Vitamin B12 deficiency induces adipocyte dysfunction via enhanced cholesterol biosynthesis, unfolded protein response and associated epigenetic marks

Identification of the splice variants of Recepteur d'Origine nantais (RON) in lung cancer cell lines
Krishnaswamy, S., Bukhari, I., Mohammed, A.K., Amer, O.E., Tripathi, G., Alokail, M.S. and Al-Daghri, N.M. 2018. Identification of the splice variants of Recepteur d'Origine nantais (RON) in lung cancer cell lines. Gene. 679, pp. 335-340. https://doi.org/10.1016/j.gene.2018.09.027

Telmisartan reverses antiretroviral-induced adipocyte toxicity and insulin resistance in vitro
Pushpakom, S.P., Adaikalakoteswari, A., Owen, A., Back, D.J., Tripathi, G., Kumar, S., McTernan, P. and Pirmohamed, M. 2018. Telmisartan reverses antiretroviral-induced adipocyte toxicity and insulin resistance in vitro. Diabetes and Vascular Disease Research. 15 (3), pp. 233-242. https://doi.org/10.1177/1479164118757924

Differential expression of Lp-PLA2 in obesity and type 2 diabetes and the influence of lipids
Jackisch, L., Kumsaiyai, W., Moore, J.D., Al-Daghri, N., Kyrou, I., Barber, T.M., Randeva, H., Kumar, S., Tripathi, G. and McTernan, P.G. 2018. Differential expression of Lp-PLA2 in obesity and type 2 diabetes and the influence of lipids. Diabetologia. 61 (5), pp. 1155-1166. https://doi.org/10.1007/s00125-018-4558-6

Splice variants of the extracellular region of RON receptor tyrosine kinase in lung cancer cell lines identified by PCR and sequencing
Krishnaswamy, S., Mohammed, A.K., Tripathi, G., Alokail, M.S. and Al-Daghri, N.M. 2017. Splice variants of the extracellular region of RON receptor tyrosine kinase in lung cancer cell lines identified by PCR and sequencing. BMC Cancer. 17 (1), p. 738 738. https://doi.org/10.1186/s12885-017-3747-x

Vitamin D Receptor Gene Polymorphisms Modify Cardiometabolic Response to Vitamin D Supplementation in T2DM Patients
Al-Daghri, N.M., Mohammed, A.K., Al-Attas, O.S., Ansari, M.G.A., Wani, K., Hussain, S.D., Sabico, S., Tripathi, G. and Alokail, M.S. 2017. Vitamin D Receptor Gene Polymorphisms Modify Cardiometabolic Response to Vitamin D Supplementation in T2DM Patients. Scientific Reports. 7, p. 8280 8280. https://doi.org/10.1038/s41598-017-08621-7

Impact of gut hormone FGF-19 on type-2 diabetes and mitochondrial recovery in a prospective study of obese diabetic women undergoing bariatric surgery
Martinez de la Escalera, L., Kyrou, I., Vrbikova, J., Hainer, V., Sramkova, P., Fried, M., Piya, M.K., Kumar, S., Tripathi, G. and McTernan, P.G. 2017. Impact of gut hormone FGF-19 on type-2 diabetes and mitochondrial recovery in a prospective study of obese diabetic women undergoing bariatric surgery. BMC Medicine. 15 (1), p. 34 34. https://doi.org/10.1186/s12916-017-0797-5

Vitamin B12 deficiency induces cholesterol biosynthesis by limiting S-adenosyl methionine and altering the methylation of Srebf1 and Ldlr genes
Adaikalakoteswari, A., Finer, S., Voyias, P.D., McCarthy, C.M., Vatish, M., Moore, J., Smart-Halajko, M., Bawazeer, N., Al-Daghri, N.M., McTernan, P.G., Hitman, G.A., Saravanan, P. and Tripathi, G. 2016. Vitamin B12 deficiency induces cholesterol biosynthesis by limiting S-adenosyl methionine and altering the methylation of Srebf1 and Ldlr genes. Diabetes UK Professional Conference. London 11 - 13 Mar 2015 Wiley. https://doi.org/10.1111/dme.12668

Contribution of gut-derived bacterial LPS to mitochondrial dysfunction, oxidative stress and inflammation in human adipocytes
de la Escalera Clapp, L.M., Jackisch, L., Murphy, A., Piya, M.K., Kumar, S., Tripathi, G. and McTernan, P.G. 2016. Contribution of gut-derived bacterial LPS to mitochondrial dysfunction, oxidative stress and inflammation in human adipocytes. 7th World Congress on Targeting Mitochondria. Berlin, Germany 24 - 26 Oct 2016 World Mitochondria Society. https://doi.org/10.18143/JWMS_v2i2_1898

Superfood ‘Freeze Dried Broccoli Extract’ to the rescue of mitochondrial inefficiency in human mature adipocytes
Murphy, A., Tripathi, G., Barker, G., Chappell, M. and McTernan, P.G. 2016. Superfood ‘Freeze Dried Broccoli Extract’ to the rescue of mitochondrial inefficiency in human mature adipocytes. 7th World Congress on Targeting Mitochondria. Berlin, Germany 24 - 26 Oct 2016 World Mitochondria Society. https://doi.org/10.18143/JWMS_v2i2_1935

Freeze dried broccoli extract relieves ER stress and mitochondrial inefficiency in differentiated human pre-adipocyte cells
Murphy, A., Jackisch, L., Azharian, S., Aladel, A., Barker, G., Tripathi, G., Chappell, M. and McTernan, P. 2016. Freeze dried broccoli extract relieves ER stress and mitochondrial inefficiency in differentiated human pre-adipocyte cells. Society for Endocrinology BES 2016. Brighton 07 - 09 Nov 2016 Society for Endocrinology. https://doi.org/10.1530/endoabs.44.P191

Vitamin B12 deficiency impairs insulin signalling in human adipocytes by down regulating Akt via PTEN/Trb3
Adaikalakoteswari, A., Vatish, M., McTernan, P., Saravanan, P. and Tripathi, G. 2016. Vitamin B12 deficiency impairs insulin signalling in human adipocytes by down regulating Akt via PTEN/Trb3. Diabetes UK Professional Conference. Glasgow 02 - 04 Mar 2016 Wiley. https://doi.org/10.1111/dme.13048

ER stress mediates mitochondrial dysfunction in human adipocytes which is exacerbated in obesity
Jackisch, L., de la Escalera, L.M., Murphy, A., McTernan, P., Randeva, H. and Tripathi, G. 2016. ER stress mediates mitochondrial dysfunction in human adipocytes which is exacerbated in obesity. 7th World Congress on Targeting Mitochondria. Berlin, Germany 24 - 26 Oct 2016 World Mitochondria Society. https://doi.org/10.18143/JWMS_v2i2_1921

Tunicamycin-induced ER stress mediates mitochondrial dysfunction in human adipocytes
Jackisch, L., Murphy, A., Al-Daghri, N., McTernan, P., Randeva, H. and Tripathi, G. 2016. Tunicamycin-induced ER stress mediates mitochondrial dysfunction in human adipocytes. Society for Endocrinology BES 2016. Brighton 07 - 09 Nov 2016 Society for Endocrinology. https://doi.org/10.1530/endoabs.44.P193

Novel splicing variants of recepteur d'origine nantais (RON) tyrosine kinase involving exons 15–19 in lung cancer
Krishnaswamy, S., Mohammed, A.K., Amer, O.E., Tripathi, G., Alokail, M.S. and Al-Daghri, N.M. 2016. Novel splicing variants of recepteur d'origine nantais (RON) tyrosine kinase involving exons 15–19 in lung cancer. Lung Cancer. 92, pp. 41-46. https://doi.org/10.1016/j.lungcan.2015.12.002

