Lactose malabsorption and nutrition

Gerbault, P., Liebert, A., Swallow, D.M. and Thomas, M.G. 2014. Lactose malabsorption and nutrition. in: Lomer, M. (ed.) Advanced Nutrition and Dietetics in Gastroenterology Wiley. pp. 202-209

Chapter titleLactose malabsorption and nutrition
AuthorsGerbault, P., Liebert, A., Swallow, D.M. and Thomas, M.G.
EditorsLomer, M.
Abstract

Lactose needs to be digested by the small intestinal enzyme lactase into its constituent monosaccharides, glucose and galactose, before transport across the epithelial cell membranes. Lactase activity is therefore essential for the development of young mammals, since their sole source of nourishment is their mother's milk. This chapter summarizes what is known about the genetics and evolution of the lactase persistence (LP) trait. Symptoms of lactose intolerance can arise after an individual with hypolactasia has ingested lactose. Many dairy products contain only small amounts of lactose, allowing their consumption by most lactase non-persistent individuals. Bacteria and yeast fermentation convert the lactose in milk into various by-products, reducing the content of lactose. Nutritional epidemiology studies, and the staggering selective advantages that have favoured LP-associated alleles over the last 10,000 years, clearly show that adult milk consumption can be highly beneficial.

Book titleAdvanced Nutrition and Dietetics in Gastroenterology
Page range202-209
Year2014
PublisherWiley
Publication dates
Published2014
ISBN9780470671320
Digital Object Identifier (DOI)doi:10.1002/9781118872796.ch3.15

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