Abrus Toxins: Study on a dangerous lectin duo present in the seeds of Indian licorice

Surendranath, K. 2009. Abrus Toxins: Study on a dangerous lectin duo present in the seeds of Indian licorice. Germany Lambert Academic Publishing GmbH & Company KG.

Title Abrus Toxins: Study on a dangerous lectin duo present in the seeds of Indian licorice
AuthorsSurendranath, K.
Abstract

Abrin and Abrus Agglutinin are natural toxins found in the seeds of the sub tropical climber Abrus precatorius. Both are proteins that are stable at extreme conditions and could be fatal to health when ingested. The dreadful nature of them could be judged by the fact that a single well-masticated seed is capable of killing an adult. The toxins work by getting inside the cells of a person s body and prevent the cells from making proteins, the building blocks of the cell. Eventually cell death occurs resulting in the seizure of the whole body. No anecdote exists for these toxins and symptoms of poisoning may differ depending on the route of exposure

KeywordsAbrus precatorius
Year2009
PublisherLambert Academic Publishing GmbH & Company KG
Publication dates
Published11 Nov 2009
Place of publicationGermany
ISBN9783838307923

Related outputs

RECQ5 Helicase Cooperates with MUS81 Endonuclease in Processing Stalled Replication Forks at Common Fragile Sites during Mitosis
Di Marco, S., Hasanova, Z., Kanagaraj, R., Chappidi, N., Altmannova, V., Menon, S., Sedlackova, H., Langhoff, J., Surendranath, K., Hühn, D., Bhowmick, R., Marini, V., Ferrari, S., Hickson, I.D., Krejci, L. and Janscak, P. 2017. RECQ5 Helicase Cooperates with MUS81 Endonuclease in Processing Stalled Replication Forks at Common Fragile Sites during Mitosis. Molecular Cell. 66 (5), pp. 658-671. doi:10.1016/j.molcel.2017.05.006

A neutralizing antibody to the a chain of abrin inhibits abrin toxicity both in vitro and in vivo
Surendranath, K. and Karande A.A. 2008. A neutralizing antibody to the a chain of abrin inhibits abrin toxicity both in vitro and in vivo. Clinical and Vaccine Immunology. 15 (5), pp. 737-743. doi:10.1128/CVI.00254-07

Production of paclitaxel by Fusarium solani isolated from Taxus celebica
Chakravarthi, B.V., Das, P., Surendranath, K., Karande, A.A. and Jayabaskaran, C. 2008. Production of paclitaxel by Fusarium solani isolated from Taxus celebica. Journal of Biosciences. 33 (2), pp. 259-267. doi:10.1007/s12038-008-0043-6

Structure-function analysis and insights into the reduced toxicity of Abrus precatorius agglutinin I in relation to abrin
Bagaria, A., Surendranath, K., Ramagopal, U.A., Ramakumar, S. and Karande, A.A. 2006. Structure-function analysis and insights into the reduced toxicity of Abrus precatorius agglutinin I in relation to abrin. Journal of Biological Chemistry . 281, pp. 34465-34474. doi:10.1074/jbc.M601777200

Permalink - https://westminsterresearch.westminster.ac.uk/item/q32y3/-abrus-toxins-study-on-a-dangerous-lectin-duo-present-in-the-seeds-of-indian-licorice


Share this
Tweet
Email