Gyamfi-Brobbey, George, Greenwell, P. and Kimmitt, P.T. 2015. In Vitro Assessment of the Synergy between Polymyxin B (PMB) and Polymyxin B Nonapeptide (PMBN) and Antibiotics on Biofilms from Diabetic Foot Infections. American Society for Microbiology. New Orleans 31 May 2015
| Title | In Vitro Assessment of the Synergy between Polymyxin B (PMB) and Polymyxin B Nonapeptide (PMBN) and Antibiotics on Biofilms from Diabetic Foot Infections |
|---|---|
| Authors | Gyamfi-Brobbey, George, Greenwell, P. and Kimmitt, P.T. |
| Type | Conference poster |
| Abstract | Background: The increasing resistance of Gram-negative bacteria isolated from nosocomial infections and chronic wounds, such as diabetic foot ulcers has renewed research interests in the use of polymyxins in the treatment of multidrug resistant infections. The added resistance conferred by biofilm development in such infections and the absence of novel antibiotics presuppose that polymyxins are the likely drugs of choice in spite of their nephrotoxicity. The effects of PMB and PMBN have been previously assessed on planktonic bacteria isolated from various infections. Methods: This current study assessed the synergy between a PMB/PMBN and two antibiotics (ceftazidime and levofloxacin) in an attempt to develop a strategy for biofilm disruption using the Minimum Biofilm Eradication Concentration Physiology and Genetic assay (MBEC™ P & G, Innovotech Inc, Edmonton, Alberta, Canada) according to manufacturer’s instructions. Klebsiella pneumoniae (K. pneumoniae) and Proteus mirabilis (P. mirabilis) biofilms of initial broth suspensions of 108 colony forming units per mL, cultivated on the pegs of the MBEC device were challenged with 5120 µg/mL of both ceftazidime and levofloxacin in a ten-fold dilution assay and in the presence of 100 and 500 µg/mL PMB and PMBN. Results: From table of results (Table 1), it can be deduced that both ceftazidime and levofloxacin are very effective in inhibiting biofilm development (as shown by percentage inhibition (PI)) when augmented with PMB and PMBN. This is about 100-fold increase in efficacy when compared to the antibiotics used on their own. The percentage reduction (PR) in biofilm was also increased considerably when PMB and PMBN concentrations were increased to 500 µg/mL. PMB was more effective than its less antibacterial derivative PMBN. Levofloxacin was also found to be more effective than ceftazidime when combined with both PMB and PMBN due to its enhanced cell-membrane permeability and as an anti-DNA replication uncoupling agent. Conclusion: The above results indicate that the synergy between antibiotics and cell membrane permeabilising agents may provide alternate strategies towards biofilm eradication |
| Year | 2015 |
| Conference | American Society for Microbiology |
| Accepted author manuscript |
Human papilloma virus genotype distribution and risk factor analysis amongst reproductive aged women in urban Gambia
Bah Camara, H., Anyanwu, M., Wright, E. and Kimmitt, P.T. 2018. Human papilloma virus genotype distribution and risk factor analysis amongst reproductive aged women in urban Gambia. Journal of Medical Microbiology. 67, pp. 1645-1654. https://doi.org/10.1099/jmm.0.000848
Human Papillomavirus Sero-prevalence and Sexual Attitudes Amongst a Cohort of HIV Positive Women In The Gambia
