Determinants of Influenza and Pertussis Vaccination Uptake in Pregnancy: A Multicenter Questionnaire Study of Pregnant Women and Healthcare Professionals

Wilcox, C.R., Calvert, A., Metz, J., Kilich, E., MacLeod, R., Beadon, K, Heath, P.T., Khalil, A., Finn, A., Snape, M.D., Vandrevala, T., Nadarzynski, T., Coleman, M.A. and Jones, C.E. 2019. Determinants of Influenza and Pertussis Vaccination Uptake in Pregnancy: A Multicenter Questionnaire Study of Pregnant Women and Healthcare Professionals. The Pediatric Infectious Disease Journal. 38 (6), pp. 625-630. doi:10.1097/INF.0000000000002242

TitleDeterminants of Influenza and Pertussis Vaccination Uptake in Pregnancy: A Multicenter Questionnaire Study of Pregnant Women and Healthcare Professionals
TypeJournal article
AuthorsWilcox, C.R., Calvert, A., Metz, J., Kilich, E., MacLeod, R., Beadon, K, Heath, P.T., Khalil, A., Finn, A., Snape, M.D., Vandrevala, T., Nadarzynski, T., Coleman, M.A. and Jones, C.E.
Abstract

Introduction: Uptake rates of antenatal vaccination remain suboptimal. Our aims were to determine (1) the acceptability of routine vaccination among pregnant women, (2) the confidence of maternity healthcare professionals (HCPs) discussing vaccination and (3) HCP opinion regarding the optimum healthcare site for vaccine administration.

Methods: Separate questionnaires for pregnant women and HCPs were distributed within 4 national health service (NHS) trusts in South England (July 2017 to January 2018).

Results: Responses from 314 pregnant women and 204 HCPs (18% obstetricians, 75% midwives, 7% unidentified) were analyzed. Previous/intended uptake of influenza and pertussis vaccination was 78% and 92%, respectively. The commonest reason for declining vaccination was feared side effects for their child. White British women (79%) were significantly more accepting of influenza [85% vs. 61%; odds ratio (OR) 3.25; 95% confidence interval [CI], 1.67–6.32] and pertussis vaccination (96% vs. 83%; OR 4.83; 95% CI: 1.77–13.19) compared with nonwhite British women. Among HCPs, 25% were slightly or not at all confident discussing vaccination. Obstetricians felt significantly more confident discussing pertussis vaccination than midwives (68% vs. 55% were very/moderately confident; OR 2.05; 95% CI: 1.02–4.12). Among HCPs, 53%, 25% and 16% thought vaccines should be administered in primary care (general practice), community midwifery and in hospital, respectively.

Conclusion: Misconceptions exist regarding safety/efficacy of antenatal vaccination, and framing information towards the child’s safety may increase uptake. Education of HCPs is essential, and vaccine promotion should be incorporated into routine antenatal care, with an emphasis on women from ethnic minorities. Administration of vaccines in primary care presents logistical barriers; however, support for alternative sites appears low among HCPs.

KeywordsVaccination; Pregnancy; Respiratory Syncytial Virus; RSV; Clinical Trials; Attitudes
JournalThe Pediatric Infectious Disease Journal
Journal citation38 (6), pp. 625-630
ISSN0891-3668
Year2019
PublisherWolters Kluwer
Digital Object Identifier (DOI)doi:10.1097/INF.0000000000002242
Publication dates
Published01 Jun 2019

Related outputs

Digital Health Psychology
Yardley, L., Bradbury, K., Nadarzynski, T. and Hunter, C. 2019. Digital Health Psychology. in: Revenson, T.A. and Gerung, R.A.R. (ed.) Handbook of Health Psychology New York Routledge. pp. 519-525

Preferences for HIV testing services among men who have sex with men in the UK: A discrete choice experiment
Miners, A., Nadarzynski, T., Witzel, C, Phillips, A.N., Cambiano, V., Rodger, A.J. and Llewellyn, C.D. 2019. Preferences for HIV testing services among men who have sex with men in the UK: A discrete choice experiment. PLoS Medicine. 16 (4), p. e1002779. doi:10.1371/journal.pmed.1002779

Mixed-methods study in England and Northern Ireland to understand young men who have sex with men’s knowledge and attitudes towards human papillomavirus vaccination
Kesten, J.M., Flannagan, C., Ruane-McAteer, E., Merriel, S.W.D., Nadarzynski, T., Shapiro, G.K., Rosberger, Z. and Prue, G. 2019. Mixed-methods study in England and Northern Ireland to understand young men who have sex with men’s knowledge and attitudes towards human papillomavirus vaccination. BMJ Open. 9 (e025070). doi:10.1136/bmjopen-2018-025070

Targeted advertisement of chlamydia screening on social media: A mixed-methods analysis
Nadarzynski, T., Burton, J., Henderson, K., Zimmerman, D., Hill, O. and Graham, C. 2019. Targeted advertisement of chlamydia screening on social media: A mixed-methods analysis. Digital Health. 5, pp. 1-10. doi:10.1177/2055207619827193

Determinants of influenza and pertussis vaccination uptake in pregnancy: a multi-centre questionnaire study of pregnant women and healthcare professionals
Wilcox, C.R., Calvert, A., Metz, J., Kilich, E., MacLeod, R., Beadon, K., Heath, P.T., Khalil, A., Finn, A., Snape, M.D., Vandrevala, T., Nadarzynski, T., Coleman, M.A. and Jones, C.E. 2019. Determinants of influenza and pertussis vaccination uptake in pregnancy: a multi-centre questionnaire study of pregnant women and healthcare professionals. The Pediatric Infectious Disease Journal. 38 (6), pp. 625-630. doi:10.1097/INF.0000000000002242

Men who have sex with men who do not access sexual health clinics nor disclose sexual orientation are unlikely to receive the HPV vaccine in the UK
Nadarzynski, T., Smith, H., Richardson, D., Bremner, S. and Llewellyn, C. 2018. Men who have sex with men who do not access sexual health clinics nor disclose sexual orientation are unlikely to receive the HPV vaccine in the UK. Vaccine. 36 (33), pp. 5065-5070. doi:10.1016/j.vaccine.2018.06.075

Permalink - https://westminsterresearch.westminster.ac.uk/item/qqyy4/determinants-of-influenza-and-pertussis-vaccination-uptake-in-pregnancy-a-multicenter-questionnaire-study-of-pregnant-women-and-healthcare-professionals


Restricted files

Accepted author manuscript
Under embargo until 01 Jun 2020

Share this
Tweet
Email