Picosecond Laser Ablation of Polyhydroxyalkanoates (PHAs): Comparative Study of Neat and Blended Material Response

Ortiz, R, Basnett, P., Roy, I. and Quintana, I. 2020. Picosecond Laser Ablation of Polyhydroxyalkanoates (PHAs): Comparative Study of Neat and Blended Material Response. e-Polymers. 12 (1) 127. doi:10.3390/polym12010127

TitlePicosecond Laser Ablation of Polyhydroxyalkanoates (PHAs): Comparative Study of Neat and Blended Material Response
TypeJournal article
AuthorsOrtiz, R, Basnett, P., Roy, I. and Quintana, I.
Abstract

Polyhydroxyalkanoates (PHAs) have emerged as a promising biodegradable and biocompatible material for scaffold manufacturing in the tissue engineering field and food packaging. Surface modification is usually required to improve cell biocompatibility and/or reduce bacteria proliferation. Picosecond laser ablation was applied for surface micro structuring of short- and medium-chain length-PHAs and its blend. The response of each material as a function of laser energy and wavelength was analyzed. Picosecond pulsed laser modified the surface topography without affecting the material properties. UV wavelength irradiation showed halved ablation thresholds compared to visible (VIS) wavelength, revealing a greater photochemical nature of the ablation process at ultraviolet (UV) wavelength. Nevertheless, the ablation rate and, therefore, ablation efficiency did not show a clear dependence on beam wavelength. The different mechanical behavior of the considered PHAs did not lead to different ablation thresholds on each polymer at a constant wavelength, suggesting the interplay of the material mechanical parameters to equalize ablation thresholds. Blended-PHA showed a significant reduction in the ablation threshold under VIS irradiation respect to the neat PHAs. Picosecond ablation was proved to be a convenient technique for micro structuring of PHAs to generate surface microfeatures appropriate to influence cell behavior and improve the biocompatibility of scaffolds in tissue engineering

Keywords polyhydroxyalkanoates (PHAs); picosecond pulsed laser ablation; surface micro structuring
Article number127
Journale-Polymers
Journal citation12 (1)
ISSN2073-4360
Year2019
PublisherMDPI
Publisher's version
License
CC BY 4.0
File Access Level
Open (open metadata and files)
Digital Object Identifier (DOI)doi:10.3390/polym12010127
Publication dates
Published05 Jan 2020
Supplemental file
File Access Level
Open (open metadata and files)

Related outputs

Comparison of the Influence of 45S5 and Cu-Containing 45S5 Bioactive Glass (BG) on the Biological Properties of Novel Polyhydroxyalkanoate (PHA)/BG Composites
Schuhladen, K., Lukasiewicz, B., Basnett, P., Roy, I. and Boccaccini, A.R. 2020. Comparison of the Influence of 45S5 and Cu-Containing 45S5 Bioactive Glass (BG) on the Biological Properties of Novel Polyhydroxyalkanoate (PHA)/BG Composites. Materials. 13 (11) 2607. doi:10.3390/ma13112607

Antimicrobial Materials with Lime Oil and a Poly (3-hydroxyalkanoate) Produced via Valorisation of Sugar Cane Molasses
Basnett, P., Marcello, E., Lukasiewicz, B., Nigmatullin, R., Paxinou, A., Ahmad, M.A., Gurumayum , B. and Roy, I. 2020. Antimicrobial Materials with Lime Oil and a Poly (3-hydroxyalkanoate) Produced via Valorisation of Sugar Cane Molasses. Journal of Functional Biomaterials. 11 (2) 24. doi:10.3390/jfb11020024

Esterase Cleavable 2D Assemblies of Magnetic Iron Oxide Nanocubes: Exploiting Enzymatic Polymer Disassembling to Improve Magnetic Hyperthermia Heat Losses
Avugadda, S.K., Materia, M.E., Nigmatullin, R., Cabrera, D., Marotta, R., Cabada, T.F., Marcello, E., Nitti, S., Artés-Ibañez, E.J., Basnett, P., Wilhelm, C., Teran, F.J., Roy, I. and Pellegrino, T. 2019. Esterase Cleavable 2D Assemblies of Magnetic Iron Oxide Nanocubes: Exploiting Enzymatic Polymer Disassembling to Improve Magnetic Hyperthermia Heat Losses. Chemistry of Materials. 31 (15), pp. 5450-5463. doi:10.1021/acs.chemmater.9b00728

Biosynthesis and characterization of a novel, biocompatible medium chain length polyhydroxyalkanoate by Pseudomonas mendocina CH50 using coconut oil as the carbon source
Basnett, P., Marcello, E., Lukasiewicz, B., Panchal, B., Nigmatullin, R., Knowles, J.C. and Roy, I. 2018. Biosynthesis and characterization of a novel, biocompatible medium chain length polyhydroxyalkanoate by Pseudomonas mendocina CH50 using coconut oil as the carbon source. Journal of Materials Science: Materials in Medicine. 29, p. 179 179. doi:10.1007/s10856-018-6183-9

In Vivo Tracking and 1H/19F Magnetic Resonance Imaging of Biodegradable Polyhydroxyalkanoate / Polycaprolactone Blend Scaffolds Seeded with Labeled Cardiac Stem Cells
Constantinides, C., Basnett, P., Lukasiewicz, B., Carnicer, R., Swider, E., Majid, Q.A., Srinivas, M., Carr, C.A. and Roy, I. 2018. In Vivo Tracking and 1H/19F Magnetic Resonance Imaging of Biodegradable Polyhydroxyalkanoate / Polycaprolactone Blend Scaffolds Seeded with Labeled Cardiac Stem Cells. ACS Applied Materials and Interfaces. 10 (30), p. 25056–25068. doi:10.1021/acsami.8b06096