Bah Camara, H., Anyanwu, M., Drammeh, J., Njie, A., Mattiuzzo, G., Gillard, L., Wright, E. and Kimmitt, P.T. 2018. Human Papillomavirus Sero-prevalence and Sexual Attitudes Amongst a Cohort of HIV Positive Women In The Gambia. ASM Microbe. Atlanta, Georgia 07 - 11 Jun 2018
Sexually Transmitted Diseases: Time to Revisit the Syndromic Management Approach
Bah Camara, H., Noho, A., Sanyang, A., Wright, E. and Kimmitt, P.T. 2018. Sexually Transmitted Diseases: Time to Revisit the Syndromic Management Approach. ASM Microbe. Atlanta, Georgia 07 - 11 Jun 2018
Efficacy Of The Quadrivalent HPV Vaccine In Cervical Cancer Prevention Strategy In The Gambia
Bah Camara, H., Anyanwu, M., Banja, F., Mboob-Suun, K., Ceesay, F., Wright, E. and Kimmitt, P.T. 2017. Efficacy Of The Quadrivalent HPV Vaccine In Cervical Cancer Prevention Strategy In The Gambia. EUROGIN17. Amsterdam 08 - 11 Oct 2017
Gamification in Higher Education: Students and Academics Interest in Gaming
Kimmitt, P.T. 2017. Gamification in Higher Education: Students and Academics Interest in Gaming. 9th Annual International Conference on Education and New Learning Technologies. Barcelona, Spain 03 - 05 Jul 2017 IATED Academy. https://doi.org/10.21125/edulearn.2017.2258
A Preliminary Report: Cervical Human Papilloma Virus Genotype Distribution in Reproductive Aged Women Attending Primary Health Care in Urban Gambia
Bah Camara, H., Mboob -Suun, K., Banja, F., Ceesay, F., Anyanwu, M., Wright, E. and Kimmitt, P.T. 2017. A Preliminary Report: Cervical Human Papilloma Virus Genotype Distribution in Reproductive Aged Women Attending Primary Health Care in Urban Gambia. Microbiology Society Annual Conference 2017. Edinburgh 03 - 06 Apr 2017
Prevalance of Ureaplasma parvum and urealyticum in Urban Gambian Women
Bah Camara, H., Noho, A., Sanyang, A., Barrow, E., Wright, E. and Kimmitt, P.T. 2017. Prevalance of Ureaplasma parvum and urealyticum in Urban Gambian Women. Microbiology Society Annual Conference 2017. Edinburgh 03 - 06 Apr 2017
The microbiology of diabetic foot infections: a Ghanaian perspective
Gyamfi-Brobbey, George 2016. The microbiology of diabetic foot infections: a Ghanaian perspective. PhD thesis University of Westminster Biomedical Sciences https://doi.org/10.34737/9yz27
Evaluation of the potential for virus dispersal during hand drying: a comparison of three methods
Kimmitt, P.T. and Redway, K. 2016. Evaluation of the potential for virus dispersal during hand drying: a comparison of three methods. Journal of Applied Microbiology. 120 (2), pp. 478-486. https://doi.org/10.1111/jam.13014
Characterisation of hepcidin response to holotransferrin treatment in CHO TRVb-1 cells
Mehta, K., Greenwell, P., Renshaw, D., Busbridge, Mark, Garcia, M, Farnaud, S. and Patel, V. B. 2015. Characterisation of hepcidin response to holotransferrin treatment in CHO TRVb-1 cells. Blood Cells, Molecules, and Diseases. 55 (2), pp. 110-118. https://doi.org/10.1016/j.bcmd.2015.05.002
Application of RT-Bst to enhance detection of pathogenic viruses of the respiratory tract
Kabir, M.S., Clements, M.O., Atkins, M. and Kimmitt, P.T. 2015. Application of RT-Bst to enhance detection of pathogenic viruses of the respiratory tract. British Journal of Biomedical Science. 72 (3), pp. 128-134.
