The Reproducibility of 4-km Time Trial (TT) Performance Following Individualised Sodium Bicarbonate Supplementation: a Randomised Controlled Trial in Trained Cyclists

Gough, L., Deb, S., Sparks, S.A. and McNaughton, L. 2017. The Reproducibility of 4-km Time Trial (TT) Performance Following Individualised Sodium Bicarbonate Supplementation: a Randomised Controlled Trial in Trained Cyclists. Sports Medicine - open. 3 34. https://doi.org/10.1186/s40798-017-0101-4

TitleThe Reproducibility of 4-km Time Trial (TT) Performance Following Individualised Sodium Bicarbonate Supplementation: a Randomised Controlled Trial in Trained Cyclists
TypeJournal article
AuthorsGough, L.
Deb, S.
Sparks, S.A.
McNaughton, L.
Abstract

Background: Individual time to peak blood bicarbonate (HCO3(-)) has demonstrated good to excellent reproducibility following ingestion of both 0.2 g kg(-1) body mass (BM) and 0.3 g kg(-1) BM sodium bicarbonate (NaHCO3), but the consistency of the time trial (TT) performance response using such an individualised NaHCO3 ingestion strategy remains unknown. This study therefore evaluated the reproducibility of 4-km TT performance following NaHCO3 ingestion individualised to time to peak blood bicarbonate. Methods: Eleven trained male cyclists completed five randomised treatments with prior ingestion of 0.2 g kg(-1) (SBC2) or 0.3 g kg(-1) BM (SBC3) NaHCO3, on two separate occasions each, or a control trial entailing no supplementation. Participants completed a 4-km cycling TT on a Velotron ergometer where time to complete, power and speed were measured, whilst acid-base blood parameters were also recorded (pH and blood bicarbonate concentration HCO3(-)) and lactate [La(-)]. Results: Alkalosis was achieved prior to exercise in both SBC2 and SBC3, as pH and HCO3(-) were greater compared to baseline (p < 0.001), with no differences between treatments (p > 0.05). The reproducibility of the mean absolute change from baseline to peak in HCO3(-) was good in SBC2 (r = 0.68) and excellent in SBC3 (r = 0.78). The performance responses following both SBC2 and SBC3 displayed excellent reproducibility (r range = 0.97 to 0.99). Conclusions: Results demonstrate excellent reproducibility of exercise performance following individualised NaHCO3 ingestion, which is due to the high reproducibility of blood acid-base variables with repeat administration of NaHCO3. Using a time to peak HCO3(-) strategy seems to cause no dose-dependent effects on performance for exercise of this duration and intensity; therefore, athletes may consider smaller doses of NaHCO3 to mitigate gastrointestinal (GI) discomfort.

KeywordsBuffering, Alkalosis, Performance, Acid-base balance, Ergogenic aids, Reliability
Article number34
JournalSports Medicine - open
Journal citation3
ISSN2199-1170
Year2017
PublisherSpringer
Digital Object Identifier (DOI)https://doi.org/10.1186/s40798-017-0101-4
Publication dates
Published online21 Sep 2017
LicenseCC BY 4.0

Related outputs

Formulated Palmitoylethanolamide Supplementation Improves Parameters of Cognitive Function and BDNF Levels in Young, Healthy Adults: A Randomised Cross-Over Trial
Kim, N., Parolin, B., Renshaw, D., Deb, S. and Zariwala, Mohammed Gulrez 2024. Formulated Palmitoylethanolamide Supplementation Improves Parameters of Cognitive Function and BDNF Levels in Young, Healthy Adults: A Randomised Cross-Over Trial. Nutrients. 16 (4), p. 489. https://doi.org/10.3390/nu16040489

