Withania somnifera Root Extract Enhances Chemotherapy through ‘Priming’

Henley, A., Yang L., Chuang K-L., Sahuri Arisoylu, M., Wu, L-H., Bligh, S.W.A. and Bell, J.D. 2017. Withania somnifera Root Extract Enhances Chemotherapy through ‘Priming’. PLoS ONE.

TitleWithania somnifera Root Extract Enhances Chemotherapy through ‘Priming’
AuthorsHenley, A., Yang L., Chuang K-L., Sahuri Arisoylu, M., Wu, L-H., Bligh, S.W.A. and Bell, J.D.
Abstract

Withania somnifera extracts are known for their anti-cancerous, anti-inflammatory and antioxidative properties. One of their mechanisms of actions is to modulate mitochondrial function through increasing oxidative stress. Recently ‘priming’ has been suggested as a potential mechanism for enhancing cancer cell death. In this study we demonstrate that ‘priming’, in HT-29 colon cells, with W. somnifera root extract increased the potency of the chemotherapeutic agent cisplatin. We have also showed the W. somnifera root extract enhanced mitochondrial dysfunction and that the underlying mechanism of ‘priming’ was selectively through increased ROS. Moreover, we showed that this effect was not seen in non-cancerous cells.

JournalPLoS ONE
ISSN1932-6203
Year2017
PublisherPublic Library of Science
Publisher's versionjournal.pone.0170917.pdf
Digital Object Identifier (DOI)doi:10.1371/journal.pone.0170917
Publication dates
Published27 Jan 2017
LicenseCC BY 4.0

Related outputs

The effects of dietary supplementation with inulin and inulin-propionate ester on hepatic steatosis in adults with non-alcoholic fatty liver disease
Chambers, E.S., Byrne, C.S., Rugyendo, A., Morrison, D.J., Preston, T., Tedford, M.C., Bell, J.D., Thomas, E.L., Akbar, A.N., Riddell, N.E., Sharma, R., Thursz, M.R., Manousou, P. and Frost, G. 2018. The effects of dietary supplementation with inulin and inulin-propionate ester on hepatic steatosis in adults with non-alcoholic fatty liver disease. Diabetes, Obesity and Metabolism.

Cannabidiol (CBD) is a Novel Inhibitor for Exosome and Microvesicle (EMV) Release in Cancer
Kosgodage, U., Mould, R., Henley, A., Nunn, A.V.W., Guy, G.W., Thomas, E.L., Inal, J.M., Bell, J.D. and Lange, S. 2018. Cannabidiol (CBD) is a Novel Inhibitor for Exosome and Microvesicle (EMV) Release in Cancer. Frontiers in Pharmacology. 9, p. 889.

Reference range of liver corrected T1 values in a population at low risk for fatty liver disease-a UK Biobank sub-study, with an appendix of interesting cases
Mojtahed, A., Kelly, C.J., Herlihy, A.H., Kin, S., Wilman, H.R., McKay, A., Kelly, M., Milanesi, M., Neubauer, S,, Thomas, E.L., Bell, J.D., Banerjee, R. and Harisinghani, M. 2018. Reference range of liver corrected T1 values in a population at low risk for fatty liver disease-a UK Biobank sub-study, with an appendix of interesting cases. Abdominal Radiology.

Plasma metabolome analysis identifies distinct human metabotypes in the postprandial state with different susceptibility to weight loss–mediated metabolic improvements
Fiamoncini, J., Rundle, M., Gibbons, H., Thomas, E.L., Geillinger-Kästle, K., Bunzel, D., Trezzi, J.P., Kiselova-Kaneva, J., Wopereis, S., Wahrheit, J., Kulling, S.E., Hiller, K., Sonntag, D., Ivanova, D., van Ommen, B, Frost, G., Brennan, L., Bell, J.D. and Daniel, H. 2018. Plasma metabolome analysis identifies distinct human metabotypes in the postprandial state with different susceptibility to weight loss–mediated metabolic improvements. FASEB Journal.

Body Composition Profiling in the UK Biobank Imaging Study
Linge, J., Borger Magnus, West, J., Tuthill, T., Miller, M.R., Dumitriu, A., Thomas, E.L., Romu, T., Tunón, P., Bell, J.D. and Leinhard, O.D. 2018. Body Composition Profiling in the UK Biobank Imaging Study. Obesity.

Advanced body composition assessment: from body mass index to body composition profiling
Borga, M., West, J., Bell, J.D., Harvey, N.C., Romu, T., Heymsfield, S.B. and Leinhard, O.D. 2018. Advanced body composition assessment: from body mass index to body composition profiling. Journal of Investigative Medicine. 66 (5), pp. 887-895.

Rifaximin in Non-Alcoholic Steatohepatitis: An Open-Label Pilot Study
Cobbold, J.F.L., Atkinson, S., Marchesi, J.R., Smith, A., Wai, S.N., Stove, J., Shojaee-Moradie, F., Jackson, N.C., Umpleby, A.M., Fitzpatrick, J., Thomas, E.L., Bell, J.D., Holmes, E., Taylor-Robinson, S.D., Goldin, R.D., Yee, M.S., Anstee, Q.M. and Thursz, M.R. 2018. Rifaximin in Non-Alcoholic Steatohepatitis: An Open-Label Pilot Study. Hepatology Research. 48 (1), pp. 69-77.

The effect of silymarin on chondrocytes
Can, V.C., Abouelnour, A., Locke, I.C., Bligh, S.W.A. and Getting, S.J. 2017. The effect of silymarin on chondrocytes. ICMAN/ IUPHAR Natural Products. Aberdeen, Scotland 27 - 29 Sep 2017 Elsevier.

Impact of liver fat on the differential partitioning of hepatic triacylglycerol into VLDL subclasses on high and low sugar diets
Umpleby, A.M., Shoajee-Moradie, F., Fielding, F., Li, X., Marino, A., Alsini, N, Isherwood, C, Jackson, N.C., Ahmad, A., Stolinski, M., Lovegrove, J.A., Johnsen, S., Mendis, A., Wright, J., Wilinska, M.E., Hovorka, R., Bell, J.D., Thomas, E.L., Frost, G.S. and Griffin, B.A. 2017. Impact of liver fat on the differential partitioning of hepatic triacylglycerol into VLDL subclasses on high and low sugar diets. Clinical Science. 131 (21), pp. 2561-2573.

The Potential of Omega-3 Supplementation to Reduce Muscle-Inflammation after Muscle-Damaging Exercise
Kyriakidou, Y., Kantorovich, R.C., Bell, J.D., Monterisi, S. and Dolci, M.A. 2017. The Potential of Omega-3 Supplementation to Reduce Muscle-Inflammation after Muscle-Damaging Exercise. ACSM Annual Meeting, World Congress on Exercise is Medicine & World Congress on the Basic Science of Exercise and the Brain. Denver, Colorado 30 May - 03 Jun 2017 American College of Sports Medicine.

Cationic lipid-based nanoparticles mediate functional delivery of acetate to tumor cells in vivo leading to significant anticancer effects
Brody, L.P., Sahuri Arisoylu, M., Parkinson, J.R., Parkes, H.G., So, P-W, Hajji, N, Thomas, E.L., Frost, G.S., Miller, A.D. and Bell, J.D. 2017. Cationic lipid-based nanoparticles mediate functional delivery of acetate to tumor cells in vivo leading to significant anticancer effects. International Journal of Nanomedicine. 12, pp. 6677-6685.

The Hormesis of Thinking: A Deeper Quantum Thermodynamic Perspective?
Nunn, A.V.W., Guy, G.W. and Bell, J.D. 2017. The Hormesis of Thinking: A Deeper Quantum Thermodynamic Perspective? International Journal of Neurorehabilitation. 4 (3), p. 272.

Thyroid Hormone Receptor Beta in the Ventromedial Hypothalamus Is Essential for the Physiological Regulation of Food Intake and Body Weight
Hameed, S., Patterson, M., Dhillo, W.S., Rahman, S.A., Ma, Y., Holton, C., Gogakos, A., Yeo, G.S.H., Lam, B.Y.H., Polex-Wolf, J., Fenske, W., Bell, J.D., Anastasovska, J., Samarut, J., Bloom, S.R., Bassett, J.H.D., Williams, G.R. and Gardiner, J.V. 2017. Thyroid Hormone Receptor Beta in the Ventromedial Hypothalamus Is Essential for the Physiological Regulation of Food Intake and Body Weight. Cell Reports. 19 (11), pp. 2202-2219.

A Framework for Morphological Feature Extraction of Organs from MR Images for Detection and Classification of Abnormalities
Villarini, B., Asaturyan, H., Thomas, E.L., Mould, R. and Bell, J.D. 2017. A Framework for Morphological Feature Extraction of Organs from MR Images for Detection and Classification of Abnormalities. Proceedings of the 30th IEEE International Symposium on Computer-Based Medical Systems (CBMS’17). Thessaloniki, Greece 22 - 24 Jun 2017 IEEE .

Psoas major cross-sectional area: A potential marker of cardiorespiratory fitness
Fitzpatrick, J., Chambers, E.S., Parkinson, J.R.C., Frost, G., Bell, J.D. and Thomas, E.L. 2017. Psoas major cross-sectional area: A potential marker of cardiorespiratory fitness. International Journal of Clinical and Experimental Physiology. 4 (1), pp. 15-20.

Metabolic dysfunction following weight cycling in male mice
Schofield, S.E., Parkinson, J., Henley, A., Sahuri Arisoylu, M., Sanchez-Canon, G.J. and Bell, J.D. 2017. Metabolic dysfunction following weight cycling in male mice. International Journal of Obesity. 41 (3), pp. 402-411.

Characterisation of liver fat in the UK Biobank cohort
Wilman, H., Kelly, M., Garratt, S., Matthews, P., Milanesi, M., Herlihy, A.H., Gyngell, M, Neubauer, S, Bell, J.D., Banerjee, R and Thomas, E.L. 2017. Characterisation of liver fat in the UK Biobank cohort. PLoS ONE. 12 (2), p. e0172921.

Core-sheath nanofibers as drug delivery system for thermoresponsive controlled release
Lv, Y., Pan, Q., Bligh, S.W.A., Li, H., Wu, H, Sang, Qingqing and Zhu, Li-Min 2017. Core-sheath nanofibers as drug delivery system for thermoresponsive controlled release. Journal of Pharmaceutical Sciences. 106 (5), pp. 1258-1265.

Effect of energy restriction and physical exercise intervention on phenotypic flexibility as examined by transcriptomics analyses of mRNA from adipose tissue and whole body magnetic resonance imaging
Lee, S., Norheim, F., Langleite, T.M., Noreng, H.J., Storås, T.H., Afman, L.A., Frost, G., Bell, J.D., Thomas, E.L., Kolnes, K.J., Tangen, D.S., Stadheim, H.K., Gilfillan, G.D., Gulseth, H.L., Birkeland, K.I., Jensen, J., Drevon, C.A. and Holen, T. 2016. Effect of energy restriction and physical exercise intervention on phenotypic flexibility as examined by transcriptomics analyses of mRNA from adipose tissue and whole body magnetic resonance imaging. Physiological Reports. 4 (21), p. e13019.

Feasibility of MR-Based Body Composition Analysis in Large Scale Population Studies
West, J., Leinhard, O.D., Romu, T., Collins, R., Garratt, S., Bell, J.D., Borga, M. and Thomas, E.L. 2016. Feasibility of MR-Based Body Composition Analysis in Large Scale Population Studies. PLoS ONE. 11 (9).

The Quantum Mitochondrion and Optimal Health
Bell, J.D., Nunn, A.V.W. and Guy, G.W. 2016. The Quantum Mitochondrion and Optimal Health. Biochemical Society Transactions. 44 (4), pp. 1101-1110.

Link between increased gut hormones signaling satiety and reduced food reward following gastric bypass surgery for obesity
Goldstone, A.P., Miras, A.D., Scholtz, S., Jackson, S., Neff, K.J., Pénicaud, L., Geoghegan, J., Chhina, N., Durighel, G., Bell, J.D., Meillon, S. and le Roux, C.W. 2016. Link between increased gut hormones signaling satiety and reduced food reward following gastric bypass surgery for obesity. Journal of Clinical Endocrinology and Metabolism. 101 (2), pp. 599-609.

Synergy between histone deacetylase inhibitors and DNA- damaging agents is mediated by histone deacetylase 2 in colorectal cancer
Alzoubi, S., Brody, L., Rahman, S., Mahul-Mellier, A.L., Mercado, N., Ito, K., El-Bahrawy, M., Silver, A., Boobis, A., Bell, J.D. and Hajji, N. 2016. Synergy between histone deacetylase inhibitors and DNA- damaging agents is mediated by histone deacetylase 2 in colorectal cancer. Oncotarget . 7 (28), pp. 44505-44521.

Exercise Training Reduces Liver Fat and Increases Rates of VLDL Clearance, but not VLDL Production in NAFLD
Shojaee-Moradie, F., Cuthbertson, D.J., Barrett, M., Jackson, N.C., Herring, R, Thomas, E.L., Bell, J.D., Kemp, G.J., Wright, J. and Umpleby, A.M. 2016. Exercise Training Reduces Liver Fat and Increases Rates of VLDL Clearance, but not VLDL Production in NAFLD. Journal of Clinical Endocrinology and Metabolism. 101 (11), pp. 4219-4228.

Efficacy and Safety of Cannabidiol and Tetrahydrocannabivarin on Glycemic and Lipid Parameters in Patients With Type 2 Diabetes: A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Pilot Study
Jadoon, K.A., Ratcliffe, S.H., Barrett, D.A., Thomas, E.L., Stott, C., Bell, J.D., O’Sullivan S.E. and Tan, G.D. 2016. Efficacy and Safety of Cannabidiol and Tetrahydrocannabivarin on Glycemic and Lipid Parameters in Patients With Type 2 Diabetes: A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Pilot Study. Diabetes Care. 39 (10), pp. 1777-1786.

Comprehensive metabolite profiling of Plantaginis Semen using ultra high performance liquid chromatography with electrospray ionization quadrupole time-of-flight tandem mass spectrometry coupled with elevated energy technique
Wang, D., Qi, M., Yang, Q., Tong, R, Wang, R, Bligh, S.W.A., Yang, L. and Wang, Z. 2016. Comprehensive metabolite profiling of Plantaginis Semen using ultra high performance liquid chromatography with electrospray ionization quadrupole time-of-flight tandem mass spectrometry coupled with elevated energy technique. Journal of Separation Science. 39 (10), pp. 1842-1852.

Theranostic Fibers for Simultaneous Imaging and Drug Delivery
Bligh, S.W.A., Williams, G.R., Yu, D.G., Jin, M. and Geraldes, C. 2016. Theranostic Fibers for Simultaneous Imaging and Drug Delivery. Molecular Pharmaceutics. 13 (7), pp. 2457-2465.

Effect of Short-Chain Fatty Acid Acetate on Colon Cancer
Sahuri Arisoylu, M., Bell, J.D. and J. D. Bell 2016. Effect of Short-Chain Fatty Acid Acetate on Colon Cancer. Experimental Biology. San Diego 02 Apr 2016

Nutritional Evaluation and Optimisation in Neonates: a randomized, double-blind controlled trial of amino acid regimen and intravenous lipid composition in preterm parenteral nutrition
Uthaya, S.N., Liu, X., Babalis, D., Doré, C.J., Caroline, J., Warwick, J., Bell, J.D., Thomas, E.L., Ashby, D., Durighel, G., Ederies, A., Yanez-Lopez, M. and Modi, N. 2016. Nutritional Evaluation and Optimisation in Neonates: a randomized, double-blind controlled trial of amino acid regimen and intravenous lipid composition in preterm parenteral nutrition. American Journal of Clinical Nutrition. 106 (3), pp. 1443-1452.

Nutritional Evaluation and Optimisation in Neonates (NEON) trial of amino acid regimen and intravenous lipid composition in preterm parenteral nutrition: a randomised double-blind controlled trial
Uthaya, S.N., Liu, X., Babalis, D., Doré, C.J., Warwick, J., Bell, J.D., Thomas, E.L., Ashby, D., Durighel, G., Ederies, A., Yanez-Lopez, M. and Modi, N. 2016. Nutritional Evaluation and Optimisation in Neonates (NEON) trial of amino acid regimen and intravenous lipid composition in preterm parenteral nutrition: a randomised double-blind controlled trial. Efficacy and Mechanism Evaluation. 3 (2).

Reprogramming of hepatic fat accumulation and 'browning' of adipose tissue by the short-chain fatty acid acetate
Sahuri Arisoylu, M., Brody, L., Parkinson, J., Parkes, H.G., Navaratnam, N., Miller, A.D., Thomas, E.L., Frost, G.S. and Bell, J.D. 2016. Reprogramming of hepatic fat accumulation and 'browning' of adipose tissue by the short-chain fatty acid acetate. International Journal of Obesity.

Electrospun pH-sensitive core–shell polymer nanocomposites fabricated using a tri-axial process
Bligh, S.W.A., Yang, C., Yu, D.G., Pan, D., Liu, X.-K., Wang, X. and Williams, G.R. 2016. Electrospun pH-sensitive core–shell polymer nanocomposites fabricated using a tri-axial process. Acta Biomaterialia. 35, pp. 77-86.

Electrospun Contrast Agent-Loaded Fibers for Colon-Targeted MRI
Bligh, S.W.A., Jin, M., Yu, D.G., Wang, X., Geraldes, C.F.G.C. and Williams, G.R. 2016. Electrospun Contrast Agent-Loaded Fibers for Colon-Targeted MRI. Advanced Healthcare Materials. 5 (8), pp. 977-985.

Medicated Janus fibers fabricated using a Teflon-coated side-by-side spinneret
Bligh, S.W.A., Yu, D.G., Shen, C.Y., Jin, M., Williams, G.R., Zou, H. and Wang, X. 2016. Medicated Janus fibers fabricated using a Teflon-coated side-by-side spinneret. Colloids and Surfaces B: Biointerfaces. 138, p. 110–116.

Hydroxy double salts intercalated with Mn(II) complexes as potential contrast agents
Bligh, S.W.A., Jin, M., Spillane, D.E.M., Geraldes, C.F.G.C. and Williams, G.R. 2016. Hydroxy double salts intercalated with Mn(II) complexes as potential contrast agents. Solid State Sciences. 53, p. 9–16.

Liver fat in adults with GH deficiency: comparison to matched controls and the effect of GH replacement
Meienberg, F., Yee, M., Johnston, D.G., Cox, J., Robinson, S., Bell, J.D., Thomas, E.L., Taylor-Robinson, S.D. and Godsland, I.F. 2016. Liver fat in adults with GH deficiency: comparison to matched controls and the effect of GH replacement. Clinical Endocrinology. 85 (1), pp. 76-84.

Targeted delivery and controlled release of doxorubicin into cancer cells using a multifunctional graphene oxide
Bligh, S.W.A., Lv, Y., Tao, L., Yang, H., Pan, Q. and Zhua, L. 2016. Targeted delivery and controlled release of doxorubicin into cancer cells using a multifunctional graphene oxide. Materials Science and Engineering: C. 59, p. 652–660.

Gd(III) complexes intercalated into hydroxy double salts as potential MRI contrast agents
Bligh, S.W.A., Jin, M., Spillane, D.E.M., Geraldes, C.F.G.C. and Williams, G.R. 2015. Gd(III) complexes intercalated into hydroxy double salts as potential MRI contrast agents. Dalton Transactions: The International Journal for Inorganic, Organometallic and Bioinorganic Chemistry. 44 (47), pp. 20728-20734.

Body fat MRS
Thomas, E.L. and Bell, J.D. 2015. Body fat MRS. eMagRes. 4 (3), pp. 663-672.

A randomized controlled trial: the effect of inulin on weight management and ectopic fat in subjects with prediabetes.
Guess, N.D., Dornhorst, A., Oliver, N., Bell, J.D., Thomas, E.L. and Frost, G.S. 2015. A randomized controlled trial: the effect of inulin on weight management and ectopic fat in subjects with prediabetes. Nutrition & Metabolism. 12 (36).