Comparison of virus dispersal and aerosolization by different hand-drying devices
Kimmitt, P.T. and Redway, K. 2015. Comparison of virus dispersal and aerosolization by different hand-drying devices. European Public Health Conference. Milan 14 Oct 2015
The risk of viral dispersal and aerosolization by different hand-drying methods
Redway, K. and Kimmitt, P.T. 2015. The risk of viral dispersal and aerosolization by different hand-drying methods. 3rd International Conference on Prevention and Infection Control (ICPIC). Geneva 16 Jun 2015
F. necrophorum Ecotin Inhibits Human Plasma Kallikrein and Human Neutrophil Elastase
Wright Katie Greenwell Pamela, Greenwell, P. and Kimmitt, P.T. 2015. F. necrophorum Ecotin Inhibits Human Plasma Kallikrein and Human Neutrophil Elastase. American Society for Microbiology. New Orleans 31 May 2015
A quantitative evaluation of three hand drying methods and the potential for dissemination of virus particles into the environment
Kimmitt, P.T. and Redway, K. 2015. A quantitative evaluation of three hand drying methods and the potential for dissemination of virus particles into the environment. Society for General Microbiology. Birmingham 01 Apr 2015
Presence and characterisation of ecotin in F. necrophorum
Wright Katie Greenwell Pamela, Kimmitt, P.T. and Greenwell, P. 2015. Presence and characterisation of ecotin in F. necrophorum. Society for General Microbiology. Birmingham 30 Mar 2015
Comparison of virulence genes found in draft genomes of F. necrophorum
Wright Katie Greenwell Pamela, Kimmitt, P.T. and Greenwell, P. 2015. Comparison of virulence genes found in draft genomes of F. necrophorum. Society for General Microbiology. Birmingham, UK 30 Mar 2015
In vitro study of the effect of wound dressings on planktonic and biofilms from diabetic foot isolates
Omobolanle, Omotosho, Gyamfi-Brobbey, George, Kimmitt, P.T. and Greenwell, P. 2015. In vitro study of the effect of wound dressings on planktonic and biofilms from diabetic foot isolates. Society for General Microbiology. Birmingham 30 Mar 2015
Cinnamaldehyde increases the susceptibility of quorum-sensing-mediated biofilms to conventional antibiotics
Gyamfi-Brobbey, George, Kimmitt, P.T. and Greenwell, P. 2015. Cinnamaldehyde increases the susceptibility of quorum-sensing-mediated biofilms to conventional antibiotics. Society for General Microbiology. Birmingham 30 Mar 2015
The in vitro assessment of the synergistic effects of antibiotics and wound dressings on biofilms from diabetic foot pathogens
Gyamfi-Brobbey, George, Kimmitt, P.T. and Greenwell, P. 2015. The in vitro assessment of the synergistic effects of antibiotics and wound dressings on biofilms from diabetic foot pathogens. Society for General Microbiology. Birmingham 30 Mar 2015
RT-Bst: an integrated approach for reverse transcription and enrichment of cDNA from viral RNA
Kabir, Md. Shahidul, Kimmitt, P.T. and Clements, M.O. 2015. RT-Bst: an integrated approach for reverse transcription and enrichment of cDNA from viral RNA. British Journal of Biomedical Sciences. 72 (1), pp. 1-6.
Hand drying method and risk of microbe dissemination: methods and benchmarks
Redway, K. and Kimmitt, P.T. 2014. Hand drying method and risk of microbe dissemination: methods and benchmarks. Hospital Infection Society. Lyon, France 18 Nov 2014
Differing methodologies to measure microbe dispersal during hand drying
Redway, K. and Kimmitt, P.T. 2014. Differing methodologies to measure microbe dispersal during hand drying. Hospital Infection Society. Lyon, France 17 Nov 2014
Buttressing volatile desktop grids with cloud resources within a reconfigurable environment service for workflow orchestration
Winter, S., Reynolds, C.J., Kiss, T., Terstyanszky, G., Greenwell, P., McEldowney, S., Acs, S. and Kacsuk, P. 2014. Buttressing volatile desktop grids with cloud resources within a reconfigurable environment service for workflow orchestration. Journal of Cloud Computing: Advances, Systems and Applications. 3 (1), p. 1. https://doi.org/10.1186/2192-113X-3-1
Large-scale virtual screening experiments on Windows Azure-based cloud resources
Kiss, T., Borsody, P., Terstyanszky, G., Winter, S., Greenwell, P., McEldowney, S. and Heindl, H. 2014. Large-scale virtual screening experiments on Windows Azure-based cloud resources. Concurrency and Computation: Practice and Experience. 26 (10), pp. 1760-1770. https://doi.org/10.1002/cpe.3113
The N-glycans of Trichomonas vaginalis contain variable core and antennal modifications
Paschinger, K., Hykollari, A., Razzazi-Fazeli, E., Greenwell, P., Leitsch, D., Walochnik, J. and Wilson, I.B.H. 2012. The N-glycans of Trichomonas vaginalis contain variable core and antennal modifications. Glycobiology. 22 (2), pp. 300-313. https://doi.org/10.1093/glycob/cwr149
Application repository and science gateway for running molecular docking and dynamics simulations
Terstyanszky, G., Kiss, T., Kukla, T., Lichtenberger, Z., Winter, S., Greenwell, P., McEldowney, S. and Heindl, H. 2012. Application repository and science gateway for running molecular docking and dynamics simulations. in: Gesing, S., Glatard, T., Kruger, J., Delgado Olabarriaga, S., Solomonides, T., Silverstein, J.C., Montagnat, J., Gaignard, A. and Krefting, D. (ed.) Healthgrid applications and technologies meet science gateways for life sciences IOS Press.
