Biomedical Sciences

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The efficacy of current rabies vaccines and novel Nanobody®-based antivirals against highly pathogenic phylogroup -1 and -2 members of the Lyssavirus genus

Conference paper

Wright, E., Hultberg, A., Rosseels, V., Vaughan, A., Saunders, M., Koenders, M., Verrips, T., Fooks, A.R., Vanlandschoot, P., Weiss, R.A., van Gucht, S. and de Haard, H.J. 2010. The efficacy of current rabies vaccines and novel Nanobody®-based antivirals against highly pathogenic phylogroup -1 and -2 members of the Lyssavirus genus. Rabies In The Americas XXI. Guadalajara, Mexico 2010

Mechanisms of Urocortin family peptide mediated chondroprotection

Conference poster

White, O.B., Intekhab Alam, N.Y., Chowdrey, H.S., Knight, R.A. and Locke, I.C. 2010. Mechanisms of Urocortin family peptide mediated chondroprotection. OARSI 2010 World Congress on Osteoarthritis. Brussels, Belgium September 23-26, 2010 https://doi.org/10.1016/S1063-4584(10)60288-9

Downstream gene activation of the receptor ALX by the agonist Annexin A1

Journal article

Renshaw, D., Montero-Melendez, T., Dalli, J., Kamal, A., Brancaleone, V., D'Acquisto, F., Cirino, G. and Perretti, M. 2010. Downstream gene activation of the receptor ALX by the agonist Annexin A1. PLoS ONE. 5 (9) e12771. https://doi.org/10.1371/journal.pone.0012771

Circulating melanin concentrating hormone (MCH) concentrations in the menstrual cycle

Conference paper

Naufahu, J., Cunliffe, A. and Murray, J.F. 2010. Circulating melanin concentrating hormone (MCH) concentrations in the menstrual cycle. Society for Reproduction and Fertility. Sutton Bonnington 11th - 13th July 2010

Expression of endogenous and exogenous hypoxic markers in sheep preovulatory antral follicles

Conference paper

Murray, J.F., Gillies, R.M., Carter, N.D. and Robinson, S.P. 2010. Expression of endogenous and exogenous hypoxic markers in sheep preovulatory antral follicles. Society for Reproduction and Fertility. Sutton Bonnington 11th - 13th July 2010

The role of miRNA in diagnostics

Article

Moschos, S.A. 2010. The role of miRNA in diagnostics. International Drug Discovery. Online only.

Annexin A1: a central player in the anti-inflammatory and neuroprotective role of microglia

Article

McArthur, S., Cristante, E., Paterno, M., Christian, H.C., Roncaroli, F., Gillies, G.E. and Solito, E. 2010. Annexin A1: a central player in the anti-inflammatory and neuroprotective role of microglia. Journal of Immunology. 185 (10), pp. 6317-6328. https://doi.org/10.4049/jimmunol.1001095

Acute hypoxia improves insulin sensitivity (SI2*) and β cell function in individuals with Type 2 Diabetes

Conference item

Mackenzie, R.W.A., Elliott, B.T., Brickley, G. and Watt, P.W. 2010. Acute hypoxia improves insulin sensitivity (SI2*) and β cell function in individuals with Type 2 Diabetes. The Physiological Society. University of Manchester

Molecular docking simulations on a combined desktop and service grid infrastructure

Book chapter

Kiss, T., Szmetanko, G., Terstyanszky, G., Greenwell, P. and Heindl, H. 2010. Molecular docking simulations on a combined desktop and service grid infrastructure. in: Proceedings: Third AlmereGrid Desktop Experience workshop: desktop grid applications for eScience and eBusiness, 30 March 2010, Almere, The Netherlands EnterTheGrid. pp. 23-27

Parameter sweep workflows for modelling carbohydrate recognition

Article

Kiss, T., Greenwell, P., Heindl, H., Terstyanszky, G. and Weingarten, N. 2010. Parameter sweep workflows for modelling carbohydrate recognition. Journal of Grid Computing. 8 (4), pp. 587-601. https://doi.org/10.1007/s10723-010-9166-8

