Biomedical Sciences

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Colonic bacterial metabolites and host health

Article

Russell, W., Hoyles, L., Flint H, J. and Dumas M-E 2013. Colonic bacterial metabolites and host health. Current Opinion in Microbiology. 16 (3), pp. 246-254. https://doi.org/10.1016/j.mib.2013.07.002

Development of a pseudotype-based neutralisation assay kit for in-field vaccine evaluation and sero-surveillance of highly pathogenic viruses

Conference paper

Temperton, N.J., Mather, S., Scott, S. and Wright, E. 2013. Development of a pseudotype-based neutralisation assay kit for in-field vaccine evaluation and sero-surveillance of highly pathogenic viruses. Influenza 2013: One Influenza, One World, One health. Oxford, UK September 2013

Polyhydroxyalkanoates: the natural polymers produced by bacterial fermentation

Book chapter

Panchal, B., Bagdadi, A. and Roy, I. 2013. Polyhydroxyalkanoates: the natural polymers produced by bacterial fermentation. in: Advances in natural polymer Elsevier.

Oestrogen and immunomodulation: new mechanisms that impact on peripheral and central immunity

Article

Nadkarni, S. and McArthur, S. 2013. Oestrogen and immunomodulation: new mechanisms that impact on peripheral and central immunity. Current Opinion in Pharmacology. 13 (4), pp. 576-581. https://doi.org/10.1016/j.coph.2013.05.007

MicroRNA biotherapeutics: key challenges from a drug development perspective

Book chapter

Moschos, S.A. 2013. MicroRNA biotherapeutics: key challenges from a drug development perspective. in: Jones, L. and McKnight, A. (ed.) Biotherapeutics: recent developments using chemical and molecular biology London The Royal Society of Chemistry.

Kissorphin peptides for use in the treatment of Alzheimer's disease, Creutzfeldt-Jakob disease or diabetes mellitus

Patent

Milton, N.G.N. 2013. Kissorphin peptides for use in the treatment of Alzheimer's disease, Creutzfeldt-Jakob disease or diabetes mellitus.

Hepcidin transcription and peptide secretion are governed by different regulatory mechanisms

Article

Mehta, K., Patel, V., Busbridge Mark, Renshaw, D., Zariwala, M.G., Evans, R. and Farnaud, S. 2013. Hepcidin transcription and peptide secretion are governed by different regulatory mechanisms. American Journal of Hematology. 88, p. E55.

Development of a pseudotype neutralisation assay-based diagnostic kit for in-field vaccine evaluation and serosurveillance for highly pathogenic viruses

Conference paper

Mather, S., Temperton, N.J., Wright, E. and Scott, S. 2013. Development of a pseudotype neutralisation assay-based diagnostic kit for in-field vaccine evaluation and serosurveillance for highly pathogenic viruses. Society For General Microbiology Spring Meeting. Manchester, UK March 2013

Investigating the antibody neutralisation potential of a rabies virus lentiviral pseudotype: an international inter-laboratory trial

Conference paper

Healy, D.M., Horton, D.L., Banyard, A.C., Wright, E., Goddard, T., Evans, J., McElhinney, L.M. and Fooks, A.R. 2013. Investigating the antibody neutralisation potential of a rabies virus lentiviral pseudotype: an international inter-laboratory trial. Society For General Microbiology Spring Meeting. Manchester, UK March 2013

The lyssavirus glycoprotein: how significant are the currently characterised antigenic sites in the induction of neutralising antibodies?

Conference paper

Evans, J., Wright, E., Easton, A., Fooks, A.R. and Banyard, A.C. 2013. The lyssavirus glycoprotein: how significant are the currently characterised antigenic sites in the induction of neutralising antibodies? Society For General Microbiology Spring Meeting. Manchester, UK March 2013

Investigating the functionality and antigenicity of chimeric lyssavirus glycoproteins and their neutralisation profiles

Conference paper

Evans, J., Wright, E., Easton, A., Fooks, A.R. and Banyard, A.C. 2013. Investigating the functionality and antigenicity of chimeric lyssavirus glycoproteins and their neutralisation profiles. 15th International Negative Strand Virus Meeting. Granada, Spain June 2013

Investigating the functionality and antigenicity of chimeric lyssavirus glycoproteins and their neutralisation profiles

