Production of biopharmaceuticals through microbial cell immobilization

Keshavarz, T. 2005. Production of biopharmaceuticals through microbial cell immobilization. in: Nedovic, V. and Willaert, R. (ed.) Applications of cell immobilisation biotechnology Dordrecht, Germany Springer.

Chapter titleProduction of biopharmaceuticals through microbial cell immobilization
AuthorsKeshavarz, T.
EditorsNedovic, V. and Willaert, R.
Book titleApplications of cell immobilisation biotechnology
Year2005
PublisherSpringer
Publication dates
Published2005
Place of publicationDordrecht, Germany
SeriesFocus on biotechnology
ISBN1402032293
Journal citation(8B), pp. 407-420

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Simultaneous co-metabolic decolourisation of azo dye mixtures and bio-electricity generation under thermophillic (50°C) and saline conditions by an adapted anaerobic mixed culture in microbial fuel cells
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Novel biodegradable and biocompatible poly(3-hydroxyoctanoate)/bacterial cellulose composites
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Is quorum sensing involved in lovastatin production in the filamentous fungus Aspergillus terreus?
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Enhanced production of the polyhydroxyalkanoate, P(3HB), from cacillus cereus SPV and its applications in cartilage regeneration
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Enhanced bio-decolourisation of acid orange 7 by Shewanella oneidensis through co-metabolism in a microbial fuel cell
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The homopolymer poly(3-hydroxyoctanoate) as a matrix material for soft tissue engineering
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Polyhydroxyalkanoate (PHA): bacterial cellulose composites for biomedical applications
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Controlled delivery of gentamicin using poly(3-hydroxybutyrate) microspheres
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Impact of linoleic acid supplementation on lovastatin production in Aspergillus terreus cultures
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Enhanced and economical production of poly(3-hydroxybutyrate), a biodegradable polymer and its applications
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Quorum sensing as a method for improving sclerotiorin production in Penicillium sclerotiorum
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Fabrication of a novel poly(3-hydroxyoctanoate) / nanoscale bioactive glass composite film with potential as a multifunctional wound dressing
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Polyhydroxyalkanoates: bioplastics with a green agenda
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Production of polyhydroxyalkanoates: the future green materials of choice
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Microbial quorum sensing: a tool or a target for antimicrobial therapy?
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Quantitative PCR study on the mode of action of oligosaccharide elicitors on penicillin G production by Penicillium chrysogenum
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Effect of impeller speed and pH on the production of Poly(3-hydroxybutyrate) using Bacillus cereus SPV
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Elicitation effects of oligosaccharides on the transcriptional level of bacitracin ABC transporter genes in Bacillus licheniformis
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Dye decolorisation by laccase entrapped in copper alginate
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Towards higher laccase activities produced by aquatic ascomycetous fungi through combination of elicitors and an alternative substrate
Junghanns, C., Parra, R., Keshavarz, T. and Schlosser, D. 2008. Towards higher laccase activities produced by aquatic ascomycetous fungi through combination of elicitors and an alternative substrate. Engineering in Life Sciences. 8 (3), pp. 277-285.

Microbial biosynthesis of PHAs and its applications
Roy, I., Philip, S.E., Francis, L., Rai, R., Valappil, S.P., Markiv, A., Keshavarz, T., Misra, S.K., Decheng, M. and Boccaccini, A.R. 2008. Microbial biosynthesis of PHAs and its applications. COST Action 868: Biotechnical Functionalisation of Renewable Polymeric Materials: 2008 Annual Workshop (combined Working Group and Management Committee meeting). Varna, Bulgaria 18 -19 Sep 2008

Microbial PHA biosynthesis and its applications
Roy, I., Philip, S.E., Francis, L., Rai, R., Valappil, S.P., Markiv, A., Keshavarz, T., Misra, S.K., Decheng, M. and Boccaccini, A.R. 2008. Microbial PHA biosynthesis and its applications. 11th International Symposium on Biodegradable Polyesters. Massey University in Auckland, New Zealand 23 - 26 Nov 2008

Production of medium chain length polyhydroxyalkanoates using Pseudomonas species
Rai, R., Keshavarz, T. and Roy, I. 2008. Production of medium chain length polyhydroxyalkanoates using Pseudomonas species. 11th International Symposium on Biodegradable Polyesters. Massey University in Auckland, New Zealand 23 - 26 Nov 2008

