Sulforaphane alters cerebral leukocyte endothelial cell interactions post global ischaemia reperfusion

Late changes in blood-brain barrier permeability in a rat tMCAO model of stroke detected by gadolinium-enhanced MRI
Morgan, C.A., Mesquita, M., Ashioti, M., Beech, J.S., Williams, S.C.R., Irving, E. and Cash, D. 2020. Late changes in blood-brain barrier permeability in a rat tMCAO model of stroke detected by gadolinium-enhanced MRI. Neurological Research. 42 (10), pp. 844-852. https://doi.org/10.1080/01616412.2020.1786637

Polymorphism of amyloid fibrils and their complexes with catalase
Milton, N.G.N. and Harris, J.R. 2014. Polymorphism of amyloid fibrils and their complexes with catalase. in: Uversky, V.N. and Lyubchenko, Y.L. (ed.) Bio-nanoimaging: protein misfolding and aggregation Boston Academic Press. pp. 255-262

Immunocytochemical staining of endogenous nuclear proteins with the HIS-1 anti-poly-histidine monoclonal antibody: a potential source of error in His-tagged protein detection
Chilumuri, A., Markiv, A. and Milton, N.G.N. 2014. Immunocytochemical staining of endogenous nuclear proteins with the HIS-1 anti-poly-histidine monoclonal antibody: a potential source of error in His-tagged protein detection. Acta Histochemica. 116 (6), pp. 1022-1028. https://doi.org/10.1016/j.acthis.2014.04.006

The neuroprotective role of catalase overexpression in SH-SY5Y cells against beta-amyloid and H2O2 toxicity
Chilumuri, A., Odell, M. and Milton, N.G.N. 2013. The neuroprotective role of catalase overexpression in SH-SY5Y cells against beta-amyloid and H2O2 toxicity. Alzheimer's & Dementia. 9 (4), p. P361.

Kissorphin peptides for use in the treatment of Alzheimer's disease, Creutzfeldt-Jakob disease or diabetes mellitus
Milton, N.G.N. 2013. Kissorphin peptides for use in the treatment of Alzheimer's disease, Creutzfeldt-Jakob disease or diabetes mellitus.

Benzothiazole aniline-tetra(ethylene glycol) and 3-amino-1,2,4-triazole inhibit neuroprotection against amyloid peptides by catalase overexpression in vitro
Chilumuri, A., Odell, M. and Milton, N.G.N. 2013. Benzothiazole aniline-tetra(ethylene glycol) and 3-amino-1,2,4-triazole inhibit neuroprotection against amyloid peptides by catalase overexpression in vitro. ACS chemical neuroscience. 4 (11), pp. 1501-1512. https://doi.org/10.1021/cn400146a

The role of neurotransmitters in protection against amyloid-β toxicity by KiSS-1 overexpression in SH-SY5Y neurons
Chilumuri, A. and Milton, N.G.N. 2013. The role of neurotransmitters in protection against amyloid-β toxicity by KiSS-1 overexpression in SH-SY5Y neurons. ISRN Neuroscience. 2013 253210. https://doi.org/10.1155/2013/253210

Immunolocalization of kisspeptin associated with amyloid-β deposits in the pons of an Alzheimer’s disease patient
Chilumuri, A., Ashioti, M., Nercessian, A.N. and Milton, N.G.N. 2013. Immunolocalization of kisspeptin associated with amyloid-β deposits in the pons of an Alzheimer’s disease patient. Journal of Neurodegenerative Diseases. 2013 879710. https://doi.org/10.1155/2013/879710

Neuroprotective efficacy of the endogenous neuropeptide Urocortin in a oxygen-glucose deprivation model of transient cerebral ischaemia with reperfusion
Ashioti, M., Getting, S.J., Locke, I.C. and Milton, N.G.N. 2013. Neuroprotective efficacy of the endogenous neuropeptide Urocortin in a oxygen-glucose deprivation model of transient cerebral ischaemia with reperfusion. British Neuroscience Association 22nd Biennial Meeting. London 7th-10th April 2013