ProSim: development of a user-friendly molecular modelling package

Book chapter

Heindl, H., Kiss, T., Terstyanszky, G., Weingarten, N., Afrough, B. and Greenwell, P. 2010. ProSim: development of a user-friendly molecular modelling package. in: Hicks, M.G. and Kettner, C. (ed.) Proceedings of the International Beilstein Symposium on Glyco-Bioinformatics: Bits ‘n’ Bytes of Sugars, October 4th – 8th, 2009, Potsdam, Germany Beilstein-Institut zur Fo¨rderung der Chemischen Wissenschaften. pp. 61-85

Cholesterol in Alzheimer's disease and other amyloidogenic disorders

Article

Harris, J.R. and Milton, N.G.N. 2010. Cholesterol in Alzheimer's disease and other amyloidogenic disorders. Subcellular Biochemistry. 51, pp. 47-75. https://doi.org/10.1007/978-90-481-8622-8_2

Apoptosis in alcoholic liver disease

Book chapter

Gyamfi, D., Everitt, H.E. and Patel, V. 2010. Apoptosis in alcoholic liver disease. in: Preedy, V.R. (ed.) Apoptosis: modern insights into disease from molecules to man Science Publishers. pp. 211-233

Flow cytometric identification of cell types in digested mouse lung

Conference poster

Graves, H., Taylor, B., Mechiche, H. and Moschos, S.A. 2010. Flow cytometric identification of cell types in digested mouse lung. 9th Annual Symposium on Biopharmaceuticals - San Diego Bio-Pharma Conference. Hilton San Diego/Del Mar, Del Mar 05 Jun 2010

The effect of acute alcohol exposure on hepatic oxidative stress and function: prevention by micronutrients

PhD thesis

Everitt, H.E. 2010. The effect of acute alcohol exposure on hepatic oxidative stress and function: prevention by micronutrients. PhD thesis University of Westminster School of Life Sciences https://doi.org/10.34737/905vx

Development of a novel serological assay for the detection of rabies virus neutralising antibodies using lentiviral pseudotypes

Conference paper

Armson, B.L., Wright, E., McElhinney, L.M., Banyard, A.C., Goddard, T., Healy, D.M., Voller, K., Weiss, R.A. and Fooks, A.R. 2010. Development of a novel serological assay for the detection of rabies virus neutralising antibodies using lentiviral pseudotypes. 4th Annual Meeting EPIZONE. Saint Malo, France 2010

Testicular LH-stimulated testosterone production is inhibited by activation of melanocortin 3 receptors (MC3)

Conference paper

Akindele, K., Horanin, M.M., Getting, S.J., Smith, C.L. and Murray, J.F. 2010. Testicular LH-stimulated testosterone production is inhibited by activation of melanocortin 3 receptors (MC3). Society for Reproduction and Fertility. Sutton Bonnington 11th - 13th July 2010

Independent influences of sex steroids of systemic and central origin in a rat model of Parkinson's disease: a contribution to sex-specific neuroprotection by estrogens

Article

Gillies, G.E. and McArthur, S. 2010. Independent influences of sex steroids of systemic and central origin in a rat model of Parkinson's disease: a contribution to sex-specific neuroprotection by estrogens. Hormones and behavior. 57 (1), pp. 23-34. https://doi.org/10.1016/j.yhbeh.2009.06.002

Fabrication of a novel poly(3-hydroxyoctanoate) / nanoscale bioactive glass composite film with potential as a multifunctional wound dressing

Conference paper

Rai, R., Boccaccini, A.R., Knowles, J.C., Locke, I.C., Gordge, M.P., McCormick, A., Salih, V., Mordon, N., Keshavarz, T. and Roy, I. 2010. Fabrication of a novel poly(3-hydroxyoctanoate) / nanoscale bioactive glass composite film with potential as a multifunctional wound dressing. 5th international conference on times of polymers (TOP) and composites. Ischia, Italy 20–23 June 2010 https://doi.org/10.1063/1.3455552

Exquisite sensitivity to subsecond, picomolar nitric oxide transients conferred on cells by guanylyl cyclase-coupled receptors

Article

Batchelor, A.M., Bartus, K., Reynell, C., Constantinou, S., Halvey, E.J., Held, K.F., Dostmann, W.R., Vernon, J. and Garthwaite, J. 2010. Exquisite sensitivity to subsecond, picomolar nitric oxide transients conferred on cells by guanylyl cyclase-coupled receptors. Proceedings of the National Academy of Sciences of the United States of America. 107 (51), pp. 22060-22065. https://doi.org/10.1073/pnas.1013147107

