Neuroblastoma: Anti‐Invasive Effects of Tetracaine In Vitro*

Mumio Potentiates Temozolomide by Inducing Apoptosis and Ferroptosis in Glioblastoma Cells
Basak Dalbayrak, Zeynep Demirel, Ayşe Şevval Martin, Pınar Uysal Onganer, Pinar Obakan Yerlikaya, Sedat Dalbayrak and Elif Damla Arisan 2026. Mumio Potentiates Temozolomide by Inducing Apoptosis and Ferroptosis in Glioblastoma Cells. Current Pharmaceutical Design. Advanced online publication. https://doi.org/10.2174/0113816128484031260604055912

Oleuropein Attenuates 6-Hydroxydopamine-Induced Cytotoxicity Through Redox Regulation in Differentiated Dopaminergic Neurons: Potential Involvement of RET-Associated Signalling
Ahmed, B.Y., Lange, S., Warda, M., Shadidizaji, A. and Uysal Onganer, P. 2026. Oleuropein Attenuates 6-Hydroxydopamine-Induced Cytotoxicity Through Redox Regulation in Differentiated Dopaminergic Neurons: Potential Involvement of RET-Associated Signalling. International Journal of Molecular Sciences. 27 (13), p. 5892 5892. https://doi.org/10.3390/ijms27135892

Non-coding RNAs as biomarkers and therapeutic targets in pancreatic cancer: Clinical implications and translational perspectives
Uysal Onganer, P. 2026. Non-coding RNAs as biomarkers and therapeutic targets in pancreatic cancer: Clinical implications and translational perspectives. Biomedicine & Pharmacotherapy. 199 119394. https://doi.org/10.1016/j.biopha.2026.119394

EBV BART microRNA Profiles and Host Gene Links in Gastric Cancer
Dirimtekin, E., Dart, D.A. and Uysal Onganer, P. 2026. EBV BART microRNA Profiles and Host Gene Links in Gastric Cancer. Viruses. 18 (3) 329. https://doi.org/10.3390/v18030329

Chemopreventive Effects of Lycopene in miR‐21 Knockout and Wild‐Type Pancreatic Cancer Cells
Basak Dalbayrak, Burcu Taluğ Taştan, Tuğçe Temel, Pinar Obakan Yerlikaya, Pinar Uysal Onganer and Elif Damla Arisan 2026. Chemopreventive Effects of Lycopene in miR‐21 Knockout and Wild‐Type Pancreatic Cancer Cells. Scientifica. 2026 (1) 865270. https://doi.org/10.1155/sci5/8865270

Profiling Protein Citrullination in Extracellular Vesicles by Single‐Molecule Detection Using Direct Stochastic Optical Reconstruction Microscopy
Needham, S.R., Davis, B.M., Uysal Onganer, P., Rolfe, D.J., Hristova, M., Kraev, I., Inal, J. and Lange, S. 2026. Profiling Protein Citrullination in Extracellular Vesicles by Single‐Molecule Detection Using Direct Stochastic Optical Reconstruction Microscopy. Journal of Biophotonics. 19 (3) e202500483. https://doi.org/10.1002/jbio.202500483

Profiling Protein Citrullination in Extracellular Vesicles by Single-Molecule Detection Using Direct Stochastic Optical Reconstruction Microscopy
Needham, S.R., Davis, B.M., Uysal Onganer, P., Rolfe, D.J., Hristova, M., Kraev, I., Inal, J.M. and Lange, S. 2025. Profiling Protein Citrullination in Extracellular Vesicles by Single-Molecule Detection Using Direct Stochastic Optical Reconstruction Microscopy. Journal of Biophotonics. 2025 e202500483. https://doi.org/10.1002/jbio.202500483

Boron‐Enhanced Mitochondrial Repair: DeepA‐I Tissue Regeneration
Beyza Yılmaz, Basak Dalbayrak, Mustafa Kucukali, Pinar Uysal Onganer and Elif Damla Arısan 2025. Boron‐Enhanced Mitochondrial Repair: DeepA‐I Tissue Regeneration. Scientifica. Advanced online publication. https://doi.org/10.1155/sci5/5343930

Perineural Invasion in Pancreatic Ductal Adenocarcinoma: Recapitulating Its Importance and Defining Future Directions
Martin Lovecek, Esra Dirimtekin, Ingrid Garajová, Giulia Gasparini, Stefano Crippa, Elisa Giovannetti, Dana Sochorova, Carmen Mota Reyes, Ihsan Ekin Demir and Pinar Uysal‐Onganer 2025. Perineural Invasion in Pancreatic Ductal Adenocarcinoma: Recapitulating Its Importance and Defining Future Directions. United European Gastroenterology Journal. 13 (9), pp. 1678-1689. https://doi.org/10.1002/ueg2.70118

