Research Centre for Optimal Health

Gancitano, G., Mucci, N., Stange, R., Ogal, M., Vimalanathan, S., Sreya, M., Booker, A., Hadj-Cherif, B., Albrich, W., Woelkart-Ardjomand, K., Kreft, S., Vanden Berghe, W., Hoexter, G., Schapowal, A. and Johnston, S.L. 2024. Echinacea Reduces Antibiotics by Preventing Respiratory Infections: A Meta-Analysis (ERA-PRIMA). Antibiotics. 13 (4) 364. https://doi.org/10.3390/antibiotics13040364

Cresswell, E., Basty, N., Atabaki-Pasdar, N., Karpe, F. and Pinnick, K.E. 2024. The value of neck adipose tissue as a predictor for metabolic risk in health and type 2 diabetes. Biochemical Pharmacology. Advanced online publication. https://doi.org/10.1016/j.bcp.2024.116171

Abraham, Angela, Cule, M., Thanaj, M., Basty, N., Hashemloo, M.A., Sorokin, E., Whitcher, B., Burgess, S., Bell, J.D., Sattar, N., Thomas, E.L. and Yaghootkar, H. 2024. Genetic evidence for distinct biological mechanisms that link adiposity to type 2 diabetes: towards precision medicine. Diabetes. Advanced online publication. https://doi.org/10.2337/db23-1005

Smith, H.E., Mackenzie, A.M., Seddon, C., Mould, R., Kalampouka, I., Bateman, B., Needham, S.R., Beis, K., Bell, J.D., Nunn, A. and Botchway, S.W. 2024. The Use of NADH Anisotropy to Investigate Mitochondrial Cristae Alignment. Scientific Reports. 14 5980. https://doi.org/10.1038/s41598-024-55780-5

O'Donovan, S., Rundle, M., Thomas, E.L., Bell, J.D., Frost, G., Jacobs, D.M., Wanders, A., de Vries, R., Mariman, E.C.M., va Baak, M.A., Sterkman, L., Nieuwdorp, M., Groem, A.K., Arts, I.C.W., van Riel, N. and Afman, L.A. 2024. Quantifying the effect of nutritional interventions on metabolic resilience using personalised computational models. iScience. 27 (4) 109362. https://doi.org/10.1016/j.isci.2024.109362

Mould, R., Mackenzie, A.M., Kalampouka, I., Nunn, A., Thomas, E.L., Bell, J.D. and Botchway, S.W. 2024. Ultra Weak Photon Emission - A Brief Review. Frontiers in Physiology - Biophysics. 15 1348915. https://doi.org/10.3389/fphys.2024.1348915

Thanaj, M., Basty, N., Whitcher, B., Sorokin, E., Liu, Y., Srinivasan, R., Cule, M., Thomas, E.L. and Bell, J.D. 2024. Precision MRI phenotyping of muscle volume and quality at a population scale. Frontiers in Physiology. 15 1288657. https://doi.org/10.3389/fphys.2024.1288657

Mackenzie, A.M., Smith, H.E., Mould, R., Bell, J.D., Nunn, A. and Botchway, S.W. 2024. Rooting out ultraweak photon emission a-mung bean sprouts. Journal of Photochemistry and Photobiology. 19 100224. https://doi.org/10.1016/j.jpap.2023.100224

Thanaj, M., Basty, N., Cule, M., Sorokin, E., Whitcher, B., Bell, J.D. and Thomas, E.L. 2024. Liver Shape Analysis using Statistical Parametric Maps at Population Scale. BMC Medical Imaging. 24 15. https://doi.org/10.1186/s12880-023-01149-5

Thanaj, M., Basty, N., Cule, M., Sorokin, E., Whitcher, B., Srinivasan, R., Lennon, R., Bell, J.D. and Thomas, E.L. 2023. Kidney Shape Statistical Analysis: Associations with Disease and Anthropometric Factors. BMC Nephrology. 24 362. https://doi.org/10.1186/s12882-023-03407-8

Heymsfield, S., Bell, J.D. and Heber, D. 2023. Chapter 7: Phenotyping, Body Composition, and Precision Nutrition. in: Heber, D., Li, Z. and Ordovas, J. (ed.) Precision Nutrition: The Science and Promise of Personalized Nutrition and Health Academic Press. pp. 143-151

