Research Centre for Optimal Health

Thanaj, M., Basty, N., Cule, M., Sorokin, E.P., Whitcher, B., Bell, J.D. and Thomas, E.L. 2023. Preprint: Liver Shape Analysis using Statistical Parametric Maps at Population Scale. medRxiv. https://doi.org/10.1101/2022.08.18.22278951

Marjola Thanaj, Nicolas Basty, Brandon Whitcher, Elena P. Sorokin, Yi Liu, Ramprakash Srinivasan, Madeleine Cule, E. Louise Thomas and Jimmy D. Bell 2023. Preprint: Precision MRI phenotyping of muscle volume and quality at a population scale. medRxiv. https://doi.org/10.1101/2023.03.02.23286689

Bizzotto, R., Jennison, C., Jones, A., Kurbasic, A., Kennedy, G., Bell, J.D., Thomas, E.L., Frost, G., Eriksen, R., Koivula, R., Brage, S., Kaye, J., Hattersley, A., Heggie, A., McEvoy, D., Hart, L.M., Beulens, J.W., Elders, P., Musholt, P.B., Ridderstråle, M., Hansen, T., Allin, K., Hansen, T., Vestergaard, H., Lundgaard, A.T., Thomsen, H.S., Masi, F., Tsirigos, K.D., Brunak, S., Viñuela, A., Mahajan, A., McDonald, T.J., Kokkola, T., Forgie, I., Giordano, G.N., Pavo, I., Ruetten, H., Dermitzakis, E., McCarthy, M., Pedersen, O., Schwenk, J., Adamski, J., Franks, P., Walker, M., Pearson, E. and Mari, A. 2021. Processes Underlying Glycemic Deterioration in Type 2 Diabetes: An IMI DIRECT Study. Diabetes Care. 44 (2), pp. 511-518. https://doi.org/10.2337/dc20-1567

Fitzpatrick, J., Chambers, E.S., Parkinson, J.R.C., Frost, G., Bell, J.D. and Thomas, E.L. 2017. Psoas major cross-sectional area: A potential marker of cardiorespiratory fitness. International Journal of Clinical and Experimental Physiology. 4 (1), pp. 15-20. https://doi.org/10.4103/ijcep.ijcep_6_17

Agapouda, A., Booker, A., Kiss, T., Hohmann, J., Heinrich, M. and Csupor, D. 2019. Quality Control of Hypericum perforatum L. Analytical challenges and recent progress. Journal of Pharmacy and Pharmacology. 71 (1), pp. 15-37. https://doi.org/10.1111/jphp.12711

Ichim, M. C., Scotti, F. and Booker, A. 2022. Quality evaluation of commercial herbal products using chemical methods. Critical Reviews in Food Science and Nutrition. Advanced online publication. https://doi.org/10.1080/10408398.2022.2140120

O'Donovan, S., Rundle, M., Thomas, E.L., Bell, J.D., Frost, G., Jacobs, D.M., Wanders, A., de Vries, R., Mariman, E.C.M., va Baak, M.A., Sterkman, L., Nieuwdorp, M., Groem, A.K., Arts, I.C.W., van Riel, N. and Afman, L.A. 2024. Quantifying the effect of nutritional interventions on metabolic resilience using personalised computational models. iScience. 27 (4) 109362. https://doi.org/10.1016/j.isci.2024.109362

Mojtahed, A., Kelly, C.J., Herlihy, A.H., Kin, S., Wilman, H.R., McKay, A., Kelly, M., Milanesi, M., Neubauer, S,, Thomas, E.L., Bell, J.D., Banerjee, R. and Harisinghani, M. 2019. Reference range of liver corrected T1 values in a population at low risk for fatty liver disease-a UK Biobank sub-study, with an appendix of interesting cases. Abdominal Radiology. 44 (1), pp. 72-84. https://doi.org/10.1007/s00261-018-1701-2