Hypoxia-Driven Extracellular Vesicles Promote Pro-Metastatic Signalling in LNCaP Cells via Wnt and EMT Pathways
Melissa Santos, Khansa Bukhari, Irem Peker-Eyüboğlu, Igor Kraev, Dafydd Alwyn Dart, Sigrun Lange and Pinar Uysal-Onganer 2025. Hypoxia-Driven Extracellular Vesicles Promote Pro-Metastatic Signalling in LNCaP Cells via Wnt and EMT Pathways. Biology. 14 (9) 1135. https://doi.org/10.3390/biology14091135

Immune Tuning in Extreme Environments: Protein Citrullinome and Extracellular Vesicle Signatures Comparing Hibernating Versus Active States in the Heterothermic and Heterometabolic Tenrec (Tenrec ecaudatus)
Gilbecca Rae Smith, Pinar Uysal-Onganer, Igor Kraev, Frank van Breukelen and Sigrun Lange 2025. Immune Tuning in Extreme Environments: Protein Citrullinome and Extracellular Vesicle Signatures Comparing Hibernating Versus Active States in the Heterothermic and Heterometabolic Tenrec (Tenrec ecaudatus). Biology. 14 1056. https://doi.org/10.3390/biology14081056

From Hypoxia to Bone: Reprogramming the Prostate Cancer Metastatic Cascade
Melissa Santos, Sarah Koushyar, Dafydd Alwyn Dart and Pinar Uysal-Onganer 2025. From Hypoxia to Bone: Reprogramming the Prostate Cancer Metastatic Cascade. International Journal of Molecular Sciences. 26 (15) 7452. https://doi.org/10.3390/ijms26157452

The exposome and pancreatic cancer, lifestyle and environmental risk factors for PDAC
Giulia Peduzzi, Livia Archibugi, Riccardo Farinella, Ruggero Ponz de Leon Pisani b ,, Ludmila Vodickova, Pavel Vodicka, Bledar Kraja, Juan Sainz, David Bars-Cortina, Neil Daniel, Roberto Silvestri, Pinar Uysal Onganer, Stefano Landi, Joanna Dulińska-Litewka, Annalisa Comandatore, Daniele Campa, David J. Hughes and Cosmeri Rizzato 2025. The exposome and pancreatic cancer, lifestyle and environmental risk factors for PDAC. Seminars in Cancer Biology. 113, pp. 100-129. https://doi.org/10.1016/j.semcancer.2025.05.004

Targeting Methionine Metabolism Reveals AMPK-SAMTOR Signaling as a Therapeutic Vulnerability in Prostate Cancer
Arisan, S., Sever, A., Obakan Yerlikaya, P., Arisan, E. and Uysal Onganer, P. 2025. Targeting Methionine Metabolism Reveals AMPK-SAMTOR Signaling as a Therapeutic Vulnerability in Prostate Cancer. Biology. 14 (5) 507. https://doi.org/10.3390/biology14050507

Biomarkers, Omics and Artificial Intelligence for Early Detection of Pancreatic Cancer
Murray, Kate, Oldfield, Lucy, Stefanova, Irena, Gentiluomo, Manuel, Aretini, Paolo, O’Sullivan, Rachel, Greenhalf, William, Paiella, Salvatore, Aoki, Mateus N, Pastore, Aldo, Birch-Ford, James, Rao, Bhavana Hemantha, Uysal-Onganer, Pinar, Walsh, Caoimhe M, Hanna, George B, Narang, Jagriti, Sharma, Pradakshina, Campa, Daniele, Rizzato, Cosmeri, Turtoi, Andrei, Sever, Elif Arik, Felici, Alessio, Sucularli, Ceren, Peduzzi, Giulia, Öz, Elif, Sezerman, Osman Uğur, Van der Meer, Robert, Thompson, Nathan and Costello, Eithne 2025. Biomarkers, Omics and Artificial Intelligence for Early Detection of Pancreatic Cancer. Seminars in Cancer Biology. 111, pp. 76-88. https://doi.org/10.1016/j.semcancer.2025.02.009

miR-210 Mediated Hypoxic Responses in Pancreatic Ductal Adenocarcinoma
Mortoglou, M., Lian, M., Miralles, F., Dart, D.A. and Uysal Onganer, P. 2024. miR-210 Mediated Hypoxic Responses in Pancreatic Ductal Adenocarcinoma. ACS Omega. 9 (48), pp. 47872-47883. https://doi.org/10.1021/acsomega.4c08947

