Muscle tensions merge to cause a DNA replication crisis.

Preprint: Resilience to cardiac aging in Greenland shark Somniosus microcephalus
Elena Chiavacci, Kirstine Fleng Steffensen, Pierre Delaroche, Emanuele Astoricchio, Amalie Bech Poulsen, Daniel Brayson, Fulvio Garibaldi, Luca Lanteri, Christian Pinali, Giovanni Roppo Valente, Federico Vignati, John Fleng Steffensen, Holly Shiels, Eva Terzibasi Tozzini and Alessandro Cellerino 2025. Preprint: Resilience to cardiac aging in Greenland shark Somniosus microcephalus. biorxiv.org. https://doi.org/10.64898/2025.12.20.695706

Ferric derisomaltose augments intrinsic skeletal muscle electron transport chain activity in heart failure: A FERRIC-HF II molecular substudy
Barakat, M.F., Amaral, N., Brayson, D., Amin-Youssef, G., Abu-Own, H., Ayis, S., Papalia, F., Jouhra, F., Nabeebaccus, A., Monaghan, M., Carr-White, G., Sleigh, A., Charles-Edwards, G., Shah, A.M., Kemp, G.J., Murray, A.J. and Okonko, D.O. 2025. Ferric derisomaltose augments intrinsic skeletal muscle electron transport chain activity in heart failure: A FERRIC-HF II molecular substudy. European Journal of Heart Failure. 27 (11), pp. 2343-2351. https://doi.org/10.1002/ejhf.70028

Attenuated maximum heart rate following ultra endurance cycling and the role of the autonomic nervous system: An exploratory study.
Ajayi, S., Mattin, L.R., Gaze, D.C. and Brayson, D. 2025. Attenuated maximum heart rate following ultra endurance cycling and the role of the autonomic nervous system: An exploratory study. 40th Congress of the International Union of Physiological Sciences. Frankfurt, Germany 11 - 14 Sep 2025 The Physiological Society.

Investigating heart rate regulation in ultra-endurance cyclists: A pilot study
Ajayi, S., Mattin, L.R., Gaze, D.C. and Brayson, D. 2025. Investigating heart rate regulation in ultra-endurance cyclists: A pilot study. 40th Congress of the International Union of Physiological Sciences. Frankfurt, Germany 11 - 14 Sep 2025 The Physiological Society.

Lamin A precursor localizes to the Z-disc of sarcomeres in the heart and is dynamically regulated in muscle cell differentiation
Brayson, D. and Shanahan, C.M. 2022. Lamin A precursor localizes to the Z-disc of sarcomeres in the heart and is dynamically regulated in muscle cell differentiation. Philosophical Transactions of the Royal Society B: Biological Sciences. 377 (1864) 20210490. https://doi.org/10.1098/rstb.2021.0490

The cardio‐respiratory effects of passive heating and the human thermoneutral zone
Henderson, M.E.T., Brayson, D. and Halsey, L.G. 2021. The cardio‐respiratory effects of passive heating and the human thermoneutral zone. Physiological Reports. 9 (16) e14973. https://doi.org/10.14814/phy2.14973

Preprint: Analysis of cardiomyocyte nuclei in human cardiomyopathy reveals orientation dependent defects in shape
Brayson, D., Ehler, E., dos Remedios, C.G. and Shanahan, C.M. 2020. Preprint: Analysis of cardiomyocyte nuclei in human cardiomyopathy reveals orientation dependent defects in shape. medRxiv. https://doi.org/10.1101/2020.08.14.20168310

Right Ventricle Has Normal Myofilament Function But Shows Perturbations in the Expression of Extracellular Matrix Genes in Patients With Tetralogy of Fallot Undergoing Pulmonary Valve Replacement
Brayson, D., Holohan, S-J., Bardswell, S.C., Arno, M., Lu, H., Jensen, H.K., Tran, P.K., Barallobre‐Barreiro, J., Mayr, M., dos Remedios, C.G., Tsang, V.T., Frigiola, A. and Kentish, J.C. 2020. Right Ventricle Has Normal Myofilament Function But Shows Perturbations in the Expression of Extracellular Matrix Genes in Patients With Tetralogy of Fallot Undergoing Pulmonary Valve Replacement. Journal of the American Heart Association. 9 (16) e015342. https://doi.org/10.1161/jaha.119.015342

The nuclear envelope: LINCing tissue mechanics to genome regulation in cardiac and skeletal muscle
Piccus, R. and Brayson, D. 2020. The nuclear envelope: LINCing tissue mechanics to genome regulation in cardiac and skeletal muscle. Biology Letters. 16 (7) 20200302. https://doi.org/10.1098/rsbl.2020.0302

Prelamin A mediates myocardial inflammation in dilated and HIV-associated cardiomyopathies
Brayson, D., Frustaci, A., Verardo, R., Chimenti, C., Russo, M.A., Hayward, R., Ahmad, S.M., Vizcay-Barrena, G., Protti, A., Zammit, P.S., dos Remedios, C.G., Ehler, E., Shah, A.M. and Shanahan, C.M. 2019. Prelamin A mediates myocardial inflammation in dilated and HIV-associated cardiomyopathies. JCI Insight. 4 (22) e126315. https://doi.org/10.1172/jci.insight.126315

Dynamic heart rate response to multi-day unsupported ultra-endurance cycle racing: a case report
Daniel Brayson, Alessandra Frigiola and James E. Clark 2019. Dynamic heart rate response to multi-day unsupported ultra-endurance cycle racing: a case report. Experimental Physiology. 104 (2), pp. 174-179. https://doi.org/10.1113/ep087341

Preprint: Accumulation of prelamin A drives inflammation in the heart with implications for treatment of inherited and acquired cardiomyopathies
Daniel Brayson, Andrea Frustaci, Romina Verardo, Cristina Chimenti, Matteo Antonio Russo, Robert Hayward, Sadia Munir Ahmad, Gema Vizcay-Barrena, Andrea Protti, Peter S. Zammit, Cristobal G. dos Remedios, Elisabeth Ehler, Ajay M. Shah and Catherine M. Shanahan 2018. Preprint: Accumulation of prelamin A drives inflammation in the heart with implications for treatment of inherited and acquired cardiomyopathies. biorxiv.org. https://doi.org/10.1101/457044

Current insights into LMNA cardiomyopathies: Existing models and missing LINCs.
Brayson, D. and Shanahan, C.M. 2017. Current insights into LMNA cardiomyopathies: Existing models and missing LINCs. Nucleus. 8 (1), pp. 17-33. https://doi.org/10.1080/19491034.2016.1260798

Rnd3 induces stress fibres in endothelial cells through RhoB.
Gottesbühren, U., Garg, R., Riou, P., McColl, B., Brayson, D. and Ridley, A.J. 2013. Rnd3 induces stress fibres in endothelial cells through RhoB. Biology Open. 2 (2), pp. 210-216. https://doi.org/10.1242/bio.20123574