Preferences of healthy men for two different endocrine treatment options offered for locally advanced prostate cancer

Jenkins, V.A., Followfield, L., Edginton, T.L., Payne, H. and Hamilton, E. 2005. Preferences of healthy men for two different endocrine treatment options offered for locally advanced prostate cancer. Current Medical Research and Opinion. 21 (9), pp. 1329-1336.

TitlePreferences of healthy men for two different endocrine treatment options offered for locally advanced prostate cancer
AuthorsJenkins, V.A., Followfield, L., Edginton, T.L., Payne, H. and Hamilton, E.
Abstract

Objective: The aim of this study was to determine whether healthy men would prefer either luteinizing hormone releasing hormone analogues (LHRHa) or non-steroidal anti-androgen therapy (NSAA) should they hypothetically develop locally advanced prostate cancer.

Participants and methods: A representative sample of 180 men without prostate cancer (68% over 65 years of age, range 50–90 years), read two scenarios describing LHRHa or NSAA treatments for locally advanced prostate cancer. Participants chose which drug treatment they hypothetically would prefer, gave a reason for their choice and indicated the degree to which they wanted to avoid side effects specific to each drug.

Results: Eighty-six per cent (156/180) of the men chose NSAA therapy, 7% (12/180) chose LHRHa therapy and 7% (12/180) could not decide. The main reason men chose LHRHa therapy was because of the method of administration (9/12) whereas those who chose NSAA therapy cited avoidance of the side effects associated with LHRHa treatment (115/156). The side effects, ranked in order of importance, that men who chose NSAA therapy most wanted to avoid included risk of potential fractures (85%), reduced physical strength (76%), decreased sexual interest (56%), impotence (51%), hot flushes (49%), breast enlargement (17%) and breast tenderness (13%).

Conclusion: Although this project was a hypothetical study, several important issues emerged from the data that are relevant to patient choice. Men should be fully informed about the side-effect profiles of different endocrine treatments, involved in decision making and allowed to choose therapies less likely to cause side effects they would prefer to avoid.

JournalCurrent Medical Research and Opinion
Journal citation21 (9), pp. 1329-1336
ISSN0300-7995
YearSep 2005
Digital Object Identifier (DOI)doi:10.1185/030079905X59058
Publication dates
PublishedSep 2005

Related outputs

New Ways of Being a Man: “Positive” Hegemonic Masculinity in Meditation-based Communities of Practice
Lomas, Tim, Cartwright, T., Edginton, T.L. and Ridge, Damien T. 2016. New Ways of Being a Man: “Positive” Hegemonic Masculinity in Meditation-based Communities of Practice. Men and Masculinities. 19 (3), pp. 289-310.

Cultivating equanimity through mindfulness meditation: a mixed methods enquiry into the development of decentring capabilities in men
Lomas, T., Edginton, T.L., Cartwright, T. and Ridge, Damien T. 2015. Cultivating equanimity through mindfulness meditation: a mixed methods enquiry into the development of decentring capabilities in men. International Journal of Wellbeing. 5 (3), pp. 88-106.

Engagement with meditation as a positive health trajectory: Divergent narratives of progress in male meditators
Lomas, Tim, Ridge, Damien T., Cartwright, T. and Edginton, T.L. 2014. Engagement with meditation as a positive health trajectory: Divergent narratives of progress in male meditators. Psychology & Health. 29 (2), pp. 218-236.

Men developing emotional intelligence through meditation? Integrating narrative, cognitive and electroencephalography (EEG) evidence
Lomas, Tim, Edginton, T.L., Cartwright, T. and Ridge, Damien T. 2014. Men developing emotional intelligence through meditation? Integrating narrative, cognitive and electroencephalography (EEG) evidence. Psychology of Men & Masculinity. 15 (2), pp. 213-224.

A religion of wellbeing? The appeal of Buddhism to men in London, United Kingdom
Lomas, Tim, Cartwright, T., Edginton, T.L. and Ridge, Damien T. 2014. A religion of wellbeing? The appeal of Buddhism to men in London, United Kingdom. Psychology of Religion and Spirituality. 6 (3), pp. 198-207.

A qualitative analysis of experiential challenges associatedwith meditation practice
Lomas, Tim, Cartwright, T., Edginton, T.L. and Ridge, Damien T. 2014. A qualitative analysis of experiential challenges associatedwith meditation practice. Mindfulness.

