Machine Learning Classification of Females Susceptibility to Visceral Fat Associated Diseases

Aldraimli, M., Soria, D., Parkinson, J., Whitcher, B., Thomas, E.L., Bell, J.D., Chaussalet, T.J. and Dwek, M. 2019. Machine Learning Classification of Females Susceptibility to Visceral Fat Associated Diseases. MEDICON 2019: XV Mediterranean Conference on Medical and Biological Engineering and Computing. Coimbra, Portugal 26 - 28 Sep 2019 Springer. https://doi.org/10.1007/978-3-030-31635-8_81

TitleMachine Learning Classification of Females Susceptibility to Visceral Fat Associated Diseases
AuthorsAldraimli, M., Soria, D., Parkinson, J., Whitcher, B., Thomas, E.L., Bell, J.D., Chaussalet, T.J. and Dwek, M.
TypeConference paper
Abstract

The problem of classifying subjects into risk categories is a common challenge in medical research. Machine Learning (ML) methods are widely used in the areas of risk prediction and classification. The primary objective of these algorithms is to predict dichotomous responses (e.g. healthy/at risk) based on several features. Similarly to statistical inference models, also ML models are subject to the common problem of class imbalance. Therefore, they are affected by the majority class increasing the false-negative rate.
In this paper, we built and evaluated eighteen ML models classifying approximately 4300 female participants from the UK Biobank into three categorical risk statuses based on responses for the discretised visceral adipose tissue values from magnetic resonance imaging. We also examined the effect of sampling techniques on classification modelling when dealing with class imbalance.
Results showed that the use of sampling techniques had a significant impact. They not only drove an improvement in predicting patients risk status but also facilitated an increase in the information contained within each variable. Based on domain experts criteria, the three best models for classification were finally identified.
These encouraging results will guide further developments of classification models for predicting visceral adipose tissue without the need for a costly scan.

KeywordsSupervised Learning
Imbalanced Data
UK Biobank
Random Under-Sampling
Synthetic Minority Over-Sampling Technique
Visceral Adipose Tissue
Year2019
ConferenceMEDICON 2019: XV Mediterranean Conference on Medical and Biological Engineering and Computing
PublisherSpringer
Accepted author manuscript
Publication dates
Published25 Sep 2019
JournalIFMBE Proceedings
Journal citation76, pp. 679-693
ISSN1680-0737
ISBN9783030316341
9783030316358
Digital Object Identifier (DOI)https://doi.org/10.1007/978-3-030-31635-8_81

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Morra, Anna, Escala-Garcia, Maria, Beesley, Jonathan, Keeman, Renske, Canisius, Sander, Ahearn, Thomas U, Andrulis, Irene L, Anton-Culver, Hoda, Arndt, Volker, Auer, Paul L, Augustinsson, Annelie, Beane Freeman, Laura E, Becher, Heiko, Beckmann, Matthias W, Behrens, Sabine, Bojesen, Stig E, Bolla, Manjeet K, Brenner, Hermann, Brüning, Thomas, Buys, Saundra S, Caan, Bette, Campa, Daniele, Canzian, Federico, Castelao, Jose E, Chang-Claude, Jenny, Chanock, Stephen J, Cheng, Ting-Yuan David, Clarke, Christine L, Colonna, Sarah V, Couch, Fergus J, Cox, Angela, Cross, Simon S, Czene, Kamila, Daly, Mary B, Dennis, Joe, Dörk, T., Dossus, Laure, Dunning, Alison M, Dwek, Miriam, Eccles, Diana M, Ekici, Arif B, Eliassen, A Heather, Eriksson, Mikael, Evans, D Gareth, Fasching, Peter A, Flyger, Henrik, Fritschi, Lin, Gago-Dominguez, Manuela, García-Sáenz, José A, Giles, Graham G, Grip, Mervi, Guénel, Pascal, Gündert, Melanie, Hahnen, Eric, Haiman, Christopher A, Håkansson, Niclas, Hall, Per, Hamann, Ute, Hart, Steven N, Hartikainen, Jaana M, Hartmann, Arndt, He, Wei, Hooning, Maartje J, Hoppe, Reiner, Hopper, John L, Howell, Anthony, Hunter, David J, Jager, Agnes, Jakubowska, Anna, Janni, Wolfgang, John, Esther M, Jung, Audrey Y, Kaaks, Rudolf, Keupers, Machteld, Kitahara, Cari M, Koutros, Stella, Kraft, Peter, Kristensen, Vessela N, Kurian, Allison W, Lacey, James V, Lambrechts, Diether, Le Marchand, Loic, Lindblom, Annika, Linet, Martha, Luben, Robert N, Lubiński, Jan, Lush, Michael, Mannermaa, Arto, Manoochehri, Mehdi, Margolin, Sara, Martens, John W M, Martinez, Maria Elena, Mavroudis, Dimitrios, Michailidou, Kyriaki, Milne, Roger L, Mulligan, Anna Marie, Muranen, Taru A, Nevanlinna, Heli, Newman, W., Nielsen, Sune F, Nordestgaard, Børge G, Olshan, Andrew F, Olsson, Håkan, Orr, Nick, Park-Simon, Tjoung-Won, Patel, Alpa V, Peissel, Bernard, Peterlongo, Paolo, Plaseska-Karanfilska, Dijana, Prajzendanc, Karolina, Prentice, Ross, Presneau, Nadege, Rack, Brigitte, Rennert, Gad, Rennert, Hedy S, Rhenius, Valerie, Romero, A., Roylance, Rebecca, Ruebner, Matthias, Saloustros, Emmanouil, Sawyer, Elinor J, Schmutzler, Rita K, Schneeweiss, Andreas, Scott, Christopher, Shah, Mitul, Smichkoska, Snezhana, Southey, Melissa C, Stone, J., Surowy, Harald, Swerdlow, Anthony J, Tamimi, Rulla M, Tapper, William J, Teras, Lauren R, Terry, Mary Beth, Tollenaar, Rob A E M, Tomlinson, Ian, Troester, Melissa A, Truong, Thérèse, Vachon, Celine M, Wang, Qin, Hurson, Amber N, Winqvist, Robert, Wolk, Alicja, Ziogas, Argyrios, Brauch, Hiltrud, García-Closas, Montserrat, Pharoah, Paul D P, Easton, Douglas F, Chenevix-Trench, Georgia and Schmidt, M. 2021. Association of germline genetic variants with breast cancer-specific survival in patient subgroups defined by clinic-pathological variables related to tumor biology and type of systemic treatment. Breast cancer research : BCR. 23 (1), p. 86 86. https://doi.org/10.1186/s13058-021-01450-7

Breast Cancer Risk Factors and Survival by Tumor Subtype: Pooled Analyses from the Breast Cancer Association Consortium
Morra, Anna, Jung, Audrey Y., Behrens, S., Keeman, R., Ahearn, T., Anton-Culver, Hoda, Arndt, V., Augustinsson, A., Auvinen, Päivi K., Beane Freeman, Laura E., Becher, Heiko, Beckmann, Matthias W., Blomqvist, Carl, Bojesen, Stig E., Bolla, Manjeet K., Brenner, H., Briceno, Ignacio, Brucker, Sara Y., Camp, N., Campa, Daniele, Canzian, F., Castelao, Jose E., Chanock, Stephen J., Choi, Ji-Yeob, Clarke, Christine L., Couch, Fergus J., Cox, A., Cross, Simon S., Czene, Kamila, Dörk, Thilo, Dunning, A., Dwek, Miriam, Easton, Douglas F., Eccles, Diana M., Egan, Kathleen M., Evans, D., Fasching, P., Flyger, Henrik, Gago-Dominguez, M., Gapstur, Susan M., Garcia-Saenz, J., Gaudet, M., Giles, G., Grip, Mervi, Guénel, P., Haiman, Christopher A., Håkansson, Niclas, Hall, P., Hamann, Ute, Han, Sileny N., Hart, S., Hartman, M., Heyworth, Jane S., Hoppe, Reiner, Hopper, John L., Hunter, David J., Ito, H., Jager, A., Jakimovska, Milena, Jakubowska, A., Janni, W., Kaaks, R., Kang, Daehee, Middha Kapoor, P., Kitahara, Cari M., Koutros, S., Kraft, Peter, Kristensen, Vessela N., Lacey, James V., Lambrechts, D., Le Marchand, Loic, Li, J., Lindblom, Annika, Lubiński, Jan, Lush, Michael, Mannermaa, Arto, Manoochehri, Mehdi, Margolin, Sara, Mariapun, Shivaani, Matsuo, K., Mavroudis, Dimitrios, Milne, R., Muranen, T., Newman, W., Noh, Dong-Young, Nordestgaard, Børge G., Obi, Nadia, Olshan, Andrew F., Olsson, Håkan, Park-Simon, T., Petridis, Christos, Pharoah, P., Plaseska-Karanfilska, Dijana, Presneau, Nadege, Rashid, Muhammad U., Rennert, G., Rennert, H., Rhenius, V., Romero, A., Saloustros, E., Sawyer, Elinor J., Schneeweiss, A., Schwentner, Lukas, Scott, C., Shah, Mitul, Shen, Chen-Yang, Shu, Xiao-Ou, Southey, M., Stram, D., Tamimi, R., Tapper, William, Tollenaar, Rob A.E.M., Tomlinson, I., Torres, D., Troester, Melissa A., Truong, Thérèse, Vachon, C., Wang, Qin, Wang, Sophia S., Williams, Justin A., Winqvist, Robert, Wolk, A., Wu, Anna H., Yoo, Keun-Young, Yu, Jyh-Cherng, Zheng, Wei, Ziogas, A., Yang, Xiaohong R., Eliassen, A. Heather, Holmes, M., Garcia-Closas, M., Teo, S., Schmidt, M. and Chang-Claude, J. 2021. Breast Cancer Risk Factors and Survival by Tumor Subtype: Pooled Analyses from the Breast Cancer Association Consortium. Cancer Epidemiology, Biomarkers and Prevention. 30 (4), pp. 623-642. https://doi.org/10.1158/1055-9965.epi-20-0924

SARS-CoV-2 and EBV; the cost of a second mitochondrial "whammy"?
Nunn, A., Guy, G., Botchway, S.W. and Bell, J.D. 2021. SARS-CoV-2 and EBV; the cost of a second mitochondrial "whammy"? Immunity & Ageing. 18 (1), pp. 40-44. https://doi.org/10.1186/s12979-021-00252-x

Adipose tissue dysfunction, inflammation, and insulin resistance alternative pathways to cardiac remodelling in schizophrenia. A multimodal, case-control study
Osimo, E.F., Sweeney, M., de Marvao, A., Berry, A., Statton, B., Perry, B.I., Pillinger, T., Whitehurst, T., Cook, S.A., O’Regan, D.P., Thomas, E.L. and Howes, O.D. 2021. Adipose tissue dysfunction, inflammation, and insulin resistance alternative pathways to cardiac remodelling in schizophrenia. A multimodal, case-control study. Translational Psychiatry. 11 614. https://doi.org/10.1038/s41398-021-01741-9

A systematic review of the applications of Expert Systems (ES) and machine learning (ML) in clinical urology.
Salem, H., Soria, D., Lund, J. and Awwad, A. 2021. A systematic review of the applications of Expert Systems (ES) and machine learning (ML) in clinical urology. BMC Medical Informatics and Decision Making. 21 (1) 223. https://doi.org/10.1186/s12911-021-01585-9

Mendelian randomisation study of smoking exposure in relation to breast cancer risk.
Park, H., Neumeyer, Sonja, Michailidou, Kyriaki, Bolla, Manjeet K, Wang, Qin, Dennis, J., Ahearn, Thomas U, Andrulis, Irene L, Anton-Culver, Hoda, Antonenkova, Natalia N, Arndt, Volker, Aronson, Kristan J, Augustinsson, A., Baten, Adinda, Beane Freeman, Laura E, Becher, Heiko, Beckmann, Matthias W, Behrens, Sabine, Benitez, Javier, Bermisheva, Marina, Bogdanova, Natalia V, Bojesen, Stig E, Brauch, Hiltrud, Brenner, H., Brucker, Sara Y, Burwinkel, Barbara, Campa, Daniele, Canzian, F., Castelao, Jose E, Chanock, Stephen J, Chenevix-Trench, Georgia, Clarke, Christine L, NBCS Collaborators, Conroy, Don M, Couch, Fergus J, Cox, A., Cross, Simon S, Czene, Kamila, Daly, Mary B, Devilee, P., Dörk, Thilo, Dos-Santos-Silva, Isabel, Dwek, Miriam, Eccles, Diana M, Eliassen, A Heather, Engel, Christoph, Eriksson, Mikael, Evans, D Gareth, Fasching, P., Flyger, Henrik, Fritschi, Lin, García-Closas, Montserrat, García-Sáenz, José A, Gaudet, Mia M, Giles, Graham G, Glendon, Gord, Goldberg, Mark S, Goldgar, David E, González-Neira, Anna, Grip, Mervi, Guénel, Pascal, Hahnen, Eric, Haiman, Christopher A, Håkansson, Niclas, Hall, Per, Hamann, Ute, Han, Sileny, Harkness, E., Hart, S., He, Wei, Heemskerk-Gerritsen, B., Hopper, John L, Hunter, David J, ABCTB Investigators, kConFab Investigators, Jager, Agnes, Jakubowska, A., John, Esther M, Jung, Audrey, Kaaks, Rudolf, Middha Kapoor, P., Keeman, Renske, Khusnutdinova, Elza, Kitahara, Cari M, Koppert, Linetta B, Koutros, Stella, Kristensen, Vessela N, Kurian, A., Lacey, James, Lambrechts, Diether, Le Marchand, Loic, Lo, Wing-Yee, Lubiński, Jan, Mannermaa, Arto, Manoochehri, Mehdi, Margolin, Sara, Martinez, Maria Elena, Mavroudis, Dimitrios, Meindl, Alfons, Menon, Usha, Milne, Roger L, Muranen, Taru A, Nevanlinna, Heli, Newman, W., Nordestgaard, Børge G, Offit, Kenneth, Olshan, Andrew F, Olsson, Håkan, Park-Simon, Tjoung-Won, Peterlongo, P., Peto, J., Plaseska-Karanfilska, Dijana, Presneau, Nadege, Radice, Paolo, Rennert, Gad, Rennert, Hedy S, Romero, Atocha, Saloustros, Emmanouil, Sawyer, E., Schmidt, Marjanka K, Schmutzler, Rita K, Schoemaker, Minouk J, Schwentner, Lukas, Scott, C., Shah, Mitul, Shu, Xiao-Ou, Simard, Jacques, Smeets, A., Southey, Melissa C, Spinelli, John J, Stevens, Victoria, Swerdlow, Anthony J, Tamimi, Rulla M, Tapper, William J, Taylor, Jack A, Terry, Mary Beth, Tomlinson, I., Troester, Melissa A, Truong, T., Vachon, Celine M, van Veen, Elke M, Vijai, Joseph, Wang, Sophia, Wendt, Camilla, Winqvist, Robert, Wolk, Alicja, Ziogas, Argyrios, Dunning, Alison M, Pharoah, P., Easton, Douglas F, Zheng, Wei, Kraft, Peter and Chang-Claude, Jenny 2021. Mendelian randomisation study of smoking exposure in relation to breast cancer risk. British Journal of Cancer. https://doi.org/10.1038/s41416-021-01432-8

Mass Univariate Regression Analysis for Three-Dimensional Liver Image-Derived Phenotypes
Thanaj, M., Basty, N., Liu, Y., Cule, M., Sorokin, E., Thomas, E.L., Bell, J.D. and Whitcher, B. 2021. Mass Univariate Regression Analysis for Three-Dimensional Liver Image-Derived Phenotypes. Annual Conference on Medical Image Understanding and Analysis. University of Oxford 12 - 14 Jul 2021 Springer. https://doi.org/10.1007/978-3-030-80432-9_13

A Data Science Approach for Early-Stage Prediction of Patient’s Susceptibility to Acute Side Effects of Advanced Radiotherapy
Aldraimli, M., Soria, D., Grishchuck, D., Ingram, S., Lyon, R., Mistry, A., Oliveira, J., Samuel, R., Shelley, L.E.A., Osman, S., Dwek, M., Azria, D., Chang-Claude, J., Gutiérrez-Enríquez, S., De Santis, M.C., Rosenstein, B.S., De Ruysscher, D., Sperk, E., Symonds, R.P., Stobart, H., Vega, A., Veldeman, L., Webb, A, Christopher, J.T., West, C.M., Rattay, T., REQUITE consortium and Chaussalet, T.J. 2021. A Data Science Approach for Early-Stage Prediction of Patient’s Susceptibility to Acute Side Effects of Advanced Radiotherapy. Computers in Biology and Medicine. 135 104624. https://doi.org/10.1016/j.compbiomed.2021.104624

Functional annotation of the 2q35 breast cancer risk locus implicates a structural variant in influencing activity of a long-range enhancer element.
Baxter, Joseph S, Johnson, Nichola, Tomczyk, Katarzyna, Gillespie, Andrea, Maguire, Sarah, Brough, Rachel, Fachal, Laura, Michailidou, Kyriaki, Bolla, Manjeet K, Wang, Qin, Dennis, Joe, Ahearn, Thomas U, Andrulis, Irene L, Anton-Culver, Hoda, Antonenkova, Natalia N, Arndt, Volker, Aronson, Kristan J, Augustinsson, Annelie, Becher, Heiko, Beckmann, Matthias W, Behrens, Sabine, Benitez, Javier, Bermisheva, Marina, Bogdanova, Natalia V, Bojesen, Stig E, Brenner, Hermann, Brucker, Sara Y, Cai, Qiuyin, Campa, Daniele, Canzian, Federico, Castelao, Jose E, Chan, Tsun L, Chang-Claude, Jenny, Chanock, Stephen J, Chenevix-Trench, Georgia, Choi, Ji-Yeob, Clarke, Christine L, NBCS Collaborators, Colonna, Sarah, Conroy, Don M, Couch, Fergus J, Cox, Angela, Cross, Simon S, Czene, Kamila, Daly, Mary B, Devilee, Peter, Dörk, Thilo, Dossus, Laure, Dwek, Miriam, Eccles, Diana M, Ekici, Arif B, Eliassen, A Heather, Engel, Christoph, Fasching, Peter A, Figueroa, Jonine, Flyger, Henrik, Gago-Dominguez, Manuela, Gao, Chi, García-Closas, Montserrat, García-Sáenz, José A, Ghoussaini, Maya, Giles, Graham G, Goldberg, Mark S, González-Neira, Anna, Guénel, Pascal, Gündert, Melanie, Haeberle, Lothar, Hahnen, Eric, Haiman, Christopher A, Hall, Per, Hamann, Ute, Hartman, Mikael, Hatse, Sigrid, Hauke, Jan, Hollestelle, Antoinette, Hoppe, Reiner, Hopper, John L, Hou, Ming-Feng, kConFab Investigators, ABCTB Investigators, Ito, Hidemi, Iwasaki, Motoki, Jager, Agnes, Jakubowska, Anna, Janni, Wolfgang, John, Esther M, Joseph, Vijai, Jung, Audrey, Kaaks, Rudolf, Kang, Daehee, Keeman, Renske, Khusnutdinova, Elza, Kim, Sung-Won, Kosma, Veli-Matti, Kraft, Peter, Kristensen, Vessela N, Kubelka-Sabit, Katerina, Kurian, Allison W, Kwong, Ava, Lacey, James V, Lambrechts, Diether, Larson, Nicole L, Larsson, Susanna C, Le Marchand, Loic, Lejbkowicz, Flavio, Li, Jingmei, Long, Jirong, Lophatananon, Artitaya, Lubiński, Jan, Mannermaa, Arto, Manoochehri, Mehdi, Manoukian, Siranoush, Margolin, Sara, Matsuo, Keitaro, Mavroudis, Dimitrios, Mayes, Rebecca, Menon, Usha, Milne, Roger L, Mohd Taib, Nur Aishah, Muir, Kenneth, Muranen, Taru A, Murphy, Rachel A, Nevanlinna, Heli, O'Brien, Katie M, Offit, Kenneth, Olson, Janet E, Olsson, Håkan, Park, Sue K, Park-Simon, Tjoung-Won, Patel, Alpa V, Peterlongo, Paolo, Peto, Julian, Plaseska-Karanfilska, Dijana, Presneau, Nadege, Pylkäs, Katri, Rack, Brigitte, Rennert, Gad, Romero, Atocha, Ruebner, Matthias, Rüdiger, Thomas, Saloustros, Emmanouil, Sandler, Dale P, Sawyer, Elinor J, Schmidt, Marjanka K, Schmutzler, Rita K, Schneeweiss, Andreas, Schoemaker, Minouk J, Shah, Mitul, Shen, Chen-Yang, Shu, Xiao-Ou, Simard, Jacques, Southey, Melissa C, Stone, Jennifer, Surowy, Harald, Swerdlow, Anthony J, Tamimi, Rulla M, Tapper, William J, Taylor, Jack A, Teo, Soo Hwang, Teras, Lauren R, Terry, Mary Beth, Toland, Amanda E, Tomlinson, Ian, Truong, Thérèse, Tseng, Chiu-Chen, Untch, Michael, Vachon, Celine M, van den Ouweland, Ans M W, Wang, Sophia S, Weinberg, Clarice R, Wendt, Camilla, Winham, Stacey J, Winqvist, Robert, Wolk, Alicja, Wu, Anna H, Yamaji, Taiki, Zheng, Wei, Ziogas, Argyrios, Pharoah, Paul D P, Dunning, Alison M, Easton, Douglas F, Pettitt, Stephen J, Lord, Christopher J, Haider, Syed, Orr, Nick and Fletcher, Olivia 2021. Functional annotation of the 2q35 breast cancer risk locus implicates a structural variant in influencing activity of a long-range enhancer element. American Journal of Human Genetics. 108, pp. 1190-1203. https://doi.org/10.1016/j.ajhg.2021.05.013

Genetic architecture of 11 organ traits derived from abdominal MRI using deep learning.
Liu, Y., Basty, N., Whitcher, B., Bell, J.D., Sorokin, E., van Bruggen, Nick, Thomas, E.L. and Cule, M. 2021. Genetic architecture of 11 organ traits derived from abdominal MRI using deep learning. eLife. 10. https://doi.org/10.7554/elife.65554

3D Deep Learning for Anatomical Structure Segmentation in Multiple Imaging Modalities
Villarini, B., Asaturyan, H., Kurugol, S., Afacan, O., Bell, J.D. and Thomas, E.L. 2021. 3D Deep Learning for Anatomical Structure Segmentation in Multiple Imaging Modalities. O'Conner, L. (ed.) 34th IEEE CBMS International Symposium on Computer-Based Medical Systems. Online Event 07 - 09 Jun 2021 IEEE . https://doi.org/10.1109/CBMS52027.2021.00066

Incorporating spatial context into remaining-time predictive process monitoring
Ogunbiyi, Niyi, Basukoski, Artie and Chaussalet, Thierry 2021. Incorporating spatial context into remaining-time predictive process monitoring. 36th Annual ACM Symposium on Applied Computing. Virtual Event Republic of Korea 22 - 26 Mar 2021 ACM. https://doi.org/10.1145/3412841.3441933

Genetic evidence for different adiposity phenotypes and their opposing influence on ectopic fat and risk of cardiometabolic disease
Martin, S., Cule, M, Basty, N., Tyrrell, J., Beaumont, R.N., Wood, A.R., Frayling, T., Sorokin, E., Whitcher, B., Liu, Y., Bell, J.D., Thomas, E.L. and Yaghootkar, H. 2021. Genetic evidence for different adiposity phenotypes and their opposing influence on ectopic fat and risk of cardiometabolic disease. Diabetes. 70 (8), pp. 1843-1856. https://doi.org/10.2337/db21-0129

Mitochondrial Function as a Potential Tool for Assessing Function, Quality and Adulteration in Medicinal Herbal Teas
Woodley, S., Mould, R., Sahuri Arisoylu, M., Kalampouka, I., Booker, A. and Bell, J.D. 2021. Mitochondrial Function as a Potential Tool for Assessing Function, Quality and Adulteration in Medicinal Herbal Teas. Frontiers in Pharmacology. 12 660938. https://doi.org/10.3389/fphar.2021.660938

Acetate induces growth arrest in colon cancer cells through modulation of mitochondrial function
Sahuri Arisoylu, M., Mould, R., Shinjyo, N., Bligh, S.W.A., Nunn, A., Guy, G., Thomas, E.L. and Bell, J.D. 2021. Acetate induces growth arrest in colon cancer cells through modulation of mitochondrial function. Frontiers in Nutrition: Nutrition and Metabolism. 8 588466. https://doi.org/10.3389/fnut.2021.588466

Cannabidiol modulates mitochondrial redox and dynamics in MCF7 cancer cells: a study using fluorescence lifetime imaging microscopy of NAD(P)H
Mould, R., Botchway, S, Parkinson, J., Thomas, E.L., Guy, G., Bell, J.D. and Nunn, A. 2021. Cannabidiol modulates mitochondrial redox and dynamics in MCF7 cancer cells: a study using fluorescence lifetime imaging microscopy of NAD(P)H. Frontiers in Molecular Biosciences. 8 630107. https://doi.org/10.3389/fmolb.2021.630107

An Exploration of Ethical Decision Making with Intelligence Augmentation
Ogunbiyi, O., Basukoski, A. and Chaussalet, T.J. 2021. An Exploration of Ethical Decision Making with Intelligence Augmentation. Social Sciences. 10 (2) 57. https://doi.org/10.3390/socsci10020057

Carbon Footprints in Emergency Departments: A Simulation-Optimization Analysis
Vali, M., Salimifard, K. and Chaussalet, T. 2021. Carbon Footprints in Emergency Departments: A Simulation-Optimization Analysis. in: Masmoudi M., Jarboui B. and Siarry P. (ed.) Operations Research and Simulation in Healthcare Springer. pp. 193-207

Clinical relevance assessment of animal preclinical research (RAA) tool: development and explanation.
Gurusamy, K., Moher, D., Loizidou, M., Ahmed, Irfan, Avey, M., Barron, Carly C, Davidson, Brian, Dwek, M., Gluud, C., Jell, G., Katakam, Kiran, Montroy, Joshua, McHugh, T., Osborne, N., Ritskes-Hoitinga, M., van Laarhoven, Kees, Vollert, Jan and Lalu, Manoj 2021. Clinical relevance assessment of animal preclinical research (RAA) tool: development and explanation. PeerJ . 9 e10673. https://doi.org/10.7717/peerj.10673

Processes Underlying Glycemic Deterioration in Type 2 Diabetes: An IMI DIRECT Study
Bizzotto, R., Jennison, C., Jones, A., Kurbasic, A., Kennedy, G., Bell, J.D., Thomas, E.L., Frost, G., Eriksen, R., Koivula, R., Brage, S., Kaye, J., Hattersley, A., Heggie, A., McEvoy, D., Hart, L.M., Beulens, J.W., Elders, P., Musholt, P.B., Ridderstråle, M., Hansen, T., Allin, K., Hansen, T., Vestergaard, H., Lundgaard, A.T., Thomsen, H.S., Masi, F., Tsirigos, K.D., Brunak, S., Viñuela, A., Mahajan, A., McDonald, T.J., Kokkola, T., Forgie, I., Giordano, G.N., Pavo, I., Ruetten, H., Dermitzakis, E., McCarthy, M., Pedersen, O., Schwenk, J., Adamski, J., Franks, P., Walker, M., Pearson, E. and Mari, A. 2021. Processes Underlying Glycemic Deterioration in Type 2 Diabetes: An IMI DIRECT Study. Diabetes Care. 44 (2), pp. 511-518. https://doi.org/10.2337/dc20-1567

Germline HOXB13 mutations p.G84E and p.R217C do not confer an increased breast cancer risk
Liu, J., Prager-van der Smissen, W.J.C., Collée, J.M., Bolla, M.K., Wang, Q., Michailidou, K., Dennis, J., Ahearn, T.U., Aittomäki, K., Ambrosone, C.B., Andrulis, I.L., Hollestelle, A. and Dwek, M. 2020. Germline HOXB13 mutations p.G84E and p.R217C do not confer an increased breast cancer risk. Scientific Reports. 10 9688. https://doi.org/10.1038/s41598-020-65665-y

Investigating the Diffusion of Workload-Induced Stress—A Simulation Approach
Ogunbiyi, O., Basukoski, A. and Chaussalet, T.J. 2020. Investigating the Diffusion of Workload-Induced Stress—A Simulation Approach. Information. 12 (1) 11. https://doi.org/10.3390/info12010011

