PUFA stabilizes a conductive state of the selectivity filter in IKs channels Alessia Golluscio, Jodene Eldstrom, Jessica J. Jowais, Marta Elena Perez, Kevin Peter Cunningham, Alicia De La Cruz, Xiaoan Wu, Valentina Corradi, D. Peter Tieleman, David Fedida and H. Peter Larsson 2024. PUFA stabilizes a conductive state of the selectivity filter in IKs channels. eLife. 13 RP95852. https://doi.org/10.7554/elife.95852
2024
Propofol rescues voltage-dependent gating of HCN1 channel epilepsy mutants Elizabeth D. Kim, Xiaoan Wu, Sangyun Lee, Gareth R. Tibbs, Kevin P. Cunningham, Eleonora Di Zanni, Marta E. Perez, Peter A. Goldstein, Alessio Accardi, H. Peter Larsson and Crina M. Nimigean 2024. Propofol rescues voltage-dependent gating of HCN1 channel epilepsy mutants. Nature. 632, pp. 451-459. https://doi.org/10.1038/s41586-024-07743-z
Artemisinin inhibits neutrophil and macrophage chemotaxis, cytokine production and NET release Morad, H.O.J., Luqman, S., Garcia Pinto, L., Cunningham, K., Vilar, B., Clayton, G., Shankar-Hari, M. and McNaughton, P.A. 2022. Artemisinin inhibits neutrophil and macrophage chemotaxis, cytokine production and NET release. Scientific Reports. 2022 (12) 11078. https://doi.org/10.1038/s41598-022-15214-6
Two-Pore Domain Potassium Channels as Drug Targets: Anesthesia and Beyond. Mathie, A., Veale, E.L., Cunningham, K.P., Holden, R.G. and Wright, P.D. 2021. Two-Pore Domain Potassium Channels as Drug Targets: Anesthesia and Beyond. Annual Review of Pharmacology and Toxicology. 61, pp. 401-420. https://doi.org/10.1146/annurev-pharmtox-030920-111536
Preprint: Binding of PUFA stabilizes a conductive state of the selectivity filter in IKs channels Alessia Golluscio, Jodene Eldstrom, Jessica J. Jowais, Marta E. Perez-Rodriguez, Kevin P. Cunningham, Alicia de la Cruz, Xiaoan Wu, David Fedida and H. Peter Larsson 2024. Preprint: Binding of PUFA stabilizes a conductive state of the selectivity filter in IKs channels. arXiv. https://doi.org/10.1101/2024.01.11.575247
