Characteristics of antibodies to myeloperoxidase in vasculitic and non-vasculitic conditions

Locke, I.C., Leaker, B. and Cambridge, G. 1996. Characteristics of antibodies to myeloperoxidase in vasculitic and non-vasculitic conditions.

TitleCharacteristics of antibodies to myeloperoxidase in vasculitic and non-vasculitic conditions
AuthorsLocke, I.C., Leaker, B. and Cambridge, G.
TypeConference paper
Year1996
Publication dates
Published1996

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Urocortin – From Parkinson’s disease to the skeleton
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Poly(3-hydroxybutyrate)-ethyl cellulose based bio-composites with novel characteristics for infection free wound healing application
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Development of novel antibacterial active, HaCaT biocompatible and biodegradable CA-g-P(3HB)-EC biocomposites with caffeic acid as a functional entity
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Development of bio-composites with novel characteristics: Evaluation of phenol-induced antibacterial, biocompatible and biodegradable behaviours
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In-situ development of self-defensive antibacterial biomaterials: phenol-g-keratin-EC based bio-composites with characteristics for biomedical applications
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Anatomy, embryology, and cell families
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Melanocortin peptides protect chondrocytes from mechanically induced cartilage injury
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Novel Poly(3-hydroxyoctanoate)/Poly(3-hydroxybutyrate) blends for medical applications
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Urocortin is a novel regulator of osteoclast differentiation and function through inhibition of a canonical transient receptor potential 1-like cation channel
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Chondrocyte CRF receptor expression and Urocortin I mediated chondroprotection
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α-MSH and [DTRP]8-γ-MSH inhibit pro-inflammatory cytokine release from stimulated primary bovine chondrocytes
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MC1 and MC3 activation inhibits caspase-3 production and activity, promotes cell-viability, and induces IL-10 and HO-1 release from human C20/A4 chondrocytes
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The influence of tetracycline loading on the surface morphology and biocompatibility of films made from P(3HB) microspheres
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Fabrication of a novel poly(3-hydroxyoctanoate) / nanoscale bioactive glass composite film with potential as a multifunctional wound dressing
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Mechanisms of Urocortin family peptide mediated chondroprotection
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The effect of indentor shape on the creep curves of collagen gel
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Melanocortin peptides modulate pro-inflammatory mediator release from TNF-a stimulated C-20/A4 cells
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The MC3 agonist dTRP8-γ-MSH inhibits IL-6 and IL-8 release from TNF-α stimulated C-20/A4 chondrocytes, an effect blocked by the MC3R antagonist SHU9119
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Melanocortin peptide therapy for the treatment of arthritic pathologies
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Pro-inflammatory mediator release from TNF-α stimulated C-20/A4 cells results in Col II degradation
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Melanocortin peptides modulate pro-inflammatory mediator release from TNF-a stimulated C-20/A4 cells
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The corticotrophin-releasing factor-like peptide urocortin reverses key deficits in two rodent models of Parkinson's disease
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Interactions between cell surface protein disulphide isomerase and S-nitrosoglutathione during nitric oxide delivery
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Cytotoxicity of clove (Syzygium aromaticum) oil and its major components to human skin cells
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Biological activity of industrial wood and bark waste from Pinus nigra
Curras Lino, M., Radman, R., Bertaud, F., Nisula, L., Lenon, G., Holbom, B., Locke, I.C., Thompson, S. and Keshavarz, T. 2006. Biological activity of industrial wood and bark waste from Pinus nigra. in: Actual problems of creation of new medicinal preparations of natural origin: the 10th international congress PHYTOPHARM 2006, St.-Petersburg, June 27-30, 2006: proceedings of congress St Petersburg, Russia PHYTOPHARM. pp. 401-403

Interactions between cell surface protein disulphide isomerase and S-nitrosoglutathione during nitric oxide delivery into MEG-01 megakaryocytes
Shah, C.M., Walters, S.E., Locke, I.C., Chowdrey, H.S. and Gordge, M.P. 2005. Interactions between cell surface protein disulphide isomerase and S-nitrosoglutathione during nitric oxide delivery into MEG-01 megakaryocytes.