SARS-CoV-2 and mitochondrial health: implications of lifestyle and ageing
Nunn, A.V.W., Guy, G.W., Brysch, W., Botchway, S.W., Frasch, W., Calabrese, E.J. and Bell, J.D. 2020. SARS-CoV-2 and mitochondrial health: implications of lifestyle and ageing. Immunity & Ageing. 17 33 (2020). https://doi.org/10.1186/s12979-020-00204-x

Large‑scale analysis of iliopsoas muscle volumes in the UK Biobank
Fitzpatrick, J., Basty, N., Cule, M., Liu, Y., Bell, J.D., Thomas, E.L. and Whitcher, B. 2020. Large‑scale analysis of iliopsoas muscle volumes in the UK Biobank. Scientific Reports. 10 20215. https://doi.org/10.1038/s41598-020-77351-0

Investigating Social Contextual Factors in Remaining-Time Predictive Process Monitoring—A Survival Analysis Approach
Ogunbiyi, N., Basukoski, A. and Chaussalet, T.J. 2020. Investigating Social Contextual Factors in Remaining-Time Predictive Process Monitoring—A Survival Analysis Approach. Algorithms. 13 (11), p. e267. https://doi.org/10.3390/a13110267

Normalized indices derived from visceral adipose mass assessed by MRI and their correlation with markers for insulin resistance and prediabetes
Machann, J., Stefan, N., Wagner, R., Fritsche, A., Bell, J.D., Whitcher, B., Häring, H.U., Birkenfeld, A., Nikolaou, K., Schick, F. and Thomas, E.L. 2020. Normalized indices derived from visceral adipose mass assessed by MRI and their correlation with markers for insulin resistance and prediabetes. Nutrients. 12 (7) 2064. https://doi.org/10.3390/nu12072064

Cancer cells grown in 3D under fluid flow exhibit an aggressive phenotype and reduced responsiveness to the anti-cancer treatment doxorubicin.
Azimi, T., Loizidou, M. and Dwek, M. 2020. Cancer cells grown in 3D under fluid flow exhibit an aggressive phenotype and reduced responsiveness to the anti-cancer treatment doxorubicin. Scientific Reports. 10 (1) 12020. https://doi.org/10.1038/s41598-020-68999-9

Predicting and elucidating the etiology of fatty liver disease: A machine learning modeling and validation study in the IMI DIRECT cohorts
Atabaki-Pasdar, N., Ohlsson, M., Viñuela, A., Frau, F., Pomares-Millan, H., Haid, M., Jones, A., Thomas, E.L., Koivula, R., Kurbasic, A., Mutie, P., Fitipaldi, H., Fernandez, J., Dawed, A., Giordano, G., Forgie, I., McDonald, T., Rutters, F., Cederberg, H., Chabanova, E., Dale, M., Masi, F., Thomas, C., Allin, K., Hansen, T., Heggie, A., Hong, M., Elders, P., Kennedy, G., Kokkola, T., Pedersen, H., Mahajan, A., McEvoy, D., Pattou, F., Raverdy, V., Häussler, R., Sharma, S., Thomsen, H., Vangipurapu, J., Vestergaard, H., ‘t Hart, L., Adamski, J., Musholt, P., Brage, S., Brunak, S., Dermitzakis, E., Frost, G., Hansen, T., Laakso, M., Pedersen, O., Ridderstråle, M., Ruetten, H., Hattersley, A., Walker, M., Beulens, J., Mari, A., Schwenk, J., Gupta, R., McCarthy, M., Pearson, E., Bell, J.D., Pavo, I. and Franks, P. 2020. Predicting and elucidating the etiology of fatty liver disease: A machine learning modeling and validation study in the IMI DIRECT cohorts. PLoS Medicine. 17 (6) e1003149. https://doi.org/10.1371/journal.pmed.1003149

Dietary metabolite profiling brings new insight into the relationship between nutrition and metabolic risk: An IMI Direct study
Eriksen, R., Perez, I.G., Posma, J.M., Haid, M., Sharma, S., Thomas, E.L., Koivula, R.W., Bizzotto, R., Mari, A., Giordano, G.N., Pavo, I., Schwenk, J., De Masi, F., Tsirigos, K., Brunak, S., Vinuela, A., Mahajan, A., McDonald, T.J., Kokkola, T., Teare, H.J.A., Hansen, T.H., Fernandez, J., Jones, A., Jennison, C., Walker, M., McCarthy, M., Pedersen, O., Reutten, H., Forgie, I., Bell, J.D., Pearson, E., Franks, P.W., Adamski, J., Holmes, E. and Frost, G.S. 2020. Dietary metabolite profiling brings new insight into the relationship between nutrition and metabolic risk: An IMI Direct study. EBioMedicine. 58 102932. https://doi.org/10.1016/j.ebiom.2020.102932

Ethnic Differences in Body Fat Deposition and Liver Fat Content in Two UK-Based Cohorts
Alenaini, Wareed, Parkinson, J., McCarthy, John P., Goldstone, Anthony P., Wilman, Henry R., Banerjee, Rajarshi, Yaghootkar, Hanieh, Bell, Jimmy D. and Thomas, E.L. 2020. Ethnic Differences in Body Fat Deposition and Liver Fat Content in Two UK-Based Cohorts. Obesity (Silver Spring, Md.). 28 (11), pp. 2142-2152. https://doi.org/10.1002/oby.22948

Machine Learning Prediction of Susceptibility to Visceral Fat Associated Diseases
Aldraimli, M., Soria, D., Parkinson, J., Thomas, E.L., Bell, J.D., Dwek, M. and Chaussalet, T.J. 2020. Machine Learning Prediction of Susceptibility to Visceral Fat Associated Diseases. Health and Technology. 10, pp. 925-944. https://doi.org/10.1007/s12553-020-00446-1

The UK Biobank imaging enhancement of 100,000 participants: rationale, data collection, management and future directions
Littlejohns, T., Holliday, J., Gibson, L., Garratt, S., Oesingmann, N., Alfaro-Almagro, F., Bell, J.D., Boultwood, C., Collins, R., Conroy, M., Crabtree, N., Doherty, N., Frangi, A., Harvey, N., Leeson, P., Miller, K., Neubauer, S., Petersen, S., Sellors, J., Sheard, S., Smith, S., Sudlow, C., Matthews, P. and Allen, N. 2020. The UK Biobank imaging enhancement of 100,000 participants: rationale, data collection, management and future directions. Nature Communications . 11 2624. https://doi.org/10.1038/s41467-020-15948-9

HDL-apoA-I kinetics in response to 16 weeks exercise training in men with non-alcoholic fatty liver disease (NAFLD)
Whyte, M.B, Shojaee-Moradie, F., Sharaf, S.E., Cuthbertson, D.J., Kemp, G.J., Barrett, M., Jackson, N.C., Herring, R.A, Wright, J., Thomas, E.L., Bell, J.D. and Umpleby, A.M. 2020. HDL-apoA-I kinetics in response to 16 weeks exercise training in men with non-alcoholic fatty liver disease (NAFLD). American Journal of Physiology - Endocrinology and Metabolism. 318 (6), pp. E839-E847. https://doi.org/10.1152/ajpendo.00019.2020

Snacking on whole almonds for 6 weeks improves endothelial function and lowers LDL cholesterol but does not affect liver fat and other cardiometabolic risk factors in healthy adults: the ATTIS study, a randomized controlled trial
Dikariyanto, V., Smith, L., Francis, L., Robertson, M., Kusaslan, E., O’Callaghan-Latham, M., Palanche, C., D’Annibale, M., Christodoulou, D., Basty, N., Whitcher, B., Shuaib, H., Charles-Edwards, G., Chowienczyk, P.J., Ellis, P. R., Berry, S.E. and Hall, W. 2020. Snacking on whole almonds for 6 weeks improves endothelial function and lowers LDL cholesterol but does not affect liver fat and other cardiometabolic risk factors in healthy adults: the ATTIS study, a randomized controlled trial. American Journal of Clinical Nutrition. 111 (6), p. 1178–1189. https://doi.org/10.1093/ajcn/nqaa100

Ethnic differences in adiposity and diabetes risk – insights from genetic studies
Yaghootkar, H., Bell, J.D., Whitcher, B. and Thomas, E.L. 2020. Ethnic differences in adiposity and diabetes risk – insights from genetic studies. Journal of Internal Medicine. 288 (3), pp. 271-283. https://doi.org/10.1111/joim.13082

Automated Measurement of Pancreatic Fat and Iron Concentration Using Multi-Echo and T1-Weghted MRI Data
Basty, N., Liu, Y., Cule, M., Thomas, E.L., Bell, J.D. and Whitcher, B. 2020. Automated Measurement of Pancreatic Fat and Iron Concentration Using Multi-Echo and T1-Weghted MRI Data. International Symposium on Biomedical Imaging 2020. Iowa City, USA 03 - 07 Apr 2020 IEEE . https://doi.org/10.1109/ISBI45749.2020.9098650

Genome-wide and Mendelian randomisation studies of liver MRI yield insights into the pathogenesis of steatohepatitis
Parisinos, C.A., Wilman, H., Thomas, E.L., Kelly, M., Nicholls, R.C., McGonigle, J., Neubauer, S., Hingorani, A.D., Patel, R.S., Hemingway, H., Bell, J.D., Banerjee, R and Yaghootkar, H. 2020. Genome-wide and Mendelian randomisation studies of liver MRI yield insights into the pathogenesis of steatohepatitis. Journal of Hepatology. 73, pp. 241-51. https://doi.org/10.1016/j.jhep.2020.03.032

The role of physical activity in metabolic homeostasis before and after the onset of type 2 diabetes: an IMI DIRECT study
Koivula, R.W., Atabaki-Pasdar, N, Giordano, G.N., White, T., Adamski, J., Bell, J.D., Beulens, J, Brage, S, Brunak, S., De Masi, F., Dermitzakis, E.T., Forgie, I.M., Frost, G.S., Hansen, T., Hansen, T.H., Hattersley, A., Kokkola, T., Kurbasic, A., Laakso, M., Mari, A., McDonald T.J., Pedersen, O., Rutters, F., Schwenk, J.M, Teare, H.J.A., Thomas, E.L., Vinuela, A., Mahajan, A., McCarthy, M.I., Ruetten, H., Walker, M., Pearson, E., Pavo, I. and Franks, P.W. 2020. The role of physical activity in metabolic homeostasis before and after the onset of type 2 diabetes: an IMI DIRECT study. Diabetologia. https://doi.org/10.1007/s00125-019-05083-6

A network analysis to identify mediators of germline-driven differences in breast cancer prognosis
Maria Escala-Garcia, Jean Abraham, Irene L. Andrulis, Hoda Anton-Culver, Volker Arndt, Alan Ashworth, Paul L. Auer, Päivi Auvinen, Matthias W. Beckmann, Jonathan Beesley, Sabine Behrens, Javier Benitez, Marina Bermisheva, Carl Blomqvist, William Blot, Natalia V. Bogdanova, Stig E. Bojesen, Manjeet K. Bolla, Anne-Lise Børresen-Dale, Hiltrud Brauch, Hermann Brenner, Sara Y. Brucker, Barbara Burwinkel, Carlos Caldas, Federico Canzian, Jenny Chang-Claude, Stephen J. Chanock, Suet-Feung Chin, Christine L. Clarke, Fergus J. Couch, Angela Cox, Simon S. Cross, Kamila Czene, Mary B. Daly, Joe Dennis, Peter Devilee, Janet A. Dunn, Alison M. Dunning, Miriam Dwek, Helena M. Earl, Diana M. Eccles, A. Heather Eliassen, Carolina Ellberg, D. Gareth Evans, Peter A. Fasching, Jonine Figueroa, Henrik Flyger, Manuela Gago-Dominguez, Susan M. Gapstur, Montserrat García-Closas, José A. García-Sáenz, Mia M. Gaudet, Angela George, Graham G. Giles, David E. Goldgar, Anna González-Neira, Mervi Grip, Pascal Guénel, Qi Guo, Christopher A. Haiman, Niclas Håkansson, Ute Hamann, Patricia A. Harrington, Louise Hiller, Maartje J. Hooning, John L. Hopper, Anthony Howell, Chiun-Sheng Huang, Guanmengqian Huang, David J. Hunter, Anna Jakubowska, Esther M. John, Rudolf Kaaks, Pooja Middha Kapoor, Renske Keeman, Cari M. Kitahara, Linetta B. Koppert, Peter Kraft, Vessela N. Kristensen, Diether Lambrechts, Loic Le Marchand, Flavio Lejbkowicz, Annika Lindblom, Jan Lubiński, Arto Mannermaa, Mehdi Manoochehri, Siranoush Manoukian, Sara Margolin, Maria Elena Martinez, Tabea Maurer, Dimitrios Mavroudis, Alfons Meindl, Roger L. Milne, Anna Marie Mulligan, Susan L. Neuhausen, Heli Nevanlinna, William G. Newman, Andrew F. Olshan, Janet E. Olson, Håkan Olsson, Nick Orr, Paolo Peterlongo, Christos Petridis, Ross L. Prentice, Nadege Presneau, Kevin Punie, Dhanya Ramachandran, Gad Rennert, Atocha Romero, Mythily Sachchithananthan, Emmanouil Saloustros, Elinor J. Sawyer, Rita K. Schmutzler, Lukas Schwentner, Christopher Scott, Jacques Simard, Christof Sohn, Melissa C. Southey, Anthony J. Swerdlow, Rulla M. Tamimi, William J. Tapper, Manuel R. Teixeira, Mary Beth Terry, Heather Thorne, Rob A. E. M. Tollenaar, Ian Tomlinson, Melissa A. Troester, Thérèse Truong, Clare Turnbull, Celine M. Vachon, Lizet E. van der Kolk, Qin Wang, Robert Winqvist, Alicja Wolk, Xiaohong R. Yang, Argyrios Ziogas, Paul D. P. Pharoah, Per Hall, Lodewyk F. A. Wessels, Georgia Chenevix-Trench, Gary D. Bader, Thilo Dörk, Douglas F. Easton, Sander Canisius & Marjanka K. Schmidt, Dwek, M. and Presneau, Nadège 2020. A network analysis to identify mediators of germline-driven differences in breast cancer prognosis. Nature Communications . 16 (11) 312. https://doi.org/10.1038/s41467-019-14100-6

Berberine for prevention of dementia associated with diabetes and its comorbidities: A systematic review
Shinjyo, N., Parkinson, J., Bell, J.D., Katsuno, T. and Bligh, S.W.A. 2020. Berberine for prevention of dementia associated with diabetes and its comorbidities: A systematic review. Journal of Integrative Medicine. 18 (2), pp. 125-151. https://doi.org/10.1016/j.joim.2020.01.004

Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes.
Fachal, L., Aschard, H., Beesley, J., Barnes, D.R., Allen, J., Kar, S., Pooley, K.A., Dennis, J., Michailidou, K., Turman, C., Soucy, P., Lemaçon, A., Lush, M., Tyrer, J.P., Dunning, A.M. and Dwek, M. 2020. Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes. Nature Genetics. 52, pp. 56-73. https://doi.org/10.1038/s41588-019-0537-1

Serum IgA1 shows increased levels of α 2,6-linked sialic acid in breast cancer
Lomax-Browne, Hannah J., Robertson, Claire, Antonopoulos, Aristotelis, Leathem, Anthony J. C., Haslam, Stuart M., Dell, Anne and Dwek, M. 2019. Serum IgA1 shows increased levels of α 2,6-linked sialic acid in breast cancer. Interface Focus. 9 (2), p. 20180079 20180079. https://doi.org/10.1098/rsfs.2018.0079

Genome-wide association study of germline variants and breast cancer-specific mortality.
Escala-Garcia, M., Guo, Q., Dörk, T., Canisius, S., Keeman, R., Dennis, J., Beesley, J., Lecarpentier, J., Bolla, M.K., Wang, Q., Abraham, J., Andrulis, I.L., Anton-Culver, H., Schmidt, M.K. and Dwek, M. 2019. Genome-wide association study of germline variants and breast cancer-specific mortality. British Journal of Cancer. 120, pp. 647-657. https://doi.org/10.1038/s41416-019-0393-x

New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders
Evangelou, E., Gao, H., Chu, C., Ntritsos, G., Blakeley, P., Butts, A., Pazoki, R., Suzuki, H., Koskeridis, F., Yiorkas, A., Karaman, I., Elliott, J., Luo, Q., Aeschbacher, S., Bartz, T., Baumeister, S., Braund, P., Brown, M., Brody, J., Clarke, T., Dimou, N., Faul, J., Homuth, G., Jackson, A., Kentistou, K., Joshi, P., Lemaitre, R., Lind, P., Lyytikäinen, L., Mangino, M., Milaneschi, Y., Nelson, C., Nolte, I., Perälä, M., Polasek, O., Porteous, D., Ratliff, S., Smith, J., Stančáková, A., Teumer, A., Tuominen, S., Thériault, S., Vangipurapu, J., Whitfield, J., Wood, A., Yao, J., Yu, B., Zhao, W., Arking, D., Auvinen, J., Liu, C., Männikkö, M., Risch, L., Rotter, J., Snieder, H., Veijola, J., Blakemore, A., Boehnke, M., Campbell, H., Conen, D., Eriksson, J., Grabe, H., Guo, X., van der Harst, P., Hartman, C., Hayward, C., Heath, A., Jarvelin, M., Kähönen, M., Kardia, S., Kühne, M., Kuusisto, J., Laakso, M., Lahti, J., Lehtimäki, T., McIntosh, A., Mohlke, K., Morrison, A., Martin, N., Oldehinkel, A., Penninx, B., Psaty, B., Raitakari, O., Rudan, I., Samani, N., Scott, L., Spector, T., Verweij, N., Weir, D., Wilson, J., Levy, D., Tzoulaki, I., Bell, J.D., Matthews, P., Rothenfluh, A., Desrivières, S., Schumann, G. and Elliott, P. 2019. New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders. Nature Human Behaviour. 3 (9), pp. 950-961. https://doi.org/10.1038/S41562-019-0653-Z

Neuroconductor: an R platform for medical imaging analysis
Muschelli, J., Gherman, A., Fortin, J.P., Avants, B., Whitcher, B., Clayden, J.D., Caffo, B.S. and Crainiceanu, C.M. 2019. Neuroconductor: an R platform for medical imaging analysis. Biostatistics. 20 (2), pp. 218-239. https://doi.org/10.1093/biostatistics/kxx068

A Framework for Automatic Morphological Feature Extraction and Analysis of Abdominal Organs in MRI Volumes
Asaturyan, H., Thomas, E.L., Bell, J.D. and Villarini, B. 2019. A Framework for Automatic Morphological Feature Extraction and Analysis of Abdominal Organs in MRI Volumes. Journal of Medical Systems. 43 334. https://doi.org/10.1007/s10916-019-1474-3

Advancing Pancreas Segmentation in Multi-protocol MRI Volumes using Hausdorff-Sine Loss Function
Asaturyan, H., Thomas, E.L., Fitzpatrick, J., Bell, J.D. and Villarini, B. 2019. Advancing Pancreas Segmentation in Multi-protocol MRI Volumes using Hausdorff-Sine Loss Function. 10th International Workshop on Machine Learning in Medical Imaging (MLMI 2019) in conjunction with MICCAI 2019. Shenzen, China 13 Oct 2019 Springer. https://doi.org/10.1007/978-3-030-32692-0_4

The pineal hormone melatonin inhibits doxorubicin-induced mitochondrial dysfunction and apoptosis in cardiomyocytes
Kasi Ganeshan, T., Bell, J.D. and Chong, Nelson W. 2019. The pineal hormone melatonin inhibits doxorubicin-induced mitochondrial dysfunction and apoptosis in cardiomyocytes. ESC Congress 2019. Paris, France 31 Aug - 04 Sep 2019

The pineal hormone melatonin inhibits doxorubicin-induced mitochondrial dysfunction and apoptosis in cardiomyocytes
Kasi Ganeshan, T., Bell, J.D. and Chong, Nelson W. 2019. The pineal hormone melatonin inhibits doxorubicin-induced mitochondrial dysfunction and apoptosis in cardiomyocytes. Heart Failure 2019 and the World Congress on Acute Heart Failure. Megaron Athens International Conference Centre, Greece 25 - 28 May 2019 https://doi.org/10.1002/ejhf.1488

Cannabidiol is a Novel Modulator of Bacterial Membrane Vesicles
Kosgodage, U., Matewele, P., Awamaria, B., Kraev, I., Warde, P., Mastroianni, G., Nunn, A., Guy, G.W., Bell, J.D., Inal, J.M. and Lange, S. 2019. Cannabidiol is a Novel Modulator of Bacterial Membrane Vesicles. Frontiers in Cellular and Infection Microbiology. 9 324. https://doi.org/10.3389/fcimb.2019.00324

Controlling Understaffing with Conditional Value-at-Risk Constraint for an Integrated Nurse Scheduling Problem under Patient Demand Uncertainty
He, F., Chaussalet, T.J. and Qu, R. 2019. Controlling Understaffing with Conditional Value-at-Risk Constraint for an Integrated Nurse Scheduling Problem under Patient Demand Uncertainty. Operations Research Perspectives. 6 (2019), p. 100119 100119. https://doi.org/10.1016/j.orp.2019.100119

Genetic studies of abdominal MRI data identify genes regulating hepcidin as major determinants of liver iron concentration
Wilman, H.R., Parisinos, C.A., Atabaki-Pasdar, N., Kelly, M., Thomas, E.L., Neubauer, S., Mahajan, A., Hingorani, A.D., Patel, R.S., Hemingway, H., Franks, P.W., Bell, J.D., Banerjee, R. and Yaghootkar, H. 2019. Genetic studies of abdominal MRI data identify genes regulating hepcidin as major determinants of liver iron concentration. Journal of Hepatology. 71 (3), pp. 594-602. https://doi.org/10.1016/j.jhep.2019.05.032

LEAP2 changes with body mass and food intake in humans and mice
Mani, B.K., Puzziferri, N., He, Z., Rodriguez, J.A., Osborne-Lawrence, S., Metzger, N.P., Chhina, N., Gaylinn, B.D., Thorner, M.O., Thomas, E.L., Bell, J.D., Williams, K.W., Goldstone, A.P. and Zigman, J.M. 2019. LEAP2 changes with body mass and food intake in humans and mice. Journal of Clinical Investigation. 129 (9), pp. 3909-3923. https://doi.org/10.1172/JCI125332

Modelling the Home Health Care Nurse Scheduling Problem for Patients with Long-Term Conditions in the UK
He, F., Chaussalet, T.J. and Qu, R. 2019. Modelling the Home Health Care Nurse Scheduling Problem for Patients with Long-Term Conditions in the UK. 33rd International ECMS Conference on modelling and Simulation. Universita degli Studi della Campania, Caserta, Area of Napoli, Italy 11 - 14 Jun 2019 European Council for Modeling and Simulation. https://doi.org/10.7148/2019-0317

Design and implementation of a deep recurrent model for prediction of readmission in urgent care using electronic health records
Zebin, T. and Chaussalet, T.J. 2019. Design and implementation of a deep recurrent model for prediction of readmission in urgent care using electronic health records. 16th IEEE International Conference on Computational Intelligence in Bioinformatics and Computational Biology. Certosa di Pontignano, Siena - Tuscany, Italy 09 - 11 Jul 2019 IEEE . https://doi.org/10.1109/CIBCB.2019.8791466

A deep learning approach for length of stay prediction in clinical settings from medical records
Zebin, T., Rezvy, S. and Chaussalet, T.J. 2019. A deep learning approach for length of stay prediction in clinical settings from medical records. 16th IEEE International Conference on Computational Intelligence in Bioinformatics and Computational Biology. Certosa di Pontignano, Siena - Tuscany, Italy 09 - 11 Jul 2019 IEEE . https://doi.org/10.1109/CIBCB.2019.8791477

Combining Clustering and Classification Ensembles: A Novel Pipeline to Identify Breast Cancer Profiles
Agrawal, U., Soria, D., Wagner, C., Garibaldi, J.M., Ellis, I.O., Bartlett, J.M.S., Cameron, D., Rakha, E.A. and Green, A.R. 2019. Combining Clustering and Classification Ensembles: A Novel Pipeline to Identify Breast Cancer Profiles. Artificial Intelligence in Medicine. 97, pp. 27-37. https://doi.org/10.1016/j.artmed.2019.05.002

Ethnic differences in intrahepatic lipid and its association with hepatic insulin sensitivity and insulin clearance between men of Black and White ethnicity with early type 2 diabetes
Hakim, O., Bello, O., Bonadonna, O.C., Mohandas, C., Shojaee-Moradie, F., Jackson, N., Boselli, L., Whitcher, B., Shuaib, H., Alberti, K.G.M.M., Peacock, J.L., Umpleby, A.M., Charles-Edwards, E., Amiel, S.A. and Goff, L.M. 2019. Ethnic differences in intrahepatic lipid and its association with hepatic insulin sensitivity and insulin clearance between men of Black and White ethnicity with early type 2 diabetes. Diabetes, Obesity and Metabolism. 21 (9), pp. 2163-2168. https://doi.org/10.1111/dom.13771

Sub‐phenotyping Metabolic Disorders Using Body Composition: An Individualized, Nonparametric Approach Utilizing Large Data Sets
Linge, J., Whitcher, B., Borga, M. and Dahlqvist Leinhard, O. 2019. Sub‐phenotyping Metabolic Disorders Using Body Composition: An Individualized, Nonparametric Approach Utilizing Large Data Sets. Obesity. 27 (7), pp. 1190-1199. https://doi.org/10.1002/oby.22510

Fuzzy Integral Driven Ensemble Classification using A Priori Fuzzy Measures
Agrawal, U., Wagner, C., Garibaldi, J.M. and Soria, D. 2019. Fuzzy Integral Driven Ensemble Classification using A Priori Fuzzy Measures. International Conference on Fuzzy Systems (FUZZ-IEEE 2019). 23 - 26 Jun 2019 IEEE . https://doi.org/10.1109/FUZZ-IEEE.2019.8858821

Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: descriptive characteristics of the epidemiological studies within the IMI DIRECT Consortium
Koivula, R.W., Forgie, I.M., Kurbasic, A., Viñuela, A., Heggie, A., Giordano, G.N., Hansen, T.H., Hudson, M., Koopman, A.D., Rutters, F., Siloaho, M., Allin, K.H., Brage, S., Brorsson, C.A., Dawed, A.Y., De Masi, F., Groves, C.J., Kokkola, T., Mahajan, A., Perry, M.H., Rauh, S.P., Ridderstråle, M., Teare, H.J.A., Thomas, E.L., Tura, A., Vestergaard, H., White, T., Adamski, J., Bell, J.D., Beulens, J., Brunak, S., Dermitzakis, E.T., Froguel, P., Frost, G., Gupta, R., Hansen, T., Hattersley, A., Jablonka, B., Kaye, J., Laakso, M., McDonald, T.J., Pedersen, O., Schwenk, J.M., Pavo, I., Mari, A., McCarthy, M.I., Ruetten, H., Walker, M., Pearson, E. and Franks, P.W. 2019. Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: descriptive characteristics of the epidemiological studies within the IMI DIRECT Consortium. Diabetologia. 62 (9), pp. 1601-1615. https://doi.org/10.1007/s00125-019-4906-1

Intraperitoneal delivery of acetate-encapsulated liposomal nanoparticles for neuroprotection of the penumbra in a rat model of ischemic stroke
So, P.W., Ekonomou, A., Galley, K., Brody, Leigh, Sahuri-Arisoylu, M., Rattray, I., Cash, D. and Bell, J.D. 2019. Intraperitoneal delivery of acetate-encapsulated liposomal nanoparticles for neuroprotection of the penumbra in a rat model of ischemic stroke. International Journal of Nanomedicine. 2019 (14), p. 1979–1991. https://doi.org/10.2147/IJN.S193965

Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer.
Ferreira, M.A., Gamazon, E.R., Al-Ejeh, F., Aittomäki, K., Andrulis, I.L., Anton-Culver, H., Arason, A., Arndt, V., Aronson, K.J., Arun, B.K., Asseryanis, E., Azzollini, J., Chenevix-Trench, G., Dwek, M. and Presneau, Nadège 2019. Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer. Nature Communications . 10, p. 1741. https://doi.org/10.1038/s41467-018-08053-5

Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes.
Mavaddat, N., Michailidou, K., Dennis, J., Lush, M., Fachal, L., Lee, A., Tyrer, J.P., Chen, T.H., Wang, Q., Bolla, M.K., Yang, X., Adank, M.A., Ahearn, T., Aittomäki, K., Allen, J., Easton, D.F., Dwek, M. and Presneau, Nadège 2019. Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes. American Journal of Human Genetics. 104 (1), pp. 21-34. https://doi.org/10.1016/j.ajhg.2018.11.002