Surface Charge Visualization at Viable Living Cells
Perry, D., Paulose Nadappuram, B., Momotenko, D., Voyias, P.D., Page, A., Tripathi, G., Frenguelli, B.G. and Unwin, P.R. 2016. Surface Charge Visualization at Viable Living Cells. Journal of the American Chemical Society. 138 (9), pp. 3152-3160. https://doi.org/10.1021/jacs.5b13153

Short-chain Fatty Acid Acetate Stimulates Adipogenesis and Mitochondrial Biogenesis via GPR43 in Brown Adipocytes
Hu, J., Kyrou, I., Tan B.K., Dimitriadis, G.K., Ramanjaneya, M., Tripathi, G., Patel, V., James, S., Kawan, M., Chen, J. and Randeva, H.S. 2016. Short-chain Fatty Acid Acetate Stimulates Adipogenesis and Mitochondrial Biogenesis via GPR43 in Brown Adipocytes. Endocrinology. 157 (5), pp. 1881-1894. https://doi.org/10.1210/en.2015-1944

Association of Vitamin B12 with Pro-Inflammatory Cytokines and Biochemical Markers Related to Cardiometabolic Risk in Saudi Subjects
Al-Daghri, N.M., Rahman, S., Sabico, S., Yakout, S., Wani, K., Al-Attas, O.S., Saravanan, P., Tripathi, G., McTernan, P.G. and Alokail, M.S. 2016. Association of Vitamin B12 with Pro-Inflammatory Cytokines and Biochemical Markers Related to Cardiometabolic Risk in Saudi Subjects. Nutrients. 8 (9) 460. https://doi.org/10.3390/nu8090460

PWE-254 Is the macroscopically normal mucosa (MNM) around colorectal cancer really ‘normal’?
Patel, A., Fang, Y., Moore, J., Williams, N., Tripathi, G. and Arasaradnam, R. 2015. PWE-254 Is the macroscopically normal mucosa (MNM) around colorectal cancer really ‘normal’? 2nd Digestive Disorders Federation Conference. London 22 - 25 Jun 2015 BMJ. https://doi.org/10.1136/gutjnl-2015-309861.700

Enhanced thermic effect of food, postprandial NEFA suppression and raised adiponectin in obese women who eat slowly
Reddy, N.L., Peng, C.J., Carreira, M.C., Halder, L., Hattersley, J., Piya, M.K., Tripathi, G., Randeva, H.S., Casanueva, F.F., McTernan, P.G., Kumar, S. and Barber, T.M. 2015. Enhanced thermic effect of food, postprandial NEFA suppression and raised adiponectin in obese women who eat slowly. Clinical Endocrinology. 82 (6), pp. 831-837. https://doi.org/10.1111/cen.12652

Field cancerisation in colorectal cancer: A new frontier or pastures past?
Patel, A., Tripathi, G., Gopalakrishnan, K., Williams, N. and Arasaradnam, R.P. 2015. Field cancerisation in colorectal cancer: A new frontier or pastures past? World Journal of Gastroenterology. 21 (13), pp. 3763-3762. https://doi.org/10.3748/wjg.v21.i13.3763

Low Maternal Vitamin B12 Status Is Associated with Lower Cord Blood HDL Cholesterol in White Caucasians Living in the UK
Adaikalakoteswari, A., Vatish, M., Lawson, A., Wood, C., Sivakumar, K., McTernan, P.G., Webster, C., Anderson, N., Yajnik, C.S., Tripathi, G. and Saravanan, P. 2015. Low Maternal Vitamin B12 Status Is Associated with Lower Cord Blood HDL Cholesterol in White Caucasians Living in the UK. Nutrients. 7 (4), pp. 2401-2414. https://doi.org/10.3390/nu7042401

Habitual Physical Activity is Associated with Circulating Irisin in Healthy Controls but not in Subjects with Diabetes Mellitus Type 2
Al-Daghri, N.M., Alokail, M.S., Rahman, S., Amer, O.E., Al-Attas, O.S., Alfawaz, H., Tripathi, G., Sabico, S., Chrousos, G.P., McTernan PG and Milan, P.K. 2015. Habitual Physical Activity is Associated with Circulating Irisin in Healthy Controls but not in Subjects with Diabetes Mellitus Type 2. European Journal of Clinical Investigation. 45 (8), pp. 775-781. https://doi.org/10.1111/eci.12468

Recepteur d'Origine nantais (RON) tyrosine kinase splicing variants lacking exons 18 and 19 occur ubiquitously in lung cancer
Krishnaswamy, S., Mohammed, A.K., Amer, O.E., Tripathi, G., Alokail, M.S. and Al-Daghri, N.M. 2015. Recepteur d'Origine nantais (RON) tyrosine kinase splicing variants lacking exons 18 and 19 occur ubiquitously in lung cancer. International Journal of Clinical and Experimental Medicine. 8 (11), pp. 20778-86.

Postprandial effect of a high-fat meal on endotoxemia in arab women with and without insulin-resistance-related diseases
Al-Disi, D.A., Al-Daghri, N.M., Khan, N., Alfadda, A.A., Sallam, R.M., Alsaif, M., Sabico, S., Tripathi, G. and McTernan, P.G. 2015. Postprandial effect of a high-fat meal on endotoxemia in arab women with and without insulin-resistance-related diseases. Nutrients. 7 (8), pp. 6375-6389. https://doi.org/10.3390/nu7085290

Vitamin B12 in sufficiency induces cholesterol biosynthesis by limiting s-adenosylmethionine and modulating the methylation of SREBF1 and LDLR genes
Adaikalakoteswari, A., Finer, S., Voyias, P.D., McCarthy, C.M., Vatish, M., Moore, J., Smart-Halajko, M.C., Bawazeer, N., Al-Daghri, N.M., McTernan, P.G., Kumar, S., Hitman, G.A., Saravanan, P. and Tripathi, G. 2015. Vitamin B12 in sufficiency induces cholesterol biosynthesis by limiting s-adenosylmethionine and modulating the methylation of SREBF1 and LDLR genes. Clinical Epigenetics. 7 (1), p. 14. https://doi.org/10.1186/s13148-015-0046-8

Unfolded protein response in adipose tissue of obese diabetic women significantly improved 6 months post bariatric surgery, irrespective of malabsorptive or bypass operation type and correlates with plasma glucose concentration
Voyias, P., Antonysunil, A., Kumasaiyai, W., Kyrou, I., Vrbikova, J., Hainer, V., Fried, M., Sramkova, P., Saravanan, P., Kumar, S., McTernan, P. and Tripathi, G. 2014. Unfolded protein response in adipose tissue of obese diabetic women significantly improved 6 months post bariatric surgery, irrespective of malabsorptive or bypass operation type and correlates with plasma glucose concentration. Society for Endocrinology BES 2014. Liverpool 24 - 27 May 2017 Society for Endocrinology. https://doi.org/10.1530/endoabs.34.P269

A 3-month low fat diet leads to significant lipid profile improvement in obese T2DM Saudi subjects, without substantial weight loss, and the capacity to manage a damaging high-fat meal challenge more appropriately post intervention
Al-Disi, D., Al-Daghri, N., Khan, N., Alsaif, M., Alfadda, A., Sabico, S., Tripathi, G. and McTernan, P. 2014. A 3-month low fat diet leads to significant lipid profile improvement in obese T2DM Saudi subjects, without substantial weight loss, and the capacity to manage a damaging high-fat meal challenge more appropriately post intervention. Society for Endocrinology BES 2014. Liverpool 24 - 27 May 2014 Society for Endocrinology. https://doi.org/10.1530/endoabs.34.P223