Investigating the impact of nicotine on executive functions using a novel virtual reality assessment
Jansari, A.S., Froggat, D., Edginton, T.L. and Dawkins, L. 2013. Investigating the impact of nicotine on executive functions using a novel virtual reality assessment. Addiction. 108 (5), pp. 977-984.

I was so done in that I just recognized it very plainly, “You need to do something”’: men’s narratives of struggle, distress and turning to meditation
Lomas, Tim, Cartwright, T., Edginton, T.L. and Ridge, Damien T. 2013. I was so done in that I just recognized it very plainly, “You need to do something”’: men’s narratives of struggle, distress and turning to meditation. Health. 17 (2), pp. 191-208.

Men behaving well? Journeys towards constructive engagement with well-being through meditation
Lomas, T., Cartwright, T., Edginton, T.L. and Ridge, Damien T. 2011. Men behaving well? Journeys towards constructive engagement with well-being through meditation. BSA Medical Sociology Group 43rd Annual Conference 2011. University of Chester 14 - 16 Sep 2011

Men behaving well? Journeys towards constructive engagement with well-being through meditation
Lomas, T., Cartwright, T., Edginton, T.L. and Ridge, Damien T. 2011. Men behaving well? Journeys towards constructive engagement with well-being through meditation. 7th Biennial Conference of the International Society of Critical Health Psychology (ISCHP). Adelaide, South Australia 18 -20 Apr 2011

Men behaving well?: Journeys towards constructive engagement with well-being through meditation
Lomas, T., Cartwright, T., Edginton, T.L. and Ridge, Damien T. 2010. Men behaving well?: Journeys towards constructive engagement with well-being through meditation. Psychology & Health. 25 (S1), p. 265.

Spina bifida and hydrocephalus
Edginton, T.L. 2010. Spina bifida and hydrocephalus. in: Davis, A. and D'Amato, R.C. (ed.) Handbook of paediatric neuropsychology: applications of cognitive neuroscience Springer.

Current concepts in Alzheimer's disease: a multidisciplinary review
Minati, L., Edginton, T.L., Bruzzone, M.G. and Giaconne, G. 2009. Current concepts in Alzheimer's disease: a multidisciplinary review. American Journal of Alzheimer's Disease and Other Dementias. 24 (2), pp. 95-121.

An investigation of the effects of nicotine on executive processes using a virtual reality environment
Edginton, T.L., Nikolla, D. and Jansari, A.S. 2007. An investigation of the effects of nicotine on executive processes using a virtual reality environment. 2007 Psychobiology 22nd Annual Scientific Meeting. Windermere, UK 03 - 05 Sep 2007

An investigation of a non-selective imagery impairment on strategic and autobiographical memory processes following posterior frontal lobe craniotomy
Edginton, T.L. 2007. An investigation of a non-selective imagery impairment on strategic and autobiographical memory processes following posterior frontal lobe craniotomy. International Neuropsychological Society Meeting. Bilbao, Spain Jul 2007

Does neoadjuvant hormone therapy for early prostate cancer affect cognition? Results from a pilot study
Jenkins, V.A., Bloomfield, D.J., Shilling, V.M. and Edginton, T.L. 2005. Does neoadjuvant hormone therapy for early prostate cancer affect cognition? Results from a pilot study. BJU international. 96 (1), pp. 48-53.

The cognitive effects of reversible hormone therapy for prostate cancer
Edginton, T.L. 2004. The cognitive effects of reversible hormone therapy for prostate cancer. 7th World Congress of Psycho-Oncology. Copenhagen, Denmark 25 - 28 Aug 2004

Separate and combined effects of scopolamine and nicotine on retrieval-induced forgetting
Edginton, T.L. and Rusted, J.M. 2003. Separate and combined effects of scopolamine and nicotine on retrieval-induced forgetting. Psychopharmacology. 170 (4), pp. 351-357.

Efficient remembering: nicotine improves suppression of irrelevancies
Edginton, T.L. and Rusted, J.M. 2002. Efficient remembering: nicotine improves suppression of irrelevancies. Neurobiology of Aging. 23 (Supplement 1), p. S123.

Effects of nicotine on inhibitory processes in human memory
Edginton, T.L. 2001. Effects of nicotine on inhibitory processes in human memory. Journal of Psychopharmacology. 15 (Supplement), p. A55.

Permalink - https://westminsterresearch.westminster.ac.uk/item/92903/preferences-of-healthy-men-for-two-different-endocrine-treatment-options-offered-for-locally-advanced-prostate-cancer


Share this
Tweet
Email