Temporal Comorbidity-Adjusted Risk of Emergency Readmission (T-CARER): A Tool for Comorbidity Risk Assessment
Mesgarpour, M., Chaussalet, T.J. and Chahed, S. 2019. Temporal Comorbidity-Adjusted Risk of Emergency Readmission (T-CARER): A Tool for Comorbidity Risk Assessment. Applied Soft Computing. 79, pp. 163-185. https://doi.org/10.1016/j.asoc.2019.03.015

The combined expression of solute carriers is associated with a poor prognosis in highly proliferative ER+ breast cancer
El Ansari, R., Craze, M.L., Alfarsi, L., Soria, D., Diez-Rodriguez, M., Nolan, C.C., Ellis, I.O., Rakha, E.A. and Green, A.R. 2019. The combined expression of solute carriers is associated with a poor prognosis in highly proliferative ER+ breast cancer. Breast Cancer Research and Treatment. 175 (1), pp. 27-38. https://doi.org/10.1007/s10549-018-05111-w

Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer
Dwek, M. 2019. Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer. Nature Communications . 10 1741. https://doi.org/10.1038/s41467-018-08053-5

Cannabidiol Affects Extracellular Vesicle Release, miR21 and miR126, and Reduces Prohibitin Protein in Glioblastoma Multiforme Cells
Kosgodage, U., Uysal Onganer, P., Maclatchy, A., Mould, R., Nunn, A.V.W., Guy, G.W., Kraev, I., Chatterton, N.P., Thomas, E.L., Inal, J.M., Bell, J.D. and Lange, S. 2019. Cannabidiol Affects Extracellular Vesicle Release, miR21 and miR126, and Reduces Prohibitin Protein in Glioblastoma Multiforme Cells. Translational Oncology. 12 (3), pp. 513-522. https://doi.org/10.1016/j.tranon.2018.12.004

Shared heritability and functional enrichment across six solid cancers.
Jiang, X., Finucane, H.K., Schumacher, F.R., Schmit, S.L., Tyrer, J.P., Han, Y., Michailidou, K., Lesseur, C., Kuchenbaecker, K.B., Dennis, J., Conti, D.V., Casey, G., Gaudet, M.M., Lindström, S. and Dwek, M. 2019. Shared heritability and functional enrichment across six solid cancers. Nature Communications . 10 431. https://doi.org/10.1038/s41467-018-08054-4

Identifying Heavy Goods Vehicle Driving Styles in the United Kingdom
Figueredo, G.P., Agrawal, U., Mase, J.M.M., Mesgarpour, M., Wagner, C., Soria, D., Garibaldi, J.M., Siebers, P.O. and John, R.I. 2019. Identifying Heavy Goods Vehicle Driving Styles in the United Kingdom. IEEE Transactions on Intelligent Transportation Systems. 20 (9), pp. 3324-3336. https://doi.org/10.1109/TITS.2018.2875343

Genome-wide and abdominal MRI-imaging data provides evidence that a genetically determined favourable adiposity phenotype is characterized by lower ectopic liver fat and lower risk of type 2 diabetes, heart disease and hypertension
Ji, Y., Yiorkas, A.M., Frau, F., Mook-Kanamori, D., Staiger, H., Thomas, E.L., Atabaki-Pasdar, N., Campbell, A., Tyrrell, J., Jones, S.E., Beaumont, R.N., Wood, A.R., Tuke, M.A., Ruth, K.S., Mahajan, A., Murray, A., Freathy, R.M., Weedon, M.N., Hattersley, A.T., Hayward, C., Machann, J., Häring, H.U., Franks, P.W., de Mutsert, R., Pearson, E., Stefan, N., Frayling, T.M., Allebrandt, K.V., Bell, J.D., Blakemore, A.I. and Yaghootkar, H. 2019. Genome-wide and abdominal MRI-imaging data provides evidence that a genetically determined favourable adiposity phenotype is characterized by lower ectopic liver fat and lower risk of type 2 diabetes, heart disease and hypertension. Diabetes. 68 (1), pp. 207-219. https://doi.org/10.2337/db18-0708

Associations of obesity and circulating insulin and glucose with breast cancer risk: a Mendelian randomization analysis
Xiang Shu, Lang Wu, Nikhil K Khankari, Xiao-Ou Shu, Thomas J Wang, Kyriaki Michailidou, Manjeet K Bolla, Qin Wang, Joe Dennis, Roger L Milne, Marjanka K Schmidt, Paul D P Pharoah, Irene L Andrulis, David J Hunter, Jacques Simard, Douglas F Easton, Wei Zheng, Breast Cancer Association Consortium and Dwek, M. 2019. Associations of obesity and circulating insulin and glucose with breast cancer risk: a Mendelian randomization analysis . International Journal of Epidemiology. 48 (3), pp. 795-806. https://doi.org/10.1093/ije/dyy201

An End-to-End Deep Learning Histochemical Scoring System for Breast Cancer TMA
Liu, J., Xu, B., Zheng, C., Gong, Y., Garibaldi, J.M., Soria, D., Green, A., Ellis, I.O., Zou, W. and Qiu, G. 2019. An End-to-End Deep Learning Histochemical Scoring System for Breast Cancer TMA. IEEE Transactions on Medical Imaging. 38 (2), pp. 617-628. https://doi.org/10.1109/TMI.2018.2868333

The effects of dietary supplementation with inulin and inulin-propionate ester on hepatic steatosis in adults with non-alcoholic fatty liver disease
Chambers, E.S., Byrne, C.S., Rugyendo, A., Morrison, D.J., Preston, T., Tedford, M.C., Bell, J.D., Thomas, E.L., Akbar, A.N., Riddell, N.E., Sharma, R., Thursz, M.R., Manousou, P. and Frost, G. 2019. The effects of dietary supplementation with inulin and inulin-propionate ester on hepatic steatosis in adults with non-alcoholic fatty liver disease. Diabetes, Obesity and Metabolism. 21 (2), pp. 372-376. https://doi.org/10.1111/dom.13500

Reference range of liver corrected T1 values in a population at low risk for fatty liver disease-a UK Biobank sub-study, with an appendix of interesting cases
Mojtahed, A., Kelly, C.J., Herlihy, A.H., Kin, S., Wilman, H.R., McKay, A., Kelly, M., Milanesi, M., Neubauer, S,, Thomas, E.L., Bell, J.D., Banerjee, R. and Harisinghani, M. 2019. Reference range of liver corrected T1 values in a population at low risk for fatty liver disease-a UK Biobank sub-study, with an appendix of interesting cases. Abdominal Radiology. 44 (1), pp. 72-84. https://doi.org/10.1007/s00261-018-1701-2

Prostate cancer detection using quantitative T2 and T2-weighted imaging: The effects of 5-alpha-reductase inhibitors in men on active surveillance
Giganti, F., Gambarota, G., Moore, C.M., Robertson, N.L., Mccartan, N., Jameson, C., Bott, S.R., Winkler, M., Whitcher, B., Castro-Santamaria, R., Emberton, M., Allen, C. and Kirkham, A. 2018. Prostate cancer detection using quantitative T2 and T2-weighted imaging: The effects of 5-alpha-reductase inhibitors in men on active surveillance. Journal of Magnetic Resonance Imaging. 47 (6), pp. 1646-1653. https://doi.org/10.1002/jmri.25891

Transformation of UML Activity Diagram for Enhanced Reasoning
Chishti, I., Basukoski, A., Chaussalet, T.J. and Beeknoo, N. 2018. Transformation of UML Activity Diagram for Enhanced Reasoning. Future Technologies Conference 2018. Vancouver, Canada 13 - 14 Nov 2018 Springer. https://doi.org/10.1007/978-3-030-02683-7_33

Measurement of liver iron by magnetic resonance imaging in the UK Biobank population
McKay, A., Wilman, H., Dennis, A., Kelly, M., Gyngell, M.L., Neubauer, S., Bell, J.D., Banerjee, R. and Thomas, E.L. 2018. Measurement of liver iron by magnetic resonance imaging in the UK Biobank population. PLoS ONE. 13 (12) e0209340. https://doi.org/10.1371/journal.pone.0209340

Interpretability and Complexity of Design in the Creation of Fuzzy Logic Systems - A User Study
Razak, T.R., Garibaldi, J.M., Wagner, C., Pourabdollah, A. and Soria, D. 2018. Interpretability and Complexity of Design in the Creation of Fuzzy Logic Systems - A User Study. 2018 IEEE Symposium Series on Computational Intelligence. Bengaluru, India 18 - 21 Nov 2018 IEEE . https://doi.org/10.1109/SSCI.2018.8628924

Non-alcoholic fatty liver disease: relationship with cardiovascular risk markers and clinical endpoints
Buckley, A., Thomas, E.L., Lessan, N., Trovato, F.M., Trovato, G.M. and Taylor-Robinson, S.D. 2018. Non-alcoholic fatty liver disease: relationship with cardiovascular risk markers and clinical endpoints. Diabetes Research and Clinical Practice. 144, pp. 144-152. https://doi.org/10.1016/j.diabres.2018.08.011

Cannabidiol (CBD) is a Novel Inhibitor for Exosome and Microvesicle (EMV) Release in Cancer
Kosgodage, U., Mould, R., Henley, A., Nunn, A.V.W., Guy, G.W., Thomas, E.L., Inal, J.M., Bell, J.D. and Lange, S. 2018. Cannabidiol (CBD) is a Novel Inhibitor for Exosome and Microvesicle (EMV) Release in Cancer. Frontiers in Pharmacology. 9 889. https://doi.org/10.3389/fphar.2018.00889

Discovering Business Processes in CRM Systems by leveraging unstructured text data
Banziger, R.B., Basukoski, A. and Chaussalet, T.J. 2018. Discovering Business Processes in CRM Systems by leveraging unstructured text data. The 4th IEEE International Conference on Data Science and Systems (DSS-2018). Exeter, UK 28 - 30 Jun 2018 IEEE . https://doi.org/10.1109/HPCC/SmartCity/DSS.2018.00257

A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer.
Wu, L., Shi, W., Long, J., Guo, X., Michailidou, K., Beesley, J., Bolla, M.K., Shu, X.O., Lu, Y., Cai, Q., Al-Ejeh, F., Rozali, E., Wang, Q., Dennis, J., Li, B., Zeng, C., Feng, H., Zheng, W. and Dwek, M. 2018. A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer. Nature Genetics. 50, pp. 968-978. https://doi.org/10.1038/s41588-018-0132-x

Glycosylation and Disease
Dwek, M. and Markiv, A. 2018. Glycosylation and Disease. eLS. 10.1002/9780470015902.a0002151.pub3. https://doi.org/10.1002/9780470015902.a0002151.pub3

Comparison of Fuzzy Integral-Fuzzy Measure based Ensemble Algorithms with the State-of-the-art Ensemble Algorithms
Agrawal, U., Pinar, A.J., Wagner, C., Havens, T.C., Soria, D. and Garibaldi, J.M. 2018. Comparison of Fuzzy Integral-Fuzzy Measure based Ensemble Algorithms with the State-of-the-art Ensemble Algorithms. Medina, J., Ojeda-Aciego, M., Verdegay, J.L., Perfilieva, I., Bouchon-Meunier, B. and Yager, R.R. (ed.) 17th International Conference on Information Processing and Management of Uncertainty in Knowledge-Based Systems. Cadiz, Spain 11 - 15 Jun 2018 Springer. https://doi.org/10.1007/978-3-319-91479-4

Plasma metabolome analysis identifies distinct human metabotypes in the postprandial state with different susceptibility to weight loss–mediated metabolic improvements
Fiamoncini, J., Rundle, M., Gibbons, H., Thomas, E.L., Geillinger-Kästle, K., Bunzel, D., Trezzi, J.P., Kiselova-Kaneva, J., Wopereis, S., Wahrheit, J., Kulling, S.E., Hiller, K., Sonntag, D., Ivanova, D., van Ommen, B, Frost, G., Brennan, L., Bell, J.D. and Daniel, H. 2018. Plasma metabolome analysis identifies distinct human metabotypes in the postprandial state with different susceptibility to weight loss–mediated metabolic improvements. FASEB Journal. 32 (10), p. 5447–5458. https://doi.org/10.1096/fj.201800330R

Body Composition Profiling in the UK Biobank Imaging Study
Linge, J., Borger Magnus, West, J., Tuthill, T., Miller, M.R., Dumitriu, A., Thomas, E.L., Romu, T., Tunón, P., Bell, J.D. and Leinhard, O.D. 2018. Body Composition Profiling in the UK Biobank Imaging Study. Obesity. 26 (11), pp. 1785-1795. https://doi.org/10.1002/oby.22210

Advanced body composition assessment: from body mass index to body composition profiling
Borga, M., West, J., Bell, J.D., Harvey, N.C., Romu, T., Heymsfield, S.B. and Leinhard, O.D. 2018. Advanced body composition assessment: from body mass index to body composition profiling. Journal of Investigative Medicine. 66 (5), pp. 887-895. https://doi.org/10.1136/jim-2018-000722

Modeling Patient Flows: A Temporal Logic Approach
Chishti, I., Basukoski, A. and Chaussalet, T.J. 2018. Modeling Patient Flows: A Temporal Logic Approach. Journal On Computing. 6 (1) 1516. https://doi.org/10.5176/2251-3043_6.1.107

Development of a pre-operative scoring system for predicting risk of post-operative paediatric cerebellar mutism syndrome
Liu, J.-F., Dineen, R.A., Avula, S., Chambers, T., Dutta, M., Jaspan, T., MacArthur, D.C., Howarth, S., Soria, D., Quinlan, P., Harave, S., Ong, C.C., Mallucci, C.L., Kumar, R., Pizer, B. and Walker, D.A. 2018. Development of a pre-operative scoring system for predicting risk of post-operative paediatric cerebellar mutism syndrome. British Journal of Neurosurgery. 32 (1), pp. 18-27. https://doi.org/10.1080/02688697.2018.1431204

A multicentre integration of a computer-led follow-up of prostate cancer is valid and safe
Salem, H., Caddeo, G., McFarlane, J., Patel, K., Cochrane, L., Soria, D., Henley, M. and Lund, J. 2018. A multicentre integration of a computer-led follow-up of prostate cancer is valid and safe. BJU international. 122 (3), pp. 418-426 BJU14157. https://doi.org/10.1111/bju.14157

MYC regulation of Glutamine-Proline regulatory axis is key in Luminal B breast cancer
Craze, M.L., Cheung, H., Jewa, N., Coimbra, N.D.M., Soria, D., El-Ansari, R., Aleskandarany, M.A., Cheng, K.W., Diez-Rodriguez, M., Nolan, C.C., Ellis, I.O., Rakha, E. and Green, A.R. 2018. MYC regulation of Glutamine-Proline regulatory axis is key in Luminal B breast cancer. British Journal of Cancer. 118 (2), pp. 258-265. https://doi.org/10.1038/bjc.2017.387

Rifaximin in Non-Alcoholic Steatohepatitis: An Open-Label Pilot Study
Cobbold, J.F.L., Atkinson, S., Marchesi, J.R., Smith, A., Wai, S.N., Stove, J., Shojaee-Moradie, F., Jackson, N.C., Umpleby, A.M., Fitzpatrick, J., Thomas, E.L., Bell, J.D., Holmes, E., Taylor-Robinson, S.D., Goldin, R.D., Yee, M.S., Anstee, Q.M. and Thursz, M.R. 2018. Rifaximin in Non-Alcoholic Steatohepatitis: An Open-Label Pilot Study. Hepatology Research. 48 (1), pp. 69-77. https://doi.org/10.1111/hepr.12904

MRI findings in men on active surveillance for prostate cancer: does dutasteride make MRI visible lesions less conspicuous? Results from a placebo-controlled, randomised clinical trial
Giganti, F., Moore, C.M., Robertson, N.L., McCartan, N., Jameson, C., Bott, S.R.J., Winkler, M., Gambarota, G., Whitcher, B., Castro, R., Emberton, M., Allen, C. and Kirkham, A. 2017. MRI findings in men on active surveillance for prostate cancer: does dutasteride make MRI visible lesions less conspicuous? Results from a placebo-controlled, randomised clinical trial. European Radiology. 27, pp. 4767-4774. https://doi.org/10.1007/s00330-017-4858-0

Dynamic contrast-enhanced magnetic resonance imaging of regional nodal metastasis in nasopharyngeal carcinoma: Correlation with nodal staging
Huang, B., Kwong, D.L.W., Lai, V., Chan, Q., Whitcher, B. and Khong, P.-L. 2017. Dynamic contrast-enhanced magnetic resonance imaging of regional nodal metastasis in nasopharyngeal carcinoma: Correlation with nodal staging. Contrast Media and Molecular Imaging. 2017 4519653. https://doi.org/10.1155/2017/4519653

The Effect of Dutasteride on Magnetic Resonance Imaging Defined Prostate Cancer: MAPPED—A Randomized, Placebo Controlled, Double-Blind Clinical Trial
Moore, C.M., Robertson, N.L., Jichi, F., Damola, A., Ambler, G., Giganti, F., Ridout, A.J., Bott, S.R.J., Winkler, M., Ahmed, H.U., Arya, M., Mitra, A.V., McCartan, N., Freeman, A., Jameson, C., Castro, R., Gambarota, G., Whitcher, B., Allen, C., Kirkham, A. and Emberton, M. 2017. The Effect of Dutasteride on Magnetic Resonance Imaging Defined Prostate Cancer: MAPPED—A Randomized, Placebo Controlled, Double-Blind Clinical Trial. Journal of Urology. 197 (4), pp. 1006-1013. https://doi.org/10.1016/j.juro.2016.11.090

Fermentable carbohydrate stimulates FFAR2-dependent colonic PYY cell expansion to increase satiety
Brooks, L., Viardot, A., Tsakmaki, A., Stolarczyk, E., Howard, J., Cani, P., Everard, A., Sleeth, M., Psichas, A., Anastasovskaj, J., Bell, J.D., Bell-Anderson, K., Mackay, C., Ghatei, M., Bloom, S., Frost, G. and Bewick, G. 2017. Fermentable carbohydrate stimulates FFAR2-dependent colonic PYY cell expansion to increase satiety. Molecular Metabolism. 6 (1), pp. 48-60. https://doi.org/10.1016/J.MOLMET.2016.10.011

Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.
Milne, R.L., Kuchenbaecker, K.B., Michailidou, K., Beesley, J., Kar, S., Lindström, S., Hui, S., Lemaçon, A., Soucy, P., Dennis, J., Jiang, X., Rostamianfar, A., Finucane, H., Simard, J., Dwek, M. and Presneau, Nadège 2017. Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer. Nature Genetics. 49, pp. 1767-1778. https://doi.org/10.1038/ng.3785

Association analysis identifies 65 new breast cancer risk loci
Michailidou, K., Lindström, S., Dennis, J., Beesley, J., Hui, S., Kar, S., Lemaçon, A., Soucy, P., Glubb, D., Rostamianfar, A., Bolla, M.K., Wang, Q., Tyrer, J., Dicks, E., Easton, D.F., Dwek, M. and Presneau, Nadège 2017. Association analysis identifies 65 new breast cancer risk loci. Nature. 551, pp. 92-94. https://doi.org/10.1038/nature24284

Care Home Quality Scorecard: A scorecard inspired approach to benchmark care home quality
Worrall, P. and Chaussalet, T.J. 2017. Care Home Quality Scorecard: A scorecard inspired approach to benchmark care home quality. Operational Research Applied to Health Services. Bath, UK 24 - 28 Jul 2017

Emergency Readmission for Integrated Care (ERIC) Model: Using an Automated Feature Generation & a Multi-Task Learner
Chaussalet, T.J., Mesgarpour, M., Worrall, P. and Chahed, S. 2017. Emergency Readmission for Integrated Care (ERIC) Model: Using an Automated Feature Generation & a Multi-Task Learner. Operational Research Applied to Health Services 2017. Bath, UK 24 - 28 Jul 2017

Modeling and Optimizing Patient Flows
Chishti, I., Basukoski, A. and Chaussalet, T.J. 2017. Modeling and Optimizing Patient Flows. 8th Annual International Conference on ICT: Big Data, Cloud & Security. Singapore 21 - 22 Aug 2017 Global Science & Technology Forum. https://doi.org/10.5176/2251-2136_ICT-BDCS17.52

Impact of liver fat on the differential partitioning of hepatic triacylglycerol into VLDL subclasses on high and low sugar diets
Umpleby, A.M., Shoajee-Moradie, F., Fielding, F., Li, X., Marino, A., Alsini, N, Isherwood, C, Jackson, N.C., Ahmad, A., Stolinski, M., Lovegrove, J.A., Johnsen, S., Mendis, A., Wright, J., Wilinska, M.E., Hovorka, R., Bell, J.D., Thomas, E.L., Frost, G.S. and Griffin, B.A. 2017. Impact of liver fat on the differential partitioning of hepatic triacylglycerol into VLDL subclasses on high and low sugar diets. Clinical Science. 131 (21), pp. 2561-2573. https://doi.org/10.1042/CS20171208

The Potential of Omega-3 Supplementation to Reduce Muscle-Inflammation after Muscle-Damaging Exercise
Kyriakidou, Y., Kantorovich, R.C., Bell, J.D., Monterisi, S. and Dolci, A. 2017. The Potential of Omega-3 Supplementation to Reduce Muscle-Inflammation after Muscle-Damaging Exercise. ACSM Annual Meeting, World Congress on Exercise is Medicine & World Congress on the Basic Science of Exercise and the Brain. Denver, Colorado 30 May - 03 Jun 2017 American College of Sports Medicine. https://doi.org/10.1249/01.mss.0000518523.15295.1c

PhytoCloud: A gamified Mobile Web Application to modulate diet and physical activity of women with breast cancer
Economou, D., Dwek, M., Elliott, B., Ramezanian Kalahroudi, M. and Azimi, T. 2017. PhytoCloud: A gamified Mobile Web Application to modulate diet and physical activity of women with breast cancer. IEEE 30th International Symposium on Computer-Based Medical Systems. Thessaloniki, Greece 22 Jun - 24 Sep 2017 IEEE . https://doi.org/10.1109/CBMS.2017.164

Cationic lipid-based nanoparticles mediate functional delivery of acetate to tumor cells in vivo leading to significant anticancer effects
Brody, L.P., Sahuri Arisoylu, M., Parkinson, J.R., Parkes, H.G., So, P-W, Hajji, N, Thomas, E.L., Frost, G.S., Miller, A.D. and Bell, J.D. 2017. Cationic lipid-based nanoparticles mediate functional delivery of acetate to tumor cells in vivo leading to significant anticancer effects. International Journal of Nanomedicine. 12, pp. 6677-6685. https://doi.org/10.2147/IJN.S135968

The Hormesis of Thinking: A Deeper Quantum Thermodynamic Perspective?
Nunn, A.V.W., Guy, G.W. and Bell, J.D. 2017. The Hormesis of Thinking: A Deeper Quantum Thermodynamic Perspective? International Journal of Neurorehabilitation. 4 (3), p. 272 272. https://doi.org/10.4172/2376-0281.1000272

Thyroid Hormone Receptor Beta in the Ventromedial Hypothalamus Is Essential for the Physiological Regulation of Food Intake and Body Weight
Hameed, S., Patterson, M., Dhillo, W.S., Rahman, S.A., Ma, Y., Holton, C., Gogakos, A., Yeo, G.S.H., Lam, B.Y.H., Polex-Wolf, J., Fenske, W., Bell, J.D., Anastasovska, J., Samarut, J., Bloom, S.R., Bassett, J.H.D., Williams, G.R. and Gardiner, J.V. 2017. Thyroid Hormone Receptor Beta in the Ventromedial Hypothalamus Is Essential for the Physiological Regulation of Food Intake and Body Weight. Cell Reports. 19 (11), pp. 2202-2219. https://doi.org/10.1016/j.celrep.2017.05.066

A Framework for Morphological Feature Extraction of Organs from MR Images for Detection and Classification of Abnormalities
Villarini, B., Asaturyan, H., Thomas, E.L., Mould, R. and Bell, J.D. 2017. A Framework for Morphological Feature Extraction of Organs from MR Images for Detection and Classification of Abnormalities. Proceedings of the 30th IEEE International Symposium on Computer-Based Medical Systems (CBMS’17). Thessaloniki, Greece 22 - 24 Jun 2017 IEEE . https://doi.org/10.1109/CBMS.2017.49

Interpretability indices for hierarchical fuzzy systems
Razak, T.R., Garibaldi, J.M., Wagner, C., Pourabdollah, A. and Soria, D. 2017. Interpretability indices for hierarchical fuzzy systems. IEEE International Conference on Fuzzy Systems (FUZZ-IEEE 2017). Naples, Italy 09 - 12 Jul 2017 IEEE . https://doi.org/10.1109/FUZZ-IEEE.2017.8015616

Ensemble Risk Model of Emergency Admissions (ERMER)
Mesgarpour, M., Chaussalet, T.J. and Chahed, S. 2017. Ensemble Risk Model of Emergency Admissions (ERMER). International Journal of Medical Informatics. 103, pp. 65-77. https://doi.org/10.1016/j.ijmedinf.2017.04.010

Psoas major cross-sectional area: A potential marker of cardiorespiratory fitness
Fitzpatrick, J., Chambers, E.S., Parkinson, J.R.C., Frost, G., Bell, J.D. and Thomas, E.L. 2017. Psoas major cross-sectional area: A potential marker of cardiorespiratory fitness. International Journal of Clinical and Experimental Physiology. 4 (1), pp. 15-20. https://doi.org/10.4103/ijcep.ijcep_6_17

Metabolic dysfunction following weight cycling in male mice
Schofield, S.E., Parkinson, J., Henley, A., Sahuri Arisoylu, M., Sanchez-Canon, G.J. and Bell, J.D. 2017. Metabolic dysfunction following weight cycling in male mice. International Journal of Obesity. 41 (3), pp. 402-411. https://doi.org/10.1038/ijo.2016.193

Characterisation of liver fat in the UK Biobank cohort
Wilman, H., Kelly, M., Garratt, S., Matthews, P., Milanesi, M., Herlihy, A.H., Gyngell, M, Neubauer, S, Bell, J.D., Banerjee, R and Thomas, E.L. 2017. Characterisation of liver fat in the UK Biobank cohort. PLoS ONE. 12 (2) e0172921. https://doi.org/10.1371/journal.pone.0172921

Withania somnifera Root Extract Enhances Chemotherapy through ‘Priming’
Henley, A., Yang L., Chuang K-L., Sahuri Arisoylu, M., Wu, L-H., Bligh, S.W.A. and Bell, J.D. 2017. Withania somnifera Root Extract Enhances Chemotherapy through ‘Priming’. PLoS ONE. 12 (1) e0170917. https://doi.org/10.1371/journal.pone.0170917

Cellular glycosylation affects Herceptin binding and sensitivity of breast cancer cells to doxorubicin and growth factors
Peiris, D., Spector, A.F., Lomax-Browne, H., Azimi, T., Ramesh, B., Loizidou, M., Welch, H. and Dwek, M. 2017. Cellular glycosylation affects Herceptin binding and sensitivity of breast cancer cells to doxorubicin and growth factors. Scientific Reports. 7 43006. https://doi.org/10.1038/srep43006

Towards a threshold climate for emergency lower respiratory hospital admissions
Islam, M.S., Chaussalet, T.J. and Koizumi, N. 2017. Towards a threshold climate for emergency lower respiratory hospital admissions. Environmental Research. 153, pp. 41-47. https://doi.org/10.1016/j.envres.2016.11.011

Balanced translocation linked to psychiatric disorder, glutamate, and cortical structure/function.
Thomson, P.A., Duff, B., Blackwood, D.H., Romaniuk, L., Watson, A., Whalley, H.C., Li, X., Dauvermann, M.R., Moorhead, T.W., Bois, C., Ryan, N.M., Redpath, H., Hall, L., Morris, S.W., van Beek, E.J., Roberts, N., Porteous, D.J., St Clair, D., Whitcher, B. and Dunlop, J. 2016. Balanced translocation linked to psychiatric disorder, glutamate, and cortical structure/function. Schizophrenia. 2 16024. https://doi.org/10.1038/npjschz.2016.24