Greater male variability in daily energy expenditure develops through puberty
Halsey, L., Careau, V., Ainslie, Philip N., Alemán-Mateo, Heliodoro, Andersen, Lene F., Anderson, Liam J., Arab, Leonore, Baddou, Issad, Bandini, Linda, Bedu-Addo, Kweku, Blaak, E., Blanc, Stephane, Bonomi, Alberto G., Bouten, Carlijn V. C., Bovet, Pascal, Brage, Soren, Buchowski, Maciej S., Butte, Nancy, Camps, Stephan G., Casper, Regian, Close, Graeme L., Colbert, Lisa H., Cooper, Jamie A., Cooper, Richard, Dabare, Prasangi, Das, Sai Krupa, Davies, Peter S. W., Deb, Sanjoy, Nyström, Christine Delisle, Dietz, William, Dugas, Lara R., Eaton, Simon, Ekelund, Ulf, Hamdouchi, Asmaa El, Entringer, Sonja, Forrester, Terrence, Fudge, Barry W., Gillingham, Melanie, Goris, Annelies H., Gurven, Michael, Haisma, Hinke, Hambly, Catherine, Hoffman, Daniel, Hoos, Marije B., Hu, Sumei, Joonas, Noorjehan, Joosen, Annemiek, Katzmarzyk, Peter, Kempen, Kitty P., Kimura, Misaka, Kraus, William E., Kriengsinyos, Wantanee, Kuriyan, Rebecca, Kushner, Robert F., Lambert, Estelle V., Lanerolle, Pulani, Larsson, Christel L., Lessan, Nader, Löf, Marie, Martin, Corby, Matsiko, Eric, Meijer, Gerwin A., Morehen, James C., Morton, James P., Must, Aviva, Neuheuser, Marian, Nicklas, Theresa A., Ojiambo, Robert M., Pietilainen, Kirsi H., Pitsiladis, Yannis P., Plange-Rhule, Jacob, Plasqui, Guy, Prentice, Ross L., Rabinovich, Roberto, Racette, Susan B., Raichen, David A., Ravussin, Eric, Redman, Leanne, Reilly, John J., Reynolds, Rebecca, Roberts, Susan, Rood, Jennifer C., Samaranayake, Dulani, Sardinha, Luís B., Scuitt, Albertine J., Silva, Analiza M., Sinha, Srishti, Sjödin, Anders M., Stice, Eric, Stunkard, Albert, Urlacher, Samuel S., Valencia, Mauro Eduardo, Valenti, Giulio, van Etten, Ludo M., Van Mil, Edgar A., Verbunt, Jeanine A., Wells, Jonathan C. K., Wilson, George, Wood, Brian, Yoshida, Tsukasa, Zhang, Xueying, Murphy-Alford, Alexia, Loechl, Cornelia, Luke, Amy, Pontzer, Herman, Rood, Jennifer, Sagayama, Hiroyuki, Westerterp, Klaas R., Wong, William W., Yamada, Yosuke and Speakman, J. 2023. Greater male variability in daily energy expenditure develops through puberty. Biology Letters. 19 (9) 20230152. https://doi.org/10.1098/rsbl.2023.0152

An exploration into the impact that shift work has on the nutritional behaviours of UK police officers
Allen, K., Safi, A. and Deb, S. 2023. An exploration into the impact that shift work has on the nutritional behaviours of UK police officers. British Journal of Nutrition. 130 (2), pp. 284-293. https://doi.org/10.1017/s0007114522002999

Editorial: Survival in Extreme Environments - Adaptation or Decompensation? Volume II
Tveita, Torkjel, Eftedal, Ingrid and Deb, Sanjoy 2022. Editorial: Survival in Extreme Environments - Adaptation or Decompensation? Volume II. Frontiers in Physiology. 13 1106903. https://doi.org/10.3389/fphys.2022.1106903

Supporting doctors' nutrition in the workplace: findings from a qualitative study
Sum, K., Cheshire, A., Ridge, D. and Deb, S. 2022. Supporting doctors' nutrition in the workplace: findings from a qualitative study. The Nutrition Society's Summer Conference 2022. Sheffield Hallam University 12 - 15 Jul 2022 Cambridge University Press. https://doi.org/10.1017/S002966512200194X

