Special Topic: "Animal Models of Human Disease"
Lange, S. and Inal, J.M. 2022. Special Topic: "Animal Models of Human Disease". MDPI.
Lange, S. and Inal, J.M. 2022. Special Topic: "Animal Models of Human Disease". MDPI.
Title | Special Topic: "Animal Models of Human Disease" |
---|---|
Authors | Lange, S. and Inal, J.M. |
Description | The use of animal models of human disease is critical for furthering our understanding of disease mechanisms, for the discovery of novel targets for treatment, and for translational research. This Special Topic aims to collect state-of-the-art primary research studies and review articles from international experts and leading groups using animal models to study human diseases. Submissions are welcome on a wide range of animal models and pathologies, including infectious disease, acute injury, regeneration, cancer, autoimmunity, and degenerative and chronic disease. Topic Editors: Participating journals: Biomedicines, Cells, Current Issues in Molecular Biology, Diagnostics, Genes, International Journal of Molecular Sciences, International Journal of Translational Medicine Abstract submission deadline |
Year | 2022 |
Output media | MDPI |
Keywords | animal models; human disease; pathology; pathobiology; chronic disease; acute injury; regeneration; infectious disease; cancer; autoimmunity; neurodegenerative disease; comparative animal models; extracellular vesicles; liquid biopsy; biomarkers |
Publisher | MDPI |
Publication dates | |
Published | 01 Sep 2022 |
File | File Access Level Open (open metadata and files) |
Web address (URL) | https://www.mdpi.com/topics/Model_Animals#information |
Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches
Joshua A. Welsh, Deborah Goberdhan, Lorraine O'Driscoll, Edit Buzás, Cherie Blenkiron, Bussolati B, Joseph Whitley, Dolores Di Vizio, Tom A. P. Driedonks, Uta Erdbrügger, Juan M Falcon-Perez, Qing‐Ling Fu, Andrew Hill, Metka Lenassi, Sai Kiang Lim, Mỹ G. Mahoney, Sujata Mohanty, Andreas Möller, Rienk Nieuwland, Takahiro Ochiya, Susmita Sahoo, Ana Claudia Torrecilhas, Lei Zheng, Andries Zijlstra, Sarah Abuelreich, Reem Bagabas, Paolo Bergese, Esther M. Bridges, Marco Brucale, Dylan Burger, Randy Carney, Emanuele Cocucci, Rossella Crescitelli, Edveena Hanser, Adrian L. Harris, Norman Haughey, An Hendrix, Alexander R. Ivanov, Tijana Jovanovic‐Talisman, Nicole A. Kruh‐Garcia, Vroniqa Ku'ulei‐Lyn Faustino, Diego Kyburz, Cecilia Lässer, Kathleen M. Lennon, Jan Lötvall, Adam L. Maddox, Elena Martens-Uzunova, Rachel R. Mizenko, Lauren Newman, Andrea Ridolfi, Eva Rohde, Lange, S. and Dina Ahmed 2024. Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches. Journal of Extracellular Vesicles. 13 (2) e12404. https://doi.org/10.1002/jev2.12404
Immunopathology of Hematodinium sp. infection of decapod crustaceans
Coates, C., Rowley, A. and Lange, S. 2023. Immunopathology of Hematodinium sp. infection of decapod crustaceans. Developmental and Comparative Immunology. 148 104936. https://doi.org/10.1016/j.dci.2023.104936
A Coxsackievirus B1-mediated nonlytic Extracellular Vesicle-to-cell mechanism of virus transmission and its possible control through modulation of EV release
Jorfi, S., Ansa-Addo, E.A., Mariniello, K., Warde, P., Bin Senian, A.A., Stratton, D., Bax, B.E., Levene, M., Lange, S. and Inal, J.M. 2023. A Coxsackievirus B1-mediated nonlytic Extracellular Vesicle-to-cell mechanism of virus transmission and its possible control through modulation of EV release. Journal of General Virology. 104 (9) 001884. https://doi.org/10.1099/jgv.0.001884
The Extracellular Vesicle Citrullinome and Signature in a Piglet Model of Neonatal Seizures
Mitra, S., Harvey-Jones, K., Kraev, I., Verma, V., Meehan, C., Mintoft, A., Norris, G., Campbell, E., Tucker, K., Robertson, N.J., Hristova, M. and Lange, S. 2023. The Extracellular Vesicle Citrullinome and Signature in a Piglet Model of Neonatal Seizures. International Journal of Molecular Sciences. 24 (14) 11529. https://doi.org/10.3390/ijms241411529
Extracellular Vesicles in Phylogeny
Lange, S. 2023. Extracellular Vesicles in Phylogeny. International Journal of Molecular Sciences. 24 (13) 10466. https://doi.org/10.3390/ijms241310466
Extracellular vesicle signatures and protein citrullination are modified in shore crabs (Carcinus maenas) infected with Hematodinium sp
Coates, C., Kraev, I., Rowley, A. and Lange, S. 2023. Extracellular vesicle signatures and protein citrullination are modified in shore crabs (Carcinus maenas) infected with Hematodinium sp. Virulence. 14 (1) 2180932. https://doi.org/10.1080/21505594.2023.2180932
Special Issue "The Exposome in Immune Evolution, Health and Disease"
Lange, S. 2023. Special Issue "The Exposome in Immune Evolution, Health and Disease". Biology.
Differential, Stage Dependent Detection of Peptidylarginine Deiminases and Protein Deimination in Lewy Body Diseases-Findings from a Pilot Study
Mercer, A., Jaunmuktane, Z., Hristova, M. and Lange, S. 2022. Differential, Stage Dependent Detection of Peptidylarginine Deiminases and Protein Deimination in Lewy Body Diseases-Findings from a Pilot Study. International Journal of Molecular Sciences. 23 (21) 13117. https://doi.org/10.3390/ijms232113117
microRNA 1307 Is a Potential Target for SARS-CoV-2 Infection: An <i>in Vitro</i> Model
Arisan, Elif Damla, Dart, D. Alwyn, Grant, Guy H., Dalby, A.R., Kancagi, Derya Dilek, Turan, Raife Dilek, Yurtsever, Bulut, Karakus, Gozde Sir, Ovali, Ercument, Lange, Sigrun and Uysal-Onganer, P. 2022. microRNA 1307 Is a Potential Target for SARS-CoV-2 Infection: An <i>in Vitro</i> Model. ACS Omega. 7 (42), pp. 38003-38014. https://doi.org/10.1021/acsomega.2c05245
Special Issue: “State-of-the-Art Neurobiology in the U.K."
Lange, S. 2022. Special Issue: “State-of-the-Art Neurobiology in the U.K.". MDPI.