Dissociation between exercise-induced reduction in liver fat and changes in hepatic and peripheral glucose homoeostasis in obese patients with non-alcoholic fatty liver disease
Cuthbertson, D.J., Shojaee-Moradie, F., Sprung, V.S., Jones, H., Pugh, C.J.A., Richardson, P., Kemp, G.J., Barrett, M., Jackson, N.C., Thomas, E.L., Bell, J.D. and Umpleby, M. 2016. Dissociation between exercise-induced reduction in liver fat and changes in hepatic and peripheral glucose homoeostasis in obese patients with non-alcoholic fatty liver disease. Clinical Science. 130 (2), pp. 93-104. https://doi.org/10.1042/cs20150447

Validation of a quantifier-based fuzzy classification system for breast cancer patients on external independent cohorts
Soria, D. and Garibaldi, J.M. 2016. Validation of a quantifier-based fuzzy classification system for breast cancer patients on external independent cohorts. IEEE International Conference on Machine Learning and Applications (ICMLA2016). Anaheim, California, USA 18 - 20 Dec 2016 IEEE . https://doi.org/10.1109/ICMLA.2016.0101

Nottingham Prognostic Index Plus: Validation of a clinical decision making tool in breast cancer in an independent series
Green, A.R., Soria, D., Stephen, J., Powe, D.G., Nolan, C.C., Kunkler, I., Thomas, J., Kerr, G.R., Jack, W., Cameron, D., Piper, T., Ball, G.R., Garibaldi, J.M., Rakha, E.A., Bartlett, J.M.S. and Ellis, I.O. 2016. Nottingham Prognostic Index Plus: Validation of a clinical decision making tool in breast cancer in an independent series. The Journal of Pathology: Clinical Research. 1 (2), pp. 32-40. https://doi.org/10.1002/cjp2.32

Illness Beliefs Predict Mortality in Patients with Diabetic Foot Ulcers
Vedhara, K., Dawe, K., Miles, J.N.V., Wetherell, M.A., Cullum, N., Dayan, C., Drake, N., Price, P., Tarlton, J., Weinman, J., Day, A., Campbell, R., Reps, J. and Soria, D. 2016. Illness Beliefs Predict Mortality in Patients with Diabetic Foot Ulcers. PLoS ONE. 11 (4) e0153315. https://doi.org/10.1371/journal.pone.0153315

Nottingham prognostic index plus (NPI+) predicts risk of distant metastases in primary breast cancer
Green, A.R., Soria, D., Powe, G., Nolan, C.C., Aleskandarany, N.M., Szász, M.A., Tőkés, A.M., Ball, G.R., Garibaldi, J.M., Rakha, E.A., Kulka, J. and Ellis, I.O. 2016. Nottingham prognostic index plus (NPI+) predicts risk of distant metastases in primary breast cancer. Breast Cancer Research and Treatment. 157 (1), pp. 65-75. https://doi.org/10.1007/s10549-016-3804-1

KI67 and DLX2 predict increased risk of metastasis formation in prostate cancer–a targeted molecular approach
Green, W.J.F., Ball, G., Hulman, G., Johnson, C., Van Schalwyk, G., Ratan, H.L., Soria, D., Garibaldi, J.M., Parkinson, R., Hulman, J., Rees, R. and Powe, D.G. 2016. KI67 and DLX2 predict increased risk of metastasis formation in prostate cancer–a targeted molecular approach. British Journal of Cancer. 115 (2), pp. 236-242. https://doi.org/10.1038/bjc.2016.169

Cancer subtype identification pipeline: A classifusion approach
Agrawal, U., Soria, D. and Wagner, C. 2016. Cancer subtype identification pipeline: A classifusion approach. Evolutionary Computation (CEC), 2016 IEEE Congress on. 24 - 29 Jul 2016 IEEE . https://doi.org/10.1109/CEC.2016.7744150

Effect of energy restriction and physical exercise intervention on phenotypic flexibility as examined by transcriptomics analyses of mRNA from adipose tissue and whole body magnetic resonance imaging
Lee, S., Norheim, F., Langleite, T.M., Noreng, H.J., Storås, T.H., Afman, L.A., Frost, G., Bell, J.D., Thomas, E.L., Kolnes, K.J., Tangen, D.S., Stadheim, H.K., Gilfillan, G.D., Gulseth, H.L., Birkeland, K.I., Jensen, J., Drevon, C.A. and Holen, T. 2016. Effect of energy restriction and physical exercise intervention on phenotypic flexibility as examined by transcriptomics analyses of mRNA from adipose tissue and whole body magnetic resonance imaging. Physiological Reports. 4 (21), p. e13019 e13019. https://doi.org/10.14814/phy2.13019

Feasibility of MR-Based Body Composition Analysis in Large Scale Population Studies
West, J., Leinhard, O.D., Romu, T., Collins, R., Garratt, S., Bell, J.D., Borga, M. and Thomas, E.L. 2016. Feasibility of MR-Based Body Composition Analysis in Large Scale Population Studies. PLoS ONE. 11 (9) e0163332. https://doi.org/10.1371/journal.pone.0163332

Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus
Zeng, C., Guo, X., Long, J., Kuchenbaecker, K.B., Droit, A., Michailidou, K., Ghoussaini, M., Kar, S., Freeman, A., Hopper, J.L., Milne, R.L., Bolla, M.K., Wang, Q., Dennis, J., Agata, S., Ahmed, S., Aittomaki, K., Andrulis, I.L., Anton-Culver, H., Antonenkova, N.N., Arason, A., Arndt, V., Arun, B.K., Arver, B., Bacot, F., Barrowdale, D., Baynes, C., Beeghly-Fadiel, A., Benitez, J., Bermisheva, M., Blomqvist, C., Blot, W.J., Bogdanova, N.V., Bojesen, S.E., Bonanni, B., Borresen-Dale, A.-L., Brand, J.S., Brauch, H., Brennan, P., Brenner, H., Broeks, A., Brüning, T., Burwinkel, B., Buys, S.S., Cai, Q., Caldes, T., Campbell, I., Carpenter, J., Chang-Claude, J., Choi, J.Y., Claes, K.B.M., Clarke, C., Cox, A., Cross, S.S., Czene, K., Daly, M.B., de la Hoya, M., De Leeneer, K., Devilee, P., Diez, O., Domchek, S.M., Doody, M.M., Dorfling, C.M., Dörk, T., Dos Santos Silva, I., Dumont, M., Dwek, M., Dworniczak, B., Egan, K.M., Eilber, U., Einbeigi, Z., Ejlertsen, B., Ellis, S., Frost, D., Lalloo, F., Fasching, P.A., Figueroa, J.D., Flyger, H., Friedlander, M., Friedman, E., Gambino, G., Gao, Y.T., Garber, J., Garcia-Closas, M., Gehrig, A., Damiola, F., Lesueur, F., Mazoyer, S., Stoppa-Lyonnet, D., Giles, G.G., Godwin, A.K., Goldgar, D.E., González-Neira, A., Greene, M.H., Guenel, P., Haeberle, L., Haiman, C.A., Hallberg, E., Hamann, U., Hansen, T.V.O., Hart, S., Hartikainen, J.M., Hartman, M., Hassan, N., Healey, S., Hogervorst, F.B.L., Verhoef, S., Hendricks, C.B., Hillemanns, P., Hollestelle, A., Hulick, P.J., Hunter, D.J., Imyanitov, E.N., Isaacs, C., Ito, H., Jakubowska, A., Janavicius, R., Jaworska-Bieniek, K., Jensen, U.B., John, E.M., Beauparlant, C.J., Jones, M., Kabisch, M., Kang, D., Karlan, B.Y., Kauppila, S., Kerin, M.J., Khan, S., Khusnutdinova, E., Knight, J.A., Konstantopoulou, I., Kraft, P., Kwong, A., Laitman, Y., Lambrechts, D., Lazaro, C., Le Marchand, L., Lee, C.N., Lee, M.H., Lester, J., Li, J., Liljegren, A., Lindblom, A., Lophatananon, A., Lubinski, J., Mai, P.L., Mannermaa, A., Manoukian, S., Margolin, S., Marme, F., Matsuo, K., McGuffog, L., Meindl, A., Menegaux, F., Montagna, M., Muir, K., Mulligan, A.M., Nathanson, K.L., Neuhausen, S.L., Nevanlinna, H., Newcomb, P.A., Nord, S., Nussbaum, R.L., Offit, K., Olah, E., Olopade, O.I., Olswold, C., Osorio, A., Papi, L., Park-Simon, T.W., Paulsson-Karlsson. Y., Peeters, S., Peissel, B., Peterlongo, P., Peto, J., Pfeiler, G., Phelan, C.M., Presneau, Nadège, Presneau, N., Radice, P., Rahman, N., Ramus, S.J., Rashid, M.U., Rennert, G., Rhiem, K., Rudolph, A., Salani, R., Sangrajrang, S., Sawyer, E.J., Schmidt, M.K., Schmutzler, R.K., Schoemaker, M.J., Schürmann, P., Seynaeve, C., Shen, C.Y., Shrubsole, M.J., Shu, X.O., Sigurdson, A., Singer, C.F., Slager, S., Soucy, P., Southey, M., Steinemann, D., Swerdlow, A., Szabo, C.I., Tchatchou, S., Teixeira, M.R., Teo, S.H., Terry, M.B., Tessier, D.C., Teulé, A., Thomassen, M., Tihomirova, L., Tischkowitz, M., Toland, A.E., Tung, N., Turnbull, C., van den Ouweland, A.M., van Rensburg, E.J., Ven den Berg, D., Vijai, J., Wang-Gohrke, S., Weitzel, J.N., Whittemore, A.S., Winqvist, R., Wong, T.Y., Wu, A.H., Yannoukakos, D., Yu, J.C., Pharoah, P.D., Hall, P., Chenevix-Trench, G., Dunning, A.M., Simard, J., Couch, F.J., Antoniou, A.C., Easton, D.F., Antoniou, A.C. and Zheng, W. 2016. Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus. Breast Cancer Research. 18 (1), p. 64. https://doi.org/10.1186/s13058-016-0718-0

The Quantum Mitochondrion and Optimal Health
Bell, J.D., Nunn, A.V.W. and Guy, G.W. 2016. The Quantum Mitochondrion and Optimal Health. Biochemical Society Transactions. 44 (4), pp. 1101-1110. https://doi.org/10.1042/BST20160096

Link between increased gut hormones signaling satiety and reduced food reward following gastric bypass surgery for obesity
Goldstone, A.P., Miras, A.D., Scholtz, S., Jackson, S., Neff, K.J., Pénicaud, L., Geoghegan, J., Chhina, N., Durighel, G., Bell, J.D., Meillon, S. and le Roux, C.W. 2016. Link between increased gut hormones signaling satiety and reduced food reward following gastric bypass surgery for obesity. Journal of Clinical Endocrinology and Metabolism. 101 (2), pp. 599-609. https://doi.org/10.1210/jc.2015-2665

Synergy between histone deacetylase inhibitors and DNA- damaging agents is mediated by histone deacetylase 2 in colorectal cancer
Alzoubi, S., Brody, L., Rahman, S., Mahul-Mellier, A.L., Mercado, N., Ito, K., El-Bahrawy, M., Silver, A., Boobis, A., Bell, J.D. and Hajji, N. 2016. Synergy between histone deacetylase inhibitors and DNA- damaging agents is mediated by histone deacetylase 2 in colorectal cancer. Oncotarget . 7 (28), pp. 44505-44521. https://doi.org/10.18632/oncotarget.9887

Exercise Training Reduces Liver Fat and Increases Rates of VLDL Clearance, but not VLDL Production in NAFLD
Shojaee-Moradie, F., Cuthbertson, D.J., Barrett, M., Jackson, N.C., Herring, R, Thomas, E.L., Bell, J.D., Kemp, G.J., Wright, J. and Umpleby, A.M. 2016. Exercise Training Reduces Liver Fat and Increases Rates of VLDL Clearance, but not VLDL Production in NAFLD. Journal of Clinical Endocrinology and Metabolism. 101 (11), pp. 4219-4228. https://doi.org/10.1210/jc.2016-2353

Efficacy and Safety of Cannabidiol and Tetrahydrocannabivarin on Glycemic and Lipid Parameters in Patients With Type 2 Diabetes: A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Pilot Study
Jadoon, K.A., Ratcliffe, S.H., Barrett, D.A., Thomas, E.L., Stott, C., Bell, J.D., O’Sullivan S.E. and Tan, G.D. 2016. Efficacy and Safety of Cannabidiol and Tetrahydrocannabivarin on Glycemic and Lipid Parameters in Patients With Type 2 Diabetes: A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Pilot Study. Diabetes Care. 39 (10), pp. 1777-1786. https://doi.org/10.2337/dc16-0650

A general framework for Business Process Modelling (BPM) based on Formal Temporal Theory with an application to Hospital Patient flows
Chishti, I., Chaussalet, T.J. and Basukoski, A. 2016. A general framework for Business Process Modelling (BPM) based on Formal Temporal Theory with an application to Hospital Patient flows. 8th IMA International Conference on Quantitative Modelling in the Management of Health and Social Care. Asia House, London 21 - 23 Mar 2016 Institute of Mathematics and its Applications.

Business Process Modelling based on formal temporal theory with an application to hospital patient flows
Chishti, I., Basukoski, A. and Chaussalet, T.J. 2016. Business Process Modelling based on formal temporal theory with an application to hospital patient flows. 8th IMA International Conference on Quantitative Modelling in the Management of Health and Social Care. Asia House, London 21 - 23 Mar 2016 Institute of Mathematics and its Applications.

Risk Modelling Framework for Emergency Hospital Readmission, Using Hospital Episode Statistics Inpatient Data
Mesgarpour, M., Chaussalet, T.J. and Chahed, S. 2016. Risk Modelling Framework for Emergency Hospital Readmission, Using Hospital Episode Statistics Inpatient Data. IEEE 29th International Symposium on Computer-Based Medical Systems. Dublin and Belfast 20 - 23 Jun 2016 IEEE . https://doi.org/10.1109/CBMS.2016.21

Predictive Risk Modelling for Integrated Care: a Structured Review
Mesgarpour, M., Chaussalet, T.J., Worrall, P. and Chahed, S. 2016. Predictive Risk Modelling for Integrated Care: a Structured Review. IEEE 29th International Symposium on Computer-Based Medical Systems. Dublin and Belfast 20 - 23 Jun 2016 IEEE . https://doi.org/10.1109/CBMS.2016.34

Nutritional Evaluation and Optimisation in Neonates: a randomized, double-blind controlled trial of amino acid regimen and intravenous lipid composition in preterm parenteral nutrition
Uthaya, S.N., Liu, X., Babalis, D., Doré, C.J., Caroline, J., Warwick, J., Bell, J.D., Thomas, E.L., Ashby, D., Durighel, G., Ederies, A., Yanez-Lopez, M. and Modi, N. 2016. Nutritional Evaluation and Optimisation in Neonates: a randomized, double-blind controlled trial of amino acid regimen and intravenous lipid composition in preterm parenteral nutrition. American Journal of Clinical Nutrition. 106 (3), pp. 1443-1452. https://doi.org/10.3945/ajcn.115.125138

Cadherin-5: a biomarker for metastatic breast cancer with optimum efficacy in oestrogen receptor-positive breast cancers with vascular invasion
Fry, S., Robertson, C.E., Swann, R. and Dwek, M. 2016. Cadherin-5: a biomarker for metastatic breast cancer with optimum efficacy in oestrogen receptor-positive breast cancers with vascular invasion. British Journal of Cancer. 114, pp. 1019-1026. https://doi.org/10.1038/bjc.2016.66

Nutritional Evaluation and Optimisation in Neonates (NEON) trial of amino acid regimen and intravenous lipid composition in preterm parenteral nutrition: a randomised double-blind controlled trial
Uthaya, S.N., Liu, X., Babalis, D., Doré, C.J., Warwick, J., Bell, J.D., Thomas, E.L., Ashby, D., Durighel, G., Ederies, A., Yanez-Lopez, M. and Modi, N. 2016. Nutritional Evaluation and Optimisation in Neonates (NEON) trial of amino acid regimen and intravenous lipid composition in preterm parenteral nutrition: a randomised double-blind controlled trial. Efficacy and Mechanism Evaluation. 3 (2). https://doi.org/10.3310/eme03020

Reprogramming of hepatic fat accumulation and 'browning' of adipose tissue by the short-chain fatty acid acetate
Sahuri Arisoylu, M., Brody, L., Parkinson, J., Parkes, H.G., Navaratnam, N., Miller, A.D., Thomas, E.L., Frost, G.S. and Bell, J.D. 2016. Reprogramming of hepatic fat accumulation and 'browning' of adipose tissue by the short-chain fatty acid acetate. International Journal of Obesity. 40, p. 955–963. https://doi.org/10.1038/ijo.2016.23

Liver fat in adults with GH deficiency: comparison to matched controls and the effect of GH replacement
Meienberg, F., Yee, M., Johnston, D.G., Cox, J., Robinson, S., Bell, J.D., Thomas, E.L., Taylor-Robinson, S.D. and Godsland, I.F. 2016. Liver fat in adults with GH deficiency: comparison to matched controls and the effect of GH replacement. Clinical Endocrinology. 85 (1), pp. 76-84. https://doi.org/10.1111/cen.13042

Efficacy of DOPE/DC-cholesterol liposomes and GCPQ micelles as AZD6244 nanocarriers in a 3D colorectal cancer in vitro model
López-Dávila, V., Magdeldin, T., Welch, H., Dwek, M., Uchegbu, I. and Loizidou, M. 2016. Efficacy of DOPE/DC-cholesterol liposomes and GCPQ micelles as AZD6244 nanocarriers in a 3D colorectal cancer in vitro model. Nanomedicine. 11 (4), pp. 331-344. https://doi.org/10.2217/nnm.15.206

Is the NHS in England too big to fail?
Dalton, S., Chahed, S. and Chaussalet, T.J. 2016. Is the NHS in England too big to fail? 8th Institute of Mathematics and Its Applications. Asia House, London 21 Mar 2016

Single-dose serotonergic stimulation shows widespread effects on functional brain connectivity
Klaassens, B.L., van Gorsel, H.C., Khalili-Mahani, N., van der Grond, J., Wyman, B.T., Whitcher, B., Rombouts, S.A.R.B. and van Gerven, J.M.A. 2015. Single-dose serotonergic stimulation shows widespread effects on functional brain connectivity. NeuroImage. 122, pp. 440-450. https://doi.org/10.1016/j.neuroimage.2015.08.012

The cortical thickness phenotype of individuals with DISC1 translocation resembles schizophrenia
Doyle, O.M., Bois, C., Thomson, P., Romaniuk, L., Whitcher, B., Williams, S.C.R., Turkheimer, F.E., Stefansson, H., McIntosh, A.M., Mehta, M.A. and Lawrie, S.M. 2015. The cortical thickness phenotype of individuals with DISC1 translocation resembles schizophrenia. Journal of Clinical Investigation. 125 (9), pp. 3714-3722. https://doi.org/10.1172/jci82636

Effects of a balanced translocation between chromosomes 1 and 11 disrupting the DISC1 locus on white matter integrity
Whalley, H.C., Dimitrova, R., Sprooten, E., Dauvermann, M.R., Romaniuk, L., Duff, B., Watson, A.R., Moorhead, B., Bastin, M., Semple, S.I., Giles, S., Hall, J., Thomson, P., Roberts, N., Hughes, Z.A., Brandon, N.J., Dunlop, J., Whitcher, B., Blackwood, D.H.R., McIntosh, A.M. and Lawrie, S.M. 2015. Effects of a balanced translocation between chromosomes 1 and 11 disrupting the DISC1 locus on white matter integrity. PLoS ONE. 10 (6) e0130900. https://doi.org/10.1371/journal.pone.0130900

A structured review of long-term care demand modelling
Worrall, P. and Chaussalet, T.J. 2015. A structured review of long-term care demand modelling. Health Care Management Science. 18 (2), pp. 173-194. https://doi.org/10.1007/s10729-014-9299-6

Markers of Progression in Early-Stage Invasive Breast Cancer: a Predictive Immunohistochemical Panel Algorithm for Distant Recurrence Risk Stratification
Aleskandarany, M.A., Soria, D., Green, A.R., Nolan, C., Diez-Rodriguez, M., Ellis, I.O. and Rakha, E.A. 2015. Markers of Progression in Early-Stage Invasive Breast Cancer: a Predictive Immunohistochemical Panel Algorithm for Distant Recurrence Risk Stratification. Breast Cancer Research and Treatment. 151 (2), pp. 325-333. https://doi.org/10.1007/s10549-015-3406-3

Improving the NHS demands more than just extra money [Letter]
Young, T., Brailsford, S., Berry, R., Braun, H., Cordeaux, C., Chaussalet, T.J., Davies, K., Debenedetti, L., Farrar, M., Harper, P.R., King, J., Lacey, P., Lyon, J., Marshall, A., McClean, S., McKelvie, D., Pollard, A., Schmidt, P. and Soorapanth, S. 2015. Improving the NHS demands more than just extra money [Letter]. BMJ. 350, p. h3338. https://doi.org/10.1136/bmj.h3338

Body fat MRS
Thomas, E.L. and Bell, J.D. 2015. Body fat MRS. eMagRes. 4 (3), pp. 663-672. https://doi.org/10.1002/9780470034590.emrstm1478

A randomized controlled trial: the effect of inulin on weight management and ectopic fat in subjects with prediabetes.
Guess, N.D., Dornhorst, A., Oliver, N., Bell, J.D., Thomas, E.L. and Frost, G.S. 2015. A randomized controlled trial: the effect of inulin on weight management and ectopic fat in subjects with prediabetes. Nutrition & Metabolism. 12 (36). https://doi.org/10.1186/s12986-015-0033-2

The Breast Cancer Cookbook
Keshtgar, M., Robertson, C.E. and Dwek, M. Keshtgar, M. (ed.) 2015. The Breast Cancer Cookbook. London Quadrille.

Validation of a fast method for quantification of intra-abdominal and subcutaneous adipose tissue for large-scale human studies
Borga, M., Thomas, E.L., Romu, T., Rosander, J., Fitzpatrick, J., Leinhard, O.D., Bell, J.D. and Borger Magnus 2015. Validation of a fast method for quantification of intra-abdominal and subcutaneous adipose tissue for large-scale human studies. NMR in Biomedicine. 28 (12), pp. 1747-1753. https://doi.org/10.1002/nbm.3432

Dissociation between exercise-induced reduction in liver fat and changes in hepatic and peripheral glucose homeostasis in obese patients with Non-Alcoholic Fatty Liver Disease.
Cuthbertson, D.J., Shojaee-Moradie, F., Sprung, V.S., Jones, H., Pugh, C.J., Richardson, P., Kemp, G.J., Barrett, M., Jackson, N.C., Thomas, E.L., Bell, J.D. and Umpleby, A.M. 2015. Dissociation between exercise-induced reduction in liver fat and changes in hepatic and peripheral glucose homeostasis in obese patients with Non-Alcoholic Fatty Liver Disease. Clinical Science. 130 (2), pp. 93-104. https://doi.org/10.1042/CS20150447

Effects of targeted delivery of propionate to the human colon on appetite regulation, body weight maintenance and adiposity in overweight adults.
Chambers, E.S., Viardot, A., Psichas, A., Morrison, D.J., Murphy, K.G., Zac-Varghese, S.E., MacDougall, K., Preston, T., Tedford, C., Finlayson, G.S., Blundell, J.E., Bell, J.D., Thomas, E.L., Mt-Isa, S., Ashby, D., Gibson, G.R., Kolida, S., Dhillo, W.S., Bloom, S.R., Morley, W., Clegg, S., Frost, G.S. and Sagen E K Zac-Varghese 2015. Effects of targeted delivery of propionate to the human colon on appetite regulation, body weight maintenance and adiposity in overweight adults. Gut. 64 (11), pp. 1744-54. https://doi.org/10.1136/gutjnl-2014-307913

Identification of O-Linked Glycoproteins Binding to the Lectin Helix pomatia Agglutinin as Markers of Metastatic Colorectal Cancer
Peiris, D., Ossondo, M., Fry, S., Loizidou, M., Smith-Ravin, J. and Dwek, M. 2015. Identification of O-Linked Glycoproteins Binding to the Lectin Helix pomatia Agglutinin as Markers of Metastatic Colorectal Cancer. PLoS ONE. 10 (10) e0138345. https://doi.org/10.1371/journal.pone.0138345

Toward simulating the english neonatal unit
Dalton, S., Chahed, S. and Chaussalet, T.J. 2015. Toward simulating the english neonatal unit. 27th European Conference on Operational Reasearch (EURO). University of Strathclyde, Glasgow 13 Jul 2015

Prediction of breast cancer risk based on profiling with common genetic variants
Mavaddat, N., Pharoah, P.D.P., Michailidou, K., Tyrer, J., Brook, M.N., Bolla, M.K., Wang, Q., Dennis, J., Dunning, A.M., Shah, M., Luben, R., Brown, J.C.C., Bojesen, S.E., Nordestgaard, B.G., Nielsen, S.F., Flyger, H., Czene, K., Darabi, H., Eriksson, M., Peto, J., Dos-Santos-Silva, I., Dudbridge, F., Johnson, N., Schmidt, M.K., Broeks, A., Verhoef, S., Rutgers, E.J., Swerdlow, A.J., Ashworth, A., Orr, N., Schoemaker, M.J., Figueroa, J.D., Chanock, S.J., Brinton, L., Lissowska, J., Couch, F.J., Olson, J.E., Vachon, C., Pankratz, V.S., Lambrechts, D., Wildiers, H., Van Ongeval, C., van Limbergen, E., Kristensen, V., Grenaker Alnaes, G., Nord, S., Borresen-Dale, A.-L., Nevanlinna, H., Muranen, T.A., Aittomaki, K., Blomqvist, C., Chang-Claude, J., Rudolph, A., Seibold, P., Flesch-Janys, D., Fasching, P.A., Haeberle, L., Ekici, A.B., Beckmann, M.W., Burwinkel, B., Marme, F., Schneeweiss, A., Sohn, C., Trentham-Dietz, A., Newcomb, P., Titus, L., Egan, K.M., Hunter, D.J., Lindstrom, S., Tamimi, R.M., Kraft, P., Rahman, N., Turnbull, C., Renwick, A., Seal, S., Li, J., Liu, J., Humphreys, K., Benitez, J., Pilar Zamora, M., Arias Perez, J.I., Menéndez, P., Jakubowska, A., Lubinski, J., Jaworska-Bieniek, K., Durda, K., Bogdanova, N.V., Antonenkova, N.N., Dörk, T., Anton-Culver, H., Neuhausen, S.L., Ziogas, A., Bernstein, L., Devilee, P., Tollenaar, R.A.E.M., Seynaeve, C., van Asperen, C.J., Cox, A., Cross, S.S., Reed, M.W., Khusnutdinova, E., Bermisheva, M., Prokofyeva, D., Takhirova, Z., Meindl, A., Schmutzler, R.K., Sutter, C., Yang, R., Schürmann, P., Bremer, M., Christiansen, H., Park-Simon, T.-W., Hillemanns, P., Guenel, P., Truong, T., Menegaux, F., Sanchez, M., Radice, P., Peterlongo, P., Manoukian, S., Pensotti, V., Hopper, J.L., Tsimiklis, H., Apicella, C., Southey, M.C., Brauch, H., Brüning, T., Ko, Y.-D., Sigurdson, A.J., Doody, M.M., Hamann, U., Torres, D., Ulmer, H.U., Försti, A., Sawyer, E., Tomlinson, I., Kerin, M.J., Miller, N., Andrulis, I.L., Knight, J.A., Glendon, G., Marie Mulligan, A., Chenevix-Trench, G., Balleine, R., Giles, G.G., Milne, R.L., McLean, C.A., Lindblom, A., Margolin, S., Haiman, C.A., Henderson, B.E., Schumacher, F., Le Marchand, L., Eilber, U., Wang-Gohrke, S., Hooning, M.J., Hollestelle, A., van den Ouweland, A.M.W., Koppert, L.B., Carpenter, J., Clarke, C., Scott, R., Mannermaa, A., Kataja, V., Kosma, V.-M., Hartikainen, J.M., Brenner, H., Arndt, V., Stegmaier, C., Karina Dieffenbach, A., Winqvist, R., Pylkas, K., Jukkola-Vuorinen, A., Grip, M., Offit, K., Vijai, J., Robson, M., Rau-Murthy, R., Dwek, M., Swann, R., Annie Perkins, K., Goldberg, M.S., Labrèche, F., Dumont, M., Eccles, D.M., Tapper, W.J., Rafiq, S., John, E.M., Whittemore, A.S., Slager, S., Yannoukakos, D., Toland, A.E., Yao, S., Zheng, W., Halverson, S.L., Gonzalez-Neira, A., Pita, G., Rosario Alonso, M., Álvarez, N., Herrero, D., Tessier, D.C., Vincent, D., Bacot, F., Luccarini, C., Baynes, C., Ahmed, S., Maranian, M., Healey, C.S., Simard, J., Hall, P., Easton, D.F., Garcia-Closas, M., Dos Santos Silva, I., Channock, S.J., Zamora, M.P., Ignacio Arias Perez, J., Neuhasen, S.L., Prokofieva, D., Mulligan, A.M., Halman, C.A., Dieffenbach, A.K., Perkins, K.A. and Alonso, M.R. 2015. Prediction of breast cancer risk based on profiling with common genetic variants. Journal of the National Cancer Institute. 107 (5). https://doi.org/10.1093/jnci/djv036

