Vaccine acceptability, uptake and completion amongst men who have sex with men: A systematic review, meta-analysis and theoretical framework

Nadarzynski, T., Frost, M., Miller, Danny, Wheldon, Christopher W., Wiernik, Brenton M., Zou, Huachun, Richardson, Daniel, Marlow, L., Smith, Helen, Jones, C. and Llewellyn, C. 2021. Vaccine acceptability, uptake and completion amongst men who have sex with men: A systematic review, meta-analysis and theoretical framework. Vaccine. 39 (27), pp. 3565-3581. https://doi.org/10.1016/j.vaccine.2021.05.013

TitleVaccine acceptability, uptake and completion amongst men who have sex with men: A systematic review, meta-analysis and theoretical framework
TypeJournal article
AuthorsNadarzynski, T., Frost, M., Miller, Danny, Wheldon, Christopher W., Wiernik, Brenton M., Zou, Huachun, Richardson, Daniel, Marlow, L., Smith, Helen, Jones, C. and Llewellyn, C.
AbstractBackground Due to an increased risk of sexually transmitted infections (STIs), gay, bisexual and other men who have sex with men (MSM) have been recommended to receive vaccinations against human papillomavirus, meningitis C and hepatitis A/B. This review aimed to compare the rates of vaccine acceptability, uptake and completion, and to identify determinants of vaccine outcomes specific to MSM to inform a theoretical framework. Methods In January 2020 four databases were explored to identify vaccination behaviours and associated factors among MSM. A narrative systematic review and meta-analysis were performed. Data were synthesised for theoretical modelling. Results Seventy-eight studies, mostly from the USA, were included. The average vaccine acceptability was 63% (median = 72%, range: 30%-97%), vaccine uptake 45% (median = 42%, range: 5%-100%) and vaccine completion 47% (median = 45%, range: 12%-89%). Six categories of factors associated with vaccination acceptability, uptake and completion were conceptualised: Individual (e.g., demographic and psychosocial); Interpersonal (e.g., peer education); Healthcare provider (e.g., vaccine recommendation); Organisational and practice setting (e.g., routine collection of patient sexual orientation information that is integrated into a clinical decision support system); Community environment (e.g., targeted health promotion campaigns); and National, state and local policy environment (e.g., public health guidelines targeting MSM). Conclusion Despite overall high levels of acceptability, uptake and completion rates were below targets predicted by cost-effectiveness modelling across all recommended vaccines. These parameters may need to be adjusted for more precise estimations of cost-effectiveness. Addressing the multiple levels of determinants, as outlined in our theoretical framework, will help guide interventions to increase vaccine completion among MSM.
KeywordsGay
Bisexual
MSM
HPV
Meningitis
HAV
HBV
vaccination
JournalVaccine
Journal citation39 (27), pp. 3565-3581
ISSN0264-410X
Year2021
PublisherElsevier
Accepted author manuscript
License
CC BY-NC-ND 4.0
File Access Level
Open (open metadata and files)
Digital Object Identifier (DOI)https://doi.org/10.1016/j.vaccine.2021.05.013
Publication dates
Published online24 May 2021
Published in print16 Jun 2021

Related outputs

Sexual healthcare professionals’ views on the rapid provision of remote services at the beginning of COVID-19 pandemic: A mixed-methods study
Lunt, Alexandria, Llewellyn, C., Bayley, Jake and Nadarzynski, T. 2021. Sexual healthcare professionals’ views on the rapid provision of remote services at the beginning of COVID-19 pandemic: A mixed-methods study. International Journal of STD & AIDS. https://doi.org/10.1177/09564624211023018

Barriers and facilitators to engagement with artificial intelligence (AI)-based chatbots for sexual and reproductive health advice: A qualitative analysis
Nadarzynski, T., Puentes, V., Pawlak, I., Mendes, T., Montgomery, I., Bayley, J. and Ridge, Damien T. 2021. Barriers and facilitators to engagement with artificial intelligence (AI)-based chatbots for sexual and reproductive health advice: A qualitative analysis. Sexual Health.

Using protection motivation theory to explain the intention to initiate human papillomavirus vaccination among men who have sex with men in China.
Huang, Ruonan, Wang, Zhenyu, Yuan, Tanwei, Nadarzynski, Tom, Qian, Han-Zhu, Li, Peiyang, Meng, Xiaojun, Wang, Guanghui, Zhou, Yepeng, Luo, Danyang, Wang, Ying, Cai, Yong and Zou, Huachun 2021. Using protection motivation theory to explain the intention to initiate human papillomavirus vaccination among men who have sex with men in China. Tumour Virus Research. 12 200222. https://doi.org/10.1016/j.tvr.2021.200222