Validation of a fast method for quantification of intra-abdominal and subcutaneous adipose tissue for large-scale human studies
Borga, M., Thomas, E.L., Romu, T., Rosander, J., Fitzpatrick, J., Leinhard, O.D., Bell, J.D. and Borger Magnus 2015. Validation of a fast method for quantification of intra-abdominal and subcutaneous adipose tissue for large-scale human studies. NMR in Biomedicine. 28 (12), pp. 1747-1753.

Dissociation between exercise-induced reduction in liver fat and changes in hepatic and peripheral glucose homeostasis in obese patients with Non-Alcoholic Fatty Liver Disease.
Cuthbertson, D.J., Shojaee-Moradie, F., Sprung, V.S., Jones, H., Pugh, C.J., Richardson, P., Kemp, G.J., Barrett, M., Jackson, N.C., Thomas, E.L., Bell, J.D. and Umpleby, A.M. 2015. Dissociation between exercise-induced reduction in liver fat and changes in hepatic and peripheral glucose homeostasis in obese patients with Non-Alcoholic Fatty Liver Disease. Clinical Science. 130 (2), pp. 93-104.

Effects of targeted delivery of propionate to the human colon on appetite regulation, body weight maintenance and adiposity in overweight adults.
Chambers, E.S., Viardot, A., Psichas, A., Morrison, D.J., Murphy, K.G., Zac-Varghese, S.E., MacDougall, K., Preston, T., Tedford, C., Finlayson, G.S., Blundell, J.E., Bell, J.D., Thomas, E.L., Mt-Isa, S., Ashby, D., Gibson, G.R., Kolida, S., Dhillo, W.S., Bloom, S.R., Morley, W., Clegg, S., Frost, G.S. and Sagen E K Zac-Varghese 2015. Effects of targeted delivery of propionate to the human colon on appetite regulation, body weight maintenance and adiposity in overweight adults. Gut. 64 (11), pp. 1744-54.

Nanofibers fabricated using triaxial electrospinning as zero order drug delivery systems
Yu, D.G., Wang, X., Li, X.-Y., Yang, J.-H., Bligh, S.W.A. and Williams, G.R. 2015. Nanofibers fabricated using triaxial electrospinning as zero order drug delivery systems. ACS Applied Materials & Interfaces. 7 (33), p. 18891–18897.

A thin-layer chromatography-bioautographic method for detecting dipeptidyl peptidase IV inhibitors in plants
Bligh, S.W.A., Gu, L.-H., Liao, L.P., Hu, H.J., Wang, C.-H., Chou, G.-X. and Wang, Z.T. 2015. A thin-layer chromatography-bioautographic method for detecting dipeptidyl peptidase IV inhibitors in plants. Journal of Chromatography A. 1411 (11), p. 116–122.

Structure-inhibition relationship of phenylethanoid glycosides on angiotensin-converting enzyme using ultra-performance liquid chromatography-tandem quadrupole mass spectrometry
Bligh, S.W.A., Li, P., Qi, M., Hu, H., Liu, Q., Yang, Q., Wang, D., Guo, F., Wang, Z. and Yang, L. 2015. Structure-inhibition relationship of phenylethanoid glycosides on angiotensin-converting enzyme using ultra-performance liquid chromatography-tandem quadrupole mass spectrometry. RSC Advances. 5 (64), pp. 51701-51707.

Electrospun medicated shellac nanofibers for colon-targeted drug delivery
Wang, X., Yu, D.G., Li, X.-Y., Bligh, S.W.A. and Williams, G.R. 2015. Electrospun medicated shellac nanofibers for colon-targeted drug delivery. International Journal of Pharmaceutics. 490 (1-2), pp. 384-390.

Circulating pancreatic polypeptide concentrations predict visceral and liver fat content
Sam Amir, H., Sleeth Michelle, L., Thomas, E.L., Daud Norlida, M., Chambers Edward, Shojaee-Moradie Fariba, Umpleby, A.M., le Roux, C.W., Bech Paul, Busbridge Mark, Laurie Rosemary Cuthbertson Daniel, J., Buckley Adam Ghatei Mohammad, A., Bloom, S.R., Frost, G.S., Bell, J.D., Murphy, K.G., Ismail Nurhafzan, Shoajee-Moradie Fariba, Goldstone, A.P., Cuthbertson, D.J. and Ghatei, M.A. 2015. Circulating pancreatic polypeptide concentrations predict visceral and liver fat content. Journal of Clinical Endocrinology and Metabolism. 100 (3), pp. 1048-1052.

Sexual dimorphism in relation to adipose tissue and intrahepatocellular lipid deposition in early infancy
Gale, C., Jeffries, Suzan, Santhakumaran, S., Uthaya, S.N., Durighel, G., Alavi, Afshin, Modi, N., Thomas, E.L., Logan, Karen M., Parkinson, J.R.C. and Bell, J.D. 2015. Sexual dimorphism in relation to adipose tissue and intrahepatocellular lipid deposition in early infancy. International Journal of Obesity. 39 (4), pp. 629-32.

Molecularly imprinted polymer based on MWCNTs-QDs as fluorescent biomimetic sensor for specific recognition of target protein
Ding, X., Tao, L., Quan, J., Nie, H., Gong, X., Bligh, S.W.A. and Limin, Z. 2015. Molecularly imprinted polymer based on MWCNTs-QDs as fluorescent biomimetic sensor for specific recognition of target protein. Materials Science and Engineering C. 48, pp. 469-479.

Preterm nutritional intake and MRI phenotype at term age: a prospective observational study
Vasu, V., Durighel, G., Malamateniou, C., Rutherford, M.A., Modi, N., Thomas, E.L. and Bell, J.D. 2014. Preterm nutritional intake and MRI phenotype at term age: a prospective observational study. BMJ Open. 4 (5).

Body Fat: our own Janus
Thomas, E.L. and Bell, J.D. 2014. Body Fat: our own Janus. Physiology News. 96, pp. 24-27.

Multimetallic complexes and functionalized gold nanoparticles based on a combination of d- and f-elements
Sung, S., Holmes, H., Wainwright, L., Toscani, A., Stasiuk, G.J., White, A.J.P., Bell, J.D. and Wilton-Ely, J.D.E.T. 2014. Multimetallic complexes and functionalized gold nanoparticles based on a combination of d- and f-elements. Inorganic Chemistry. 53 (4), pp. 1989-2005.

Lectin recognizing thermoresponsive double hydrophilic glycopolymer micelles by RAFT polymerization
Sun, K., Bligh, S.W.A., Nie, H.L., Quan, J. and Zhu, L.M. 2014. Lectin recognizing thermoresponsive double hydrophilic glycopolymer micelles by RAFT polymerization. RSC Advances. 4, pp. 34912-34921.

The association between objectively measured sitting and standing with body composition: a pilot study using magnetic resonance imaging
Smith, L., Thomas, E.L., Bell, J.D. and Hamer, M. 2014. The association between objectively measured sitting and standing with body composition: a pilot study using magnetic resonance imaging. BMJ Open. 4 (6), p. e005476.

The intelligence paradox; will ET get the metabolic syndrome? Lessons from and for Earth
Nunn, A.V.W., Guy, G.W. and Bell, J.D. 2014. The intelligence paradox; will ET get the metabolic syndrome? Lessons from and for Earth. Nutrition and Metabolism. 11, p. 34.

A RG-II type polysaccharide purified from Aconitum coreanum and their anti-inflammatory activity
Li Xiaojun, Jiang Jiaye, Shi, S.S., Li Yuan, Jiang Yongbo, Huang Dan Ke Yan, Wang, S.C., Bligh, S.W.A. and Ke, Yan 2014. A RG-II type polysaccharide purified from Aconitum coreanum and their anti-inflammatory activity. PLoS ONE. 9 (6), p. e99697.

External validation of the fatty liver index and lipid accumulation product indices, using 1H-magnetic resonance spectroscopy, to identify hepatic steatosis in healthy controls and obese, insulin-resistant individuals
Cuthbertson, D.J., Weickert, M.O., Lythgoe, D., Sprung, V.S., Dobson, R., Shoajee-Moradie Fariba, Umpleby, A.M., Pfeiffer, A.F.H., Thomas, E.L., Bell, J.D., Jones, H. and Kemp, G.J. 2014. External validation of the fatty liver index and lipid accumulation product indices, using 1H-magnetic resonance spectroscopy, to identify hepatic steatosis in healthy controls and obese, insulin-resistant individuals. European Journal of Endocrinology. 171 (5), pp. 561-569.

Efficacy of increased resistant starch consumption in human type 2 diabetes
Bodinham, C.L., Smith, L., Thomas, E.L., Bell, J.D., Swann Jonathan, Costabile, A., Russell-Jones, D., Umpleby, A.M. and Robertson, M.D. 2014. Efficacy of increased resistant starch consumption in human type 2 diabetes. Endocrine Connections. 3 (2), pp. 75-84.

Quinolone alkaloids from fructus euodiae show activity against methicillin-resistant staphylococcus aureus
Pan, X., Bligh, S.W.A. and Smith, E. 2014. Quinolone alkaloids from fructus euodiae show activity against methicillin-resistant staphylococcus aureus. Phytotherapy Research. 28 (2), pp. 305-307.

Metabolic profiles of 20(S)-protopanaxadiol in rats after oral administration using ultra-performance liquid chromatography/quadrupole time-of-flight tandem mass spectrometry
He, C., Li, J., Wang, R., Li, Z., Bligh, S.W.A., Yang, L. and Wang, Z. 2014. Metabolic profiles of 20(S)-protopanaxadiol in rats after oral administration using ultra-performance liquid chromatography/quadrupole time-of-flight tandem mass spectrometry. Rapid Communications in Mass Spectrometry. 28 (6), pp. 595-604.

The short-chain fatty acid acetate reduces appetite via a central homeostatic mechanism
Frost, G.S., Sahuri-Arisoylu Meliz, Lizarbe Blanca, Cerdan Sebastian, Brody Leigh, Anastasovska, J., Ghourab Samar, Hankir, M., Zhang Shuai, Carling David Swann Jonathan, R., Gibson, G.R., Viardot, A., Morrison Douglas Thomas E Louise, Bell, J.D., Sleeth Michelle, L., Swann Jonathan and Thomas, E.L. 2014. The short-chain fatty acid acetate reduces appetite via a central homeostatic mechanism. Nature Communications. 5.

Adiposity and hepatic lipid in healthy full-term, breastfed, and formula-fed human infants: a prospective short-term longitudinal cohort study
Gale, C., Thomas, E.L., Jeffries, Suzan, Durighel, G., Logan, Karen M., Parkinson, J.R.C., Uthaya, S.N., Santhakumaran, S., Bell, J.D. and Modi, N. 2014. Adiposity and hepatic lipid in healthy full-term, breastfed, and formula-fed human infants: a prospective short-term longitudinal cohort study. American Journal of Clinical Nutition. 99 (5), pp. 1034-1040.

Structure of a homofructosan from Saussurea costus and anti-complementary activity of its sulfated derivatives
Fan, H., Liu, F., Bligh, S.W.A., Shi, S.S. and Wang, S.C. 2014. Structure of a homofructosan from Saussurea costus and anti-complementary activity of its sulfated derivatives. Carbohydrate Polymers. 105, pp. 152-160.

Characterization of two immunomodulating homogalacturonan pectins from green tea
Wang, H., Wei, G., Liu, F., Banerjee, G., Joshi, M., Bligh, S.W.A., Shi, S.S., Lian, H., Fan, H., Gu, X. and Wang, S.C. 2014. Characterization of two immunomodulating homogalacturonan pectins from green tea. International Journal of Molecular Sciences. 15 (6), pp. 9963-9978.

Obese patients after gastric bypass surgery have lower brain-hedonic responses to food than after gastric banding
Scholtz, S., Miras, A.D., Chhina, N., Prechtl, C.G., Sleeth Michelle, L., Daud Norlida, M., Ismail Nurhafzan, Durighel, G., Ahmed, A.R., Olbers, T., Vincent, R.P., Alaghband-Zadeh, J., Ghatei, M.A., Waldman, A.D., Frost, G.S., Bell, J.D., le Roux, C.W. and Goldstone, A.P. 2014. Obese patients after gastric bypass surgery have lower brain-hedonic responses to food than after gastric banding. Gut. 63 (6), pp. 891-902.

Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: rationale and design of the epidemiological studies within the IMI DIRECT Consortium
Koivula, R.W., Heggie, A., Barnett, A., Cederberg, H., Hansen, T.H., Koopman, A.D., Ridderstråle, M., Rutters, F., Vestergaard, H., Gupta, R., Herrgård, S., Heymans, M.W., Perry, M.H., Rauh, S., Siloaho, M., Teare, H.J.A., Thorand, B., Bell, J.D., Brunak, S., Frost, G.S., Jablonka, B., Mari, A., McDonald, T.J., Dekker, J.M., Hansen, T., Hattersley, A., Laakso, M., Pedersen, O., Koivisto, V., Ruetten, H., Walker, M., Pearson, E. and Franks, P.W. 2014. Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: rationale and design of the epidemiological studies within the IMI DIRECT Consortium. Diabetologia. 57 (6), pp. 1132-1142.

Ghrelin mimics fasting to enhance human hedonic, orbitofrontal cortex, and hippocampal responses to food
Goldstone, A.P., Prechtl, C.G., Scholtz, S., Miras, A.D., Chhina, N., Durighel, G., Deliran, S.S., Beckmann, C., Ghatei, M.A., Ashby, D.R., Waldman, A.D., Gaylinn, B.D., Thorner, M.O., Frost, G.S., Bloom, S.R. and Bell, J.D. 2014. Ghrelin mimics fasting to enhance human hedonic, orbitofrontal cortex, and hippocampal responses to food. American Journal of Clinical Nutition. 99 (6), pp. 1319-1330.

The impact of oligofructose on stimulation of gut hormones, appetite regulation and adiposity
Daud Norlida, M., Ismail Nurhafzan, Thomas, E.L., Fitzpatrick, J., Swann Jonathan, Costabile, A., Pedersen, C., Frost, G.S., Bell, J.D., Childs, C.E. and Goldstone, A.P. 2014. The impact of oligofructose on stimulation of gut hormones, appetite regulation and adiposity. Obesity (Silver Spring). 22 (6), pp. 1430-1438.

Electrosprayed core-shell nanoparticles of PVP and shellac for furnishing biphasic controlled release of ferulic acid
Cui, L., Liu, Z., Yu, D.G., Zhang, S.P., Bligh, S.W.A. and Zhao, N. 2014. Electrosprayed core-shell nanoparticles of PVP and shellac for furnishing biphasic controlled release of ferulic acid. Colloid and Polymer Science. 292 (9), pp. 2089-2096.

Synthesis, characterization and antiproliferative activity of hexa arm star shaped thiosemicarbazones derived from cyclotriphosphazene core
Machakanur, S.S., Patil, B.R., Naik, G.N., Bakale, R.P., Bligh, S.W.A. and Gudasi, K.B. 2014. Synthesis, characterization and antiproliferative activity of hexa arm star shaped thiosemicarbazones derived from cyclotriphosphazene core. Inorganica Chimica Acta. 421, pp. 459-464.

Characterization of metabolites of sweroside in rat urine using ultra-high-performance liquid chromatography combined with electrospray ionization quadrupole time-of-flight tandem mass spectrometry and NMR spectroscopy
Han, H., Zeng, W., He, C., Bligh, S.W.A., Liu, Q., Yang, L. and Wang, Z. 2014. Characterization of metabolites of sweroside in rat urine using ultra-high-performance liquid chromatography combined with electrospray ionization quadrupole time-of-flight tandem mass spectrometry and NMR spectroscopy. Journal of Mass Spectrometry. 49 (11), pp. 1108-1116.

A history of previous gestational diabetes mellitus is associated with adverse changes in insulin secretion and VLDL metabolism independently of increased intrahepatocellular lipid
Forbes, S., Godsland, I.F., Taylor-Robinson, S.D., Bell, J.D., Thomas, E.L., Patel, N., Hamilton, G., Parker, K.H., Marshall, I., Gray, C.D., Bedford, D.C., Caslake, M., Walker, B.R. and Johnston, D.G. 2013. A history of previous gestational diabetes mellitus is associated with adverse changes in insulin secretion and VLDL metabolism independently of increased intrahepatocellular lipid. Diabetologia. 56 (9), pp. 2021-2033.

Whole body fat: content and distribution
Thomas, E.L., Fitzpatrick, J., Malik, S.J., Taylor-Robinson, S.D. and Bell, J.D. 2013. Whole body fat: content and distribution. Progress in Nuclear Magnetic Resonance Spectroscopy. 73, pp. 56-80.

Enhanced replication of R5 HIV-1 isolates in vitro by a small-molecule reagent targeting HIV-1 protease
Wardle, N.J., Hudson, H.R., Matthews, R.W., Nunn, C., Vella, C. and Bligh, S.W.A. 2013. Enhanced replication of R5 HIV-1 isolates in vitro by a small-molecule reagent targeting HIV-1 protease. ChemMedChem. 8 (5), pp. 719-721.

Dual drug release nanocomposites prepared using a combination of electrospraying and electrospinning
Yu, D.G., Williams, G.R., Wang, X., Liu, X.-K., Li, H.L. and Bligh, S.W.A. 2013. Dual drug release nanocomposites prepared using a combination of electrospraying and electrospinning. RSC Advances. OnlineFirst.

Coaxial electrospinning using a concentric Teflon spinneret to prepare biphasic-release nanofibers of helicid
Yu, D.G., Liu, F., Cui, L., Liu, Z., Wang, X. and Bligh, S.W.A. 2013. Coaxial electrospinning using a concentric Teflon spinneret to prepare biphasic-release nanofibers of helicid. RSC Advances. OnlineFirst.

Early nutritional determinants of intrahepatocellular lipid deposition in preterm infants at term age
Vasu, V., Thomas, E.L., Durighel, G., Hyde, M.J., Bell, J.D. and Modi, N. 2013. Early nutritional determinants of intrahepatocellular lipid deposition in preterm infants at term age. International Journal of Obesity. 37 (4), pp. 500-504.

Metabolic syndrome, overweight and fatty liver
Thomas, E.L., Fitzpatrick, J., Frost, G.S. and Bell, J.D. 2013. Metabolic syndrome, overweight and fatty liver. in: Berdanier, C.D., Dwyer, J.T. and Heber, D. (ed.) Handbook of nutrition and food, 3rd edition Boca Raton CRC Press. pp. 763-768

Sensitized terbium(III) macrocyclic-phthalimide complexes as luminescent pH switches
Chen, G., Wardle, N.J., Sarris, J.L., Chatterton, N.P. and Bligh, S.W.A. 2013. Sensitized terbium(III) macrocyclic-phthalimide complexes as luminescent pH switches. Dalton Transactions. OnlineFirst.

Flavonoids by HPLC
Bligh, S.W.A., Ogegbo, O. and Wang, Z. 2013. Flavonoids by HPLC. in: Ramawat, K.G. and Merillon, J.M. (ed.) Natural products: phytochemistry, botany and metabolism of alkaloids, phenolics and terpenes Berlin Springer. pp. 2107-2144

Mutations in the GABRB1 gene promote alcohol consumption through increased tonic inhibition
Anstee, Q.M., Knapp, S., Maguire, E.P., Hosie, A.M., Thomas, P., Mortensen, M., Bhome, R., Martinez, A., Walker, S.E., Dixon, C.I., Ruparelia, K., Montagnese, S., Kuo, Y.T., Herlihy, A.H., Bell, J.D., Robinson, I., Guerrini, I., McQuillin, A., Fisher, E.M.C., Ungless, M.A., Gurling, H.M.D., Morgan, M.Y., Brown, S.D.M., Stephens, D.N., Belelli, D., Lambert, J.J., Smart, T.G. and Thomas, H.C. 2013. Mutations in the GABRB1 gene promote alcohol consumption through increased tonic inhibition. Nature Communications. 4, p. 2816.

Endocannabinoids in neuroendopsychology: multiphasic control of mitochondrial function
Nunn, A.V.W., Guy, G.W. and Bell, J.D. 2012. Endocannabinoids in neuroendopsychology: multiphasic control of mitochondrial function. Philosophical Transactions of the Royal Society B: Biological Sciences. 367 (1607), pp. 3342-3352.