Conference paper

Evans, J., Wright, E., Easton, A., Fooks, A.R. and Banyard, A.C. 2013. Investigating the functionality and antigenicity of chimeric lyssavirus glycoproteins and their neutralisation profiles. Pseudotype viruses: applications and troubleshooting. London, UK October 2013

Melanocortin 3 receptor (MC3) activation effects on testicular testosterone and nitrite production in vitro

Conference poster

Dowejko, M.M., Smith, C.L., Getting, S.J., Le Tissier, P. and Murray, J.F. 2013. Melanocortin 3 receptor (MC3) activation effects on testicular testosterone and nitrite production in vitro. Society for Reproduction and Fertility (SRF) Annual Conference. Cambridge 11th July 2013

Identification of an essential endogenous regulator of blood-brain barrier integrity, and its pathological and therapeutic implications

Article

Cristante, E., McArthur, S., Mauro, C., Maggioli, E., Romero, I.A., Wylezinska-Arridge, M., Couraud, P.O., Lopez-Tremoleda, J., Christian, H.C., Weksler, B.B., Malaspina, A. and Solito, E. 2013. Identification of an essential endogenous regulator of blood-brain barrier integrity, and its pathological and therapeutic implications. Proceedings of the National Academy of Sciences of the United States of America. 110 (3), pp. 832-841. https://doi.org/10.1073/pnas.1209362110

Benzothiazole aniline-tetra(ethylene glycol) and 3-amino-1,2,4-triazole inhibit neuroprotection against amyloid peptides by catalase overexpression in vitro

Article

Chilumuri, A., Odell, M. and Milton, N.G.N. 2013. Benzothiazole aniline-tetra(ethylene glycol) and 3-amino-1,2,4-triazole inhibit neuroprotection against amyloid peptides by catalase overexpression in vitro. ACS chemical neuroscience. 4 (11), pp. 1501-1512. https://doi.org/10.1021/cn400146a

The role of neurotransmitters in protection against amyloid-β toxicity by KiSS-1 overexpression in SH-SY5Y neurons

Article

Chilumuri, A. and Milton, N.G.N. 2013. The role of neurotransmitters in protection against amyloid-β toxicity by KiSS-1 overexpression in SH-SY5Y neurons. ISRN Neuroscience. 2013 253210. https://doi.org/10.1155/2013/253210

Immunolocalization of kisspeptin associated with amyloid-β deposits in the pons of an Alzheimer’s disease patient

Article

Chilumuri, A., Ashioti, M., Nercessian, A.N. and Milton, N.G.N. 2013. Immunolocalization of kisspeptin associated with amyloid-β deposits in the pons of an Alzheimer’s disease patient. Journal of Neurodegenerative Diseases. 2013 879710. https://doi.org/10.1155/2013/879710

Chemerin15 inhibits neutrophil-mediated vascular inflammation and myocardial ischemia-reperfusion injury through ChemR23

Article

Cash, J.L., Bena, S., Headland, S.E., McArthur, S., Brancaleone, V. and Perretti, M. 2013. Chemerin15 inhibits neutrophil-mediated vascular inflammation and myocardial ischemia-reperfusion injury through ChemR23. EMBO reports. 14 (11), pp. 999-1007. https://doi.org/10.1038/embor.2013.138

Characterization of a monoclonal antibody cocktail for human rabies prophylaxis

Conference paper

Both, L., van Dolleweerd, C., Banyard, A.C., Wright, E., Fooks, A.R. and Ma, J.K.C. 2013. Characterization of a monoclonal antibody cocktail for human rabies prophylaxis. Pseudotype viruses: applications and troubleshooting. London, UK October 2013

Monoclonal antibodies for prophylactic and therapeutic use against viral infections

Article

Both, L., Banyard, A.C., van Dolleweerd, C., Wright, E., Ma, J.K.C. and Fooks, A.R. 2013. Monoclonal antibodies for prophylactic and therapeutic use against viral infections. Vaccine. 31 (12), pp. 1553-1559. https://doi.org/10.1016/j.vaccine.2013.01.025