Systemic triglycerides as a key determinant of TLR regulated inflammatory risk in human adipose tissue post bariatric surgical intervention and weight loss
Kumsaiyai, W., Al-Daghri, N., Kyrou, I., Vrbikova, J., Hainer, V., Fried, M., Sramkova, P., Barber, T., S Kumar,, Tripathi, G. and McTernan, P. 2014. Systemic triglycerides as a key determinant of TLR regulated inflammatory risk in human adipose tissue post bariatric surgical intervention and weight loss. Society for Endocrinology BES 2014. Liverpool 24 - 27 Mar 2014 Society for Endocrinology. https://doi.org/10.1530/endoabs.34.P238

Meal size and frequency influences metabolic endotoxaemia and inflammatory risk but has no effect on diet induced thermogenesis in either lean or obese subjects
Piya, M., Reddy, N., Campbell, A., Hattersley, J., Halder, L., Tripathi, G., Tahrani, A., Kumar, S., Barber, T. and McTernan, P. 2014. Meal size and frequency influences metabolic endotoxaemia and inflammatory risk but has no effect on diet induced thermogenesis in either lean or obese subjects. Society for Endocrinology BES 2014. Liverpool 24 - 27 May 2014 Society for Endocrinology. https://doi.org/10.1530/endoabs.34.P226

Elevated cord leptin from low B12 mothers predicts birth weight
Antonysunil, A., Vatish, M., Lawson, A., Wood, C., Sivakumar, K., Webster, C., Anderson, N., McTernan, P., Tripathi, G. and Saravanan, P. 2014. Elevated cord leptin from low B12 mothers predicts birth weight. Society for Endocrinology BES 2014. Liverpool 24 - 27 May 2014 Society for Endocrinology. https://doi.org/10.1530/endoabs.34.P262

Bariatric surgery induced weight loss and systemic glucose regulates intracellular unfolded protein response within human adipose tissue from type 2 diabetes mellitus patients
Voyias, P., Antonysunil, A., Kumasaiyai, W., Kyrou, I., Vrbikova, J., Hainer, V., Fried, M., Sramkova, P., Saravanan, P., Kumar, S., McTernan, P. and Tripathi, G. 2014. Bariatric surgery induced weight loss and systemic glucose regulates intracellular unfolded protein response within human adipose tissue from type 2 diabetes mellitus patients. 74th Scientific Sessions of the American Diabetes Association. San Francisco, USA 13 - 17 Jun 2014

Methyl Donor Deficiency Due to Low Vitamin B12 Impairs Insulin Signalling in Human Adipocytes by Down Regulating Akt Pathway via PTEN and TRB3
Adaikalakoteswari, A., Finer, S., Voyias, P.D., McCarthy, M., Vatish, M., Moore, J., Smart-Halajko, M., Bawazeer, N., Al-Daghri, N.M., McTernan, P.G., Hitman, G.A., Saravanan, P. and Tripathi, G. 2014. Methyl Donor Deficiency Due to Low Vitamin B12 Impairs Insulin Signalling in Human Adipocytes by Down Regulating Akt Pathway via PTEN and TRB3. 74th Scientific Sessions of the American Diabetes Association. San Francisco, USA 13 - 17 Jun 2014

PWE-001 Field Cancerisation Theory In Colorectal Cancer (crc): What Role Do Fibroblast Growth Factors Have?
Patel, A., N Williams, N., Nwokolo, C., Tripathi, G. and Arasaradnam, R. 2014. PWE-001 Field Cancerisation Theory In Colorectal Cancer (crc): What Role Do Fibroblast Growth Factors Have? British Society of Gastroenterology Annual General Meeting. 16 - 19 Jun 2014 BMJ. https://doi.org/10.1136/gutjnl-2014-307263.261

Identification of Brown Adipose Tissue Using MR Imaging in a Human Adult With Histological and Immunohistochemical Confirmation
Reddy, N.L., Jones, T.A., Wayte, S.C., Adesanya, O., Sankar, S., Yeo, Y.C., Tripathi, G., McTernan, P.G., Randeva, H.S., Kumar, S., Hutchinson, C.E. and Barber, T.M. 2014. Identification of Brown Adipose Tissue Using MR Imaging in a Human Adult With Histological and Immunohistochemical Confirmation. The Journal of Clinical Endocrinology & Metabolism. 99 (1), pp. E117-E121. https://doi.org/10.1210/jc.2013-2036

Maternal inheritance of circulating irisin in humans
Al-Daghri, N.M., Al-Attas, O.S., Alokail, M.S., Alkharfy, K.M., Yousef, M., Vinodson, B., Amer, O.E., Alnaami, A.M., Sabico, S., Tripathi, G., Piya, M.K., McTernan, P.G. and Chrousos, G.P. 2014. Maternal inheritance of circulating irisin in humans. Clinical Science. 126 (12), pp. 837-844. https://doi.org/10.1042/CS20130426

Vitamin B12 deficiency is associated with adverse lipid profile in Europeans and Indians with type 2 diabetes
Adaikalakoteswari, A., Jayashri, R., Sukumar, N., Venkataraman, H., Pradeepa, R., Gokulakrishnan, K., Anjana, R., McTernan, P.G., Tripathi, G., Patel, V., Kumar, S,, Mohan, V. and Saravanan, P. 2014. Vitamin B12 deficiency is associated with adverse lipid profile in Europeans and Indians with type 2 diabetes. Cardiovascular Diabetology. 13 (1), p. 129. https://doi.org/10.1186/s12933-014-0129-4

The Identification of Irisin in Human Cerebrospinal Fluid: Influence of Adiposity, Metabolic Markers and Gestational Diabetes
Piya, M.K., Harte, A.L., Sivakumar, K., Tripathi, G., Voyias, P.D., James, S., Sabico, S., Al-Daghri, N.M., Saravanan, P., Barber, T.M., Kumar, S., Vatish, M. and McTernan, P.G. 2014. The Identification of Irisin in Human Cerebrospinal Fluid: Influence of Adiposity, Metabolic Markers and Gestational Diabetes. American Journal of Physiology - Endocrinology and Metabolism. 306 (5), pp. E512-E518. https://doi.org/10.1152/ajpendo.00308.2013

Identification of a novel heterozygous mutation in exon 50 of the COL1A1 gene manifesting clinically as osteogenesis imperfecta
Owen, N., Reddy, N., Aftab, S.A.S., Harte, A.L., McTernan, P.G., Tripathi, G. and Barber, T.M. 2013. Identification of a novel heterozygous mutation in exon 50 of the COL1A1 gene manifesting clinically as osteogenesis imperfecta. Society for Endocrinology BES 2013. Harrogate, UK 18 - 21 Mar 2013 BioScientifica Ltd.. https://doi.org/10.1530/endoabs.31.P13

Unfolded protein response pathway, IRE1α-XBP1 is altered during adipogenesis in obese human adipocytes
Voyias, P., McCarthy, C., Antonysunil, A., Kumsaiyai, W., Harte, A., McTernan, P. and Tripathi, G. 2013. Unfolded protein response pathway, IRE1α-XBP1 is altered during adipogenesis in obese human adipocytes. Society for Endocrinology BES 2013. Harrogate, UK 18 - 21 Mar 2013 BioScientifica Ltd.. https://doi.org/10.1530/endoabs.31.P201

Vitamin B12 and folate imbalance induces cholesterol synthesis and endoplasmic reticulum stress in human adipocytes
Adaikalakoteswari, A., Moore, J., Ciara, M., Voyais, P., Mcternan, P., Saravanan, P. and Tripathi, G. 2013. Vitamin B12 and folate imbalance induces cholesterol synthesis and endoplasmic reticulum stress in human adipocytes. Society for Endocrinology BES 2013. Harrogate, UK 18 - 21 Mar 2013 BioScientifica Ltd.. https://doi.org/10.1530/endoabs.31.P182