Polyhydroxyalkanoate synthase in Bacillus cereus SPV, a class IV PHA synthase
Philip, S.E., Odell, M., Keshavarz, T. and Roy, I. 2008. Polyhydroxyalkanoate synthase in Bacillus cereus SPV, a class IV PHA synthase. 11th International Symposium on Biodegradable Polyesters. Massey University in Auckland, New Zealand 23 - 26 Nov 2008

Optimisation studies of multiple elicitor addition in microbial systems: P.Chrysogenum and B.Lichiniformis
Nair, R.R., Murphy, T., Roy, I., Harrop, A., Dixon, K. and Keshavarz, T. 2008. Optimisation studies of multiple elicitor addition in microbial systems: P.Chrysogenum and B.Lichiniformis. in: Marino, G., Bardone, E. and Viglia, A. (ed.) IBIC2008 - 1st International Conference on Industrial Biotechnology AIDIC Servizi S.r.l..

Polyhydroxyalkanoate synthasis using Bacillus cereus SPV
Francis, L., Keshavarz, T. and Roy, I. 2008. Polyhydroxyalkanoate synthasis using Bacillus cereus SPV. COST Action 868: Biotechnical Functionalisation of Renewable Polymeric Materials: 2008 Annual Workshop (combined Working Group and Management Committee meeting). Varna, Bulgaria 18 -19 Sep 2008

Large-scale production and efficient recovery of PHB with desirable material properties, from the newly characterised Bacillus cereus SPV
Valappil, S.P., Misra, S.K., Boccaccini, A.R., Keshavarz, T., Bucke, C. and Roy, I. 2007. Large-scale production and efficient recovery of PHB with desirable material properties, from the newly characterised Bacillus cereus SPV. Journal of Biotechnology. 132 (3), pp. 251-258.

Effect of oligosaccharide elicitors on bacitracin A production and evidence of transcriptional level control
Keshavarz, T., Murphy, T., Roy, I., Harrop, A. and Dixon, K. 2007. Effect of oligosaccharide elicitors on bacitracin A production and evidence of transcriptional level control. Journal of Biotechnology. 131 (4), pp. 397-403.

Effect of mannan oligosaccharide elicitor and ferulic acid on enhancement of laccases production in liquid cultures of basidiomycetes
Vanhulle, S., Radman, R., Parra, R., Cui, T., Bols, C.M., Tron, T., Sannia, G. and Keshavarz, T. 2007. Effect of mannan oligosaccharide elicitor and ferulic acid on enhancement of laccases production in liquid cultures of basidiomycetes. Enzyme and Microbial Technology. 40 (7), pp. 1712-1718.

Novel application of oligosaccharides as elicitors for the enhancement of bacitracin A production in cultures of Bacillus licheniformis
Murphy, T., Parra, R., Radman, R., Roy, I., Harrop, A., Dixon, K. and Keshavarz, T. 2007. Novel application of oligosaccharides as elicitors for the enhancement of bacitracin A production in cultures of Bacillus licheniformis. Enzyme and Microbial Technology. 40 (6), pp. 1518-1523.

Polyhydroxyalkanoates: biodegradable polymers with a range of applications
Philip, S.E., Keshavarz, T. and Roy, I. 2007. Polyhydroxyalkanoates: biodegradable polymers with a range of applications. Journal of Chemical Technology and Biotechnology. 82 (3), pp. 233-247.

Polyhydroxyalkanoates: biodegradable polymers with a range of applications
Philip, S.E., Keshavarz, T. and Roy, I. 2007. Polyhydroxyalkanoates: biodegradable polymers with a range of applications. Journal of Chemical Technology and Biotechnology. 82 (3), pp. 233-247.

Production of Polyhydroxyalkanoates from Bacillus cereus SPV under different nutrient limiting conditions
Rai, R., Padinhara, S.V., Keshavarz, T. and Roy, I. 2007. Production of Polyhydroxyalkanoates from Bacillus cereus SPV under different nutrient limiting conditions. COST Action 868: Biotechnical Functionalisation of Renewable Polymeric Materials: first annual workshop. Graz, Austria 12 - 14 Sep 2007

Production of medium chain length polyhydroxyalkanoates using pseudomonas species UOW0417398
Rai, R., Keshavarz, T. and Roy, I. 2007. Production of medium chain length polyhydroxyalkanoates using pseudomonas species UOW0417398. International Conference on Biodegradable Polymers: their production, characterisation and application. SCI, London 10 Dec 2007