The lectin Helix pomatia agglutinin recognises O-GlcNAc containing glycoproteins in human breast cancer
Rambaruth, N.D.S., Greenwell, P. and Dwek, M. 2012. The lectin Helix pomatia agglutinin recognises O-GlcNAc containing glycoproteins in human breast cancer. Glycobiology. 22 (6), pp. 839-848. https://doi.org/10.1093/glycob/cws051
siRNA-mediated inhibition of Na^sup +^ -K^sup +^-2Cl^sup -^ cotransporter (NKCC1) and regulatory volume increase in the chondrocyte cell line C-20/A4
Qusous, A., Geewan, C., Greenwell, P. and Kerrigan, M.J.P. 2011. siRNA-mediated inhibition of Na^sup +^ -K^sup +^-2Cl^sup -^ cotransporter (NKCC1) and regulatory volume increase in the chondrocyte cell line C-20/A4. Journal of Membrane Biology. 243 (1-3), pp. 25-34. https://doi.org/10.1007/s00232-011-9389-z
Cation-π interactions induce kinking of a molecular hinge in the RNA polymerase bridge-helix domain
Heindl, H., Greenwell, P., Weingarten, N., Kiss, T., Terstyanszky, G. and Weinzierl, R.O.J. 2011. Cation-π interactions induce kinking of a molecular hinge in the RNA polymerase bridge-helix domain. Biochemical Society Transactions. 39 (1), pp. 31-35. https://doi.org/10.1042/BST0390031
Scientific workflow makespan reduction through cloud augmented desktop grids
Reynolds, C.J., Winter, S., Terstyanszky, G., Kiss, T., Greenwell, P., Acs, S. and Kacsuk, P. 2011. Scientific workflow makespan reduction through cloud augmented desktop grids. in: 2011 IEEE 3rd International Conference on Cloud Computing Technology and Science IEEE . pp. 18-23
Development of user-friendly, high throughput screening for ligands and inhibitors of carbohydrate modifying enzymes
Heindl, H., Greenwell, P., Kiss, T., Reynolds, C.J., Farkas, D., Terstyanszky, G. and Winter, S. 2011. Development of user-friendly, high throughput screening for ligands and inhibitors of carbohydrate modifying enzymes. 2nd glyco-bioinformatics Beilstein-Institut symposium. Potsdam, Germany 27th June – 1st July 2011
Pilot study of the utility and acceptability of tampon sampling for the diagnosis of Neisseria gonorrhoeae and Chlamydia trachomatis infections by duplex realtime polymerase chain reaction in United Kingdom sex workers
Kimmitt, P.T., Tabrizi, S.N., Crosatti, M., Garland, S.M., Schober, P.C., Rajakumar, Kumar and Chapman, Cordelia A. 2010. Pilot study of the utility and acceptability of tampon sampling for the diagnosis of Neisseria gonorrhoeae and Chlamydia trachomatis infections by duplex realtime polymerase chain reaction in United Kingdom sex workers. International Journal of STD & AIDS. 21 (4), pp. 279-282. https://doi.org/10.1258/ijsa.2009.009277
A two-tube combined TaqMan/SYBR green assay to identify Mycob acteria and detect single global lineage-defining polymorphisms in Mycobacterium tuberculosis
Cheah, E.S.G., Malkin, J., Free, R.C., Lee, S.M., Perera, N., Woltmann, G., Patel, H., Kimmitt, P.T., Smith, R.J., Rajakumar, Kumar and Barer, M.R. 2010. A two-tube combined TaqMan/SYBR green assay to identify Mycob acteria and detect single global lineage-defining polymorphisms in Mycobacterium tuberculosis. Journal of Molecular Diagnostics. 12 (2), pp. 250-256. https://doi.org/10.2353/jmoldx.2010.090030
Breast cancer invasion is mediated by beta-N-acetylglucosaminidase (beta-NAG) and associated with a dysregulation in the secretory pathway of cancer cells
Ramessur, K.T., Greenwell, P., Nash, R. and Dwek, M. 2010. Breast cancer invasion is mediated by beta-N-acetylglucosaminidase (beta-NAG) and associated with a dysregulation in the secretory pathway of cancer cells. British Journal of Biomedical Science. 67 (4), pp. 189-196.
