Title | Prevalence, co-existence, and factors related to a change in geriatric giant syndromes over 2 years: results of the Second Wave of Cognition of Older People, Education, Recreational Activities, NutritIon, Comorbidities, fUnctional Capacity Studies (COPERNICUS) |
---|
Authors | Agnieszka Kujawska, Sławomir Kujawski, Jūratė Zupkauskienė, Jakub Husejko, Weronika Hajec, Claire E. Robertson, Mitchell G. Miglis, Nicholas McMahon, Melanie Dani, José Augusto Simões, Paweł Zalewski and Kornelia Kędziora-Kornatowska |
---|
Abstract | Background: We prospectively examined the prevalence, co-existence, and change of geriatric giant syndromes in older people over 2 years. Methods: Two hundred-five older subjects were examined before and after two years. Ten geriatric giants were assessed at both time points: cognitive impairment, depression, orthostatic hypotension, polypharmacy, sarcopenia, dynapenia, falls, chronic pain, fecal and urinary incontinence. Results: Chronic pain, cognitive impairment, and urinary incontinence were three of the most commonly occurring geriatric giants at baseline (57%, 46%, and 40%. The presence of fecal incontinence, urinary incontinence, falls, depression, cognitive impairment, orthostatic hypotension, and polypharmacy was most strongly related to the number of geriatric giants in total at baseline (p<0.05). A higher intake of dietary antioxidants by one point was related to fewer geriatric giants after two years (by 0.04, after adjusting for confounding factors (p=0.03)). Conclusions: Geriatric giant syndromes tend to coexist and change with high variability over two years. Higher intake of antioxidants with diet could be related to fewer geriatric giants over time. |
---|