Single domain antibody multimers confer protection against rabies infection

Journal article

Boruah, B.M., Liu, D., Ye, D., Gu, T.J., Jiang, C.L., Qu, M., Wright, E., Wang, W., He, W., Liu, C. and Gao, B. 2013. Single domain antibody multimers confer protection against rabies infection. PLoS ONE. 8 (8) e71383. https://doi.org/10.1371/journal.pone.0071383

The construction of chimeric rabies virus glycoproteins rescues Arctic-like rabies pseudovirus production

Conference paper

Bentley, E., Ali, R., Horton, D.L., Banyard, A.C. and Wright, E. 2013. The construction of chimeric rabies virus glycoproteins rescues Arctic-like rabies pseudovirus production. Pseudotype viruses: applications and troubleshooting. London, UK October 2013

Neuroprotective efficacy of the endogenous neuropeptide Urocortin in a oxygen-glucose deprivation model of transient cerebral ischaemia with reperfusion

Conference paper

Ashioti, M., Getting, S.J., Locke, I.C. and Milton, N.G.N. 2013. Neuroprotective efficacy of the endogenous neuropeptide Urocortin in a oxygen-glucose deprivation model of transient cerebral ischaemia with reperfusion. British Neuroscience Association 22nd Biennial Meeting. London 7th-10th April 2013

The construction of chimeric rabies virus glycoproteins rescues Arctic-like rabies pseudovirus production

Conference paper

Ali, R., Horton, D.L., Banyard, A.C. and Wright, E. 2013. The construction of chimeric rabies virus glycoproteins rescues Arctic-like rabies pseudovirus production. Society For General Microbiology Spring Meeting. Manchester, UK March 2013

Fibril formation and toxicity of the non-amyloidogenic rat amylin peptide

Article

Milton, N.G.N. and Harris, J.R. 2013. Fibril formation and toxicity of the non-amyloidogenic rat amylin peptide. Micron. 44, pp. 246-253. https://doi.org/10.1016/j.micron.2012.07.001

Annexin-A1 protein and its relationship to cortisol in human saliva

Journal article

Fowkes, R.C., Moradi-Bidhendi, N., Branceleone, V., Gulrez Zariwala, M., Brady, D., Jessop, D.S., Perretti, M., Renshaw, D. and Brancaleone, V. 2013. Annexin-A1 protein and its relationship to cortisol in human saliva. Psychoneuroendocrinology. 38 (5), pp. 722-727. https://doi.org/10.1016/j.psyneuen.2012.08.003

Chicken IFITM3 restricts influenza viruses and lyssaviruses in vitro

Journal article

Smith, S.E., Gibson, M.S., Wash, R.S., Ferrara, F., Wright, E., Temperton, N.J., Kellam, P. and Fife, M. 2013. Chicken IFITM3 restricts influenza viruses and lyssaviruses in vitro. Journal of Virology. 87 (23), pp. 12957 -12966. https://doi.org/10.1128/JVI.01443-13

Hepatic mitochondrial dysfunction induced by fatty acids and ethanol

Article

Gyamfi, D., Everitt, H.E., Tewfik, I., Clemens, D.L. and Patel, V. 2012. Hepatic mitochondrial dysfunction induced by fatty acids and ethanol. Free Radical Biology & Medicine. 53 (11), pp. 2131-2145. https://doi.org/10.1016/j.freeradbiomed.2012.09.024

Genomic biomarkers for patient selection and stratification: the cancer paradigm

Article

Moschos, S.A. 2012. Genomic biomarkers for patient selection and stratification: the cancer paradigm. Bioanalysis. 4 (20), pp. 2499-2511. https://doi.org/10.4155/bio.12.241

A phenotype–genotype correlation of ADAMTS13 mutations in congenital thrombotic thrombocytopenic purpura patients treated in the United Kingdom

Article

Camilleri, R., Scully, M., Thomas, M., Mackie, I.J., Liesner, R., Chen, W., Manns, K. and Machin, S.J. 2012. A phenotype–genotype correlation of ADAMTS13 mutations in congenital thrombotic thrombocytopenic purpura patients treated in the United Kingdom. Journal of Thrombosis and Haemostasis. 10 (9), pp. 1792-1801. https://doi.org/10.1111/j.1538-7836.2012.04852.x

Investigation of the impact of feeding Lactobacillus plantarum CRL 1815 encapsulated in microbially derived polymers on the rat faecal microbiota

