polycystic ovary syndrome: a pilot study. Journal of Obstetrics and Gynaecology. 31 (5), pp. 417-419.

Measurement issues when assessing quality of life outcomes for different types of hernia mesh repair
Zaborszky, A., Gyanti, R., Barry, J.A., Saxby, B.K., Bhattacharya, P. and Hasan, F.A. 2011. Measurement issues when assessing quality of life outcomes for different types of hernia mesh repair. Annals of the Royal College of Surgeons of England. 93 (4), pp. 281-285.

Meta-analysis of sex difference in testosterone levels in umbilical cord blood
Barry, J.A., Hardiman, P.J., Siddiqui, M.R. and Thomas, M. 2011. Meta-analysis of sex difference in testosterone levels in umbilical cord blood. Journal of Obstetrics and Gynaecology. 31 (8), pp. 697-702.

Umbilical vein testosterone in female infants born to mothers with polycystic ovary syndrome is elevated to male levels
Barry, J.A., Kay, A.R., Navaratnarajah, R., Iqbal, S., Bamfo, J.E.A.K. and David, A.L. 2010. Umbilical vein testosterone in female infants born to mothers with polycystic ovary syndrome is elevated to male levels. Journal of Obstetrics and Gynaecology. 30 (5), pp. 444-446.

Permalink - https://westminsterresearch.westminster.ac.uk/item/8zv60/testosterone-and-mood-dysfunction-in-women-with-polycystic-ovarian-syndrome-compared-to-subfertile-controls


Share this
Tweet
Email