A Pilot Study on Peptidylarginine Deiminases and Protein Deimination in Animal Cancers across Vertebrate Species
Inal, J.M., Hristova, M. and Lange, S. 2022. A Pilot Study on Peptidylarginine Deiminases and Protein Deimination in Animal Cancers across Vertebrate Species. International Journal of Molecular Sciences. 23 (15) e8697. https://doi.org/10.3390/ijms23158697
Acute Hypoxia Alters Extracellular Vesicle Signatures and the Brain Citrullinome of Naked Mole-Rats (Heterocephalus glaber)
D'alessio, S., Cheng, H., Eaton, L., Kraev, I., Pamenter, M.E. and Lange, S. 2022. Acute Hypoxia Alters Extracellular Vesicle Signatures and the Brain Citrullinome of Naked Mole-Rats (Heterocephalus glaber). International Journal of Molecular Sciences. 23 (9) 4683. https://doi.org/10.3390/ijms23094683
microRNA-21 Regulates Stemness in Pancreatic Ductal Adenocarcinoma Cells
Mortoglou, M., Miralles, F., Arisan, E.D., Dart, A., Jurcevic, S., Lange, S. and Uysal Onganer, P. 2022. microRNA-21 Regulates Stemness in Pancreatic Ductal Adenocarcinoma Cells. International Journal of Molecular Sciences. 23 (3) 1275. https://doi.org/10.3390/ijms23031275
Special Issue: “Extracellular Vesicles in Phylogeny”
Lange, S. 2021. Special Issue: “Extracellular Vesicles in Phylogeny”. MDPI.
Special Issue: “Cancers across Phylogeny and Cancer Evolution”
Lange, S. 2021. Special Issue: “Cancers across Phylogeny and Cancer Evolution” . MDPI.
Controlled Delivery of Pan-PAD-Inhibitor Cl-Amidine Using Poly(3-Hydroxybutyrate) Microspheres.
Ahmed, D., Puthussery, Hima, Basnett, Pooja, Knowles, J., Lange, S. and Roy, I. 2021. Controlled Delivery of Pan-PAD-Inhibitor Cl-Amidine Using Poly(3-Hydroxybutyrate) Microspheres. International Journal of Molecular Sciences. 22 (23) 12852. https://doi.org/10.3390/ijms222312852
Controlled Delivery of Pan-PAD-Inhibitor Cl-Amidine Using Poly(3-Hydroxybutyrate) Microspheres
Ahmed, D., Puthussery, H., Basnett, P., Knowles, J., Lange, S. and Roy, I. 2021. Controlled Delivery of Pan-PAD-Inhibitor Cl-Amidine Using Poly(3-Hydroxybutyrate) Microspheres. International Journal of Molecular Sciences. 22 (23) e12852. https://doi.org/10.3390/ijms222312852
Preliminary Investigations Into the Effect of Exercise-Induced Muscle Damage on Systemic Extracellular Vesicle Release in Trained Younger and Older Men
Kyriakidou, Y., Cooper, I., Kraev, I., Lange, S. and Elliott, B. 2021. Preliminary Investigations Into the Effect of Exercise-Induced Muscle Damage on Systemic Extracellular Vesicle Release in Trained Younger and Older Men. Frontiers in Physiology. 12 723931. https://doi.org/10.3389/fphys.2021.723931
Extracellular Vesicle Signatures and Post-Translational Protein Deimination in Purple Sea Urchin ( Strongylocentrotus purpuratus ) Coelomic Fluid—Novel Insights into Echinodermata Biology
D'alessio, S., Buckley, K., Kraev, Igor, Hayes, P.M. and Lange, S. 2021. Extracellular Vesicle Signatures and Post-Translational Protein Deimination in Purple Sea Urchin ( Strongylocentrotus purpuratus ) Coelomic Fluid—Novel Insights into Echinodermata Biology. Biology. 10 (9) 866. https://doi.org/10.3390/biology10090866
Post-translational protein deimination signatures in sea lamprey (Petromyzon marinus) plasma and plasma-extracellular vesicles
Rast, J.P., D'alessio, S., Kraev, I. and Lange, S. 2021. Post-translational protein deimination signatures in sea lamprey (Petromyzon marinus) plasma and plasma-extracellular vesicles. Developmental & Comparative Immunology. 125 (2021) 104225. https://doi.org/10.1016/j.dci.2021.104225
Post-Translational Protein Deimination Signatures in Plasma and Plasma EVs of Reindeer ( Rangifer tarandus )
D'alessio, S., Thorgeirsdóttir, Stefanía, Kraev, Igor, Skírnisson, Karl and Lange, S. 2021. Post-Translational Protein Deimination Signatures in Plasma and Plasma EVs of Reindeer ( Rangifer tarandus ). Biology. 10 (3) e222. https://doi.org/10.3390/biology10030222
Peptidylarginine Deiminase (PAD) and Post-Translational Protein Deimination—Novel Insights into Alveolata Metabolism, Epigenetic Regulation and Host–Pathogen Interactions
Kristmundsson, Árni, Erlingsdóttir, Ásthildur and Lange, S. 2021. Peptidylarginine Deiminase (PAD) and Post-Translational Protein Deimination—Novel Insights into Alveolata Metabolism, Epigenetic Regulation and Host–Pathogen Interactions. Biology. 10 (3) e177. https://doi.org/10.3390/biology10030177
Editorial: Tissue Remodeling in Health and Disease Caused by Bacteria, Parasites, Fungi, and Viruses
Lange, S. and Ramirez, M.I. 2021. Editorial: Tissue Remodeling in Health and Disease Caused by Bacteria, Parasites, Fungi, and Viruses. Frontiers in Cellular and Infection Microbiology. 11 642311. https://doi.org/10.3389/fcimb.2021.642311
Peptidylarginine Deiminase Inhibitor Application, Using Cl-Amidine, PAD2, PAD3 and PAD4 Isozyme-Specific Inhibitors in Pancreatic Cancer Cells, Reveals Roles for PAD2 and PAD3 in Cancer Invasion and Modulation of Extracellular Vesicle Signatures
Uysal Onganer, P., D'alessio, S., Mortoglou, M., Kraev, I. and Lange, S. 2021. Peptidylarginine Deiminase Inhibitor Application, Using Cl-Amidine, PAD2, PAD3 and PAD4 Isozyme-Specific Inhibitors in Pancreatic Cancer Cells, Reveals Roles for PAD2 and PAD3 in Cancer Invasion and Modulation of Extracellular Vesicle Signatures. International Journal of Molecular Sciences. 22 (3) 1396. https://doi.org/10.3390/ijms22031396
MicroRNAs for Virus Pathogenicity and Host Responses, Identified in SARS-CoV-2 Genomes, May Play Roles in Viral-Host Co-Evolution in Putative Zoonotic Host Species
Lange, S., Arisan, E.D., Grant, G.H. and Uysal Onganer, P. 2021. MicroRNAs for Virus Pathogenicity and Host Responses, Identified in SARS-CoV-2 Genomes, May Play Roles in Viral-Host Co-Evolution in Putative Zoonotic Host Species. MDPI Viruses. 13 (1), p. 117 10.3390/v13010117 . https://doi.org/10.3390/v13010117
The Proteome and Citrullinome of Hippoglossus hippoglossus Extracellular Vesicles—Novel Insights into Roles of the Serum Secretome in Immune, Gene Regulatory and Metabolic Pathways
Magnadóttir, B., Kraev, I., Dodds, A.W. and Lange, S. 2021. The Proteome and Citrullinome of Hippoglossus hippoglossus Extracellular Vesicles—Novel Insights into Roles of the Serum Secretome in Immune, Gene Regulatory and Metabolic Pathways. International Journal of Molecular Sciences. 22 (2) 875. https://doi.org/10.3390/ijms22020875
Peptidylarginine deiminases and extracellular vesicles: prospective drug targets and biomarkers in central nervous system diseases and repair.