Circulating pancreatic polypeptide concentrations predict visceral and liver fat content
Sam Amir, H., Sleeth Michelle, L., Thomas, E.L., Daud Norlida, M., Chambers, Edward, Shojaee-Moradie, Fariba, Umpleby, A.M., le Roux, C.W., Bech, Paul, Busbridge, Mark, Laurie, Rosemary Cuthbertson Daniel, J., Buckley, Adam, Bloom, S.R., Frost, G.S., Bell, J.D., Murphy, K.G., Ismail, Nurhafzan, Shoajee-Moradie, Fariba, Goldstone, A.P., Cuthbertson, D.J. and Ghatei, M.A. 2015. Circulating pancreatic polypeptide concentrations predict visceral and liver fat content. Journal of Clinical Endocrinology and Metabolism. 100 (3), pp. 1048-1052. https://doi.org/10.1210/jc.2014-3450

Sexual dimorphism in relation to adipose tissue and intrahepatocellular lipid deposition in early infancy
Gale, C., Jeffries, Suzan, Santhakumaran, S., Uthaya, S.N., Durighel, G., Alavi, Afshin, Modi, N., Thomas, E.L., Logan, Karen M., Parkinson, J.R.C. and Bell, J.D. 2015. Sexual dimorphism in relation to adipose tissue and intrahepatocellular lipid deposition in early infancy. International Journal of Obesity. 39 (4), pp. 629-32. https://doi.org/10.1038/ijo.2015.4

Automated identification of brain new lesions in multiple sclerosis using subtraction images
Battaglini, M., Rossi, F., Grove, R.A., Stromillo, M.L., Whitcher, B., Matthews, P.M. and De Stefano, N. 2014. Automated identification of brain new lesions in multiple sclerosis using subtraction images. Journal of Magnetic Resonance Imaging. 39 (6), pp. 1543-1549. https://doi.org/10.1002/jmri.24293

Genetic predisposition to in situ and invasive lobular carcinoma of the breast.
Sawyer, E., Roylance, R., Petridis, C., Brook, M.N., Nowinski, S., Papouli, E., Fletcher, O., Pinder, S., Hanby, A., Kohut, K., Gorman, P., Caneppele, M., Peto, J., Garcia-Closas, M. and Dwek, M. 2014. Genetic predisposition to in situ and invasive lobular carcinoma of the breast. PLoS genetics. 10 (4) e1004285. https://doi.org/10.1371/journal.pgen.1004285

Refined histopathological predictors of BRCA1 and BRCA2 mutation status: a large-scale analysis of breast cancer characteristics from the BCAC, CIMBA, and ENIGMA consortia.
Spurdle, A.B., Couch, F.J., Parsons, M.T., McGuffog, L., Barrowdale, D., Bolla, M.K., Wang, Q., Healey, S., Schmutzler, R., Wappenschmidt, B., Rhiem, K., Hahnen, E., Engel, C., kConFab Investigators and Dwek, M. 2014. Refined histopathological predictors of BRCA1 and BRCA2 mutation status: a large-scale analysis of breast cancer characteristics from the BCAC, CIMBA, and ENIGMA consortia. Breast Cancer Research. 16 3419. https://doi.org/10.1186/s13058-014-0474-y

Practical detection of a definitive biomarker panel for Alzheimer’s Disease; comparisons between plasma and cerebrospinal fluid
Richens, J.L., Vere, K.-A., Light, R.A., Soria, D., Garibaldi, J.M., Smith, A.D., Warden, D., Wilcock, G., Bajaj, N., Morgan, K. and O’Shea, P. 2014. Practical detection of a definitive biomarker panel for Alzheimer’s Disease; comparisons between plasma and cerebrospinal fluid. International Journal of Molecular Epidemiology and Genetics. 5 (2), pp. 53-70.

Signalling Paediatric Side Effects using an Ensemble of Simple Study Designs
Reps, J.M., Aickelin, U., Garibaldi, J.M., Soria, D., Gibson, J.E. and Hubbard, R.B. 2014. Signalling Paediatric Side Effects using an Ensemble of Simple Study Designs. Drug Safety. 37 (3), pp. 163-170. https://doi.org/10.1007/s40264-014-0137-z

A Novel Semisupervised Algorithm for Rare Prescription Side Effect Discovery
Reps, J.M., Garibaldi, J.M., Aickelin, U., Soria, D., Gibson, J.E. and Hubbard, R.B. 2014. A Novel Semisupervised Algorithm for Rare Prescription Side Effect Discovery. IEEE Journal of Biomedical and Health Informatics. 18 (2), pp. 537-547. https://doi.org/10.1109/JBHI.2013.2281505

Guest Editorial: Data Mining in Bioinformatics
Reps, J.M., Garibaldi, J.M., Aickelin, U., Soria, D., Gibson, J.E. and Hubbard, R.B. 2014. Guest Editorial: Data Mining in Bioinformatics. IEEE Journal of Biomedical and Health Informatics. 18 (2), p. 483. https://doi.org/10.1109/JBHI.2014.2306988

Nottingham Prognostic Index Plus (NPI+): A Modern Clinical Decision Making Tool in Breast Cancer
Rakha, E., Soria, D., Green, A.R., Lemetre, C., Powe, D.G., Nolan, C.C., Garibaldi, J.M., Ball, G.R. and Ellis, I.O. 2014. Nottingham Prognostic Index Plus (NPI+): A Modern Clinical Decision Making Tool in Breast Cancer. British Journal of Cancer. 110 (7), pp. 1688-1697. https://doi.org/10.1038/bjc.2014.120

A methodology for automatic classification of breast cancer immunohistochemical data using semi-supervised Fuzzy c-Means
Lai, D.T.C., Garibaldi, J.M., Soria, D. and Roadknight, C.M. 2014. A methodology for automatic classification of breast cancer immunohistochemical data using semi-supervised Fuzzy c-Means. Central European Journal of Operations Research. 22 (3), pp. 475-499. https://doi.org/10.1007/s10100-013-0318-3

Functional Studies On Receptor-Type Protein Tyrosine Phosphatases Of The R3 Subgroup Using Bimolecular Fluorescence Complementation (BiFC) Assays
Dorofejeva, O., Dwek, M. and Barr, A.J. 2014. Functional Studies On Receptor-Type Protein Tyrosine Phosphatases Of The R3 Subgroup Using Bimolecular Fluorescence Complementation (BiFC) Assays . Pharmacology 2014. London 16 Dec 2014 British Pharmacological Society.

Preterm nutritional intake and MRI phenotype at term age: a prospective observational study
Vasu, V., Durighel, G., Malamateniou, C., Rutherford, M.A., Modi, N., Thomas, E.L. and Bell, J.D. 2014. Preterm nutritional intake and MRI phenotype at term age: a prospective observational study. BMJ Open. 4 (5) e005390. https://doi.org/10.1136/bmjopen-2014-005390

Body Fat: our own Janus
Thomas, E.L. and Bell, J.D. 2014. Body Fat: our own Janus. Physiology News. 96, pp. 24-27. https://doi.org/10.36866/pn.96.24

Multimetallic complexes and functionalized gold nanoparticles based on a combination of d- and f-elements
Sung, S., Holmes, H., Wainwright, L., Toscani, A., Stasiuk, G.J., White, A.J.P., Bell, J.D. and Wilton-Ely, J.D.E.T. 2014. Multimetallic complexes and functionalized gold nanoparticles based on a combination of d- and f-elements. Inorganic Chemistry. 53 (4), pp. 1989-2005. https://doi.org/10.1021/ic401936w

The association between objectively measured sitting and standing with body composition: a pilot study using magnetic resonance imaging
Smith, L., Thomas, E.L., Bell, J.D. and Hamer, M. 2014. The association between objectively measured sitting and standing with body composition: a pilot study using magnetic resonance imaging. BMJ Open. 4 (6) e005476. https://doi.org/10.1136/bmjopen-2014-005476

The intelligence paradox; will ET get the metabolic syndrome? Lessons from and for Earth
Nunn, A.V.W., Guy, G.W. and Bell, J.D. 2014. The intelligence paradox; will ET get the metabolic syndrome? Lessons from and for Earth. Nutrition and Metabolism. 11, p. 34. https://doi.org/10.1186/1743-7075-11-34

A review of dynamic Bayesian network techniques with applications in healthcare risk modelling
Mesgarpour, M., Chaussalet, T.J. and Chahed, S. 2014. A review of dynamic Bayesian network techniques with applications in healthcare risk modelling. 4th Student Conference on Operational Research (SCOR14). Nottingham, UK May 2–4, 2014 Schloss Dagstuhl - Leibniz-Zentrum fuer Informatik. https://doi.org/10.4230/OASIcs.SCOR.2014.89

External validation of the fatty liver index and lipid accumulation product indices, using 1H-magnetic resonance spectroscopy, to identify hepatic steatosis in healthy controls and obese, insulin-resistant individuals
Cuthbertson, D.J., Weickert, M.O., Lythgoe, D., Sprung, V.S., Dobson, R., Shoajee-Moradie Fariba, Umpleby, A.M., Pfeiffer, A.F.H., Thomas, E.L., Bell, J.D., Jones, H. and Kemp, G.J. 2014. External validation of the fatty liver index and lipid accumulation product indices, using 1H-magnetic resonance spectroscopy, to identify hepatic steatosis in healthy controls and obese, insulin-resistant individuals. European Journal of Endocrinology. 171 (5), pp. 561-569. https://doi.org/10.1530/EJE-14-0112

Efficacy of increased resistant starch consumption in human type 2 diabetes
Bodinham, C.L., Smith, L., Thomas, E.L., Bell, J.D., Swann Jonathan, Costabile, A., Russell-Jones, D., Umpleby, A.M. and Robertson, M.D. 2014. Efficacy of increased resistant starch consumption in human type 2 diabetes. Endocrine Connections. 3 (2), pp. 75-84. https://doi.org/10.1530/EC-14-0036

Capacity planning of a perinatal network with generalised loss network model with overflow
Asaduzzaman, M. and Chaussalet, T.J. 2014. Capacity planning of a perinatal network with generalised loss network model with overflow. European Journal of Operational Research. 232 (1), pp. 178-185. https://doi.org/10.1016/j.ejor.2013.06.037

The short-chain fatty acid acetate reduces appetite via a central homeostatic mechanism
Frost, G.S., Sleeth Michelle, L., Sahuri-Arisoylu, Meliz, Lizarbe, Blanca, Cerdan, Sebastian, Brody, Leigh, Anastasovska, J., Ghourab, Samar, Hankir, M., Zhang Shuai, Carling, David, Swann, Jonathan, Gibson, G.R., Viardot, A., Morrison, Douglas, Thomas, E.L. and Bell, J.D. 2014. The short-chain fatty acid acetate reduces appetite via a central homeostatic mechanism. Nature Communications. 5 3611. https://doi.org/10.1038/ncomms4611

Adiposity and hepatic lipid in healthy full-term, breastfed, and formula-fed human infants: a prospective short-term longitudinal cohort study
Gale, C., Thomas, E.L., Jeffries, Suzan, Durighel, G., Logan, Karen M., Parkinson, J.R.C., Uthaya, S.N., Santhakumaran, S., Bell, J.D. and Modi, N. 2014. Adiposity and hepatic lipid in healthy full-term, breastfed, and formula-fed human infants: a prospective short-term longitudinal cohort study. American Journal of Clinical Nutition. 99 (5), pp. 1034-1040. https://doi.org/10.3945/ajcn.113.080200

Obese patients after gastric bypass surgery have lower brain-hedonic responses to food than after gastric banding
Scholtz, S., Miras, A.D., Chhina, N., Prechtl, C.G., Sleeth Michelle, L., Daud Norlida, M., Ismail Nurhafzan, Durighel, G., Ahmed, A.R., Olbers, T., Vincent, R.P., Alaghband-Zadeh, J., Ghatei, M.A., Waldman, A.D., Frost, G.S., Bell, J.D., le Roux, C.W. and Goldstone, A.P. 2014. Obese patients after gastric bypass surgery have lower brain-hedonic responses to food than after gastric banding. Gut. 63 (6), pp. 891-902. https://doi.org/10.1136/gutjnl-2013-305008

Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: rationale and design of the epidemiological studies within the IMI DIRECT Consortium
Koivula, R.W., Heggie, A., Barnett, A., Cederberg, H., Hansen, T.H., Koopman, A.D., Ridderstråle, M., Rutters, F., Vestergaard, H., Gupta, R., Herrgård, S., Heymans, M.W., Perry, M.H., Rauh, S., Siloaho, M., Teare, H.J.A., Thorand, B., Bell, J.D., Brunak, S., Frost, G.S., Jablonka, B., Mari, A., McDonald, T.J., Dekker, J.M., Hansen, T., Hattersley, A., Laakso, M., Pedersen, O., Koivisto, V., Ruetten, H., Walker, M., Pearson, E. and Franks, P.W. 2014. Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: rationale and design of the epidemiological studies within the IMI DIRECT Consortium. Diabetologia. 57 (6), pp. 1132-1142. https://doi.org/10.1007/s00125-014-3216-x

Ghrelin mimics fasting to enhance human hedonic, orbitofrontal cortex, and hippocampal responses to food
Goldstone, A.P., Prechtl, C.G., Scholtz, S., Miras, A.D., Chhina, N., Durighel, G., Deliran, S.S., Beckmann, C., Ghatei, M.A., Ashby, D.R., Waldman, A.D., Gaylinn, B.D., Thorner, M.O., Frost, G.S., Bloom, S.R. and Bell, J.D. 2014. Ghrelin mimics fasting to enhance human hedonic, orbitofrontal cortex, and hippocampal responses to food. American Journal of Clinical Nutition. 99 (6), pp. 1319-1330. https://doi.org/10.3945/ajcn.113.075291

The impact of oligofructose on stimulation of gut hormones, appetite regulation and adiposity
Daud Norlida, M., Ismail Nurhafzan, Thomas, E.L., Fitzpatrick, J., Swann Jonathan, Costabile, A., Pedersen, C., Frost, G.S., Bell, J.D., Childs, C.E. and Goldstone, A.P. 2014. The impact of oligofructose on stimulation of gut hormones, appetite regulation and adiposity. Obesity (Silver Spring). 22 (6), pp. 1430-1438. https://doi.org/10.1002/oby.20754

Towards an evidence-based decision making healthcare system management: modelling patient pathways to improve clinical outcomes
Adeyemi, S., Demir, E. and Chaussalet, T.J. 2013. Towards an evidence-based decision making healthcare system management: modelling patient pathways to improve clinical outcomes. Decision Support Systems. 55 (1), pp. 117-125. https://doi.org/10.1016/j.dss.2012.12.039

MAPPED study design: A 6month randomised controlled study to evaluate the effect of dutasteride on prostate cancer volume using magnetic resonance imaging
Robertson, N.L., Moore, C.M., Ambler, G., Bott, S.R.J., Freeman, A., Gambarota, G., Jameson, C., Mitra, A.V., Whitcher, B., Winkler, M., Kirkham, A., Allen, C. and Emberton, M. 2013. MAPPED study design: A 6month randomised controlled study to evaluate the effect of dutasteride on prostate cancer volume using magnetic resonance imaging. Contemporary Clinical Trials. 34 (1), pp. 80-89. https://doi.org/10.1016/j.cct.2012.10.003

Brain microstructure reveals early abnormalities more than two years prior to clinical progression from mild cognitive impairment to Alzheimer's disease
Douaud, G., Menke, R.A.L., Gass, A., Monsch, A.U., Rao, A., Whitcher, B., Zamboni, G., Matthews, P.M., Sollberger, M. and Smith, S. 2013. Brain microstructure reveals early abnormalities more than two years prior to clinical progression from mild cognitive impairment to Alzheimer's disease. Journal of Neuroscience. 33 (5), pp. 2147-2155. https://doi.org/10.1523/jneurosci.4437-12.2013

Preferential lectin binding of cancer cells upon sialic acid treatment under nutrient deprivation.
Badr, H.A., Elsayed, A.I., Ahmed, H., Dwek, M.V., Li, C.Z. and Djansugurova, L.B. 2013. Preferential lectin binding of cancer cells upon sialic acid treatment under nutrient deprivation. Applied Biochemistry and Biotechnology. 171, pp. 963-974. https://doi.org/10.1007/s12010-013-0409-6

Healthcare planning and its potential role increasing operational efficiency in the health sector: a viewpoint
Virtue, A., Chaussalet, T.J. and Kelly, J. 2013. Healthcare planning and its potential role increasing operational efficiency in the health sector: a viewpoint. Journal of Enterprise Information Management. 26 (1/2), pp. 8-20. https://doi.org/10.1108/17410391311289523

Early nutritional determinants of intrahepatocellular lipid deposition in preterm infants at term age
Vasu, V., Thomas, E.L., Durighel, G., Hyde, M.J., Bell, J.D. and Modi, N. 2013. Early nutritional determinants of intrahepatocellular lipid deposition in preterm infants at term age. International Journal of Obesity. 37 (4), pp. 500-504. https://doi.org/10.1038/ijo.2012.213

Metabolic syndrome, overweight and fatty liver
Thomas, E.L., Fitzpatrick, J., Frost, G.S. and Bell, J.D. 2013. Metabolic syndrome, overweight and fatty liver. in: Berdanier, C.D., Dwyer, J.T. and Heber, D. (ed.) Handbook of nutrition and food, 3rd edition Boca Raton CRC Press. pp. 763-768

Conjugation of quantum dots on carbon nanotubes for medical diagnosis and treatment
Madani, S.Y., Shabani, F., Dwek, M. and Seifalian, A.M. 2013. Conjugation of quantum dots on carbon nanotubes for medical diagnosis and treatment. International Journal of Nanomedicine. 8 (1), pp. 941-950. https://doi.org/10.2147/IJN.S36416

Mutations in the GABRB1 gene promote alcohol consumption through increased tonic inhibition
Anstee, Q.M., Knapp, S., Maguire, E.P., Hosie, A.M., Thomas, P., Mortensen, M., Bhome, R., Martinez, A., Walker, S.E., Dixon, C.I., Ruparelia, K., Montagnese, S., Kuo, Y.T., Herlihy, A.H., Bell, J.D., Robinson, I., Guerrini, I., McQuillin, A., Fisher, E.M.C., Ungless, M.A., Gurling, H.M.D., Morgan, M.Y., Brown, S.D.M., Stephens, D.N., Belelli, D., Lambert, J.J., Smart, T.G. and Thomas, H.C. 2013. Mutations in the GABRB1 gene promote alcohol consumption through increased tonic inhibition. Nature Communications. 4, p. 2816. https://doi.org/10.1038/ncomms3816

A targeted glycoproteomic approach identifies cadherin-5 as a novel biomarker of metastatic breast cancer
Fry, S., Sinclair, J., Timms, J.F., Leathem, A. and Dwek, M. 2013. A targeted glycoproteomic approach identifies cadherin-5 as a novel biomarker of metastatic breast cancer. Cancer Letters. 328 (2), pp. 335-344. https://doi.org/10.1016/j.canlet.2012.10.011

Overcoming the barriers: a qualitative study of simulation adoption in the NHS
Brailsford, S.C., Bolt, T.B., Bucci, G., Chaussalet, T.J., Connell, N.A.D., Harper, P.R., Klein, J.H., Pitt, M. and Taylor, M. 2013. Overcoming the barriers: a qualitative study of simulation adoption in the NHS. Journal of the Operational Research Society. 64 (2), pp. 157-168. https://doi.org/10.1057/jors.2011.130

The DietCompLyf study: a prospective cohort study of breast cancer survival and phytoestrogen consumption
Swann, R., Perkins, K.A., Velentzis, L.S., Ciria, C., Dutton, S., Mulligan, A.A., Woodside, J., Cantwell, M.M., Leathem, A., Robertson, C.E. and Dwek, M. 2013. The DietCompLyf study: a prospective cohort study of breast cancer survival and phytoestrogen consumption. Maturitas. 75 (3), pp. 232-240. https://doi.org/10.1016/j.maturitas.2013.03.018

Whole body fat: content and distribution
Thomas, E.L., Fitzpatrick, J., Malik, S.J., Taylor-Robinson, S.D. and Bell, J.D. 2013. Whole body fat: content and distribution. Progress in Nuclear Magnetic Resonance Spectroscopy. 73, pp. 56-80. https://doi.org/10.1016/j.pnmrs.2013.04.001

A history of previous gestational diabetes mellitus is associated with adverse changes in insulin secretion and VLDL metabolism independently of increased intrahepatocellular lipid
Forbes, S., Godsland, I.F., Taylor-Robinson, S.D., Bell, J.D., Thomas, E.L., Patel, N., Hamilton, G., Parker, K.H., Marshall, I., Gray, C.D., Bedford, D.C., Caslake, M., Walker, B.R. and Johnston, D.G. 2013. A history of previous gestational diabetes mellitus is associated with adverse changes in insulin secretion and VLDL metabolism independently of increased intrahepatocellular lipid. Diabetologia. 56 (9), pp. 2021-2033. https://doi.org/10.1007/s00125-013-2956-3

Endocannabinoids in neuroendopsychology: multiphasic control of mitochondrial function
Nunn, A.V.W., Guy, G.W. and Bell, J.D. 2012. Endocannabinoids in neuroendopsychology: multiphasic control of mitochondrial function. Philosophical Transactions of the Royal Society B: Biological Sciences. 367 (1607), pp. 3342-3352. https://doi.org/10.1098/rstb.2011.0393

Adiposity in children and adolescents: correlates and clinical consequences of fat stored in specific body depots
Katzmarzyk, P.T., Shen, W., Baxter-Jones, A., Bell, J.D., Butte, N.F., Demerath, E.W., Gilsanz, V., Goran, M.I., Hirschler, V., Hu, H.H., Maffeis, C., Malina, R.M., Müller, M.J., Pietrobelli, A. and Wells, J.C.K. 2012. Adiposity in children and adolescents: correlates and clinical consequences of fat stored in specific body depots. Pediatric Obesity. 7 (5), pp. e42-e61. https://doi.org/10.1111/j.2047-6310.2012.00073.x

Effect of lactobacillus acidophilus NCDC 13 supplementation on the progression of obesity in diet-induced obese mice
Arora, T., Anastasovska, J., Gibson, G.R., Tuohy, K., Kumar Sharma, R., Bell, J.D. and Frost, G.S. 2012. Effect of lactobacillus acidophilus NCDC 13 supplementation on the progression of obesity in diet-induced obese mice. British Journal of Nutrition. 108 (8), pp. 1382-1389. https://doi.org/10.1017/S0007114511006957

The DietCompLyf study: a prospective longitudinal study of breast cancer survival
Swann, R., Perkins, A., Velentzis, L.S., Mulligan, A.M., Woodside, J., Cantwell, M.M., Dutton, S., Leathem, A., Robertson, C.E. and Dwek, M. 2012. The DietCompLyf study: a prospective longitudinal study of breast cancer survival. European Journal of Cancer. 48 (5), p. S216. https://doi.org/10.1016/S0959-8049(12)71525-3

DietCompLyf study: a multi-centre UK study on breast cancer. What are the dietary and lifestyle changes following diagnosis?
Perkins, A., Swann, R., Woodside, J., Robertson, C.E., Dutton, S., Mulligan, A.M., Velentzis, L.S., Keshtgar, M.R., Leathem, A. and Dwek, M. 2012. DietCompLyf study: a multi-centre UK study on breast cancer. What are the dietary and lifestyle changes following diagnosis? European Journal of Cancer. 48 (5), p. S282. https://doi.org/10.1016/S0959-8049(12)71766-5

Identification of metastasis-associated glycoproteins in colorectal cancer
Peiris, D., Markiv, A., Curley, G.P. and Dwek, M. 2012. Identification of metastasis-associated glycoproteins in colorectal cancer. European Journal of Cancer. 48 (5), pp. S39-S40. https://doi.org/10.1016/S0959-8049(12)70863-8

The effect of preterm birth on adiposity and metabolic pathways and the implications for later life
Thomas, E.L., Al Saud, N.B., Durighel, G., Frost, G.S. and Bell, J.D. 2012. The effect of preterm birth on adiposity and metabolic pathways and the implications for later life. Clinical Lipidology. 7 (3), pp. 275-288. https://doi.org/10.2217/clp.12.32

Elemental imaging of MRI contrast agents: benchmarking of LA-ICP-MS to MRI
Pugh, J.A.T., Cox, A.G., McLeod, C.W., Bunch, J., Writer, M.J., Hart, S.L., Bienemann, A., White, E. and Bell, J.D. 2012. Elemental imaging of MRI contrast agents: benchmarking of LA-ICP-MS to MRI. Analytical and bioanalytical chemistry. 403 (6), pp. 1641-1649. https://doi.org/10.1007/s00216-012-5973-z

19p13.1 is a triple negative-specific breast cancer susceptibility locus
Stevens, K.N., Fredericksen, Z., Vachon, C., Wang, X., Margolin, S., Lindblom, A., Nevanlinna, H., Greco, D., Aittomaki, K., Blomqvist, C., Chang-Claude, J., Vrieling, A., Flesch-Janys, D., Sinn, H.P., Wang-Gohrke, S., Nickels, S., Brauch, H., Ko, Y.-D., Fischer, H.P., Schmutzler, R.K., Meindl, A., Bartram, C.R., Schott, S., Engel, C., Godwin, A.K., Weaver, J., Pathak, H.B., Sharma, P., Brenner, H., Muller, H., Arndt, V., Stegmaier, C., Miron, P., Yannoukakos, D., Stavropoulou, A., Fountzilas, G., Gogas, H.J., Swann, R., Dwek, M., Perkins, A., Milne, R.L., Benitez, J., Zamora, M.P., Ignacio Arias Perez, J., Bojesen, S.E., Nielsen, S.F., Nordestgaard, B.G., Flyger, H., Guenel, P., Truong, T., Menegaux, F., Cordina-Duverger, E., Burwinkel, B., Marme, F., Schneeweiss, A., Sohn, C., Sawyer, E., Tomlinson, I., Kerin, M.J., Peto, J., Johnson, N., Fletcher, O., Dos Santos Silva, I., Fasching, P.A., Beckmann, M.W., Hartmann, A., Ekici, A.B., Lophatananon, A., Muir, K., Puttawibul, P., Wiangnon, S., Schmidt, M.K., Broeks, A., Braaf, L.M., Rosenberg, E.H., Hopper, J.L., Apicella, C., Park, D.J., Southey, M.C., Swerdlow, A.J., Ashworth, A., Orr, N., Schoemaker, M.J., Anton-Culver, H., Ziogas, A., Bernstein, L., Clarke Dur, C., Shen, C.Y., Yu, J.C., Hsu, H.M., Hsiung, C.N., Hamann, U., Dünnebier, T., Rüdiger, T., Ulmer, H.U., Pharoah, P.D.P., Dunning, A.M., Humphreys, M.K., Wang, Q., Cox, A., Cross, S.S., Reed, M.W.R., Hall, P., Czene, K., Ambrosone, C.B., Ademuyiwa, F., Hwang, H., Eccles, D.M., Garcia-Closas, M., Figueroa, J.D., Sherman, M.E., Lissowska, J., Devilee, P., Seynaeve, C., Tollenaar, R.A.E.M., Hooning, M.J., Andrulis, I.L., Knight, J.A., Glendon, G., Mulligan, A.M., Winqvist, R., Pylkas, K., Jukkola-Vuorinen, A., Grip, M., John, E.M., Miron, A., Grenaker Alnaes, G., Kristensen, V., Borresen-Dale, A.L., Giles, G.G., Baglietto, L., McLean, C.A., Severi, G., Kose, M.L., Pankratz, V.S., Slager, S., Olson, J.E., Radice, P., Peterlongo, P., Manoukian, S., Barile, M., Lambrechts, D., Hatse, S., Dieudonne, A.S., Christiaens, M.R., Chenevix-Trench, G., Beesley, J., Chen, X., Mannermaa, A., Kosma, V.-M., Hartikainen, J.M., Soini, Y., Easton, D.F., Couch, F.J. and Borrensen-Dale, A.-L. 2012. 19p13.1 is a triple negative-specific breast cancer susceptibility locus. Cancer Research. 72 (7), pp. 1795-1803. https://doi.org/10.1158/0008-5472.CAN-11-3364