Adiposity in children and adolescents: correlates and clinical consequences of fat stored in specific body depots
Katzmarzyk, P.T., Shen, W., Baxter-Jones, A., Bell, J.D., Butte, N.F., Demerath, E.W., Gilsanz, V., Goran, M.I., Hirschler, V., Hu, H.H., Maffeis, C., Malina, R.M., Müller, M.J., Pietrobelli, A. and Wells, J.C.K. 2012. Adiposity in children and adolescents: correlates and clinical consequences of fat stored in specific body depots. Pediatric Obesity. 7 (5), pp. e42-e61.

Polycystic ovary syndrome with hyperandrogenism is characterized by an increased risk of hepatic steatosis compared to nonhyperandrogenic PCOS phenotypes and healthy controls, independent of obesity and insulin resistance
Jones, H., Sprung, V.S., Pugh, C.J.A., Daousi, C., Irwin, A., Aziz, N., Adams, V.L., Thomas, E.L., Bell, J.D., Kemp, G.J. and Cuthbertson, D.J. 2012. Polycystic ovary syndrome with hyperandrogenism is characterized by an increased risk of hepatic steatosis compared to nonhyperandrogenic PCOS phenotypes and healthy controls, independent of obesity and insulin resistance. Journal of Clinical Endocrinology and Metabolism. 97 (10), pp. 3709-3716.

Effect of lactobacillus acidophilus NCDC 13 supplementation on the progression of obesity in diet-induced obese mice
Arora, T., Anastasovska, J., Gibson, G.R., Tuohy, K., Kumar Sharma, R., Bell, J.D. and Frost, G.S. 2012. Effect of lactobacillus acidophilus NCDC 13 supplementation on the progression of obesity in diet-induced obese mice. British Journal of Nutrition. 108 (8), pp. 1382-1389.

Metabolic pathways of the psychotropic-carboline alkaloids, harmaline and harmine, by liquid chromatography/mass spectrometry and NMR spectroscopy
Zhao, T., Zheng, S.S., Zhang, B.F., Li, Y.Y., Bligh, S.W.A., Wang, C.-H. and Wang, Z. 2012. Metabolic pathways of the psychotropic-carboline alkaloids, harmaline and harmine, by liquid chromatography/mass spectrometry and NMR spectroscopy. Food Chemistry. 134 (2), pp. 1096-1105.

Fatty acid flux and oxidation are increased by rimonabant in obese women
Backhouse, K., Sarac, I., Shojaee-Moradie, F., Stolinski, M., Robertson, M.D., Frost, G.S., Bell, J.D., Thomas, E.L., Wright, J., Russell-Jones, D. and Umpleby, A.M. 2012. Fatty acid flux and oxidation are increased by rimonabant in obese women. Metabolism: Clinical and Experimental. 61 (9), pp. 1220-1223.

Chemotaxonomically significant roburic acid from section cruciata of gentiana
Wu, L.H., Bligh, S.W.A., Leon, C., Li, X.S., Wang, Z., Branford-White, C.J. and Simmonds, M.S.J. 2012. Chemotaxonomically significant roburic acid from section cruciata of gentiana. Biochemical Systematics and Ecology. 43, pp. 152-155.

Gender differences in VLDL1 and VLDL2 triglyceride kinetics and fatty acid kinetics in obese postmenopausal women and obese men
Sarac, I., Backhouse, K., Shojaee-Moradie, F., Stolinski, M., Robertson, M.D., Bell, J.D., Thomas, E.L., Hovorka, R., Wright, J. and Umpleby, A.M. 2012. Gender differences in VLDL1 and VLDL2 triglyceride kinetics and fatty acid kinetics in obese postmenopausal women and obese men. Journal of Clinical Endocrinology and Metabolism. 97 (7), pp. 2475-2481.

Excess body fat in obese and normal weight subjects
Thomas, E.L., Frost, G.S., Taylor-Robinson, S.D. and Bell, J.D. 2012. Excess body fat in obese and normal weight subjects. Nutrition Research Reviews. 25 (1), pp. 150-161.

The effect of preterm birth on adiposity and metabolic pathways and the implications for later life
Thomas, E.L., Al Saud, N.B., Durighel, G., Frost, G.S. and Bell, J.D. 2012. The effect of preterm birth on adiposity and metabolic pathways and the implications for later life. Clinical Lipidology. 7 (3), pp. 275-288.

Elemental imaging of MRI contrast agents: benchmarking of LA-ICP-MS to MRI
Pugh, J.A.T., Cox, A.G., McLeod, C.W., Bunch, J., Writer, M.J., Hart, S.L., Bienemann, A., White, E. and Bell, J.D. 2012. Elemental imaging of MRI contrast agents: benchmarking of LA-ICP-MS to MRI. Analytical and bioanalytical chemistry. 403 (6), pp. 1641-1649.

Intrahepatic insulin exposure, intrahepatocellular lipid and regional body fat in non-alcoholic fatty liver disease
Mehta, S.R., Godsland, I.F., Thomas, E.L., Pavitt, D.V., Morin, S.H.X., Bell, J.D., Taylor-Robinson, S.D. and Johnston, D.G. 2012. Intrahepatic insulin exposure, intrahepatocellular lipid and regional body fat in non-alcoholic fatty liver disease. Journal of Clinical Endocrinology and Metabolism. 97 (6), pp. 2151-2159.

Hepatic steatosis, GH deficiency and the effects of GH replacement: a Liverpool magnetic resonance spectroscopy study
Gardner, C.J., Irwin, A., Daousi, C., McFarlane, I.A., Joseph, F., Bell, J.D., Thomas, E.L., Adams, V.L., Kemp, G.J. and Cuthbertson, D.J. 2012. Hepatic steatosis, GH deficiency and the effects of GH replacement: a Liverpool magnetic resonance spectroscopy study. European Journal of Endocrinology. 166, pp. 993-1002.

Bioactivity-guided fractionation of the volatile oil of Angelica sinensis radix designed to preserve the synergistic effects of the mixture followed by identification of the active principles
Yeh, J.C., Garrard, I.J., Cho, C.W.C., Bligh, S.W.A., Lu, G.H., Fan, T.P. and Fisher, D. 2012. Bioactivity-guided fractionation of the volatile oil of Angelica sinensis radix designed to preserve the synergistic effects of the mixture followed by identification of the active principles. Journal of Chromatography A. 1236, pp. 132-138.

Simultaneous determination of six alkaloids and one monoterpene in rat plasma by liquid chromatography–tandem mass spectrometry and pharmacokinetic study after oral administration of a Chinese medicine Wuji Pill
Yuan, J., Wang, Y., An, R., Wang, S., Li, S.J., Jia, J.Y., Bligh, S.W.A., Wang, X.H. and Ma, Y.M. 2012. Simultaneous determination of six alkaloids and one monoterpene in rat plasma by liquid chromatography–tandem mass spectrometry and pharmacokinetic study after oral administration of a Chinese medicine Wuji Pill. Journal of Chromatography B: Biomedical Sciences and Applications. 895-896, pp. 154-161.

Evodiamine, a dual catalytic inhibitor of type I and II topoisomerases, exhibits enhanced inhibition against camptothecin resistant cells
Pan, X., Hartley, J.M., Hartley, J.A., White, K.N., Wang, Z. and Bligh, S.W.A. 2012. Evodiamine, a dual catalytic inhibitor of type I and II topoisomerases, exhibits enhanced inhibition against camptothecin resistant cells. Phytomedicine. 19 (7), pp. 618-624.

Fermentable carbohydrate alters hypothalamic neuronal activity and protects against the obesogenic environment
Anastasovska, J., Arora, T., Sanchez-Canon, G.J., Parkinson, J.R.C., Touhy, K., Gibson, G.R., Nadkarni, N., So, P.W., Goldstone, A.P., Thomas, E.L., Hankir, M., Van Loo, J., Modi, N., Bell, J.D. and Frost, G.S. 2012. Fermentable carbohydrate alters hypothalamic neuronal activity and protects against the obesogenic environment. Obesity. 20 (5), pp. 1016-1023.

Synthesis, characterization and anticancer evaluation of novel tri-arm star shaped 1,3,5-triazine hydrazones
Machakanur, S.S., Patil, B.R., Badiger, D.S., Bakale, R.P., Gudasi, K.B. and Bligh, S.W.A. 2012. Synthesis, characterization and anticancer evaluation of novel tri-arm star shaped 1,3,5-triazine hydrazones. Journal of Molecular Structure. 1011, pp. 121-127.

Coaxial electrospinning with sodium dodecylbenzene sulfonate solution for high quality polyacrylonitrile nanofibers
Yu, D.G., Williams, G.R., Gao, L.D., Bligh, S.W.A., Yang, J.-H. and Wang, X. 2012. Coaxial electrospinning with sodium dodecylbenzene sulfonate solution for high quality polyacrylonitrile nanofibers. Colloids and Surfaces A: Physicochemical and Engineering Aspects. 396, pp. 161-168.

Validation of dual energy x-ray absorptiometry measures of abdominal fat by comparison with magnetic resonance imaging in an Indian population
Taylor, A.E., Kuper, H., Varma, R.D., Wells, J.C.K., Bell, J.D., Radhakrishna, K.V., Kulkarni, B., Kinra, S., Timpson, N.J., Ebrahim, S., Smith, G.D. and Ben-Shlomo, Y. 2012. Validation of dual energy x-ray absorptiometry measures of abdominal fat by comparison with magnetic resonance imaging in an Indian population. PLoS ONE. 7 (12), p. e51042.

Metabolic profiling of the rat liver after chronic ingestion of alpha-naphthylisothiocyanate using in vivo and ex vivo magnetic resonance spectroscopy
Solanky, B.S., Sanchez-Canon, G.J., Cobbold, J.F.L., Taylor-Robinson, S.D., Bell, J.D., Scudamore, C.L., Ross, E., Holder, J.C., So, P.W. and Cox, I.J. 2012. Metabolic profiling of the rat liver after chronic ingestion of alpha-naphthylisothiocyanate using in vivo and ex vivo magnetic resonance spectroscopy. Toxicological Sciences. 126 (2), pp. 306-316.

Metabolomics of four TCM herbal products: application of HPTLC analysis
Ogegbo, O., Eyob, S., Parmar, S., Wang, Z. and Bligh, S.W.A. 2012. Metabolomics of four TCM herbal products: application of HPTLC analysis. Analytical Methods. 4, pp. 2522-2527.

Synthesis of novel tri-arm star shaped 1,3,5-triazine hydrazones from 2,4,6-tris(4-acetylphenoxy)-1,3,5-triazine core
Machakanur, S.S., Patil, B.R., Badiger, D.S., Pathan, A.H., Gudasi, K.B. and Bligh, S.W.A. 2012. Synthesis of novel tri-arm star shaped 1,3,5-triazine hydrazones from 2,4,6-tris(4-acetylphenoxy)-1,3,5-triazine core. Letters in Organic Chemistry. 9 (1), pp. 29-34.

N-Heterocyclic dronic acids: applications and synthesis
Hudson, H.R., Wardle, N.J., Bligh, S.W.A., Greiner, I., Grun, A. and Keglevich, G. 2012. N-Heterocyclic dronic acids: applications and synthesis. Minireviews in Medicinal Chemistry. 12, pp. 313-325.

Increased energy expenditure in gastric bypass rats is not caused by activated brown adipose tissue
Hankir, M., Bueter, M., Gsell, W., Seyfried, F., Khalil, M., Smith, K.L., Bloom, S.R., Bell, J.D. and le Roux, C.W. 2012. Increased energy expenditure in gastric bypass rats is not caused by activated brown adipose tissue. Obesity Facts. 5 (3), pp. 349-358.

Quantification of norisoboldine in Linderae Radix by ultra-performance liquid chromatography and high performance liquid chromatography with UV detection
Chen, J.Z., Chou, G.-X., Yang, L., Bligh, S.W.A. and Wang, Z. 2012. Quantification of norisoboldine in Linderae Radix by ultra-performance liquid chromatography and high performance liquid chromatography with UV detection. Journal of Liquid Chromatography and Related Technologies. 35 (6), pp. 788-797.

A chemically unlocked binary molecular switch
Chen, G., Sarris, J.L., Wardle, N.J., Bligh, S.W.A. and Chatterton, N.P. 2012. A chemically unlocked binary molecular switch. Chemical Communications. 48 (72), pp. 9026-9028.

Relation between trunk fat volume and reduction of total lung capacity in obese men
Watson, R.A., Pride, N.B., Thomas, E.L., Ind, P.W. and Bell, J.D. 2012. Relation between trunk fat volume and reduction of total lung capacity in obese men. Journal of Applied Physiology. 112 (1), pp. 118-126.

The missing risk: MRI and MRS phenotyping of abdominal adiposity and ectopic fat
Thomas, E.L., Parkinson, J.R.C., Frost, G.S., Goldstone, A.P., Doré, C.J., McCarthy, J., Collins, A.L., Fitzpatrick, J., Durighel, G., Taylor-Robinson, S.D. and Bell, J.D. 2012. The missing risk: MRI and MRS phenotyping of abdominal adiposity and ectopic fat. Obesity. 20 (1), pp. 76-87.

Urinary 1H-NMR metabonomics study on intervention effects of soya milk in Africans
Ogegbo, O., Dissanyake, W., Crowder, J., Asekun, O., Familoni, O., Branford-White, C.J. and Bligh, S.W.A. 2012. Urinary 1H-NMR metabonomics study on intervention effects of soya milk in Africans. Phytotherapy Research. 26 (1), pp. 127-135.

The effects of glutamate receptor agonists and antagonists on mouse hypothalamic and hippocampal neuronal activity shown through manganese enhanced MRI
Hankir, M., Parkinson, J.R.C., Bloom, S.R. and Bell, J.D. 2012. The effects of glutamate receptor agonists and antagonists on mouse hypothalamic and hippocampal neuronal activity shown through manganese enhanced MRI. NeuroImage. 59 (2), pp. 968-978.

Debrisoquine metabolism and CYP2D expression in marmoset liver microsomes
Cooke, B.R., Bligh, S.W.A., Cybulski, Z.R., Ioannides, C. and Hall, M. 2012. Debrisoquine metabolism and CYP2D expression in marmoset liver microsomes. Drug Metabolism and Disposition. 40 (1), pp. 70-75.

Identification of metabolites of geniposide in rat urine using ultra-performance liquid chromatography combined with electrospray ionization quadrupole time-of-flight tandem mass spectrometry
Han, H., Yang, L., Xu, Y., Ding, Y., Bligh, S.W.A., Zhang, T. and Wang, Z. 2011. Identification of metabolites of geniposide in rat urine using ultra-performance liquid chromatography combined with electrospray ionization quadrupole time-of-flight tandem mass spectrometry. Rapid Communications in Mass Spectrometry. 25 (21), pp. 3339-3350.

1H NMR study of monocrotaline and its metabolites in human blood
Yang, Y.C., Crowder, J., Wardle, N.J., Yang, L., White, K.N., Wang, Z. and Bligh, S.W.A. 2011. 1H NMR study of monocrotaline and its metabolites in human blood. Food and Chemical Toxicology. 49 (11), pp. 2793-2799.

Hexa-arm star shaped hydrazone derivatives from hexakis(4-formylphenoxy)-cyclotriphosphazene core
Patil, B.R., Machakanur, S.S., Badiger, D.S., Hunoor, R.S., Gudasi, K.B., Nethaji, M. and Bligh, S.W.A. 2011. Hexa-arm star shaped hydrazone derivatives from hexakis(4-formylphenoxy)-cyclotriphosphazene core. Journal of Molecular Structure. 1003 (1-3), pp. 52-61.

A low molecular weight folate receptor targeted contrast agent for magnetic resonance tumour imaging
Kalber, T., Kamaly, N., So, P.W., Pugh, J.A.T., Bunch, J., McLeod, C.W., Jorgensen, M.R., Miller, A.D. and Bell, J.D. 2011. A low molecular weight folate receptor targeted contrast agent for magnetic resonance tumour imaging. Molecular Imaging and Biology. 13 (4), pp. 653-662.

Synthesis and characterisation of a novel tubulin-directed DO3A–colchicine conjugate with potential theranostic features
Wardle, N.J., Kalber, T., Bell, J.D. and Bligh, S.W.A. 2011. Synthesis and characterisation of a novel tubulin-directed DO3A–colchicine conjugate with potential theranostic features. Bioorganic and Medicinal Chemistry Letters. 21 (11), pp. 3346-3348.

Improving polymer nanofiber quality using a modified co-axial electrospinning process
Yu, D.G., Branford-White, C.J., Bligh, S.W.A., White, K.N., Chatterton, N.P. and Zhu, L.M. 2011. Improving polymer nanofiber quality using a modified co-axial electrospinning process. Macromolecular Rapid Communications. 32 (9-10), pp. 744-750.

Peptide YY3-36 and pancreatic polypeptide differentially regulate hypothalamic neuronal activity in mice in vivo as measured by manganese-enhanced magnetic resonance imaging
Hankir, M., Parkinson, J.R.C., Minnion, J.S., Addison, M.L., Bloom, S.R. and Bell, J.D. 2011. Peptide YY3-36 and pancreatic polypeptide differentially regulate hypothalamic neuronal activity in mice in vivo as measured by manganese-enhanced magnetic resonance imaging. Journal of Neuroendocrinology. 23 (4), pp. 371-380.

Novel multifunctional nanoparticle mediates siRNA tumour delivery, visualisation and therapeutic tumour reduction in vivo
Kenny, G., Kamaly, N., Kalber, T., Brody Leigh, Sahuri-Arisoylu Meliz, Shamsaei, E., Miller, A.D. and Bell, J.D. 2011. Novel multifunctional nanoparticle mediates siRNA tumour delivery, visualisation and therapeutic tumour reduction in vivo. Journal of Controlled Release. 149 (2), pp. 111-116.

Coaxial electrospinning with organic solvent for controlling the size of self-assembled nanoparticles
Yu, D.G., Zhu, L.M., Bligh, S.W.A., Branford-White, C.J. and White, K.N. 2011. Coaxial electrospinning with organic solvent for controlling the size of self-assembled nanoparticles. Chemical Communications. 47 (4), pp. 1216-1218.

Self-assembled liposomes from amphiphilic electrospun nanofibers
Yu, D.G., Branford-White, C.J., Williams, G.R., Bligh, S.W.A., White, K.N., Zhu, L.M. and Chatterton, N.P. 2011. Self-assembled liposomes from amphiphilic electrospun nanofibers. Soft matter. 7, pp. 8239-8247.

Aberrant adiposity and ectopic lipid deposition characterize the adult phenotype of the preterm infant
Thomas, E.L., Parkinson, J.R.C., Hyde, M.J., Yap, I.K.S., Holmes, E., Doré, C.J., Bell, J.D. and Modi, N. 2011. Aberrant adiposity and ectopic lipid deposition characterize the adult phenotype of the preterm infant. Paediatric Research. 70 (5), pp. 507-512.

Pragmatic study of orlistat 60 mg on abdominal obesity
Thomas, E.L., Makwana, A., Newbould, R., Rao, A.W., Gambarota, G., Frost, G.S., Delafont, B., Mishra, R.G., Matthews, P.M., Berk, E.S., Schwartz, S.M., Bell, J.D. and Beaver, J.D. 2011. Pragmatic study of orlistat 60 mg on abdominal obesity. European Journal of Clinical Nutrition. 65, pp. 1256-1262.

Targeting of anionic membrane species by lanthanide(III) complexes: towards improved MRI contrast agents for apoptosis
Surman, A.J., Kenny, G., Krishna Kumar, D., Bell, J.D., Casey, D.R. and Vilar, R. 2011. Targeting of anionic membrane species by lanthanide(III) complexes: towards improved MRI contrast agents for apoptosis. Chemical Communications. 47, pp. 10245-10247.

Synthesis and anti-cancer evaluation of cyclotriphosphazene hydrazone derivatives
Patil, B.R., Machakanur, S.S., Hunoor, R.S., Badiger, D.S., Gudasi, K.B. and Bligh, S.W.A. 2011. Synthesis and anti-cancer evaluation of cyclotriphosphazene hydrazone derivatives. Der Pharma Chemica. 3 (4), pp. 377-388.