Extracellular vesicles and citrullination signatures are novel biomarkers in sturgeon (Acipenser gueldenstaedtii) during chronic stress due to seasonal temperature challenge
Ferreira, A.M., Silva-Álvarez, V., Kraev, I., Uysal Onganer, P. and Lange, S. 2024. Extracellular vesicles and citrullination signatures are novel biomarkers in sturgeon (Acipenser gueldenstaedtii) during chronic stress due to seasonal temperature challenge. Fish and Shellfish Immunology. 154 (8), p. 109974 109974. https://doi.org/10.1016/j.fsi.2024.109974

Low Magnetic Field Exposure Alters Prostate Cancer Cell Properties
Lange, S., Inal, J.M., Kraev, I., Dart, D. and Uysal Onganer, P. 2024. Low Magnetic Field Exposure Alters Prostate Cancer Cell Properties. Biology. 13 (9), p. 734 13090734. https://doi.org/10.3390/biology13090734

Exploring the potential link between prostate cancer and magnetic fields
Alwyn Dart, D., Koushyar, S. and Uysal Onganer, P. 2024. Exploring the potential link between prostate cancer and magnetic fields. Medical Hypotheses. 189 111384. https://doi.org/10.1016/j.mehy.2024.111384

Analysis of androgen receptor expression and activity in the mouse brain
D. Alwyn Dart, Charlotte L. Bevan, Pinar Uysal Onganer and Wen Guo Jiang 2024. Analysis of androgen receptor expression and activity in the mouse brain. Scientific Reports. 14 11115. https://doi.org/10.1038/s41598-024-61733-9

BRCA Mutations and MicroRNA Expression Patterns in the Peripheral Blood of Breast Cancer Patients
Alavanda, Ceren, Dirimtekin, Esra, Mortoglou, Maria, Uysal Onganer, Pinar, Arslan Ates, Esra and Guney, Ahmet Ilter 2024. BRCA Mutations and MicroRNA Expression Patterns in the Peripheral Blood of Breast Cancer Patients. ACS Omega. 9 (15), pp. 17217-17228. https://doi.org/10.1021/acsomega.3c10086

Impact of Hypoxia-Induced miR-210 on Pancreatic Cancer
Lian, M., Mortoglou, M. and Uysal Onganer, P. 2023. Impact of Hypoxia-Induced miR-210 on Pancreatic Cancer. Current Issues in Molecular Biology. 45 (12), pp. 9778-9792. https://doi.org/10.3390/cimb45120611

miR-34a-FOXP1 Loop in Ovarian Cancer
Dirimtekin, E., Mortoglou, M., Alavanda, C., Yemlahi, A.B., Ates, E.A., Guney, I. and Uysal Onganer, P. 2023. miR-34a-FOXP1 Loop in Ovarian Cancer. ACS Omega. 8 (30), pp. 27743-27750. https://doi.org/10.1021/acsomega.3c03867

Prohibitin Links Cell Cycle, Motility and Invasion in Prostate Cancer Cells
Koushyar, S., Uysal Onganer, P., Jiang, W.G. and Dart , D.A. 2023. Prohibitin Links Cell Cycle, Motility and Invasion in Prostate Cancer Cells. International Journal of Molecular Sciences. 24 (12) 9919. https://doi.org/10.3390/ijms24129919

The Use of Plant Steroids in Viral Disease Treatments: Current Status and Future Perspectives
Obakan Yerlikaya, P., Arisan, E.D., Mehdizadehtapeh, L., Uysal Onganer, P. and Coker-Gurkan, A. 2023. The Use of Plant Steroids in Viral Disease Treatments: Current Status and Future Perspectives. European Journal of Biology. 82 (1), pp. 86-94. https://doi.org/10.26650/EurJBiol.2023.1130357

Inhibiting CDK4/6 in pancreatic ductal adenocarcinoma via microRNA-21
Mortoglou, M., Miralles, F., Mould, R., Sengupta, D. and Uysal Onganer, P. 2023. Inhibiting CDK4/6 in pancreatic ductal adenocarcinoma via microRNA-21. European Journal of Cell Biology. 102 (2) 151318. https://doi.org/10.1016/j.ejcb.2023.151318