BEaST: brain extraction based on nonlocal segmentation technique.
Eskildsen, S.F., Coupé, P., Fonov, V., Manjón, J.V., Leung, K.K., Guizard, N., Wassef, S.N., Østergaard, L.R., Collins, D.L., Alzheimer's Disease Neuroimaging Initiative and Whitcher, B. 2012. BEaST: brain extraction based on nonlocal segmentation technique. NeuroImage. 59 (3), pp. 2362-2373. https://doi.org/10.1016/j.neuroimage.2011.09.012

Individual subject classification for Alzheimer's disease based on incremental learning using a spatial frequency representation of cortical thickness data.
Cho, Y., Seong, J.K., Jeong, Y., Shin, S.Y., Alzheimer's Disease Neuroimaging Initiative and Whitcher, B. 2012. Individual subject classification for Alzheimer's disease based on incremental learning using a spatial frequency representation of cortical thickness data. NeuroImage. 59 (3), pp. 2217-2230. https://doi.org/10.1016/j.neuroimage.2011.09.085

Detecting global and local hippocampal shape changes in Alzheimer's disease using statistical shape models.
Shen, K.K., Fripp, J., Mériaudeau, F., Chételat,G., Salvado, O., Bourgeat, P., Alzheimer's Disease Neuroimaging Initiative and Whitcher, B. 2012. Detecting global and local hippocampal shape changes in Alzheimer's disease using statistical shape models. NeuroImage. 59 (3), pp. 2155-2166. https://doi.org/10.1016/j.neuroimage.2011.10.014

Localized hippocampus measures are associated with Alzheimer pathology and cognition independent of total hippocampal volume.
Carmichael, O., Xie, J., Fletcher, E., Singh, B., DeCarli, C., Alzheimer's Disease Neuroimaging Initiative and Whitcher, B. 2012. Localized hippocampus measures are associated with Alzheimer pathology and cognition independent of total hippocampal volume. Neurobiology of Aging. 33 (6), pp. 1124.e31-1124.e41. https://doi.org/10.1016/j.neurobiolaging.2011.08.016

Imaging vascular function for early stage clinical trials using dynamic contrast-enhanced magnetic resonance imaging
Leach, M.O., Morgan, B., Tofts, P.S., Buckley, D.L., Huang, W., Horsfield, M.A., Chenevert, T.L., Collins, D.J., Jackson, A., Lomas, D., Whitcher, B., Clarke, L., Plummer, R., Judson, I., Jones, R., Alonzi, R., Brunner, T., Koh, D.M., Murphy, P., Waterton, J.C., Parker, G., Graves, M.J., Scheenen, T.W.J., Redpath, T.W., Orton, M., Karczmar, G., Huisman, H., Barentsz, J. and Padhani, A. 2012. Imaging vascular function for early stage clinical trials using dynamic contrast-enhanced magnetic resonance imaging. European Radiology. 22, pp. 1451-1464. https://doi.org/10.1007/s00330-012-2446-x

A Comparison of Gray Matter Density in Restless Legs Syndrome Patients and Matched Controls Using Voxel-Based Morphometry
Comley, R.A., Cervenka, S., Palhagen, S.E., Panagiotidis, G., Matthews, J.C., Lai, R.Y., Halldin, C., Farde, L., Nichols, T.E. and Whitcher, B. 2012. A Comparison of Gray Matter Density in Restless Legs Syndrome Patients and Matched Controls Using Voxel-Based Morphometry. Journal of Neuroimaging. 22 (1), pp. 28-32. https://doi.org/10.1111/j.1552-6569.2010.00536.x

Verbal working memory and functional large-scale networks in schizophrenia
Dauvermann, M.R., Moorhead, T.W., Watson, A.R., Duff, B., Romaniuk, L., Hall, J., Roberts, N., Lee, G.L., Hughes, Z.A., Brandon, N.J., Whitcher, B., Blackwood, D.H., McIntosh, A.M. and Lawrie, S.M. 2012. Verbal working memory and functional large-scale networks in schizophrenia. Psychiatry Research: Neuroimaging. 270, pp. 86-96. https://doi.org/10.1016/j.pscychresns.2017.10.004

Using CSF biomarkers to replicate genetic associations in Alzheimer's disease.
Schott, J.M., ADNI Investigators and Whitcher, B. 2012. Using CSF biomarkers to replicate genetic associations in Alzheimer's disease. Neurobiology of Aging. 33 (7), pp. 1486.e9-1486.e15. https://doi.org/10.1016/j.neurobiolaging.2011.02.008

Genetic variation in GOLM1 and prefrontal cortical volume in Alzheimer's disease
Inkster, B., Rao, A.W., Ridler, K., Filippini, N., Whitcher, B., Nichols, T.E., Wetten, S., Gibson, R.A., Borrie, M., Kertesz, A., Guzman, D.A., Loy-English, I., Williams, J., Saemann, P.G., Auer, D.P., Holsboer, F., Tozzi, F., Muglia, P., Merlo-Pich, E. and Matthews, P.M. 2012. Genetic variation in GOLM1 and prefrontal cortical volume in Alzheimer's disease. Neurobiology of Aging. https://doi.org/10.1016/j.neurobiolaging.2010.04.018

Differential effects of two fermentable carbohydrates on central appetite regulation and body composition
Arora, T., Loo, R.L., Anastasovska, J., Gibson, G.R., Tuohy, K., Kumar Sharma, R., Swann Jonathan, Deaville, E.R., Sleeth Michelle, L., Thomas, E.L., Holmes, E., Bell, J.D. and Frost, G.S. 2012. Differential effects of two fermentable carbohydrates on central appetite regulation and body composition. PLoS ONE. 7 (8) e43263. https://doi.org/10.1371/journal.pone.0043263

Improved Glycaemia correlates with liver fat reduction in obese, type 2 diabetes, patients given glucagon-like peptide-1 (GLP-1) receptor agonists
Cuthbertson, D.J., Irwin, A., Gardner, C.J., Daousi, C., Purewal, T, Furlong, N, Goenka, N, Thomas, E.L., Adams, V.L., Pushpakom, SP, Pirmohamed, M and Kemp, G.J. 2012. Improved Glycaemia correlates with liver fat reduction in obese, type 2 diabetes, patients given glucagon-like peptide-1 (GLP-1) receptor agonists. PLoS ONE. 7 (12) e50117. https://doi.org/10.1371/journal.pone.0050117

Forecasting long-term care demand under incomplete information: a grey modelling approach
Worrall, P. and Chaussalet, T.J. 2012. Forecasting long-term care demand under incomplete information: a grey modelling approach. in: 2012 25th International symposium on computer-based medical systems (CBMS), 20-22 June 2012, Rome, Italy IEEE .

Development of a hybrid grey-fuzzy methodology to forecast future demand for long-term care
Worrall, P. and Chaussalet, T.J. 2012. Development of a hybrid grey-fuzzy methodology to forecast future demand for long-term care. High Tech Human Touch: Proceedings of the 38th ORAHS conference. University of Twente, The Netherlands. 16-20 July 2012

Healthcare planning: the simulation perspective
Virtue, A., Chaussalet, T.J. and Kelly, J. 2012. Healthcare planning: the simulation perspective. Operational research society simulation workshop 2012 (SW12). Worcestershire, England 27th - 28th March 2012

Validation of dual energy x-ray absorptiometry measures of abdominal fat by comparison with magnetic resonance imaging in an Indian population
Taylor, A.E., Kuper, H., Varma, R.D., Wells, J.C.K., Bell, J.D., Radhakrishna, K.V., Kulkarni, B., Kinra, S., Timpson, N.J., Ebrahim, S., Smith, G.D. and Ben-Shlomo, Y. 2012. Validation of dual energy x-ray absorptiometry measures of abdominal fat by comparison with magnetic resonance imaging in an Indian population. PLoS ONE. 7 (12) e51042. https://doi.org/10.1371/journal.pone.0051042

Using data mining and simulation for health system understanding and capacity planning: an application to urgent care
Tadjer, M., Chaussalet, T.J., Fouladinajed, F. and Chahed, S. 2012. Using data mining and simulation for health system understanding and capacity planning: an application to urgent care. High Tech Human Touch: Proceedings of the 38th ORAHS conference. University of Twente, The Netherlands. 16-20 July 2012

Metabolic profiling of the rat liver after chronic ingestion of alpha-naphthylisothiocyanate using in vivo and ex vivo magnetic resonance spectroscopy
Solanky, B.S., Sanchez-Canon, G.J., Cobbold, J.F.L., Taylor-Robinson, S.D., Bell, J.D., Scudamore, C.L., Ross, E., Holder, J.C., So, P.W. and Cox, I.J. 2012. Metabolic profiling of the rat liver after chronic ingestion of alpha-naphthylisothiocyanate using in vivo and ex vivo magnetic resonance spectroscopy. Toxicological Sciences. 126 (2), pp. 306-316. https://doi.org/10.1093/toxsci/kfs019

A risk analysis method for assessing risks based on interval-valued fuzzy number
Rathi, M. and Chaussalet, T.J. 2012. A risk analysis method for assessing risks based on interval-valued fuzzy number. in: 2012 IEEE International conference on computational intelligence and computing research (ICCIC), 18-20 December 2012, Coimbatore, India IEEE .

Predicting hospital resource utilization: a fuzzy regression approach
Rathi, M. and Chaussalet, T.J. 2012. Predicting hospital resource utilization: a fuzzy regression approach. High Tech Human Touch: Proceedings of the 38th ORAHS conference. University of Twente, The Netherlands. 16-20 July 2012

The lectin Helix pomatia agglutinin recognises O-GlcNAc containing glycoproteins in human breast cancer
Rambaruth, N.D.S., Greenwell, P. and Dwek, M. 2012. The lectin Helix pomatia agglutinin recognises O-GlcNAc containing glycoproteins in human breast cancer. Glycobiology. 22 (6), pp. 839-848. https://doi.org/10.1093/glycob/cws051

Functionalization of single-walled carbon nanotubes and their binding to cancer cells.
Madani, S.Y., Tan, A., Dwek, M. and Seifalian, A.M. 2012. Functionalization of single-walled carbon nanotubes and their binding to cancer cells. International Journal of Nanomedicine. 2012 (7), pp. 905-914. https://doi.org/10.2147/ijn.s25035

Nonparametric smoothing of the impact of climate change for some selected diseases: a case study for Greater London
Islam, M., Chaussalet, T.J., Ozkan, N. and Demir, E. 2012. Nonparametric smoothing of the impact of climate change for some selected diseases: a case study for Greater London. High Tech Human Touch: Proceedings of the 38th ORAHS conference. University of Twente, The Netherlands. 16-20 July 2012

Increased energy expenditure in gastric bypass rats is not caused by activated brown adipose tissue
Hankir, M., Bueter, M., Gsell, W., Seyfried, F., Khalil, M., Smith, K.L., Bloom, S.R., Bell, J.D. and le Roux, C.W. 2012. Increased energy expenditure in gastric bypass rats is not caused by activated brown adipose tissue. Obesity Facts. 5 (3), pp. 349-358. https://doi.org/10.1159/000339742

Lectin array based strategies for identifying metastasis-associated changes in glycosylation
Fry, S., Afrough, B., Leathem, A. and Dwek, M. 2012. Lectin array based strategies for identifying metastasis-associated changes in glycosylation. Methods in Molecular Biology. 878, pp. 267-272. https://doi.org/10.1007/978-1-61779-854-2_18

2DE- based proteomics for the analysis of metastasis associated proteins
Dwek, M. and Peiris, D. 2012. 2DE- based proteomics for the analysis of metastasis associated proteins. Methods in Molecular Biology. 878, pp. 111-120. https://doi.org/10.1007/978-1-61779-854-2_7

Profiling hospitals based on emergency readmission: a multilevel transition modelling approach
Demir, E., Chaussalet, T.J., Adeyemi, S. and Toffa, S.E. 2012. Profiling hospitals based on emergency readmission: a multilevel transition modelling approach. Computer Methods and Programs in Biomedicine. 108 (2), pp. 487-499. https://doi.org/10.1016/j.cmpb.2011.03.003

A decision support tool for health service re-design
Demir, E., Chahed, S., Chaussalet, T.J., Toffa, S.E. and Fouladinajed, F. 2012. A decision support tool for health service re-design. Journal of Medical Systems. 36 (2), pp. 621-630. https://doi.org/10.1007/s10916-010-9526-8

How to predict high dependency cot demand in upcoming days
Dalton, S., Chahed, S. and Chaussalet, T.J. 2012. How to predict high dependency cot demand in upcoming days. ORAHS 2012 Conference: High Tech Human Touch. University of Twente Enschede, The Netherlands 15-20 July 2012

Relation between trunk fat volume and reduction of total lung capacity in obese men
Watson, R.A., Pride, N.B., Thomas, E.L., Ind, P.W. and Bell, J.D. 2012. Relation between trunk fat volume and reduction of total lung capacity in obese men. Journal of Applied Physiology. 112 (1), pp. 118-126. https://doi.org/10.1152/japplphysiol.00217.2011

The missing risk: MRI and MRS phenotyping of abdominal adiposity and ectopic fat
Thomas, E.L., Parkinson, J.R.C., Frost, G.S., Goldstone, A.P., Doré, C.J., McCarthy, J., Collins, A.L., Fitzpatrick, J., Durighel, G., Taylor-Robinson, S.D. and Bell, J.D. 2012. The missing risk: MRI and MRS phenotyping of abdominal adiposity and ectopic fat. Obesity. 20 (1), pp. 76-87. https://doi.org/10.1038/oby.2011.142

The effects of glutamate receptor agonists and antagonists on mouse hypothalamic and hippocampal neuronal activity shown through manganese enhanced MRI
Hankir, M., Parkinson, J.R.C., Bloom, S.R. and Bell, J.D. 2012. The effects of glutamate receptor agonists and antagonists on mouse hypothalamic and hippocampal neuronal activity shown through manganese enhanced MRI. NeuroImage. 59 (2), pp. 968-978. https://doi.org/10.1016/j.neuroimage.2011.08.063

Fermentable carbohydrate alters hypothalamic neuronal activity and protects against the obesogenic environment
Anastasovska, J., Arora, T., Sanchez-Canon, G.J., Parkinson, J.R.C., Touhy, K., Gibson, G.R., Nadkarni, N., So, P.W., Goldstone, A.P., Thomas, E.L., Hankir, M., Van Loo, J., Modi, N., Bell, J.D. and Frost, G.S. 2012. Fermentable carbohydrate alters hypothalamic neuronal activity and protects against the obesogenic environment. Obesity. 20 (5), pp. 1016-1023. https://doi.org/10.1038/oby.2012.6

A novel approach to determining the affinity of protein-carbohydrate interactions employing adherent cancer cells grown on a biosensor surface
Peiris, D., Markiv, A., Curley, G.P. and Dwek, M. 2012. A novel approach to determining the affinity of protein-carbohydrate interactions employing adherent cancer cells grown on a biosensor surface. Biosensors and Bioelectronics. 35 (1), pp. 160-166. https://doi.org/10.1016/j.bios.2012.02.037

Excess body fat in obese and normal weight subjects
Thomas, E.L., Frost, G.S., Taylor-Robinson, S.D. and Bell, J.D. 2012. Excess body fat in obese and normal weight subjects. Nutrition Research Reviews. 25 (1), pp. 150-161. https://doi.org/10.1017/S0954422412000054

Intrahepatic insulin exposure, intrahepatocellular lipid and regional body fat in non-alcoholic fatty liver disease
Mehta, S.R., Godsland, I.F., Thomas, E.L., Pavitt, D.V., Morin, S.H.X., Bell, J.D., Taylor-Robinson, S.D. and Johnston, D.G. 2012. Intrahepatic insulin exposure, intrahepatocellular lipid and regional body fat in non-alcoholic fatty liver disease. Journal of Clinical Endocrinology and Metabolism. 97 (6), pp. 2151-2159. https://doi.org/10.1210/jc.2011-2430

Hepatic steatosis, GH deficiency and the effects of GH replacement: a Liverpool magnetic resonance spectroscopy study
Gardner, C.J., Irwin, A., Daousi, C., McFarlane, I.A., Joseph, F., Bell, J.D., Thomas, E.L., Adams, V.L., Kemp, G.J. and Cuthbertson, D.J. 2012. Hepatic steatosis, GH deficiency and the effects of GH replacement: a Liverpool magnetic resonance spectroscopy study. European Journal of Endocrinology. 166, pp. 993-1002. https://doi.org/10.1530/EJE-12-0002

Gender differences in VLDL1 and VLDL2 triglyceride kinetics and fatty acid kinetics in obese postmenopausal women and obese men
Sarac, I., Backhouse, K., Shojaee-Moradie, F., Stolinski, M., Robertson, M.D., Bell, J.D., Thomas, E.L., Hovorka, R., Wright, J. and Umpleby, A.M. 2012. Gender differences in VLDL1 and VLDL2 triglyceride kinetics and fatty acid kinetics in obese postmenopausal women and obese men. Journal of Clinical Endocrinology and Metabolism. 97 (7), pp. 2475-2481. https://doi.org/10.1210/jc.2011-3248

Beyond the genome and proteome: targeting protein modifications in cancer
Markiv, A., Rambaruth, N.D.S. and Dwek, M. 2012. Beyond the genome and proteome: targeting protein modifications in cancer. Current Opinions in Pharmacology.. 12 (4), pp. 408-413. https://doi.org/10.1016/j.coph.2012.04.003

Fatty acid flux and oxidation are increased by rimonabant in obese women
Backhouse, K., Sarac, I., Shojaee-Moradie, F., Stolinski, M., Robertson, M.D., Frost, G.S., Bell, J.D., Thomas, E.L., Wright, J., Russell-Jones, D. and Umpleby, A.M. 2012. Fatty acid flux and oxidation are increased by rimonabant in obese women. Metabolism: Clinical and Experimental. 61 (9), pp. 1220-1223. https://doi.org/10.1016/j.metabol.2012.02.012

Polycystic ovary syndrome with hyperandrogenism is characterized by an increased risk of hepatic steatosis compared to nonhyperandrogenic PCOS phenotypes and healthy controls, independent of obesity and insulin resistance
Jones, H., Sprung, V.S., Pugh, C.J.A., Daousi, C., Irwin, A., Aziz, N., Adams, V.L., Thomas, E.L., Bell, J.D., Kemp, G.J. and Cuthbertson, D.J. 2012. Polycystic ovary syndrome with hyperandrogenism is characterized by an increased risk of hepatic steatosis compared to nonhyperandrogenic PCOS phenotypes and healthy controls, independent of obesity and insulin resistance. Journal of Clinical Endocrinology and Metabolism. 97 (10), pp. 3709-3716. https://doi.org/10.1210/jc.2012-1382

Association of serum anti-Tn IgM with breast cancer recurrence
Afrough, B., Fry, S., Lomax-Browne, H., Perkins, A., Leathem, A. and Dwek, M. 2011. Association of serum anti-Tn IgM with breast cancer recurrence. Immunology. 135 (Supp.1), p. 153. https://doi.org/10.1111/j.1365-2567.2011.03534.x

A physiological approach to assess the affinity of lectin carbohydrate interactions using cancer cells immobilised on a biosensor surface
Peiris, D., Markiv, A. and Dwek, M. 2011. A physiological approach to assess the affinity of lectin carbohydrate interactions using cancer cells immobilised on a biosensor surface. Glycobiology. 21 (11), p. 1523. https://doi.org/10.1093/glycob/cwr126

A low molecular weight folate receptor targeted contrast agent for magnetic resonance tumour imaging
Kalber, T., Kamaly, N., So, P.W., Pugh, J.A.T., Bunch, J., McLeod, C.W., Jorgensen, M.R., Miller, A.D. and Bell, J.D. 2011. A low molecular weight folate receptor targeted contrast agent for magnetic resonance tumour imaging. Molecular Imaging and Biology. 13 (4), pp. 653-662. https://doi.org/10.1007/s11307-010-0400-3

Synthesis and characterisation of a novel tubulin-directed DO3A–colchicine conjugate with potential theranostic features
Wardle, N.J., Kalber, T., Bell, J.D. and Bligh, S.W.A. 2011. Synthesis and characterisation of a novel tubulin-directed DO3A–colchicine conjugate with potential theranostic features. Bioorganic and Medicinal Chemistry Letters. 21 (11), pp. 3346-3348. https://doi.org/10.1016/j.bmcl.2011.04.014

Identification, cloning and characterization of two N-acetylgalactosamine binding lectins from the albumen gland of Helix pomatia
Markiv, A., Peiris, D., Curley, G.P., Odell, M. and Dwek, M. 2011. Identification, cloning and characterization of two N-acetylgalactosamine binding lectins from the albumen gland of Helix pomatia. Journal of Biological Chemistry. 286 (23), pp. 20260-20266. https://doi.org/10.1074/jbc.M110.184515

Capturing the readmission process: focus on time window
Demir, E. and Chaussalet, T.J. 2011. Capturing the readmission process: focus on time window. Journal of Applied Statistics. 38 (5), pp. 951-960. https://doi.org/10.1080/02664761003692415

An overflow loss network model for capacity planning of a perinatal network
Asaduzzaman, M. and Chaussalet, T.J. 2011. An overflow loss network model for capacity planning of a perinatal network. Journal of the Royal Statistical Society: Series A. 174 (2), pp. 403-417. https://doi.org/10.1111/j.1467-985X.2010.00669.x

Peptide YY3-36 and pancreatic polypeptide differentially regulate hypothalamic neuronal activity in mice in vivo as measured by manganese-enhanced magnetic resonance imaging
Hankir, M., Parkinson, J.R.C., Minnion, J.S., Addison, M.L., Bloom, S.R. and Bell, J.D. 2011. Peptide YY3-36 and pancreatic polypeptide differentially regulate hypothalamic neuronal activity in mice in vivo as measured by manganese-enhanced magnetic resonance imaging. Journal of Neuroendocrinology. 23 (4), pp. 371-380. https://doi.org/10.1111/j.1365-2826.2011.02111.x

Novel multifunctional nanoparticle mediates siRNA tumour delivery, visualisation and therapeutic tumour reduction in vivo
Kenny, G., Kamaly, N., Kalber, T., Brody Leigh, Sahuri-Arisoylu Meliz, Shamsaei, E., Miller, A.D. and Bell, J.D. 2011. Novel multifunctional nanoparticle mediates siRNA tumour delivery, visualisation and therapeutic tumour reduction in vivo. Journal of Controlled Release. 149 (2), pp. 111-116. https://doi.org/10.1016/j.jconrel.2010.09.020

DCE-MRI biomarkers of tumour heterogeneity predict CRC liver metastasis shrinkage following bevacizumab and FOLFOX-6
O'Connor, J.P.B., Rose, C.J., Jackson, A., Watson, Y., Cheung, S., Maders, F., Whitcher, B.J., Roberts, C., Buonaccorsi, G.A., Thompson, G., Clamp, A.R., Jayson, G.C. and Parker, G.J.M. 2011. DCE-MRI biomarkers of tumour heterogeneity predict CRC liver metastasis shrinkage following bevacizumab and FOLFOX-6. British Journal of Cancer. 105, pp. 139-145. https://doi.org/10.1038/bjc.2011.191

Validation and pilot application of [ 18F]FDG-PET in evaluation of a metabolic therapy for Alzheimer's disease
Tzimopoulou, S., Cunningham, V.J., Nichols, T.E., Searle, G., Bird, N.P., Mistry, P., Dixon, I.J., Hallett, W.A., Whitcher, B., Brown, A.P., Zvartau-Hind, M., Lotay, N., Lai, R.Y.K., Castiglia, M., Jeter, B., Matthews, J.C., Chen, K., Bandy, D., Reiman, E.M., Gold, M., Rabiner, E.A. and Matthews, P.M. 2011. Validation and pilot application of [ 18F]FDG-PET in evaluation of a metabolic therapy for Alzheimer's disease. Advances in Alzheimer's Disease. 2, pp. 627-642. https://doi.org/10.3233/978-1-60750-793-2-627

Image analysis and statistical inference in neuroimaging with R
Tabelow, K., Clayden, J.D., Lafaye de Micheaux, P., Polzehl, J., Schmid, V.J. and Whitcher, B. 2011. Image analysis and statistical inference in neuroimaging with R. NeuroImage. 55 (4), pp. 1686-1693. https://doi.org/10.1016/j.neuroimage.2011.01.013

DTI measures in crossing-fibre areas: Increased diffusion anisotropy reveals early white matter alteration in MCI and mild Alzheimer's disease
Douaud, G., Jbabdi, S., Behrens, T.E.J., Menke, R.A., Gass, A., Monsch, A.U., Rao, A., Whitcher, B., Kindlmann, G., Matthews, P.M. and Smith, S. 2011. DTI measures in crossing-fibre areas: Increased diffusion anisotropy reveals early white matter alteration in MCI and mild Alzheimer's disease. NeuroImage. 55 (3), pp. 880-890. https://doi.org/10.1016/j.neuroimage.2010.12.008

Quantitative analysis of dynamic contrast-enhanced and diffusion-weighted magnetic resonance imaging for oncology in R
Whitcher, B. and Schmid, V.J. 2011. Quantitative analysis of dynamic contrast-enhanced and diffusion-weighted magnetic resonance imaging for oncology in R. Journal of Statistical Software. 44 (5), pp. 1-29. https://doi.org/10.18637/jss.v044.i05

Special volume on Magnetic Resonance Imaging in R
Tabelow, K. and Whitcher, B. 2011. Special volume on Magnetic Resonance Imaging in R. Journal of Statistical Software. 44 (1), pp. 1-6. https://doi.org/10.18637/jss.v044.i01

Working with the DICOM and NIfTI data standards in R
Whitcher, B., Schmid, V.J. and Thornton, A. 2011. Working with the DICOM and NIfTI data standards in R. Journal of Statistical Software. 44 (6), pp. 1-29. Advanced online publication. https://doi.org/10.18637/jss.v044.i06

Spatial patterns of brain amyloid-beta burden and atrophy rate associations in mild cognitive impairment.
Tosun, D., Schuff, N., Mathis, C.A., Jagust, W., Weiner, M.W., Alzheimer's Disease NeuroImaging Initiative and Whitcher, B. 2011. Spatial patterns of brain amyloid-beta burden and atrophy rate associations in mild cognitive impairment. Brain. 134 (4), p. 1077–1088. https://doi.org/10.1093/brain/awr044

Mild cognitive impairment: baseline and longitudinal structural MR imaging measures improve predictive prognosis.
McEvoy, L.K., Holland, D., Hagler, D.J., Fennema-Notestine, C., Brewer, J.B., Dale, A.M., Alzheimer's Disease Neuroimaging Initiative and Whitcher, B. 2011. Mild cognitive impairment: baseline and longitudinal structural MR imaging measures improve predictive prognosis. Radiology. 259 (3), pp. 834-843. https://doi.org/10.1148/radiol.11101975

Fine mapping of genetic variants in BIN1, CLU, CR1 and PICALM for association with cerebrospinal fluid biomarkers for Alzheimer's disease.
Kauwe, J.S., Cruchaga, C., Karch, C.M., Sadle, B., Lee, M., Mayo, K., Latu, W., Su'a, M., Fagan, A.M., Holtzman, D.M., Morris, J.C., Alzheimer's Disease Neuroimaging Initiative, Goate, A.M. and Whitcher, B. 2011. Fine mapping of genetic variants in BIN1, CLU, CR1 and PICALM for association with cerebrospinal fluid biomarkers for Alzheimer's disease. PLoS ONE. 6 (2) e15918. https://doi.org/10.1371/journal.pone.0015918

Towards an optimal purchasing policy for nursing home placements in long-term care
Worrall, P. and Chaussalet, T.J. 2011. Towards an optimal purchasing policy for nursing home placements in long-term care. in: Operational Research Information National Health Policy: proceedings of the 37th ORAHS conference School of Mathematics, Cardiff University.

Development of a web-based system using the model view controller paradigm to facilitate regional long-term care planning
Worrall, P. and Chaussalet, T.J. 2011. Development of a web-based system using the model view controller paradigm to facilitate regional long-term care planning. in: Olive, M. and Solomonides, T. (ed.) Proceedings of CMBS: the 24th International Symposium on Computer-Based Medical Systems, June 27th – 30th, 2011, Bristol, United Kingdom IEEE .