Polyhydroxy-alkanoates - the biodegradable polymers
Philip, S.E., Odell, M., Keshavarz, T. and Roy, I. 2007. Polyhydroxy-alkanoates - the biodegradable polymers. International Conference on Biodegradable Polymers: their production, characterisation and application. SCI, London 10 Dec 2007

Biosynthesis of polyhydroxyalkanoates and their applications
Francis, L., Keshavarz, T. and Roy, I. 2007. Biosynthesis of polyhydroxyalkanoates and their applications. International Conference on Biodegradable Polymers: their production, characterisation and application. SCI, London 10 Dec 2007

Effects of oligosaccharides and polysaccharides on the generation of reactive oxygen species in different biological systems
Radman, R., Bland, E.J., Sangworachat, N., Bucke, C. and Keshavarz, T. 2006. Effects of oligosaccharides and polysaccharides on the generation of reactive oxygen species in different biological systems. Biotechnology and Applied Biochemistry. 44 (3), pp. 129-133.

Cell immobilization: past, present and future prospects
Keshavarz, T. and Nedovic, V. 2006. Cell immobilization: past, present and future prospects. Journal of Chemical Technology and Biotechnology. 81 (4), pp. 483-484.

Specificities of proteases for use in leather manufacture
Foroughi, F., Keshavarz, T. and Evans, C.S. 2006. Specificities of proteases for use in leather manufacture. Journal of Chemical Technology and Biotechnology. 81 (3), pp. 257-261.

Comparative studies on the influence of higher basidiomycetes polysaccharide fractions on reactive oxidizing species production
Lakkireddy, G., Keshavarz, T. and Bucke, C. 2006. Comparative studies on the influence of higher basidiomycetes polysaccharide fractions on reactive oxidizing species production. International Journal of Medicinal Mushrooms. 8 (2), pp. 135-148.

Biological activity of industrial wood and bark waste from Pinus nigra
Curras Lino, M., Radman, R., Bertaud, F., Nisula, L., Lenon, G., Holbom, B., Locke, I.C., Thompson, S. and Keshavarz, T. 2006. Biological activity of industrial wood and bark waste from Pinus nigra. in: Actual problems of creation of new medicinal preparations of natural origin: the 10th international congress PHYTOPHARM 2006, St.-Petersburg, June 27-30, 2006: proceedings of congress St Petersburg, Russia PHYTOPHARM. pp. 401-403

Polyhydroxyalkanoate synthases: the enzymes involved in biodegradable polymer synthesis
Valappil, S.P., Philip, S.E., Odell, M., Keshavarz, T. and Roy, I. 2005. Polyhydroxyalkanoate synthases: the enzymes involved in biodegradable polymer synthesis. Proceedings of Frontiers in Chemical Biology: Mechanistic Enzymology and Biocatalysis. Exeter, UK 31 Aug - 02 Sep 2005

Large scale production of P(3HB) from newly isolated Bacillus sp.
Valappil, S.P., Keshavarz, T., Bucke, C. and Roy, I. 2005. Large scale production of P(3HB) from newly isolated Bacillus sp. Proceedings of the 1st International Conference on Environmental Industrial and Applied Microbiology. Badajoz, Spain 15 - 18 Mar 2005

Towards unravelling the elicitation mechanism in cultures of Penicillium chrysogenin: Chrysogenin elicitation
Nair, R.R., Radman, R., Roy, I., Bucke, C. and Keshavarz, T. 2005. Towards unravelling the elicitation mechanism in cultures of Penicillium chrysogenin: Chrysogenin elicitation. in: Pierucci, S. (ed.) 7th Italian Conference on Chemical and Process Engineering: ICheaP 7, May 15-16, 2005, Giardini Di Naxos, Italy Italy Associazione Italiana Di Ingegneria Chimica.

Elicitor effects on Penicillium chrysogenum morphology in submerged cultures
Radman, R., Bucke, C. and Keshavarz, T. 2004. Elicitor effects on Penicillium chrysogenum morphology in submerged cultures. Biotechnology and Applied Biochemistry. 40 (3), pp. 229-233.

The influence of small oligosaccharides on the immune system
Bland, E.J., Keshavarz, T. and Bucke, C. 2004. The influence of small oligosaccharides on the immune system. Carbohydrate Research. 339 (10), pp. 1673-1678.