Behavior Change Techniques in Digital Health Interventions for Midlife Women: Systematic Review
Hana Sediva, Tina Cartwright, Claire Robertson and Deb, S. 2022. Behavior Change Techniques in Digital Health Interventions for Midlife Women: Systematic Review. JMIR mHealth and uHealth. 10 (11) e37234. https://doi.org/10.2196/37234

The impact of health care strikes on patient mortality: A systematic review and meta‐analysis of observational studies
Essex, R., Weldon, Sharon Marie, Thompson, Trevor, Kalocsányiová, Erika, McCrone, Paul and Deb, Sanjoy 2022. The impact of health care strikes on patient mortality: A systematic review and meta‐analysis of observational studies. Health Services Research. 57 (6), pp. 1218-1234. https://doi.org/10.1111/1475-6773.14022

Editorial: Survival in Extreme Environments - Adaptation or Decompensation? Volume I
Tveita, Torkjel, Eftedal, Ingrid and Deb, Sanjoy 2022. Editorial: Survival in Extreme Environments - Adaptation or Decompensation? Volume I. Frontiers in Physiology. 13, p. 836210. https://doi.org/10.3389/fphys.2022.836210

A Comparison of Physical Activity and Sedentary Lifestyle of University Employees through ActiGraph and IPAQ-LF
Safi, A., Cole, M., Kelly, A., Deb, S. and Walker, N. 2022. A Comparison of Physical Activity and Sedentary Lifestyle of University Employees through ActiGraph and IPAQ-LF. Physical Activity and Health. 6 (1), pp. 5-15. https://doi.org/10.5334/paah.163

Impact of healthcare strikes on patient mortality: a protocol for a systematic review and meta-analysis of observational studies
Essex, R., Weldon, S.M., Thompson, T., Kalocsanyiova, E., McCrone, E. and Deb, S. 2021. Impact of healthcare strikes on patient mortality: a protocol for a systematic review and meta-analysis of observational studies . BMJ Open. 11 e050826. https://doi.org/10.1136/bmjopen-2021-050826

Using Salivary Biomarkers for Stress Assessment in Offshore Saturation Diving: A Pilot Study
Monnoyer, Roxane, Lautridou, Jacky, Deb, Sanjoy, Hjelde, Astrid and Eftedal, Ingrid 2021. Using Salivary Biomarkers for Stress Assessment in Offshore Saturation Diving: A Pilot Study. Frontiers in Physiology. 12, p. 791525 791525. https://doi.org/10.3389/fphys.2021.791525

Functional Profiling Reveals Altered Metabolic Activity in Divers’ Oral Microbiota During Commercial Heliox Saturation Diving
Monnoyer, R, Eftedal, I, Hjelde, A, Deb, S., Haugum, K and Lautridou, J 2021. Functional Profiling Reveals Altered Metabolic Activity in Divers’ Oral Microbiota During Commercial Heliox Saturation Diving. Frontiers in Physiology. 12 702634. https://doi.org/10.3389/fphys.2021.702634

Comparative Assessment of the Acute Effects of Whey, Rice and Potato Protein Isolate Intake on Markers of Glycaemic Regulation and Appetite in Healthy Males Using a Randomised Study Design
Tiekou Lorinczova, Helena, Deb, Sanjoy, Begum, G., Renshaw, Derek and Zariwala, Mohammed Gulrez 2021. Comparative Assessment of the Acute Effects of Whey, Rice and Potato Protein Isolate Intake on Markers of Glycaemic Regulation and Appetite in Healthy Males Using a Randomised Study Design. Nutrients. 13 (7). https://doi.org/nu13072157

