Fatty acid metabolism of Mycobacterium tuberculosis: a double-edged sword

Exploring diverse frontiers: Advancements of bioactive 4-aminoquinoline-based molecular hybrids in targeted therapeutics and beyond
Ravindar, L., Hasbullah, S.A., Rakesh, K.P., Raheem, S., Agustar, H.K., Ismail, N., Ling, L.Y. and Hassan, N.I. 2023. Exploring diverse frontiers: Advancements of bioactive 4-aminoquinoline-based molecular hybrids in targeted therapeutics and beyond. European Journal of Medicinal Chemistry. 264 116043. https://doi.org/10.1016/j.ejmech.2023.116043

The Role of Fatty Acid Metabolism in Drug Tolerance of Mycobacterium tuberculosis
Gaspar Quinonez, C., Lee, J.J., Lim, J., Odell, M., Lawson, C.P., Anyogu, A., Raheem, S. and Eoh, H. 2022. The Role of Fatty Acid Metabolism in Drug Tolerance of Mycobacterium tuberculosis. mBio. 13 (1), pp. e03559-21. https://doi.org/10.1128/mbio.03559-21

Novel Inhibitors for Isocitrate Lyase as a Potent Antitubercular Agent for Mycobacterium Tuberculosis
Gaspar Quinonez, C. 2021. Novel Inhibitors for Isocitrate Lyase as a Potent Antitubercular Agent for Mycobacterium Tuberculosis. PhD thesis University of Westminster https://doi.org/10.34737/vvw3q

Prospecting for electrochemically-active hydrocarbon degrading microorganisms for use in bioelectrochemical remediation of petroleum hydrocarbons
Yayork, B., Anyogu, A. and Kyazze, G. 2021. Prospecting for electrochemically-active hydrocarbon degrading microorganisms for use in bioelectrochemical remediation of petroleum hydrocarbons. 5th EU-ISMET Conference (Online). Online 13 - 15 Sep 2021

Microorganisms and food safety risks associated with indigenous fermented foods from Africa
Anyogu, A., Olukorede, Ayomide, Anumudu, Christian, Onyeaka, Helen, Areo, Esther, Adewale, Obadina, Odimba, J. and Nwaiwu, O. 2021. Microorganisms and food safety risks associated with indigenous fermented foods from Africa. Food Control. 129 108227. https://doi.org/10.1016/j.foodcont.2021.108227

Microbiological hazards associated with food products imported from the Asia-Pacific region based on analysis of the Rapid Alert System for Food and Feed (RASFF) notifications
Dada, A.C, Somorin, Y.M, Ateba, C.B, Onyeaka, H, Anyogu, A., Azman Kasan, N and Odeyemi, O.A 2021. Microbiological hazards associated with food products imported from the Asia-Pacific region based on analysis of the Rapid Alert System for Food and Feed (RASFF) notifications. Food Control. 129 108243. https://doi.org/10.1016/j.foodcont.2021.108243

Microorganisms and food safety risks associated with indigenous fermented foods from Africa
Anyogu, A., Olukorede, A., Anumudu, C., Onyeaka, H., Areo, S., Obadina, A., Odimba, J.N. and Nwaiwu, O. 2021. Microorganisms and food safety risks associated with indigenous fermented foods from Africa. Food Control. 129 108227. https://doi.org/10.1016/j.foodcont.2021.108227

Bioelectrochemical remediation of petroleum hydrocarbons
Yayork, B., Anyogu, A. and Kyazze, G. 2021. Bioelectrochemical remediation of petroleum hydrocarbons. Society for Applied Microbiology Early Career Scientists conference. Online via Zoom 22 - 26 Mar 2021

Identification and characterisation of the lactic acid bacteria associated with the traditional fermentation of a dairy fermented product
Obioha, P., Ouoba, L.I.I., Anyogu, A., Awamaria, B., Atchia, S, Ojimelukwe, P.C, Sutherland, J.P and Ghoddusi, H. 2021. Identification and characterisation of the lactic acid bacteria associated with the traditional fermentation of a dairy fermented product. Brazilian Journal of Microbiology. 52, p. 869–881. https://doi.org/10.1007/s42770-021-00461-y