Molecular docking simulations on a combined desktop and service grid infrastructure
Kiss, T., Szmetanko, G., Terstyanszky, G., Greenwell, P. and Heindl, H. 2010. Molecular docking simulations on a combined desktop and service grid infrastructure. in: Proceedings: Third AlmereGrid Desktop Experience workshop: desktop grid applications for eScience and eBusiness, 30 March 2010, Almere, The Netherlands EnterTheGrid. pp. 23-27
Parameter sweep workflows for modelling carbohydrate recognition
Kiss, T., Greenwell, P., Heindl, H., Terstyanszky, G. and Weingarten, N. 2010. Parameter sweep workflows for modelling carbohydrate recognition. Journal of Grid Computing. 8 (4), pp. 587-601. https://doi.org/10.1007/s10723-010-9166-8
ProSim: development of a user-friendly molecular modelling package
Heindl, H., Kiss, T., Terstyanszky, G., Weingarten, N., Afrough, B. and Greenwell, P. 2010. ProSim: development of a user-friendly molecular modelling package. in: Hicks, M.G. and Kettner, C. (ed.) Proceedings of the International Beilstein Symposium on Glyco-Bioinformatics: Bits ‘n’ Bytes of Sugars, October 4th – 8th, 2009, Potsdam, Germany Beilstein-Institut zur Fo¨rderung der Chemischen Wissenschaften. pp. 61-85
Cytoplasmic hybrid clones (cybrids) for stem cell production: ground-breaking research or a technology too far?
Greenwell, P. 2010. Cytoplasmic hybrid clones (cybrids) for stem cell production: ground-breaking research or a technology too far? Law, Science and Policy. 3, pp. 287-308.
Expression of the c-myc oncogene and the presence of HPV 18: possible surrogate markers for cervical cancer?
Rughooputh, S., Manraj, S., Eddoo, R. and Greenwell, P. 2009. Expression of the c-myc oncogene and the presence of HPV 18: possible surrogate markers for cervical cancer? British Journal of Biomedical Science. 66 (2), pp. 74-78.
ABO reverse grouping: effect of varying concentrations of the enzyme bromelain
Rookard, L.E., Edmondson, O. and Greenwell, P. 2009. ABO reverse grouping: effect of varying concentrations of the enzyme bromelain. British Journal of Biomedical Science. 66 (2), pp. 93-97.
Identification of Streptococcus gallolyticus subsp. macedonicus as the etiological agent in a case of culture-negative multivalve infective endocarditis by 16S rDNA PCR analysis of resected valvular tissue
Malkin, J., Ou, Hong-Yu, Khare Milind, Deng, Zixin, Stephenson, Iain, Perera, N., Rajakumar, Kumar, Kimmitt, P.T., Bhasker, Pretti S. Santi and Sosnowski, Andrew W. 2008. Identification of Streptococcus gallolyticus subsp. macedonicus as the etiological agent in a case of culture-negative multivalve infective endocarditis by 16S rDNA PCR analysis of resected valvular tissue. Journal of Heart Valve Disease. 17 (5), pp. 589-592.
Identification of Neisseria gonorrhoeae as the causative agent in a case of culture-negative dermatitis-arthritis syndrome using real-time PCR
Kimmitt, P.T., Kirby Andrew, Perera, N., Schober, Paul C., Rajakumar, Kumar, Chapman, Cordelia A. and Nicholson, Karl G. 2008. Identification of Neisseria gonorrhoeae as the causative agent in a case of culture-negative dermatitis-arthritis syndrome using real-time PCR. Journal of Travel Medicine. 15 (5), pp. 369-371. https://doi.org/10.1111/j.1708-8305.2008.00240.x
Purification and analysis of DNases of Tritrichomonas foetus: evidence that these enzymes are glycoproteins
Greenwell, P., Younes, M. and Rughooputh, S. 2008. Purification and analysis of DNases of Tritrichomonas foetus: evidence that these enzymes are glycoproteins. International Journal for Parasitology. 38 (7), pp. 749-756. https://doi.org/10.1016/j.ijpara.2007.10.012
Chikungunya virus: an emerging problem?