Lange, Sigrun 2021. Peptidylarginine deiminases and extracellular vesicles: prospective drug targets and biomarkers in central nervous system diseases and repair. Neural Regeneration Research. 16 (5), pp. 934-938. https://doi.org/NeuralRegenRes_2021_16_5_934_297058
Patterns in nature - the true art of microscopy
Lange, S. 2020. Patterns in nature - the true art of microscopy. University of Westminster
Extracellular Vesicles and Post-Translational Protein Deimination Signatures in Mollusca—The Blue Mussel ( Mytilus edulis ), Soft Shell Clam ( Mya arenaria ), Eastern Oyster ( Crassostrea virginica ) and Atlantic Jacknife Clam ( Ensis leei )
Bowden, Timothy J., Kraev, Igor and Lange, S. 2020. Extracellular Vesicles and Post-Translational Protein Deimination Signatures in Mollusca—The Blue Mussel ( Mytilus edulis ), Soft Shell Clam ( Mya arenaria ), Eastern Oyster ( Crassostrea virginica ) and Atlantic Jacknife Clam ( Ensis leei ). Biology. 9 (12) e416. https://doi.org/10.3390/biology9120416
Peptidylarginine Deiminase inhibition abolishes the production of large extracellular vesicles from Giardia intestinalis, affecting host-pathogen interactions by hindering adhesion to host cells
Gavinho, B., Sabatke, B., Rossi, I., Feijoli, V., Macedo, J., Evans-Osses, I., Palmisano, G., Lange, S. and Ramirez, M.I. 2020. Peptidylarginine Deiminase inhibition abolishes the production of large extracellular vesicles from Giardia intestinalis, affecting host-pathogen interactions by hindering adhesion to host cells. Frontiers in Cellular and Infection Microbiology. 10 417. https://doi.org/10.1101/586438
Extracellular Vesicles and Post-translational Protein Deimination Signatures in Haemolymph of the American Lobster (Homarus americanus)
Bowden, T.J., Kraev, I. and Lange, S. 2020. Extracellular Vesicles and Post-translational Protein Deimination Signatures in Haemolymph of the American Lobster (Homarus americanus) . Fish and Shellfish Immunology. 106, pp. 79-102 FSIM-D-20-00642. https://doi.org/10.1016/j.fsi.2020.06.053
Data‐driven integration of hippocampal CA1 synaptic physiology in silico
Ecker, A., Romani, A., Sáray, S., Káli,S., Migliore, M., Falck, J., Lange, S., Mercer, A., Thomson, A.M., Muller, M., Reimann, M.W. and Ramaswamy, S. 2020. Data‐driven integration of hippocampal CA1 synaptic physiology in silico. Hippocampus. 30 (11), pp. 1129-1145. https://doi.org/10.1002/hipo.23220
The Prediction of miRNAs in SARS-CoV-2 Genomes: hsa-miR Databases Identify 7 Key miRs Linked to Host Responses and Virus Pathogenicity-Related KEGG Pathways Significant for Comorbidities
Arisan, E.D., Dart, A., Grant, G.H., Arisan, S., Cuhadaroglu, S., Lange, S. and Uysal Onganer, P. 2020. The Prediction of miRNAs in SARS-CoV-2 Genomes: hsa-miR Databases Identify 7 Key miRs Linked to Host Responses and Virus Pathogenicity-Related KEGG Pathways Significant for Comorbidities. MDPI Viruses. 12 (6) 614. https://doi.org/10.3390/v12060614
Post-Translational Protein Deimination Signatures in Serum and Serum-Extracellular Vesicles of Bos taurus Reveal Immune, Anti-Pathogenic, Anti-Viral, Metabolic and Cancer-Related Pathways for Deimination
Criscitiello, M.F., Kraev, I. and Lange, S. 2020. Post-Translational Protein Deimination Signatures in Serum and Serum-Extracellular Vesicles of Bos taurus Reveal Immune, Anti-Pathogenic, Anti-Viral, Metabolic and Cancer-Related Pathways for Deimination. International Journal of Molecular Sciences. 21 (8) 2861. https://doi.org/10.3390/ijms21082861
Post-translational Protein Deimination Signatures and Extracellular Vesicles (EVs) in the Atlantic Horseshoe Crab (Limulus polyphemus)
Bowden, T.J., Kraev, I. and Lange, S. 2020. Post-translational Protein Deimination Signatures and Extracellular Vesicles (EVs) in the Atlantic Horseshoe Crab (Limulus polyphemus) . Developmental and Comparative Immunology. 110 103714. https://doi.org/10.1016/j.dci.2020.103714
Deimination Protein Profiles in Alligator mississippiensis Reveal Plasma and Extracellular Vesicle- specific Signatures Relating to Immunity, Metabolic Function and Gene Regulation
Criscitiello, M.F., Kraev, I., Petersen, L.H. and Lange, S. 2020. Deimination Protein Profiles in Alligator mississippiensis Reveal Plasma and Extracellular Vesicle- specific Signatures Relating to Immunity, Metabolic Function and Gene Regulation. Frontiers in Immunology. 11 651. https://doi.org/10.3389/fimmu.2020.00651
Deiminated Proteins and Extracellular Vesicles as Novel Biomarkers in Pinnipeds: Grey seal (Halichoerus gryptus) and Harbour seal (Phoca vitulina)
Magnadóttir, B., Uysal Onganer, P., Kraev, I., Svansson, V., Skírnisson, K. and Lange, S. 2020. Deiminated Proteins and Extracellular Vesicles as Novel Biomarkers in Pinnipeds: Grey seal (Halichoerus gryptus) and Harbour seal (Phoca vitulina). Biochimie . 171-172, pp. 79-90. https://doi.org/10.1016/j.biochi.2020.02.017
Deiminated proteins and extracellular vesicles - Novel serum biomarkers in whales and orca
Magnadóttir, B., Uysal-Onganer, P., Kraev, I., Svansson, V., Hayes, P.M. and Lange, S. 2020. Deiminated proteins and extracellular vesicles - Novel serum biomarkers in whales and orca. Comparative Biochemistry and Physiology - Part D: Genomics and Proteomics. 34, p. 100676 100676. https://doi.org/10.1016/j.cbd.2020.100676
Protein Deimination and Extracellular Vesicle Profiles in Antarctic Seabirds
Phillips, R.A., Kraev, I. and Lange, S. 2020. Protein Deimination and Extracellular Vesicle Profiles in Antarctic Seabirds. MDPI Biology. 9 (1) 15. https://doi.org/10.3390/biology9010015
Plasma mEV levels in Ghanain malaria patients with low parasitaemia are higher than those of healthy controls, raising the potential for parasite markers in mEVs as diagnostic targets
Antwi-Baffour, S., Malibha-Pinchbeck, M., Stratton, D., Jorfi, S., Lange, S. and Inal, J.M. 2020. Plasma mEV levels in Ghanain malaria patients with low parasitaemia are higher than those of healthy controls, raising the potential for parasite markers in mEVs as diagnostic targets. Journal of Extracellular Vesicles. 9, 2020 (issue 1) 1697124 . https://doi.org/10.1080/20013078.2019.1697124
Extracellular Vesicles, Deiminated Protein Cargo and microRNAs are Novel Serum Biomarkers for Environmental Rearing Temperature in Atlantic Cod (Gadus morhua L.)