Bachtiar, V., Kelly, M.D., Wilman, H.R., Jacob, J., Newbould, R., Kelly, C.J., Gyngell, M.L., Groves, K.E., McKay, A., Herlihy, A.H., Fernandes, C.C., Halberstadt, M., Maguire, M., Jayaratne, N., Linden, S., Neubauer, S. and Banerjee, R. 2019. Repeatability and reproducibility of multiparametric magnetic resonance imaging of the liver. PLoS ONE. 14 (4) e0214921. https://doi.org/10.1371/journal.pone.0214921

Cobbold, J.F.L., Atkinson, S., Marchesi, J.R., Smith, A., Wai, S.N., Stove, J., Shojaee-Moradie, F., Jackson, N.C., Umpleby, A.M., Fitzpatrick, J., Thomas, E.L., Bell, J.D., Holmes, E., Taylor-Robinson, S.D., Goldin, R.D., Yee, M.S., Anstee, Q.M. and Thursz, M.R. 2018. Rifaximin in Non-Alcoholic Steatohepatitis: An Open-Label Pilot Study. Hepatology Research. 48 (1), pp. 69-77. https://doi.org/10.1111/hepr.12904

Mackenzie, A.M., Smith, H.E., Mould, R., Bell, J.D., Nunn, A. and Botchway, S.W. 2024. Rooting out ultraweak photon emission a-mung bean sprouts. Journal of Photochemistry and Photobiology. 19 100224. https://doi.org/10.1016/j.jpap.2023.100224

Nunn, A., Guy, G., Botchway, S.W. and Bell, J.D. 2021. SARS-CoV-2 and EBV; the cost of a second mitochondrial "whammy"? Immunity & Ageing. 18 (1), pp. 40-44. https://doi.org/10.1186/s12979-021-00252-x

Nunn, A.V.W., Guy, G.W., Brysch, W., Botchway, S.W., Frasch, W., Calabrese, E.J. and Bell, J.D. 2020. SARS-CoV-2 and mitochondrial health: implications of lifestyle and ageing. Immunity & Ageing. 17 33 (2020). https://doi.org/10.1186/s12979-020-00204-x

Dikariyanto, V., Smith, L., Francis, L., Robertson, M., Kusaslan, E., O’Callaghan-Latham, M., Palanche, C., D’Annibale, M., Christodoulou, D., Basty, N., Whitcher, B., Shuaib, H., Charles-Edwards, G., Chowienczyk, P.J., Ellis, P. R., Berry, S.E. and Hall, W. 2020. Snacking on whole almonds for 6 weeks improves endothelial function and lowers LDL cholesterol but does not affect liver fat and other cardiometabolic risk factors in healthy adults: the ATTIS study, a randomized controlled trial. American Journal of Clinical Nutrition. 111 (6), p. 1178–1189. https://doi.org/10.1093/ajcn/nqaa100

Mole, D.J., Fallowfield, J.A., Kendall, T.J., Welsh, F., Semple, S.I., Bachtiar, V., Kelly, M., Wigmore, S.J., Garden, O.J., Wilman, H.R., Banerjee, R., Rees, M. and Brady, M. 2018. Study protocol: HepaT1ca - an observational clinical cohort study to quantify liver health in surgical candidates for liver malignancies. BMC Cancer . 18, p. 890 890. https://doi.org/10.1186/s12885-018-4737-3.

Linge, J., Whitcher, B., Borga, M. and Dahlqvist Leinhard, O. 2019. Sub‐phenotyping Metabolic Disorders Using Body Composition: An Individualized, Nonparametric Approach Utilizing Large Data Sets. Obesity. 27 (7), pp. 1190-1199. https://doi.org/10.1002/oby.22510

Alzoubi, S., Brody, L., Rahman, S., Mahul-Mellier, A.L., Mercado, N., Ito, K., El-Bahrawy, M., Silver, A., Boobis, A., Bell, J.D. and Hajji, N. 2016. Synergy between histone deacetylase inhibitors and DNA- damaging agents is mediated by histone deacetylase 2 in colorectal cancer. Oncotarget . 7 (28), pp. 44505-44521. https://doi.org/10.18632/oncotarget.9887