Altered mitochondrial dynamics in obesity: redressing the balance through bariatric surgery?
McCarthy, C., Voyias, P., Antonysunil, A., Harte, A., Saravanan, P., Kyrou, I., Tripathi, G. and McTernan, P.G. 2013. Altered mitochondrial dynamics in obesity: redressing the balance through bariatric surgery? Society for Endocrinology BES 2013. Harrogate, UK 18 - 21 Mar 2013 BioScientifica Ltd.. https://doi.org/10.1530/endoabs.31.P204

Eating more quickly heightens overall systemic exposure to glucose and NEFA in the post-prandial phase, irrespective of energy expenditure in obese women
Reddy, N., Peng, C., Piya, M.K., Aftab, S.A.S., Campbell, A., Hattersley, J., Halder, L., Harte, A.L., Randeva, H., Tripathi, G., McTernan, P.G., Kumar, S. and Barber, T.M. 2013. Eating more quickly heightens overall systemic exposure to glucose and NEFA in the post-prandial phase, irrespective of energy expenditure in obese women. Society for Endocrinology BES 2013. Harrogate, UK 18 - 21 Mar 2013 BioScientifica Ltd.. https://doi.org/10.1530/endoabs.31.P219

Maternal B12 insufficiency predicts neonate's metabolic risk factors
Adaikalakoteswari, A., Alexander, L., Webster, C., Wood, C., Anderson, N., Sivakumar, K., McTernan, P., Tripathi, G., Vatish, M. and Saravanan, P. 2013. Maternal B12 insufficiency predicts neonate's metabolic risk factors. Society for Endocrinology BES 2013. Harrogate, UK 18 - 21 Mar 2013 BioScientifica Ltd.. https://doi.org/10.1530/endoabs.31.P210

Human abdominal subcutaneous adipocytes as an active source of LpPLA2, influenced by fat depot and metabolic state, with LpPLA2 converting LDL into more potent atherogenic Ox-LDL, in vitro
Kumsaiyai, W., Harte, A., Al-Naji, F., Al-Daghri, N., Kyrou, I., Barber, T., Sabico, S., Tripathi, G. and McTernan, P.G. 2013. Human abdominal subcutaneous adipocytes as an active source of LpPLA2, influenced by fat depot and metabolic state, with LpPLA2 converting LDL into more potent atherogenic Ox-LDL, in vitro. Society for Endocrinology BES 2013. Harrogate, UK 18 - 21 Mar 2013 BioScientifica Ltd.. https://doi.org/10.1530/endoabs.31.P188

FGF21 action on human adipose tissue compromised by reduced βKlotho and FGFR1 expression in type 2 diabetes mellitus
Piya, M.K., Harte, A.L., Chittari, M.V., Tripathi, G., Kumar, S. and McTernan, P.G. 2013. FGF21 action on human adipose tissue compromised by reduced βKlotho and FGFR1 expression in type 2 diabetes mellitus. Society for Endocrinology BES 2013. Harrogate, UK 18 - 21 Mar 2013 BioScientifica Ltd.. https://doi.org/10.1530/endoabs.31.P179

Raised circulating fibroblast growth factor 21 (FGF21) coupled with reduced adipose tissue BetaKlotho and FGF21 receptor 1 (FGFR1) expression in Type 2 diabetes may in part explain FGF21 resistance
Piya, M.K., Harte, A.L., Kyrou, I., Chitari, M.V., Tripathi, G., Kumar, S. and McTernan, P.G. 2013. Raised circulating fibroblast growth factor 21 (FGF21) coupled with reduced adipose tissue BetaKlotho and FGF21 receptor 1 (FGFR1) expression in Type 2 diabetes may in part explain FGF21 resistance. Diabetes UK Professional Conference 2013. Manchester Central Convention Complex, Manchester, UK 13 - 15 Mar 2013 Wiley. https://doi.org/10.1111/dme.12090_2

The impact of high fat meal frequency on metabolic profile and energy expenditure in obese subjects
Piya, M.K., Reddy, N., Harte, A., Campbell, A., Hattersley, J., Halder, L., Tahran, A.A., Tripathi, G., Aftab, S.A.S., Barber, T.M., McTernan, P.G. and Kumar, S. 2013. The impact of high fat meal frequency on metabolic profile and energy expenditure in obese subjects. 49th Annual Meeting of the EASD. Barcelona, Spain 23 - 27 Sep 2013 Springer. https://doi.org/10.1007/s00125-013-3012-z

dentification of a novel heterozygous mutation in exon 50 of the COL1A1 gene causing osteogenesis imperfecta
Aftab, S.A.S., Reddy, N., Owen, N.L., Pollitt, R., Harte, A., McTernan, P.G., Tripathi, G. and Barber, T.M. 2013. dentification of a novel heterozygous mutation in exon 50 of the COL1A1 gene causing osteogenesis imperfecta. Endocrinology, Diabetes & Metabolism Case Reports. 7 (2013), p. EDM130002 EDM130002. https://doi.org/10.1530/EDM-13-0002

Raised circulating fibroblast growth factor 21 (FGF21) coupled with reduced adipose tissue BetaKlotho and FGF21 receptor 1 (FGFR1) expression in Type 2 diabetes may in part explain FGF21 resistance
Piya, M.K., Harte, A.L., Kyrou, I., Chitari, M.V., Tripathi, G., Kumar, S. and McTernan, P.G. 2013. Raised circulating fibroblast growth factor 21 (FGF21) coupled with reduced adipose tissue BetaKlotho and FGF21 receptor 1 (FGFR1) expression in Type 2 diabetes may in part explain FGF21 resistance. Diabetic Medicine. 30, pp. 3-.

NFκB as a potent regulator of inflammation in human adipose tissue, influenced by depot, adiposity, T2DM status, and TNFα
Harte, A.L., Tripathi, G., Piya, M.K., Barber, T.M., Clapham, J.C., Al-Daghri, N., Al-Disi, D., Kumsaiyai, W., Saravanan, P., Fowler, A.E., O'Hare, J.P., Kumar, S. and McTernan, P.G. 2013. NFκB as a potent regulator of inflammation in human adipose tissue, influenced by depot, adiposity, T2DM status, and TNFα. Obesity. 21 (11), pp. 2322-2330. https://doi.org/10.1002/oby.20336

Post-prandial high fat intake leads to acute exposure to circulating endotoxin in type 2 diabetes mellitus subjects
Harte, A., Varma, M., Tripathi, G., McGee, K., Al-Daghri, N., Al-Attas, O., Sabico, S., O'Hare, J., Ceriello, A., Saravanan, P., Kumar, S. and McTernan, P. 2012. Post-prandial high fat intake leads to acute exposure to circulating endotoxin in type 2 diabetes mellitus subjects. Society for Endocrinology BES 2012. Harrogate, UK 18 - 22 Mar 2012 BioScientifica Ltd..

The effects of bariatric surgery on the endoplasmic reticulum stress pathway in human adipose tissue
Voyias, P., McCarthy, C., Antonysunil, A., Kumasaiyai, W., Al Naji, F., McGee, K., Harte, A., Saravanan, P., Kyrou, I., McTernan, P. and Tripathi, G. 2012. The effects of bariatric surgery on the endoplasmic reticulum stress pathway in human adipose tissue. Society for Endocrinology BES 2012. Harrogate, UK 18 - 22 Mar 2012 BioScientifica Ltd..

The adipocyte as an active source of PLA2 isoforms influenced by adiposity, depot specificity and Type 2 Diabetes Mellitus
Kumsaiyai, W., Harte, A., Saravanan, P., Kyrou, I., Aldaghri, N., Al-Attas, O., Kumar, S., Tripathi, G. and McTernan, P. 2012. The adipocyte as an active source of PLA2 isoforms influenced by adiposity, depot specificity and Type 2 Diabetes Mellitus. Society for Endocrinology BES 2012. Harrogate, UK 18 - 22 Mar 2012 BioScientifica Ltd..

