Recommended aerobic fitness level for metabolic health in children and adolescents: a study of diagnostic accuracy

Adegboye, A.R., Anderssen, S.A., Froberg, K., Sardinha, L.B., Heitmann, B.L., Steene-Johannessen, J., Kolle, E. and Andersen, L.B. 2011. Recommended aerobic fitness level for metabolic health in children and adolescents: a study of diagnostic accuracy. British Journal of Sports Medicine. 45 (9), pp. 722-728. doi:10.1136/bjsm.2009.068346

TitleRecommended aerobic fitness level for metabolic health in children and adolescents: a study of diagnostic accuracy
AuthorsAdegboye, A.R., Anderssen, S.A., Froberg, K., Sardinha, L.B., Heitmann, B.L., Steene-Johannessen, J., Kolle, E. and Andersen, L.B.
Abstract

Objective: To define the optimal cut-off for low aerobic fitness and to evaluate its accuracy to predict clustering of risk factors for cardiovascular disease in children and adolescents.
Design: Study of diagnostic accuracy using a cross-sectional database.
Setting: European Youth Heart Study including Denmark, Portugal, Estonia and Norway.
Participants: 4500 schoolchildren aged 9 or 15 years.
Main Outcome: Measure Aerobic fitness was expressed as peak oxygen consumption relative to bodyweight (mlO2/min/kg).
Results: Risk factors included in the composite risk score (mean of z-scores) were systolic blood pressure, triglyceride, total cholesterol/HDL-cholesterol ratio, insulin resistance and sum of four skinfolds. 14.5% of the sample, with a risk score above one SD, were defined as being at risk. Receiver operating characteristic analysis was used to define the optimal cut-off for sex and age-specific distribution. In girls, the optimal cut-offs for identifying individuals at risk were: 37.4 mlO2/min/kg (9-year-old) and 33.0 mlO2/min/kg (15-year-old). In boys, the optimal cut-offs were 43.6 mlO2/min/kg (9-year-old) and 46.0 mlO2/min/kg (15-year-old). Specificity (range 79.3–86.4%) was markedly higher than sensitivity (range 29.7–55.6%) for all cut-offs. Positive predictive values ranged from 19% to 41% and negative predictive values ranged from 88% to 90%. The diagnostic accuracy for identifying children at risk, measured by the area under the curve (AUC), was significantly higher than what would be expected by chance (AUC >0.5) for all cut-offs.
Conclusions: Aerobic fitness is easy to measure, and is an accurate tool for screening children with clustering of cardiovascular risk factors. Promoting physical activity in children with aerobic fitness level lower than the suggested cut-points might improve their health.

JournalBritish Journal of Sports Medicine
Journal citation45 (9), pp. 722-728
ISSN0306-3674
Year2011
PublisherBritish Association of Sport and Exercise Medicine
Digital Object Identifier (DOI)doi:10.1136/bjsm.2009.068346
Publication dates
Published17 Jun 2010

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