Mould, R., Kalampouka, I., Thomas, E.L., Guy, G., Nunn, A. and Bell, J.D. 2023. Non-chemical Signalling Between Mitochondria. Frontiers in Physiology. 14 1268075. https://doi.org/10.3389/fphys.2023.1268075

Rundle, M., Fiamoncini, J., Thomas, E.L., Wopereis, S., Afman, L.A., Brennan, L., Drevon, C.A., Gundersen, T.E., Daniel, H,, Garcia Perez, I., Posma, J.M., Ivanova, D.G., Bell, J.D., van Ommen, B. and Frost, G. 2023. Diet-induced weight loss and phenotypic flexibility among healthy overweight adults: a randomized trial . American Journal of Clinical Nutrition. 118 (3), pp. 591-604. https://doi.org/10.1016/j.ajcnut.2023.07.002

Thanaj, M., Basty, N., Cule, M., Sorokin, E., Whitcher, B., Srinivasan, R., Lennon, R., Bell, J.D. and Thomas, E.L. 2023. Preprint: Kidney Shape Statistical Analysis: Associations with Disease and Anthropometric Factors. medRxiv. https://doi.org/10.1101/2023.06.26.23291901

Dar, N.J., Bhat, S.A., Rehman, M.U. and Booker, A. 2023. Editorial: Investigating the molecular targets and therapeutic potential of Withania somnifera (Ashwagandha) in various pathophysiological conditions. Frontiers in Pharmacology. 14 1187334. https://doi.org/10.3389/fphar.2023.1187334

Basty, N., Sorokin, E., Thanaj, M., Srinivasan, R., Whitcher, B., Bell, J.D., Cule, M. and Thomas, E.L. 2023. Abdominal imaging associates body composition with COVID-19 severity. PLoS ONE. 18 (4) e0283506. https://doi.org/10.1371/journal.pone.0283506

Marjola Thanaj, Nicolas Basty, Brandon Whitcher, Elena P. Sorokin, Yi Liu, Ramprakash Srinivasan, Madeleine Cule, E. Louise Thomas and Jimmy D. Bell 2023. Preprint: Precision MRI phenotyping of muscle volume and quality at a population scale. medRxiv. https://doi.org/10.1101/2023.03.02.23286689

Nicolas Basty, Elena P. Sorokin, Marjola Thanaj, Brandon Whitcher, Yi Liu, Jimmy D. Bell, E. Louise Thomas and Madeleine Cule 2023. Preprint: Cardiovascular measures from abdominal MRI provide insights into abdominal vessel genetic architecture. medRxiv. https://doi.org/10.1101/2022.08.02.22278060

Basty, N., Thanaj, M., Cule, M., Sorokin, E., Liu, Y., Thomas, E.L., Bell, J.D. and Whitcher, B. 2023. Artifact-Free Fat-Water Separation in Dixon MRI using Deep Learning. Journal of Big Data. 10 4. https://doi.org/10.1186/s40537-022-00677-1

Allesøe, Rosa Lundbye, Lundgaard, A., Hernández Medina, R., Aguayo-Orozco, Alejandro, Johansen, J., Nissen, Jakob Nybo, Brorsson, Caroline, Mazzoni, Gianluca, Niu, L., Biel, J., Brasas, Valentas, Webel, Henry, Benros, M., Pedersen, A., Chmura, Piotr Jaroslaw, Jacobsen, U., Mari, Andrea, Koivula, R., Mahajan, Anubha, Vinuela, A., Tajes, Juan Fernandez, Sharma, Sapna, Haid, M., Hong, M., Musholt, Petra B, De Masi, Federico, Vogt, Josef, Pedersen, Helle Krogh, Gudmundsdottir, Valborg, Jones, Angus, Kennedy, G., Bell, Jimmy, Thomas, E.L., Frost, G., Thomsen, Henrik, Hansen, Elizaveta, Hansen, T., Vestergaard, Henrik, Muilwijk, Mirthe, Blom, Marieke T, 't Hart, Leen M, Pattou, Francois, Raverdy, Violeta, Brage, Soren, Kokkola, Tarja, Heggie, Alison, McEvoy, Donna, Mourby, Miranda, Kaye, J., Hattersley, A., McDonald, Timothy, Ridderstråle, M., Walker, Mark, Forgie, Ian, Giordano, Giuseppe N, Pavo, Imre, Ruetten, Hartmut, Pedersen, O., Hansen, T., Dermitzakis, Emmanouil, Franks, Paul W, Schwenk, J., Adamski, Jerzy, McCarthy, Mark I, Pearson, Ewan, Banasik, Karina, Rasmussen, S., Brunak, S. and IMI DIRECT Consortium 2023. Discovery of drug-omics associations in type 2 diabetes with generative deep-learning models. Nature Biotechnology. 41, pp. 399-408. https://doi.org/10.1038/s41587-022-01520-x

