Prof John Murphy

Prof John Murphy

2026

Expression and signaling patterns of CD180/MD-1 and CD150 in Chronic Lymphocytic Leukaemia (CLL) cells
Tamar Tsertsvadze, Kurtis Edwards, Sarah John-Olabode, Irina Datikashvili-David, Ani Bilanishvili, John Murphy, Emanuela V. Volpi, Peter M Lydyard and Nina Porakishvili 2026. Expression and signaling patterns of CD180/MD-1 and CD150 in Chronic Lymphocytic Leukaemia (CLL) cells. Leukemia Research. 162 108169. https://doi.org/10.1016/j.leukres.2026.108169

2026

The Effect of IL-4 on CD180 Expression and Signalling in Chronic Lymphocytic Leukaemia (CLL)
Ani Bilanishvili, Tamar Tsertsvadze, Kurtis Edwards, Sarah John-Olabode, Uzma Syed, Irina Datikashvili-David, Emanuela V. Volpi, John Murphy, Peter M. Lydyard and Nina Porakishvili 2026. The Effect of IL-4 on CD180 Expression and Signalling in Chronic Lymphocytic Leukaemia (CLL). Leukemia Research. 161 108166. https://doi.org/10.1016/j.leukres.2026.108166

2023

RNA Binding Proteins and Osteosarcoma
Oluigbo, N., Murphy, J.J. and Surendranath, K. 2023. RNA Binding Proteins and Osteosarcoma. J. Cancer Research and Cellular Therapeutics. 7 (2). https://doi.org/10.31579/2640-1053/146

2023

A deep learning workflow for quantification of Micronuclei in DNA damage studies in cultured cancer cell lines: a proof of principle investigation
Anand Panchbhai, Munuse Ceyda Ishanzadeh, Smarana Pankanti, Ahmed Sidali, Nadeeen Solaiman, Radhakrishnan Kanagaraj, John J. Murphy and Kalpana Surendranath 2023. A deep learning workflow for quantification of Micronuclei in DNA damage studies in cultured cancer cell lines: a proof of principle investigation. Computer Methods and Programs in Biomedicine. 232 107447. https://doi.org/10.1016/j.cmpb.2023.107447

2021

AU-Rich Element RNA Binding Proteins: At the Crossroads of Post-Transcriptional Regulation and Genome Integrity.
Sidali, A., Teotia, Varsha, Solaiman, Nadeen Shaikh, Bashir, Nahida, Kanagaraj, Radhakrishnan, Murphy, J. and Surendranath, K. 2021. AU-Rich Element RNA Binding Proteins: At the Crossroads of Post-Transcriptional Regulation and Genome Integrity. International Journal of Molecular Sciences. 23 (1) 96. https://doi.org/10.3390/ijms23010096

2019

Prostate Cancer: The role of inflammation and chemokines
Rani, A., Dasgupta, P. and Murphy, J.J. 2019. Prostate Cancer: The role of inflammation and chemokines. American Journal of Pathology. 189 (11), pp. 2119-2137. https://doi.org/10.1016/j.ajpath.2019.07.007

2019

Endocrine Resistance in Hormone Receptor Positive Breast Cancer–From Mechanism to Therapy
Rani, A., Stebbing, J., Giamas, G. and Murphy, J.J. 2019. Endocrine Resistance in Hormone Receptor Positive Breast Cancer–From Mechanism to Therapy. Frontiers in Endocrinology. 10 245. https://doi.org/10.3389/fendo.2019.00245

2014

Post-Transcriptional Regulation of BCL2 mRNA by the RNA-Binding Protein ZFP36L1 in Malignant B Cells
Zekavati, A., Nasir, A., Alcaraz, A., Aldrovandi, M., Marsh, P., Norton, J.D. and Murphy, J.J. 2014. Post-Transcriptional Regulation of BCL2 mRNA by the RNA-Binding Protein ZFP36L1 in Malignant B Cells. PLoS ONE. 9 (7) e102625. https://doi.org/10.1371/journal.pone.0102625

2012

ZFP36L1 negatively regulates plasmacytoid differentiation of BCL1 cells by targeting BLIMP1 mRNA
Nasir, A., Norton, J.D., Baou, M., Zekavati, A., Bijlmakers, M.J., Thompson, S. and Murphy, J.J. 2012. ZFP36L1 negatively regulates plasmacytoid differentiation of BCL1 cells by targeting BLIMP1 mRNA. PLoS ONE. 7 (12) e52187. https://doi.org/10.1371/journal.pone.0052187

2025

Advancing Research-Integrated Education: The Gene Editors Network of Excellence for Multidisciplinary Student Innovations and Global Impact
Surendranath, K., Chaurasia, H., Akhtar, M.M., Akhtar, M.M., Murphy, J.J., Dinmukhamedova, A. and Tleumbetova, N.N. 2025. Advancing Research-Integrated Education: The Gene Editors Network of Excellence for Multidisciplinary Student Innovations and Global Impact. British Educational Research Association Conference 2025. University of Sussex 09 - 11 Sep 2025 Wiley.