Circulating microRNA expression profiles to identify a potential link between prostate cancer and obesity
Arisan, Serdar, Ozfiliz-Kilbas, Pelin, Rencuzogullari, Ozge, Unsal, Narcin Palavan, Coker-Gurkan, Ajda, Obakan-Yerlikaya, Pinar, Uysal-Onganer, Pinar and Arisan, Elif Damla 2022. Circulating microRNA expression profiles to identify a potential link between prostate cancer and obesity. Human Gene. 34 201109. https://doi.org/10.1016/j.humgen.2022.201109

microRNA 1307 Is a Potential Target for SARS-CoV-2 Infection: An <i>in Vitro</i> Model
Arisan, Elif Damla, Dart, D. Alwyn, Grant, Guy H., Dalby, A.R., Kancagi, Derya Dilek, Turan, Raife Dilek, Yurtsever, Bulut, Karakus, Gozde Sir, Ovali, Ercument, Lange, Sigrun and Uysal-Onganer, P. 2022. microRNA 1307 Is a Potential Target for SARS-CoV-2 Infection: An <i>in Vitro</i> Model. ACS Omega. 7 (42), pp. 38003-38014. https://doi.org/10.1021/acsomega.2c05245

3D Disease Modelling of Hard and Soft Cancer Using PHA-Based Scaffolds
Tomar, A., Uysal-Onganer, P., Basnett, P., Pati, U. and Roy, I. 2022. 3D Disease Modelling of Hard and Soft Cancer Using PHA-Based Scaffolds. Cancers. 14 (14) e3549. https://doi.org/10.3390/cancers14143549

microRNA expression in acute myeloid leukaemia: New targets for therapy?
Fletcher, D., Brown, E., Javadala, J., Uysal Onganer, P. and Guinn, B-A. 2022. microRNA expression in acute myeloid leukaemia: New targets for therapy? European Journal of Haemotology. 3 (3), pp. 596-608. https://doi.org/10.1002/jha2.441

Epigenetic Mechanisms of Metal Carcinogenicity
Manić, L., Wallace, D., Uysal Onganer, P., Taalab, Y.M., Farooqi, A.A., Antonijević, B. and Djordjevic, A.B. 2022. Epigenetic Mechanisms of Metal Carcinogenicity. Toxicology Reports. 9, pp. 778-787. https://doi.org/10.1016/j.toxrep.2022.03.037

Nickel's Role in Pancreatic Ductal Adenocarcinoma: Potential Involvement of microRNAs
Mortoglou, M., Manić, L., Buha Djordjevic, A., Bulat, Z., Đorđević, Vladimir, Manis, Katherine, Valle, Elizabeth, York, Lauren, Wallace, D. and Uysal Onganer, P. 2022. Nickel's Role in Pancreatic Ductal Adenocarcinoma: Potential Involvement of microRNAs. Toxics. 10 (3) 148. https://doi.org/10.3390/toxics10030148

microRNA-21 Regulates Stemness in Pancreatic Ductal Adenocarcinoma Cells
Mortoglou, M., Miralles, F., Arisan, E.D., Dart, A., Jurcevic, S., Lange, S. and Uysal Onganer, P. 2022. microRNA-21 Regulates Stemness in Pancreatic Ductal Adenocarcinoma Cells. International Journal of Molecular Sciences. 23 (3) 1275. https://doi.org/10.3390/ijms23031275

Role of microRNAs in response to cadmium chloride in pancreatic ductal adenocarcinoma
Mortoglou, M., Djordjevic, A.B., Djordjevic, V., Collins, H., York, L., Mani, K., Valle, E., Wallace, D. and Uysal Onganer, P. 2021. Role of microRNAs in response to cadmium chloride in pancreatic ductal adenocarcinoma. Archives of Toxicology. 96, p. 467–485. https://doi.org/10.1007/s00204-021-03196-9

The Role of CDK4 in the Pathogenesis of Pancreatic Cancer.
Jiggens, E., Mortoglou, M., Grant, G.H. and Uysal-Onganer, P. 2021. The Role of CDK4 in the Pathogenesis of Pancreatic Cancer. Healthcare. 9 (11) 1478. https://doi.org/10.3390/healthcare9111478