Fibril formation and toxicity of the non-amyloidogenic rat amylin peptide
Milton, N.G.N. and Harris, J.R. 2013. Fibril formation and toxicity of the non-amyloidogenic rat amylin peptide. Micron. 44, pp. 246-253. https://doi.org/10.1016/j.micron.2012.07.001

Kisspeptin prevention of Amyloid-β Peptide neurotoxicity in vitro
Milton, N.G.N., Chilumuri, A., Rocha-Ferreira, E., Nercessian, A.N. and Ashioti, M. 2012. Kisspeptin prevention of Amyloid-β Peptide neurotoxicity in vitro. ACS chemical neuroscience. 3 (9), pp. 706-719. https://doi.org/10.1021/cn300045d

Kissorphin, a hexapeptide derivative of Kisspeptin, acts via Neuropeptide FF receptors to inhibit cyclic adenosine monophosphate release but has no Gonadotrophin-Releasing-Hormone releasing activity
Milton, N.G.N. 2012. Kissorphin, a hexapeptide derivative of Kisspeptin, acts via Neuropeptide FF receptors to inhibit cyclic adenosine monophosphate release but has no Gonadotrophin-Releasing-Hormone releasing activity. Endocrine Abstracts. 28, p. OC2.3.

In vitro activities of Kissorphin, a novel hexapeptide KiSS-1 derivative, in neuronal cells
Milton, N.G.N. 2012. In vitro activities of Kissorphin, a novel hexapeptide KiSS-1 derivative, in neuronal cells. Journal of Amino Acids. 2012 691463. https://doi.org/10.1155/2012/691463

Introduction and technical survey: protein aggregation and fibrillogenesis
Harris, J.R. and Milton, N.G.N. 2012. Introduction and technical survey: protein aggregation and fibrillogenesis. Subcellular Biochemistry. 65, pp. 3-25. https://doi.org/10.1007/978-94-007-5416-4_1

Leukocyte recruitment in the brain in sepsis: involvement of the annexin 1-FPR2/ALX anti-inflammatory system
Gavins, F.N.E., Hughes, E.L., Buss, N.A.P.S., Holloway, P.M., Getting, S.J. and Buckingham, J.C. 2012. Leukocyte recruitment in the brain in sepsis: involvement of the annexin 1-FPR2/ALX anti-inflammatory system. FASEB Journal. 26 (12), pp. 4977-4989. https://doi.org/10.1096/fj.12-205971

The Melanocortin receptor system as an anti-inflammatory therapeutic target for stroke
Holloway, P.M., Getting, S.J. and Gavins, F.N.E. 2011. The Melanocortin receptor system as an anti-inflammatory therapeutic target for stroke. pA2 online, E-journal of the British Pharmacological Society.

Investigating the role of melanocortin receptor subtypes in mediating anti-inflammatory protection following cerebral ischemia reperfusion injury
Holloway, P.M., Getting, S.J. and Gavins, F.N.E. 2011. Investigating the role of melanocortin receptor subtypes in mediating anti-inflammatory protection following cerebral ischemia reperfusion injury. pA2 online, E-journal of the British Pharmacological Society.

Targeting the melanocortin receptor system for anti-stroke therapy
Holloway, P.M., Smith, H.K., Renshaw, D., Flower, R.J., Getting, S.J. and Gavins, F.N.E. 2011. Targeting the melanocortin receptor system for anti-stroke therapy. Trends in Pharmacological Sciences. 32 (2), pp. 90-98. https://doi.org/10.1016/j.tips.2010.11.010

Kissorphin Peptides used in the treatment of Alzheimer’s Disease, Creutzfeldt Jakob Disease or Diabetes Mellitus P.
Milton, N.G.N. 2011. Kissorphin Peptides used in the treatment of Alzheimer’s Disease, Creutzfeldt Jakob Disease or Diabetes Mellitus P.