Letter to the Editor: Going beyond Learning and Listening to Meaningful Pursuit of Equity for Black Microbiologists
Adukwu, E., WaKobongo, M., Ekenna, O., Lungu, B, Anyogu, A. and Ujor, V. 2020. Letter to the Editor: Going beyond Learning and Listening to Meaningful Pursuit of Equity for Black Microbiologists. mBio. 11, pp. e02821-20. https://doi.org/10.1128/mbio.02821-20

Environmental heterogeneity of Staphylococcus species from alkaline fermented foods and associated toxins and antimicrobial resistance genetic elements
Ouoba, L.I.I., Vouidibio-Mbozo, A.B., Anyogu, A., Obioha, P.I., Lingani-Sawadogo, H., Sutherland, J.P., Jespersen, L. and Ghoddusi, H.B. 2019. Environmental heterogeneity of Staphylococcus species from alkaline fermented foods and associated toxins and antimicrobial resistance genetic elements. International Journal of Food Microbiology. 311, p. 108356 108356. https://doi.org/10.1016/j.ijfoodmicro.2019.108356

The Effects of Quorum Sensing Inhibitors on Multispecies Biofilms of the Oral Cavity
Garner, C., Anyogu, A., Kyazze, G. and Keshavarz, T. 2018. The Effects of Quorum Sensing Inhibitors on Multispecies Biofilms of the Oral Cavity . FST Doctoral Conference 2018. University of Westminster 19 Apr 2018

Potential use of electronic noses, electronic tongues and biosensors, as multisensor systems for spoilage examination in foods
Ghasemi-Varnamkhasti, M., Apetrei, C., Lozano, J. and Anyogu, A. 2018. Potential use of electronic noses, electronic tongues and biosensors, as multisensor systems for spoilage examination in foods. Trends in Food Science and Technology. 80, pp. 71-92. https://doi.org/10.1016/j.tifs.2018.07.018

Glutamate mediated metabolic neutralization mitigates propionate toxicity in intracellular Mycobacterium tuberculosis
Lee, J.J., Lim, J., Gao, S., Lawson, C.P., Odell, M., Raheem, S., Woo, J., Kang, S-H., Kang, S-S., Jeon, B-Y. and Eoh, H. 2018. Glutamate mediated metabolic neutralization mitigates propionate toxicity in intracellular Mycobacterium tuberculosis. Scientific Reports. 8 8506. https://doi.org/10.1038/s41598-018-26950-z

Investigation of the diversity and safety of the predominant Bacillus pumilus sensu lato and other Bacillus species involved in the alkaline fermentation of cassava leaves for the production of Ntoba Mbodi
Mbozoa, A.B.V., Kobawilaa, S.C., Anyogu, A., Awamariab, B., Louembea, D., Sutherland, J.P. and Ouoba, L.I.I. 2017. Investigation of the diversity and safety of the predominant Bacillus pumilus sensu lato and other Bacillus species involved in the alkaline fermentation of cassava leaves for the production of Ntoba Mbodi. Food Control. 82, pp. 154-162. https://doi.org/10.1016/j.foodcont.2017.06.018

Influence of soy fortification on microbial diversity during cassava fermentation and subsequent physicochemical characteristics of garri
Ahaotu, N.N., Anyogu, A., Obioha, P., Aririatu, L., Ibekwe, V., Oranusi, S., Sutherland, P. and Ouoba, L. 2017. Influence of soy fortification on microbial diversity during cassava fermentation and subsequent physicochemical characteristics of garri. Food Microbiology. 66, pp. 165-172. https://doi.org/10.1016/j.fm.2017.04.019

Signatures of anthocyanin metabolites identified in humans inhibit biomarkers of vascular inflammation in human endothelial cells
Warner, E.F., Smith, M.J., Zhang, Q., Raheem, S., O’Hagan, D., O'Connell, M.A. and Kay, C.D. 2017. Signatures of anthocyanin metabolites identified in humans inhibit biomarkers of vascular inflammation in human endothelial cells. Molecular Nutrition & Food Research. 61 (9) 1700053. https://doi.org/10.1002/mnfr.201700053