Thanaj, M., Basty, N., Cule, M., Sorokin, E.P., Whitcher, B., Bell, J.D. and Thomas, E.L. 2023. Preprint: Liver Shape Analysis using Statistical Parametric Maps at Population Scale. medRxiv. https://doi.org/10.1101/2022.08.18.22278951

Nunn, A., Guy, G.W., Brysch, W and Bell, J.D. 2022. Understanding Long COVID; Mitochondrial Health and Adaptation—Old Pathways, New Problems. Biomedicines. 10 (12) 3113. https://doi.org//10.3390/biomedicines10123113

Ichim, M. C., Scotti, F. and Booker, A. 2022. Quality evaluation of commercial herbal products using chemical methods. Critical Reviews in Food Science and Nutrition. Advanced online publication. https://doi.org/10.1080/10408398.2022.2140120

Mould, R., Thomas, E.L., Guy, G., Nunn, A. and Bell, J.D. 2022. Cell-Cell Death Communication by Signals Passing Through Non-Aqueous Environments: A Reply . Results in Chemistry. 4 100538. https://doi.org/10.1016/j.rechem.2022.100538

O’Donovan, S.D., Erdős, B., Jacobs, D.M., Wanders, A.J., Thomas, E.L., Bell, J.D., Rundle, M., Frost, G., Arts, I.C.W., Afman, L.A. and van Riel, A.A.W. 2022. The Mixed Meal Model: quantifying the contribution of 1 triglycerides to metabolic resilience. iScience. 25 (11) 105206. https://doi.org/10.1016/j.isci.2022.105206

Asaturyan, A.H., Basty, N., Thanaj, M., Whitcher, B., Thomas, E.L. and Bell, J.D. 2022. Improving the accuracy of fatty liver index to reflect liver fat content with predictive regression modelling. PLoS ONE. 17 (9) e0273171. https://doi.org/10.1371/journal.pone.0273171

Nunn, A.V.W., Guy, G.W. and Bell, J.D. 2022. Bioelectric Fields at the Beginnings of Life. Bioelectriciy. 4 (4), pp. 237-247. https://doi.org/10.1089/bioe.2022.0012

Booker, A., Heinrich, P.M. and Tsou, W.H. 2022. Chinese and Western Herbal Medicines for the Topical Treatment of Psoriasis - a critical review of Efficacy and Safety. Journal of Herbal Medicine. 34. https://doi.org/10.1016/j.hermed.2022.100579

Fiamoncini, J, Donado-Pestana, C.M., Duarte, G.B.S., Rundle, M, Thomas, E.L., Kiselova-Kaneva, Y., Gundersen, T.E., Bunzel, D., Trezzi, J.P., Kulling, S.E., Hiller, K., Sonntag, D., Ivanova, D., Brennan, L., Wopereis, S., van Ommen, B., Frost, G., Bell, J.D., Drevon, C.A. and Daniel, H. 2022. Plasma metabolic signatures of healthy overweight subjects challenged with an oral glucose tolerance test. Frontiers in Nutrition: Nutrition and Metabolism. https://doi.org/10.3389/fnut.2022.898782

Gu, J., Scotti, F., Reich, E., Kirchhoff, R., Booker, A. and Heinrich, P.M. 2022. Chrysanthemum species used as food and medicine: Understanding quality differences on the global market. South African Journal of Botany. 148, pp. 123-134. https://doi.org/10.1016/j.sajb.2022.04.009

Sorokin, E., Basty, N., Whitcher, B., Liu, Y., Bell, J.D., Cohen, R.L., Cule, M. and Thomas, E.L. 2022. Analysis of MRI-derived spleen iron in the UK Biobank identifies genetic variation linked to iron homeostasis and hemolysis. American Journal of Human Genetics. 109 (6), pp. P1092-1104. https://doi.org/10.1016/j.ajhg.2022.04.013

Sheridan, D.A., Shawa, I.T., Thomas, E.L., Felmlee, D.J., Bridge, S.H., Neely, D., Cobbold, J.F., Holmes, E., Bassendine, M.F. and Taylor-Robinson, S.D. 2022. Infection with the hepatitis C virus causes viral genotype-specific differences in cholesterol metabolism and hepatic steatosis. Scientific Reports. 12 5562. https://doi.org/10.1038/s41598-022-09588-w