The Assessment of Daily Energy Expenditure of Commercial Saturation Divers Using Doubly Labelled Water
Deb, S., Dolan, Eimear, Hambly, Catherine, Speakman, John R., Eftedal, Olav, Zariwala, Mohammed Gulrez and Eftedal, Ingrid 2021. The Assessment of Daily Energy Expenditure of Commercial Saturation Divers Using Doubly Labelled Water. Frontiers in Physiology. 12 687605. https://doi.org/10.3389/fphys.2021.687605

The effect of astaxanthin supplementation on performance and fat oxidation during a 40 km cycling time trial
Brown, D.R., Warner, A.R., Deb, S., Gough, L.A., Sparks, S.A. and McNaughton, L.R. 2021. The effect of astaxanthin supplementation on performance and fat oxidation during a 40 km cycling time trial. Journal of Science and Medicine in Sport. 24 (1), pp. 92-97. https://doi.org/10.1016/j.jsams.2020.06.017

High dose Nitrate ingestion does not improve 40 km cycling time trial performance in trained cyclists
Mosher, S., Gough, L., Deb, S., Saunders, B., McNaughton, L., Brown, D. and Sparks, S.A. 2020. High dose Nitrate ingestion does not improve 40 km cycling time trial performance in trained cyclists. Research in Sports Medicine: an International Journal. 28 (1), pp. 138-146. https://doi.org/10.1080/15438627.2019.1586707

The effects of sodium bicarbonate ingestion on cycling performance and acid base balance recovery in acute normobaric hypoxia
Gough, L., Brown, D., Deb, S., Sparks, S.A. and McNaughton, L. 2019. The effects of sodium bicarbonate ingestion on cycling performance and acid base balance recovery in acute normobaric hypoxia. Journal of Sports Sciences. 37 (13), pp. 1464-1471. https://doi.org/10.1080/02640414.2019.1568173

A novel ingestion strategy for sodium bicarbonate supplementation in a delayed-release form: a randomised crossover study in trained males
Hilton, N., Leach, N., Sparks, S.A., Gough, L., Deb, S., Craig, M. and McNaughton, L. 2019. A novel ingestion strategy for sodium bicarbonate supplementation in a delayed-release form: a randomised crossover study in trained males. Sports Medicine - open. 5 (4). https://doi.org/10.1186/s40798-019-0177-0

Buffering agents: Sodium Bicarbonate, Sodium Citrate, Sodium Phosphate
McNaughton, L., Brewer, C., Deb, S., Hilton, N., Gough, L. and Sparks, S.A. 2019. Buffering agents: Sodium Bicarbonate, Sodium Citrate, Sodium Phosphate. in: Hoffman, J. (ed.) Dietary Supplementation in Sport and Exercise: Evidence, Safety, and Ergogenic Benefits Routledge. pp. 191-205

Quantifying the effects of acute hypoxic exposure on exercise performance and capacity: A systematic review and meta-regression
Deb, S., Brown, D., Gough, L., Mclellan, C.P., Swinton, P., Sparks, S.A. and McNaughton, L. 2018. Quantifying the effects of acute hypoxic exposure on exercise performance and capacity: A systematic review and meta-regression. European Journal of Sport Science. 18 (2), pp. 243-256. https://doi.org/10.1080/17461391.2017.1410233

Sodium bicarbonate supplementation improves severe-intensity intermittent exercise under moderate acute hypoxic conditions
Deb, S., Gough, L., Sparks, S.A. and McNaughton, L. 2018. Sodium bicarbonate supplementation improves severe-intensity intermittent exercise under moderate acute hypoxic conditions. European Journal of Applied Physiology. 118 (3), pp. 607-615. https://doi.org/10.1007/s00421-018-3801-7

The influence of alkalosis on repeated high-intensity exercise performance and acid–base balance recovery in acute moderate hypoxic conditions
Gough, L., Brown, D., Deb, S., Sparks, S.A. and McNaughton, L. 2018. The influence of alkalosis on repeated high-intensity exercise performance and acid–base balance recovery in acute moderate hypoxic conditions. European Journal of Applied Physiology. 118 (12), p. 2489–2498. https://doi.org/10.1007/s00421-018-3975-z