In Vitro Investigations of miR-33a Expression in Estrogen Receptor-Targeting Therapies in Breast Cancer Cells
Ozfiliz Kilbas, P., Ozlem Sonmez, Pinar Obakan-Yerlikaya, Ajda Coker-Gurkan, Narcin Palavan-Ünsal, Uysal Onganer, P. and Arisan, E. 2021. In Vitro Investigations of miR-33a Expression in Estrogen Receptor-Targeting Therapies in Breast Cancer Cells. Cancers. 13 (21), p. e5322. https://doi.org/10.3390/cancers13215322

Prostate Cancer Cell Extracellular Vesicles Increase Mineralisation of Bone Osteoblast Precursor Cells in an In Vitro Model
Ben Lanning, Webber, J., Uysal Onganer, P., Jiang, W., Aled Clayton and Dart, D. 2021. Prostate Cancer Cell Extracellular Vesicles Increase Mineralisation of Bone Osteoblast Precursor Cells in an In Vitro Model. Biology. 10 (4) 318. https://doi.org/10.3390/biology10040318

AMPK Is the Crucial Target for the CDK4/6 Inhibitors Mediated Therapeutic Responses in PANC-1 and MIA PaCa-2 Pancreatic Cancer Cell Lines
Sevgin, B., Coban, M., Özge Rencuzogullari, Coker Gurkan, A., Obakan Yerlikaya, P., Uysal Onganer, P. and Arisan, E. 2021. AMPK Is the Crucial Target for the CDK4/6 Inhibitors Mediated Therapeutic Responses in PANC-1 and MIA PaCa-2 Pancreatic Cancer Cell Lines. Stresses. 1 (1), pp. 48-68. https://doi.org/10.3390/stresses1010005

MicroRNA-Regulated Signaling Pathways: Potential Biomarkers for Pancreatic Ductal Adenocarcinoma
Mortoglou, M., Wallace, D., Buha Djordjevic, A., Vladimir Djordjevic, Arisan, E. and Uysal Onganer, P. 2021. MicroRNA-Regulated Signaling Pathways: Potential Biomarkers for Pancreatic Ductal Adenocarcinoma. Stresses. 1 (1), pp. 30-47. https://doi.org/10.3390/stresses1010004

MiR-21 Is Required for the Epithelial–Mesenchymal Transition in MDA-MB-231 Breast Cancer Cells
Arisan, E., Rencuzogullari, O., Clara Cieza-Borrella, Miralles Arenas, F., Miriam Dwek, Lange, S. and Uysal Onganer, P. 2021. MiR-21 Is Required for the Epithelial–Mesenchymal Transition in MDA-MB-231 Breast Cancer Cells. International Journal of Molecular Sciences. 22 (4), p. e1557 1557. https://doi.org/10.3390/ijms22041557

Peptidylarginine Deiminase Inhibitor Application, Using Cl-Amidine, PAD2, PAD3 and PAD4 Isozyme-Specific Inhibitors in Pancreatic Cancer Cells, Reveals Roles for PAD2 and PAD3 in Cancer Invasion and Modulation of Extracellular Vesicle Signatures
Uysal Onganer, P., D'alessio, S., Mortoglou, M., Kraev, I. and Lange, S. 2021. Peptidylarginine Deiminase Inhibitor Application, Using Cl-Amidine, PAD2, PAD3 and PAD4 Isozyme-Specific Inhibitors in Pancreatic Cancer Cells, Reveals Roles for PAD2 and PAD3 in Cancer Invasion and Modulation of Extracellular Vesicle Signatures. International Journal of Molecular Sciences. 22 (3) 1396. https://doi.org/10.3390/ijms22031396

MicroRNAs for Virus Pathogenicity and Host Responses, Identified in SARS-CoV-2 Genomes, May Play Roles in Viral-Host Co-Evolution in Putative Zoonotic Host Species
Lange, S., Arisan, E.D., Grant, G.H. and Uysal Onganer, P. 2021. MicroRNAs for Virus Pathogenicity and Host Responses, Identified in SARS-CoV-2 Genomes, May Play Roles in Viral-Host Co-Evolution in Putative Zoonotic Host Species. MDPI Viruses. 13 (1), p. 117 10.3390/v13010117 . https://doi.org/10.3390/v13010117

Elevated microRNA expression could be diagnostic biomarker for PDAC
Mortoglou, M., Arisan, D., Ferreira, T., McCormick, A.L. and Uysal Onganer, P. 2020. Elevated microRNA expression could be diagnostic biomarker for PDAC. Pancreatology. 20 (8) e19. https://doi.org/10.1016/j.pan.2020.10.015