Influence of LAR and VAR on Para-Aminopyridine Antimalarials Targetting Haematin in Chloroquine-Resistance
Warhurst, D., Craig, J.C. and Raheem, S. 2016. Influence of LAR and VAR on Para-Aminopyridine Antimalarials Targetting Haematin in Chloroquine-Resistance. PLoS ONE. 11 (8) e0160091. https://doi.org/10.1371/journal.pone.0160091

Common Phenolic Metabolites of Flavonoids, but Not Their Unmetabolized Precursors, Reduce the Secretion of Vascular Cellular Adhesion Molecules by Human Endothelial Cells
Warner, E.F., Zhang, Q., Raheem, S., O’Hagan, D., O’Connell, M.A. and Kay, C.D. 2016. Common Phenolic Metabolites of Flavonoids, but Not Their Unmetabolized Precursors, Reduce the Secretion of Vascular Cellular Adhesion Molecules by Human Endothelial Cells. Journal of Nutrition. 146 (3), pp. 465-473. https://doi.org/10.3945/jn.115.217943

Effects of Fluconazole on the Metabolomic Profile of Candida albicans
Katragkou, A., Alexander, E.L., Eoh, H., Raheem, S., Roilides, E. and Walsh, T.J. 2016. Effects of Fluconazole on the Metabolomic Profile of Candida albicans. Journal of Antimicrobial Chemotherapy. 71 (3), pp. 635-640. https://doi.org/10.1093/jac/dkv381

Hanseniaspora jakobsenii sp. nov., a yeast isolated from Bandji, a traditional palm wine of Borassus akeassii
Ouoba, L.I.I., Nielsen, D.S., Anyogu, A., Kando, C., Diawara, B., Jespersen, L. and Sutherland, J.P. 2015. Hanseniaspora jakobsenii sp. nov., a yeast isolated from Bandji, a traditional palm wine of Borassus akeassii. International Journal of Systematic and Evolutionary Microbiology. 65, pp. 3576-3579. https://doi.org/10.1099/ijsem.0.000461

Lysinibacillus louembei sp. nov., a spore-forming bacterium isolated from Ntoba Mbodi, alkaline fermented leaves of cassava from the Republic of the Congo
Ouoba, L.I.I., Mbozo, A.B.V., Thorsen, L., Anyogu, A., Nielsen, D.S., Kobawila, S.C. and Sutherland, J.P. 2015. Lysinibacillus louembei sp. nov., a spore-forming bacterium isolated from Ntoba Mbodi, alkaline fermented leaves of cassava from the Republic of the Congo. International Journal of Systematic and Evolutionary Microbiology. 65, pp. 4256-4262. https://doi.org/10.1099/ijsem.0.000570

Flavonoid metabolites reduce tumor necrosis factor-α secretion to a greater extent than their precursor compounds in human THP-1 monocytes.
di Gesso, J.L., Kerr, J.S., Zhang, Q., Raheem, S., Yalamanchili, S.K., O’Hagan, D., Kay, C.D. and O'Connell, M.A. 2015. Flavonoid metabolites reduce tumor necrosis factor-α secretion to a greater extent than their precursor compounds in human THP-1 monocytes. Molecular Nutrition & Food Research. 59 (6), pp. 1143-1154. https://doi.org/10.1002/mnfr.201400799

Anthocyanins and their physiologically relevant metabolites alter the expression of IL-6 and VCAM-1 in CD40L and oxidized LDL challenged vascular endothelial cells
Amin, H.P., Czank, C., Raheem, S., Zhang, Q., Botting, N.P., Cassidy, A. and Kay, C.D. 2015. Anthocyanins and their physiologically relevant metabolites alter the expression of IL-6 and VCAM-1 in CD40L and oxidized LDL challenged vascular endothelial cells. Molecular Nutrition & Food Research. 59 (6), pp. 1095-1106. https://doi.org/10.1002/mnfr.201400803

Molecular characterisation and antimicrobial activity of bacteria associated with submerged lactic acid cassava fermentation
Anyogu, A., Awamaria, B., Sutherland, J.P. and Ouoba, L.I.I. 2014. Molecular characterisation and antimicrobial activity of bacteria associated with submerged lactic acid cassava fermentation. Food Control. 39, pp. 119-127. https://doi.org/10.1016/j.foodcont.2013.11.005