Binary Polyhydroxyalkanoate Systems for Soft Tissue Engineering
Lukasiewicz, B., Basnett, P., Nigmatullin, R., Matharu, R., Knowles, J.C. and Roy, I. 2018. Binary Polyhydroxyalkanoate Systems for Soft Tissue Engineering. Acta Biomaterialia. 71, pp. 225-234. doi:10.1016/j.actbio.2018.02.027

Poly(3-hydroxyoctanoate), a promising new material for cardiac tissue engineering
Bagdadi, A., Safari, M., Dubey, P., Basnett, P., Sofokleous P., Humphrey E, Locke, I.C., Edirisinghe M., Terracciano C., Boccaccini, A.R., Knowles, J.C., Harding, S. and Roy, I. 2016. Poly(3-hydroxyoctanoate), a promising new material for cardiac tissue engineering. Journal of Tissue Engineering and Regenerative Medicine. 12 (1), pp. E495-E512. doi:10.1002/term.2318

Production of a novel medium chain length Poly(3-hydroxyalkanoate) using unprocessed biodiesel waste and its evaluation as a tissue engineering scaffold
Basnett, P., Lukasiewicz, B., Marcello, E., Kaur, H., Knowles, J.C. and Roy, I. 2017. Production of a novel medium chain length Poly(3-hydroxyalkanoate) using unprocessed biodiesel waste and its evaluation as a tissue engineering scaffold. Microbial Biotechnology. 10 (6), pp. 1384-1399. doi:10.1111/1751-7915.12782

Biosynthesis of polyhydroxyalkanoates, their novel blends and composites for biomedical applications
Basnett, P. 2014. Biosynthesis of polyhydroxyalkanoates, their novel blends and composites for biomedical applications. PhD thesis University of Westminster Faculty of Science and Technology

Novel Poly(3-hydroxyoctanoate)/Poly(3-hydroxybutyrate) blends for medical applications
Basnett, P., Ching, K.Y., Stolz, M., Knowles, J.C., Boccaccini, A.R., Smith, C.L., Locke, I.C., Keshavarz, T. and Roy, I. 2013. Novel Poly(3-hydroxyoctanoate)/Poly(3-hydroxybutyrate) blends for medical applications. Reactive and Functional Polymers. 73 (10), pp. 1340-1348. doi:10.1016/j.reactfunctpolym.2013.03.019

Aspirin-loaded P(3HO)/P(3HB) blend films: potential materials for biodegradable drug-eluting stents
Basnett, P., Ching, K.Y., Stolz, M., Knowles, J.C., Boccaccini, A.R., Smith, C.L., Locke, I.C. and Roy, I. 2013. Aspirin-loaded P(3HO)/P(3HB) blend films: potential materials for biodegradable drug-eluting stents. Bioinspired, Biomimetic and Nanobiomaterials. 2 (3), pp. 141-153. doi:10.1680/bbn.13.00009

Novel biodegradable and biocompatible poly(3-hydroxyoctanoate)/bacterial cellulose composites
Basnett, P., Knowles, J.C., Pishbin, F., Smith, C.L., Keshavarz, T., Boccaccini, A.R. and Roy, I. 2012. Novel biodegradable and biocompatible poly(3-hydroxyoctanoate)/bacterial cellulose composites. Advanced Engineering Materials. 14 (6), pp. B330-B343. doi:10.1002/adem.201180076

Polyhydroxyalkanoate (PHA): bacterial cellulose composites for biomedical applications
Basnett, P., Smith, C.L., Boccaccini, A.R., Knowles, J.C., Keshavarz, T. and Roy, I. 2011. Polyhydroxyalkanoate (PHA): bacterial cellulose composites for biomedical applications. European Society of Biomaterials. Dublin, Ireland Sept 2011

Production of polyhydroxyalkanoates and their medical applications
Roy, I., Akaraonye, E., Francis, L., Rai, R., Basnett, P. and Keshavarz, T. 2011. Production of polyhydroxyalkanoates and their medical applications. 7th International Conference on Polymer and Textile Biotechnology. Milan, Italy 2nd - 4th March 2011

Production of polyhydroxyalkanoates and their biomedical applications
Roy, I., Akaraonye, E., Francis, L., Rai, R., Basnett, P. and Keshavarz, T. 2011. Production of polyhydroxyalkanoates and their biomedical applications. Euro BioMat 2011 - European Symposium on Biomaterials and Related Areas. Jena, Germany

In vitro mutagenesis of the type IV polyhydroxyalkanoate synthase from bacillus cereus SPV
Basnett, P., Philip, S.E., Markhiv, A., Vydayanathan, A. and Roy, I. 2010. In vitro mutagenesis of the type IV polyhydroxyalkanoate synthase from bacillus cereus SPV. 12th International Symposium on Biodegradable Polyesters. Stuttgart, Germany.

Microbial production of biodegradable polymers and their role in cardiac stent development
Basnett, P. and Roy, I. 2010. Microbial production of biodegradable polymers and their role in cardiac stent development. in: Mendez-Vilas, A. (ed.) Current research, technology and education topics in applied microbiology and microbial biotechnology Formatex Research Center.

Biodegradable polymers and their role in coronary stent development
Basnett, P. and Roy, I. 2010. Biodegradable polymers and their role in coronary stent development. in: Current research in technology and education topics in applied microbiology and microbial biotechnology Formatex Research Center.

Permalink - https://westminsterresearch.westminster.ac.uk/item/qy7q3/picosecond-laser-ablation-of-polyhydroxyalkanoates-phas-comparative-study-of-neat-and-blended-material-response


Share this
Tweet
Email

Usage statistics

9 total views
7 total downloads
0 views this month
0 downloads this month
These values are for the period from September 2nd 2018, when this repository was created

Export as