Expression of genes regulating mitochondrial fusion and fission in human adipose tissue are influenced by adiposity and bariatric surgery
McCarthy, C., Voyias, P., Antonysunil, A., McGee, K., Harte, A., Saravanan, P., Kyrou, I., Kumar, S., McTernan, P. and Tripathi, G. 2012. Expression of genes regulating mitochondrial fusion and fission in human adipose tissue are influenced by adiposity and bariatric surgery. Society for Endocrinology BES 2012. Harrogate, UK 18 - 22 Mar 2012 BioScientifica Ltd..

Chronic or intermittent exposure to Oleic acid (MUFA) induces a greater NFκB activated inflammatory response than Eicosapentaenoic acid (PUFA) in differentiated human adipocytes
Piya, M., Harte, A., McGee, K., Reddy, N., Tripathi, G., McTernan, P. and Kumar, S. 2012. Chronic or intermittent exposure to Oleic acid (MUFA) induces a greater NFκB activated inflammatory response than Eicosapentaenoic acid (PUFA) in differentiated human adipocytes. Society for Endocrinology BES 2012. Harrogate, UK 18 - 22 Mar 2012 BioScientifica Ltd..

Evidence for a shift to anaerobic metabolism in adipose tissue in efavirenz-containing regimens for HIV with different nucleoside backbones
McGee, K.C., Shahmanesh, M., Boothby, M., Nightingale, P., Gathercole, L.L., Tripathi, G., Harte, A.L., Shojaee-Moradie, F., Umpleby, A.M., Das, S., Al-Daghr, N.M., McTernan, P.G. and Tomlinson, J.W. 2012. Evidence for a shift to anaerobic metabolism in adipose tissue in efavirenz-containing regimens for HIV with different nucleoside backbones. Antiviral Therapy. 17 (3), pp. 495-507. https://doi.org/10.3851/IMP2017

Telomere Length Attrition, a Marker of Biological Senescence, Is Inversely Correlated with Triglycerides and Cholesterol in South Asian Males with Type 2 Diabetes Mellitus
Harte, A.L., da Silva, N.F., Miller, M.A., Cappuccio, F.P., Kelly, A., O'Hare, J.P., Barnett, A.H., Al-Daghri, N.M., Al-Attas, O., Alokail, M., Sabico, S., Tripathi, G., Bellary, S., Kumar, S. and McTernan, P.G. 2012. Telomere Length Attrition, a Marker of Biological Senescence, Is Inversely Correlated with Triglycerides and Cholesterol in South Asian Males with Type 2 Diabetes Mellitus. Experimental Diabetes Research. 2012 895185. https://doi.org/10.1155/2012/895185

High Fat Intake Leads to Acute Postprandial Exposure to Circulating Endotoxin in Type 2 Diabetic Subjects
Harte, A.L., Varma, M.C., Tripathi, G., McGee, K.M., Al-Daghri, N.M., Al-Attas, O.S., Sabico, S., O'Hare, J.P., Ceriello, A., Saravanan, P., Kumar, S. and McTernan, P.G. 2012. High Fat Intake Leads to Acute Postprandial Exposure to Circulating Endotoxin in Type 2 Diabetic Subjects. Diabetes Care. 35 (2), pp. 375-382. https://doi.org/10.2337/dc11-1593

GLP-1 analogue, Liraglutide protects human umbilical vein endothelial cells against high glucose induced endoplasmic reticulum stress
Schisano, D., Harte, A.L., Lois, K., Saravanan, P., Al-Daghri, N., Al-Attas, O., Knudsen, L.B., McTernan, P.G., Ceriello, A. and Tripathi, G. 2012. GLP-1 analogue, Liraglutide protects human umbilical vein endothelial cells against high glucose induced endoplasmic reticulum stress. Regulatory Peptides. 174 (1-3), pp. 46-52. https://doi.org/10.1016/j.regpep.2011.11.008

Does endotoxaemia contribute to osteoarthritis in obese patients?
Metcalfe, D., Harte, A.L., Aletrari, M.O., Al Daghri, N.M., Al Disi, D., Tripathi, G. and McTernan, P.G. 2012. Does endotoxaemia contribute to osteoarthritis in obese patients? Clinical Science. 123 (11), pp. 627-634. https://doi.org/10.1042/CS20120073

Low B12 and High Folate: Novel Mechanism of Higher Insulin Resistance in Human Adipocytes
Adaikalakoteswari, A., Tripathi, G. and Saravanan, P. 2011. Low B12 and High Folate: Novel Mechanism of Higher Insulin Resistance in Human Adipocytes. 7th World Congress on Developmental Origins of Health and Disease. Portland, Oregon, USA 18 - 21 Sep 2011 Cambridge University Press. https://doi.org/10.1017/S2040174411000481

Low B12 and high folate: a novel regulator of cholesterol biosynthesis in human adipocytes
Adaikalakoteswari, A., Moore, J., McTernan, P.G., Kumar, S., Saravanan, P. and Tripathi, G. 2011. Low B12 and high folate: a novel regulator of cholesterol biosynthesis in human adipocytes. 47th Annual Meeting of the EASD. Lisbon 12 - 16 Sep 2011 Springer. https://doi.org/10.1007/s00125-011-2276-4

Mitochondrial bioenergetics changes are induced by metabolic endotoxinaemia contributing to mitochondrial stress and dysfunction in human adipocytes
McGee, K.C., Harte, A.L., Oscarsson, J., Brown, A., Fernandes Da Silva, N., McCarthy, C., Clapham, J., Kumar, S., Tripathi, G. and McTernan, P.G. 2011. Mitochondrial bioenergetics changes are induced by metabolic endotoxinaemia contributing to mitochondrial stress and dysfunction in human adipocytes. 47th Annual Meeting of the EASD. Lisbon 12 - 16 Sep 2011 Springer. https://doi.org/10.1007/s00125-011-2276-4

Adiposity and diabetic status influences PLA2 isoforms in human abdominal subcutaneous and omental adipose tissue
Kumsaiyai, W., Harte, A.L., Saravanan, P., Kyrou, I., Aldaghri, N., Kumar, S., Tripathi, G. and McTernan, P.G. 2011. Adiposity and diabetic status influences PLA2 isoforms in human abdominal subcutaneous and omental adipose tissue. 47th Annual Meeting of the EASD. Lisbon 12 - 16 Sep 2011 Springer. https://doi.org/10.1007/s00125-011-2276-4

Folate and vitamin B12 imbalance induces endoplasmic reticulum stress in human adipocytes
McCarthy, C., Adaikalakoteswari, A., Moore, J., Brown, A.L., Brown, A., McTernan, P.G., Saravanan, P. and Tripathi, G. 2011. Folate and vitamin B12 imbalance induces endoplasmic reticulum stress in human adipocytes. 47th Annual Meeting of the EASD. Lisbon 12 - 16 Sep 2011 Springer. https://doi.org/10.1007/s00125-011-2276-4

Acute and chronic saturated fatty acid treatment as a key instigator of the TLR-mediated inflammatory response in human adipose tissue, in vitro
Youssef-Elabd, E.M., McGee, K.C., Tripathi, G., Abdalla, M.S., Sharada, H.M., Ashraf, E.A., Amin, I., Ceriello, A., O'Hare, J.P., Kumar, S., McTernan, P.G. and Harte, A.L. 2011. Acute and chronic saturated fatty acid treatment as a key instigator of the TLR-mediated inflammatory response in human adipose tissue, in vitro. Journal of Nutritional Biochemistry. 23 (1), pp. 39-50. https://doi.org/10.1016/j.jnutbio.2010.11.003