Does online sexually transmitted infection screening compromise care? A service evaluation comparing the management of chlamydial infection diagnosed online and in clinic
Gasmelsid, N., Moran, B., Nadarzynski, T., Patel, R. and Foley, E. 2021. Does online sexually transmitted infection screening compromise care? A service evaluation comparing the management of chlamydial infection diagnosed online and in clinic. International Journal of STD & AIDS. 32 (6), pp. 528-532. https://doi.org/10.1177/0956462420980929

Perceived barriers and facilitators to female condoms among UK based healthcare professionals
Burton, Jack, Bedford, Rowena, Graham, C. and Nadarzynski, T. 2020. Perceived barriers and facilitators to female condoms among UK based healthcare professionals. The European Journal of Contraception & Reproductive Health Care. 25 (4), pp. 299-304. https://doi.org/10.1080/13625187.2020.1777966

Acceptability of remote prescribing and postal delivery services for contraceptive pills and treatment of uncomplicated Chlamydia trachomatis
Nadarzynski, T., Symonds, Y., Carroll, R., Gibbs, J., Kidsley, S. and Graham, C. A. 2020. Acceptability of remote prescribing and postal delivery services for contraceptive pills and treatment of uncomplicated Chlamydia trachomatis. BMJ Sexual and Reproductive Health. 47, pp. 185-192. https://doi.org/10.1136/bmjsrh-2020-200687

Understanding the diverse sexual repertoires of men who have sex with men, trans and gender-diverse groups is important for sexually transmitted infection prevention
Richardson, D., Nambiar, K. and Nadarzynski, T. 2020. Understanding the diverse sexual repertoires of men who have sex with men, trans and gender-diverse groups is important for sexually transmitted infection prevention. BMJ Sexual & Reproductive Health. Advanced online publication. https://doi.org/10.1136/bmjsrh-2020-200804

Acceptability of artificial intelligence (AI)-enabled chatbots, video consultations and live webchats as online platforms for sexual health advice
Nadarzynski, T., Bayley, J., Llewellyn, C., Kidsley, S. and Graham, C.A. 2020. Acceptability of artificial intelligence (AI)-enabled chatbots, video consultations and live webchats as online platforms for sexual health advice. BMJ Sexual and Reproductive Health. 46, pp. 210-217. https://doi.org/10.1136/bmjsrh-2018-200271

Acceptability of artificial intelligence (AI)-led chatbot services in healthcare: A mixed-methods study
Nadarzynski, T., Miles, Oliver, Cowie, Aimee and Ridge, Damien 2019. Acceptability of artificial intelligence (AI)-led chatbot services in healthcare: A mixed-methods study. Digital Health. 5, p. 205520761987180. https://doi.org/10.1177/2055207619871808

Targeted advertisement of chlamydia screening on social media: A mixed-methods analysis
Nadarzynski, T., Burton, Jack, Henderson, Kimberley, Zimmerman, Deborah, Hill, Orla and Graham, Cynthia 2019. Targeted advertisement of chlamydia screening on social media: A mixed-methods analysis. Digital Health. 5, p. 205520761982719. https://doi.org/10.1177/2055207619827193

Attitudes of pregnant women and healthcare professionals towards clinical trials and routine implementation of antenatal vaccination against respiratory syncytial virus: a multi-centre questionnaire study
Wilcox, Christopher R., Calvert, Anna, Metz, Jane, Kilich, Eliz, MacLeod, Rachael, Beadon, Kirsten, Heath, Paul T, Khalil, Asma, Finn, Adam, Snape, Matthew, Vandrevala, Tushna, Nadarzynski, T., Coleman, Matthew and Jones, Christine 2019. Attitudes of pregnant women and healthcare professionals towards clinical trials and routine implementation of antenatal vaccination against respiratory syncytial virus: a multi-centre questionnaire study. The Pediatric Infectious Disease Journal. 38 (9), pp. 944-951. https://doi.org/10.1097/INF.0000000000002384

Acceptability of artificial intelligence (AI)-led chatbot services in healthcare: A mixed-methods study
Nadarzynski, T., Miles, O., Cowie, A. and Ridge, Damien T. 2019. Acceptability of artificial intelligence (AI)-led chatbot services in healthcare: A mixed-methods study. Digital Health. 5, pp. 1-12. https://doi.org/10.1177/2055207619871808

Determinants of Influenza and Pertussis Vaccination Uptake in Pregnancy: A Multicenter Questionnaire Study of Pregnant Women and Healthcare Professionals
Wilcox, C.R., Calvert, A., Metz, J., Kilich, E., MacLeod, R., Beadon, K, Heath, P.T., Khalil, A., Finn, A., Snape, M.D., Vandrevala, T., Nadarzynski, T., Coleman, M.A. and Jones, C.E. 2019. Determinants of Influenza and Pertussis Vaccination Uptake in Pregnancy: A Multicenter Questionnaire Study of Pregnant Women and Healthcare Professionals. The Pediatric Infectious Disease Journal. 38 (6), pp. 625-630. https://doi.org/10.1097/INF.0000000000002242