Methods for Isolating, Identifying, and Quantifying Anthocyanin Metabolites in Clinical Samples
de Ferrars, R.M., Czank, C., Saha, S., Needs, P.W., Zhang, Q., Raheem, S., Botting, N.P., Kroon, P.A. and Kay, C.D. 2014. Methods for Isolating, Identifying, and Quantifying Anthocyanin Metabolites in Clinical Samples. Analytical Chemistry. 86 (20), pp. 10052-10058. https://doi.org/10.1021/ac500565a

Arabidopsis AtPARK13, which confers thermotolerance, targets misfolded proteins
Basak, I., Pal, R., Patil, K.S., Dunne, A., Ho, H.P., Lee, S., Peiris, D., Maple-Grødem, J., Odell, M., Chang, E.J., Larsen, J.P. and Møller, S. 2014. Arabidopsis AtPARK13, which confers thermotolerance, targets misfolded proteins. Journal of Biological Chemistry. 289, pp. 14458-14469. https://doi.org/10.1074/jbc.M114.548156

ROS-mediated DJ-1 monomerization modulates intracellular trafficking involving Karyopherin-2
Bjørkblom, B., Maple-Grødem, J., Puno, M.R., Odell, M., Larsen, J.P. and Møller, S. 2014. ROS-mediated DJ-1 monomerization modulates intracellular trafficking involving Karyopherin-2. Molecular and Cellular Biology. 34 (16), pp. 3024-3040. https://doi.org/10.1128/MCB.00286-14

Arabidopsis AtPARK13, which confers thermotolerance, targets misfolded proteins
Basak, I., Pal, R., Patil, K.S., Dunne, A., Ho, H.P., Lee, S., Peiris, D., Maple-Grødem, J., Odell, M., Chang, E.J., Larsen, J.P. and Møller, S. 2014. Arabidopsis AtPARK13, which confers thermotolerance, targets misfolded proteins. Journal of Biological Chemistry. 289 (21), pp. 14458-69.

Proteomics analysis of Bacillus licheniformis in response to oligosaccharides elicitors
Reffatti, P.F., Roy, I., Odell, M. and Keshavarz, T. 2014. Proteomics analysis of Bacillus licheniformis in response to oligosaccharides elicitors. Enzyme Microb Technol. . 61-62, pp. 61-66. https://doi.org/10.1016/j.enzmictec.2014.03.007

Evidence for the involvement of intracellular Ca 2+ ions in the elicitation mechanism of Bacillus Licheniformis
Reffatti, P., Roy, I., Odell, M. and Keshavarz, T. 2013. Evidence for the involvement of intracellular Ca 2+ ions in the elicitation mechanism of Bacillus Licheniformis. Journal of Molecular Microbiology and Biotechnology. OnlineFirst. https://doi.org/10.1159/000351515

The neuroprotective role of catalase overexpression in SH-SY5Y cells against beta-amyloid and H2O2 toxicity
Chilumuri, A., Odell, M. and Milton, N.G.N. 2013. The neuroprotective role of catalase overexpression in SH-SY5Y cells against beta-amyloid and H2O2 toxicity. Alzheimer's & Dementia. 9 (4), p. P361.

Structure of Cu(I)-bound DJ-1 reveals a biscysteinate metal binding site at the homodimer interface: insights into mutational inactivation of DJ-1 in parkinsonism
Puno, M.R., Patel, N.A., Møller, S.G., Robinson, C.V., Moody, P.C.E. and Odell, M. 2013. Structure of Cu(I)-bound DJ-1 reveals a biscysteinate metal binding site at the homodimer interface: insights into mutational inactivation of DJ-1 in parkinsonism. Journal of the American Chemical Society. 135 (43), p. 15974–15977. https://doi.org/10.1021/ja406010m