Virus neutralising activity of African fruit bat (Eidolon helvum) sera against emerging lyssaviruses

Article

Wright, E., Hayman, D.T.S., Vaughan, A., Temperton, N.J., Wood, J.L.N., Cunningham, A.A., Suu-Ire, R., Weiss, R.A. and Fooks, A.R. 2010. Virus neutralising activity of African fruit bat (Eidolon helvum) sera against emerging lyssaviruses. Virology. 408 (2), pp. 183-189. https://doi.org/10.1016/j.virol.2010.09.014

Polymorphism of amyloid-ß fibrils and its effects on human erythrocyte catalase binding

Article

Milton, N.G.N. and Harris, J.R. 2009. Polymorphism of amyloid-ß fibrils and its effects on human erythrocyte catalase binding. Micron. 40 (8), pp. 800-810. https://doi.org/10.1016/j.micron.2009.07.006

A robust lentiviral pseudotype neutralisation assay for in-field serosurveillance of rabies and lyssaviruses in Africa

Article

Wright, E., McNabb, S., Goddard, T., Horton, D.L., Lembo, T., Nel, L.H., Weiss, R.A., Cleaveland, S. and Fooks, A.R. 2009. A robust lentiviral pseudotype neutralisation assay for in-field serosurveillance of rabies and lyssaviruses in Africa. Vaccine. 27 (51), pp. 7178-7186. https://doi.org/10.1016/j.vaccine.2009.09.024

Mechanisms of activity-dependent plasticity in cellular nitric oxide-cGMP signaling

Article

Halvey, E.J., Vernon, J., Roy, B. and Garthwaite, J. 2009. Mechanisms of activity-dependent plasticity in cellular nitric oxide-cGMP signaling. Journal of Biological Chemistry. 284 (38), pp. 25630-25641. https://doi.org/10.1074/jbc.M109.030338

Emerging technologies for the detection of rabies virus: challenges and hopes in the 21st century

Journal article

Fooks, A.R., Johnson, N., Freuling, C.M., Wakeley, P.R., Banyard, A.C., McElhinney, L.M., Marston, D.A., Dastjerdi, A., Wright, E., Weiss, R.A. and Muller, T. 2009. Emerging technologies for the detection of rabies virus: challenges and hopes in the 21st century. PLoS Neglected Tropical Diseases. 3 (9) e530. https://doi.org/10.1371/journal.pntd.0000530

Characterization of Bacillus and related species isolated from human faeces

Conference poster

Honda, H., Hoyles, L., Logan, N.A., Halket, G., La Ragione, R.M. and McCartney, A.L. 2009. Characterization of Bacillus and related species isolated from human faeces. 5th International Yakult Symposium: the Gut and More; Probiotic Influences Beyond the Gut. Amsterdam, Netherlands 18 Jun 2009

Cromoglycate drugs suppress eicosanoid generation in U937 cells by promoting the release of Anx-A1

Article

Yazid, S., Solito, E., Christian, H.C., McArthur, S., Goulding, N. and Flower, R.J. 2009. Cromoglycate drugs suppress eicosanoid generation in U937 cells by promoting the release of Anx-A1. Biochemical Pharmacology. 77 (12), pp. 1814-1826. https://doi.org/10.1016/j.bcp.2009.03.010

In vitro investigations into the effect of orlistat, an anti-obesity therapy, on the human fecal microbiota

Conference poster

Hoyles, L., Daggy, B.P., McKain, N., Wallace, R.J., Gibson, G.R. and McCartney, A.L. 2009. In vitro investigations into the effect of orlistat, an anti-obesity therapy, on the human fecal microbiota. American Society for Microbiology, 109th General Meeting. Philadelphia, USA 17 May 2009

Characterisation of cystathionine gamma-lyase/hydrogen sulphide pathway in ischaemia/reperfusion injury of the mouse kidney: an in vivo study

Article

Tripatara, P., Patel, N.S.A., Brancaleone, V., Renshaw, D., Rocha, J., Sepodes, B., Mota-Filipe, H., Perretti, M. and Thiemermann, C. 2009. Characterisation of cystathionine gamma-lyase/hydrogen sulphide pathway in ischaemia/reperfusion injury of the mouse kidney: an in vivo study. European Journal of Pharmacology. 606 (1-3), pp. 205-209. https://doi.org/10.1016/j.ejphar.2009.01.041

In vitro examination of the effect of orlistat on the ability of the faecal microbiota to utilize dietary lipids

PhD thesis

Hoyles, L. 2009. In vitro examination of the effect of orlistat on the ability of the faecal microbiota to utilize dietary lipids. PhD thesis University of Reading Food and Nutritional Biosciences

What do we mean when we refer to Bacteroidetes populations in the human gastrointestinal microbiota?