The influence of maternal body mass index on infant adiposity and hepatic lipid content
Modi, N., Murgasova, D., Ruager-Martin, R., Thomas, E.L., Hyde, M.J., Gale, C., Santhakumaran, S., Doré, C.J., Alavi, Afshin and Bell, J.D. 2011. The influence of maternal body mass index on infant adiposity and hepatic lipid content. Paediatric Research. 70 (3), pp. 287-291.

Synthesis and characterization of a theranostic vascular disrupting agent for in vivo MR imaging
Kalber, T., Kamaly, N., Higham, S.A., Pugh, J.A.T., Bunch, J., McLeod, C.W., Miller, A.D. and Bell, J.D. 2011. Synthesis and characterization of a theranostic vascular disrupting agent for in vivo MR imaging. Bioconjugate Chemistry. 22 (5), pp. 879-886.

A pyrophosphate-responsive gadolinium(III) MRI contrast agent
Surman, A.J., Bonnet, C.S., Lowe, M.P., Kenny, G., Bell, J.D., Tóth, É. and Vilar, R. 2011. A pyrophosphate-responsive gadolinium(III) MRI contrast agent. Chemistry: A European Journal. 17 (1), pp. 223-230.

Manganese enhancement in non-CNS organs
Lee, L.W., So, P.W., Price, A.N., Parkinson, J.R.C., Larkman, D.J., Halliday, J., Poucher, S.M., Pugh, J.A.T., Cox, A.G., McLeod, C.W. and Bell, J.D. 2010. Manganese enhancement in non-CNS organs. NMR in Biomedicine. 23 (8), pp. 931-938.

Characterization of new metabolites from in vivo biotransformation of norisoboldine by liquid chromatography/mass spectrometry and NMR spectroscopy
Chen, J.Z., Chou, G.-X., Wang, C.-H., Yang, L., Bligh, S.W.A. and Wang, Z. 2010. Characterization of new metabolites from in vivo biotransformation of norisoboldine by liquid chromatography/mass spectrometry and NMR spectroscopy. Journal of Pharmaceutical and Biomedical Analysis. 52 (5), pp. 687-693.

Separation and identification of three epimeric pairs of new C-glucosyl anthrones from Rumex dentatus by on-line high performance liquid chromatography–circular dichroism analysis
Zhu, J.-J., Zhang, C.-F., Zhang, M., Bligh, S.W.A., Yang, L., Wang, Z.-M. and Wang, Z. 2010. Separation and identification of three epimeric pairs of new C-glucosyl anthrones from Rumex dentatus by on-line high performance liquid chromatography–circular dichroism analysis. Journal of Chromatography A. 1217 (33), pp. 5384-5388.

Endocannabinoids, FOXO and the metabolic syndrome: redox, function and tipping point – the view from two systems
Nunn, A.V.W., Guy, G.W. and Bell, J.D. 2010. Endocannabinoids, FOXO and the metabolic syndrome: redox, function and tipping point – the view from two systems. Immunobiology. 215 (8), pp. 617-628.

Imaging of gadolinium spatial distribution in tumor tissue by laser ablation inductively coupled plasma mass spectrometry
Kamaly, N., Pugh, J.A.T., Kalber, T., Bunch, J., Miller, A.D., McLeod, C.W. and Bell, J.D. 2010. Imaging of gadolinium spatial distribution in tumor tissue by laser ablation inductively coupled plasma mass spectrometry. Molecular Imaging and Biology. 12 (4), pp. 361-366.

Peripherally injected cholecystokinin-induced neuronal activation is modified by dietary composition in mice
Zeeni, N., Nadkarni, N., Bell, J.D., Even, P.C., Fromentin, G., Tome, D. and Darcel, N. 2010. Peripherally injected cholecystokinin-induced neuronal activation is modified by dietary composition in mice. NeuroImage. 50 (4), pp. 1560-1565.

The combined effects on neuronal activation and blood–brain barrier permeability of time and n-3 polyunsaturated fatty acids in mice, as measured in vivo using MEMRI
Kuo, Y.T., So, P.W., Parkinson, J.R.C., Yu, W.S., Hankir, M., Herlihy, A.H., Goldstone, A.P., Frost, G.S., Wasserfall, C. and Bell, J.D. 2010. The combined effects on neuronal activation and blood–brain barrier permeability of time and n-3 polyunsaturated fatty acids in mice, as measured in vivo using MEMRI. NeuroImage. 50 (4), pp. 1384-1391.

Proton magnetic resonance spectroscopy and ultrasound for hepatic fat quantification
Mehta, S.R., Thomas, E.L., Patel, N., Crofton, M.E., McCarthy, J., Eliahoo, J., Morin, S.H.X., Fitzpatrick, J., Durighel, G., Goldstone, A.P., Johnston, D.G., Bell, J.D. and Taylor-Robinson, S.D. 2010. Proton magnetic resonance spectroscopy and ultrasound for hepatic fat quantification. Hepatology Research. 40 (4), pp. 399-406.

Resistant starch improves insulin sensitivity in metabolic syndrome
Johnston, K.L., Thomas, E.L., Bell, J.D., Frost, G.S. and Robertson, M.D. 2010. Resistant starch improves insulin sensitivity in metabolic syndrome. Diabetic Medicine. 27 (4), pp. 391-397.

O-phosphotyrosine analogues: aynthesis and therapeutic role in modulation of signal transduction
Wardle, N.J., Hudson, H.R. and Bligh, S.W.A. 2010. O-phosphotyrosine analogues: aynthesis and therapeutic role in modulation of signal transduction. Current Organic Chemistry. 14 (5), pp. 426-446.

Reduction of total lung capacity in obese men: comparison of total intrathoracic and gas volumes
Watson, R.A., Pride, N.B., Thomas, E.L., Fitzpatrick, J., Durighel, G., McCarthy, J., Morin, S.H.X., Ind, P.W. and Bell, J.D. 2010. Reduction of total lung capacity in obese men: comparison of total intrathoracic and gas volumes. Journal of Applied Physiology. 108 (6), pp. 1605-1612.

Estimation of abdominal fat compartments by bioelectrical impedance: the validity of the ViScan measurement system in comparison with MRI
Thomas, E.L., Collins, A.L., McCarthy, J., Fitzpatrick, J., Durighel, G., Goldstone, A.P. and Bell, J.D. 2010. Estimation of abdominal fat compartments by bioelectrical impedance: the validity of the ViScan measurement system in comparison with MRI. European Journal of Clinical Nutrition. 64, pp. 525-533.

Efficient and rapid labelling of transplanted cell populations with superparamagnetic iron oxide nanoparticles using cell surface chemical biotinylation for in vivo monitoring by MRI
So, P.W., Kalber, T., Hunter, D., Farquharson, M., Al-Ebraheem, A., Parkes, H.G., Simon, R. and Bell, J.D. 2010. Efficient and rapid labelling of transplanted cell populations with superparamagnetic iron oxide nanoparticles using cell surface chemical biotinylation for in vivo monitoring by MRI. Cell Transplantation. 19 (4), pp. 419-429.

Inflammatory modulation of exercise salience: using hormesis to return to a healthy lifestyle
Nunn, A.V.W., Guy, G.W., Brodie, J.S. and Bell, J.D. 2010. Inflammatory modulation of exercise salience: using hormesis to return to a healthy lifestyle. Nutrition & Metabolism. 7, p. 87.

Chemistry of tumour targeted T1 based MRI contrast agents
Kamaly, N., Miller, A.D. and Bell, J.D. 2010. Chemistry of tumour targeted T1 based MRI contrast agents. Current Topics in Medicinal Chemistry. 10 (12), pp. 1158-1183.

A novel bimodal lipidic contrast agent for cellular labelling and tumour MRI
Kamaly, N., Kalber, T., Kenny, G., Bell, J.D., Jorgensen, M.R. and Miller, A.D. 2010. A novel bimodal lipidic contrast agent for cellular labelling and tumour MRI. Organic and Biomolecular Chemistry. 8, pp. 201-211.

Treatment with qing'e, a kidney-invigorating chinese herbal formula, antagonizes the estrogen decline in ovariectomized mice
Xu, Y., Zhang, Z.J., Geng, F., Su, S.B., White, K.N., Bligh, S.W.A., Branford-White, C.J. and Wang, Z. 2010. Treatment with qing'e, a kidney-invigorating chinese herbal formula, antagonizes the estrogen decline in ovariectomized mice. Rejuvenation Research. 13 (4), pp. 479-488.

Identification of metabolites of adonifoline, a hepatotoxic pyrrolizidine alkaloid, by liquid chromatography/tandem and high-resolution mass spectrometry
Xiong, A., Yang, L., He, Y.Q., Zhang, F., Wang, J., Han, H., Wang, C.-H., Bligh, S.W.A. and Wang, Z. 2009. Identification of metabolites of adonifoline, a hepatotoxic pyrrolizidine alkaloid, by liquid chromatography/tandem and high-resolution mass spectrometry. Rapid Communications in Mass Spectrometry. 23 (24), pp. 3907-3916.

Incidental findings in healthy control research subjects using whole-body MRI
Morin, S.H.X., Cobbold, J.F.L., Lim, A.K.P., Eliahoo, J., Thomas, E.L., Mehta, S.R., Durighel, G., Fitzpatrick, J., Bell, J.D. and Taylor-Robinson, S.D. 2009. Incidental findings in healthy control research subjects using whole-body MRI. European Journal of Radiology. 72 (3), pp. 529-533.

Dominant role of the p110β isoform of PI3K over p110α in energy homeostasis regulation by POMC and AgRP neurons
Al-Qassab, H., Smith, M.A., Irvine, E.E., Guillermet-Guibert, J., Claret, M., Choudhury, A.I., Selman, C., Piipari, K., Clements, M., Lingard, S., Chandarana, K., Bell, J.D., Barsh, G.S., Smith, A.J.H., Batterham, R.L., Ashford, M.L.J., Vanhaesebroeck, B. and Withers, D.J. 2009. Dominant role of the p110β isoform of PI3K over p110α in energy homeostasis regulation by POMC and AgRP neurons. Cell Metabolism. 10 (5), pp. 343-354.

Fasting biases brain reward systems towards high-calorie foods
Goldstone, A.P., Prechtl de Hernandez, C.G., Beaver, J.D., Muhammed, K., Croese, C., Bell, G., Durighel, G., Hughes, E., Waldman, A.D., Frost, G.S. and Bell, J.D. 2009. Fasting biases brain reward systems towards high-calorie foods. European Journal of Neuroscience. 30 (8), pp. 1625-1635.

Cerebral activation by fasting induces lactate accumulation in the hypothalamus
Violante, I.R., Anastasovska, J., Sanchez-Canon, G.J., Rodrigues, T.B., Righi, V., Nieto-Charques, L., Parkinson, J.R.C., Bloom, S.R., Bell, J.D. and Cerdan Sebastian 2009. Cerebral activation by fasting induces lactate accumulation in the hypothalamus. Magnetic Resonance in Medicine. 62 (2), pp. 279-283.

Obesity, diabetes and longevity in the Gulf: is there a Gulf metabolic syndrome?
Guy, G.W., Nunn, A.V.W., Thomas, E.L. and Bell, J.D. 2009. Obesity, diabetes and longevity in the Gulf: is there a Gulf metabolic syndrome? International Journal of Diabetes Mellitus. 1 (1), pp. 43-54.

Comprehensive two-dimensional high-performance liquid chromatography system with immobilized liposome chromatography column and reversed-phase column for separation of complex traditional Chinese medicine Longdan Xiegan Decoction
Wang, Y., Kong, L., Lei, X., Hu, L., Zou, H., Welbeck, E., Bligh, S.W.A. and Wang, Z. 2009. Comprehensive two-dimensional high-performance liquid chromatography system with immobilized liposome chromatography column and reversed-phase column for separation of complex traditional Chinese medicine Longdan Xiegan Decoction. Journal of Chromatography A. 1216 (11), pp. 2185-2191.

Differential patterns of neuronal activation in the brainstem and hypothalamus following peripheral injection of GLP-1, oxyntomodulin and lithium chloride in mice detected by manganese-enhanced magnetic resonance imaging (MEMRI)
Parkinson, J.R.C., Chaudhri, O.B., Kuo, Y.T., Field, B.C.T., Herlihy, A.H., Dhillo, W.S., Ghatei, M.A., Bloom, S.R. and Bell, J.D. 2009. Differential patterns of neuronal activation in the brainstem and hypothalamus following peripheral injection of GLP-1, oxyntomodulin and lithium chloride in mice detected by manganese-enhanced magnetic resonance imaging (MEMRI). NeuroImage. 44 (3), pp. 1022-1031.

Preparation and characterization of medicated PAN/PVP composite fibers for better drug release profiles
Yu, D.G., Shen, X.X., Zhu, L.M., Branford-White, C.J., Bligh, S.W.A. and Yang, Y.C. 2009. Preparation and characterization of medicated PAN/PVP composite fibers for better drug release profiles. in: ICBBE 2009: 3rd international conference on bioinformatics and biomedical engineering IEEE .

Oral fast-dissolving drug delivery membranes prepared from electrospun polyvinylpyrrolidone ultrafine fibers
Yu, D.G., Shen, X.X., Branford-White, C.J., White, K.N., Zhu, L.M. and Bligh, S.W.A. 2009. Oral fast-dissolving drug delivery membranes prepared from electrospun polyvinylpyrrolidone ultrafine fibers. Nanotechnology. 20 (5), p. 055104.

Presentation of the beta-carboxamidophosphonate arrangement in substrate structures targeting HIV-1 PR
Wardle, N.J., Hudson, H.R., Matthews, R.W., Nunn, C., Vella, C. and Bligh, S.W.A. 2009. Presentation of the beta-carboxamidophosphonate arrangement in substrate structures targeting HIV-1 PR. Letters in Drug Design and Discovery. 6, pp. 139-145.

The application of magnetic resonance imaging and spectroscopy to gene therapy
So, P.W., Bhakoo, K.K., Cox, I.J., Taylor-Robinson, S.D. and Bell, J.D. 2009. The application of magnetic resonance imaging and spectroscopy to gene therapy. in: Conn, P.M. (ed.) Essential bioimaging methods Academic Press. pp. 374-398

Diagonal-SPRITE and its applications for in vivo imaging at high field
Protti, A., Herlihy, A.H., So, P.W., Tessier, J., Kalber, T. and Bell, J.D. 2009. Diagonal-SPRITE and its applications for in vivo imaging at high field. The Open Magnetic Resonance Journal. 2, pp. 1-7.

Imaging appetite regulating pathways in the central nervous system using manganese enhanced magnetic resonance imaging (MEMRI)
Parkinson, J.R.C., Chaudhri, O.B. and Bell, J.D. 2009. Imaging appetite regulating pathways in the central nervous system using manganese enhanced magnetic resonance imaging (MEMRI). Neuroendocrinology. 89 (2), pp. 121-130.

Fat distribution in men of different waist girth, fitness level and exercise habit
O'Donovan, G., Thomas, E.L., McCarthy, J., Fitzpatrick, J., Durighel, G., Mehta, S.R., Morin, S.H.X., Goldstone, A.P. and Bell, J.D. 2009. Fat distribution in men of different waist girth, fitness level and exercise habit. International Journal of Obesity. 33 (12), pp. 1356-1362.

Lifestyle-induced metabolic inflexibility and accelerated ageing syndrome: insulin resistance, friend or foe?
Nunn, A.V.W., Bell, J.D. and Guy, G.W. 2009. Lifestyle-induced metabolic inflexibility and accelerated ageing syndrome: insulin resistance, friend or foe? Nutrition & Metabolism. 6, p. 16.

Whole body magnetic resonance imaging of healthy newborn infants demonstrates increased central adiposity in Asian Indians
Modi, N., Thomas, E.L., Uthaya, S.N., Umranikar, S., Bell, J.D. and Yajnik, C. 2009. Whole body magnetic resonance imaging of healthy newborn infants demonstrates increased central adiposity in Asian Indians. Paediatric Research. 65 (5), pp. 584-587.

Folate receptor targeted bimodal liposomes for tumor magnetic resonance imaging
Kamaly, N., Kalber, T., Thanou, M., Bell, J.D. and Miller, A.D. 2009. Folate receptor targeted bimodal liposomes for tumor magnetic resonance imaging. Bioconjugate Chemistry. 20 (4), pp. 648-655.

Neonatal intrahepatocellular lipid
Thomas, E.L., Uthaya, S.N., Vasu, V., McCarthy, J., McEwan, P., Hamilton, G., Bell, J.D. and Modi, N. 2008. Neonatal intrahepatocellular lipid. Archives of Disease in Childhood. Fetal and Neonatal Edition. 93 (5), pp. F382-F383.

Cytotoxic sesquiterpenes from Ligularia platyglossa
Liu, J.Q., Zhang, M., Zhang, C.-F., Qi, H.Y., Bashall, A., Bligh, S.W.A. and Wang, Z. 2008. Cytotoxic sesquiterpenes from Ligularia platyglossa. Phytochemistry. 69 (11), pp. 2231-2236.

Characterization of fifty-one flavonoids in a Chinese herbal prescription Longdan Xiegan Decoction by high-performance liquid chromatography coupled to electrospray ionization tandem mass spectrometry and photodiode array detection
Wang, Y., Yang, L., He, Y.Q., Wang, C.-H., Welbeck, E., Bligh, S.W.A. and Wang, Z. 2008. Characterization of fifty-one flavonoids in a Chinese herbal prescription Longdan Xiegan Decoction by high-performance liquid chromatography coupled to electrospray ionization tandem mass spectrometry and photodiode array detection. Rapid Communications in Mass Spectrometry. 22 (12), pp. 1767-1778.

High performance liquid chromatography-ion trap mass spectrometric analysis for metabolites of isoline in rat urine and bile
Zhang, F., Zhong, D.F., Wang, C.-H., Bligh, S.W.A. and Wang, Z. 2008. High performance liquid chromatography-ion trap mass spectrometric analysis for metabolites of isoline in rat urine and bile. Drug Metabolism Reviews. 40, p. 216.

Quantitative analysis by HPLC-MS2 of the pyrrolizidine alkaloid adonifoline in Senecio scandens
Zhang, F., Wang, C.-H., Wang, W., Chen, L.X., Ma, H.Y., Zhang, C.-F., Zhang, M., Bligh, S.W.A. and Wang, Z. 2008. Quantitative analysis by HPLC-MS2 of the pyrrolizidine alkaloid adonifoline in Senecio scandens. Phytochemical Analysis. 19 (1), pp. 25-31.

Organophosphorus compounds: intervention in mechanisms of signal transduction relevant to proliferative, immunological and circulatory disorders
Wardle, N.J., Bligh, S.W.A. and Hudson, H.R. 2008. Organophosphorus compounds: intervention in mechanisms of signal transduction relevant to proliferative, immunological and circulatory disorders. Current Medicinal Chemistry. 15, pp. 2230-2257.

Sulfated beta-glucan derived from oat bran with potent anti-HIV activity
Wang, S.C., Bligh, S.W.A., Zhu, C.L., Shi, S.S., Wang, Z., Hu, Z.B., Crowder, J., Branford-White, C.J. and Vella, C. 2008. Sulfated beta-glucan derived from oat bran with potent anti-HIV activity. Journal of Agricultural and Food Chemistry. 56 (8), pp. 2624-2629.

Non-invasive means of measuring hepatic fat content
Mehta, S.R., Thomas, E.L., Bell, J.D., Johnston, D.G. and Taylor-Robinson, S.D. 2008. Non-invasive means of measuring hepatic fat content. World Journal of Gastroenterology. 14 (22), pp. 3476-3483.

Bimodal paramagnetic and fluorescent liposomes for cellular and tumor magnetic resonance imaging
Kamaly, N., Kalber, T., Ahmad, A., Oliver, M.H., So, P.W., Herlihy, A.H., Bell, J.D., Jorgensen, M.R. and Miller, A.D. 2008. Bimodal paramagnetic and fluorescent liposomes for cellular and tumor magnetic resonance imaging. Bioconjugate Chemistry. 19 (1), pp. 118-129.