A case study using simplified discrete-event simulation models as a tool to reconfigure health care services
Virtue, A., Chaussalet, T.J. and Kelly, J. 2011. A case study using simplified discrete-event simulation models as a tool to reconfigure health care services. in: Operational Research Information National Health Policy: proceedings of the 37th ORAHS conference School of Mathematics, Cardiff University.

Using simplified discrete-event simulation models for real world health care applications
Virtue, A., Chaussalet, T.J. and Kelly, J. 2011. Using simplified discrete-event simulation models for real world health care applications. in: Jain, S., Creasey, R.R., Himmelspach, J., White, K.P. and Fu, M. (ed.) Proceedings of the 2011 Winter Simulation Conference WSC.

Aberrant adiposity and ectopic lipid deposition characterize the adult phenotype of the preterm infant
Thomas, E.L., Parkinson, J.R.C., Hyde, M.J., Yap, I.K.S., Holmes, E., Doré, C.J., Bell, J.D. and Modi, N. 2011. Aberrant adiposity and ectopic lipid deposition characterize the adult phenotype of the preterm infant. Paediatric Research. 70 (5), pp. 507-512. https://doi.org/10.1203/PDR.0b013e31822d7860

Pragmatic study of orlistat 60 mg on abdominal obesity
Thomas, E.L., Makwana, A., Newbould, R., Rao, A.W., Gambarota, G., Frost, G.S., Delafont, B., Mishra, R.G., Matthews, P.M., Berk, E.S., Schwartz, S.M., Bell, J.D. and Beaver, J.D. 2011. Pragmatic study of orlistat 60 mg on abdominal obesity. European Journal of Clinical Nutrition. 65, pp. 1256-1262. https://doi.org/10.1038/ejcn.2011.108

Towards a full implementation of collaborative care plan. OR Informing National Health Policy
Tadjer, M., Chaussalet, T.J., Fouladinejad, F., Chahed, S., Saiyed, S., Redzanovic, S. and Fouladinajed, F. 2011. Towards a full implementation of collaborative care plan. OR Informing National Health Policy. in: Operational Research Information National Health Policy: proceedings of the 37th ORAHS conference School of Mathematics, Cardiff University.

Abstract B76 - An overview of the DietCompLyf study - a multicentre UK study to evaluate the role of diet, lifestyle and complementary medicine use on breast cancer recurrence
Swann, R., Perkins, A., Dahya, P., Woodside, J., Dutton, S., Robertson, C.E., Velentzis, L.S., Leathem, A. and Dwek, M. 2011. Abstract B76 - An overview of the DietCompLyf study - a multicentre UK study to evaluate the role of diet, lifestyle and complementary medicine use on breast cancer recurrence. National Cancer Research Institute (NCRI) Cancer Conference 2011. BT Convention Centre, Liverpool, UK 06 - 09 Nov 2011

Targeting of anionic membrane species by lanthanide(III) complexes: towards improved MRI contrast agents for apoptosis
Surman, A.J., Kenny, G., Krishna Kumar, D., Bell, J.D., Casey, D.R. and Vilar, R. 2011. Targeting of anionic membrane species by lanthanide(III) complexes: towards improved MRI contrast agents for apoptosis. Chemical Communications. 47, pp. 10245-10247. https://doi.org/10.1039/C1CC13284A

Data warehousing based architecture for the reporting of the NHS primary care prescribing
Redzanovic, S., Chountas, P., Chaussalet, T.J., Fouladinejad, F., Tadjer, M. and Fouladinajed, F. 2011. Data warehousing based architecture for the reporting of the NHS primary care prescribing. in: Olive, M. and Solomonides, T. (ed.) Proceedings of CMBS: the 24th International Symposium on Computer-Based Medical Systems, June 27th – 30th, 2011, Bristol, United Kingdom IEEE .

The influence of maternal body mass index on infant adiposity and hepatic lipid content
Modi, N., Murgasova, D., Ruager-Martin, R., Thomas, E.L., Hyde, M.J., Gale, C., Santhakumaran, S., Doré, C.J., Alavi, Afshin and Bell, J.D. 2011. The influence of maternal body mass index on infant adiposity and hepatic lipid content. Paediatric Research. 70 (3), pp. 287-291. https://doi.org/10.1203/PDR.0b013e318225f9b1

Separation and characterization of different isoform populations of PSA in seminal fluid
Lines, A., Clarke, O., Dwek, M., Packer, S. and Edwards, R. 2011. Separation and characterization of different isoform populations of PSA in seminal fluid. American Association for Clinical Chemists Meeting. Atlanta, Georgia 15 - 19 Jul 2011

Synthesis and characterization of a theranostic vascular disrupting agent for in vivo MR imaging
Kalber, T., Kamaly, N., Higham, S.A., Pugh, J.A.T., Bunch, J., McLeod, C.W., Miller, A.D. and Bell, J.D. 2011. Synthesis and characterization of a theranostic vascular disrupting agent for in vivo MR imaging. Bioconjugate Chemistry. 22 (5), pp. 879-886. https://doi.org/10.1021/bc100329t

Exploring the effect of temperature variations on unplanned asthma admissions
Islam, M.S., Chaussalet, T.J., Balta-Ozkan, N. and Demir, E. 2011. Exploring the effect of temperature variations on unplanned asthma admissions. in: Operational Research Information National Health Policy: proceedings of the 37th ORAHS conference School of Mathematics, Cardiff University. pp. 74-88

The impact of temperature disparity on emergency readmissions and patient flows
Islam, M.S., Chaussalet, T.J., Balta-Ozkan, N., Chahed, S., Demir, E. and Sarran, C. 2011. The impact of temperature disparity on emergency readmissions and patient flows. in: Olive, M. and Solomonides, T. (ed.) Proceedings of CMBS: the 24th International Symposium on Computer-Based Medical Systems, June 27th – 30th, 2011, Bristol, United Kingdom IEEE .

Abstract LB14 - Lectin microarray profilling of metastatic breast cancers
Fry, S., Afrough, B., Lomax-Browne, H., Timms, J.F., Velentzis, L.S. and Dwek, M. 2011. Abstract LB14 - Lectin microarray profilling of metastatic breast cancers. National Cancer Research Institute (NCRI) Cancer Conference 2011. BT Convention Centre, Liverpool, UK 06 - 09 Nov 2011

Modelling high dependency care in the local neonatal unit
Dalton, S. and Chaussalet, T.J. 2011. Modelling high dependency care in the local neonatal unit. in: Operational Research Information National Health Policy: proceedings of the 37th ORAHS conference Cardiff School of Mathematics, Cardiff University.

Nonproportional random effects modelling of a neonatal unit operational patient pathways
Adeyemi, S., Chaussalet, T.J. and Demir, E. 2011. Nonproportional random effects modelling of a neonatal unit operational patient pathways. Statistical Methods and Applications. 20 (4), pp. 507-518. https://doi.org/10.1007/s10260-011-0174-z

A pyrophosphate-responsive gadolinium(III) MRI contrast agent
Surman, A.J., Bonnet, C.S., Lowe, M.P., Kenny, G., Bell, J.D., Tóth, É. and Vilar, R. 2011. A pyrophosphate-responsive gadolinium(III) MRI contrast agent. Chemistry: A European Journal. 17 (1), pp. 223-230. https://doi.org/10.1002/chem.201001397

Measuring and modelling occupancy time in NHS continuing healthcare
Chahed, S., Demir, E., Chaussalet, T.J., Millard, P.H. and Toffa, S.E. 2011. Measuring and modelling occupancy time in NHS continuing healthcare. BMC Health Services Research. 11 (155), p. 1. https://doi.org/10.1186/1472-6963-11-155

Editorial: IMA Health 2010
Vasilakis, C., Chaussalet, T.J. and Baker, R.D. 2011. Editorial: IMA Health 2010. Health Care Management Science. 14 (3), pp. 213-214. https://doi.org/10.1007/s10729-011-9174-7

Cell surface glycan-lectin interactions in tumor metastasis
Rambaruth, N.D.S. and Dwek, M. 2011. Cell surface glycan-lectin interactions in tumor metastasis. Acta Histochemica. 113 (6), pp. 591-600. https://doi.org/10.1016/j.acthis.2011.03.001

Manganese enhancement in non-CNS organs
Lee, L.W., So, P.W., Price, A.N., Parkinson, J.R.C., Larkman, D.J., Halliday, J., Poucher, S.M., Pugh, J.A.T., Cox, A.G., McLeod, C.W. and Bell, J.D. 2010. Manganese enhancement in non-CNS organs. NMR in Biomedicine. 23 (8), pp. 931-938. https://doi.org/10.1002/nbm.1513

Endocannabinoids, FOXO and the metabolic syndrome: redox, function and tipping point – the view from two systems
Nunn, A.V.W., Guy, G.W. and Bell, J.D. 2010. Endocannabinoids, FOXO and the metabolic syndrome: redox, function and tipping point – the view from two systems. Immunobiology. 215 (8), pp. 617-628. https://doi.org/10.1016/j.imbio.2009.03.005

Imaging of gadolinium spatial distribution in tumor tissue by laser ablation inductively coupled plasma mass spectrometry
Kamaly, N., Pugh, J.A.T., Kalber, T., Bunch, J., Miller, A.D., McLeod, C.W. and Bell, J.D. 2010. Imaging of gadolinium spatial distribution in tumor tissue by laser ablation inductively coupled plasma mass spectrometry. Molecular Imaging and Biology. 12 (4), pp. 361-366. https://doi.org/10.1007/s11307-009-0282-4

A loss network model with overflow for capacity planning of a neonatal unit
Asaduzzaman, M., Chaussalet, T.J. and Robertson, N.J. 2010. A loss network model with overflow for capacity planning of a neonatal unit. Annals of Operations Research. 178 (1), pp. 67-76. https://doi.org/10.1007/s10479-009-0548-x

Peripherally injected cholecystokinin-induced neuronal activation is modified by dietary composition in mice
Zeeni, N., Nadkarni, N., Bell, J.D., Even, P.C., Fromentin, G., Tome, D. and Darcel, N. 2010. Peripherally injected cholecystokinin-induced neuronal activation is modified by dietary composition in mice. NeuroImage. 50 (4), pp. 1560-1565. https://doi.org/10.1016/j.neuroimage.2010.01.065

The combined effects on neuronal activation and blood–brain barrier permeability of time and n-3 polyunsaturated fatty acids in mice, as measured in vivo using MEMRI
Kuo, Y.T., So, P.W., Parkinson, J.R.C., Yu, W.S., Hankir, M., Herlihy, A.H., Goldstone, A.P., Frost, G.S., Wasserfall, C. and Bell, J.D. 2010. The combined effects on neuronal activation and blood–brain barrier permeability of time and n-3 polyunsaturated fatty acids in mice, as measured in vivo using MEMRI. NeuroImage. 50 (4), pp. 1384-1391. https://doi.org/10.1016/j.neuroimage.2010.01.057

Random effects models for operational patient pathways
Adeyemi, S., Chaussalet, T.J., Xie, H. and Assaduzzman, M. 2010. Random effects models for operational patient pathways. Journal of Applied Statistics. 37 (4), pp. 691-701. https://doi.org/10.1080/02664760902873951

Asymmetry of information flow between volatilities across time scales
Gençay, R., Gradojevic, N., Selçuk, F. and Whitcher, B. 2010. Asymmetry of information flow between volatilities across time scales. Quantitative Finance. 10 (8), pp. 895-915. https://doi.org/10.1080/14697680903460143

A Multi-Center Randomized Proof-of-Concept Clinical Trial Applying [18F]FDG-PET for Evaluation of Metabolic Therapy with Rosiglitazone XR in Mild to Moderate Alzheimer's Disease
Tzimopoulou, S., Cunningham, V.J., Nichols, T.E., Searle, G., Bird, N.P., Mistry, P., Dixon, I.J., Hallett, W.A., Whitcher, B., Brown, A.P., Zvartau-Hind, M., Lotay, N., Lai, R.Y.K., Castiglia, M., Jeter, B., Matthews, J.C., Chen, K., Bandy, D., Reiman, E.M., Gold, M., Rabiner, E.A. and Matthews, P.M. 2010. A Multi-Center Randomized Proof-of-Concept Clinical Trial Applying [18F]FDG-PET for Evaluation of Metabolic Therapy with Rosiglitazone XR in Mild to Moderate Alzheimer's Disease. Journal of Alzheimer's Disease. 22 (4), pp. 1241-1256. https://doi.org/10.3233/jad-2010-100939

Longitudinal changes in white matter disease and cognition in the first year of the Alzheimer disease neuroimaging initiative.
Carmichael, O., Schwarz, C., Drucker, D., Fletcher, E., Harvey, D., Beckett, L., Jack, C.R., Weiner, M., DeCarli, C., Alzheimer's Disease Neuroimaging Initiative and Whitcher, B. 2010. Longitudinal changes in white matter disease and cognition in the first year of the Alzheimer disease neuroimaging initiative. Archives of Neurology. 67 (11), pp. 1370-1378. https://doi.org/10.1001/archneurol.2010.284

Reduction of total lung capacity in obese men: comparison of total intrathoracic and gas volumes
Watson, R.A., Pride, N.B., Thomas, E.L., Fitzpatrick, J., Durighel, G., McCarthy, J., Morin, S.H.X., Ind, P.W. and Bell, J.D. 2010. Reduction of total lung capacity in obese men: comparison of total intrathoracic and gas volumes. Journal of Applied Physiology. 108 (6), pp. 1605-1612. https://doi.org/10.1152/japplphysiol.01267.2009

Estimation of abdominal fat compartments by bioelectrical impedance: the validity of the ViScan measurement system in comparison with MRI
Thomas, E.L., Collins, A.L., McCarthy, J., Fitzpatrick, J., Durighel, G., Goldstone, A.P. and Bell, J.D. 2010. Estimation of abdominal fat compartments by bioelectrical impedance: the validity of the ViScan measurement system in comparison with MRI. European Journal of Clinical Nutrition. 64, pp. 525-533. https://doi.org/10.1038/ejcn.2010.18

Efficient and rapid labelling of transplanted cell populations with superparamagnetic iron oxide nanoparticles using cell surface chemical biotinylation for in vivo monitoring by MRI
So, P.W., Kalber, T., Hunter, D., Farquharson, M., Al-Ebraheem, A., Parkes, H.G., Simon, R. and Bell, J.D. 2010. Efficient and rapid labelling of transplanted cell populations with superparamagnetic iron oxide nanoparticles using cell surface chemical biotinylation for in vivo monitoring by MRI. Cell Transplantation. 19 (4), pp. 419-429. https://doi.org/10.3727/096368910X498250

Breast cancer invasion is mediated by beta-N-acetylglucosaminidase (beta-NAG) and associated with a dysregulation in the secretory pathway of cancer cells
Ramessur, K.T., Greenwell, P., Nash, R. and Dwek, M. 2010. Breast cancer invasion is mediated by beta-N-acetylglucosaminidase (beta-NAG) and associated with a dysregulation in the secretory pathway of cancer cells. British Journal of Biomedical Science. 67 (4), pp. 189-196.

Inflammatory modulation of exercise salience: using hormesis to return to a healthy lifestyle
Nunn, A.V.W., Guy, G.W., Brodie, J.S. and Bell, J.D. 2010. Inflammatory modulation of exercise salience: using hormesis to return to a healthy lifestyle. Nutrition & Metabolism. 7, p. 87. https://doi.org/10.1186/1743-7075-7-87

Chemistry of tumour targeted T1 based MRI contrast agents
Kamaly, N., Miller, A.D. and Bell, J.D. 2010. Chemistry of tumour targeted T1 based MRI contrast agents. Current Topics in Medicinal Chemistry. 10 (12), pp. 1158-1183. https://doi.org/10.2174/156802610791384199

A novel bimodal lipidic contrast agent for cellular labelling and tumour MRI
Kamaly, N., Kalber, T., Kenny, G., Bell, J.D., Jorgensen, M.R. and Miller, A.D. 2010. A novel bimodal lipidic contrast agent for cellular labelling and tumour MRI. Organic and Biomolecular Chemistry. 8, pp. 201-211. https://doi.org/10.1039/B910561A

Revealing real-time cell surface interaction analysis: a focus on lectin - cell glycan interactions
Dwek, M. 2010. Revealing real-time cell surface interaction analysis: a focus on lectin - cell glycan interactions. Discovery-Summit. Majestic Barrière Hotel, Cannes, France 22nd – 24th March 2010

Revealing real-time cell surface interaction analysis: a focus on lectin - cell glycan interactions
Dwek, M. 2010. Revealing real-time cell surface interaction analysis: a focus on lectin - cell glycan interactions. Informa Life Sciences 6th Annual Next Generation Protein Therapeutics. Sheraton Brussels Hotel, Belgium 28th – 29th September 2010

GalNAc-recognition by lectins for cancer prognostication
Dwek, M. 2010. GalNAc-recognition by lectins for cancer prognostication. 105th Annual Meeting of the Anatomische Gesellschaft. Hamburg, Germany 29th March 2010

An evaluation of breast cancer cell line sialyltransferase expression levels and assessment of possible correlation with HPA lectin binding profiles
Blaszczak, E., Greenwell, G. and Dwek, M. 2010. An evaluation of breast cancer cell line sialyltransferase expression levels and assessment of possible correlation with HPA lectin binding profiles. Horizons in Molecular Biology: International PhD Student Symposium. Göttingen, Germany 27 - 30 Sep 2010

Analysis of variability in neonatal care units: a retrospective analysis
Adeyemi, S., Demir, E., Chahed, S. and Chaussalet, T.J. 2010. Analysis of variability in neonatal care units: a retrospective analysis. in: IEEE Workshop on Health Care Management (WHCM), Venice, 18-20 February 2010 IEEE . pp. 1-6

Proton magnetic resonance spectroscopy and ultrasound for hepatic fat quantification
Mehta, S.R., Thomas, E.L., Patel, N., Crofton, M.E., McCarthy, J., Eliahoo, J., Morin, S.H.X., Fitzpatrick, J., Durighel, G., Goldstone, A.P., Johnston, D.G., Bell, J.D. and Taylor-Robinson, S.D. 2010. Proton magnetic resonance spectroscopy and ultrasound for hepatic fat quantification. Hepatology Research. 40 (4), pp. 399-406. https://doi.org/10.1111/j.1872-034X.2009.00620.x

Resistant starch improves insulin sensitivity in metabolic syndrome
Johnston, K.L., Thomas, E.L., Bell, J.D., Frost, G.S. and Robertson, M.D. 2010. Resistant starch improves insulin sensitivity in metabolic syndrome. Diabetic Medicine. 27 (4), pp. 391-397. https://doi.org/10.1111/j.1464-5491.2010.02923.x

Towards effective capacity planning in a perinatal network centre
Asaduzzaman, M., Chaussalet, T.J., Adeyemi, S., Chahed, S., Hawdon, J., Wood, D. and Robertson, N.J. 2010. Towards effective capacity planning in a perinatal network centre. Archives of Disease in Childhood. Fetal and Neonatal Edition. 95 (4), pp. F283-F287. https://doi.org/10.1136/adc.2009.161661

A sensitive assay to measure biomarker glycosylation demonstrates increased fucosylation of prostate specific antigen (PSA) in patients with prostate cancer compared with benign prostatic hyperplasia
Dwek, M., Jenks, A. and Leathem, A. 2010. A sensitive assay to measure biomarker glycosylation demonstrates increased fucosylation of prostate specific antigen (PSA) in patients with prostate cancer compared with benign prostatic hyperplasia. Clinica Chimica Acta. 411 (23-24), pp. 1935-1939. https://doi.org/10.1016/j.cca.2010.08.009

Dominant role of the p110β isoform of PI3K over p110α in energy homeostasis regulation by POMC and AgRP neurons
Al-Qassab, H., Smith, M.A., Irvine, E.E., Guillermet-Guibert, J., Claret, M., Choudhury, A.I., Selman, C., Piipari, K., Clements, M., Lingard, S., Chandarana, K., Bell, J.D., Barsh, G.S., Smith, A.J.H., Batterham, R.L., Ashford, M.L.J., Vanhaesebroeck, B. and Withers, D.J. 2009. Dominant role of the p110β isoform of PI3K over p110α in energy homeostasis regulation by POMC and AgRP neurons. Cell Metabolism. 10 (5), pp. 343-354. https://doi.org/10.1016/j.cmet.2009.09.008

Cancer prognostication using a recombinant form of the lectin from Helix pomatia agglutinin
Dwek, M., Markiv, A. and Odell, M. 2009. Cancer prognostication using a recombinant form of the lectin from Helix pomatia agglutinin. Glycobiology. 19 (11), p. 1318. https://doi.org/10.1093/glycob/cwp135

UEA-1 enables discrimination between prostate specific antigen from patients with prostate cancer and benign prostatic hyperplasia
Dwek, M., Jenks, A. and Leathem, A. 2009. UEA-1 enables discrimination between prostate specific antigen from patients with prostate cancer and benign prostatic hyperplasia. Glycobiology. 19 (11), p. 1318. https://doi.org/10.1093/glycob/cwp135

Fasting biases brain reward systems towards high-calorie foods
Goldstone, A.P., Prechtl de Hernandez, C.G., Beaver, J.D., Muhammed, K., Croese, C., Bell, G., Durighel, G., Hughes, E., Waldman, A.D., Frost, G.S. and Bell, J.D. 2009. Fasting biases brain reward systems towards high-calorie foods. European Journal of Neuroscience. 30 (8), pp. 1625-1635. https://doi.org/10.1111/j.1460-9568.2009.06949.x

Cerebral activation by fasting induces lactate accumulation in the hypothalamus
Violante, I.R., Anastasovska, J., Sanchez-Canon, G.J., Rodrigues, T.B., Righi, V., Nieto-Charques, L., Parkinson, J.R.C., Bloom, S.R., Bell, J.D. and Cerdan Sebastian 2009. Cerebral activation by fasting induces lactate accumulation in the hypothalamus. Magnetic Resonance in Medicine. 62 (2), pp. 279-283. https://doi.org/10.1002/mrm.22010

Obesity, diabetes and longevity in the Gulf: is there a Gulf metabolic syndrome?
Guy, G.W., Nunn, A.V.W., Thomas, E.L. and Bell, J.D. 2009. Obesity, diabetes and longevity in the Gulf: is there a Gulf metabolic syndrome? International Journal of Diabetes Mellitus. 1 (1), pp. 43-54. https://doi.org/10.1016/j.ijdm.2009.05.001

Differential patterns of neuronal activation in the brainstem and hypothalamus following peripheral injection of GLP-1, oxyntomodulin and lithium chloride in mice detected by manganese-enhanced magnetic resonance imaging (MEMRI)
Parkinson, J.R.C., Chaudhri, O.B., Kuo, Y.T., Field, B.C.T., Herlihy, A.H., Dhillo, W.S., Ghatei, M.A., Bloom, S.R. and Bell, J.D. 2009. Differential patterns of neuronal activation in the brainstem and hypothalamus following peripheral injection of GLP-1, oxyntomodulin and lithium chloride in mice detected by manganese-enhanced magnetic resonance imaging (MEMRI). NeuroImage. 44 (3), pp. 1022-1031. https://doi.org/10.1016/j.neuroimage.2008.09.047

Quantitative analysis of dynamic contrast-enhanced MR images based on bayesian P-splines
Schmid, V.J., Whitcher, B., Padhani, A.R. and Yang, G.-Z. 2009. Quantitative analysis of dynamic contrast-enhanced MR images based on bayesian P-splines. IEEE Transactions on Medical Imaging. 28 (6), pp. 789-798. https://doi.org/10.1109/tmi.2008.2007326

Quantifying spatial heterogeneity in dynamic contrast-enhanced MRI parameter maps
Rose, C.J., Mills, S.J., O'Connor, J.P.B., Buonaccorsi, G.A., Roberts, C., Watson, Y., Cheung, S., Zhao, S., Whitcher, B., Jackson, A. and Parker, G.J.M. 2009. Quantifying spatial heterogeneity in dynamic contrast-enhanced MRI parameter maps. Magnetic Resonance in Medicine. 62 (2), pp. 488-499. https://doi.org/10.1002/mrm.22003

A bayesian hierarchical model for the analysis of a longitudinal dynamic contrast-enhanced MRI oncology study
Schmid, V.J., Whitcher, B., Padhani, A.R., Jane Taylor, N. and Yang, G.-Z. 2009. A bayesian hierarchical model for the analysis of a longitudinal dynamic contrast-enhanced MRI oncology study. Magnetic Resonance in Medicine. 61 (1), pp. 163-174. https://doi.org/10.1002/mrm.21807

Anatomically-distinct genetic associations of APOE e{open}4 allele load with regional cortical atrophy in Alzheimer's disease
Filippini, N., Rao, A., Wetten, S., Gibson, R.A., Borrie, M., Guzman, D., Kertesz, A., Loy-English, I., Williams, J., Nichols, T., Whitcher, B. and Matthews, P.M. 2009. Anatomically-distinct genetic associations of APOE e{open}4 allele load with regional cortical atrophy in Alzheimer's disease. NeuroImage. 44 (3), pp. 724-728. https://doi.org/10.1016/j.neuroimage.2008.10.003

Variational Bayesian inference for a nonlinear forward model
Chappell, M.A., Groves, A.R., Whitcher, B. and Woolrich, M.W. 2009. Variational Bayesian inference for a nonlinear forward model. IEEE Transactions on Signal Processing. 57 (1), pp. 223-236. https://doi.org/10.1109/tsp.2008.2005752

The application of magnetic resonance imaging and spectroscopy to gene therapy
So, P.W., Bhakoo, K.K., Cox, I.J., Taylor-Robinson, S.D. and Bell, J.D. 2009. The application of magnetic resonance imaging and spectroscopy to gene therapy. in: Conn, P.M. (ed.) Essential bioimaging methods Academic Press. pp. 374-398

Diagonal-SPRITE and its applications for in vivo imaging at high field
Protti, A., Herlihy, A.H., So, P.W., Tessier, J., Kalber, T. and Bell, J.D. 2009. Diagonal-SPRITE and its applications for in vivo imaging at high field. The Open Magnetic Resonance Journal. 2, pp. 1-7. https://doi.org/10.2174/1874769800902010001

Imaging appetite regulating pathways in the central nervous system using manganese enhanced magnetic resonance imaging (MEMRI)
Parkinson, J.R.C., Chaudhri, O.B. and Bell, J.D. 2009. Imaging appetite regulating pathways in the central nervous system using manganese enhanced magnetic resonance imaging (MEMRI). Neuroendocrinology. 89 (2), pp. 121-130. https://doi.org/10.1159/000163751

Fat distribution in men of different waist girth, fitness level and exercise habit
O'Donovan, G., Thomas, E.L., McCarthy, J., Fitzpatrick, J., Durighel, G., Mehta, S.R., Morin, S.H.X., Goldstone, A.P. and Bell, J.D. 2009. Fat distribution in men of different waist girth, fitness level and exercise habit. International Journal of Obesity. 33 (12), pp. 1356-1362. https://doi.org/10.1038/ijo.2009.189

Lifestyle-induced metabolic inflexibility and accelerated ageing syndrome: insulin resistance, friend or foe?
Nunn, A.V.W., Bell, J.D. and Guy, G.W. 2009. Lifestyle-induced metabolic inflexibility and accelerated ageing syndrome: insulin resistance, friend or foe? Nutrition & Metabolism. 6, p. 16. https://doi.org/10.1186/1743-7075-6-16

Whole body magnetic resonance imaging of healthy newborn infants demonstrates increased central adiposity in Asian Indians
Modi, N., Thomas, E.L., Uthaya, S.N., Umranikar, S., Bell, J.D. and Yajnik, C. 2009. Whole body magnetic resonance imaging of healthy newborn infants demonstrates increased central adiposity in Asian Indians. Paediatric Research. 65 (5), pp. 584-587. https://doi.org/10.1203/PDR.0b013e31819d98be

Folate receptor targeted bimodal liposomes for tumor magnetic resonance imaging
Kamaly, N., Kalber, T., Thanou, M., Bell, J.D. and Miller, A.D. 2009. Folate receptor targeted bimodal liposomes for tumor magnetic resonance imaging. Bioconjugate Chemistry. 20 (4), pp. 648-655. https://doi.org/10.1021/bc8002259

A Grid implementation for profiling hospitals based on patient readmissions
Demir, E., Chaussalet, T.J., Weingarten, N. and Kiss, T. 2009. A Grid implementation for profiling hospitals based on patient readmissions. in: McClean, S.I., Millard, P.H., El-Darzi, E. and Nugent, C. (ed.) Intelligent patient management Springer.