Eriksen, Rebeca, White, Margaret C., Dawed, Adem Y., Perez, Isabel Garcia, Posma, Joram M., Haid, Mark, Sharma, Sapna, Prehn, Cornelia, Thomas, E. Louise, Koivula, Robert W., Bizzotto, Roberto, Mari, Andrea, Giordano, Giuseppe N., Pavo, Imre, Schwenk, Jochen M., De Masi, Federico, Tsirigos, Konstantinos D., Brunak, Søren, Viñuela, Ana, Mahajan, Anubha, McDonald, Timothy J., Kokkola, Tarja, Rutters, Femke, Beulens, Joline, Muilwijk, Mirthe, Blom, Marieke, Elders, Petra, Hansen, Tue H., Fernandez-Tajes, Juan, Jones, Angus, Jennison, Chris, Walker, Mark, McCarthy, Mark I., Pedersen, Oluf, Ruetten, Hartmut, Forgie, Ian, Holst, Jens J., Thomsen, Henrik S., Ridderstråle, Martin, Bell, Jimmy D., Adamski, Jerzy, Franks, Paul W., Hansen, Torben, Holmes, Elaine, Frost, Gary and Pearson, Ewan R. 2024. The Association of Cardiometabolic, Diet and Lifestyle Parameters With Plasma Glucagon-like Peptide-1: An IMI DIRECT Study. The Journal of Clinical Endocrinology & Metabolism. Advanced online publication. https://doi.org/10.1210/clinem/dgae119

Chambers, E.S., Byrne, C.S., Rugyendo, A., Morrison, D.J., Preston, T., Tedford, M.C., Bell, J.D., Thomas, E.L., Akbar, A.N., Riddell, N.E., Sharma, R., Thursz, M.R., Manousou, P. and Frost, G. 2019. The effects of dietary supplementation with inulin and inulin-propionate ester on hepatic steatosis in adults with non-alcoholic fatty liver disease. Diabetes, Obesity and Metabolism. 21 (2), pp. 372-376. https://doi.org/10.1111/dom.13500

Nunn, A.V.W., Guy, G.W. and Bell, J.D. 2017. The Hormesis of Thinking: A Deeper Quantum Thermodynamic Perspective? International Journal of Neurorehabilitation. 4 (3), p. 272 272. https://doi.org/10.4172/2376-0281.1000272

O’Donovan, S.D., Erdős, B., Jacobs, D.M., Wanders, A.J., Thomas, E.L., Bell, J.D., Rundle, M., Frost, G., Arts, I.C.W., Afman, L.A. and van Riel, A.A.W. 2022. The Mixed Meal Model: quantifying the contribution of 1 triglycerides to metabolic resilience. iScience. 25 (11) 105206. https://doi.org/10.1016/j.isci.2022.105206

Bell, J.D., Nunn, A.V.W. and Guy, G.W. 2016. The Quantum Mitochondrion and Optimal Health. Biochemical Society Transactions. 44 (4), pp. 1101-1110. https://doi.org/10.1042/BST20160096

Koivula, R.W., Atabaki-Pasdar, N, Giordano, G.N., White, T., Adamski, J., Bell, J.D., Beulens, J, Brage, S, Brunak, S., De Masi, F., Dermitzakis, E.T., Forgie, I.M., Frost, G.S., Hansen, T., Hansen, T.H., Hattersley, A., Kokkola, T., Kurbasic, A., Laakso, M., Mari, A., McDonald T.J., Pedersen, O., Rutters, F., Schwenk, J.M, Teare, H.J.A., Thomas, E.L., Vinuela, A., Mahajan, A., McCarthy, M.I., Ruetten, H., Walker, M., Pearson, E., Pavo, I. and Franks, P.W. 2020. The role of physical activity in metabolic homeostasis before and after the onset of type 2 diabetes: an IMI DIRECT study. Diabetologia. https://doi.org/10.1007/s00125-019-05083-6