Evidence for a neuroprotective role of the CRH-like peptide, urocortin, in the 6-hydroxydopamine treated rat
Biggs, C.S., Locke, I.C., Knight, R.A., Chowdrey, H.S. and Whitton, P.S. 2005. Evidence for a neuroprotective role of the CRH-like peptide, urocortin, in the 6-hydroxydopamine treated rat.

Urocortin attenuates key indicators of nigrostriatal pathway destruction in a rat hemiparkinsonian model
Biggs, C.S., Abuirmeileh, A., Locke, I.C., Knight, R.A., Chowdrey, H.S. and Whitton, P.S. 2005. Urocortin attenuates key indicators of nigrostriatal pathway destruction in a rat hemiparkinsonian model. Proceedings of the British Pharmacological Society. 3 (4).

Functional characteristics of the streptococcal deoxyribonuclease 'streptodornase', a protein with DNase activity present in the medicament Varidase
Locke, I.C. and Carpenter, B.G. 2004. Functional characteristics of the streptococcal deoxyribonuclease 'streptodornase', a protein with DNase activity present in the medicament Varidase. Enzyme and Microbial Technology. 35 (1), pp. 67-73.

Cytotoxicity of lavender oil and its major components to human skin cells
Prashar, A., Locke, I.C. and Evans, C.S. 2004. Cytotoxicity of lavender oil and its major components to human skin cells. Cell Proliferation. 37 (3), pp. 221-229.

Cell surface thiol modification by GSNO: a mechanism of nitric oxide delivery?
Shah, C.M., Locke, I.C., Chowdrey, H.S. and Gordge, M.P. 2004. Cell surface thiol modification by GSNO: a mechanism of nitric oxide delivery?

Protein disulphide isomerase is involved in the delivery of NO from S-nitrosoglutathione into megakaryocytes
Shah, C.M., Locke, I.C., Chowdrey, H.S. and Gordge, M.P. 2004. Protein disulphide isomerase is involved in the delivery of NO from S-nitrosoglutathione into megakaryocytes.

Protein disulphide isomerase is involved in the delivery of NO from S-nitrosoglutathione into megakaryocytes
Shah, C.M., Locke, I.C., Chowdrey, H.S. and Gordge, M.P. 2004. Protein disulphide isomerase is involved in the delivery of NO from S-nitrosoglutathione into megakaryocytes.

Establishment and analysis of 3-D collagen cultures of C-20/A4 chondrocytes
Petsa, A., Chowdrey, H.S., Knight, R.A., Afoke, A. and Locke, I.C. 2004. Establishment and analysis of 3-D collagen cultures of C-20/A4 chondrocytes.

A CRH family peptide protects a human chondrocyte cell line against apoptosis
Intekhab-Alam, N.Y., Chowdrey, H.S., Knight, R.A., Locke, I.C. and Intekhab Alam, N.Y. 2004. A CRH family peptide protects a human chondrocyte cell line against apoptosis.

Rapid S-nitrosothiol metabolism by platelets and megakaryocytes
Shah, C.M., Locke, I.C., Chowdrey, H.S. and Gordge, M.P. 2003. Rapid S-nitrosothiol metabolism by platelets and megakaryocytes. Biochemical Society Transactions. 31 (6), pp. 1450-1452.

Role of protein disulphide isomerase in NO delivery from S-nitrosothiols into megakaryocytes
Shah, C.M., Locke, I.C., Chowdrey, H.S. and Gordge, M.P. 2003. Role of protein disulphide isomerase in NO delivery from S-nitrosothiols into megakaryocytes.

The behaviour of C-20/A4 chondrocytes in 3-D collagen gel cultures
Petsa, A., Afoke, A., Chowdrey, H.S., Knight, R.A., Harris, A. and Locke, I.C. 2003. The behaviour of C-20/A4 chondrocytes in 3-D collagen gel cultures.

Ion-dependency of the streptococcal deoxyribonuclease "streptodornase", an active constituent of the medicament Varidase
Locke, I.C. and Carpenter, B.G. 2002. Ion-dependency of the streptococcal deoxyribonuclease "streptodornase", an active constituent of the medicament Varidase. Enzyme and Microbial Technology. 31 (4), pp. 482-489.

