Title | Post-exercise cardiac troponin release is related to exercise traning history |
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Type | Journal article |
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Authors | Mehta, R., Gaze, D.C., Mohan, S., Williams, K.L., Sprung, V., George, K., Jeffries, R., Hudson, Z., Perry, M. and Shave, R. |
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Abstract | Marathon running can increase circulating cardiac troponin above the diagnostic criteria for myocardial infarction. We determined whether prior-exercise experience (training history) might be related to the magnitude of immediate post-race troponin release following completion of the London Marathon in a group of non-elite runners. Using a prospective study design, 52 runners were recruited into either HIGH T-E (trained-experience) (n=27) or LOW T-E (n=25) groups. Cardiac troponin I (cTnI) release following race completion was compared between these 2 groups. To examine relationships between cTnI release and participant demographic and indices of prior training experience an additional 52 runners who did not meet the criteria for either the HIGH T-E or LOW T-E groups were also recruited. The combined data from all 104 runners was analysed using multivariate linear regression analysis. The results revealed a significant difference in post marathon circulating cTnI between LOW T-E runners (median: 0.11 µg/L; interquartile range [IQR]: 0.03–0.18 µg/L) and HIGH T-E runners (median: 0.03 µg/L; IQR 0.02–0.057 µg/L) (p<0.05). Average miles run per week in the last 3 years, a marker of total training experience, encompassing training volume and duration, was negatively associated with post-marathon cTnI release (p<0.001). In conclusion, exercise-induced cTnI release is strongly related to previous training experience. |
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Keywords | marathon - training - cardiac damage |
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Journal | International Journal of Sports Medicine |
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Journal citation | 33 (5), pp. 333-337 |
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ISSN | 0172-4622 |
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Year | 2012 |
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Publisher | Georg Thieme Verlag |
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Digital Object Identifier (DOI) | https://doi.org/10.1055/s-0031-1301322 |
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Publication dates |
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Published | May 2012 |
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