Preprint: Accumulation of prelamin A drives inflammation in the heart with implications for treatment of inherited and acquired cardiomyopathies

Lamin A precursor localizes to the Z-disc of sarcomeres in the heart and is dynamically regulated in muscle cell differentiation
Brayson, D. and Shanahan, C.M. 2022. Lamin A precursor localizes to the Z-disc of sarcomeres in the heart and is dynamically regulated in muscle cell differentiation. Philosophical Transactions of the Royal Society B: Biological Sciences. 377 (1864) 20210490. https://doi.org/10.1098/rstb.2021.0490

The cardio‐respiratory effects of passive heating and the human thermoneutral zone
Henderson, M.E.T., Brayson, D. and Halsey, L.G. 2021. The cardio‐respiratory effects of passive heating and the human thermoneutral zone. Physiological Reports. 9 (16) e14973. https://doi.org/10.14814/phy2.14973

Preprint: Analysis of cardiomyocyte nuclei in human cardiomyopathy reveals orientation dependent defects in shape
Brayson, D., Ehler, E., dos Remedios, C.G. and Shanahan, C.M. 2020. Preprint: Analysis of cardiomyocyte nuclei in human cardiomyopathy reveals orientation dependent defects in shape. medRxiv. https://doi.org/10.1101/2020.08.14.20168310

Right Ventricle Has Normal Myofilament Function But Shows Perturbations in the Expression of Extracellular Matrix Genes in Patients With Tetralogy of Fallot Undergoing Pulmonary Valve Replacement
Brayson, D., Holohan, S-J., Bardswell, S.C., Arno, M., Lu, H., Jensen, H.K., Tran, P.K., Barallobre‐Barreiro, J., Mayr, M., dos Remedios, C.G., Tsang, V.T., Frigiola, A. and Kentish, J.C. 2020. Right Ventricle Has Normal Myofilament Function But Shows Perturbations in the Expression of Extracellular Matrix Genes in Patients With Tetralogy of Fallot Undergoing Pulmonary Valve Replacement. Journal of the American Heart Association. 9 (16) e015342. https://doi.org/10.1161/jaha.119.015342

The nuclear envelope: LINCing tissue mechanics to genome regulation in cardiac and skeletal muscle
Piccus, R. and Brayson, D. 2020. The nuclear envelope: LINCing tissue mechanics to genome regulation in cardiac and skeletal muscle. Biology Letters. 16 (7) 20200302. https://doi.org/10.1098/rsbl.2020.0302

Prelamin A mediates myocardial inflammation in dilated and HIV-associated cardiomyopathies
Brayson, D., Frustaci, A., Verardo, R., Chimenti, C., Russo, M.A., Hayward, R., Ahmad, S.M., Vizcay-Barrena, G., Protti, A., Zammit, P.S., dos Remedios, C.G., Ehler, E., Shah, A.M. and Shanahan, C.M. 2019. Prelamin A mediates myocardial inflammation in dilated and HIV-associated cardiomyopathies. JCI Insight. 4 (22) e126315. https://doi.org/10.1172/jci.insight.126315

Dynamic heart rate response to multi-day unsupported ultra-endurance cycle racing: a case report
Daniel Brayson, Alessandra Frigiola and James E. Clark 2019. Dynamic heart rate response to multi-day unsupported ultra-endurance cycle racing: a case report. Experimental Physiology. 104 (2), pp. 174-179. https://doi.org/10.1113/ep087341

Muscle tensions merge to cause a DNA replication crisis.
Brayson, D., Ho, C.Y. and Shanahan, C.M. 2018. Muscle tensions merge to cause a DNA replication crisis. The Journal of Cell biology. 217 (6), pp. 1891-1893. https://doi.org/10.1083/jcb.201804041

Current insights into LMNA cardiomyopathies: Existing models and missing LINCs.
Brayson, D. and Shanahan, C.M. 2017. Current insights into LMNA cardiomyopathies: Existing models and missing LINCs. Nucleus. 8 (1), pp. 17-33. https://doi.org/10.1080/19491034.2016.1260798

Rnd3 induces stress fibres in endothelial cells through RhoB.
Gottesbühren, U., Garg, R., Riou, P., McColl, B., Brayson, D. and Ridley, A.J. 2013. Rnd3 induces stress fibres in endothelial cells through RhoB. Biology Open. 2 (2), pp. 210-216. https://doi.org/10.1242/bio.20123574