Magnadóttir, B., Uysal Onganer, P., Kraev, I., Dodds, A.W., Gudmundsdottir, S. and Lange, S. 2020. Extracellular Vesicles, Deiminated Protein Cargo and microRNAs are Novel Serum Biomarkers for Environmental Rearing Temperature in Atlantic Cod (Gadus morhua L.) . Aquaculture Reports. 16 100245. https://doi.org/10.1016/j.aqrep.2019.100245
Deiminated Proteins in Extracellular Vesicles and Serum of Llama (Lama glama) - Novel Insights into Camelid Immunity
Criscitiello, M.F., Kraev, I. and Lange, S. 2020. Deiminated Proteins in Extracellular Vesicles and Serum of Llama (Lama glama) - Novel Insights into Camelid Immunity. Molecular Immunology. 117, pp. 37-53 MIMM_5890. https://doi.org/10.1016/j.molimm.2019.10.017
Peptidylarginine Deiminase Inhibition Abolishes the Production of Large Extracellular Vesicles From Giardia intestinalis, Affecting Host-Pathogen Interactions by Hindering Adhesion to Host Cells
Gavinho, B., Sabatke, B., Feijoli, V., Rossi, I., da Silva, J. M., Evans-Osses, I., Palmisano. G., Lange, S. and Ramirez, M.I. 2020. Peptidylarginine Deiminase Inhibition Abolishes the Production of Large Extracellular Vesicles From Giardia intestinalis, Affecting Host-Pathogen Interactions by Hindering Adhesion to Host Cells. Frontiers in Cellular and Infection Microbiology. 10 417. https://doi.org/10.3389/fcimb.2020.00417
Special Issue: Peptidylarginine Deiminases and Protein Deimination in Health and Disease
Lange, S. and Nicholas, A.P. 2019. Special Issue: Peptidylarginine Deiminases and Protein Deimination in Health and Disease. MDPI.
Curcumin: novel treatment in neonatal hypoxic-ischaemic brain injury
Rocha-Ferreira, E., Sisa, C., Bright, S., Fautz, T., Harris, M., Contreras Riquelme, I., Agwu, C., Kurulday, T., Mistry, B., Hill, D., Lange, S. and Hristova, M. 2019. Curcumin: novel treatment in neonatal hypoxic-ischaemic brain injury. Frontiers in Physiology. 10 1351. https://doi.org/10.3389/fphys.2019.01351
Cannabidiol is a Novel Modulator of Bacterial Membrane Vesicles
Kosgodage, U., Matewele, P., Awamaria, B., Kraev, I., Warde, P., Mastroianni, G., Nunn, A., Guy, G.W., Bell, J.D., Inal, J.M. and Lange, S. 2019. Cannabidiol is a Novel Modulator of Bacterial Membrane Vesicles. Frontiers in Cellular and Infection Microbiology. 9 324. https://doi.org/10.3389/fcimb.2019.00324
Complement component C4-like protein in Atlantic cod (Gadus morhua L.) - Detection in ontogeny and identification of post-translational deimination in serum and extracellular vesicles
Lange, S., Kraev, I., Magnadottir, B. and Dodds, A.W. 2019. Complement component C4-like protein in Atlantic cod (Gadus morhua L.) - Detection in ontogeny and identification of post-translational deimination in serum and extracellular vesicles. Developmental and Comparative Immunology. 101 103437. https://doi.org/10.1016/j.dci.2019.103437
Deiminated Proteins in Extracellular Vesicles and Plasma of Nurse Shark (Ginglymostoma cirratum) - Novel Insights into Shark Immunity
Criscitiello, M.F., Kraev, I. and Lange, S. 2019. Deiminated Proteins in Extracellular Vesicles and Plasma of Nurse Shark (Ginglymostoma cirratum) - Novel Insights into Shark Immunity. Fish and Shellfish Immunology. 92, pp. 249-255 YFSIM_6208. https://doi.org/10.1016/j.fsi.2019.06.012
Peptidylarginine Deiminase Inhibitors Reduce Bacterial Membrane Vesicle Release and Sensitise Bacteria to Antibiotic Treatment
Kosgodage, U., Matewele, P., Mastroianni, G., Kraev, I., Brotherton, D., Awamaria, B., Nicholas, A.P., Lange, S. and Inal, J.M. 2019. Peptidylarginine Deiminase Inhibitors Reduce Bacterial Membrane Vesicle Release and Sensitise Bacteria to Antibiotic Treatment. Frontiers in Cellular and Infection Microbiology. 9 227. https://doi.org/10.3389/fcimb.2019.00227
Extracellular Vesicles from Cod (Gadus morhua L.) Mucus contain Innate Immune Factors and Deiminated Protein Cargo
Magnadóttir, B., Kraev, I., Gudmundsdottir, S., Dodds, A.W. and Lange, S. 2019. Extracellular Vesicles from Cod (Gadus morhua L.) Mucus contain Innate Immune Factors and Deiminated Protein Cargo. Developmental and Comparative Immunology. p. 103397 103397. https://doi.org/10.1016/j.dci.2019.103397
Mesenchymal Stromal Cell derived Extracellular Vesicles reduce Hypoxia-Ischaemia Induced Perinatal Brain Injury
Sisa, C., Kholia, S., Naylor, J., Herrera Sanchez, M.B., Bruno, S., Deregibus, M.C., Camussi, G., Inal, J.M., Lange, S. and Hristova, M. 2019. Mesenchymal Stromal Cell derived Extracellular Vesicles reduce Hypoxia-Ischaemia Induced Perinatal Brain Injury. Frontiers in Physiology. 10 282. https://doi.org/10.3389/fphys.2019.00282
Peptidylarginine Deiminases Post-translationally deiminate Prohibitin and modulate Extracellular Vesicle Release and microRNAs in Glioblastoma Multiforme
Kosgodage, U., Uysal Onganer, P., Maclatchy, A., Kraev, I., Chatterton, N.P., Nicholas, A.P., Inal, J.M. and Lange, S. 2019. Peptidylarginine Deiminases Post-translationally deiminate Prohibitin and modulate Extracellular Vesicle Release and microRNAs in Glioblastoma Multiforme . International Journal of Molecular Sciences. 20 (1) 103. https://doi.org/10.3390/ijms20010103
A novel ladder-like lectin relates to sites of mucosal immunity in Atlantic Halibut (Hippoglossus hippoglossus L.)