Osimo, E., Brugger, S., Thomas, E.L. and Howes, O. 2022. A cross-sectional MR study of body fat volumes and distribution in chronic schizophrenia. Schizophrenia. 8 24. https://doi.org/10.1038/s41537-022-00233-z

Whitcher, B., Thanaj, M., Cule, M., Liu, Y., Basty, N., Sorokin, E., Bell, J.D. and Thomas, E.L. 2022. Precision MRI Phenotyping Enables Detection of Small Changes in Body Composition for Longitudinal Cohorts. Scientific Reports. 12 3748. https://doi.org/10.1038/s41598-022-07556-y

Nunn, A.V.W., Guy, G.W. and Bell, J.D. 2022. Thermodynamics and Inflammation: Insights into Quantum Biology and Ageing. Quantum Reports. 4, pp. 47-74. https://doi.org/10.3390/quantum4010005

Martin, S., Tyrrell, J., Thomas, E.L., Bown, M.J., Wood, A.R., Beaumont, R.N., Tsoi, L.C., Stuart, P.E., Elder, J.T., Law, P., Houlston, R., Kabrhel, C., Papadimitriou, N., Gunter, M.J., Bull, C.J., Bell, J.A., Vincent, E.E., Sattar, N., Dunlop, M.G., Tomlinson, I.P.M., Bell, J.D., Frayling, T. and Yaghootkar, H. 2022. Disease consequences of higher adiposity uncoupled from its adverse metabolic effects using Mendelian randomisation. eLife. 11 e72452. https://doi.org/10.7554/elife.72452

Wesolowska-Andersen, A., Brorsson, C.A., Bizzotto, R., Mari, A., Tura, A., Koivula, R., Mahajan, A., Viñuela, A., Fernandez Tajes, J, Sharma, S., Haid, M., Prehn, C., Artati, A., Hong, M-G, Musholt, P.B, Kurbasic, A., Masi, F., Tsirigos, K, Pedersen, H., Gudmundsdottir, V., Thomas, C., Banasik, K., Jennison, C., Jones, A., Kennedy, G., Bell, J.D., Thomas, E.L., Frost, G., Thomsen, H., Allin, K., Hansen, T.H., Vestergaard, H., Hansen, T., Rutters, F., Elders, P., t'Hart, L., Bonnefond, A., Canouil, M., Brage, S., Kokkola, T., Heggie, A., McEvoy, D., Hattersley, A., McDonald, T., Teare, H., Ridderstrale, M., Walker, M., Forgie, I., Giordano, G.N., Froguel, P., Pavo, I., Ruetten, H., Pedersen, O., Dermitzakis, E., Franks, P.W., Schwenk, J.M., Adamski, J., Pearson, E., McCarthy, M.I., Brunak, S. and IMI DIRECT Consortium 2022. Four groups of type 2 diabetes contribute to the etiological and clinical heterogeneity in newly diagnosed individuals: An IMI DIRECT study. Cell Reports Medicine. 3 (1) 100477. https://doi.org/10.1016/j.xcrm.2021.100477

Martin, Susan, Sorokin, Elena P, Thomas, E Louise, Sattar, Naveed, Cule, Madeleine, Bell, Jimmy D and Yaghootkar, H. 2022. Estimating the Effect of Liver and Pancreas Volume and Fat Content on Risk of Diabetes: A Mendelian Randomization Study. Diabetes Care. 45 (2), pp. 460-468. https://doi.org/10.2337/dc21-1262

Nunn, A., Guy, G., Botchway, S.W. and Bell, J.D. 2021. SARS-CoV-2 and EBV; the cost of a second mitochondrial "whammy"? Immunity & Ageing. 18 (1), pp. 40-44. https://doi.org/10.1186/s12979-021-00252-x

Osimo, E.F., Sweeney, M., de Marvao, A., Berry, A., Statton, B., Perry, B.I., Pillinger, T., Whitehurst, T., Cook, S.A., O’Regan, D.P., Thomas, E.L. and Howes, O.D. 2021. Adipose tissue dysfunction, inflammation, and insulin resistance alternative pathways to cardiac remodelling in schizophrenia. A multimodal, case-control study. Translational Psychiatry. 11 614. https://doi.org/10.1038/s41398-021-01741-9