Correcting for non-participation bias in health surveys using record-linkage, synthetic observations and pattern mixture modelling

Gray, L., Gorman, E., White, I. R., Katikireddi, S. V., McCartney, G., Rutherford, L. and Leyland, A. H. 2020. Correcting for non-participation bias in health surveys using record-linkage, synthetic observations and pattern mixture modelling. Statistical Methods in Medical Research. 29 (4), pp. 1212-1226. https://doi.org/10.1177/0962280219854482

TitleCorrecting for non-participation bias in health surveys using record-linkage, synthetic observations and pattern mixture modelling
TypeJournal article
AuthorsGray, L., Gorman, E., White, I. R., Katikireddi, S. V., McCartney, G., Rutherford, L. and Leyland, A. H.
Abstract

Surveys are key means of obtaining policy-relevant information not available from routine sources. Bias arising from non-participation is typically handled by applying weights derived from limited socio-demographic characteristics. This approach neither captures nor adjusts for differences in health and related behaviours between participants and non-participants within categories. We addressed non-participation bias in alcohol consumption estimates using novel methodology applied to 2003 Scottish Health Survey responses record-linked to prospective administrative data. Differences were identified in socio-demographic characteristics, alcohol-related harm (hospitalisation or mortality) and all-cause mortality between survey participants and, from unlinked administrative sources, the contemporaneous general population of Scotland. These were used to infer the number of non-participants within each subgroup defined by socio-demographics and health outcomes. Synthetic observations for non-participants were then generated, missing only alcohol consumption. Weekly alcohol consumption values among synthetic non-participants were multiply imputed under missing at random and missing not at random assumptions. Relative to estimates adjusted using previously derived weights, the obtained mean weekly alcohol intake estimates were up to 59% higher among men and 16% higher among women, depending on the assumptions imposed. This work demonstrates the universal value of multiple imputation-based methodological advancement incorporating administrative health data over routine weighting procedures.

JournalStatistical Methods in Medical Research
Journal citation29 (4), pp. 1212-1226
Year2020
PublisherSage
Digital Object Identifier (DOI)https://doi.org/10.1177/0962280219854482
Web address (URL)https://journals.sagepub.com/doi/10.1177/0962280219854482
Publication dates
Published online11 Jun 2019
Published in print01 Apr 2020
FunderMRC (Medical Research Council)
LicenseCC BY 4.0

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