Sodium bicarbonate improves 4 km time trial cycling performance when individualised to time to peak blood bicarbonate in trained male cyclists
Gough, L., Deb, S., Sparks, S.A. and McNaughton, L. 2018. Sodium bicarbonate improves 4 km time trial cycling performance when individualised to time to peak blood bicarbonate in trained male cyclists. Journal of Sports Sciences. 36 (15), pp. 1705-1712. https://doi.org/10.1080/02640414.2017.1410875

The Reproducibility of Blood Acid Base Responses in Male Collegiate Athletes Following Individualised Doses of Sodium Bicarbonate: A Randomised Controlled Crossover Study
Gough, L., Deb, S., Sparks, S.A. and McNaughton, L. 2017. The Reproducibility of Blood Acid Base Responses in Male Collegiate Athletes Following Individualised Doses of Sodium Bicarbonate: A Randomised Controlled Crossover Study. Sports Medicine. 47 (10), p. 2117–2127. https://doi.org/10.1007/s40279-017-0699-x

Physiological responses to prolonged saturation diving: a field based pilot study
Deb, S., Burgess, K., Swinton, P. and Dolan, E. 2017. Physiological responses to prolonged saturation diving: a field based pilot study. Undersea and Hyperbaric Medicine: journal of the Undersea and Hyperbaric Medical Society. 44 (6), pp. 581-587. https://doi.org/10.22462/11.12.2017.9

Astaxanthin in Exercise Metabolism, Performance and Recovery: A Review
Brown, D., Gough, L., Deb, S., Sparks, S.A. and McNaughton, L. 2017. Astaxanthin in Exercise Metabolism, Performance and Recovery: A Review. Frontiers in Nutrition. 4 76. https://doi.org/10.3389/fnut.2017.00076

Determinants of curvature constant (W’) of the power duration relationship under normoxia and hypoxia: the effect of pre-exercise alkalosis
Deb, S., Gough, L., Sparks, S.A. and McNaughton, L. 2017. Determinants of curvature constant (W’) of the power duration relationship under normoxia and hypoxia: the effect of pre-exercise alkalosis. European Journal of Applied Physiology. 117 (5), pp. 901-912. https://doi.org/10.1007/s00421-017-3574-4

Nutritional considerations during prolonged exposure to a confined, hyperbaric, hyperoxic environment: Recommendations for saturation divers
Deb, S., Swinton, P. and Dolan, E. 2016. Nutritional considerations during prolonged exposure to a confined, hyperbaric, hyperoxic environment: Recommendations for saturation divers. Extreme Physiology and Medicine. 7 (5), p. 1 1. https://doi.org/10.1186/s13728-015-0042-9

Brief communication: Self-reported health and activity habits and attitudes in saturation divers
Dolan, E., Deb, S., Stephan, G. and Swinton, P. 2016. Brief communication: Self-reported health and activity habits and attitudes in saturation divers. Undersea and Hyperbaric Medicine: journal of the Undersea and Hyperbaric Medical Society. 43 (2), pp. 93-101.

Recent Developments in the Use of Sodium Bicarbonate as an Ergogenic Aid
McNaughton, L., Bentley, D., Deb, S., Gough, L. and Sparks, S.A. 2016. Recent Developments in the Use of Sodium Bicarbonate as an Ergogenic Aid. Current Sports Medicine Reports. 15 (4), pp. 233-244. https://doi.org/10.1249/JSR.0000000000000283

Permalink - https://westminsterresearch.westminster.ac.uk/item/q97wv/the-reproducibility-of-4-km-time-trial-tt-performance-following-individualised-sodium-bicarbonate-supplementation-a-randomised-controlled-trial-in-trained-cyclists


Restricted files

Accepted author manuscript

Under embargo indefinitely

Share this

Usage statistics

163 total views
36 total downloads
These values cover views and downloads from WestminsterResearch and are for the period from September 2nd 2018, when this repository was created.