Quantifying the effects of acute hypoxic exposure on exercise performance and capacity: A systematic review and meta-regression

Deb, S., Brown, D., Gough, L., Mclellan, C.P., Swinton, P., Sparks, S.A. and McNaughton, L. 2018. Quantifying the effects of acute hypoxic exposure on exercise performance and capacity: A systematic review and meta-regression. European Journal of Sport Science. 18 (2), pp. 243-256. doi:10.1080/17461391.2017.1410233

TitleQuantifying the effects of acute hypoxic exposure on exercise performance and capacity: A systematic review and meta-regression
TypeJournal article
AuthorsDeb, S., Brown, D., Gough, L., Mclellan, C.P., Swinton, P., Sparks, S.A. and McNaughton, L.
Abstract

Objective: To quantify the effects of acute hypoxic exposure on exercise capacity and performance, which includes continuous and intermittent forms of exercise. Design: A systematic review was conducted with a three-level mixed effects meta-regression. The ratio of means method was used to evaluate main effects and moderators providing practical interpretations with percentage change. Data Sources: A systemic search was performed using 3 databases (Google scholar, PubMed and SPORTDiscus). Eligibility criteria for selecting studies: Inclusion was restricted to investigations that assessed exercise performance (time trials, sprint, and intermittent exercise tests) and capacity (time to exhaustion test (TTE)) with acute hypoxic (< 24 hrs) exposure and a normoxic comparator. Results: Eighty-two outcomes from 53 studies (N = 798) were included in this review. The results show an overall reduction in exercise performance/capacity -17.8 ± 3.9% (95% CI -22.8% to -11.0%), which was significantly moderated by -6.5 ± 0.9% per 1000 m altitude elevation (95% CI -8.2% to -4.8%) and oxygen saturation (-2.0 ± 0.4% 95% CI -2.9% to -1.2%). Time trial (-16.2 ± 4.3%; 95% CI -22.9% to -9%) and TTE (-44.5 ± 6.9%; 95% CI -51.3% to -36.7%) elicited a negative effect, whilst indicating a quadratic relationship between hypoxic magnitude and both TTE and TT performance. Furthermore, exercise < 2-min exhibited no ergolytic effect from acute hypoxia. Summary/ Conclusion: This review highlights the ergolytic effect of acute hypoxic exposure; which is curvilinear for TTE and TT performance with increasing hypoxic levels, but short-duration intermittent and sprint exercise seem to be unaffected.

KeywordsAltitude, intermittent hypoxic training, extreme environments, environmental physiology
JournalEuropean Journal of Sport Science
Journal citation18 (2), pp. 243-256
ISSN1746-1391
Year2018
PublisherTaylor & Francis
Accepted author manuscriptDeb et al. Hypoixa meta-regression manuscirpt EJSS Accpeted.pdf
Digital Object Identifier (DOI)doi:10.1080/17461391.2017.1410233
Publication dates
Published online08 Dec 2017
Published in print2018

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