Specific c-Jun N-Terminal Kinase Inhibitor, JNK-IN-8 Suppresses Mesenchymal Profile of PTX-Resistant MCF-7 Cells through Modulating PI3K/Akt, MAPK and Wnt Signaling Pathways
Ozfiliz Kilbas, P., Sonmez, Ozlem, Uysal Onganer, P., Coker Gurkan, A., Obakan Yerlikaya, P. and Arisan, Elif Damla 2020. Specific c-Jun N-Terminal Kinase Inhibitor, JNK-IN-8 Suppresses Mesenchymal Profile of PTX-Resistant MCF-7 Cells through Modulating PI3K/Akt, MAPK and Wnt Signaling Pathways. Biology. 9 (10), p. e320. https://doi.org/10.3390/biology9100320

Inhibition on JNK Mimics Silencing of Wnt-11 Mediated Cellular Response in Androgen-Independent Prostate Cancer Cells
Elif Damla Arisan, Ozge Rencuzogullari, Buse Keskin, Guy H. Grant and Pinar Uysal Onganer 2020. Inhibition on JNK Mimics Silencing of Wnt-11 Mediated Cellular Response in Androgen-Independent Prostate Cancer Cells. Biology. 9 (7) 142. https://doi.org/10.3390/biology9070142

Putative Roles for Peptidylarginine Deiminases in COVID-19
Arisan, E., Uysal Onganer, P. and Lange, S. 2020. Putative Roles for Peptidylarginine Deiminases in COVID-19. International Journal of Molecular Sciences. 21 (13) 4662. https://doi.org/10.3390/ijms21134662

The Prediction of miRNAs in SARS-CoV-2 Genomes: hsa-miR Databases Identify 7 Key miRs Linked to Host Responses and Virus Pathogenicity-Related KEGG Pathways Significant for Comorbidities
Arisan, E.D., Dart, A., Grant, G.H., Arisan, S., Cuhadaroglu, S., Lange, S. and Uysal Onganer, P. 2020. The Prediction of miRNAs in SARS-CoV-2 Genomes: hsa-miR Databases Identify 7 Key miRs Linked to Host Responses and Virus Pathogenicity-Related KEGG Pathways Significant for Comorbidities. MDPI Viruses. 12 (6) 614. https://doi.org/10.3390/v12060614

Protein Deimination Signatures in Plasma and Plasma-EVs and Protein Deimination in the Brain Vasculature in a Rat Model of Pre-Motor Parkinson’s Disease
Marco Sancandi, Uysal Onganer, P., Igor Kraev, Mercer, A. and Lange, S. 2020. Protein Deimination Signatures in Plasma and Plasma-EVs and Protein Deimination in the Brain Vasculature in a Rat Model of Pre-Motor Parkinson’s Disease. International Journal of Molecular Sciences. 21 (8) 2743. https://doi.org/10.3390/ijms21082743

Demonstration of microRNA using in situ hybridisation on formalin fixed paraffin wax samples using conventional oligonucleotide probes: a comparison with the use of locked nucleic acid probes
Warford, A., Rahman, N.S., Ribeiro, D.A. and Uysal Onganer, P. 2020. Demonstration of microRNA using in situ hybridisation on formalin fixed paraffin wax samples using conventional oligonucleotide probes: a comparison with the use of locked nucleic acid probes. British Journal of Biomedical Science. 77 (3), pp. 135-141. https://doi.org/10.1080/09674845.2020.1748913

The Role of Differentially Expressed miRNAs and Potential miRNA-mRNA Regulatory Network in Prostate Cancer Progression and Metastasis
Arisan, E.D., Freitas, I.L., Pazoki, K., Rahim, S. and Uysal Onganer, P. 2020. The Role of Differentially Expressed miRNAs and Potential miRNA-mRNA Regulatory Network in Prostate Cancer Progression and Metastasis. Biomedical Journal of Technical and Scientific Research. 25 (4), pp. 19382-19387. https://doi.org/10.26717/BJSTR.2020.25.004241

Upregulated wnt-11 and mir-21 expression trigger epithelial mesenchymal transition in aggressive prostate cancer cells
Arisan, E.D., Rencuzogullari, O., Freitas, I.L., Radzali, S., Keskin, B., Kothari, A., Warford, A. and Uysal-Onganer, P. 2020. Upregulated wnt-11 and mir-21 expression trigger epithelial mesenchymal transition in aggressive prostate cancer cells. Biology. 9 (3) 52. https://doi.org/10.3390/biology9030052