Benzothiazole aniline-tetra(ethylene glycol) and 3-amino-1,2,4-triazole inhibit neuroprotection against amyloid peptides by catalase overexpression in vitro
Chilumuri, A., Odell, M. and Milton, N.G.N. 2013. Benzothiazole aniline-tetra(ethylene glycol) and 3-amino-1,2,4-triazole inhibit neuroprotection against amyloid peptides by catalase overexpression in vitro. ACS chemical neuroscience. 4 (11), pp. 1501-1512. https://doi.org/10.1021/cn400146a

Is quorum sensing involved in lovastatin production in the filamentous fungus Aspergillus terreus?
Raina, S., De Vizio, D., Palonen, E.K., Odell, M., Brandt, A.M., Soini, J.T. and Keshavarz, T. 2012. Is quorum sensing involved in lovastatin production in the filamentous fungus Aspergillus terreus? Process Biochemistry. 47 (5), pp. 843-852. https://doi.org/10.1016/j.procbio.2012.02.021

Survival of inoculated Salmonella on the shell of hens' eggs and its potential significance
Botey-Saló, P., Anyogu, A., Varnam, A.H. and Sutherland, J.P. 2012. Survival of inoculated Salmonella on the shell of hens' eggs and its potential significance. Food Control. 28 (2), pp. 463-469. https://doi.org/10.1016/j.foodcont.2012.05.033

Flavonoid metabolism: the synthesis of phenolic glucuronides and sulfates as candidate metabolites for bioactivity studies of dietary flavonoids
Zhang, Q., Raheem, S., Botting, N.P., Slawin, A.M.Z., Kay, C.D. and O’Hagan, D. 2012. Flavonoid metabolism: the synthesis of phenolic glucuronides and sulfates as candidate metabolites for bioactivity studies of dietary flavonoids. Tetrahedron. 68, pp. 4194-4201. https://doi.org/10.1016/j.tet.2012.03.100

Identification, cloning and characterization of two N-acetylgalactosamine binding lectins from the albumen gland of Helix pomatia
Markiv, A., Peiris, D., Curley, G.P., Odell, M. and Dwek, M. 2011. Identification, cloning and characterization of two N-acetylgalactosamine binding lectins from the albumen gland of Helix pomatia. Journal of Biological Chemistry. 286 (23), pp. 20260-20266. https://doi.org/10.1074/jbc.M110.184515

Total synthesis of 3,5-O-dicaffeoylquinic acid and its derivatives
Raheem, S., Botting, Nigel P., Williamson, G. and Barron, D. 2011. Total synthesis of 3,5-O-dicaffeoylquinic acid and its derivatives. Tetrahedron Letters. 52 (52), p. 7175. https://doi.org/10.1016/j.tetlet.2011.10.127

Quorum sensing as a method for improving sclerotiorin production in Penicillium sclerotiorum
Raina, S., Odell, M. and Keshavarz, T. 2010. Quorum sensing as a method for improving sclerotiorin production in Penicillium sclerotiorum. Journal of Biotechnology. 148 (2-3), pp. 91-98. https://doi.org/10.1016/j.jbiotec.2010.04.009

Cancer prognostication using a recombinant form of the lectin from Helix pomatia agglutinin
Dwek, M., Markiv, A. and Odell, M. 2009. Cancer prognostication using a recombinant form of the lectin from Helix pomatia agglutinin. Glycobiology. 19 (11), p. 1318. https://doi.org/10.1093/glycob/cwp135

Microbial quorum sensing: a tool or a target for antimicrobial therapy?
Raina, S., De Vizio, D., Odell, M., Clements, M.O., Vanhulle, S. and Keshavarz, T. 2009. Microbial quorum sensing: a tool or a target for antimicrobial therapy? Biotechnology and Applied Biochemistry. 54 (2), pp. 65-84. https://doi.org/10.1042/BA20090072

Polyhydroxyalkanoate synthase in Bacillus cereus SPV, a class IV PHA synthase
Philip, S.E., Odell, M., Keshavarz, T. and Roy, I. 2008. Polyhydroxyalkanoate synthase in Bacillus cereus SPV, a class IV PHA synthase. 11th International Symposium on Biodegradable Polyesters. Massey University in Auckland, New Zealand 23 - 26 Nov 2008