Article

Hoyles, L. and McCartney, A.L. 2009. What do we mean when we refer to Bacteroidetes populations in the human gastrointestinal microbiota? FEMS Microbiology Letters. 299 (2), pp. 175-183. https://doi.org/10.1111/j.1574-6968.2009.01741.x

A robust lentiviral pseudotype neutralisation assay for rabies and lyssavirus serology

Conference paper

Wright, E., Temperton, N.J., Weiss, R.A., McNabb, S., Lembo, T., Cleaveland, S., Marston, D.A., Horton, D.L., McElhinney, L.M. and Fooks, A.R. 2009. A robust lentiviral pseudotype neutralisation assay for rabies and lyssavirus serology. Rabies In The Americas XX. Quebec, Canada 2009

The implications for ‘in-field’ sero-surveillance and evaluation of vaccines targeting rabies using lacZ based lentiviral pseudotypes

Conference paper

Wright, E., McNabb, S., Goddard, T., Horton, D.L., Weiss, R.A., Cleaveland, S. and Fooks, A.R. 2009. The implications for ‘in-field’ sero-surveillance and evaluation of vaccines targeting rabies using lacZ based lentiviral pseudotypes. Society For General Microbiology Spring 2009 Meeting. Harrogate, UK 2009

Retroviral pseudotypes

Book chapter

Temperton, N.J. and Wright, E. 2009. Retroviral pseudotypes. in: Encyclopaedia of Life Sciences Chichester Wiley.

The antrums of ovine ovarian preovulatory follicles are severely hypoxic

Conference paper

Murray, J.F., Gillies, R.M., Carter, N.D. and Robinson, S.P. 2009. The antrums of ovine ovarian preovulatory follicles are severely hypoxic. Proceedings of the Society For Reproduction and Fertility Annual Conference. Oxford 12-14 July 2009 pp. 38

Annexin A1 regulates hormone exocytosis through a mechanism involving actin reorganization

Article

McArthur, S., Yazid, S., Christian, H.C., Sirha, R., Flower, R.J., Buckingham, J.C. and Solito, E. 2009. Annexin A1 regulates hormone exocytosis through a mechanism involving actin reorganization. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 23 (11), pp. 4000-4010. https://doi.org/10.1096/fj.09-131391

Identification of a sub-population of pituitary lactotroph cells in mice required for the normal luteotrophic function of prolactin

Conference poster

Jaubert, A., Fernadez-Fuente, M., Carmignac, D., Murray, J.F., Christain, H. and Le Tissier, P. 2009. Identification of a sub-population of pituitary lactotroph cells in mice required for the normal luteotrophic function of prolactin. ENDO2009. Washington 10-13 June 2009

Molecular characterization of the melanocortin 3 receptor in the testes of mice

Article

Horanin, M.M., Akindele, K., Getting, S.J., Smith, C.L. and Murray, J.F. 2009. Molecular characterization of the melanocortin 3 receptor in the testes of mice. pA2 Online. From the Queen Elizabeth II Conference Centre London, Winter 2009 Meeting: Proceedings of the British Pharmacological Society. 7 (4). https://doi.org/http://www.pa2online.org/abstracts/Vol7Issue4abst089P.pdf

Intraovarian changes associated with hypoxia during the rat oestrous cycle

Conference paper

Gillies, R.M., Carter, N.D., Robinson, S.P., McPhail, L.D. and Murray, J.F. 2009. Intraovarian changes associated with hypoxia during the rat oestrous cycle. National Ovarian Workshop. Fitzwilliam College, Cambridge 12-13 September 2009.

Hepatic oxidative stress and apoptosis following acute alcohol

Article

Everitt, H.E., Tewfik, I., Preedy, V.R. and Patel, V. 2009. Hepatic oxidative stress and apoptosis following acute alcohol. Alcohol & Alcoholism. 44, p. p85.


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