Biomedical Sciences

Elliott, B., Renshaw, D., Getting, S.J. and MacKenzie, R. 2012. The central role of myostatin in skeletal muscle and whole body homeostasis. Acta Physiologica. 205 (3), pp. 324-40. https://doi.org/10.1111/j.1748-1716.2012.02423.x

Iqbal, H.M.N., Tron, T. and Keshavarz, T. 2012. Laccase bio-grafting a versatile modification tool from green chemistry technologies. University of Westminster Faculty of Science and Technology Postgraduate Fair. University of Westminster, London, UK 26 Apr 2012

Hoyles, L. and McCartney, A.L. 2012. Genus IV. Mobiluncus. in: Whitman, W., Goodfellow, M., Kämpfer, P., Busse, H.J., Trujillo, M.E., Ludwig, W., Suzuki, K.I. and Parte, A. (ed.) Bergey’s Manual of Systematic Bacteriology. Volume Five The Actinobacteria, Part A and B Springer.

Foster, G., Wragg, P., Koylass, M.S., Whatmore, A.M. and Hoyles, L. 2012. Isolation of Actinomyces hyovaginalis from sheep and comparison with isolates obtained from pigs. Veterinary Microbiology. 157 (3-4), pp. 471-475. https://doi.org/10.1016/j.vetmic.2012.01.003

Hoyles, L., Honda, H., Logan, N.A., Halket, G., La Ragione, R.M. and McCartney, A.L. 2012. Recognition of greater diversity of Bacillus species and related bacteria in human faeces. Research in Microbiology. 163 (1), pp. 3-13. https://doi.org/10.1016/j.resmic.2011.10.004

Tsitsiou, E., Williams, A.E., Moschos, S.A., Patel, K., Rossios, C., Jiang, X., Adams, O.D., Macedo, P., Booton, R., Gibeon, D., Chung, K.F. and Lindsay, M.A. 2012. Transcriptome analysis shows activation of circulating CD8+ T cells in patients with severe asthma. Journal of Allergy and Clinical Immunology. 129 (1), pp. 95-103. https://doi.org/10.1016/j.jaci.2011.08.011

Terstyanszky, G., Kiss, T., Kukla, T., Lichtenberger, Z., Winter, S., Greenwell, P., McEldowney, S. and Heindl, H. 2012. Application repository and science gateway for running molecular docking and dynamics simulations. in: Gesing, S., Glatard, T., Kruger, J., Delgado Olabarriaga, S., Solomonides, T., Silverstein, J.C., Montagnat, J., Gaignard, A. and Krefting, D. (ed.) Healthgrid applications and technologies meet science gateways for life sciences IOS Press.

Peel, A.J., Baker, K.S., Crameri, G., Barr, J.A., Hayman, D.T.S., Wright, E., Broder, C.C., Fernández-Loras, A., Fooks, A.R., Wang, L.F., Cunningham, A.A. and Wood, J.L.N. 2012. Henipavirus neutralising antibodies in an isolated island population of African fruit bats. PLoS ONE. 7 (1) e30346. https://doi.org/10.1371/journal.pone.0030346

Opoku-Okrah, C., Smith, C.L., Gordge, M.P., Parry, M., Robertson, C.E., Abgenyega, T. and Nakua, E. 2012. Alpha thalassaemia and the severity of Plasmodium falciparum infection in microcytic children from the Ashanti region of Ghana. British Society for Haematology 52nd meeting. Glasgow 16-18 April 2012

Milton, N.G.N., Chilumuri, A., Rocha-Ferreira, E., Nercessian, A.N. and Ashioti, M. 2012. Kisspeptin prevention of Amyloid-β Peptide neurotoxicity in vitro. ACS chemical neuroscience. 3 (9), pp. 706-719. https://doi.org/10.1021/cn300045d

Milton, N.G.N. 2012. Kissorphin, a hexapeptide derivative of Kisspeptin, acts via Neuropeptide FF receptors to inhibit cyclic adenosine monophosphate release but has no Gonadotrophin-Releasing-Hormone releasing activity. Endocrine Abstracts. 28, p. OC2.3.