Quantitative analysis of total retronecine esters-type pyrrolizidine alkaloids in plant by high performance liquid chromatography
Zhang, F., Wang, C.-H., Xiong, A., Wang, W., Yang, L., Branford-White, C.J., Wang, Z. and Bligh, S.W.A. 2007. Quantitative analysis of total retronecine esters-type pyrrolizidine alkaloids in plant by high performance liquid chromatography. Analytica Chimica Acta. 605 (1), pp. 94-101.

Biological fingerprinting analysis of the traditional Chinese prescription Longdan Xiegan Decoction by on/off-line comprehensive two-dimensional biochromatography
Wang, Y., Kong, L., Hu, L., Lei, X., Yang, L., Chou, G.-X., Zou, H., Wang, C.-H., Bligh, S.W.A. and Wang, Z. 2007. Biological fingerprinting analysis of the traditional Chinese prescription Longdan Xiegan Decoction by on/off-line comprehensive two-dimensional biochromatography. Journal of Chromatography B: Biomedical Sciences and Applications. 860 (2), pp. 185-194.

Pioglitazone added to conventional lipid lowering treatment in familial combined hyperlipidaemia improves parameters of metabolic control: relation to liver, muscle and regional body fat content
Thomas, E.L., Potter, E., Tosi, I., Fitzpatrick, J., Hamilton, G., Amber, V., Hughs, R., North, C., Holvoet, P., Seed, M., Betteridge, D.J., Bell, J.D. and Naoumova, R.P. 2007. Pioglitazone added to conventional lipid lowering treatment in familial combined hyperlipidaemia improves parameters of metabolic control: relation to liver, muscle and regional body fat content. Atherosclerosis. 195 (1), pp. e181-e190.

The temporal sequence of gut peptide-central nervous system interactions tracked in vivo by magnetic resonance imaging
Kuo, Y.T., Parkinson, J.R.C., Chaudhri, O.B., Herlihy, A.H., So, P.W., Dhillo, W.S., Small, C.J., Bloom, S.R. and Bell, J.D. 2007. The temporal sequence of gut peptide-central nervous system interactions tracked in vivo by magnetic resonance imaging. Journal of Neuroscience. 27 (45), pp. 12341-12348.

Structural features and anti-HIV-1 activity of novel polysaccharides from red algae Grateloupia longifolia and Grateloupia filicina
Wang, S.C., Bligh, S.W.A., Shi, S.S., Wang, Z., Hu, Z.B., Crowder, J., Branford-White, C.J. and Vella, C. 2007. Structural features and anti-HIV-1 activity of novel polysaccharides from red algae Grateloupia longifolia and Grateloupia filicina. International Journal of Biological Macromolecules. 41 (4), pp. 369-375.

Pharmacokinetic behavior of gentiopicroside from decoction of radix gentianae, gentiana macrophylla after oral administration in rats: a pharmacokinetic comaprison with gentiopicroside after oral and intravenous administration alone
Wang, C.-H., Cheng, X.M., He, Y.Q., White, K.N., Bligh, S.W.A., Branford-White, C.J. and Wang, Z. 2007. Pharmacokinetic behavior of gentiopicroside from decoction of radix gentianae, gentiana macrophylla after oral administration in rats: a pharmacokinetic comaprison with gentiopicroside after oral and intravenous administration alone. Archives of pharmacal research. 30 (9), pp. 1149-1154.

Pharmacokinetics and bioavailability of gentiopicroside from decoctions of Gentianae and Longdan Xiegan Tang after oral administration in rats: comparison with gentiopicroside alone
Wang, C.-H., Cheng, X.M., Bligh, S.W.A., White, K.N., Branford-White, C.J. and Wang, Z. 2007. Pharmacokinetics and bioavailability of gentiopicroside from decoctions of Gentianae and Longdan Xiegan Tang after oral administration in rats: comparison with gentiopicroside alone. Journal of Pharmaceutical and Biomedical Analysis. 44 (5), pp. 1113-1117.

Synthesis of a novel ‘smart’ bifunctional chelating agent 1-(2-[β,d-galactopyranosyloxy]ethyl)-7-(1-carboxy-3-[4-aminophenyl]propyl)-4,10-bis(carboxymethyl)-1,4,7,10-tetraazacyclododecane (Gal-PA-DO3A-NH2) and its Gd(III) complex
Wardle, N.J., Herlihy, A.H., So, P.W., Bell, J.D. and Bligh, S.W.A. 2007. Synthesis of a novel ‘smart’ bifunctional chelating agent 1-(2-[β,d-galactopyranosyloxy]ethyl)-7-(1-carboxy-3-[4-aminophenyl]propyl)-4,10-bis(carboxymethyl)-1,4,7,10-tetraazacyclododecane (Gal-PA-DO3A-NH2) and its Gd(III) complex. Bioorganic & medicinal chemistry. 15 (14), pp. 4714-4721.

High-performance liquid chromatography-diode array detection/electrospray ionization mass spectrometry for the simultaneous analysis of cis-, trans- and dihydro-2-glucosyloxycinnamic acid derivatives from Dendrobium medicinal plants
Yang, L., Nakamura, N., Hattori, M., Wang, Z., Bligh, S.W.A. and Xu, L. 2007. High-performance liquid chromatography-diode array detection/electrospray ionization mass spectrometry for the simultaneous analysis of cis-, trans- and dihydro-2-glucosyloxycinnamic acid derivatives from Dendrobium medicinal plants. Rapid Communications in Mass Spectrometry. 21 (12), pp. 1833-1840.

The integration of lipid-sensing and anti-inflammatory effects: how the PPARs play a role in metabolic balance
Nunn, A.V.W., Bell, J.D. and Barter, P. 2007. The integration of lipid-sensing and anti-inflammatory effects: how the PPARs play a role in metabolic balance. Nuclear Receptor. 5 (1), pp. 1-12.

You have free access to this content Creatine supplements in patients with idiopathic inflammatory myopathies who are clinically weak after conventional pharmacologic treatment: Six-month, double-blind, randomized, placebo-controlled trial
Chung, Y.L., Alexanderson, H., Pipitone, N., Morrison, C., Dastmalchi, M., Ståhl-Hallengren, C., Richards, S., Thomas, E.L., Hamilton, G., Bell, J.D., Lundberg, I.E. and Scott, D.L. 2007. You have free access to this content Creatine supplements in patients with idiopathic inflammatory myopathies who are clinically weak after conventional pharmacologic treatment: Six-month, double-blind, randomized, placebo-controlled trial. Arthritis & Rheumatism. 57 (4), pp. 694-702.

Exercise training reduces fatty acid availability and improves the insulin sensitivity of glucose metabolism
Shojaee-Moradie, F., Baynes, K.C.R., Pentecost, C., Bell, J.D., Thomas, E.L., Jackson, N.C., Stolinski, M., Whyte, M., Lovell, D., Bowes, S.B., Gibney, J., Jones, R.H. and Umpleby, A.M. 2007. Exercise training reduces fatty acid availability and improves the insulin sensitivity of glucose metabolism. Diabetologia. 50 (2), pp. 404-413.

ω-Phosphinyl-α-amino acids: synthesis, and development towards use as therapeutic agents
Wardle, N.J., Bligh, S.W.A. and Hudson, H.R. 2007. ω-Phosphinyl-α-amino acids: synthesis, and development towards use as therapeutic agents. Current Organic Chemistry. 11 (18), pp. 1635-1651.

Impact of resistant starch on body fat patterning and central appetite regulation
So, P.W., Yu, W.S., Kuo, Y.T., Wasserfall, C., Goldstone, A.P., Bell, J.D. and Frost, G.S. 2007. Impact of resistant starch on body fat patterning and central appetite regulation. PLoS ONE. 2 (12), p. e1309.

Application of magnetic resonance methods to studies of gene therapy
So, P.W., Parkes, H.G. and Bell, J.D. 2007. Application of magnetic resonance methods to studies of gene therapy. Progress in Nuclear Magnetic Resonance Spectroscopy. 51 (1), pp. 49-62.

The application of in vivo MRI and MRS in phenomic studies of murine models of disease
So, P.W. and Bell, J.D. 2007. The application of in vivo MRI and MRS in phenomic studies of murine models of disease. in: Webb, G.A. (ed.) Modern magnetic resonance The Netherlands Springer. pp. 769-786

Manganese-enhanced magnetic resonance imaging (MEMRI) without compromise of the blood–brain barrier detects hypothalamic neuronal activity in vivo
Kuo, Y.T., Herlihy, A.H., So, P.W. and Bell, J.D. 2006. Manganese-enhanced magnetic resonance imaging (MEMRI) without compromise of the blood–brain barrier detects hypothalamic neuronal activity in vivo. NMR in Biomedicine. 19 (8), pp. 1028-1034.

Differential hypothalamic neuronal activation following peripheral injection of GLP-1 and oxyntomodulin in mice detected by manganese-enhanced magnetic resonance imaging
Chaudhri, O.B., Parkinson, J.R.C., Kuo, Y.T., Druce, M.R., Herlihy, A.H., Bell, J.D., Dhillo, W.S., Stanley, S.A., Ghatei, M.A. and Bloom, S.R. 2006. Differential hypothalamic neuronal activation following peripheral injection of GLP-1 and oxyntomodulin in mice detected by manganese-enhanced magnetic resonance imaging. Biochemical and Biophysical Research Communications. 350 (2), pp. 298-306.

Determinants of adiposity during preweaning postnatal growth in appropriately grown and growth-restricted term infants
Modi, N., Thomas, E.L., Harrington, T.A.M., Uthaya, S.N., Doré, C.J. and Bell, J.D. 2006. Determinants of adiposity during preweaning postnatal growth in appropriately grown and growth-restricted term infants. Pediatric Research. 60 (3), pp. 345-348.

Critical role for peptide YY in protein-mediated satiation and body-weight regulation
Batterham, R.L., Heffron, H., Kapoor, S., Chivers, J.E., Chandarana, K., Herzog, H., le Roux, C.W., Thomas, E.L., Bell, J.D. and Withers, D.J. 2006. Critical role for peptide YY in protein-mediated satiation and body-weight regulation. Cell Metabolism. 4 (3), pp. 223-233.

Synthesis and spectral investigation of manganese(II), cadmium(II) and oxovanadium(IV) complexes with 2,6-diacetylpyridine bis(2-aminobenzoylhydrazone): crystal structure of manganese(II) and cadmium(II) complexes
Gudasi, K.B., Patil, S., Vadavi, R.S., Shenoy, R.V., Nethaji, M. and Bligh, S.W.A. 2006. Synthesis and spectral investigation of manganese(II), cadmium(II) and oxovanadium(IV) complexes with 2,6-diacetylpyridine bis(2-aminobenzoylhydrazone): crystal structure of manganese(II) and cadmium(II) complexes. Inorganica Chimica Acta. 359 (10), pp. 3229-3236.

A new phenanthrene with a spirolactone from Dendrobium chrysanthum and its anti-inflammatory activities
Yang, L., Qin, L.H., Bligh, S.W.A., Bashall, A., Zhang, C.-F., Zhang, M., Wang, Z. and Xu, L. 2006. A new phenanthrene with a spirolactone from Dendrobium chrysanthum and its anti-inflammatory activities. Bioorganic & medicinal chemistry. 14 (10), pp. 3496-3501.

Effect of nutritional counselling on hepatic, muscle and adipose tissue fat content and distribution in non-alcoholic fatty liver disease
Thomas, E.L., Brynes, A.E., Hamilton, G., Patel, N., Spong, A., Goldin, R.D., Frost, G.S., Bell, J.D. and Taylor-Robinson, S.D. 2006. Effect of nutritional counselling on hepatic, muscle and adipose tissue fat content and distribution in non-alcoholic fatty liver disease. World Journal of Gastroenterology. 12 (36), pp. 5813-5819.

Intra-cellular fat accumulation: mechanisms and implications for health
Thomas, E.L. and Bell, J.D. 2006. Intra-cellular fat accumulation: mechanisms and implications for health. International Journal of Body Composition Research. 4 (1), pp. 27-37.

Phytoestrogen levels in selected Jamaican food
Simon, G., McFarlane-Anderson, N., Fletcher, H., Golden, K., Wharfe, G., Ogegbo, O., Bligh, S.W.A. and Branford-White, C.J. 2006. Phytoestrogen levels in selected Jamaican food. West Indian Medical Journal. 55, p. 24.

MAGfect: a novel liposome formulation for MRI labelling and visualization of cells
Oliver, M.H., Ahmad, A., Kamaly, N., Perouzel, E., Caussin, A., Keller, M., Herlihy, A.H., Bell, J.D., Miller, A.D. and Jorgensen, M.R. 2006. MAGfect: a novel liposome formulation for MRI labelling and visualization of cells. Organic and Biomolecular Chemistry. 4 (18), pp. 3489-3497.

Organophosphorus chemistry: therapeutic intervention in mechanisms of viral and cellular replication
Wardle, N.J., Bligh, S.W.A. and Hudson, H.R. 2005. Organophosphorus chemistry: therapeutic intervention in mechanisms of viral and cellular replication. Current Organic Chemistry. 9 (18), pp. 1803-1828.

Multiflorane triterpene esters from the seeds of Trichosanthes kirilowii
Wu, T., Cheng, X.M., Bligh, S.W.A., Chou, G.-X., Wang, Z., Bashall, A. and Branford-White, C.J. 2005. Multiflorane triterpene esters from the seeds of Trichosanthes kirilowii. Helvetica Chimica Acta. 88 (10), pp. 2617-2623.

Muscle metabolites, detected in urine by proton spectroscopy, correlate with disease damage in juvenile idiopathic inflammatory myopathies
Chung, Y.L., Rider, L.G., Bell, J.D., Summers, R.M., Zemel, L.S., Rennebohm, R.M., Passo, M.H., Hicks, J., Miller, F.W. and Scott, D.L. 2005. Muscle metabolites, detected in urine by proton spectroscopy, correlate with disease damage in juvenile idiopathic inflammatory myopathies. Arthritis & Rheumatology. 53 (4), pp. 565-570.

Generic method for imaging transgene expression
So, P.W., Hotee, S., Herlihy, A.H. and Bell, J.D. 2005. Generic method for imaging transgene expression. Magnetic Resonance in Medicine. 54 (1), pp. 218-221.

Adiposity induced by adenovirus 5 inoculation
So, P.W., Herlihy, A.H. and Bell, J.D. 2005. Adiposity induced by adenovirus 5 inoculation. International Journal of Obesity. 29 (6), pp. 603-606.

Bi-bicyclic and bi-tricyclic compounds from Dendrobium thyrsiflorum
Zhang, G.N., Zhong, L.Y., Bligh, S.W.A., Guo, Y.L., Zhang, C.-F., Zhang, M., Wang, Z. and Xu, L. 2005. Bi-bicyclic and bi-tricyclic compounds from Dendrobium thyrsiflorum. Phytochemistry. 66 (10), pp. 1113-1120.

Excess visceral and hepatic adipose tissue in Turner syndrome determined by magnetic resonance imaging: estrogen deficiency associated with hepatic adipose content
Ostberg, J.E., Thomas, E.L., Hamilton, G., Attar, M.J.H., Bell, J.D. and Conway, G.S. 2005. Excess visceral and hepatic adipose tissue in Turner syndrome determined by magnetic resonance imaging: estrogen deficiency associated with hepatic adipose content. Journal of Clinical Endocrinology and Metabolism. 90 (5), pp. 2631-2635.

In vivo measurements of T1 relaxation times in mouse brain associated with different modes of systemic administration of manganese chloride
Kuo, Y.T., Herlihy, A.H., So, P.W., Bhakoo, K.K. and Bell, J.D. 2005. In vivo measurements of T1 relaxation times in mouse brain associated with different modes of systemic administration of manganese chloride. Journal of Magnetic Resonance Imaging. 21 (4), pp. 334-339.

The role of insulin receptor substrate 2 in hypothalamic and β cell function
Choudhury, A.I., Heffron, H., Smith, M.A., Al-Qassab, H., Xu, A.W., Selman, C., Simmgen, M., Clements, M., Claret, M., MacColl, G., Bedford, D.C., Hisadome, K., Diakonov, I., Moosajee, V., Bell, J.D., Speakman, J.R., Batterham, R.L., Barsh, G.S., Ashford, M.L.J. and Withers, D.J. 2005. The role of insulin receptor substrate 2 in hypothalamic and β cell function. Journal of Clinical Investigation. 115 (4), pp. 940-950.

Simultaneous determination of six isoflavonoids in commercial Radix Astragali by HPLC-UV
Wu, T., Bligh, S.W.A., Gu, L.-H., Wang, Z., Liu, H.P., Cheng, X.M., Branford-White, C.J. and Hu, Z.B. 2005. Simultaneous determination of six isoflavonoids in commercial Radix Astragali by HPLC-UV. Fitoterapia. 76 (2), pp. 157-165.

Altered adiposity after extremely preterm birth
Uthaya, S.N., Thomas, E.L., Hamilton, G., Doré, C.J., Bell, J.D. and Modi, N. 2005. Altered adiposity after extremely preterm birth. Pediatric Research. 57 (2), pp. 211-215.

Phosphorus-31 brain MR spectroscopy in women during and after pregnancy compared with nonpregnant control subjects
Holdcroft, A., Hall, L., Hamilton, G., Counsell, S.J., Bydder, G.M. and Bell, J.D. 2005. Phosphorus-31 brain MR spectroscopy in women during and after pregnancy compared with nonpregnant control subjects. American Journal of Neuroradiology. 26 (2), pp. 352-356.

Veganism and its relationship with insulin resistance and intramyocellular lipid
Goff, L.M., Bell, J.D., So, P.W., Dornhorst, A. and Frost, G.S. 2005. Veganism and its relationship with insulin resistance and intramyocellular lipid. European Journal of Clinical Nutrition. 59 (2), pp. 291-298.

Hepatic triglyceride content and its relation to body adiposity: a magnetic resonance imaging and proton magnetic resonance spectroscopy study
Thomas, E.L., Hamilton, G., Patel, N., O'Dwyer, R., Doré, C.J., Goldin, R.D., Bell, J.D. and Taylor-Robinson, S.D. 2005. Hepatic triglyceride content and its relation to body adiposity: a magnetic resonance imaging and proton magnetic resonance spectroscopy study. Gut. 54 (1), pp. 122-127.

Pharmacokinetics and tissue distribution of gentiopicroside following oral and intravenous administration in mice
Wang, C.-H., Wang, Z., Bligh, S.W.A., White, K.N. and Branford-White, C.J. 2004. Pharmacokinetics and tissue distribution of gentiopicroside following oral and intravenous administration in mice. European Journal of Drug Metabolism and Pharmacokinetics. 29 (3), pp. 199-203.

Contrast enhancement of short T2 tissues using ultrashort TE (UTE) pulse sequences
Robson, M.D., Gatehouse, P.D., So, P.W., Bell, J.D. and Bydder, G.M. 2004. Contrast enhancement of short T2 tissues using ultrashort TE (UTE) pulse sequences. Clinical Radiology. 59 (8), pp. 720-726.

Links Familial partial lipodystrophy associated with compound heterozygosity for novel mutations in the LMNA gene
Savage, D.B., McFarlane, I.A., Barroso, I., Soos, M.A., Powlson, A., Thomas, E.L., Bell, J.D., Scobie, I., Belchetz, P.E., Kelly, W.F., Halsall, D.J., Schafer, A.J. and O’Rahilly, S. 2004. Links Familial partial lipodystrophy associated with compound heterozygosity for novel mutations in the LMNA gene. Diabetologia. 47 (4), pp. 753-756.

Elevated fasting plasma ghrelin in Prader-Willi Syndrome adults is not solely explained by their reduced visceral adiposity and insulin resistance
Goldstone, A.P., Thomas, E.L., Brynes, A.E., Castroman, G., Edwards, R., Ghatei, M.A., Frost, G.S., Holland, A., Grossman, A.B., Korbonits, M., Bloom, S.R. and Bell, J.D. 2004. Elevated fasting plasma ghrelin in Prader-Willi Syndrome adults is not solely explained by their reduced visceral adiposity and insulin resistance. Journal of Clinical Endocrinology and Metabolism. 89 (4), pp. 1718-1726.

Distribution of adipose tissue in the newborn
Harrington, T.A.M., Thomas, E.L., Modi, N., Frost, G.S. and Bell, J.D. 2004. Distribution of adipose tissue in the newborn. Pediatric Research. 55 (3), pp. 437-441.

