Title | Hydroxy double salts intercalated with Mn(II) complexes as potential contrast agents |
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Authors | Bligh, S.W.A., Jin, M., Spillane, D.E.M., Geraldes, C.F.G.C. and Williams, G.R. |
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Abstract | A series of Mn(II) aminophosphonate complexes were successfully synthesized and intercalated into the hydroxy double salt [Zn5(OH)8]Cl2·yH2O. Complex incorporation led to an increase in the interlayer spacing from 7.8 to 10–12 Å. Infrared spectroscopy showed the presence of the characteristic vibration peaks of the Mn(II) complexes in the intercalates' spectra, indicating successful incorporation. The complex-loaded composites had somewhat lower proton relaxivities than the pure complexes. Nevertheless, these intercalates may have use as MRI contrast agents for patients with poor kidney function, where traditional Gd(III)-based contrast agents cause severe renal failure. |
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Keywords | Hydroxy double salt; Magnetic resonance imaging; Contrast agent; Mn complexes |
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Journal | Solid State Sciences |
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Journal citation | 53, p. 9–16 |
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ISSN | 1293-2558 |
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Year | 2016 |
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Publisher | Elsevier |
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Accepted author manuscript | |
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Digital Object Identifier (DOI) | https://doi.org/10.1016/j.solidstatesciences.2015.12.024. |
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Publication dates |
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Published | 05 Jan 2016 |
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Supplementary data or files | File |
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