Kissorphin Peptides used in the treatment of Alzheimer’s Disease, Creutzfeldt Jakob Disease or Diabetes Mellitus P.
Milton, N.G.N. 2011. Kissorphin Peptides used in the treatment of Alzheimer’s Disease, Creutzfeldt Jakob Disease or Diabetes Mellitus P.

Human islet amyloid polypeptide fibril binding to catalase: a transmission electron microscopy and microplate study
Milton, N.G.N. and Harris, J.R. 2010. Human islet amyloid polypeptide fibril binding to catalase: a transmission electron microscopy and microplate study. ScientificWorldJournal. 10, pp. 879-893. https://doi.org/10.1100/tsw.2010.73

Cholesterol in Alzheimer's disease and other amyloidogenic disorders
Harris, J.R. and Milton, N.G.N. 2010. Cholesterol in Alzheimer's disease and other amyloidogenic disorders. Subcellular Biochemistry. 51, pp. 47-75. https://doi.org/10.1007/978-90-481-8622-8_2

Polymorphism of amyloid-ß fibrils and its effects on human erythrocyte catalase binding
Milton, N.G.N. and Harris, J.R. 2009. Polymorphism of amyloid-ß fibrils and its effects on human erythrocyte catalase binding. Micron. 40 (8), pp. 800-810. https://doi.org/10.1016/j.micron.2009.07.006

Neither in vivo MRI nor behavioural assessment indicate therapeutic efficacy for a novel 5HT1A agonist in rat models of ischaemic stroke
Ashioti, M., Beech, J.S., Lowe, A.S., Bernanos, M., McCreary, A., Modo, M.M. and Williams, S.C.R. 2009. Neither in vivo MRI nor behavioural assessment indicate therapeutic efficacy for a novel 5HT1A agonist in rat models of ischaemic stroke. BMC Neuroscience. 10 (82). https://doi.org/10.1186/1471-2202-10-82

Inflamed phenotype of the mesenteric microcirculation of melanocortin type 3 receptor-null mice after ischemia-reperfusion
Leoni, G., Patel, H.B., Sampaio, A.L.F., Gavins, F.N.E., Murray, J.F., Grieco, P., Getting, S.J. and Perretti, M. 2008. Inflamed phenotype of the mesenteric microcirculation of melanocortin type 3 receptor-null mice after ischemia-reperfusion. FASEB Journal. 22 (12), pp. 4228-4238. https://doi.org/10.1096/fj.08-113886

Annexin A1 in the brain: undiscovered roles?
Solito, E., McArthur, S., Christian, H.C., Gavins, F.N.E., Buckingham, J.C. and Gillies, G.E. 2008. Annexin A1 in the brain: undiscovered roles? Trends in Pharmacological Sciences. 29 (3), pp. 135-42. https://doi.org/10.1016/j.tips.2007.12.003

Homocysteine inhibits hydrogen peroxide breakdown by catalase
Milton, N.G.N. 2008. Homocysteine inhibits hydrogen peroxide breakdown by catalase. Open Enzyme Inhibition Journal. 1, pp. 34-41. https://doi.org/10.2174/1874940200801010034

Tonic inhibitory control of the mesenteric microcirculation by the melanocortin type 3 receptor
Leoni, G., Patel, H.B., Sampaio, A.L.F., Gavins, F.N.E., Getting, S.J. and Perretti, M. 2008. Tonic inhibitory control of the mesenteric microcirculation by the melanocortin type 3 receptor. Journal of Vascular Research. 45 (Suppl2).