Littlejohns, T., Holliday, J., Gibson, L., Garratt, S., Oesingmann, N., Alfaro-Almagro, F., Bell, J.D., Boultwood, C., Collins, R., Conroy, M., Crabtree, N., Doherty, N., Frangi, A., Harvey, N., Leeson, P., Miller, K., Neubauer, S., Petersen, S., Sellors, J., Sheard, S., Smith, S., Sudlow, C., Matthews, P. and Allen, N. 2020. The UK Biobank imaging enhancement of 100,000 participants: rationale, data collection, management and future directions. Nature Communications . 11 2624. https://doi.org/10.1038/s41467-020-15948-9

Smith, H.E., Mackenzie, A.M., Seddon, C., Mould, R., Kalampouka, I., Bateman, B., Needham, S.R., Beis, K., Bell, J.D., Nunn, A. and Botchway, S.W. 2024. The Use of NADH Anisotropy to Investigate Mitochondrial Cristae Alignment. Scientific Reports. 14 5980. https://doi.org/10.1038/s41598-024-55780-5

Cresswell, E., Basty, N., Atabaki-Pasdar, N., Karpe, F. and Pinnick, K.E. 2024. The value of neck adipose tissue as a predictor for metabolic risk in health and type 2 diabetes. Biochemical Pharmacology. Advanced online publication. https://doi.org/10.1016/j.bcp.2024.116171

Nunn, A.V.W., Guy, G.W. and Bell, J.D. 2022. Thermodynamics and Inflammation: Insights into Quantum Biology and Ageing. Quantum Reports. 4, pp. 47-74. https://doi.org/10.3390/quantum4010005

Hameed, S., Patterson, M., Dhillo, W.S., Rahman, S.A., Ma, Y., Holton, C., Gogakos, A., Yeo, G.S.H., Lam, B.Y.H., Polex-Wolf, J., Fenske, W., Bell, J.D., Anastasovska, J., Samarut, J., Bloom, S.R., Bassett, J.H.D., Williams, G.R. and Gardiner, J.V. 2017. Thyroid Hormone Receptor Beta in the Ventromedial Hypothalamus Is Essential for the Physiological Regulation of Food Intake and Body Weight. Cell Reports. 19 (11), pp. 2202-2219. https://doi.org/10.1016/j.celrep.2017.05.066

Booker, A., Scotti, F., Mou, L., Huang, C., Werckerle, C., Maake, C. and Heinrich, M. 2021. Treating Chronic Wounds Using Photoactive Metabolites: Data Mining the Chinese Pharmacopoeia for Potential Lead Species. Planta Medica. 87, pp. 1-13. https://doi.org/10.1055/a-1578-8778

Chatzinasiou, L., Booker, A., MacLennan, E., Mackonochie, M. and Heinrich, M. 2019. Turmeric (Curcuma longa L.) products: What quality differences exist? Journal of Herbal Medicine. 17-18, p. 100281 100281. https://doi.org/10.1016/j.hermed.2019.100281

Mould, R., Mackenzie, A.M., Kalampouka, I., Nunn, A., Thomas, E.L., Bell, J.D. and Botchway, S.W. 2024. Ultra Weak Photon Emission - A Brief Review. Frontiers in Physiology - Biophysics. 15 1348915. https://doi.org/10.3389/fphys.2024.1348915

Booker, A., Heinrich, M., Scotti, F., Fitzgerald, M., Kum, K.Y. and Lobel, K. 2019. Unblocking high-value botanical value chains: Is there a role for blockchain systems? Frontiers in Pharmacology. 10 396. https://doi.org/10.3389/fphar.2019.00396

Nunn, A., Guy, G.W., Brysch, W and Bell, J.D. 2022. Understanding Long COVID; Mitochondrial Health and Adaptation—Old Pathways, New Problems. Biomedicines. 10 (12) 3113. https://doi.org//10.3390/biomedicines10123113