Magnadóttir, B., Gudmundsdottir, S. and Lange, S. 2019. A novel ladder-like lectin relates to sites of mucosal immunity in Atlantic Halibut (Hippoglossus hippoglossus L.) . Fish & Shellfish Immunology. 87, pp. 9-12. https://doi.org/10.1016/j.fsi.2018.12.034
Cannabidiol Affects Extracellular Vesicle Release, miR21 and miR126, and Reduces Prohibitin Protein in Glioblastoma Multiforme Cells
Kosgodage, U., Uysal Onganer, P., Maclatchy, A., Mould, R., Nunn, A.V.W., Guy, G.W., Kraev, I., Chatterton, N.P., Thomas, E.L., Inal, J.M., Bell, J.D. and Lange, S. 2019. Cannabidiol Affects Extracellular Vesicle Release, miR21 and miR126, and Reduces Prohibitin Protein in Glioblastoma Multiforme Cells. Translational Oncology. 12 (3), pp. 513-522. https://doi.org/10.1016/j.tranon.2018.12.004
Peptidylarginine deiminase and deiminated proteins are detected throughout early halibut ontogeny - Complement components C3 and C4 are post-translationally deiminated in halibut (Hippoglossus hippoglossus L.)
Magnadóttir, B., Bragason, B.T., Bricknell, I.R., Bowden, T., Nicholas, A.P., Hristova, M., Gudmundsdottir, S., Dodds, A.W. and Lange, S. 2019. Peptidylarginine deiminase and deiminated proteins are detected throughout early halibut ontogeny - Complement components C3 and C4 are post-translationally deiminated in halibut (Hippoglossus hippoglossus L.). Developmental and Comparative Immunology. 92, pp. 1-19. https://doi.org/10.1016/j.dci.2018.10.016
The physiological variability of channel density in hippocampal CA1 pyramidal cells and interneurons explored using a unified data-driven modeling workflow
Migliore, R., Lupascu, C.A., Bologna, L.L., Romani, R., Courcol, J-D., Antonel, S., Van Geit, W.A.H., Thompson, A.M., Mercer, A., Lange, S., Falck, J., Rossert, C.A., Shi, Y., Hagens, O., Pezzoli, M., Freund, T.F., Muller, E.B., Kali, S., Schurmann, F., Markram, H. and Migliore, M. 2018. The physiological variability of channel density in hippocampal CA1 pyramidal cells and interneurons explored using a unified data-driven modeling workflow. PLOS Computational Biology. 14 (9) e1006423. https://doi.org/10.1371/journal.pcbi.1006423
Cannabidiol (CBD) is a Novel Inhibitor for Exosome and Microvesicle (EMV) Release in Cancer
Kosgodage, U., Mould, R., Henley, A., Nunn, A.V.W., Guy, G.W., Thomas, E.L., Inal, J.M., Bell, J.D. and Lange, S. 2018. Cannabidiol (CBD) is a Novel Inhibitor for Exosome and Microvesicle (EMV) Release in Cancer. Frontiers in Pharmacology. 9 889. https://doi.org/10.3389/fphar.2018.00889
Post-translational Protein Deimination in Cod (Gadus morhua L.) Ontogeny: Novel Roles in Tissue Remodelling and Mucosal Immune Defences?
Magnadóttir, B., Hayes, P.M., Hristova, M., Bragason, B., Nicholas, A.P., Dodds, A.W., Gudmundsdottir, S. and Lange, S. 2018. Post-translational Protein Deimination in Cod (Gadus morhua L.) Ontogeny: Novel Roles in Tissue Remodelling and Mucosal Immune Defences? Developmental and Comparative Immunology. 87, pp. 157-170. https://doi.org/10.1016/j.dci.2018.06.006
Pentraxins CRP-I and CRP-II are post-translationally deiminated and differ in tissue specificity in cod (Gadus morhua L.) ontogeny
Magnadóttir, B., Hayes, P.M., Gisladottir, B., Bragason, B., Hristova, M., Nicholas, A.P., Gudmundsdottir, S. and Lange, S. 2018. Pentraxins CRP-I and CRP-II are post-translationally deiminated and differ in tissue specificity in cod (Gadus morhua L.) ontogeny. Developmental and Comparative Immunology. 87, pp. 1-11. https://doi.org/10.1016/j.dci.2018.05.014
Data-driven computational modeling of CA1 hippocampal principal cells and interneurons
Lange, S., migliore, S. and Lupascu, A.C. 2017. Data-driven computational modeling of CA1 hippocampal principal cells and interneurons. 26th Annual Computational Neuroscience Meeting (CNS*2017). Antwerp, Belgium 15 - 20 Jul 2017 BioMed Central. https://doi.org/10.1186/s12868-017-0372-1
Treatment of Prostate Cancer Using Deimination Antagonists and Microvesicle Technology
Lange, S., Kholia, S., Kosgodage, U. and Inal, J.M. 2017. Treatment of Prostate Cancer Using Deimination Antagonists and Microvesicle Technology. in: Nicholas, A.P., Bhattacharya, S. and Thompson, P.R. (ed.) Protein Deimination in Human Health and Disease Cham, Switzerland Springer. pp. 413-425
Protein Deimination in Protein Misfolding Disorders - Modelled in Human induced Pluripotent Stem Cells (iPSCs)
Lange, S., Wray, S., Devine, M., Matarin, M. and Hardy, J. 2017. Protein Deimination in Protein Misfolding Disorders - Modelled in Human induced Pluripotent Stem Cells (iPSCs). in: Nicholas, A.P., Battacharya, S.K. and Thompson, P.R. (ed.) Protein Deimination in Human Health and Disease Cham, Switzerland Springer. pp. 227-239
Peptidylarginine Deiminases-Roles in Cancer and Neurodegeneration and Possible Avenues for Therapeutic Intervention via Modulation of Exosome and Microvesicle (EMV) Release?
Lange, S., Gallagher, M, Kholia, S., Kosgodage, U., Hristova, M., Hardy, J. and Inal, J.M. 2017. Peptidylarginine Deiminases-Roles in Cancer and Neurodegeneration and Possible Avenues for Therapeutic Intervention via Modulation of Exosome and Microvesicle (EMV) Release? International Journal of Molecular Sciences. 18 (6) 1196. https://doi.org/10.3390/ijms18061196
Chloramidine/Bisindolylmaleimide-I-Mediated Inhibition of Exosome and Microvesicle Release and Enhanced Efficacy of Cancer Chemotherapy
Kosgodage, U., Trindade R.P., Thompson, P.R., Inal, J.M. and Lange, S. 2017. Chloramidine/Bisindolylmaleimide-I-Mediated Inhibition of Exosome and Microvesicle Release and Enhanced Efficacy of Cancer Chemotherapy. International Journal of Molecular Sciences. 18 (5) 1007. https://doi.org/10.3390/ijms18051007
The emerging role of exosome and microvesicle- (EMV-) based cancer therapeutics and immunotherapy
Moore, C., Kosgodage, U., Lange, S. and Inal, J.M. 2017. The emerging role of exosome and microvesicle- (EMV-) based cancer therapeutics and immunotherapy. International Journal of Cancer. 141 (3), pp. 428-436. https://doi.org/10.1002/ijc.30672
Data-driven model of the hippocampus using the HBP Brain Simulation Platform
Romani, A., Antille, N., Atenekeng, G., Courcol, J.D., Devresse, A., Dynes, J.A., Gevaert, M., Gonzalo, J.K., Gulyas, A., Kali, S., Kanari, L., Lange, S., Mercer, A., Migliore, M., Muller, E.B., Palacios, J.P., Ramaswamy, S., Reimann, M., Riquelme, R.L., Rössert, C.A., Ying, S., Shillcock, J., Telefont, M., Van Geit, W.A.H., Vanherpe, L., Markram, H. and Thomson, A. 2016. Data-driven model of the hippocampus using the HBP Brain Simulation Platform. 10th FENS Forum of Neuroscience. Copenhagen, Denmark 02 - 06 Jul 2016
PF7.09 Non-phagocytic epithelial cells take up microvesicles by micropinocytosis
Lange, S., Kosgodage, U. and Inal, J.M. 2016. PF7.09 Non-phagocytic epithelial cells take up microvesicles by micropinocytosis. The Fifth International Meeting of ISEV, ISEV 2016. Rotterdam, Netherlands 04 - 07 May 2016 Co-Action Publishing.