Glucose oscillations, more than constant high glucose, induce p53 activation and a metabolic memory in human endothelial cells
Schisano, B., Tripathi, G., McGee, K., McTernan, P.G. and Ceriello, A. 2011. Glucose oscillations, more than constant high glucose, induce p53 activation and a metabolic memory in human endothelial cells. Diabetologia. 54 (5), pp. 1219-1226. https://doi.org/10.1007/s00125-011-2049-0

Visfatin Is Regulated by Rosiglitazone in Type 2 Diabetes Mellitus and Influenced by NFκB and JNK in Human Abdominal Subcutaneous Adipocytes
McGee, K.C., Harte, A.L., da Silva, N.F., Al-Daghri, N., Creely, S.J., Kusminski, C.M., Tripathi, G., Levick, P.L., Khanolkar, M., Evans, M., Chittari, M.V., Patel, V., Kumar, S. and McTernan, P.G. 2011. Visfatin Is Regulated by Rosiglitazone in Type 2 Diabetes Mellitus and Influenced by NFκB and JNK in Human Abdominal Subcutaneous Adipocytes. PLoS ONE. 6 (6) e20287. https://doi.org/10.1371/journal.pone.0020287

Salicylate induces insulin sensitivity by alleviating endoplasmic reticulum (ER) stress in cultured primary human adipocytes
Tripathi, G., Alhusaini, S., McGee, K.C., Lois, K., Harte, A.L., McTernan, P.G. and Kumar, S. 2010. Salicylate induces insulin sensitivity by alleviating endoplasmic reticulum (ER) stress in cultured primary human adipocytes. Society for Endocrinology BES 2010. Manchester, UK 15 - 18 Mar 2010 BioScientifica Ltd..

The impact of saturated fatty acids and glucose on Toll-like receptor activated inflammatory pathways in human adipose tissue, in vitro
Harte, A., Youssef-Elabd, E., McGee, K.C., Tripathi, G., Ashour, E., Aballah, M., Sharada, H., Amin, A., Ceriello, A., O'Hare, P., Kumar, S. and McTernan, P.G. 2010. The impact of saturated fatty acids and glucose on Toll-like receptor activated inflammatory pathways in human adipose tissue, in vitro . Society for Endocrinology BES 2010. Manchester, UK 15 - 18 Mar 2010 BioScientifica Ltd..

Effect of Lipopolysaccharide and Salicylate on Mitochondrial Gene Expression in Primary Human Adipocytes
McGee, K.C., Tripathi, G., Harte, A.L., Langowska, M., Da Silva, N.F., Oscarsson, J., Clapham, J., Kumar, S. and McTernan, P.G. 2010. Effect of Lipopolysaccharide and Salicylate on Mitochondrial Gene Expression in Primary Human Adipocytes. American Diabetes Association (ADA) 70th Scientific Sessions. Orlando, Florida 25 - 29 Jun 2010 American Diabetes Association.

Human GLP-1 Analogue Liraglutide Alleviates Oxidative Stress Induced by Oscillating High Glucose in Human Umbilical Vascular Endothelial Cells
Schisano, B., Radford, C., Harte, A.L., Tripathi, G., McTernan, P.G., Knudsen, L.B. and Ceriello, A. 2010. Human GLP-1 Analogue Liraglutide Alleviates Oxidative Stress Induced by Oscillating High Glucose in Human Umbilical Vascular Endothelial Cells. American Diabetes Association (ADA) 70th Scientific Sessions. Orlando, Florida 25 - 29 Jun 2010 American Diabetes Association.

The Effects of Nutrients on Toll Like Receptor Activated Inflammatory Pathways in Human Adipose Tissue, In Vitro
Harte, A.L., Youssef-Elabd, E.M.M., McGee, K.C., Tripathi, G., Abdalla, M.S., Sharada, H.M., Ashour, E., Amin, A.I., Ceriello, A., O'Hare, J,P,, Kumar, S. and McTernan, P.G. 2010. The Effects of Nutrients on Toll Like Receptor Activated Inflammatory Pathways in Human Adipose Tissue, In Vitro. American Diabetes Association (ADA) 70th Scientific Sessions. Orlando, Florida 25 - 29 Jun 2010 American Diabetes Association.

Effect of Salicylate, Lipopolysaccharide and High Glucose on Endoplasmic Reticulum (ER) Stress in Cultured Primary Human Adipocytes
Alhusaini, S., McGee, K., Lois, K., Harte, A., McTernan, P., Kumar, S. and Tripathi, G. 2010. Effect of Salicylate, Lipopolysaccharide and High Glucose on Endoplasmic Reticulum (ER) Stress in Cultured Primary Human Adipocytes. American Diabetes Association (ADA) 70th Scientific Sessions. Orlando, Florida 25 - 29 Jun 2010 American Diabetes Association.

Elevated endotoxin levels in non-alcoholic fatty liver disease
Harte, A.L., da Silva, N.F., Creely, S.J., McGee, K.C., Billyard, T., Youssef-Elabd, E.M., Tripathi, G., Ashour, E., Abdalla, M.S., Sharada, H.M., Amin, A.I., Burt, A.D., Kumar, S., Day, C.P. and McTernan, P.G. 2010. Elevated endotoxin levels in non-alcoholic fatty liver disease. Journal of Inflammation. 7 (1), p. 15 15. https://doi.org/10.1186/1476-9255-7-15

Adiposity and insulin resistance correlate with telomere length in middle-aged Arabs: the influence of circulating adiponectin
Al-Attas, O., Al-Daghri, N., Alfadda, A., Pritlove, D., Harte, A., Tripathi, G., McTernan, P. and Kumar, S. 2010. Adiposity and insulin resistance correlate with telomere length in middle-aged Arabs: the influence of circulating adiponectin . European Journal of Endocrinology. 163 (4), pp. 601-607. https://doi.org/10.1530/EJE-10-0241

Insulin-Like Growth Factor-Binding Protein-5 Induces a Gender-Related Decrease in Bone Mineral Density in Transgenic Mice
Salih, D.A., Kasukawa, Y., Tripathi, G., Lovett, F.A., Anderson, N.F., Carter, E.J., Wergedal, J.E., Mohan, S. and Pell, J.M. 2010. Insulin-Like Growth Factor-Binding Protein-5 Induces a Gender-Related Decrease in Bone Mineral Density in Transgenic Mice. Endocrinology. 163 (4), pp. 601-607. https://doi.org/10.1210/en.2004-0816

Identification of Nesfatin-1 in Human and Murine Adipose Tissue: A Novel Depot-Specific Adipokine with Increased Levels in Obesity
Ramanjaneya, M., Chen, J., Brown, J., Tripathi, G., Hallschmid, M., Patel, S., Kern, W., Hillhouse, E.W., Lehnert, H., Tan, B.K. and Randeva, H.S. 2010. Identification of Nesfatin-1 in Human and Murine Adipose Tissue: A Novel Depot-Specific Adipokine with Increased Levels in Obesity. Endocrinology. 151 (7), pp. 3169-3180. https://doi.org/10.1210/en.2009-1358

Lipopolysaccharide, high glucose and saturated fatty acids induce endoplasmic reticulum stress in cultured primary human adipocytes: Salicylate alleviates this stress
Alhusaini, S., McGee, K., Schisano, B., Harte, A., McTernan, P., Kumar, S. and Tripathi, G. 2010. Lipopolysaccharide, high glucose and saturated fatty acids induce endoplasmic reticulum stress in cultured primary human adipocytes: Salicylate alleviates this stress. Biochemical and Biophysical Research Communications. 397 (3), pp. 472-478. https://doi.org/10.1016/j.bbrc.2010.05.138