Inhibitory role of endogenous melanocortin type 3 receptor in the inflamed microcirculation
Leoni, G., Patel, H.B., Sampaio, A.L.F., Gavins, F.N.E., Getting, S.J. and Perretti, M. 2008. Inhibitory role of endogenous melanocortin type 3 receptor in the inflamed microcirculation. William Harvey Day. St. Barts Hospital, London 14th October 2008

Crucial role for endogenous melanocortin type 3 receptor in mesenteric post-reperfusion injury. PC106
Leoni, G., Getting, S.J., Gavins, F.N.E. and Perretti, M. 2007. Crucial role for endogenous melanocortin type 3 receptor in mesenteric post-reperfusion injury. PC106. Life Sciences. Glasgow 8th - 12th July 2007

[D -Trp8]-γ -melanocyte -stimulating hormone exhibits anti-inflammatory efficacy in mice bearing a nonfunctional MC1 R(Recessive Yellow e/e Mouse)
Getting, S.J., Lam, C.W., Leoni, G., Gavins, F.N.E., Grieco, P. and Perretti, M. 2006. [D -Trp8]-γ -melanocyte -stimulating hormone exhibits anti-inflammatory efficacy in mice bearing a nonfunctional MC1 R(Recessive Yellow e/e Mouse). Molecular Pharmacology. 70 (6), pp. 1850-1855. https://doi.org/10.1124/mol.106.028878

Annexin 1 and melanocortin peptide therapy for protection against ischaemic-reperfusion damage in the heart
Gavins, F.N.E., Leoni, G. and Getting, S.J. 2006. Annexin 1 and melanocortin peptide therapy for protection against ischaemic-reperfusion damage in the heart. ScientificWorldJournal. 6, pp. 1008-1023. https://doi.org/10.1100/tsw.2006.196

Interactions between amyloid-ß and enzymes
Milton, N.G.N. 2006. Interactions between amyloid-ß and enzymes. in: Harris, J.R., Graham, J. and Rickwood, D. (ed.) Cell biology protocols Chichester Wiley. pp. 359-363

Anti-sense peptides
Milton, N.G.N. 2006. Anti-sense peptides. in: Harris, J.R., Graham, J. and Rickwood, D. (ed.) Cell biology protocols Chichester Wiley. pp. 353-358

Amyloid-ß phosphorylation
Milton, N.G.N. 2006. Amyloid-ß phosphorylation. in: Harris, J.R., Graham, J. and Rickwood, D. (ed.) Cell biology protocols Chichester Wiley. pp. 364-368

Phosphorylated Amyloid-ß 1-43 protein and its use in the treatment of Alzheimer's disease
Milton, N.G.N. 2005. Phosphorylated Amyloid-ß 1-43 protein and its use in the treatment of Alzheimer's disease.

Phosphorylated amyloid-ß: the toxic intermediate in Alzheimer's disease neurodegeneration
Milton, N.G.N. 2005. Phosphorylated amyloid-ß: the toxic intermediate in Alzheimer's disease neurodegeneration. Subcellular Biochemistry. 38, pp. 381-402.

Peptides for use in the treatment of Alzheimer's disease
Milton, N.G.N. 2004. Peptides for use in the treatment of Alzheimer's disease.

The annexin 1-/- mouse: phenotypic studies
Wells, D., Wells, K., Liu, K., Hannon, R., Croxtall, J.D., Damazo, A.S., Oliani, S.M., Getting, S.J., Parente, L., Paul-Clark, M., Yona, S., Gavins, F.N.E., Martin, J., Christian, H.C., Cover, P.O., John, C.D., Solito, E., Morris, J.F., Perretti, M., Buckingham, J.C. and Flower, R.J. 2004. The annexin 1-/- mouse: phenotypic studies. Annexins. 1 (2), pp. 109-120.

Role of hydrogen peroxide in the aetiology of Alzheimer's disease: implications for treatment
Milton, N.G.N. 2004. Role of hydrogen peroxide in the aetiology of Alzheimer's disease: implications for treatment. Drugs & Aging. 21 (2), pp. 81-100.