PW1.04. Inhibitors of microvesicle release with the potential to enhance effectivity of cancer chemotherapy
Lange, S., Kosgodage, U. and Inal, J.M. 2016. PW1.04. Inhibitors of microvesicle release with the potential to enhance effectivity of cancer chemotherapy. The Fifth International Meeting of ISEV, ISEV 2016. Rotterdam, Netherlands 04 - 07 May 2016 Co-Action Publishing. https://doi.org/10.3402/jev.v5.31552
Peptidylarginine deiminases as drug targets in neonatal hypoxic-ischemic encephalopathy
Lange, S. 2016. Peptidylarginine deiminases as drug targets in neonatal hypoxic-ischemic encephalopathy. Frontiers in Neurology. 7 22. https://doi.org/10.3389/fneur.2016.00022
Prostate cancer cells stimulated by calcium-mediated activation of protein kinase C undergo a refractory period before re-releasing calcium-bearing microvesicles
Lange, S., Stratton, D., Moore, C., Inal, J., Zheng, L. and Li, Z. 2015. Prostate cancer cells stimulated by calcium-mediated activation of protein kinase C undergo a refractory period before re-releasing calcium-bearing microvesicles. Biochemical and Biophysical Research Communications. 460 (3), pp. 511-517. https://doi.org/10.1016/j.bbrc.2015.03.061
Microvesicles released constitutively from prostate cancer cells differ biochemically and functionally to stimulated microvesicles released through sublytic C5b-9
Lange, S., Stratton, D., Moore, C., Antwi-Baffour, S. and Inal, J. 2015. Microvesicles released constitutively from prostate cancer cells differ biochemically and functionally to stimulated microvesicles released through sublytic C5b-9. Biochemical and Biophysical Research Communications. 460 (3), p. 589–595. https://doi.org/10.1016/j.bbrc.2015.03.074
Data-driven Hippocampus CA1 Modeling in the Human Brain Project
Romani, A., Antille, N., Mercer, A., Dynes, J.A., Falk, J., Gevaert, M., Gonzalo, J.K., Kali, S., Kanari, L., Migliore, M., Lange, S., Muller, E.B., Ramaswamy, S., Reimann, M., Riquelme, R.J.L., Rössert, C.A., Shi, Y., Telefont, M., Van Geit, W.A.H., Markram, H., Thomson, A. and W.A.H. Van Geit 2015. Data-driven Hippocampus CA1 Modeling in the Human Brain Project. Neuroscience 2015. Chicago 17 Oct 2015 Society for Neuroscience.
A novel role for peptidylarginine deiminases in microvesicle release reveals therapeutic potential of PAD inhibition in sensitizing prostate cancer cells to chemotherapy
Kholia, S., Jorfi, S., Thompson, P.R., Causey, C.P., Nicholas, A.P., Inal, J. and Lange, S. 2015. A novel role for peptidylarginine deiminases in microvesicle release reveals therapeutic potential of PAD inhibition in sensitizing prostate cancer cells to chemotherapy. Journal of Extracellular Vesicles. 4 (1) 26192. https://doi.org/10.3402/jev.v4.26192
Inhibition of microvesiculation sensitizes prostate cancer cells to chemotherapy and reduces docetaxel dose required to limit tumor growth in vivo
Jorfi, S., Ansa-Addo, E.A., Kholia, S., Stratton, D., Valley, S., Lange, S. and Inal, J. 2015. Inhibition of microvesiculation sensitizes prostate cancer cells to chemotherapy and reduces docetaxel dose required to limit tumor growth in vivo. Scientific Reports. 5 (13006) 13006. https://doi.org/10.1038/srep13006
Label-free real-time acoustic sensing of microvesicle release from prostate cancer (PC3) cells using a Quartz Crystal Microbalance
Lange, S., Stratton, D., Kholia, S., Jorfi, S., Antwi-Baffour, S. and Inal, J. 2014. Label-free real-time acoustic sensing of microvesicle release from prostate cancer (PC3) cells using a Quartz Crystal Microbalance. Biochemical and Biophysical Research Communications. 453 (3), p. 619–624. https://doi.org/10.1016/j.bbrc.2014.09.132
Peptidylarginine deiminases (PADs): novel drug targets for prevention of neuronal damage following hypoxic ischemic insult (HI) in neonates
Lange, S., Rocha-Ferreira, E., Thei, L., Mawjee, P., Thompson, P.R., Nicholas, A.P., Hristova, M., Peebles, D. and Raivich, G. 2014. Peptidylarginine deiminases (PADs): novel drug targets for prevention of neuronal damage following hypoxic ischemic insult (HI) in neonates. Journal of Neurochemistry. 130 (4), pp. 555-562. https://doi.org/10.1111/jnc.12744
The Role of Infection and the TNF Family of Cytokines in Neonatal Hypoxic-Ischemic Brain Injury
Rocha-Ferreira, E., Francesch-Domenech, E., Thei, L., Rahim, A., Lange, S., Peebles, D., Hristova, M. and Raivich, G. 2014. The Role of Infection and the TNF Family of Cytokines in Neonatal Hypoxic-Ischemic Brain Injury. Reproductive Sciences. 21 (3 suppl), pp. 108A-109A. https://doi.org/10.1177/1933719114528275
Pulsed extremely low-frequency magnetic fields stimulate microvesicle release from human monocytic leukaemia cells
Lange, S., Stratton, D. and Inal, J. 2013. Pulsed extremely low-frequency magnetic fields stimulate microvesicle release from human monocytic leukaemia cells. Biochemical and Biophysical Research Communications. 430 (2), pp. 470-475. https://doi.org/10.1016/j.bbrc.2012.12.012
The Role of Deimination as a Response to Trauma and Hypoxic Injury in the Developing CNS
Ferretti, P., Lange, S., U, KP and Raivich, G. 2013. The Role of Deimination as a Response to Trauma and Hypoxic Injury in the Developing CNS. in: Nicholas, A. and Bhattacharya, S. (ed.) Protein Deimination in Human Health and Disease Springer. pp. 281-294
Blood/plasma secretome and microvesicles
Inal, J.M., Kosgodage, U., Azam, S., Stratton, D., Antwi-Baffour, S. and Lange, S. 2013. Blood/plasma secretome and microvesicles. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1834 (11), pp. 2317-2325. https://doi.org/10.1016/j.bbapap.2013.04.005
Interplay of host–pathogen microvesicles and their role in infectious disease
Inal, J.M., Ansa-Addo, E.A. and Lange, S. 2013. Interplay of host–pathogen microvesicles and their role in infectious disease. Biochemical Society Transactions. 41 (1), pp. 258-262. https://doi.org/10.1042/BST20120257
Inhibition of Protein Deimination Ameliorates Neuronal Damage Caused by Hypoxic Ischemic Insult in the Neonatal Brain
Lange, S., Rocha-Ferreira, E., Hristova, M., Thei, L., Mawjee, P., Thompson, P.R., Nicholas, T. and Raivich, G. 2013. Inhibition of Protein Deimination Ameliorates Neuronal Damage Caused by Hypoxic Ischemic Insult in the Neonatal Brain. British Neuroscience Association Abstracts. 22, pp. P1-B-071.
