|Title||Development of bio-composites with novel characteristics through enzymatic grafting|
Enzymatic grafting of biopolymers has recently been the focus of green chemistry technologies due to the growing environmental concerns, and subsequent legal
In this context, a series of bio-composites e.g. poly3-hydroxybutyrate [P(3HB)]grafted ethyl cellulose (EC) and bacterial cellulose (BC) [i.e., P(3HB)-g-EC/BC] and
This project shows improvement in the thermo-mechanical properties of the biocomposites as compared to the individual components. The tensile strength, elongation
The phenol grafted bio-composites were critically evaluated for their antibacterial and biocompatibility features, as well as their degradability in a soil. In particular, the results of the antibacterial evaluation indicated that 20CA-g-P(3HB)-EC, 15GA-g-P(3HB)-EC, 15HBA-g-P(3HB)-EC, 15T-g-P(3HB)-EC, 15CA-g-keratin-EC, 15GAg-keratin-EC, 10HBA-g-keratin-EC and 20T-g-keratin-EC exerted strong bactericidal and bacteriostatic activity against Gram+ bacteria Bacillus subtilis NCTC 3610 and Staphylococcus aureus NCTC 6571 and Gram- bacteria Escherichia coli NCTC 10418 and Pseudomonas aeruginosa NCTC 10662 strains, respectively. This study shows further that at various phenolic concentrations the newly synthesised bio-composites remained cytocompatible with human keratinocyte-like HaCaT skin cells, as 100% cell
This study provides novel and additional knowledge that encourage greater utilisation of biopolymers in the development of bio-composites with novel and sophisticated characteristics for potential applications.
|Accepted author manuscript||Iqbal_Hafiz_thesis.pdf|