Effect of essential oils and their components on cell
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Varidase: the science behind the medicament
Rutter, P.M., Carpenter, B.G., Hill, S.S. and Locke, I.C. 2000. Varidase: the science behind the medicament. Journal of Wound Care. 9 (5), pp. 223-226.

A comparison of the characteristics of circulating anti-myeloperoxidase antibodies in vasculitis with those in non-vasculitic conditions
Locke, I.C., Leaker, B. and Cambridge, G. 1999. A comparison of the characteristics of circulating anti-myeloperoxidase antibodies in vasculitis with those in non-vasculitic conditions. Clinical and Experimental Immunology. 115 (2), pp. 369-376.

A comparison of the variable region genes of two human monoclonal antibodies to myeloperoxidase
Locke, I.C., Rahman, M.A.A. and Cambridge, G. 1998. A comparison of the variable region genes of two human monoclonal antibodies to myeloperoxidase.

Adjacent proline residues in the inhibitory domain of the Oct-2 transcription factor play distinct functional roles
Liu, Y.Z., Lee, I.K., Locke, I.C., Dawson, S. and Latchman, D. 1998. Adjacent proline residues in the inhibitory domain of the Oct-2 transcription factor play distinct functional roles. Nucleic Acids Research. 26 (10), pp. 2464-2472.

Purification of a streptococcal deoxyribonuclease by affinity chromatography based on a DNA-cellulose matrix
Locke, I.C., Cox, S.F. and Carpenter, B.G. 1997. Purification of a streptococcal deoxyribonuclease by affinity chromatography based on a DNA-cellulose matrix. Journal of Chromatography A. 788 (1-2), pp. 75-80.

Autoantibodies to myeloperoxidase in systemic sclerosis
Locke, I.C., Worral, J.G., Leaker, B., Black, C.M. and Cambridge, G. 1997. Autoantibodies to myeloperoxidase in systemic sclerosis. Journal of Rheumatology. 24 (1), pp. 86-89.

Characteristics of anti-myeloperoxidase autoantibodies in vasculitis and other conditions
Locke, I.C., Leaker, B. and Cambridge, G. 1996. Characteristics of anti-myeloperoxidase autoantibodies in vasculitis and other conditions.

Autoantibodies to neutrophil granule proteins: pathogenic potential in vasculitis?
Locke, I.C. and Cambridge, G. 1996. Autoantibodies to neutrophil granule proteins: pathogenic potential in vasculitis? British Journal of Biomedical Science. 53 (4), pp. 302-316.

A human monoclonal anti-myeloperoxidase antibody can prime human neutrophils in vitro
Cambridge, G., Leaker, B., Locke, I.C., Noronha-Dutra, A. and Epperlein, M. 1996. A human monoclonal anti-myeloperoxidase antibody can prime human neutrophils in vitro.

Autoantibodies to myeloperoxidase in systemic sclerosis
Worral, J.G., Locke, I.C., Leaker, B., Black, C.M. and Cambridge, G. 1995. Autoantibodies to myeloperoxidase in systemic sclerosis.

Automated analysis of the deoxyribonuclease active constituents of the medicament Varidase ®
Locke, I.C., Ramsay, M.P., Hill, S.S. and Carpenter, B.G. 1993. Automated analysis of the deoxyribonuclease active constituents of the medicament Varidase ®. The Journal of Automatic Chemistry. 15, pp. 65-70.

Automated analysis of the deoxyribonuclease active constituents of the medicament Varidase ®
Locke, I.C., Ramsey, M.P., Hill, S.S. and Carpenter, B.G. 1992. Automated analysis of the deoxyribonuclease active constituents of the medicament Varidase ®.

Purification of the seed lectin from Dolichos biflorus by chromatofocusing
Rogers, D.J., Locke, I.C., Gibbs, R. and Carpenter, B.G. 1990. Purification of the seed lectin from Dolichos biflorus by chromatofocusing.

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