Microvesicles in Health and Disease
Inal, J.M., Ansa-Addo, E.A., Stratton, D., Kholia, S., Antwi-Baffour, S., Jorfi, S. and Lange, S. 2012. Microvesicles in Health and Disease. Archivum Immunologiae et Therapiae Experimentalis. 60 (2), pp. 107-121. https://doi.org/10.1007/s00005-012-0165-2
TNF gene deletion prevents lipopolysaccharide-mediated sensitisation of the neonatal mouse brain to hypoxic-ischaemic insult
Sahota, A., Kendall, G., Lange, S. and Raivich, G. 2012. TNF gene deletion prevents lipopolysaccharide-mediated sensitisation of the neonatal mouse brain to hypoxic-ischaemic insult. BMC Proceedings. 6 (Suppl 4), p. O9. https://doi.org/10.1186/1753-6561-6-S4-O9
Characterisation of microvesicles released from cells constitutively and upon stimulation
Stratton, D., Antwi-Baffour, S., Williams, G., Grant, R., Lange, S. and Inal, J.M. 2012. Characterisation of microvesicles released from cells constitutively and upon stimulation. Journal of Extracellular Vesicles. 1.
Isolation of microvesicles and exosomes by filtration and estimation of normal reference range in blood plasma
Grant, R., Ansa-Addo, E., Stratton, S., Antwi-Baffour, S., Jorfi, S., Kholia, S., Krige, L., Lange, S. and Inal, J.M. 2012. Isolation of microvesicles and exosomes by filtration and estimation of normal reference range in blood plasma. Journal of Extracellular Vesicles. 1.
The intracellular parasite, Trypanosoma cruzi, utilizes microvesicle release to invade host cells
Inal, J.M., Ansa-Addo, E., Cestari, I., Pathak, P.I., McCrossan, M.V., Lange, S. and Ramirez, M. 2012. The intracellular parasite, Trypanosoma cruzi, utilizes microvesicle release to invade host cells. Journal of Extracellular Vesicles. 1.
A filtration-based protocol to isolate human plasma membrane-derived vesicles and exosomes from blood plasma
Lange, S., Grant, R., Ansa-Addo, E.A., Stratton, D., Antwi-Baffour, S., Jorfi, S., Kholia, S., Krige, L. and Inal, J. 2011. A filtration-based protocol to isolate human plasma membrane-derived vesicles and exosomes from blood plasma. Journal of Immunological Methods. 371 (1-2), pp. 143-151. https://doi.org/10.1016/j.jim.2011.06.024
Protein deiminases: new players in the developmentally regulated loss of neural regenerative ability
Lange, S., Gogel, S., Yeung K-Y, Nicholas, A.P., Causey, C.P., Thompson, P.R., Greene, N.D.E. and Ferretti, P. 2011. Protein deiminases: new players in the developmentally regulated loss of neural regenerative ability. Developmental Biology. 355 (2), pp. 205-214. https://doi.org/10.1016/j.ydbio.2011.04.015
Post-translational regulation of CRMP in developing and regenerating chick spinal cord
Lange, S., Gogel, S., Leung Kit-Y, Greene, N.D.E. and Ferretti, P. 2010. Post-translational regulation of CRMP in developing and regenerating chick spinal cord. Developmental Neurobiology. 70 (6), pp. 456-471. https://doi.org/10.1002/dneu.20789
Human plasma membrane-derived vesicles inhibit the phagocytosis of apoptotic cells: possible role in SLE
Lange, S., Antwi-Baffour, S., Kholia, S., Ansa-Addo, E.A., Stratton, D., Aryee Y, K. and Inal, J. 2010. Human plasma membrane-derived vesicles inhibit the phagocytosis of apoptotic cells: possible role in SLE. Biochemical and Biophysical Research Communications. 398 (2), pp. 278-283. https://doi.org/10.1016/j.bbrc.2010.06.079
Human plasma membrane-derived vesicles halt proliferation and induce differentiation of THP-1 acute monocytic leukemia cells
Lange, S., Ansa-Addo, E.A., McCrossan, M.V. and Inal, J. 2010. Human plasma membrane-derived vesicles halt proliferation and induce differentiation of THP-1 acute monocytic leukemia cells. Journal of Immunology. 185 (9), pp. 5236-5246. https://doi.org/10.4049/jimmunol.1001656
Red cell PMVs, plasma membrane-derived vesicles calling out for standards
Hind, E., Heugh, S., Ansa-Addo, E.A., Antwi-Baffour, S., Lange, S. and Inal, J.M. 2010. Red cell PMVs, plasma membrane-derived vesicles calling out for standards. Biochemical and Biophysical Research Communications. 399 (4), pp. 465-469. https://doi.org/10.1016/j.bbrc.2010.07.095
Spinal cord regeneration: A role for peptidylarginine deiminase (PAD) in secondary injury response
Lange, S. 2010. Spinal cord regeneration: A role for peptidylarginine deiminase (PAD) in secondary injury response. SfN Minisymposium on Deimination in Opthalmic and Neurodegenerative diseases. San Diego Convention Center, California 16 Nov 2010
Spinal cord regeneration: peptidylarginine deiminase (PAD) and epigentic regulation of injury response
Lange, S., Ferretti, P., Goegel, S., Leung, K.T., Nicholas, A.P., Thompson, P.R. and Greene, N.D.E. 2010. Spinal cord regeneration: peptidylarginine deiminase (PAD) and epigentic regulation of injury response. FENS Forum 2010. Amsterdam 04 Jul 2010 Federation of European Neuroscience Societies.