Digital Health Psychology
Yardley, L., Bradbury, K., Nadarzynski, T. and Hunter, C. 2019. Digital Health Psychology. in: Revenson, T.A. and Gerung, R.A.R. (ed.) Handbook of Health Psychology New York Routledge. pp. 519-525

Preferences for HIV testing services among men who have sex with men in the UK: A discrete choice experiment
Miners, A., Nadarzynski, T., Witzel, C, Phillips, A.N., Cambiano, V., Rodger, A.J. and Llewellyn, C.D. 2019. Preferences for HIV testing services among men who have sex with men in the UK: A discrete choice experiment. PLoS Medicine. 16 (4) e1002779. https://doi.org/10.1371/journal.pmed.1002779

Mixed-methods study in England and Northern Ireland to understand young men who have sex with men’s knowledge and attitudes towards human papillomavirus vaccination
Kesten, J.M., Flannagan, C., Ruane-McAteer, E., Merriel, S.W.D., Nadarzynski, T., Shapiro, G.K., Rosberger, Z. and Prue, G. 2019. Mixed-methods study in England and Northern Ireland to understand young men who have sex with men’s knowledge and attitudes towards human papillomavirus vaccination. BMJ Open. 9 (e025070) e025070. https://doi.org/10.1136/bmjopen-2018-025070

Determinants of influenza and pertussis vaccination uptake in pregnancy: a multi-centre questionnaire study of pregnant women and healthcare professionals
Wilcox, C.R., Calvert, A., Metz, J., Kilich, E., MacLeod, R., Beadon, K., Heath, P.T., Khalil, A., Finn, A., Snape, M.D., Vandrevala, T., Nadarzynski, T., Coleman, M.A. and Jones, C.E. 2019. Determinants of influenza and pertussis vaccination uptake in pregnancy: a multi-centre questionnaire study of pregnant women and healthcare professionals. The Pediatric Infectious Disease Journal. 38 (6), pp. 625-630. https://doi.org/10.1097/INF.0000000000002242

Attendance of MSM at Genitourinary Medicine services in England: implications for selective HPV vaccination programme (a short communication)
Bayley, J., Mesher, D., Nadarzynski, T., Hughes, G. and Soldan, K. 2018. Attendance of MSM at Genitourinary Medicine services in England: implications for selective HPV vaccination programme (a short communication). Sexually Transmitted Infections. 94, pp. 542-544. https://doi.org/10.1136/sextrans-2016-052912

Men who have sex with men who do not access sexual health clinics nor disclose sexual orientation are unlikely to receive the HPV vaccine in the UK
Nadarzynski, T., Smith, H., Richardson, D., Bremner, S. and Llewellyn, C. 2018. Men who have sex with men who do not access sexual health clinics nor disclose sexual orientation are unlikely to receive the HPV vaccine in the UK. Vaccine. 36 (33), pp. 5065-5070. https://doi.org/10.1016/j.vaccine.2018.06.075

Perceptions of HPV and attitudes towards HPV vaccination amongst men who have sex with men: A qualitative analysis
Nadarzynski, T., Smith, H., Richardson, D., Pollard, A. and Llewellyn, C.D. 2017. Perceptions of HPV and attitudes towards HPV vaccination amongst men who have sex with men: A qualitative analysis. British Journal of Health Psychology. 22 (2), pp. 345-361. https://doi.org/10.1111/bjhp.12233

Sexual healthcare professionals’ views on HPV vaccination for men in the UK
Nadarzynski, T., Smith, H.E., Richardson, D., Ford, E. and Llewellyn, C.D. 2015. Sexual healthcare professionals’ views on HPV vaccination for men in the UK. British Journal of Cancer. 113 (11), pp. 1599-1601. https://doi.org/10.1038/bjc.2015.403

Human papillomavirus and vaccine-related perceptions among men who have sex with men: a systematic review
Nadarzynski, T., Smith, H., Richardson, D., Jones, C.J. and Llewellyn, C.D. 2014. Human papillomavirus and vaccine-related perceptions among men who have sex with men: a systematic review. Sexually Transmitted Infections. 90 (7), pp. 515-523. https://doi.org/10.1136/sextrans-2013-051357

Permalink - https://westminsterresearch.westminster.ac.uk/item/v50w9/vaccine-acceptability-uptake-and-completion-amongst-men-who-have-sex-with-men-a-systematic-review-meta-analysis-and-theoretical-framework


Share this
Tweet
Email

Usage statistics

6 total views
61 total downloads
0 views this month
35 downloads this month
These values are for the period from September 2nd 2018, when this repository was created

Export as