Milton, N.G.N. 2012. In vitro activities of Kissorphin, a novel hexapeptide KiSS-1 derivative, in neuronal cells. Journal of Amino Acids. 2012 691463. https://doi.org/10.1155/2012/691463

Harris, J.R. and Milton, N.G.N. 2012. Introduction and technical survey: protein aggregation and fibrillogenesis. Subcellular Biochemistry. 65, pp. 3-25. https://doi.org/10.1007/978-94-007-5416-4_1

Gyamfi, D., Everitt, H.E. and Patel, V. 2012. Chinese herbal products in the prevention and treatment of liver disease. in: Watson, R.R. and Preedy, V.R. (ed.) Bioactive food as dietary interventions for liver and gastrointestinal disease Academic Press. pp. 537-550

Evans, J., Wright, E., Fooks, A.R., Easton, A. and Banyard, A.C. 2012. Investigating antigenic epitopes on the lyssavirus glycoprotein. Society For General Microbiology Spring Meeting. Dublin 2012

Dalli, J., Montero-Melendez, T., McArthur, S. and Perretti, M. 2012. Annexin A1 N-terminal derived Peptide ac2-26 exerts chemokinetic effects on human neutrophils. Frontiers in Pharmacology. 3 28. https://doi.org/10.3389/fphar.2012.00028

Cucurull-Sanchez, L., Spink, K.G. and Moschos, S.A. 2012. Relevance of systems pharmacology in drug discovery. Drug Discovery Today. 17 (13-14), pp. 665-670. https://doi.org/10.1016/j.drudis.2012.01.015

Mackenzie, R.W.A., Elliott, B.T., Maxwell, N.S., Brickley, G. and Watt, P.W. 2012. The effect of hypoxia and work intensity on insulin resistance in type 2 diabetes. Journal of Clinical Endocrinology and Metabolism. 97 (1), pp. 155-162. https://doi.org/10.1210/jc.2011-1843

Dowejko, M.M., Smith, C.L., Getting, S.J., Le Tissier, P. and Murray, J.F. 2012. Expression of melanocortin 3 receptors (MC3) in the reproductive axes of both male and female mice. Society for Reproduction and Fertility. Edinburgh 9th - 11th July 2012

Suhy, D.A., Kao, S.C., Mao, T., Whiteley, L., Denise, H., Souberbielle, B., Burdick, A.D., Hayes, K., Wright, J.F., Lavender, H., Roelvink, P., Kolykhalov, A., Brady, K., Moschos, S.A., Hauck, B., Zelenaia, O., Zhou, S., Scribner, C., High, K.A., Renison, S.H. and Corbau, R. 2012. Safe, long-term hepatic expression of anti-HCV shRNA in a nonhuman primate model. Molecular Therapy. 20 (9), pp. 1737-1749. https://doi.org/10.1038/mt.2012.119

Xiao, F. and Gordge, M.P. 2011. Cell surface thiol isomerases may explain the platelet-selective action of S-nitrosoglutathione. Nitric Oxide: Biology and Chemistry. 25 (3), pp. 303-308. https://doi.org/10.1016/j.niox.2011.05.008

Thorasin, T., Hoyles, L. and McCartney, A.L. 2011. Investigations of the human faecal Coriobacteriaceae population. International Scientific Conference on Nutraceuticals and Functional Foods – FF2011. Kosice, Slovakia 25 Oct 2011

Wood, K.C., Batchelor, A.M., Bartus, K., Harris, K.L., Garthwaite, G., Vernon, J. and Garthwaite, J. 2011. Picomolar nitric oxide signals from central neurons recorded using ultrasensitive detector cells. Journal of Biological Chemistry. 286 (50), pp. 43172-43181. https://doi.org/10.1074/jbc.M111.289777

Hoyles, L., McCartney, A.L. and van Sinderen, D. 2011. Isolation of a Klebsiella bacterium–bacteriophage combination from human caecum effluent. SGM Autumn Conference. University of York, UK 05 Sep 2011

Gillies, R.M., Robinson, S.P., McPhail, L.D., Carter, N.D. and Murray, J.F. 2011. Immunohistochemical assessment of intrinsic and extrinsic markers of hypoxia in reproductive tissue: differential expression of HIF1α and HIF2α in rat oviduct and endometrium. Journal of Molecular Histology. 42 (4), pp. 341-354. https://doi.org/10.1007/s10735-011-9338-2

Laxton, C., Brady, K., Moschos, S.A., Turnpenny, P., Rawal, J., Pryde, D.C., Sidders, B., Corbau, R., Pickford, C. and Murray, E.J. 2011. Selection, optimization, and pharmacokinetic properties of a novel, potent antiviral locked nucleic acid-based antisense oligomer targeting hepatitis C virus internal ribosome entry site. Antimicrobial Agents and Chemotherapy. 55 (7), pp. 3105-3114. https://doi.org/10.1128/AAC.00222-11