Changes in progenitor populations and ongoing neurogenesis in the regenerating chick spinal cord
Lange, S., Whalley, K., Gogel, S. and Ferretti, P. 2009. Changes in progenitor populations and ongoing neurogenesis in the regenerating chick spinal cord. Developmental Biology. 332 (2), p. 234–245. https://doi.org/10.1016/j.ydbio.2009.05.569
Proteome changes in developing and injured chick spinal cord
Goegel, S., Lange, S., Greene, N.D.E. and Ferretti, P. 2007. Proteome changes in developing and injured chick spinal cord. Neuron Glia Biology. pp. S122-S122.
Differential gene expression following chick spinal cord injury at permissive and non permissive stages for regeneration
Lange, S., Goegel, S., Greene, N.D.E. and Ferretti, P. 2007. Differential gene expression following chick spinal cord injury at permissive and non permissive stages for regeneration. Neuron Glia Biology. pp. S121-S121.
The complement regulatory receptor CRIT is expressed in the developing kidney
Lange, S., Hui Kwok-M, Schifferli, J. and Inal, J.M. 2007. The complement regulatory receptor CRIT is expressed in the developing kidney. Molecular Immunology. 44 (16), p. 3991. https://doi.org/10.1016/j.molimm.2007.06.213
Complement C2 and CRIT are involved in the terminal differentiation of monocytes
Inal, J.M., Eva, W., Lange, S., Shamshiev, A. and Schifferli, J. 2007. Complement C2 and CRIT are involved in the terminal differentiation of monocytes. Journal of Immunology. 178, p. 83.17.
Immunostimulation of larvae and juveniles of cod, Gadus morhua L.
Lange, S., Magnadóttir, B., Gudmundsdóttir, B.K., Bambir, S.H., Steinarsson, A., Oddgeirsson, M., Bowden, T., Bricknell, I., Dalmo, R.A. and Gudmundsdottir, S. 2006. Immunostimulation of larvae and juveniles of cod, Gadus morhua L. Journal of Fish Diseases. 29 (3), p. 147–155. https://doi.org/10.1111/j.1365-2761.2006.00701.x.
CRIT is expressed on podocytes in normal human kidney and upregulated in membranous nephropathy
Lange, S., Moll, S., Mihatsch M, J., Schifferli, J. and Inal, J. 2006. CRIT is expressed on podocytes in normal human kidney and upregulated in membranous nephropathy. Kidney International. 69 (11), p. 1961–1968. https://doi.org/10.1038/sj.ki.5000379
Complement component C3 transcription in Atlantic halibut (Hippoglossus hippoglossus L.) larvae
Lange, S., Bambir, S.H., Dodds, A.W., Bowden, T., Bricknell, I., Espelid, S. and Magnadóttir, B. 2006. Complement component C3 transcription in Atlantic halibut (Hippoglossus hippoglossus L.) larvae. Fish & Shellfish Immunology. 20 (3), p. 285–294. https://doi.org/10.1016/j.fsi.2005.05.004
Complement C2 receptor inhibitor trispanning: a novel human complement inhibitory receptor
Lange, S., Inal, J., Hui Kwok-M, Miot, S., Ramirez, M., Schneider, B. and Krueger, G. 2005. Complement C2 receptor inhibitor trispanning: a novel human complement inhibitory receptor. The Journal of Immunology. 174 (1), pp. 356-366.
The ontogenic transcription of complement component C3 and Apolipoprotein A-I tRNA in Atlantic cod (Gadus morhua L.): a role in development and homeostasis?
Lange, S., Dodds, A.W., Bambir, S.H., Gudmundsdottir, S. and Magnadóttir, B. 2005. The ontogenic transcription of complement component C3 and Apolipoprotein A-I tRNA in Atlantic cod (Gadus morhua L.): a role in development and homeostasis? Developmental & Comparative Immunology. 29 (12), p. 1065–1077. https://doi.org/10.1016/j.dci.2005.03.009
The Complement Systems of Two Teleost Species with Emphasis on Ontogeny
Lange, S. 2005. The Complement Systems of Two Teleost Species with Emphasis on Ontogeny. PhD thesis University of Iceland Faculty of Medicine
Ontogeny of humoral immune parameters in fish
Magnadóttir, B., Lange, S., Gudmundsdottir, S., Bogwald, J. and Dalmo, R.A. 2005. Ontogeny of humoral immune parameters in fish. Fish and Shellfish Immunology. 19 (5), pp. 429-439. https://doi.org/10.1016/j.fsi.2005.03.010
The ontogeny of complement component C3 in Atlantic cod (Gadus morhua L.)—an immunohistochemical study
Lange, S., Bambir, S., Dodds, A.W. and Magnadóttir, B. 2004. The ontogeny of complement component C3 in Atlantic cod (Gadus morhua L.)—an immunohistochemical study. Fish & Shellfish Immunology. 16 (3), pp. 359-367. https://doi.org/10.1016/j.fsi.2003.06.001
Is Apolipoprotein A-I a regulating protein for the complement system of cod (Gadus morhua L.)?
Magnadóttir, B. and Lange, S. 2004. Is Apolipoprotein A-I a regulating protein for the complement system of cod (Gadus morhua L.)? Fish and Shellfish Immunology. 16 (2), pp. 265-269. https://doi.org/10.1016/S1050-4648(03)00061-5
Isolation and characterization of complement component C3 from Atlantic cod (Gadus morhua L.) and Atlantic halibut (Hippoglossus hippoglossus L.)
Lange, S., Dodds, A.W. and Magnadóttir, B. 2004. Isolation and characterization of complement component C3 from Atlantic cod (Gadus morhua L.) and Atlantic halibut (Hippoglossus hippoglossus L.). Fish and Shellfish Immunology. 16 (2), pp. 227-239. https://doi.org/10.1016/S1050-4648(03)00081-0
Spontaneous haemolytic activity of Atlantic halibut (Hippoglossus hippoglossus L.) and sea bass (Dicentrarchus labrax) serum
Lange, S. and Magnadóttir, B. 2003. Spontaneous haemolytic activity of Atlantic halibut (Hippoglossus hippoglossus L.) and sea bass (Dicentrarchus labrax) serum. Comparative Biochemistry and Physiology - Part B: Biochemistry & Molecular Biology. 136 (1), pp. 99-106. https://doi.org/10.1016/S1096-4959(03)00173-8
Protection against atypical furunculosis in Atlantic halibut, Hippoglossus hippoglossus (L.); comparison of a commercial furunculosis vaccine and an autogenous vaccine
Gudmundsdottir, S., Lange, S., Magnadóttir, B. and Gudmundsdóttir, B.K. 2003. Protection against atypical furunculosis in Atlantic halibut, Hippoglossus hippoglossus (L.); comparison of a commercial furunculosis vaccine and an autogenous vaccine. Journal of Fish Diseases. 26 (6), pp. 331-338. https://doi.org/10.1046/j.1365-2761.2003.00462.x
Humoral immune parameters of cultured Atlantic halibut (Hippoglossus hippoglossus L.)
Lange, S., Guđmundsdottir, B.K. and Magnadóttir, B. 2001. Humoral immune parameters of cultured Atlantic halibut (Hippoglossus hippoglossus L.). Fish and Shellfish Immunology. 11 (6), pp. 523-535. https://doi.org/10.1006/fsim.2000.0333
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