Deiminated Proteins and Extracellular Vesicles as Novel Biomarkers in Pinnipeds: Grey seal (Halichoerus gryptus) and Harbour seal (Phoca vitulina)
Magnadóttir, B., Uysal Onganer, P., Kraev, I., Svansson, V., Skírnisson, K. and Lange, S. 2020. Deiminated Proteins and Extracellular Vesicles as Novel Biomarkers in Pinnipeds: Grey seal (Halichoerus gryptus) and Harbour seal (Phoca vitulina). Biochimie . 171-172, pp. 79-90. https://doi.org/10.1016/j.biochi.2020.02.017

Peptidylarginine Deiminase Isozyme-Specific PAD2, PAD3 and PAD4 Inhibitors Differentially Modulate Extracellular Vesicle Signatures and Cell Invasion in Two Glioblastoma Multiforme Cell Lines
Uysal Onganer, P., Amy MacLatchy, Rayan Mahmoud, Kraev, I., Paul R. Thompson, Jameel M. Inal and Lange, S. 2020. Peptidylarginine Deiminase Isozyme-Specific PAD2, PAD3 and PAD4 Inhibitors Differentially Modulate Extracellular Vesicle Signatures and Cell Invasion in Two Glioblastoma Multiforme Cell Lines. International Journal of Molecular Sciences. 21 (4) 1495. https://doi.org/10.3390/ijms21041495

Deiminated proteins and extracellular vesicles - Novel serum biomarkers in whales and orca
Magnadóttir, B., Uysal-Onganer, P., Kraev, I., Svansson, V., Hayes, P.M. and Lange, S. 2020. Deiminated proteins and extracellular vesicles - Novel serum biomarkers in whales and orca. Comparative Biochemistry and Physiology - Part D: Genomics and Proteomics. 34, p. 100676 100676. https://doi.org/10.1016/j.cbd.2020.100676

Extracellular Vesicles, Deiminated Protein Cargo and microRNAs are Novel Serum Biomarkers for Environmental Rearing Temperature in Atlantic Cod (Gadus morhua L.)
Magnadóttir, B., Uysal Onganer, P., Kraev, I., Dodds, A.W., Gudmundsdottir, S. and Lange, S. 2020. Extracellular Vesicles, Deiminated Protein Cargo and microRNAs are Novel Serum Biomarkers for Environmental Rearing Temperature in Atlantic Cod (Gadus morhua L.) . Aquaculture Reports. 16 100245. https://doi.org/10.1016/j.aqrep.2019.100245

Wnt-11 expression promotes invasiveness and correlates with survival in human pancreatic ductal adeno carcinoma
Dart, D.A., Arisan, D.E., Owen, S., Hao, C., Jiang, W.G. and Uysal-Onganer, P. 2019. Wnt-11 expression promotes invasiveness and correlates with survival in human pancreatic ductal adeno carcinoma. Genes. 10 (11) 921. https://doi.org/10.3390/genes10110921

Post-Translational Deimination of Immunological and Metabolic Protein Markers in Plasma and Extracellular Vesicles of Naked Mole-Rat (Heterocephalus glaber)
Matthew E. Pamenter, Uysal Onganer, P., Kenny W. Huynh, Kraev, I. and Lange, S. 2019. Post-Translational Deimination of Immunological and Metabolic Protein Markers in Plasma and Extracellular Vesicles of Naked Mole-Rat (Heterocephalus glaber). International Journal of Molecular Sciences. 20 (21) 5378. https://doi.org/10.3390/ijms20215378

Peptidylarginine Deiminases Post-translationally deiminate Prohibitin and modulate Extracellular Vesicle Release and microRNAs in Glioblastoma Multiforme
Kosgodage, U., Uysal Onganer, P., Maclatchy, A., Kraev, I., Chatterton, N.P., Nicholas, A.P., Inal, J.M. and Lange, S. 2019. Peptidylarginine Deiminases Post-translationally deiminate Prohibitin and modulate Extracellular Vesicle Release and microRNAs in Glioblastoma Multiforme . International Journal of Molecular Sciences. 20 (1) 103. https://doi.org/10.3390/ijms20010103

Cannabidiol Affects Extracellular Vesicle Release, miR21 and miR126, and Reduces Prohibitin Protein in Glioblastoma Multiforme Cells
Kosgodage, U., Uysal Onganer, P., Maclatchy, A., Mould, R., Nunn, A.V.W., Guy, G.W., Kraev, I., Chatterton, N.P., Thomas, E.L., Inal, J.M., Bell, J.D. and Lange, S. 2019. Cannabidiol Affects Extracellular Vesicle Release, miR21 and miR126, and Reduces Prohibitin Protein in Glioblastoma Multiforme Cells. Translational Oncology. 12 (3), pp. 513-522. https://doi.org/10.1016/j.tranon.2018.12.004