Adipose tissue magnetic resonance imaging in the newborn
Uthaya, S.N., Bell, J.D. and Modi, N. 2004. Adipose tissue magnetic resonance imaging in the newborn. Hormone Research. 62 (sup.3), pp. 143-148.

Taraxer-14-en-3β-ol, an anti-inflammatory compound from Sterculia foetida L.
Naik, D.G., Mujumdar, A.M., Waghole, R.J., Misar, A.V., Bligh, S.W.A., Bashall, A. and Crowder, J. 2004. Taraxer-14-en-3β-ol, an anti-inflammatory compound from Sterculia foetida L. Planta Medica. 70 (1), pp. 68-69.

Nuclear receptor corepressor RIP140 regulates fat accumulation
Leonardsson, G., Steel, J.H., Christian, M., Pocock, V., Milligan, S., Bell, J.D., So, P.W., Medina-Gomez, G., Vidal-Puig, A., White, R. and Parker, M.G. 2004. Nuclear receptor corepressor RIP140 regulates fat accumulation. Proceedings of the National Academy of Sciences. 101 (22), pp. 8437-8442.

cis-Eudesmane Sesquiterpene Glycosides from Liriope muscari and Ophiopogon japonicus
Cheng, Z.H., Wu, T., Bligh, S.W.A., Bashall, A. and Yu, B.Y. 2004. cis-Eudesmane Sesquiterpene Glycosides from Liriope muscari and Ophiopogon japonicus. Journal of Natural Products. 67 (10), pp. 1761-1763.

The application of magnetic resonance imaging and spectroscopy to gene therapy
Bhakoo, K.K., Bell, J.D., Cox, I.J. and Taylor-Robinson, S.D. 2004. The application of magnetic resonance imaging and spectroscopy to gene therapy. in: Ashkenazi, A., Wells, J.A. and Yuan, J. (ed.) Methods in enzymology Elsevier.

Fluorescence properties of green fluorescent protein FRET pairs concatenated with the small G protein, Rac, and its interacting domain of the kinase, p21-activated kinase
Collinson, A.D., Bligh, S.W.A., Graham, D.L., Mott, H.R., Chalk, P.A., Korniotis, N. and Lowe, P.N. 2004. Fluorescence properties of green fluorescent protein FRET pairs concatenated with the small G protein, Rac, and its interacting domain of the kinase, p21-activated kinase. Assay and Drug Development Technologies. 2 (6), pp. 659-673.

N-acetyl aspartate estimation: a potential method for determining neuronal loss in the transmissible spongiform encephalopathies
Chung, Y.L., Barr, J., Bhakoo, K.K., Williams, S.C.R., Bell, J.D. and Fraser, J.R. 2003. N-acetyl aspartate estimation: a potential method for determining neuronal loss in the transmissible spongiform encephalopathies. Neuropathology and Applied Neurobiology. 29 (5), pp. 445-450.

Human metabolic syndrome resulting from dominant-negative mutations in the nuclear receptor peroxisome proliferator-activated receptor-γ
Savage, D.B., Tan, G.D., Acerini, C.L., Jebb, S.A., Agostini, M., Gurnell, M., Williams, R.L., Umpleby, A.M., Thomas, E.L., Bell, J.D., Dixon, A.K., Dunne, F., Boiani, R., Cinti, S., Vidal-Puig, A., Karpe, F., Chatterjee, V.K.K. and O'Rahilly, S. 2003. Human metabolic syndrome resulting from dominant-negative mutations in the nuclear receptor peroxisome proliferator-activated receptor-γ. Diabetes. 52 (4), p. 910.

Carbohydrate-induced manipulation of insulin sensitivity independently of intramyocellular lipids
Goff, L.M., Frost, G.S., Hamilton, G., Thomas, E.L., Dhillo, W.S., Dornhorst, A. and Bell, J.D. 2003. Carbohydrate-induced manipulation of insulin sensitivity independently of intramyocellular lipids. British Journal of Nutrition. 89 (3), pp. 365-375.

Influence of undersampling on magnetic resonance imaging measurements of intra-abdominal adipose tissue
Thomas, E.L. and Bell, J.D. 2003. Influence of undersampling on magnetic resonance imaging measurements of intra-abdominal adipose tissue. International Journal of Obesity. 27 (2), pp. 211-218.

Urinary levels of creatine and other metabolites in the assessment of polymyositis and dermatomyositis
Chung, Y.L., Wassif, W.S., Bell, J.D., Hurley, M. and Scott, D.L. 2003. Urinary levels of creatine and other metabolites in the assessment of polymyositis and dermatomyositis. Rheumatology. 42 (2), pp. 298-303.

Hypothalamic neuropeptides and regulation of fat mass in Prader-Willi syndrome
Goldstone, A.P., Unmehopa, U.A., Thomas, E.L., Brynes, A.E., Bell, J.D., Frost, G.S., Ghatei, M.A., Holland, A., Bloom, S.R. and Swaab, D.F. 2003. Hypothalamic neuropeptides and regulation of fat mass in Prader-Willi syndrome. in: Eiholzer, U., l’Allemand, D. and Zipf, W.B. (ed.) Prader-Willi syndrome as a model for obesity: international symposium, Zurich, October 18-19, 2002 Karger Medical and Scientific Publishers. pp. 31-43

Measurement of dissociation constants of inhibitors binding to Src SH2 domain protein by non-covalent electrospray ionization mass spectrometry
Bligh, S.W.A., Haley, T. and Lowe, P.N. 2003. Measurement of dissociation constants of inhibitors binding to Src SH2 domain protein by non-covalent electrospray ionization mass spectrometry. Journal of Molecular Recognition. 16 (3), pp. 139-148.

Reaction of (C-(6-aminomethyl-pyridin-2-yl)methylamine)chloroplatinum(II) with nucleosides and its biological activity
Bligh, S.W.A., Bashall, A., Garrud, C., McPartlin, M., Wardle, N.J., White, K.N., Padhye, S., Barve, V. and Kundu, G. 2003. Reaction of (C-(6-aminomethyl-pyridin-2-yl)methylamine)chloroplatinum(II) with nucleosides and its biological activity. Dalton Transactions. 2003 (2), pp. 184-188.

How chemistry brought me to the life-sciences interface
Bligh, S.W.A. 2003. How chemistry brought me to the life-sciences interface. Science.

Letter: Digenic inheritance of severe insulin resistance in a human pedigree
Savage, D.B., Agostini, M., Barroso, I., Gurnell, M., Luan, J.A., Meirhaeghe, A., Harding, A.H., Ihrke, G., Rajanayagam, O., Soos, M.A., George, S., Birger, D., Thomas, E.L., Bell, J.D., Meera, K., Ross, R.J., Vidal-Puig, A., Wareham, N.J., O'Rahilly, S., Chatterjee, V.K.K. and Schafer, A.J. 2002. Letter: Digenic inheritance of severe insulin resistance in a human pedigree. Nature Genetics. 31 (4), pp. 379-384.

Resting metabolic rate, plasma leptin concentrations, leptin receptor expression, and adipose tissue measured by whole-body magnetic resonance imaging in women with Prader-Willi syndrome
Goldstone, A.P., Brynes, A.E., Thomas, E.L., Bell, J.D., Frost, G.S., Holland, A., Ghatei, M.A. and Bloom, S.R. 2002. Resting metabolic rate, plasma leptin concentrations, leptin receptor expression, and adipose tissue measured by whole-body magnetic resonance imaging in women with Prader-Willi syndrome. American Journal of Clinical Nutition. 75 (3), pp. 468-475.

Fast and reproducible method for the direct quantitation of adipose tissue in newborn infants
Harrington, T.A.M., Thomas, E.L., Modi, N., Frost, G.S., Coutts, G.A. and Bell, J.D. 2002. Fast and reproducible method for the direct quantitation of adipose tissue in newborn infants. Lipids. 37 (1), pp. 95-100.

IUPAC-NIST solubility data series. 76. Solubility of ethyne in liquids
Fogg, P.G.T., Bligh, S.W.A., Derrick, M.E., Yampol’skii, Y.P., Clever, H.L., Skrzecz, A. and Young, C.L. 2001. IUPAC-NIST solubility data series. 76. Solubility of ethyne in liquids. Journal of Physical and Chemical Reference Data. 30 (6), pp. 1693-1875.

Evidence for altered hepatic gluconeogenesis in patients with cirrhosis using in vivo 31-phosphorus magnetic resonance spectroscopy
Changani, K.K., Jalan, R., Cox, I.J., Ala-Korpela, M., Bhakoo, K.K., Taylor-Robinson, S.D. and Bell, J.D. 2001. Evidence for altered hepatic gluconeogenesis in patients with cirrhosis using in vivo 31-phosphorus magnetic resonance spectroscopy. Gut. 49 (4), pp. 557-564.

Visceral adipose tissue and metabolic complications of obesity are reduced in Prader-Willi syndrome female adults: evidence for novel influences on body fat distribution
Goldstone, A.P., Thomas, E.L., Brynes, A.E., Bell, J.D., Frost, G.S., Saeed, N., Hajnal, J.V., Howard, J.K., Holland, A. and Bloom, S.R. 2001. Visceral adipose tissue and metabolic complications of obesity are reduced in Prader-Willi syndrome female adults: evidence for novel influences on body fat distribution. Journal of Clinical Endocrinology and Metabolism. 86 (9), pp. 4330-4338.

Dimeric yttrium(III) and neodymium(III) macrocyclic complexes: potential catalysts for hydrolysis of double-stranded DNA
Bligh, S.W.A., Choi, N., Evagorou, E.G., McPartlin, M. and White, K.N. 2001. Dimeric yttrium(III) and neodymium(III) macrocyclic complexes: potential catalysts for hydrolysis of double-stranded DNA. Journal of the Chemical Society, Dalton Transactions. 2001 (21), pp. 3169-3172.

In vivo evaluation of the effects of continuous exercise on skeletal muscle triglycerides in trained humans
Rico-Sanz, J., Moosavi, M., Thomas, E.L., McCarthy, J., Coutts, G.A., Saeed, N. and Bell, J.D. 2000. In vivo evaluation of the effects of continuous exercise on skeletal muscle triglycerides in trained humans. Lipids. 35 (12), pp. 1313-1315.

Investigation of human low-density lipoprotein by 1H nuclear magnetic resonance spectroscopy:  mobility of phosphatidylcholine and sphingomyelin headgroups characterizes the surface layer
Murphy, H.C., Burns, S.P., White, J.J., Bell, J.D. and Iles, R.A. 2000. Investigation of human low-density lipoprotein by 1H nuclear magnetic resonance spectroscopy:  mobility of phosphatidylcholine and sphingomyelin headgroups characterizes the surface layer. Biochemistry. 39 (32), pp. 9763-9770.

Bioenergetic targeting during organ preservation: 31P magnetic resonance spectroscopy investigations into the use of fructose to sustain hepatic ATP turnover during cold hypoxia in porcine livers
Changani, K.K., Fuller, B.J., Bell, J.D., Taylor-Robinson, S.D. and Davidson, B.R. 2000. Bioenergetic targeting during organ preservation: 31P magnetic resonance spectroscopy investigations into the use of fructose to sustain hepatic ATP turnover during cold hypoxia in porcine livers. Cryobiology. 41 (1), pp. 72-87.

Assessing gene expression in vivo: magnetic resonance imaging and spectroscopy
Bell, J.D. and Taylor-Robinson, S.D. 2000. Assessing gene expression in vivo: magnetic resonance imaging and spectroscopy. Gene Therapy. 7 (15), pp. 1259-1264.

Preferential loss of visceral fat following aerobic exercise, measured by magnetic resonance imaging
Thomas, E.L., Brynes, A.E., McCarthy, J., Goldstone, A.P., Hajnal, J.V., Saeed, N., Frost, G.S. and Bell, J.D. 2000. Preferential loss of visceral fat following aerobic exercise, measured by magnetic resonance imaging. Lipids. 35 (7), pp. 769-776.

Characterization of 111In3+ complexes of DTPA amide derivatives: biodistribution and clearance studied by gamma imaging
Prata, M.I.M., Santos, A.C., Bligh, S.W.A., Chowdhury, A.H.M.S., Geraldes, C.F.G.C. and de Lima, J.J.P. 2000. Characterization of 111In3+ complexes of DTPA amide derivatives: biodistribution and clearance studied by gamma imaging. Nuclear Medicine and Biology. 27 (6), pp. 605-610.

Increased availability of central benzodiazepine receptors in patients with chronic hepatic encephalopathy and alcohol related cirrhosis
Jalan, R., Turjanski, N., Taylor-Robinson, S.D., Koepp, M.J., Richardson, M.P., Wilson, J.A., Bell, J.D. and Brooks, D.J. 2000. Increased availability of central benzodiazepine receptors in patients with chronic hepatic encephalopathy and alcohol related cirrhosis. Gut. 46 (4), pp. 546-552.

Cortical dysfunction in non-demented Parkinson's disease patients: A combined 31P-MRS and 18FDG-PET study
Hu, M.T.M., Taylor-Robinson, S.D., Chaudhuri, K.R., Bell, J.D., Labbé, C., Cunningham, V.J., Koepp, M.J., Hammers, A., Morris, R.G., Turjanski, N. and Brooks, D.J. 2000. Cortical dysfunction in non-demented Parkinson's disease patients: A combined 31P-MRS and 18FDG-PET study. Brain. 123 (2), pp. 340-352.

Synthesis and structural properties of metal complexes of dialkyl α-hydroxyiminophosphonates
Bligh, S.W.A., Choi, N., McGrath, C.M., McPartlin, M. and Woodroffe, T.M. 2000. Synthesis and structural properties of metal complexes of dialkyl α-hydroxyiminophosphonates. Journal of the Chemical Society, Dalton Transactions. 2000 (15), pp. 2587-2594.

Conflicting MRI signals from gliosis and neuronal vacuolation in prion diseases
Chung, Y.L., Williams, A., Ritchie, D., Williams, S.C.R., Changani, K.K., Hope, J. and Bell, J.D. 1999. Conflicting MRI signals from gliosis and neuronal vacuolation in prion diseases. NeuroReport. 10 (17), pp. 3471-3477.

Cerebral proton and phosphorus-31 magnetic resonance spectroscopy in patients with subclinical hepatic encephalopathy
Taylor-Robinson, S.D., Buckley, C., Changani, K.K., Hodgson, H.J.F. and Bell, J.D. 1999. Cerebral proton and phosphorus-31 magnetic resonance spectroscopy in patients with subclinical hepatic encephalopathy. Liver. 19 (5), pp. 389-398.

Improved preservation solutions for organ storage: a dynamic study of hepatic metabolism
Changani, K.K., Fuller, B.J., Bell, J.D., Taylor-Robinson, S.D., Moore, D.P. and Davidson, B.R. 1999. Improved preservation solutions for organ storage: a dynamic study of hepatic metabolism. Transplantation. 68 (3), pp. 345-355.

Evidence for cortical dysfunction in clinically non-demented patients with Parkinson’s disease: a proton MR spectroscopy study
Hu, M.T.M., Taylor-Robinson, S.D., Chaudhuri, K.R., Bell, J.D., Morris, R.G., Clough, C., Brooks, D.J. and Turjanski, N. 1999. Evidence for cortical dysfunction in clinically non-demented patients with Parkinson’s disease: a proton MR spectroscopy study. Journal of Neurology, Neurosurgery, and Psychiatry. 67 (1), pp. 20-26.

Relation of triglyceride stores in skeletal muscle cells to central obesity and insulin sensitivity in European and South Asian men
Forouhi, N.G., Jenkinson, G., Thomas, E.L., Mullick, S., Mierisová, Ŝ., Bhonsle, U., McKeigue, P.M. and Bell, J.D. 1999. Relation of triglyceride stores in skeletal muscle cells to central obesity and insulin sensitivity in European and South Asian men. Diabetologia. 42 (8), pp. 932-935.

Brain bioenergetics in murine models of scrapie using in vivo 31P magnetic resonance spectroscopy
Chung, Y.L., Williams, S.C.R., Hope, J. and Bell, J.D. 1999. Brain bioenergetics in murine models of scrapie using in vivo 31P magnetic resonance spectroscopy. NeuroReport. 10 (9), pp. 1899-1901.

Incorporation of metabolite prior knowledge for data analysis: biochemical implications of dynamic 31P NMR ex vivo pig liver studies
Changani, K.K., Ala-Korpela, M., Fuller, B.J., Mierisová, Ŝ., Bryant, D.J., Taylor-Robinson, S.D., Davidson, B.R. and Bell, J.D. 1999. Incorporation of metabolite prior knowledge for data analysis: biochemical implications of dynamic 31P NMR ex vivo pig liver studies. NMR in Biomedicine. 12 (4), pp. 197-204.

Non-ionic bulky Gd(III) DTPA-bisamide complexes as potential contrast agents for magnetic resonance imaging
Bligh, S.W.A., Chowdhury, A.H.M.S., Kennedy, D., Luchinat, C. and Parigi, G. 1999. Non-ionic bulky Gd(III) DTPA-bisamide complexes as potential contrast agents for magnetic resonance imaging. Magnetic Resonance in Medicine. 41 (4), pp. 767-773.

Angiotensin-converting-enzyme gene insertion/deletion polymorphism and response to physical training
Montgomery, H., Clarkson, P., Barnard, M.L., Bell, J.D., Brynes, A.E., Hajnal, J.V., Hemingway, H., Mercer, D., Jarman, P., Marshall, R., Prasad, K., Rayson, M., Saeed, N., Thomas, E.L., Jubb, M., World, M., Dollery, C., Talmud, P. and Humphries, S.E. 1999. Angiotensin-converting-enzyme gene insertion/deletion polymorphism and response to physical training. The Lancet. 353 (9152), pp. 541-545.

Relation between proton magnetic resonance spectroscopy within 18 hours of birth asphyxia and neurodevelopment at 1 year of age
Hanrahan, J.D., Cox, I.J., Azzopardi, D., Cowan, F.M., Sargentoni, J., Bell, J.D., Bryant, D.J. and Edwards, A.D. 1999. Relation between proton magnetic resonance spectroscopy within 18 hours of birth asphyxia and neurodevelopment at 1 year of age. Developmental Medicine & Child Neurology. 41 (2), pp. 76-82.

Body fat metabolism: observation by MR imaging and spectroscopy
Thomas, E.L. and Bell, J.D. 1999. Body fat metabolism: observation by MR imaging and spectroscopy. in: Young, I.R. (ed.) Magnetic resonance imaging and spectroscopy in medicine and biology Wiley.

Diversity in levels of intracellular total creatine and triglycerides in human skeletal muscles observed by 1H-MRS
Rico-Sanz, J., Thomas, E.L., Jenkinson, G., Mierisová, Ŝ., Iles, R.A. and Bell, J.D. 1999. Diversity in levels of intracellular total creatine and triglycerides in human skeletal muscles observed by 1H-MRS. Journal of Applied Physiology. 87 (6), pp. 2068-2072.

Magnetic resonance: in-vivo NMR, applications – other nuclei
Bell, J.D., Thomas, E.L. and Changani, K.K. 1999. Magnetic resonance: in-vivo NMR, applications – other nuclei. in: Lindon, J. (ed.) Encyclopedia of spectroscopy and spectrometry London Academic Press.

Metabolic changes underlying 31P MR spectral alterations in human hepatic tumours
Bell, J.D. and Bhakoo, K.K. 1998. Metabolic changes underlying 31P MR spectral alterations in human hepatic tumours. NMR in Biomedicine. 11 (7), pp. 354-359.

Critical assessment of in vivo13C NMR spectroscopy and gas–liquid chromatography in the study of adipose tissue composition
Thomas, E.L., Cunnane, S.C. and Bell, J.D. 1998. Critical assessment of in vivo13C NMR spectroscopy and gas–liquid chromatography in the study of adipose tissue composition. NMR in Biomedicine. 11 (6), pp. 290-296.