Endoplasmic stress is induced by lipopolysaccharides and high glucose and is alleviated by salicylates in cultured primary human adipocytes
Alhusaini, S., Lois, K., McGee, K.C., McTernan, P.G., Kumar, S. and Tripathi, G. 2009. Endoplasmic stress is induced by lipopolysaccharides and high glucose and is alleviated by salicylates in cultured primary human adipocytes. 45th EASD Annual Meeting of the European Association for the Study of Diabetes. Vienna, Austria 30 Sep - 02 Oct 2009 Springer. https://doi.org/10.1007/s00125-009-1445-1

A novel role for p53 in the regulation of oxidative stress in vascular cells in response to glucose fluctuation
Schisano, B., Radford, C.R., Harte, A.L., Tripathi, G., McTernan, P.G. and Ceriello, A. 2009. A novel role for p53 in the regulation of oxidative stress in vascular cells in response to glucose fluctuation. 45th EASD Annual Meeting of the European Association for the Study of Diabetes. Vienna, Austria 30 Sep - 02 Oct 2009 Springer. https://doi.org/10.1007/s00125-009-1445-1

Acute and chronic saturated fatty acid treatment as a key instigator of the TLR mediated inflammatory response in human adipose tissue in vitro
Harte, A.L., Youssef-Elabd, E.M., McGee, K.C., Tripathi, G., Abdalla, M.S., Sharada, H.M., Ashour, E., Amin, A.I., O’Hare, J.P., Kumar, S. and McTernan, P.G. 2009. Acute and chronic saturated fatty acid treatment as a key instigator of the TLR mediated inflammatory response in human adipose tissue in vitro. 45th General Assembly of the European Association for the Study of Diabetes. Messe Wien, Vienna, Austria 03 Sep - 02 Oct 2009 Springer. https://doi.org/10.1007/s00125-010-1872-z

Metabolic endotoxaemia as a mediator of mitochondrial dysfunction in human adipose tissue, alleviated by salicylate
McGee, K.C., Tripathi, G., Creely,S.J., Harte, A.L., Langowska, M., Da Silva, N.F., Brown, A., Oscarsson, J., Clapham, J.C., Kumar, S. and McTernan, P.G. 2009. Metabolic endotoxaemia as a mediator of mitochondrial dysfunction in human adipose tissue, alleviated by salicylate. 45th General Assembly of the European Association for the Study of Diabetes. Messe Wien, Vienna, Austria 30 Sep - 02 Oct 2009 Springer. https://doi.org/10.1007/s00125-010-1872-z

Endoplasmic reticulum stress induced by hyperglycaemia and saturated fatty acids is alleviated by salicylates in cultured primary human adipocytes
Langowska, M., Alhusaini, S., McGee, K.C., Harte, A.L., McTernan, P.G., Kumar, S. and Tripathi, G. 2009. Endoplasmic reticulum stress induced by hyperglycaemia and saturated fatty acids is alleviated by salicylates in cultured primary human adipocytes. 45th General Assembly of the European Association for the Study of Diabetes. Messe Wien, Vienna, Austria 30 Sep - 02 Oct 2009 Springer. https://doi.org/10.1007/s00125-010-1872-z

Liraglutide down regulates endoplasmic reticulum stress in human endothelial cells exposed to hyperglycaemia
Schisano, B., Tripathi, G., Harte, A.L., McTernan, P.G., Knusden, L. and Ceriello, A. 2009. Liraglutide down regulates endoplasmic reticulum stress in human endothelial cells exposed to hyperglycaemia. 45th General Assembly of the European Association for the Study of Diabetes. Messe Wien, Vienna, Austria 30 Sep - 02 Oct 2009 Springer. https://doi.org/10.1007/s00125-010-1872-z

IGF-independent effects of insulin-like growth factor binding protein-5 (Igfbp5) in vivo
Tripathi, G., Salih, D.A.M., Drozd, A.C., Cosgrove, R.A., Cobb, L.C. and Pell, J.M. 2009. IGF-independent effects of insulin-like growth factor binding protein-5 (Igfbp5) in vivo. FASEB Journal. 23 (8), pp. 2616-2626. https://doi.org/10.1096/fj.08-114124

Obesity is associated with activation of innate immune pathway and ER stress in human abdominal subcutaneous adipose tissue
Tripathi, G., Kusminski, C.M., Harte, A.L., McGee, K.C., O'Hare, J.P., McTernan, P.G. and Kumar, S. 2008. Obesity is associated with activation of innate immune pathway and ER stress in human abdominal subcutaneous adipose tissue. 44th EASD Annual Meeting of the European Association for the Study of Diabetes. Rome, Italy 08 - 11 Sep 2008 Springer. https://doi.org/10.1007/s00125-008-1117-6

Endoplasmic reticulum stress and the innate immune signalling pathway in human abdominal adipose tissue: the effects of obesity
Kusminski, C., Schisano, B., Harte, A.L., Tripathi, G., Ceriello, A. and O'Hare, J.P. 2008. Endoplasmic reticulum stress and the innate immune signalling pathway in human abdominal adipose tissue: the effects of obesity. Society for Endocrinology BES 2008. Harrogate, UK 07 - 10 Apr 2008 BioScientifica Ltd..

Endoplasmic reticulum stress and the innate immune signalling pathway in human abdominal adipose tissue: the effects of obesity
Tripathi, G. 2008. Endoplasmic reticulum stress and the innate immune signalling pathway in human abdominal adipose tissue: the effects of obesity. Society for Endocrinology BES 2008. Harrogate, UK 07 - 10 Apr 2008 BioScientifica Ltd..

The effect of HIV status and the impact of ARV therapy on mitochondrial metabolism in human adipose tissue
Hill, M.J., McGee, K.C., Boothby, M., Higgins, P., Kusminski, C.M., Harte, A.L., Tripathi, G., Gathercole, L., Kumar, S., Shahmanesh, M. and McTernan, P.G. 2007. The effect of HIV status and the impact of ARV therapy on mitochondrial metabolism in human adipose tissue. 43rd EASD Annual Meeting of the European Association for the Study of Diabetes. Amsterdam, The Netherlands 18 - 21 Sep 2007 Springer. https://doi.org/10.1007/s00125-007-0809-7

Mitochondrial genes related to energy homoeostasis are dysregulated in obesity and type 2 diabetes in human adipose tissue
McGee, K.C., Hardo, F.J., Baker, A.R., Tripathi, G., Creely, S.J., da Silva, N.F., Kumar, S., Clapham, J.C. and McTernan, P.G. 2007. Mitochondrial genes related to energy homoeostasis are dysregulated in obesity and type 2 diabetes in human adipose tissue. Society for Endocrinology BES 2007. Birmingham, UK 05 - 08 Mar 2007 BioScientifica Ltd..