Rughooputh, S. and Greenwell, P. 2007. Chikungunya virus: an emerging problem? Biomedical Scientist.
Prevalence of human papillomavirus amongst cervical cancer sufferers amongst slum dwellers in India
Rughooputh, S., Kachaliya, S., Jetly, D. and Greenwell, P. 2007. Prevalence of human papillomavirus amongst cervical cancer sufferers amongst slum dwellers in India. British Journal of Biomedical Science. 64 (1), pp. 28-31.
Cervical cancer and human papillomavirus among slum dwellers in India
Rughooputh, S., Kachaliya, S., Jetly, D. and Greenwell, P. 2007. Cervical cancer and human papillomavirus among slum dwellers in India. British Journal of Biomedical Science. 64 (1), pp. 28-31.
Proteome analysis of metastatic colorectal cancer cells recognized by the lectin Helix pomatia agglutinin (HPA)
Saint-Guirons, J., Zeqiraj, E., Schumacher, U., Greenwell, P. and Dwek, M. 2007. Proteome analysis of metastatic colorectal cancer cells recognized by the lectin Helix pomatia agglutinin (HPA). Proteomics. 7 (22), pp. 4082-4089. https://doi.org/10.1002/pmic.200700434
Detection of human papillomavirus from archival tissues in cervical cancer patients in Mauritius
Rughooputh, S., Eddoo, R., Manraj, S., Jeebun, N. and Greenwell, P. 2006. Detection of human papillomavirus from archival tissues in cervical cancer patients in Mauritius. Journal of Clinical Virology. 35 (2), pp. 173-178. https://doi.org/10.1016/j.jcv.2005.03.010
A consensus on fungal polymerase chain reaction diagnosis?: A United Kingdom-Ireland evaluation of polymerase chain reaction methods for detection of systemic fungal infections
White, P.L., Barton, R., Guiver, M., Linton, C.J., Wilson, S., Smith, M., Gomez, B.L., Carr, M.J., Kimmitt, P.T., Seaton, S., Rajakumar, Kumar, Holyoake, T., Kibbler, C.C., Johnson, E., Hobson, R.P., Jones, B. and Barnes, R.A. 2006. A consensus on fungal polymerase chain reaction diagnosis?: A United Kingdom-Ireland evaluation of polymerase chain reaction methods for detection of systemic fungal infections. Journal of Molecular Diagnostics. 8 (3), pp. 376-384.
A proteomic approach to identify the integrins α 6 and α V as HPA binding partners in the metastatic colorectal cancer cell line HT29
Saint-Guirons, J., Zeqiraj, E., Greenwell, P. and Dwek, M. 2006. A proteomic approach to identify the integrins α 6 and α V as HPA binding partners in the metastatic colorectal cancer cell line HT29. Molecular and Cellular Proteomics. 5 (10 (supplement)), p. S148.
Association between HPV and C-MYC gene expression in cervical cancer
Rughooputh, S., Eddoo, R., Manraj, S., Jeebun, N. and Greenwell, P. 2006. Association between HPV and C-MYC gene expression in cervical cancer. International Journal of Molecular Medicine. 18 (supplement).
Analysis of glycosidases activity in Chlamydia trachomatis L2 serotype
Greenwell, P., Kakourou, G. and Rughooputh, S. 2006. Analysis of glycosidases activity in Chlamydia trachomatis L2 serotype. Internet Journal of Medical Update. 1 (1).
Vaccination against cervical cancer
Greenwell, P. and Rughooputh, S. 2005. Vaccination against cervical cancer. Biomedical Scientist. 49 (6), p. 441.
Proteomics: more than just biochemistry
Greenwell, P. and Rughooputh, S. 2005. Proteomics: more than just biochemistry. Biomedical Scientist. 49 (6), pp. 459-460.
Trichomonas vaginalis: paradigm of a successful sexually transmitted organism
Rughooputh, S. and Greenwell, P. 2005. Trichomonas vaginalis: paradigm of a successful sexually transmitted organism. British Journal of Biomedical Science. 62 (4), pp. 193-200.
