Title | Diagonal-SPRITE and its applications for in vivo imaging at high field |
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Authors | Protti, A., Herlihy, A.H., So, P.W., Tessier, J., Kalber, T. and Bell, J.D. |
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Abstract | Many solid or semi-solid tissues have ultra-short or short T2* components that make them virtually “invisible” to standard MRI techniques. For this reason, methods such as ultra-short echo time (UTE) techniques were developed to investigate and detect some of these short and ultra-short time components. Here we report on the development and implementation of a novel version of the Single Point Ramped Imaging with T1 Enhancement (SPRITE) technique in order to image mouse models. The method, called diagonal-SPRITE, was optimized within hardware limitations such as duty cycle and gradient strength at high field. Preliminary in vivo MR T2* value of organs of normal mouse models and related T2* maps were generated. In addition, the sequence was applied to highlight stomach short T2* after the application of a long T2* suppression pulse and to achieve a positive contrast in a SPIO-labelled cells experiment. |
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Journal | The Open Magnetic Resonance Journal |
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Journal citation | 2, pp. 1-7 |
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ISSN | 1874-7698 |
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Year | 2009 |
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Publisher | Bentham Open |
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Digital Object Identifier (DOI) | https://doi.org/10.2174/1874769800902010001 |
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Publication dates |
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Published | 2009 |
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