Maternal liver transplant: Another cause of discordant fetal sex determination using cell-free DNA.

Maria Neofytou, Nathalie Brison, Kris Van den Bogaert, Luc Dehaspe, Koen Devriendt, Anja Geerts and Joris R. Vermeesch 2018. Maternal liver transplant: Another cause of discordant fetal sex determination using cell-free DNA. Prenatal Diagnosis. 38 (2), pp. 148-150. https://doi.org/10.1002/pd.5194

TitleMaternal liver transplant: Another cause of discordant fetal sex determination using cell-free DNA.
TypeJournal article
AuthorsMaria Neofytou, Nathalie Brison, Kris Van den Bogaert, Luc Dehaspe, Koen Devriendt, Anja Geerts and Joris R. Vermeesch
Abstract

Noninvasive prenatal testing (NIPT) can very accurately determine fetal sex during pregnancy. We present an exceptional case where NIPT contradicts the ultrasound-based sex determination. The pregnant woman was recipient of a liver transplant from a male donor. Graft-derived cell-free DNA released into the maternal circulation clouded the NIPT-based sex determination. Hence, NIPT is not advisable when the pregnant mother underwent an organ transplant.

JournalPrenatal Diagnosis
Journal citation38 (2), pp. 148-150
ISSN1097-0223
0197-3851
Year2018
PublisherWiley
Digital Object Identifier (DOI)https://doi.org/10.1002/pd.5194
PubMed ID29239474
Web address (URL)https://pubmed.ncbi.nlm.nih.gov/29239474/
Publication dates
Published04 Jan 2018
Supplemental file
File Access Level
Open (open metadata and files)

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