2009

Post-transcriptional regulator protein ZFP36L1 targeting of Bcl-2 mRNA
Zekavati, A., Marsh, P. and Murphy, J.J. 2009. Post-transcriptional regulator protein ZFP36L1 targeting of Bcl-2 mRNA. 2nd European Congress of Immunology. Berlin, Germany 13 – 16 September 2009

2009

Evidence for involvement of ZFP36L1 protein downregulation in differentiation of the murine BCL1 leukaemia cell line
Nasir, A., Roberts, H., Thompson, S. and Murphy, J.J. 2009. Evidence for involvement of ZFP36L1 protein downregulation in differentiation of the murine BCL1 leukaemia cell line. 2nd European Congress of Immunology. Berlin, Germany 13 – 16 September 2009

2008

Evidence for involvement of ZFP36L1 protein downregulation in differentiation of the murine BCL1 leukaemia cell line
Nasir, A., Roberts, H., Thompson, S. and Murphy, J.J. 2008. Evidence for involvement of ZFP36L1 protein downregulation in differentiation of the murine BCL1 leukaemia cell line. BSI Immunology Congress. Glasgow 17-21 November 2008

2024

DNA Replication Stress and the Human Genome: Hurdles, Hijacks and Cell Health
Teotia, V., Pantuczek, J., Kalladi, W.B.V., Murphy, J.J. and Surendranath, K. 2024. DNA Replication Stress and the Human Genome: Hurdles, Hijacks and Cell Health. in: Mary C. Maj and Felicia Ikolo (ed.) Cell and Molecular Biology Annual Volume 2025 IntechOpen.

2024

Progress and Prospects in CRISPR Genome Engineering Nucleases
Surendranath, K., Akram, K., Radhakrishnan, K., Savash Ishanzadeh, M.C., Khan, S., Pantuzcek, J., Karri, M., Guha, S., Rangan, S.L., Kour, E., Amalanathan, K.R. and Murphy, J.J. 2024. Progress and Prospects in CRISPR Genome Engineering Nucleases. in: Parthasarathy, K. and Manikkam, R. (ed.) Translational Research in Biomedical Sciences: Recent Progress and Future Prospects Springer, Singapore Springer Nature. pp. 44-79

2008

Mode of action of Rituximab in chronic lymphocytic leukaemia: activation of Tis11b, an inducer of mRNA instability and induction of apoptosis
Baou, M., Jewell, A.P., Yong, K.L. and Murphy, J.J. 2008. Mode of action of Rituximab in chronic lymphocytic leukaemia: activation of Tis11b, an inducer of mRNA instability and induction of apoptosis. in: Moreau, I.B. (ed.) Chronic lymphocytic leukemia: new research Nova Science Publishers. pp. 141-155

2015

Evidence for targeting of CD38 mRNA by the post-transcriptional regulator protein ZFP36L1
Murphy, J.J. 2015. Evidence for targeting of CD38 mRNA by the post-transcriptional regulator protein ZFP36L1. 4th European Congress of Immunology. Vienna 08 Sep 2015

2015

The Notch target Hes1, is a STAT5 target gene with implications in cancer
Rani, A., Greenlaw, R., Galustian, C. and Murphy, J.J. 2015. The Notch target Hes1, is a STAT5 target gene with implications in cancer. 2015 Meeting of the ICIS in Bamberg, Germany, October 11th -14th. Bamberg, Germany Oct 2015 https://doi.org/10.1016/j.cyto.2015.08.214

2016

STAT5 in Cancer and Immunity
Murphy, J.J. and Rani, A. 2016. STAT5 in Cancer and Immunity. Journal of Interferon & Cytokine Research. 36 (4), pp. 226-237. https://doi.org/10.1089/jir.2015.0054

2011

AU-rich RNA binding proteins in hematopoiesis and leukemogenesis
Baou, M., Norton, J.D. and Murphy, J.J. 2011. AU-rich RNA binding proteins in hematopoiesis and leukemogenesis. Blood. 118 (22), pp. 5732-5740. https://doi.org/10.1182/blood-2011-07-347237

2009

TIS11 family proteins and their roles in post-transcriptional gene regulation
Baou, M., Jewell, A.P. and Murphy, J.J. 2009. TIS11 family proteins and their roles in post-transcriptional gene regulation. Journal of Biomedicine and Biotechnology. 634520. https://doi.org/10.1155/2009/634520

2009

Involvement of Tis11b, an AU-rich binding protein, in induction of apoptosis by rituximab in B cell chronic lymphocytic leukemia cells
Baou, M., Jewell, A.P., Muthurania, A., Wickremasinghe, R.G., Yong, K.L., Carr, R., Marsh, P. and Murphy, J.J. 2009. Involvement of Tis11b, an AU-rich binding protein, in induction of apoptosis by rituximab in B cell chronic lymphocytic leukemia cells. Leukemia. 23 (5), pp. 986-989. https://doi.org/10.1038/leu.2008.340


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