Article

Jiménez-Pranteda, M.L., Aguilera, M., McCartney, A.L., Hoyles, L., Jiménez-Valera, M., Náder-Macías, M.E., Ramos-Cormenzana, A. and Monteoliva-Sánchez, M. 2012. Investigation of the impact of feeding Lactobacillus plantarum CRL 1815 encapsulated in microbially derived polymers on the rat faecal microbiota. Journal of Applied Microbiology. 113 (2), pp. 399-410. https://doi.org/10.1111/j.1365-2672.2012.05343.x

Investigations of the human faecal Coriobacteriaceae population

Conference poster

McCartney, A.L., Thorasin, T. and Hoyles, L. 2012. Investigations of the human faecal Coriobacteriaceae population. Exploring Human Host–Microbiome Interactions in Health and Disease. Cambridge, UK 08 May 2012

In vivo pharmacology: reaping the benefits of analysis at the cell type level

Article

Moschos, S.A. 2012. In vivo pharmacology: reaping the benefits of analysis at the cell type level. Pharmacology Matters Newsletter. 5 (1), pp. 15-16.

Increased transferrin-bound iron uptake in HepG2 cells is followed by an increase in expression of the iron hormone hepcidin pre-and post-translationally

Conference paper

Mehta, K., Patel, V., Busbridge Mark, Renshaw, D., Zariwala, M., Evans, R. and Farnaud, S. 2012. Increased transferrin-bound iron uptake in HepG2 cells is followed by an increase in expression of the iron hormone hepcidin pre-and post-translationally. European Iron Club Annual Meeting 2012. Rennes, France 29 - 31 Aug 2012

Comparison of iron absorption from iron supplement preparations using an in vitro Caco-2 model

Conference paper

Zariwala, M., Farnaud, S. and Renshaw, D. 2012. Comparison of iron absorption from iron supplement preparations using an in vitro Caco-2 model. European Iron Club Annual Meeting 2012. Rennes, France 29 - 31 Aug 2012

DPPIV and macronutrients regulate the expression of PYY3–36 in human gut epithelial cells

Conference paper

Kosicka, A., Renshaw, D. and Zariwala, M. 2012. DPPIV and macronutrients regulate the expression of PYY3–36 in human gut epithelial cells. Society for Endocrinology BES 2012. Harrogate, UK Mar - Apr 2012 BioScientifica Ltd.. https://doi.org/10.1530/endoabs.31.P197

Ac 2-26, an annexin A1-derived peptide, reduces inflammation in human SGBS adipocytes after hypoxia treatment

Conference paper

Kosicka-Knox, A., Cunliffe, A., Mackenzie, R., Zariwala, M. and Renshaw, D. 2012. Ac 2-26, an annexin A1-derived peptide, reduces inflammation in human SGBS adipocytes after hypoxia treatment. 15th International & 14th European Congress of Endocrinology. Florence, Italy 05 - 09 May 2012 BioScientifica Ltd..

Annexin A1, an anti-inflammatory regulator, is expressed in human adipocytes

Conference paper

Kosicka-Knox, A., Cunliffe, A., Mackenzie, R., Zariwala, M. and Renshaw, D. 2012. Annexin A1, an anti-inflammatory regulator, is expressed in human adipocytes. Society for Endocrinology BES 2012. Harrogate, UK Mar - Apr 2012

Phenanthrene degradation and concomitant electricity generation using a bioelectrochemical process

Conference poster

Adelaja, O., Keshavarz, T. and Kyazze, G. 2012. Phenanthrene degradation and concomitant electricity generation using a bioelectrochemical process . Electrochem 2012 - Electrochemical Horizons. Dublin 02 - 04 Sep 2012 Royal Society of Chemistry.

Intermittent exercise with and without hypoxia improves insulin sensitivity in individuals with type 2 diabetes

Journal article

MacKenzie, R., Maxwell, N.S., Castle, P.C., Elliott, B., Brickley, G. and Watt, P.W. 2012. Intermittent exercise with and without hypoxia improves insulin sensitivity in individuals with type 2 diabetes. Journal of Clinical Endocrinology and Metabolism. 97 (4), pp. 46-55. https://doi.org/10.1210/jc.2011-2829


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