Escherichia coli having accession No. PTA 1579 and its use to produce polyhydroxybutyrate
Mahishi, L.H., Tripathi, G., Ramachander, T.V.N. and Rawal, S.K. 2006. Escherichia coli having accession No. PTA 1579 and its use to produce polyhydroxybutyrate. US Patent 7,135,316

Expression of mitochondrial genes related to energy homoeostasis are dysregulated in obesity and type 2 diabetes
McTernan, P.G., Hardo, F.J., Baker, A.R., McGee, K.C., Tripathi, G., Creely, S.J., da Silva, N.K., Kumar, S. and Clapham, J.C. 2006. Expression of mitochondrial genes related to energy homoeostasis are dysregulated in obesity and type 2 diabetes. 42nd EASD Annual Meeting of the European Association for the Study of Diabetes. Copenhagen, Denmark 14 - 17 Sep 2006 Springer. https://doi.org/10.1007/s00125-006-0358-5

Convergence of Igf2 expression and adhesion signalling via RhoA and p38 MAPK enhances myogenic differentiation
Lovett, F.A., Gonzalez, I., Salih, D.A.M., Cobb, L.J., Tripathi, G., Cosgrove, R.A., Murrell, A., Kilshaw, P.J. and Pell, J.M. 2006. Convergence of Igf2 expression and adhesion signalling via RhoA and p38 MAPK enhances myogenic differentiation. Journal of Cell Science. 119, pp. 4828-4840. https://doi.org/10.1242/jcs.03278

The Role of Insulin-Like Growth Factor Binding Proteins in Development
Pell, J.M., Salih, D.A.M., Cobb, L.J., Tripathi, G. and Drozd, A. 2005. The Role of Insulin-Like Growth Factor Binding Proteins in Development. Reviews in Endocrine and Metabolic Disorders. 6 (3), pp. 189-198. https://doi.org/10.1007/s11154-005-3050-z

Global Role of the Protein Kinase Gcn2 in the Human Pathogen Candida albicans
Tournu, H., Tripathi, G., Bertram, G., Macaskill, S., Mavor, A., Walker, L., Odds, F.C., Gow, N.A.R. and Brown, A.J.P. 2005. Global Role of the Protein Kinase Gcn2 in the Human Pathogen Candida albicans. Eukaryotic Cell. 4 (10), pp. 1687-1696. https://doi.org/10.1128/EC.4.10.1687-1696.2005

IGF-independent acceleration of myogenesis by IGFBP-5: modulation of cell survival and differentiation signalling pathways
Cobb, L.J., Gonzalez, I., Tripathi, G., Lovett, F.A., Salih, D.A.M., Godwin, K.S. and Pell, J.M. 2004. IGF-independent acceleration of myogenesis by IGFBP-5: modulation of cell survival and differentiation signalling pathways. Endocrine Society, Diabetes UK and Growth Factor Joint Conference. London, UK 01 - 03 Nov 2004

IGF-independent effects of insulin-like growth factor binding protein-5 (Igfbp5) in vivo
Tripathi, G., Salih, D.A.M., Drozd, A.C., Cosgrove, R.A., Cobb, L.C. and Pell, J.M. 2004. IGF-independent effects of insulin-like growth factor binding protein-5 (Igfbp5) in vivo. ENDO 2004: The Endocrine Society 86th Annual Meeting. New Orleans, USA 15 - 19 Jun 2004

Novel E. coli having accession no. PTA 1579 and its use to produce PHB
Mahishi, L.H., Tripathi, G., Ramachander, T.V.N. and Rawal, S.K. 2004. Novel E. coli having accession no. PTA 1579 and its use to produce PHB. US Patent No. 6,756,222

Process for the production of polyhydroxyoctanoate by Streptomyces lividans
Tripathi, G., Mahishi, L.H., Ramachander, T.V.N. and Rawal, S.K. 2004. Process for the production of polyhydroxyoctanoate by Streptomyces lividans. US Patent No. 6,692,945

Partitioning of IGFBP-5 actions in myogenesis: IGF-independent anti-apoptotic function
Cobb, L.J., Salih, D.A., González, I., Tripathi, G., Carter, E.J., Lovett, F., Holding, C. and Pell, J.M. 2004. Partitioning of IGFBP-5 actions in myogenesis: IGF-independent anti-apoptotic function. Journal of Cell Science. 117, pp. 1737-1746. https://doi.org/10.1242/jcs.01028

Akt2, a Novel Functional Link between p38 Mitogen-Activated Protein Kinase and Phosphatidylinositol 3-Kinase Pathways in Myogenesis
González, I., Tripathi, G., Carter, E.J., Holding, C., Lovett, F., Salih, D.A., Cobb, L.J. and Pell, J.M. 2004. Akt2, a Novel Functional Link between p38 Mitogen-Activated Protein Kinase and Phosphatidylinositol 3-Kinase Pathways in Myogenesis . Molecular and Cellular Biology. 24 (9), pp. 3607-3622. https://doi.org/10.1128/MCB.24.9.3607-3622.2004

Insulin-like growth factor-binding protein 5 (Igfbp5) compromises survival, growth, muscle development, and fertility in mice
Salih, D.A., Tripathi, G., Holding, C., González, M.I., Szestak, Tadge A.M., Carter, E.J., Cobb, L.J., Eisemann, Joan E. and Pell, J.M. 2004. Insulin-like growth factor-binding protein 5 (Igfbp5) compromises survival, growth, muscle development, and fertility in mice. Proceedings of the National Academy of Sciences. 101 (12), pp. 4314-4319. https://doi.org/10.1073/pnas.0400230101

Crosstalk between IGF signalling and cadherin-mediated cell adhesion promotes myogenic differentiation
Lovett, F., Gonzalez, M., Carter, E., Cobb, L., Salih, D., Tripathi, G., Holding, C. and Pell, J. 2003. Crosstalk between IGF signalling and cadherin-mediated cell adhesion promotes myogenic differentiation. 194th Meeting of the Society for Endocrinology and Society for Endocrinology joint with Diabetes UK Endocrinology and Diabetes Day. London, UK 03 - 05 Nov 2003 BioScientifica Ltd..

Poly(3-hydroxybutyrate) (PHB) synthesis by recombinant Escherichia coli harbouring Streptomyces aureofaciens PHB biosynthesis genes: Effect of various carbon and nitrogen sources
Mahishi, L.H., Tripathi, G. and Rawal, S.K. 2003. Poly(3-hydroxybutyrate) (PHB) synthesis by recombinant Escherichia coli harbouring Streptomyces aureofaciens PHB biosynthesis genes: Effect of various carbon and nitrogen sources. Microbiological Research. 158, pp. 19-27. https://doi.org/10.1078/0944-5013-00161

Proteomic analysis of the Gcn4-mediated response in Saccharomyces cerevisiae and Candida albicans
Yin, Z., Stead, D., Selwy, L ., Walker, J., Tripathi, G., McInerney, T., Cash, P. and Brown, A.J.P. 2003. Proteomic analysis of the Gcn4-mediated response in Saccharomyces cerevisiae and Candida albicans. Yeast. 20 (Suppl.1), p. S335.

Construction of a Streptomyces sp.–Escherichia coli conjugative shuttle vector and its application for recombinant biosynthesis of poly(3-hydroxyalkanoic acid)
Tripathi, G., Mahishi, L.H., Ramachander, T.V.N., Phadnis, S.H., Nambiyar, O.G.B. and Rawal, S.K. 2002. Construction of a Streptomyces sp.–Escherichia coli conjugative shuttle vector and its application for recombinant biosynthesis of poly(3-hydroxyalkanoic acid). Biotechnology Letters. 24 (3), pp. 213-218. https://doi.org/10.1023/A:1014117629700

Gcn4 co‐ordinates morphogenetic and metabolic responses to amino acid starvation in Candida albicans
Tripathi, G., Wiltshire, C., Macaskill, S., Tournu, H., Budge, S. and Brown, A.J.P. 2002. Gcn4 co‐ordinates morphogenetic and metabolic responses to amino acid starvation in Candida albicans. EMBO Journal. 21 (20), pp. 5448-5456. https://doi.org/10.1093/emboj/cdf507

Cloning and characterisation of CaGcn4
Tripathi, G., Wiltshire, C., Macaskill, S., Tournu, H., Budge, S. and Brown, A.J.P. 2000. Cloning and characterisation of CaGcn4. American Society for Microbiology. Seattle, USA 2000

Simple and efficient protocol for isolation of high molecular weight DNA from Streptomyces aureofaciens
Tripathi, G. and Rawal, S.K. 1998. Simple and efficient protocol for isolation of high molecular weight DNA from Streptomyces aureofaciens. Biotechnology Techniques. 12 (8), pp. 629-631. https://doi.org/10.1023/A:1008836214495