Evaluation of the stability of the proton chemical shifts of some metabolites other than water during thermal cycling of normal human muscle tissue
Young, I.R., Bell, J.D., Hajnal, J.V., Jenkinson, G. and Ling, J. 1998. Evaluation of the stability of the proton chemical shifts of some metabolites other than water during thermal cycling of normal human muscle tissue. Journal of Magnetic Resonance Imaging. 8 (5), pp. 1114-1118.

Persistent increase in cerebral lactate concentration after birth asphyxia
Hanrahan, J.D., Cox, I.J., Edwards, A.D., Cowan, F.M., Sargentoni, J., Bell, J.D., Bryant, D.J., Rutherford, M.A. and Azzopardi, D. 1998. Persistent increase in cerebral lactate concentration after birth asphyxia. Pediatric Research. 44 (3), pp. 304-311.

Intracellular and extracellular skeletal muscle triglyceride metabolism during alternating intensity exercise in humans
Rico-Sanz, J., Hajnal, J.V., Thomas, E.L., Mierisová, Ŝ., Ala-Korpela, M. and Bell, J.D. 1998. Intracellular and extracellular skeletal muscle triglyceride metabolism during alternating intensity exercise in humans. Journal of Physiology. 510 (2), pp. 615-622.

Non-invasive metabolic assessment of human donor livers: metabolite assignment in 31P magnetic resonance spectroscopy
Changani, K.K., Taylor-Robinson, S.D., Bell, J.D., Fuller, B.J. and Davidson, B.R. 1998. Non-invasive metabolic assessment of human donor livers: metabolite assignment in 31P magnetic resonance spectroscopy. Transplantation. 65 (11), pp. 1526-1527.

Human gene for physical performance
Montgomery, H., Marshall, R., Hemingway, H., Myerson, S., Clarkson, P., Dollery, C., Hayward, M., Holliman, D.E., Jubb, M., World, M., Thomas, E.L., Brynes, A.E., Saeed, N., Barnard, M.L., Bell, J.D., Prasad, K., Rayson, M., Talmud, P. and Humphries, S.E. 1998. Human gene for physical performance. Nature. 393 (6682), pp. 221-222.

13C-Glycogen deposition during pregnancy in the rat following routine meal feeding
Changani, K.K., Bell, J.D. and Iles, R.A. 1998. 13C-Glycogen deposition during pregnancy in the rat following routine meal feeding. Biochimica et Biophysica Acta: general subjects. 1380 (2), pp. 198-208.

Magnetic resonance imaging of total body fat
Thomas, E.L., Saeed, N., Hajnal, J.V., Brynes, A.E., Goldstone, A.P., Frost, G.S. and Bell, J.D. 1998. Magnetic resonance imaging of total body fat. Journal of Applied Physiology. 85 (5), pp. 1778-1785.

A comparison of ATP recovery or phosphomonoester/inorganic phosphate ratio to assess metabolic activity in liver at hypothermia: a 31P NMR study
Changani, K.K., Davidson, B.R., Bell, J.D., Taylor-Robinson, S.D. and Fuller, B.J. 1998. A comparison of ATP recovery or phosphomonoester/inorganic phosphate ratio to assess metabolic activity in liver at hypothermia: a 31P NMR study. CryoLetters. 19, pp. 183-188.

Enhanced energy metabolism at hypothermia following addition of a prostacyclin derivative in porcine liver
Changani, K.K., Davidson, B.R., Bell, J.D., Taylor-Robinson, S.D. and Fuller, B.J. 1998. Enhanced energy metabolism at hypothermia following addition of a prostacyclin derivative in porcine liver. CryoLetters. 19, pp. 131-140.

Depression of liver mitochondrial complex II-linked respiration following cooling: beneficial effects of using a prostacyclin analogue during hypothermia
Changani, K.K., Bell, J.D., Brooks, K.J., Fuller, B.J., Taylor-Robinson, S.D., Davidson, B.R., Brookes, P.S. and Bates, T.E. 1998. Depression of liver mitochondrial complex II-linked respiration following cooling: beneficial effects of using a prostacyclin analogue during hypothermia. CryoLetters. 19, pp. 71-78.

Synthesis of novel α-functionalized phosphinic acid derivatives of thiophene and the first crystal structure of an α-hydroxyalkylphosphinate
Bligh, S.W.A., McPartlin, M., Sanganee, M.J., Woodroffe, T.M. and Geraldes, C.F.G.C. 1998. Synthesis of novel α-functionalized phosphinic acid derivatives of thiophene and the first crystal structure of an α-hydroxyalkylphosphinate. Chemical Communications. 1998 (19), pp. 2073-2074.

A gadolinium cryptate with two coordinated water molecules
Bligh, S.W.A., Drew, M.G.B., Martin, N., Maubert, B. and Nelson, J. 1998. A gadolinium cryptate with two coordinated water molecules. Journal of the Chemical Society, Dalton Transactions. 1998 (22), pp. 3711-3714.

Assessment of quantitative artificial neural network analysis in a metabolically dynamic ex vivo31p NMR pig liver study
Ala-Korpela, M., Changani, K.K., Hiltunen, Y., Bell, J.D., Fuller, B.J., Bryant, D.J., Taylor-Robinson, S.D. and Davidson, B.R. 1997. Assessment of quantitative artificial neural network analysis in a metabolically dynamic ex vivo31p NMR pig liver study. Magnetic Resonance in Medicine. 38 (5), pp. 840-844.

In vivo and in vitro hepatic 31P magnetic resonance spectroscopy and electron microscopy of the cirrhotic liver
Taylor-Robinson, S.D., Sargentoni, J., Bell, J.D., Saeed, N., Changani, K.K., Davidson, B.R., Rolles, K., Burroughs, A.K., Hodgson, H.J.F., Foster, C.S. and Cox, I.J. 1997. In vivo and in vitro hepatic 31P magnetic resonance spectroscopy and electron microscopy of the cirrhotic liver. Liver. 17 (4), pp. 198-209.

In vivo assessment of metabolic perturbations following alanine and glucagon administration using 31P-MRS in the rat
Changani, K.K., Barnard, M.L., Bell, J.D., Thomas, E.L., Williams, S.C.R., Bloom, S.R. and Iles, R.A. 1997. In vivo assessment of metabolic perturbations following alanine and glucagon administration using 31P-MRS in the rat. Biochimica et Biophysica Acta: general subjects. 1335 (3), pp. 290-304.

Noninvasive characterization of neonatal adipose tissue by 13C magnetic resonance spectroscopy
Thomas, E.L., Hanrahan, J.D., Ala-Korpela, M., Jenkinson, G., Azzopardi, D., Iles, R.A. and Bell, J.D. 1997. Noninvasive characterization of neonatal adipose tissue by 13C magnetic resonance spectroscopy. Lipids. 32 (6), pp. 645-651.

Evidence for distinct behaviour of phosphatidylcholine and sphingomyelin at the low density lipoprotein surface
Murphy, H.C., Ala-Korpela, M., White, J.J., Raoof, A., Bell, J.D., Barnard, M.L., Burns, S.P. and Iles, R.A. 1997. Evidence for distinct behaviour of phosphatidylcholine and sphingomyelin at the low density lipoprotein surface. Biochemical and Biophysical Research Communications. 234 (3), pp. 733-737.

Non-invasive assessment of ATP regeneration potential of the preserved donor liver
Changani, K.K., Fuller, B.J., Bryant, D.J., Bell, J.D., Ala-Korpela, M., Taylor-Robinson, S.D., Moore, D.P. and Davidson, B.R. 1997. Non-invasive assessment of ATP regeneration potential of the preserved donor liver. Journal of Hepatology. 26 (2), pp. 336-342.

A novel hexaaza macrocycle with methylenephosphonate pendant arms: a potential useful chelate for biomedical applications
Bligh, S.W.A., Choi, N., Geraldes, C.F.G.C., Knoke, S., McPartlin, M., Sanganee, M.J. and Woodroffe, T.M. 1997. A novel hexaaza macrocycle with methylenephosphonate pendant arms: a potential useful chelate for biomedical applications. Journal of the Chemical Society, Dalton Transactions. 1997 (21), pp. 4119-4126.

Hexaaza and octaaza macrocycles with 2-hydroxy 3,5-dimethylbenzyl pendant arms
Bligh, S.W.A., Choi, N., Evagorou, E.G. and McPartlin, M. 1997. Hexaaza and octaaza macrocycles with 2-hydroxy 3,5-dimethylbenzyl pendant arms. Journal of the Chemical Society, Perkin Transactions. 1997 (21), pp. 3151-3156.

The application of NMR spectroscopy to the study of apoptosis
Bhakoo, K.K. and Bell, J.D. 1997. The application of NMR spectroscopy to the study of apoptosis. Cellular and Molecular Biology. 43 (5), pp. 621-629.

Changes in adipose tissue composition in malnourished patients before and after liver transplantation: A carbon-13 magnetic resonance spectroscopy and gas-liquid chromatography study
Thomas, E.L., Taylor-Robinson, S.D., Barnard, M.L., Frost, G.S., Sargentoni, J., Davidson, B.R., Cunnane, S.C. and Bell, J.D. 1997. Changes in adipose tissue composition in malnourished patients before and after liver transplantation: A carbon-13 magnetic resonance spectroscopy and gas-liquid chromatography study. Hepatology. 25 (1), pp. 178-183.

Metabolic changes associated with vacuolation in murine models of scrapie using in vitro 1H-NMR spectroscopy
Chung, Y.L., Williams, A., Chong, A., Hope, J., Williams, S.C.R. and Bell, J.D. 1996. Metabolic changes associated with vacuolation in murine models of scrapie using in vitro 1H-NMR spectroscopy. NMR in Biomedicine. 9 (8), pp. 359-363.

Hepatic nucleotide triphosphate regeneration following a period of brief hypothermic reperfusion in the pig model: an in vitro 31P-NMR study
Changani, K.K., Fuller, B.J., Bell, J.D., Bryant, D.J., Moore, D.P., Taylor-Robinson, S.D. and Davidson, B.R. 1996. Hepatic nucleotide triphosphate regeneration following a period of brief hypothermic reperfusion in the pig model: an in vitro 31P-NMR study. Transplantation. 62 (6), pp. 787-793.

Characterisation of secondary metabolites associated with neutrophil apoptosis
Nunn, A.V.W., Barnard, M.L., Bhakoo, K.K., Murray, J., Chilvers, E.J. and Bell, J.D. 1996. Characterisation of secondary metabolites associated with neutrophil apoptosis. FEBS Letters. 392 (3), pp. 295-298.

Effects of n-3 fatty acids on the NMR profile of plasma lipoproteins
Bell, J.D., Barnard, M.L., Parkes, H.G., Thomas, E.L., Brennan, C.H., Cunnane, S.C. and Dagnelie, P.C. 1996. Effects of n-3 fatty acids on the NMR profile of plasma lipoproteins. The Journal of Lipid Research. 37 (8), pp. 1664-1674.

Automated feature extraction for the classification of human in vivo13C NMR spectra using statistical pattern recognition and wavelets
Tate, A.R., Watson, D., Eglen, S., Arvanitis, T.N., Thomas, E.L. and Bell, J.D. 1996. Automated feature extraction for the classification of human in vivo13C NMR spectra using statistical pattern recognition and wavelets. Magnetic Resonance in Medicine. 35 (6), pp. 834-840.

Development of a rapid and efficient magnetic resonance imaging technique for analysis of body fat distribution
Barnard, M.L., Schwieso, J.E., Thomas, E.L., Bell, J.D., Saeed, N., Frost, G.S., Bloom, S.R. and Hajnal, J.V. 1996. Development of a rapid and efficient magnetic resonance imaging technique for analysis of body fat distribution. NMR in Biomedicine. 9 (4), pp. 156-164.

Cerebral metabolism within 18 hours of birth asphyxia: a proton magnetic resonance spectroscopy study
Hanrahan, J.D., Sargentoni, J., Azzopardi, D., Manji, K., Cowan, F.M., Rutherford, M.A., Cox, I.J., Bell, J.D., Bryant, D.J. and Edwards, A.D. 1996. Cerebral metabolism within 18 hours of birth asphyxia: a proton magnetic resonance spectroscopy study. Paediatric Research. 39 (4), pp. 584-590.

Anin vivo 13C magnetic resonance spectroscopic study of the relationship between diet and adipose tissue composition
Thomas, E.L., Frost, G.S., Barnard, M.L., Bryant, D.J., Taylor-Robinson, S.D., Simbrunner, J., Coutts, G.A., Burl, M., Bloom, S.R., Sales, K.D. and Bell, J.D. 1996. Anin vivo 13C magnetic resonance spectroscopic study of the relationship between diet and adipose tissue composition. Lipids. 31 (2), pp. 145-151.

Hepatic phosphorus-31 magnetic resonance spectroscopy in primary biliary cirrhosis and its relation to prognostic models
Jalan, R., Sargentoni, J., Coutts, G.A., Bell, J.D., Rolles, K., Burroughs, A.K. and Taylor-Robinson, S.D. 1996. Hepatic phosphorus-31 magnetic resonance spectroscopy in primary biliary cirrhosis and its relation to prognostic models. Gut. 39 (1), pp. 141-146.

α-aminophosphonate monoesters in one step
Bligh, S.W.A., McGrath, C.M., Failla, S. and Finocchiaro, P. 1996. α-aminophosphonate monoesters in one step. Phosphorus, Sulfur, and Silicon and the Related Elements. 118 (1), pp. 189-194.

Lanthanide and transition metal complexes of dialkyl alpha-hydroxyiminophosphonates
Bligh, S.W.A., Choi, N., Green, D.S.C., Hudson, H.R., McGrath, C.M., McPartlin, M. and Pianka, M. 1996. Lanthanide and transition metal complexes of dialkyl alpha-hydroxyiminophosphonates. Phosphorus, Sulfur, and Silicon and the Related Elements. 111 (1-4), p. 49.

Body fluid spectroscopic studies
Bell, J.D. and Sadler, P.J. 1996. Body fluid spectroscopic studies. in: Grant, D.M. and Harris, R.K. (ed.) Encyclopedia of nuclear magnetic resonance Chichester Wiley.

Dietary changes: observation by NMR spectroscopy
Bell, J.D. and Barnard, M.L. 1996. Dietary changes: observation by NMR spectroscopy. in: Grant, D.M. and Harris, R.K. (ed.) Encyclopedia of nuclear magnetic resonance Chichester Wiley.

Artificial neural network analysis of 1H NMR spectroscopic data from human plasma
Ala-Korpela, M., Hiltunen, Y. and Bell, J.D. 1996. Artificial neural network analysis of 1H NMR spectroscopic data from human plasma. Anticancer Research. 16 (3B), pp. 1473-1478.

Cirrhosis of the human liver: an in vitro 31P nuclear magnetic resonance study
Taylor-Robinson, S.D., Thomas, E.L., Sargentoni, J., Marcus, C.D., Davidson, B.R. and Bell, J.D. 1995. Cirrhosis of the human liver: an in vitro 31P nuclear magnetic resonance study. Biochimica et Biophysica Acta: Molecular Basis of Disease. 1272 (2), pp. 113-118.

Quantification of biomedical NMR data using artificial neural network analysis: lipoprotein lipid profiles from 1H NMR data of human plasma
Ala-Korpela, M., Hiltunen, Y. and Bell, J.D. 1995. Quantification of biomedical NMR data using artificial neural network analysis: lipoprotein lipid profiles from 1H NMR data of human plasma. NMR in Biomedicine. 8 (6), pp. 235-244.

MRI assessment of the blood-brain barrier in a hamster model of scrapie
Chung, Y.L., Williams, A., Beech, J.S., Williams, S.C.R., Bell, J.D., Cox, I.J. and Hope, J. 1995. MRI assessment of the blood-brain barrier in a hamster model of scrapie. Neurodegeneration. 4 (2), pp. 203-207.

Effect of functional grade and etiology on in vivo hepatic phosphorus-31 magnetic resonance spectroscopy in cirrhosis: Biochemical basis of spectral appearances
Menon, D.K., Sargentoni, J., Taylor-Robinson, S.D., Bell, J.D., Cox, I.J., Bryant, D.J., Coutts, G.A., Rolles, K., Burroughs, A.K. and Morgan, M.Y. 1995. Effect of functional grade and etiology on in vivo hepatic phosphorus-31 magnetic resonance spectroscopy in cirrhosis: Biochemical basis of spectral appearances. Hepatology. 21 (2), pp. 417-427.

Neutral gadolinium(III) complexes of bulky octadentate dtpa derivatives as potential contrast agents for magnetic resonance imaging
Bligh, S.W.A., Chowdhury, A.H.M.S., McPartlin, M. and Scowen, I.J. 1995. Neutral gadolinium(III) complexes of bulky octadentate dtpa derivatives as potential contrast agents for magnetic resonance imaging. Polyhedron. 14 (4), pp. 567-569.

Cerebral 31P MRS in patients with chronic hepatic encephalopathy
Taylor-Robinson, S.D., Bell, J.D., Sargentoni, J., Bryant, D.J., Mallalieu, R.J. and Morgan, M.Y. 1995. Cerebral 31P MRS in patients with chronic hepatic encephalopathy. in: Capocaccia, L., Merli, M. and Riggio, O. (ed.) Advances in hepatic encephalopathy and metabolic nitrogen exchange Hants CRC Press.

Teaching techniques in inorganic chemistry
Bligh, S.W.A., Conole, G. and McPartlin, M. 1995. Teaching techniques in inorganic chemistry. in: Variety in Chemistry Proceedings UK Physical Sciences Centre.

Cerebral Phosphorus-31 magnetic resonance spectroscopy in patients with chronic hepatic encephalopathy
Taylor-Robinson, S.D., Sargentoni, J., Mallalieu, R.J., Bell, J.D., Bryant, D.J., Coutts, G.A. and Morgan, M.Y. 1994. Cerebral Phosphorus-31 magnetic resonance spectroscopy in patients with chronic hepatic encephalopathy. Hepatology. 20 (5), pp. 1173-1178.

Utilization of uniformly labeled 13C-polyunsaturated fatty acids in the synthesis of long-chain fatty acids and cholesterol accumulating in the neonatal rat brain
Cunnane, S.C., Williams, S.C.R., Bell, J.D., Brookes, S., Craig, K., Iles, R.A. and Crawford, M.A. 1994. Utilization of uniformly labeled 13C-polyunsaturated fatty acids in the synthesis of long-chain fatty acids and cholesterol accumulating in the neonatal rat brain. Journal of Neurochemistry. 62 (6), pp. 2429-2436.

Synthesis, characterization and comparative study of aminophosphonate chelates of gadolinium(III) ions as magnetic resonance imaging contrast agents
Bligh, S.W.A., Harding, C.T., McEwen, A.B. and Sadler, P.J. 1994. Synthesis, characterization and comparative study of aminophosphonate chelates of gadolinium(III) ions as magnetic resonance imaging contrast agents. Polyhedron. 13 (12), pp. 1937-1943.

Effect of fish oil on cancer cachexia and host liver metabolism in rats with prostate tumours
Dagnelie, P.C., Bell, J.D., Williams, S.C.R., Bates, T.E., Abel, P.D. and Foster, C.S. 1994. Effect of fish oil on cancer cachexia and host liver metabolism in rats with prostate tumours. Lipids. 29 (3), pp. 195-203.

Synthesis of the first lanthanide complexes of dialkyl α-hydroxyiminophosphonates; ambivalent ligand bonding in the PrIII and NdIII complexes of diisopropyl α-hydroxyiminopropylphosphonate (L1), [PrL13Cl3] and [NdL12(NO3)3(H2O)]
Bligh, S.W.A., Choi, N., Hudson, H.R., McGrath, C.M. and McPartlin, M. 1994. Synthesis of the first lanthanide complexes of dialkyl α-hydroxyiminophosphonates; ambivalent ligand bonding in the PrIII and NdIII complexes of diisopropyl α-hydroxyiminopropylphosphonate (L1), [PrL13Cl3] and [NdL12(NO3)3(H2O)]. Journal of the Chemical Society, Dalton Transactions. 1994 (15), pp. 2335-2337.

First structural characterisation of an amino phosphonate monoester metal complex
Bligh, S.W.A., Choi, N., Failla, S., Finocchiaro, P., Il'yasov, A., Libertini, M., McGrath, C.M., McPartlin, M. and Woodroffe, T.M. 1994. First structural characterisation of an amino phosphonate monoester metal complex. Journal of the Chemical Society, Dalton Transactions. 1994 (22), pp. 3333-3334.