Morphological changes in the submerged cultures of Penicillium chrysogenum: elicitor effects
Radman, R., Bucke, C. and Keshavarz, T. 2004. Morphological changes in the submerged cultures of Penicillium chrysogenum: elicitor effects. in: Pierucci, S. (ed.) 6th Italian Conference on Chemical and Process Engineering: ICheaP 6, June 8-11, 2003, Pisa, Italy Italy Associazione Italiana Di Ingegneria Chimica.

Elicitor effects on reactive oxygen species in liquid cultures of Penicillium chrysogenum
Radman, R., Bucke, C. and Keshavarz, T. 2004. Elicitor effects on reactive oxygen species in liquid cultures of Penicillium chrysogenum. Biotechnology Letters. 26 (2), pp. 147-152.

Elicitation of plants and microbial cell systems
Radman, R., Saez, T., Bucke, C. and Keshavarz, T. 2003. Elicitation of plants and microbial cell systems. Biotechnology and Applied Biochemistry. 37 (1), pp. 91-102.

Transformation of high concentrations of chlorophenols by the white-rot basidiomycete Trametes versicolor immobilized on nylon mesh
Sedarati, M.R., Keshavarz, T., Leontievsky, A. and Evans, C.S. 2003. Transformation of high concentrations of chlorophenols by the white-rot basidiomycete Trametes versicolor immobilized on nylon mesh. Electronic Journal of Biotechnology. 6 (2), pp. 104-114.

A process comparison between production of antibody fragments in E. coli and in Aspergillus awamori
Keshavarz, T. and Keshavarz-Moore, E. 2003. A process comparison between production of antibody fragments in E. coli and in Aspergillus awamori. in: Pierucci, S. (ed.) 6th Italian Conference on Chemical and Process Engineering: ICheaP 6, June 8-11, 2003, Pisa, Italy Italy Associazione Italiana Di Ingegneria Chimica.

Factors affecting the production of a single-chain antibody fragment by Aspergillus awamori in a stirred tank reactor
Sotiriadis, A., Keshavarz, T. and Keshavarz-Moore, E. 2001. Factors affecting the production of a single-chain antibody fragment by Aspergillus awamori in a stirred tank reactor. Biotechnology Progress. 17 (4), pp. 618-623.

Production of lipolytic enzymes in batch cultures of Ophiostoma piceae
Tamerler, C., Martinez, A. and Keshavarz, T. 2001. Production of lipolytic enzymes in batch cultures of Ophiostoma piceae. Journal of Chemical Technology and Biotechnology. 76 (9), pp. 991-996.

Effect of mannan and alginate oligosaccharides on production in bioreactors of penicillin G and its biosynthetic intermediates
Tamerler, C., Ariyo, B., Bucke, C. and Keshavarz, T. 2001. Effect of mannan and alginate oligosaccharides on production in bioreactors of penicillin G and its biosynthetic intermediates. Annals of Microbiology. 51 (1), pp. 53-60.

Effect of pH and loading manner on the start-up period of peat biofilter degrading xylene and toluene mixture
Marek, J., Paca, J., Halecky, M., Koutsky, B., Sobotka, M. and Keshavarz, T. 2001. Effect of pH and loading manner on the start-up period of peat biofilter degrading xylene and toluene mixture. Folia Microbiologica. 76 (9), pp. 205-209.

Using 2',7'-dichlorodihydrofluorescein-diacetate to assess polysaccharides as immunomodulating agents
Brand, E., Keshavarz, T. and Bucke, C. 2001. Using 2',7'-dichlorodihydrofluorescein-diacetate to assess polysaccharides as immunomodulating agents. Molecular Biotechnology. 19 (2), pp. 125-131.

Lipolytic enzyme production in batch and fed-batch cultures of Ophiostoma piceae and Fusarium oxysporum
Tamerler, C. and Keshavarz, T. 2000. Lipolytic enzyme production in batch and fed-batch cultures of Ophiostoma piceae and Fusarium oxysporum. Journal of Chemical Technology and Biotechnology. 75 (9), pp. 785-790.

Enhancement of chrysogenin production in cultures of Penicillium chrysogenum by uronic acid oligosaccharides
Asilonu, E., Bucke, C. and Keshavarz, T. 2000. Enhancement of chrysogenin production in cultures of Penicillium chrysogenum by uronic acid oligosaccharides. Biotechnology Letters. 22 (11), pp. 931-936.

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