Balazs, R., Vernon, J. and Hardy, J. 2011. Epigenetic mechanisms in Alzheimer's disease: progress but much to do. Neurobiology of Aging. 32 (7), pp. 1181-1187. https://doi.org/10.1016/j.neurobiolaging.2011.02.024

Wright, E., Mugaba, S., Grant, P., Parkes-Ratanshi, R., Van der Paal, L., Grosskurth, H. and Kaleebu, P. 2011. Coreceptor and cytokine concentrations may not explain differences in disease progression observed in HIV-1 clade A and D infected Ugandans. PLoS ONE. 6 (5) e19902. https://doi.org/10.1371/journal.pone.0019902

Hoyles, L., Neve, H., McCartney, A.L. and van Sinderen, D. 2011. Investigation of bacteriophage diversity associated with the human gastrointestinal microbiota. SGM Irish Division: Microbial Viruses: Genomics, Evolution and Applications in Ecology, Biotechnology and Medicine. University of Belfast, UK 19 Apr 2011

Brock, G.J., Moschos, S.A., Spivack, S.D. and Hurteau, G.J. 2011. The 3 prime paradigm of the miR-200 family and other microRNAs. Epigenetics. 6 (3), pp. 268-272. https://doi.org/10.4161/epi.6.3.14635

Inness, V.L., Khoo, C., Gross, K.L., Hoyles, L., Gibson, G.R. and McCartney, A.L. 2011. Use of static batch culture systems to investigate the fermentation effects of selected oligosaccharides and fibres by the canine faecal microbiota. International Journal of Probiotics and Prebiotics. 6 (1), pp. 57-64.

Markiv, A., Anani, B., Durvasula, R.V. and Kang, A.S. 2011. Module based antibody engineering: a novel synthetic REDantibody. Journal of Immunological Methods. 364 (1-2), pp. 40-49. https://doi.org/10.1016/j.jim.2010.10.009

Holloway, P.M., Smith, H.K., Renshaw, D., Flower, R.J., Getting, S.J. and Gavins, F.N.E. 2011. Targeting the melanocortin receptor system for anti-stroke therapy. Trends in Pharmacological Sciences. 32 (2), pp. 90-98. https://doi.org/10.1016/j.tips.2010.11.010

Heindl, H., Greenwell, P., Weingarten, N., Kiss, T., Terstyanszky, G. and Weinzierl, R.O.J. 2011. Cation-π interactions induce kinking of a molecular hinge in the RNA polymerase bridge-helix domain. Biochemical Society Transactions. 39 (1), pp. 31-35. https://doi.org/10.1042/BST0390031

Bramham, K., Hilton, R., Horsfield, C., McDonald, V., Camilleri, R. and Hunt, B.J. 2011. ADAMTS-13 deficiency: can it cause chronic renal failure? Nephrology, Dialysis, Transplantation. 26 (2), pp. 742-744. https://doi.org/10.1093/ndt/gfq644

Honda, H., Hoyles, L., Gibson, G.R. and Farmer, S. 2011. Impact of GanedenBC30 (Bacillus coagulans GBI-30, 6086) on population dynamics of the human gut microbiota in a continuous culture fermentation system. International Journal of Probiotics and Prebiotics. 6 (1), pp. 65-72.

Hoyles, L., Neve, H., McCartney, A.L. and van Sinderen, D. 2011. Investigation of bacteriophage diversity associated with the human gastrointestinal microbiota. SGM Irish Division: Microbial Viruses: Genomics, Evolution and Applications in Ecology, Biotechnology and Medicine. University of Belfast, UK 19 Apr 2011

Hoyles, L., McCartney, A.L. and van Sinderen, D. 2011. Isolation of a Klebsiella bacterium–bacteriophage combination from human caecum effluent. SGM Autumn Conference. University of York, UK 05 Sep 2011

Thorasin, T., Hoyles, L. and McCartney, A.L. 2011. Pilot study investigating the Coriobacteriaceae population of the human gastrointestinal microbiota. International Scientific Conference on Nutraceuticals and Functional Foods – FF2011. Kosice, Slovakia 25 Oct 2011

Inness, V.L., Khoo, C., Gross, K.L., Hoyles, L., Gibson, G.R. and McCartney, A.L. 2011. Use of static batch culture systems to investigate the fermentation effects of selected oligosaccharides and fibres by the canine faecal microbiota. International Journal of Probiotics and Prebiotics. 6, pp. 57-64.