Hyppönen, E., Fararouei, M., Sovio, U., Hartikainen, A.L., Pouta, A., Robertson, C.E., Whittaker, J.C. and Jarvelin, M.R. 2011. High-dose vitamin D supplements are not associated with linear growth in a large Finnish cohort. Journal of Nutrition. 141 (5), pp. 843-848. https://doi.org/10.3945/jn.110.133009
| Title | High-dose vitamin D supplements are not associated with linear growth in a large Finnish cohort |
|---|---|
| Authors | Hyppönen, E., Fararouei, M., Sovio, U., Hartikainen, A.L., Pouta, A., Robertson, C.E., Whittaker, J.C. and Jarvelin, M.R. |
| Abstract | High vitamin D intake in childhood has been suggested to have an adverse influence on linear growth. In Finland, in the mid-1960s the official recommendation for infant vitamin D supplementation was 2000 IU/d (50 μg/d). We investigated whether high-dose vitamin D supplementation in infancy was associated with subsequent growth in height. We used data from a prospective population-based birth cohort study including all children due to be born in the 2 northernmost provinces in Finland in 1966 (12,058 live-births, coverage 96%). Information on each participant’s height was collected at birth and ages 1, 14, and 31 y, as were possible confounding factors (data for analyses available from 10,060 singletons). Information on the frequency and dose of vitamin D supplementation was collected in 1967 when participants were 1 y of age. A weak association was found between frequency of vitamin D supplementation with greater height at age 1 y (P = 0.005), which was explained by birth characteristics and maternal and social factors (adjusted P = 0.34). Neither frequency nor dose of vitamin D supplementation was associated with height at 14 or 31 y (P > 0.13). To conclude, contrary to proposed evidence suggesting that vitamin D has a negative influence on growth rate at a dosage of ~2000 IU/d, supplementation at this level in the Northern Finland Birth Cohort was not associated with reduced height at any age studied. |
| Journal | Journal of Nutrition |
| Journal citation | 141 (5), pp. 843-848 |
| ISSN | 0022-3166 |
| Year | 2011 |
| Publisher | American Society for Nutrition |
| Digital Object Identifier (DOI) | https://doi.org/10.3945/jn.110.133009 |
| Web address (URL) | http://dx.doi.org/10.3945/jn.110.133009 |
| Publication dates | |
| Published | 2011 |
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Digital Accessibility Symposium
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CYGNA: Power of Neurodiversity
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Prostate Cancer in Black Musicians
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24-hour exams – blessing in disguise for inclusive assessments or a logistical nightmare for higher education?
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Serum IgA1 shows increased levels of α 2,6-linked sialic acid in breast cancer
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Cadherin-5: a biomarker for metastatic breast cancer with optimum efficacy in oestrogen receptor-positive breast cancers with vascular invasion
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The Breast Cancer Cookbook
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An investigation of the protective effect of alpha+-thalassaemia against severe Plasmodium falciparum amongst children in Kumasi, Ghana
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Maternal nutrition: building foundations of long term good health
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The DietCompLyf study: a prospective cohort study of breast cancer survival and phytoestrogen consumption
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The DietCompLyf study: a prospective longitudinal study of breast cancer survival
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DietCompLyf study: a multi-centre UK study on breast cancer. What are the dietary and lifestyle changes following diagnosis?
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Do public health messages impact on knowledge, diet and lifestyle choices of women during pregnancy?
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Alpha thalassaemia and the severity of Plasmodium falciparum infection in microcytic children from the Ashanti region of Ghana
Opoku-Okrah, C., Smith, C.L., Gordge, M.P., Parry, M., Robertson, C.E., Abgenyega, T. and Nakua, E. 2012. Alpha thalassaemia and the severity of Plasmodium falciparum infection in microcytic children from the Ashanti region of Ghana. British Society for Haematology 52nd meeting. Glasgow 16-18 April 2012
A comparison of self-reported analgesic use and detection of urinary ibuprofen and acetaminophen metabolites by means of metabonomics
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Sugar-sweetened beverage, sugar intake of individuals, and their blood pressure: international study of macro/micronutrients and blood pressure
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Abstract B76 - An overview of the DietCompLyf study - a multicentre UK study to evaluate the role of diet, lifestyle and complementary medicine use on breast cancer recurrence
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Maternal haemoglobin during pregnancy and offspring's educational achievement: a prospective cohort study over 30 years
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A new food frequency questionnaire designed to measure the intake of fatty acids and antioxidants in children
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Dietary starch intake of individuals and their blood pressure: the international study of macronutrients and micronutrients and blood pressure
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Relationship of dietary linoleic acid to blood pressure: the international study of macro-micronutrients and blood pressure study
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Dietary and supplemental iron, red meat, and blood pressure: INTERMAP study
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The application of post-market monitoring to novel foods
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Relationship of glycaemic index with cardiovascular risk factors: analysis of the National Diet and Nutrition Survey for people aged 65 and older
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Dietary carbohydrate intake of individuals (total, starch, total sugar) and their blood pressure: INTERMAP study
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Post-market monitoring: Why? What? How?
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Biomarkers for nutrient-gene interactions
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Attainment of precision in implementation of 24 h dietary recalls: INTERMAP UK
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Salt intake and cardiovascular health in adults: analysis of INTERMAP study and NDNS
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Post-market surveillance of novel foods
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Book review: When food kills: BSE, E coli and disaster science
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Standardised coding of diet records: experiences from INTERMAP UK
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Surveillance and post market monitoring of potential health effects of novel (including GM) foods: feasibility study
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INTERMAP: the dietary data - process and quality control
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Enhancing data on nutrient composition of foods eaten by participants in the INTERMAP study in China, Japan, the United Kingdom, and the United States
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Tracing ingestion of 'novel' foods in UK diets for possible health surveillance: a feasibility study
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Book review: McCance and Widdowson's the composition of foods - sixth summary edition
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Higher blood pressure in middle-aged American adults with less education - role of multiple dietary factors: the INTERMAP study
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