Structural basis for nick recognition by a minimal pluripotent DNA ligase
Nair, P.A., Nandakumar, J., Smith, P., Odell, M., Lima, C.D. and Shuman, S. 2007. Structural basis for nick recognition by a minimal pluripotent DNA ligase. Nature Structural and Molecular Biology. 14 (8), pp. 770-778. https://doi.org/10.1038/nsmb1266

Polyhydroxy-alkanoates - the biodegradable polymers
Philip, S.E., Odell, M., Keshavarz, T. and Roy, I. 2007. Polyhydroxy-alkanoates - the biodegradable polymers. International Conference on Biodegradable Polymers: their production, characterisation and application. SCI, London 10 Dec 2007

Circadian orchestration of the hepatic proteome
Reddy, A.B., Karp, N.A., Maywood, E.S., Sage, E.A., Deery, M., O'Neill, J.S., Wong, G.K.Y., Chesham, J., Odell, M., Lilley, K.S., Kyriacou, C.P. and Hastings, M.H. 2006. Circadian orchestration of the hepatic proteome. Current Biology. 16 (11), pp. 1107-1115. https://doi.org/10.1016/j.cub.2006.04.026

Polyhydroxyalkanoate synthases: the enzymes involved in biodegradable polymer synthesis
Valappil, S.P., Philip, S.E., Odell, M., Keshavarz, T. and Roy, I. 2005. Polyhydroxyalkanoate synthases: the enzymes involved in biodegradable polymer synthesis. Proceedings of Frontiers in Chemical Biology: Mechanistic Enzymology and Biocatalysis. Exeter, UK 31 Aug - 02 Sep 2005

DNA Ligases: Stuctures
Odell, M. 2004. DNA Ligases: Stuctures. in: Lennarz, W.J. and Lane, M.D. (ed.) Encyclopedia of biological chemistry Amsterdam, Netherlands Elsevier.

No ARM in it? (reply to Kippert and Gerloff)
Kyriacou, C.P. and Odell, M. 2004. No ARM in it? (reply to Kippert and Gerloff). Current Biology. 14 (16), pp. R652-R653. https://doi.org/10.1016/j.cub.2004.08.009

Analysis of the DNA joining repertoire of Chlorella virus DNA ligase and a new crystal structure of the ligase-adenylate intermediate
Odell, M., Malinina, L., Sriskanda, V., Teplova, M. and Shuman, S. 2003. Analysis of the DNA joining repertoire of Chlorella virus DNA ligase and a new crystal structure of the ligase-adenylate intermediate. Nucleic Acids Research. 31 (17), pp. 5090-5100. https://doi.org/10.1093/nar/gkg665

Structure-based experimental confirmation of biochemical function to a methyltransferase, MJ0882, from hyperthermophile Methanococcus jannaschii
Huang, L., Hung, L., Odell, M., Yokota, H., Kim, R. and Kim, S.H. 2002. Structure-based experimental confirmation of biochemical function to a methyltransferase, MJ0882, from hyperthermophile Methanococcus jannaschii. Journal of Structural and Functional Genomics. 2 (3), pp. 121-127. https://doi.org/10.1023/A:1021279113558

The Drosophila clock protein Timeless is a member of the Arm/HEAT family
Vodovar, N., Clayton, J., Costa, R., Odell, M. and Kyriacou, C.P. 2002. The Drosophila clock protein Timeless is a member of the Arm/HEAT family. Current Biology. 12 (18), pp. R610-R611. https://doi.org/10.1016/S0960-9822(02)01130-2

Crystal structure of eukaryotic DNA ligase–adenylate illuminates the mechanism of nick sensing and strand joining
Odell, M., Sriskanda, V., Shuman, S. and Nikolov, D.B. 2000. Crystal structure of eukaryotic DNA ligase–adenylate illuminates the mechanism of nick sensing and strand joining. Molecular Cell. 6 (5), pp. 1183-1193.

Footprinting of Chlorella virus DNA ligase bound at a nick in duplex DNA
Odell, M. and Shuman, S. 1999. Footprinting of Chlorella virus DNA ligase bound at a nick in duplex DNA. Journal of Biological Chemistry. 274 (20), pp. 14032-14039.