Metal-ion controlled helicity of an 18-membered hexaaza tetraamine macrocycle
Bligh, S.W.A., Choi, N., Evagorou, E.G., Li, W.S. and McPartlin, M. 1994. Metal-ion controlled helicity of an 18-membered hexaaza tetraamine macrocycle. Journal of the Chemical Society, Chemical Communications. 1994 (20), pp. 2399-2400.

Yttrium(III) and lanthanide(III) metal complexes of an 18-membered hexaaza tetraimine macrocycle. Crystal structure of the gadolinium(III) complex
Bligh, S.W.A., Choi, N., Cummins, W.J., Evagorou, E.G., Kelly, J.D. and McPartlin, M. 1994. Yttrium(III) and lanthanide(III) metal complexes of an 18-membered hexaaza tetraimine macrocycle. Crystal structure of the gadolinium(III) complex. Journal of the Chemical Society, Dalton Transactions. 1994 (23), pp. 3369-3376.

NMR studies of body fluids and tissue extracts
Bell, J.D., Preece, N.E. and Parkes, H.G. 1994. NMR studies of body fluids and tissue extracts. in: Gillies, R. (ed.) Nuclear magnetic resonance in physiology and biomedicine Oxford Pergamon.

In vivo fluorine-19 magnetic resonance spectroscopy of cerebral halothane in postoperative patients: preliminary results
Menon, D.K., Lockwood, G.G., Peden, C.J., Cox, I.J., Sargentoni, J., Bell, J.D., Coutts, G.A. and Whitwam, J.G. 1993. In vivo fluorine-19 magnetic resonance spectroscopy of cerebral halothane in postoperative patients: preliminary results. Magnetic Resonance in Medicine. 30 (6), pp. 680-684.

Transition metal complexes of dialkyl α-hydroxyiminophosphonates, a novel class of metal complexes
Bligh, S.W.A., Choi, N., Green, D.S.C., Hudson, H.R., McGrath, C.M., McPartlin, M. and Pianka, M. 1993. Transition metal complexes of dialkyl α-hydroxyiminophosphonates, a novel class of metal complexes. Polyhedron. 12 (23), pp. 2887-2890.

A 31P and 1H NMR investigation in vitro of normal and abnormal human liver
Bell, J.D., Cox, I.J., Sargentoni, J., Peden, C.J., Menon, D.K., Foster, C.S., Watanapa, P., Iles, R.A. and Urenjak, J. 1993. A 31P and 1H NMR investigation in vitro of normal and abnormal human liver. Biochimica et Biophysica Acta: Lipids and Lipid Metabolism. 1225 (1), pp. 71-77.

Altered phosphorylation status, phospholipid metabolism and gluconeogenesis in the host liver of rats with prostate cancer: a 31P magnetic resonance spectroscopy study
Dagnelie, P.C., Bell, J.D., Williams, S.C.R., Bates, T.E., Abel, P.D. and Foster, C.S. 1993. Altered phosphorylation status, phospholipid metabolism and gluconeogenesis in the host liver of rats with prostate cancer: a 31P magnetic resonance spectroscopy study. British Journal of Cancer. 67 (6), pp. 1303-1309.

The proton NMR spectrum in acute EAE: the significance of the change in the Cho:Cr ratio
Brenner, R.E., Munro, P.M.G., Williams, S.C.R., Bell, J.D., Barker, G.J., Landon, D.N., Hawkins, C.P. and McDonald, W.I. 1993. The proton NMR spectrum in acute EAE: the significance of the change in the Cho:Cr ratio. Magnetic Resonance in Medicine. 29 (6), pp. 737-745.

Effects of fish oil on phospholipid metabolism in human and rat liver studied by 31P NMR spectroscopy in vivo and in vitro
Dagnelie, P.C., Bell, J.D., Cox, I.J., Menon, D.K., Sargentoni, J., Coutts, G.A. and Williams, S.C.R. 1993. Effects of fish oil on phospholipid metabolism in human and rat liver studied by 31P NMR spectroscopy in vivo and in vitro. NMR in Biomedicine. 6 (2), pp. 157-162.

Potential of nuclear magnetic resonance spectroscopy for studies of N- fatty acid metabolism in plasma, liver and adipose tissues
Dagnelie, P.C., Bell, J.D., Barnard, M.L. and Williams, S.C.R. 1993. Potential of nuclear magnetic resonance spectroscopy for studies of N- fatty acid metabolism in plasma, liver and adipose tissues. in: Drevon, A., Baksaas, I. and Krokan, H.E. (ed.) Omega-3 fatty acids: metabolism and biological effects Basel, Switzerland Birkhauser Verlag. pp. 27-34

In vivo fatty acid analysis in humans and animals using carbon-13 nuclear magnetic resonance spectroscopy
Cunnane, S.C., Allman, T., Bell, J.D., Barnard, M.L., Coutts, G.A., Williams, S.C.R. and Iles, R.A. 1993. In vivo fatty acid analysis in humans and animals using carbon-13 nuclear magnetic resonance spectroscopy. Basic Life Sciences. 60, pp. 355-358.

Macrocyclic lanthanide complexes as potential contrast agents for NMR imaging
Bligh, S.W.A., Choi, N., Cummins, W.J., Evagorou, E.G., Kelly, J.D., McPartlin, M. and Parkes, H.G. 1993. Macrocyclic lanthanide complexes as potential contrast agents for NMR imaging. Journal of Inorganic Biochemistry. 51 (1-2), p. 438.

Synthesis and crystal structure of a novel hexaaza macrocyclic ligand with 2-hydroxy-3,5-dimethylbenzyl pendant arms and its gadolinium(III) complex
Bligh, S.W.A., Choi, N., Cummins, W.J., Evagorou, E.G., Kelly, J.D. and McPartlin, M. 1993. Synthesis and crystal structure of a novel hexaaza macrocyclic ligand with 2-hydroxy-3,5-dimethylbenzyl pendant arms and its gadolinium(III) complex. Journal of the Chemical Society, Dalton Transactions. 1993 (24), pp. 3829-3831.

NMR: a clinical approach
Bell, J.D. and Sadler, P.J. 1993. NMR: a clinical approach. Chemistry in Britain. 29, pp. 597-600.

Detection of aluminium (III) binding to citrate in human blood plasma by proton nuclear magnetic resonance spectroscopy
Bell, J.D., Kubal, G., Radulovic, S., Sadler, P.J. and Tucker, A. 1993. Detection of aluminium (III) binding to citrate in human blood plasma by proton nuclear magnetic resonance spectroscopy. The Analyst. 118, pp. 241-244.

Distortional isomerism in oxomolybdenum systems: the evidence re-evaluated
Bashall, A., Bligh, S.W.A., Edwards, A.J., McPartlin, M., Gibson, V.C. and Robinson, O.B. 1992. Distortional isomerism in oxomolybdenum systems: the evidence re-evaluated. Angewandte Chemie: International Edition in English. 31 (12), pp. 1607-1609.

Phosphorus-31 magnetic resonance spectroscopy of the human liver using chemical shift imaging techniques
Cox, I.J., Menon, D.K., Sargentoni, J., Bryant, D.J., Collins, A.G., Coutts, G.A., Iles, R.A., Bell, J.D., Benjamin, I.S., Gilbey, S., Hodgson, H.J.F. and Morgan, M.Y. 1992. Phosphorus-31 magnetic resonance spectroscopy of the human liver using chemical shift imaging techniques. Journal of Hepatology. 14 (2-3), pp. 265-275.

Effect of l-alanine infusion on 31P nuclear magnetic resonance spectra of normal human liver: towards biochemical pathology in vivo
Dagnelie, P.C., Menon, D.K., Cox, I.J., Bell, J.D., Sargentoni, J., Coutts, G.A., Urenjak, J. and Iles, R.A. 1992. Effect of l-alanine infusion on 31P nuclear magnetic resonance spectra of normal human liver: towards biochemical pathology in vivo. Clinical Science: an international journal of translational science and medicine. 83, pp. 183-190.

In vivo and in vitro31P magnetic resonance spectroscopy of focal hepatic malignancies
Cox, I.J., Bell, J.D., Peden, C.J., Iles, R.A., Foster, C.S., Watanapa, P. and Williamson, R.C.N. 1992. In vivo and in vitro31P magnetic resonance spectroscopy of focal hepatic malignancies. NMR in Biomedicine. 5 (3), pp. 114-120.

Synthesis and crystal structure of a gadolinium(III) complex of a tetraimine schiff-base macrocycle: a potential contrast agent for magnetic resonance imaging
Bligh, S.W.A., Choi, N., Evagorou, E.G., McPartlin, M., Cummins, W.J. and Kelly, J.D. 1992. Synthesis and crystal structure of a gadolinium(III) complex of a tetraimine schiff-base macrocycle: a potential contrast agent for magnetic resonance imaging. Polyhedron. 11 (19), pp. 2571-2573.

MRS characterisation of tissue and body fluids
Bell, J.D. 1992. MRS characterisation of tissue and body fluids. in: Textbook of magnetic resonance spectroscopy in biology and medicine: functional and pathological tissue characterisation Oxford Pergamon.

H-1-Nmr studies of reactions of copper complexes with human blood plasma and urine
Bligh, S.W.A., Boyle, H.A., McEwen, A.B., Sadler, P.J. and Woodham, R.H. 1992. H-1-Nmr studies of reactions of copper complexes with human blood plasma and urine. Biochemical Pharmacology. 43 (2), pp. 137-145.

In vivo detection of metabolic changes in a mouse model of scrapie using nuclear magnetic resonance spectroscopy
Bell, J.D., Cox, I.J., Williams, S.C.R., Belton, P.S., McConnell, I. and Hope, J. 1991. In vivo detection of metabolic changes in a mouse model of scrapie using nuclear magnetic resonance spectroscopy. Journal of General Virology. 72 (10), pp. 2419-2423.

Aluminium speciation: NMR studies of blood plasma, transferrin and citrate complexes
Bell, J.D., Evans, R.W., Kiang, W., Kubal, G., Radulovic, S., Sadler, P.J. and Williams, G. 1991. Aluminium speciation: NMR studies of blood plasma, transferrin and citrate complexes. Journal of Inorganic Biochemistry. 43 (2-3), p. 488.

Metabolites in the developing rat liver: a proton nuclear magnetic resonance spectroscopic study
Rafter, J.E.M., Bates, T.E., Bell, J.D. and Iles, R.A. 1991. Metabolites in the developing rat liver: a proton nuclear magnetic resonance spectroscopic study. Biochimica et Biophysica Acta: general subjects. 1074 (2), pp. 263-269.

Approaches to editing, assignment and interpretation of proton spectra
Gadian, D.G., Bates, T.E., Williams, S.R., Bell, J.D., Austin, S.J. and Connelly, A. 1991. Approaches to editing, assignment and interpretation of proton spectra. NMR in Biomedicine. 4 (2), pp. 85-89.

Use of paramagnetic chelated metal derivatives of polysaccharides and spin-labeled polysaccharides as contrast agents in magnetic resonance imaging
Bligh, S.W.A., Harding, C.T., Sadler, P.J., Bulman, R.A., Bydder, G.M., Pennock, J.M., Kelly, J.D., Clatham, I.A. and Marriott, J.A. 1991. Use of paramagnetic chelated metal derivatives of polysaccharides and spin-labeled polysaccharides as contrast agents in magnetic resonance imaging. Magnetic Resonance in Medicine. 17 (2), pp. 516-532.

Proton magnetic resonance spectroscopy in chronic renal failure
Menon, D.K., Cassidy, M.J.D., Baudouin, C., Sandford, R.N., Bell, J.D. and Sargentoni, J. 1991. Proton magnetic resonance spectroscopy in chronic renal failure. The Lancet. 337 (8735), pp. 244-245.

Nuclear magnetic resonance studies of blood plasma and urine from subjects with chronic renal failure: identification of trimethylamine-N-oxide
Bell, J.D., Lee, J.D., Lee, H.A., Sadler, P.J., Wilkie, D.R. and Woodham, R.H. 1991. Nuclear magnetic resonance studies of blood plasma and urine from subjects with chronic renal failure: identification of trimethylamine-N-oxide. Biochimica et Biophysica Acta: general subjects. 1096 (2), pp. 101-107.

Proton MR spectroscopy in herpes simplex encephalitis: assessment of neuronal loss
Menon, D.K., Sargentoni, J., Peden, C.J., Bell, J.D., Cox, I.J., Coutts, G.A., Baudouin, C. and Newman, C.G.H. 1990. Proton MR spectroscopy in herpes simplex encephalitis: assessment of neuronal loss. Journal of Computer Assisted Tomography. 14 (3), pp. 449-452.

31P Magnetic resonance spectroscopy of the human paediatric liver
Iles, R.A., Cox, I.J., Bell, J.D., Dubowitz, L.M.S., Cowan, F.M. and Bryant, D.J. 1990. 31P Magnetic resonance spectroscopy of the human paediatric liver. NMR in Biomedicine. 3 (2), pp. 90-94.

NMR studies of drug metabolism and disposition
Bell, J.D., Gadian, D.G. and Preece, N.E. 1990. NMR studies of drug metabolism and disposition. European Journal of Drug Metabolism and Pharmacokinetics. 15 (2), pp. 127-133.

Proton MR spectroscopy of the brain in infants
Peden, C.J., Cowan, F.M., Bryant, D.J., Sargentoni, J., Cox, I.J., Menon, D.K., Gadian, D.G., Bell, J.D. and Dubowitz, L.M.S. 1990. Proton MR spectroscopy of the brain in infants. Journal of Computer Assisted Tomography. 14 (6), pp. 886-894.

Proton MR spectroscopy of intracranial tumours: in vivo and in vitro studies
Gill, S.S., Thomas, D.G.T., van Bruggen, N., Gadian, D.G., Peden, C.J., Bell, J.D., Cox, I.J., Menon, D.K., Iles, R.A., Bryant, D.J. and Coutts, G.A. 1990. Proton MR spectroscopy of intracranial tumours: in vivo and in vitro studies. Journal of Computer Assisted Tomography. 14 (4), pp. 497-502.

Nuclear magnetic resonance and circular dichroism spectroscopic studies of copper complexation in blood plasma
Bligh, S.W.A., Drake, A.F. and Sadler, P.J. 1990. Nuclear magnetic resonance and circular dichroism spectroscopic studies of copper complexation in blood plasma. Biochemical Society Transactions. 18, pp. 999-1000.

NMR studies of body fluids
Bell, J.D., Brown, J.C.C. and Sadler, P.J. 1989. NMR studies of body fluids. NMR in Biomedicine. 2 (5-6), pp. 246-256.

1H NMR study of cerebral development in the rat
Bates, T.E., Williams, S.R., Gadian, D.G., Bell, J.D., Small, R.K. and Iles, R.A. 1989. 1H NMR study of cerebral development in the rat. NMR in Biomedicine. 2 (5-6), pp. 225-229.

Ultraviolet and magnetic-circular-diochroic spectroscopic studies of Gd(III) complexed with diethylenetriaminepentaacetic acid
Bligh, S.W.A., Drake, A.F. and Sadler, P.J. 1989. Ultraviolet and magnetic-circular-diochroic spectroscopic studies of Gd(III) complexed with diethylenetriaminepentaacetic acid. European Journal of Biochemistry. 181 (1), pp. 223-224.

Non-transferrin-bound iron in plasma or serum from patients with idiopathic hemochromatosis. Characterization by high performance liquid chromatography and nuclear magnetic resonance spectroscopy
Grootveld, M., Bell, J.D., Halliwell, B., Aruoma, O.I., Bomford, A. and Sadler, P.J. 1989. Non-transferrin-bound iron in plasma or serum from patients with idiopathic hemochromatosis. Characterization by high performance liquid chromatography and nuclear magnetic resonance spectroscopy. Journal of Biological Chemistry. 264 (8), pp. 4417-4422.

Characterization and invivo distribution of Tc-99m-labeled and In-111-labelled magnetite
Bligh, S.W.A., Sadler, P.J., Marriott, J.A., Latham, I.A. and Kelly, J.D. 1989. Characterization and invivo distribution of Tc-99m-labeled and In-111-labelled magnetite. Applied Radiation and Isotopes. 40, pp. 751-757.

Labels and contrast agents in biomedical magnetic resonance spectroscopy and imaging
Bligh, S.W.A. and Sadler, P.J. 1989. Labels and contrast agents in biomedical magnetic resonance spectroscopy and imaging. in: Dykes, J. and Delpy, D.T. (ed.) Clinical NMR spectroscopy York, England The Institute of Physical Sciences in Medicine. pp. 77-81

Nuclear magnetic resonance studies of body fluids: an overview
Bell, J.D. 1989. Nuclear magnetic resonance studies of body fluids: an overview. in: de Certaines, J.D. (ed.) Magnetic resonance spectroscopy of biofluids: a new tool in clinical biology London, U.K. World Scientific Publishing.

NMR-invisible lactate in blood plasma
Bell, J.D., Brown, J.C.C., Kubal, G. and Sadler, P.J. 1988. NMR-invisible lactate in blood plasma. FEBS Letters. 235 (1-2), pp. 81-86.

Factors affecting 1h NMR spectra of blood plasma: cancer, diet and freezing
Bell, J.D., Brown, J.C.C., Norman, R.E., Sadler, P.J. and Newell, D.R. 1988. Factors affecting 1h NMR spectra of blood plasma: cancer, diet and freezing. NMR in Biomedicine. 1 (2), pp. 90-94.

Metabolic profiling of body fluids by proton NMR: self-poisoning episodes with paracetamol (acetaminophen)
Bales, J.R., Bell, J.D., Nicholson, J.K., Sadler, P.J., Timbrell, J.A., Hughes, R.D., Bennett, P.N. and Williams, R. 1988. Metabolic profiling of body fluids by proton NMR: self-poisoning episodes with paracetamol (acetaminophen). Magnetic Resonance in Medicine. 6 (3), pp. 300-306.

NMR Spectroscopy of body fluids
Bell, J.D., Brown, J.C.C. and Sadler, P.J. 1988. NMR Spectroscopy of body fluids. Chemistry in Britain. 24, pp. 1021-1024.

Coordination chemistry in biological media: reactions of antitumor Pt(II) and Au(III) complexes with cell culture media
Bell, J.D., Norman, R.E. and Sadler, P.J. 1987. Coordination chemistry in biological media: reactions of antitumor Pt(II) and Au(III) complexes with cell culture media. Journal of Inorganic Biochemistry. 31 (4), pp. 241-246.

1H NMR studies of human blood plasma assignment of resonances for lipoproteins
Bell, J.D., Sadler, P.J., MacLeod, A.F., Turner, P.R. and La Ville, A. 1987. 1H NMR studies of human blood plasma assignment of resonances for lipoproteins. FEBS Letters. 219 (1), pp. 239-243.

Assignment of resonances for ‘acute-phase’ glycoproteins in high resolution proton NMR spectra of human blood plasma
Bell, J.D., Brown, J.C.C., Nicholson, J.K. and Sadler, P.J. 1987. Assignment of resonances for ‘acute-phase’ glycoproteins in high resolution proton NMR spectra of human blood plasma. FEBS Letters. 215 (2), pp. 311-315.

High resolution proton nuclear magnetic resonance studies of human cerebrospinal fluid
Bell, J.D., Brown, J.C.C., Sadler, P.J., MacLeod, A.F., Sönksen, P.H., Hughes, R.D. and Williams, R. 1987. High resolution proton nuclear magnetic resonance studies of human cerebrospinal fluid. Clinical Science: an international journal of translational science and medicine. 72, pp. 563-570.

1H NMR studies of urine during fasting: excretion of ketone bodies and acetylcarnitine
Bales, J.R., Bell, J.D., Nicholson, J.K. and Sadler, P.J. 1986. 1H NMR studies of urine during fasting: excretion of ketone bodies and acetylcarnitine. Magnetic Resonance in Medicine. 3 (6), pp. 849-856.

Permalink - https://westminsterresearch.westminster.ac.uk/item/9zv6q/withania-somnifera-root-extract-enhances-chemotherapy-through-priming


Share this
Tweet
Email