A Review of the Literature on HIV and Neuropsychological Functioning in Older Adults: Is More Research Needed?

Tragantzopoulou, P. and Giannouli, V. 2023. A Review of the Literature on HIV and Neuropsychological Functioning in Older Adults: Is More Research Needed? Problems of Psychology in the 21st Century. 17 (1), pp. 47-56. https://doi.org/10.33225/ppc/23.17.47

TitleA Review of the Literature on HIV and Neuropsychological Functioning in Older Adults: Is More Research Needed?
TypeJournal article
AuthorsTragantzopoulou, P. and Giannouli, V.
AbstractThe increase in the number of ageing people living with HIV and the documented neurocognitive impairments have highlighted the need to illuminate the existing findings and evaluate the impact that HIV has on older individuals. A review of the evidence for neuropsychological declines in memory, executive functions, attention and language in people aged 60 years or more was conducted. The databases MEDLINE, PsychINFO and Pubmed were searched for eligible studies based on keywords. Eight studies of low to high quality that looked at HIV+ older adults (≥ 60) were identified. The majority of older HIV+ adults experienced severe declines in all the cognitive domains under study. There were mixed results regarding the association among advancing age, functioning decline and HIV. Comparisons between HIV-infected and HIV-uninfected older adults showed that HIV+ subjects demonstrate higher scores of cognitive decline in memory, attention, language and executive functions. Further, comparisons among HIV+ adults, demographically matched individuals with mild cognitive impairment of the Alzheimer's type and healthy controls demonstrated that both disease groups perform worse, but the Alzheimer’s type group reports a greater decline in memory and language. Neuropsychological functioning in HIV+ adults presents great decline but studies on this population are limited. As individuals with HIV are increasingly living longer, studies should pay attention to these individuals and examine predictors of neuropsychological decline in the face of well-controlled interventions and treatments. Keywords: HIV, memory, neuropsychological function, executive functions, older adults
KeywordsGeneral Economics
Econometrics and Finance
JournalProblems of Psychology in the 21st Century
Journal citation17 (1), pp. 47-56
ISSN2538-7197
2029-8587
Year2023
PublisherScientia Socialis Ltd
Publisher's version
License
CC BY-NC 4.0
File Access Level
Open (open metadata and files)
Digital Object Identifier (DOI)https://doi.org/10.33225/ppc/23.17.47
Publication dates
Published online20 Dec 2023
Published in print23 Dec 2023

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