Application of recombinant phage display antibody system in study of Codakia orbicularis gill proteins
Gourdine, J.P., Greenwell, P. and Smith-Ravin, E.J. 2005. Application of recombinant phage display antibody system in study of Codakia orbicularis gill proteins. Applied Biochemistry and Biotechnology. 125 (1), pp. 41-52.
The Unani system of medicine: does it have a scientific basis?
Syeda, A., Rughooputh, S. and Greenwell, P. 2004. The Unani system of medicine: does it have a scientific basis? Biomedical Scientist. 48 (9), pp. 971-972.
Genetically modified food: good news but bad press
Greenwell, P. and Rughooputh, S. 2004. Genetically modified food: good news but bad press. Biomedical Scientist. 48 (8), pp. 845-846.
Bioinformatics: a useful tool for the molecular microbiologist?
Greenwell, P. and Rughooputh, S. 2004. Bioinformatics: a useful tool for the molecular microbiologist? Biomedical Scientist. 48 (5), pp. 494-495.
Detection of human papillomavirus from liquid-based cytology specimens by in-house PCR: a pilot study
Rughooputh, S., Parmar, K. and Greenwell, P. 2004. Detection of human papillomavirus from liquid-based cytology specimens by in-house PCR: a pilot study. British Journal of Biomedical Science. 61 (1), pp. 22-25.
Use of bioinformatics and PCR in the search for ABC transporter homology among various bacteria
Jauhangeer, B.R., Wren, M.W.D., MacDonald, R.A.C., Perry, D. and Greenwell, P. 2004. Use of bioinformatics and PCR in the search for ABC transporter homology among various bacteria. British Journal of Biomedical Science. 61 (4), pp. 182-185.
Trichomonas vaginalis: an irritating protozoan or an important viral co-factor
Greenwell, P. and Rughooputh, S. 2004. Trichomonas vaginalis: an irritating protozoan or an important viral co-factor. Biomedical Scientist. 48 (1), pp. 40-41.
Human papillomavirus: an overview
Rughooputh, S. and Greenwell, P. 2003. Human papillomavirus: an overview. Biomedical Scientist. 47, pp. 1070-1071.
Isolation of Neisseria gonorrhoeae-specific antibodies from a phage display library
Rughooputh, S. and Greenwell, P. 2003. Isolation of Neisseria gonorrhoeae-specific antibodies from a phage display library. Molecular and Cellular Proteomics. 2 (9), p. 758.
Bioinformatics in the identification of glycosidase genes in the Chlamydia genome
Greenwell, P. and Rughooputh, S. 2003. Bioinformatics in the identification of glycosidase genes in the Chlamydia genome. Molecular and Cellular Proteomics. 2 (9), p. 826.
Phage display antibody against gill proteins of the tropical clam
Gourdine, J.P., Smith-Ravin, E.J. and Greenwell, P. 2003. Phage display antibody against gill proteins of the tropical clam. Molecular and Cellular Proteomics. 2 (9), p. 759.
Incidence and prognostic significance of C-MPL expression in acute myeloid leukemia
Chelvatheebam, S., Langabeer, S., Hills, R., Greenwell, P. and Linch, D. 2003. Incidence and prognostic significance of C-MPL expression in acute myeloid leukemia. Leukemia Research. 27 (9), pp. 839-870. https://doi.org/10.1016/S0145-2126(03)00016-X
Beyond hybridoma technology: production of monoclonal antibodies by phage display
Greenwell, P. and Rughooputh, S. 2001. Beyond hybridoma technology: production of monoclonal antibodies by phage display. Biomedical Scientist. 45, pp. 574-575.
Isoforms of Na+, K+-ATPase in human prostate; specificity of expression and apical membrane polarization
Mobasheri, A., Oukrif, D., Dawodu, S.P., Sinha, M., Greenwell, P., Stewart, D., Djamgoz, M.B.A., Foster, C.S., Martin-Vasallo, P. and Mobasheri, R. 2001. Isoforms of Na+, K+-ATPase in human prostate; specificity of expression and apical membrane polarization. Histology and Histopathology. 16 (1), pp. 141-154.
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