Title | Prognostic performance of pretreatment systemic immune-inflammation index in women with epithelial ovarian cancer |
---|
Type | Journal article |
---|
Authors | Kehinde S. Okunade, Sarah O. John-Olabode, Adaiah P. Soibi-Harry, Austin C. Okoro, Adebola A. Adejimi, Iyabo Y. Ademuyiwa, Benedetto Osunwusi, Hameed Adelabu and Omolola Salako |
---|
Abstract | Purpose: This study investigated the prognostic performance of the systemic immune-inflammation index (SII) in patients with epithelial ovarian cancer (EOC) in Lagos, Nigeria. Methods: We performed a secondary analysis of the data of 91 women who had treatment for EOC between 2009 and 2018. The associations between pretreatment SII and survivals were tested. Results: Pretreatment SII more than 610.2 was a significant independent predictor of reduced progression-free survival (HR = 2.68; 95% CI, 1.17 to 6.09) while SII greater than 649.0 was a significant independent predictor of reduced 3-year overall survival (HR = 2.01; 95% CI, 1.01 to 3.99). Conclusion: These findings suggest that high SII may be a potential prognostic indicator and useful marker for more intensive surveillance and design of personalized treatment in patients with EOC. |
---|
Article number | FSO897 |
---|
Journal | Future Science OA |
---|
Journal citation | 9 (10) |
---|
ISSN | 2056-5623 |
---|
Year | 2023 |
---|
Publisher | Future Science |
---|
Publisher's version | License CC BY 4.0 File Access Level Open (open metadata and files) |
---|
Digital Object Identifier (DOI) | https://doi.org/10.2144/fsoa-2023-0108 |
---|
Web address (URL) | https://doi.org/10.2144/fsoa-2023-0108 |
---|
Publication dates |
---|
Published in print | Dec 2023 |
---|
Published online | 28 Aug 2023 |
---|