Prostate-specific PTen deletion in mice activates inflammatory microRNA expression pathways in the epithelium early in hyperplasia development
Dart Alwyn, D., Uysal-Onganer, P. and Jiang, W.G. 2017. Prostate-specific PTen deletion in mice activates inflammatory microRNA expression pathways in the epithelium early in hyperplasia development. Oncogenesis. 14 (6) 400. https://doi.org/10.1038/s41389-017-0007-5

The interaction of Wnt-11 and signalling cascades in prostate cancer
Koushyar, S., Grant, G.H. and Uysal-Onganer, P. 2016. The interaction of Wnt-11 and signalling cascades in prostate cancer. Tumor Biology. 37 (10), pp. 13049-13057. https://doi.org/10.1007/s13277-016-5263-z

Distinct expression and activity of GSK-3α and GSK-3β in prostate cancer
Darrington, R.S., Campa, V.M., Walker, M.M., Bengoa-Vergniory, N., Gorrono-Etxebarria, I., Uysal-Onganer, P., Kawano, Y., Waxman, J. and Kypta, R.M. 2012. Distinct expression and activity of GSK-3α and GSK-3β in prostate cancer. International Journal of Cancer. 131 (6), p. E872–E883. https://doi.org/10.1002/ijc.27620

Secreted Frizzled-related protein-1 is a negative regulator of androgen receptor activity in prostate cancer
Kawano, Y., Diez, S., Uysal-Onganer, P., Darrington, R.S., Waxman, J. and Kypta, R.M. 2009. Secreted Frizzled-related protein-1 is a negative regulator of androgen receptor activity in prostate cancer. British Journal of Cancer. 100, pp. 1165-1174. https://doi.org/10.1038/sj.bjc.6604976

Epidermal growth factor upregulates motility of Mat-LyLu rat prostate cancer cells partially via voltage-gated Na+ channel activity
Ding, Y., Brackenbury, W.J., Uysal Onganer, P., Montano, Ximena, Porter, L.M., Bates, L.F. and Djamgoz, M.B.A. 2008. Epidermal growth factor upregulates motility of Mat-LyLu rat prostate cancer cells partially via voltage-gated Na+ channel activity. Journal of Cellular Physiology. 215 (1), pp. 77-81. https://doi.org/10.1002/jcp.21289

The expression and functional characterization of sigma (sigma) 1 receptors in breast cancer cell lines
Aydar, E., Uysal Onganer, P., Perrett, R., Djamgoz, M.B.A. and Palmer, C.P. 2006. The expression and functional characterization of sigma (sigma) 1 receptors in breast cancer cell lines. Cancer Letters. 242 (2), pp. 245-257. https://doi.org/10.1016/j.canlet.2005.11.011

An acetylcholinesterase-derived peptide inhibits endocytic membrane activity in a human metastatic breast cancer cell line
Uysal Onganer, P., Djamgoz, M.B.A., Whyte, K. and Greenfield, S.A. 2006. An acetylcholinesterase-derived peptide inhibits endocytic membrane activity in a human metastatic breast cancer cell line. Biochimica et Biophysica Acta: general subjects. 1760 (3), pp. 415-420. https://doi.org/10.1016/j.bbagen.2005.12.016

Small-cell lung cancer (human): potentiation of endocytic membrane activity by voltage-gated Na(+) channel expression in vitro
Uysal Onganer, P. and Djamgoz, M.B.A. 2005. Small-cell lung cancer (human): potentiation of endocytic membrane activity by voltage-gated Na(+) channel expression in vitro. Journal of Membrane Biology. 204, pp. 67-75. https://doi.org/10.1007/s00232-005-0747-6

Neuronal characteristics of small-cell lung cancer
Uysal Onganer, P., Seckl, M.J. and Djamgoz, M.B.A. 2005. Neuronal characteristics of small-cell lung cancer. British Journal of Cancer. 93, pp. 1197-1201. https://doi.org/10.1038/sj.bjc.6602857

Genotypes of the hepatitis B virus: basic aspects
Uysal Onganer, P. 2004. Genotypes of the hepatitis B virus: basic aspects. Annals of Microbiology. 54 (3), pp. 325-334.