Redundancy of a Functional Melanocortin 1 Receptor in the Anti-inflammatory actions of melanocortin peptides: studies in the recessive yellow (e/e) mouse suggest an important role for melanocortin 3 receptor
Getting, S.J., Christian, H.C., Lam, C.W., Gavins, F.N.E., Flower, R.J., Schiöth, H.B. and Perretti, M. 2003. Redundancy of a Functional Melanocortin 1 Receptor in the Anti-inflammatory actions of melanocortin peptides: studies in the recessive yellow (e/e) mouse suggest an important role for melanocortin 3 receptor. Journal of Immunology. 170 (6), pp. 3323-3330.

Peptides for use in the treatment of Alzheimer's disease
Milton, N.G.N. 2003. Peptides for use in the treatment of Alzheimer's disease.

Aberrant inflammation and resistance to glucocorticoids in annexin 1-/- mouse
Hannon, R., Croxtall, J.D., Getting, S.J., Roviezzo, F., Yona, S., Paul-Clark, M., Gavins, F.N.E., Perretti, M., Morris, J.F., Buckingham, J.C. and Flower, R.J. 2003. Aberrant inflammation and resistance to glucocorticoids in annexin 1-/- mouse. FASEB Journal. 17 (2), pp. 253-255. https://doi.org/10.1096/fj.02-0239fje

The annexin-1 knockout mouse: what it tells us about the inflammatory response
Roviezzo, F., Getting, S.J., Paul-Clark, M., Yona, S., Gavins, F.N.E., Perretti, M., Hannon, R., Croxtall, J.D., Buckingham, J.C. and Flower, R.J. 2002. The annexin-1 knockout mouse: what it tells us about the inflammatory response. Journal of Physiology and Pharmacology. 53 (4, part 1), pp. 541 -553.

Anandamide and noladin ether prevent neurotoxicity of the human amyloid-ß peptide
Milton, N.G.N. 2002. Anandamide and noladin ether prevent neurotoxicity of the human amyloid-ß peptide. Neuroscience Letters. 332 (2), pp. 127-130. https://doi.org/10.1016/S0304-3940(02)00936-9

The amyloid-β peptide binds to cyclin B1 and increases human cyclin-dependent kinase-1 activity
Milton, N.G.N. 2002. The amyloid-β peptide binds to cyclin B1 and increases human cyclin-dependent kinase-1 activity. Neuroscience Letters. 322 (2), pp. 131-133. https://doi.org/10.1016/S0304-3940(02)00081-2

Lipoprotein (a) does not participate in the early acute phase response to training or extreme physical activity and is unlikely to enhance any associated immediate cardiovascular risk
Byrne, D.J., Jagroop, I.A., Montgomery, H., Thomas, M., Mikhailidis, D.P., Milton, N.G.N. and Winder, A.F. 2002. Lipoprotein (a) does not participate in the early acute phase response to training or extreme physical activity and is unlikely to enhance any associated immediate cardiovascular risk. Journal of Clinical Pathology. 55 (4), pp. 280-285.

Peptides for use in the treatment of Alzheimer's disease
Milton, N.G.N. 2002. Peptides for use in the treatment of Alzheimer's disease.

Phosphorylation of amyloid-ß at the serine 26 residue by human cdc2 kinase
Milton, N.G.N. 2001. Phosphorylation of amyloid-ß at the serine 26 residue by human cdc2 kinase. NeuroReport. 12 (17), pp. 3839-3844.

Inhibition of catalase activity with 3-amino-triazole enhances the cytotoxicity of the Alzheimer’s amyloid-ß peptide
Milton, N.G.N. 2001. Inhibition of catalase activity with 3-amino-triazole enhances the cytotoxicity of the Alzheimer’s amyloid-ß peptide. NeuroToxicology. 72 (6), pp. 767-774. https://doi.org/10.1016/S0161-813X(01)00064-X

Identification of amyloid-ß binding sites using an antisense peptide approach
Milton, N.G.N., Mayor, N.P. and Rawlinson, J. 2001. Identification of amyloid-ß binding sites using an antisense peptide approach. NeuroReport. 12 (11), pp. 2561-2566.