A systematic approach in defining readmission
Demir, E. and Chaussalet, T.J. 2009. A systematic approach in defining readmission. in: Proceedings of the 22nd IEEE International Symposium on Computer-Based Medical Systems (CBMS 2009) IEEE . pp. 1-7

The analyses of individual patient pathways: investigating regional variation in COPD readmissions
Adeyemi, S., Chaussalet, T.J., Xie, H. and Asaduzzaman, M. 2009. The analyses of individual patient pathways: investigating regional variation in COPD readmissions. in: Sakalauskas, L., Skiadas, C. and Zavadskas, E.K. (ed.) Proceedings of the 13th International Conference "Applied Stochastic Models and Data Analysis", ASMDA 2009, 30 June – 3 July 2009, Vilnius, Lithuania ASMDA. pp. 316-319

Models for extracting information on patient pathways
Adeyemi, S. and Chaussalet, T.J. 2009. Models for extracting information on patient pathways. in: McClean, S.I., Millard, P.H., El-Darzi, E. and Nugent, C. (ed.) Intelligent patient management Springer.

Editorial: Applying mathematics to problems in health care: a call to pencils
Utley, M., Chaussalet, T.J. and Baker, R.D. 2009. Editorial: Applying mathematics to problems in health care: a call to pencils. IMA Journal of Management Mathematics. 20 (4), pp. 323-323. https://doi.org/10.1093/imaman/dpn036

Modelling risk of readmission with phase-type distribution and transition models
Demir, E., Chaussalet, T.J., Xie, H. and Millard, P.H. 2009. Modelling risk of readmission with phase-type distribution and transition models. IMA Journal of Management Mathematics. 20 (4), pp. 357-367. https://doi.org/10.1093/imaman/dpn032

Incidental findings in healthy control research subjects using whole-body MRI
Morin, S.H.X., Cobbold, J.F.L., Lim, A.K.P., Eliahoo, J., Thomas, E.L., Mehta, S.R., Durighel, G., Fitzpatrick, J., Bell, J.D. and Taylor-Robinson, S.D. 2009. Incidental findings in healthy control research subjects using whole-body MRI. European Journal of Radiology. 72 (3), pp. 529-533. https://doi.org/10.1016/j.ejrad.2008.08.006

Emergency readmission criterion: a technique for determining emergency readmission time window
Demir, E., Chaussalet, T.J., Xie, H. and Millard, P.H. 2008. Emergency readmission criterion: a technique for determining emergency readmission time window. IEEE Transactions on Information Technology in Biomedicine. 12 (5), pp. 644-649. https://doi.org/10.1109/TITB.2007.911311

Reproducibility of fMRI in the clinical setting: Implications for trial designs
Bosnell, R., Wegner, C., Kincses, Z.T., Korteweg, T., Agosta, F., Ciccarelli, O., De Stefano, N., Gass, A., Hirsch, J., Johansen-Berg, H., Kappos, L., Barkhof, F., Mancini, L., Manfredonia, F., Marino, S., Miller, D.H., Montalban, X., Palace, J., Rocca, M., Enzinger, C., Ropele, S., Rovira, A., Smith, S., Thompson, A., Thornton, J., Yousry, T., Whitcher, B., Filippi, M. and Matthews, P.M. 2008. Reproducibility of fMRI in the clinical setting: Implications for trial designs. NeuroImage. 42 (2), pp. 603-610. https://doi.org/10.1016/j.neuroimage.2008.05.005

A statistical framework to characterise microstructure in high angular resolution diffusion imaging
Olhede, S. and Whitcher, B. 2008. A statistical framework to characterise microstructure in high angular resolution diffusion imaging. 2008 5th IEEE international symposium on biomedical imaging: From nano to macro. Paris, France 14 - 17 May 2008 IEEE . https://doi.org/10.1109/isbi.2008.4541142

A multi-resolution census algorithm for calculating vortex statistics in turbulent flows
Whitcher, B., Lee, T.C.M., Weiss, J.B., Hoar, T.J. and Nychka, D.W. 2008. A multi-resolution census algorithm for calculating vortex statistics in turbulent flows. Journal of the Royal Statistical Society: Series C (Applied Statistics). 57 (3), pp. 293-312. https://doi.org/10.1111/j.1467-9876.2007.00614.x

Non-invasive means of measuring hepatic fat content
Mehta, S.R., Thomas, E.L., Bell, J.D., Johnston, D.G. and Taylor-Robinson, S.D. 2008. Non-invasive means of measuring hepatic fat content. World Journal of Gastroenterology. 14 (22), pp. 3476-3483. https://doi.org/10.3748/wjg.14.3476

Bimodal paramagnetic and fluorescent liposomes for cellular and tumor magnetic resonance imaging
Kamaly, N., Kalber, T., Ahmad, A., Oliver, M.H., So, P.W., Herlihy, A.H., Bell, J.D., Jorgensen, M.R. and Miller, A.D. 2008. Bimodal paramagnetic and fluorescent liposomes for cellular and tumor magnetic resonance imaging. Bioconjugate Chemistry. 19 (1), pp. 118-129. https://doi.org/10.1021/bc7001715

Modelling and performance measure of a perinatal network centre in the United Kingdom
Asaduzzaman, M. and Chaussalet, T.J. 2008. Modelling and performance measure of a perinatal network centre in the United Kingdom. in: Proceedings of the 21st IEEE International Symposium on Computer-Based Medical Systems, IEEE CBMS 2008, Jyväskylä, 17-19 June 2008 Los Alamitos, USA IEEE . pp. 506-511

A random effects sensitivity analysis for patient pathways model
Adeyemi, S. and Chaussalet, T.J. 2008. A random effects sensitivity analysis for patient pathways model. in: Proceedings of the 21st IEEE International Symposium on Computer-Based Medical Systems, IEEE CBMS 2008, Jyväskylä, 17-19 June 2008 Los Alamitos, USA IEEE . pp. 536-538

Balancing the NHS balanced scorecard!
Patel, B., Chaussalet, T.J. and Millard, P.H. 2008. Balancing the NHS balanced scorecard! European Journal of Operational Research. 185 (3), pp. 905-914. https://doi.org/10.1016/j.ejor.2006.02.056

Editorial: IMA Health 2007
Baker, R.D., Chaussalet, T.J. and Utley, M. 2008. Editorial: IMA Health 2007. Health Care Management Science. 11 (2), pp. 87-88. https://doi.org/10.1007/s10729-008-9065-8

Neonatal intrahepatocellular lipid
Thomas, E.L., Uthaya, S.N., Vasu, V., McCarthy, J., McEwan, P., Hamilton, G., Bell, J.D. and Modi, N. 2008. Neonatal intrahepatocellular lipid. Archives of Disease in Childhood. Fetal and Neonatal Edition. 93 (5), pp. F382-F383. https://doi.org/10.1136/adc.2007.127431

The temporal sequence of gut peptide-central nervous system interactions tracked in vivo by magnetic resonance imaging
Kuo, Y.T., Parkinson, J.R.C., Chaudhri, O.B., Herlihy, A.H., So, P.W., Dhillo, W.S., Small, C.J., Bloom, S.R. and Bell, J.D. 2007. The temporal sequence of gut peptide-central nervous system interactions tracked in vivo by magnetic resonance imaging. Journal of Neuroscience. 27 (45), pp. 12341-12348. https://doi.org/10.1523/JNEUROSCI.2391-07.2007

Colorectal cancer – a sticky problem
Dwek, M. 2007. Colorectal cancer – a sticky problem. Oncology News. 2 (3), pp. 19-21.

Synthesis of a novel ‘smart’ bifunctional chelating agent 1-(2-[β,d-galactopyranosyloxy]ethyl)-7-(1-carboxy-3-[4-aminophenyl]propyl)-4,10-bis(carboxymethyl)-1,4,7,10-tetraazacyclododecane (Gal-PA-DO3A-NH2) and its Gd(III) complex
Wardle, N.J., Herlihy, A.H., So, P.W., Bell, J.D. and Bligh, S.W.A. 2007. Synthesis of a novel ‘smart’ bifunctional chelating agent 1-(2-[β,d-galactopyranosyloxy]ethyl)-7-(1-carboxy-3-[4-aminophenyl]propyl)-4,10-bis(carboxymethyl)-1,4,7,10-tetraazacyclododecane (Gal-PA-DO3A-NH2) and its Gd(III) complex. Bioorganic & medicinal chemistry. 15 (14), pp. 4714-4721. https://doi.org/10.1016/j.bmc.2007.05.004

The integration of lipid-sensing and anti-inflammatory effects: how the PPARs play a role in metabolic balance
Nunn, A.V.W., Bell, J.D. and Barter, P. 2007. The integration of lipid-sensing and anti-inflammatory effects: how the PPARs play a role in metabolic balance. Nuclear Receptor. 5 (1), pp. 1-12. https://doi.org/10.1186/1478-1336-5-1

Using the wild bootstrap to quantify uncertainty in diffusion tensor imaging
Whitcher, B., Tuch, D.S., Wisco, J.J., Sorensen, A.G. and Wang, L. 2007. Using the wild bootstrap to quantify uncertainty in diffusion tensor imaging. Human Brain Mapping. 29 (3), pp. 346-362. https://doi.org/10.1002/hbm.20395

Statistical group comparison of diffusion tensors via multivariate hypothesis testing
Whitcher, B., Wisco, J.J., Hadjikhani, N. and Tuch, D.S. 2007. Statistical group comparison of diffusion tensors via multivariate hypothesis testing. Magnetic Resonance in Medicine. 57 (6), pp. 1065-1074. https://doi.org/10.1002/mrm.21229

Study-level wavelet cluster analysis and data-driven signal models in pharmacological MRI
Schwarz, A.J., Whitcher, B., Gozzi, A., Reese, T. and Bifone, A. 2007. Study-level wavelet cluster analysis and data-driven signal models in pharmacological MRI. Journal of Neuroscience Methods. 159 (2), pp. 346-360. https://doi.org/10.1016/j.jneumeth.2006.07.017

Resampling methods for improved wavelet-based multiple hypothesis testing of parametric maps in functional MRI
Şendur, L., Suckling, J., Whitcher, B. and Bullmore, E. 2007. Resampling methods for improved wavelet-based multiple hypothesis testing of parametric maps in functional MRI. NeuroImage. 37 (4), pp. 1186-1194. https://doi.org/10.1016/j.neuroimage.2007.05.057

Quantifying heterogeneity in dynamic contrast-enhanced MRI parameter maps
Rose, C.J., Mills, S., O'Connor, J.P.B., Buonaccorsi, G.A., Roberts, C., Watson, Y., Whitcher, B., Jayson, G., Jackson, A. and Parker, G.J.M. 2007. Quantifying heterogeneity in dynamic contrast-enhanced MRI parameter maps. MICCAI 2007: Medical Image Computing and Computer-Assisted Intervention – MICCAI 2007. Brisbane, Australia 29 Oct - 02 Nov 2007 Springer. https://doi.org/10.1007/978-3-540-75759-7_46

An objective method for bed capacity planning in a hospital department - a comparison with target ratio methods.
Nguyen, J.M., Six, P., Chaussalet, T.J., Antonioli, D., Lombrail, P. and Le Beux, P. 2007. An objective method for bed capacity planning in a hospital department - a comparison with target ratio methods. Methods of Information in Medicine. 46 (4), pp. 399-405. https://doi.org/10.1160/me0385

A semi-open queueing network approach to the analysis of patient flow in healthcare systems
Xie, H., Chaussalet, T.J. and Rees, M. 2007. A semi-open queueing network approach to the analysis of patient flow in healthcare systems. in: Proceedings of the 20th IEEE International Symposium on Computer-Based Medical Systems. IEEE CBMS 2007, Maribor, Slovenia, 20-22 June 2007 Los Alamitos, USA IEEE . pp. 719-724

Impact of resistant starch on body fat patterning and central appetite regulation
So, P.W., Yu, W.S., Kuo, Y.T., Wasserfall, C., Goldstone, A.P., Bell, J.D. and Frost, G.S. 2007. Impact of resistant starch on body fat patterning and central appetite regulation. PLoS ONE. 2 (12) e1309. https://doi.org/10.1371/journal.pone.0001309

Application of magnetic resonance methods to studies of gene therapy
So, P.W., Parkes, H.G. and Bell, J.D. 2007. Application of magnetic resonance methods to studies of gene therapy. Progress in Nuclear Magnetic Resonance Spectroscopy. 51 (1), pp. 49-62. https://doi.org/10.1016/j.pnmrs.2007.02.001

The application of in vivo MRI and MRS in phenomic studies of murine models of disease
So, P.W. and Bell, J.D. 2007. The application of in vivo MRI and MRS in phenomic studies of murine models of disease. in: Webb, G.A. (ed.) Modern magnetic resonance The Netherlands Springer. pp. 769-786

Determining readmission time window using mixture of generalised Erlang distribution
Demir, E., Chaussalet, T.J. and Xie, H. 2007. Determining readmission time window using mixture of generalised Erlang distribution. in: Proceedings of the 20th IEEE International Symposium on Computer-Based Medical Systems. IEEE CBMS 2007, Maribor, Slovenia, 20-22 June 2007 Los Alamitos, USA IEEE . pp. 21-26

Developing an application of an accident and emergency patient simulation modelling using an interactive framework
Codrington-Virtue, A., Chaussalet, T.J., Whittlestone, P. and Kelly, J. 2007. Developing an application of an accident and emergency patient simulation modelling using an interactive framework. in: Brailsford, S. and Harper, P.R. (ed.) Operational research for health policy: making better decisions: proceedings of the 31st Annual Conference of the European Working Group on Operational Research Applied to Health Services Oxford ; New York Peter Lang. pp. 61-76

Patients flow: a mixed-effects modelling approach to predicting discharge probabilities
Adeyemi, S., Chaussalet, T.J., Xie, H. and Millard, P.H. 2007. Patients flow: a mixed-effects modelling approach to predicting discharge probabilities. in: Proceedings of the 20th IEEE International Symposium on Computer-Based Medical Systems. IEEE CBMS 2007, Maribor, Slovenia, 20-22 June 2007 Los Alamitos, USA IEEE . pp. 725-730

Exercise training reduces fatty acid availability and improves the insulin sensitivity of glucose metabolism
Shojaee-Moradie, F., Baynes, K.C.R., Pentecost, C., Bell, J.D., Thomas, E.L., Jackson, N.C., Stolinski, M., Whyte, M., Lovell, D., Bowes, S.B., Gibney, J., Jones, R.H. and Umpleby, A.M. 2007. Exercise training reduces fatty acid availability and improves the insulin sensitivity of glucose metabolism. Diabetologia. 50 (2), pp. 404-413. https://doi.org/10.1007/s00125-006-0498-7

A simple graphical decision aid for the placement of elderly people in long-term care
Xie, H., Chaussalet, T.J., Thompson, W.A. and Millard, P.H. 2007. A simple graphical decision aid for the placement of elderly people in long-term care. Journal of the Operational Research Society. 58 (4), pp. 446-453. https://doi.org/10.1057/palgrave.jors.2602179

Predictors of axillary lymph node metastasis in breast cancer: a systematic review
Patani, N.R., Dwek, M. and Douek, M. 2007. Predictors of axillary lymph node metastasis in breast cancer: a systematic review. European Journal of Surgical Oncology. 33 (4), pp. 409-419. https://doi.org/10.1016/j.ejso.2006.09.003

Creatine supplements in patients with idiopathic inflammatory myopathies who are clinically weak after conventional pharmacologic treatment: Six-month, double-blind, randomized, placebo-controlled trial
Chung, Y.L., Alexanderson, H., Pipitone, N., Morrison, C., Dastmalchi, M., Ståhl-Hallengren, C., Richards, S., Thomas, E.L., Hamilton, G., Bell, J.D., Lundberg, I.E. and Scott, D.L. 2007. Creatine supplements in patients with idiopathic inflammatory myopathies who are clinically weak after conventional pharmacologic treatment: Six-month, double-blind, randomized, placebo-controlled trial. Arthritis & Rheumatism. 57 (4), pp. 694-702. https://doi.org/10.1002/art.22687

Identification and elimination of false-positives in an ELISA-based system for qualitative assessment of glycoconjugate binding using a selection of plant lectins.
Afrough, B., Dwek, M. and Greenwell, P. 2007. Identification and elimination of false-positives in an ELISA-based system for qualitative assessment of glycoconjugate binding using a selection of plant lectins. BioTechniques. 43 (4), pp. 458-462. https://doi.org/10.2144/000112554

Pioglitazone added to conventional lipid lowering treatment in familial combined hyperlipidaemia improves parameters of metabolic control: relation to liver, muscle and regional body fat content
Thomas, E.L., Potter, E., Tosi, I., Fitzpatrick, J., Hamilton, G., Amber, V., Hughs, R., North, C., Holvoet, P., Seed, M., Betteridge, D.J., Bell, J.D. and Naoumova, R.P. 2007. Pioglitazone added to conventional lipid lowering treatment in familial combined hyperlipidaemia improves parameters of metabolic control: relation to liver, muscle and regional body fat content. Atherosclerosis. 195 (1), pp. e181-e190. https://doi.org/10.1016/j.atherosclerosis.2007.03.043

Proteome analysis of metastatic colorectal cancer cells recognized by the lectin Helix pomatia agglutinin (HPA)
Saint-Guirons, J., Zeqiraj, E., Schumacher, U., Greenwell, P. and Dwek, M. 2007. Proteome analysis of metastatic colorectal cancer cells recognized by the lectin Helix pomatia agglutinin (HPA). Proteomics. 7 (22), pp. 4082-4089. https://doi.org/10.1002/pmic.200700434

Manganese-enhanced magnetic resonance imaging (MEMRI) without compromise of the blood–brain barrier detects hypothalamic neuronal activity in vivo
Kuo, Y.T., Herlihy, A.H., So, P.W. and Bell, J.D. 2006. Manganese-enhanced magnetic resonance imaging (MEMRI) without compromise of the blood–brain barrier detects hypothalamic neuronal activity in vivo. NMR in Biomedicine. 19 (8), pp. 1028-1034. https://doi.org/10.1002/nbm.1070

Differential hypothalamic neuronal activation following peripheral injection of GLP-1 and oxyntomodulin in mice detected by manganese-enhanced magnetic resonance imaging
Chaudhri, O.B., Parkinson, J.R.C., Kuo, Y.T., Druce, M.R., Herlihy, A.H., Bell, J.D., Dhillo, W.S., Stanley, S.A., Ghatei, M.A. and Bloom, S.R. 2006. Differential hypothalamic neuronal activation following peripheral injection of GLP-1 and oxyntomodulin in mice detected by manganese-enhanced magnetic resonance imaging. Biochemical and Biophysical Research Communications. 350 (2), pp. 298-306. https://doi.org/10.1016/j.bbrc.2006.09.033

The ICMCC second conference on "Medical and Care Compunetics"
Chaussalet, T.J. and Bos, L. 2006. The ICMCC second conference on "Medical and Care Compunetics". International Journal of Medical Informatics. 75 (9), pp. vii-viii. https://doi.org/10.1016/S1386-5056(06)00188-2

A model-based approach to the analysis of patterns of length of stay in institutional long-term care
Xie, H., Chaussalet, T.J. and Millard, P.H. 2006. A model-based approach to the analysis of patterns of length of stay in institutional long-term care. IEEE Transactions on Information Technology in Biomedicine. 10 (3), pp. 512-518. https://doi.org/10.1109/TITB.2005.863820

Wavelet-based bootstrapping of spatial patterns on a finite lattice
Whitcher, B. 2006. Wavelet-based bootstrapping of spatial patterns on a finite lattice. Computational Statistics & Data Analysis. 50 (9), pp. 2399-2421. https://doi.org/10.1016/j.csda.2004.12.016

Noninvasive brain imaging for experimental medicine in drug discovery and development: Promise and pitfalls
Whitcher, B. and Matthews, P.M. 2006. Noninvasive brain imaging for experimental medicine in drug discovery and development: Promise and pitfalls. International Journal of Pharmaceutical Medicine. 20, pp. 167-175. https://doi.org/10.2165/00124363-200620030-00003

Semi-parametric analysis of dynamic contrast-enhanced MRI using bayesian P-splines
Schmid, V.J., Whitcher, B. and Yang, G.-Z. 2006. Semi-parametric analysis of dynamic contrast-enhanced MRI using bayesian P-splines. MICCAI 2006: Medical Image Computing and Computer-Assisted Intervention – MICCAI 2006. Copenhagen, Denmark 01 - 06 Oct 2006 Springer. https://doi.org/10.1007/11866565_83

Bayesian methods for pharmacokinetic models in dynamic contrast-enhanced magnetic resonance imaging
Schmid, V.J., Whitcher, B., Padhani, A.R., Taylor, N.J. and Yang, G.-Z. 2006. Bayesian methods for pharmacokinetic models in dynamic contrast-enhanced magnetic resonance imaging. IEEE Transactions on Medical Imaging. 25 (12), pp. 1627-1636. https://doi.org/10.1109/tmi.2006.884210

A resilient, low-frequency, small-world human brain functional network with highly connected association cortical hubs
Achard, S., Salvador, R., Whitcher, B., Suckling, J. and Bullmore, E. 2006. A resilient, low-frequency, small-world human brain functional network with highly connected association cortical hubs. Journal of Neuroscience. 26 (1), pp. 63-72. https://doi.org/10.1523/jneurosci.3874-05.2006

Co-deposition of salmeterol and fluticasone propionate by a combination inhaler
Theophilus, A., Moore, A., Prime, D., Rossomanno, S., Whitcher, B. and Chrystyn, H. 2006. Co-deposition of salmeterol and fluticasone propionate by a combination inhaler. International Journal of Pharmaceutics. 313 (1-2), pp. 14-22. https://doi.org/10.1016/j.ijpharm.2006.01.018

Prediction of specific absorption rate in mother and fetus associated with MRI examinations during pregnancy
Hand, J.W., Li, Y., Thomas, E.L., Rutherford, M.A. and Hajnal, J.V. 2006. Prediction of specific absorption rate in mother and fetus associated with MRI examinations during pregnancy. Magnetic Resonance in Medicine. 55 (4), pp. 883-93. https://doi.org/10.1002/mrm.20824

Breast cancer proteomics using two-dimensional electrophoresis: studying the breast cancer proteome
Dwek, M.V. and Rawlings, S.L. 2006. Breast cancer proteomics using two-dimensional electrophoresis: studying the breast cancer proteome. in: Brooks, S. and Harris, A. (ed.) Breast Cancer Research Protocols New Jersey, USA Humana Press. pp. 231-243

Effect of nutritional counselling on hepatic, muscle and adipose tissue fat content and distribution in non-alcoholic fatty liver disease
Thomas, E.L., Brynes, A.E., Hamilton, G., Patel, N., Spong, A., Goldin, R.D., Frost, G.S., Bell, J.D. and Taylor-Robinson, S.D. 2006. Effect of nutritional counselling on hepatic, muscle and adipose tissue fat content and distribution in non-alcoholic fatty liver disease. World Journal of Gastroenterology. 12 (36), pp. 5813-5819. https://doi.org/10.3748/wjg.v12.i36.5813

Intra-cellular fat accumulation: mechanisms and implications for health
Thomas, E.L. and Bell, J.D. 2006. Intra-cellular fat accumulation: mechanisms and implications for health. International Journal of Body Composition Research. 4 (1), pp. 27-37.

A proteomic approach to identify the integrins α 6 and α V as HPA binding partners in the metastatic colorectal cancer cell line HT29
Saint-Guirons, J., Zeqiraj, E., Greenwell, P. and Dwek, M. 2006. A proteomic approach to identify the integrins α 6 and α V as HPA binding partners in the metastatic colorectal cancer cell line HT29. Molecular and Cellular Proteomics. 5 (10 (supplement)), p. S148.

MAGfect: a novel liposome formulation for MRI labelling and visualization of cells
Oliver, M.H., Ahmad, A., Kamaly, N., Perouzel, E., Caussin, A., Keller, M., Herlihy, A.H., Bell, J.D., Miller, A.D. and Jorgensen, M.R. 2006. MAGfect: a novel liposome formulation for MRI labelling and visualization of cells. Organic and Biomolecular Chemistry. 4 (18), pp. 3489-3497. https://doi.org/10.1039/B605394G

A method for determining an emergency readmission time window for better patient management
Demir, E., Chaussalet, T.J., Xie, H. and Millard, P.H. 2006. A method for determining an emergency readmission time window for better patient management. in: Lee, D.J., Nutter, B., Antani, S., Mitra, S. and Archibald, J. (ed.) Nineteenth IEEE International Symposium on Computer-Based Medical Systems: 22-23 June June 2006, Salt Lake City, Utah. Proceedings Las Alamitos, USA IEEE . pp. 789-793

A system for patient management based discrete-event simulation and hierarchical clustering
Codrington-Virtue, A., Chaussalet, T.J., Millard, P.H., Whittlestone, P. and Kelly, J. 2006. A system for patient management based discrete-event simulation and hierarchical clustering. in: Lee, D.J., Nutter, B., Antani, S., Mitra, S. and Archibald, J. (ed.) Nineteenth IEEE International Symposium on Computer-Based Medical Systems: 22-23 June 2006, Salt Lake City, Utah. Proceedings Las Alamitos, USA IEEE . pp. 800-804

A closed queueing network approach to the analysis of patient flow in health care systems
Chaussalet, T.J., Xie, H. and Millard, P.H. 2006. A closed queueing network approach to the analysis of patient flow in health care systems. Methods of Information in Medicine. 45 (5), pp. 492-497.

A software tool to aid long-term care budget planning at local authority level
Xie, H., Chaussalet, T.J., Toffa, S.E. and Crowther, P. 2006. A software tool to aid long-term care budget planning at local authority level. International Journal of Medical Informatics. 75 (9), pp. 664-670. https://doi.org/10.1016/j.ijmedinf.2006.04.009

Six methodological steps to build medical data warehouses for research
Szirbik, N., Pelletier, C. and Chaussalet, T.J. 2006. Six methodological steps to build medical data warehouses for research. International Journal of Medical Informatics. 75 (9), pp. 683-691. https://doi.org/10.1016/j.ijmedinf.2006.04.003

Determinants of adiposity during preweaning postnatal growth in appropriately grown and growth-restricted term infants
Modi, N., Thomas, E.L., Harrington, T.A.M., Uthaya, S.N., Doré, C.J. and Bell, J.D. 2006. Determinants of adiposity during preweaning postnatal growth in appropriately grown and growth-restricted term infants. Pediatric Research. 60 (3), pp. 345-348. https://doi.org/10.1203/01.pdr.0000232732.93000.52

Critical role for peptide YY in protein-mediated satiation and body-weight regulation
Batterham, R.L., Heffron, H., Kapoor, S., Chivers, J.E., Chandarana, K., Herzog, H., le Roux, C.W., Thomas, E.L., Bell, J.D. and Withers, D.J. 2006. Critical role for peptide YY in protein-mediated satiation and body-weight regulation. Cell Metabolism. 4 (3), pp. 223-233. https://doi.org/10.1016/j.cmet.2006.08.001

Muscle metabolites, detected in urine by proton spectroscopy, correlate with disease damage in juvenile idiopathic inflammatory myopathies
Chung, Y.L., Rider, L.G., Bell, J.D., Summers, R.M., Zemel, L.S., Rennebohm, R.M., Passo, M.H., Hicks, J., Miller, F.W. and Scott, D.L. 2005. Muscle metabolites, detected in urine by proton spectroscopy, correlate with disease damage in juvenile idiopathic inflammatory myopathies. Arthritis & Rheumatology. 53 (4), pp. 565-570. https://doi.org/10.1002/art.21331

Generic method for imaging transgene expression
So, P.W., Hotee, S., Herlihy, A.H. and Bell, J.D. 2005. Generic method for imaging transgene expression. Magnetic Resonance in Medicine. 54 (1), pp. 218-221. https://doi.org/10.1002/mrm.20522

On the use of multi-state multi-census techniques for modelling the survival of elderly people in institutional long-term care
Pelletier, C., Chaussalet, T.J. and Xie, H. 2005. On the use of multi-state multi-census techniques for modelling the survival of elderly people in institutional long-term care. IMA Journal of Management Mathematics. 16 (3), pp. 255-264. https://doi.org/10.1093/imaman/dpi021

Adiposity induced by adenovirus 5 inoculation
So, P.W., Herlihy, A.H. and Bell, J.D. 2005. Adiposity induced by adenovirus 5 inoculation. International Journal of Obesity. 29 (6), pp. 603-606. https://doi.org/10.1038/sj.ijo.0802917

In vivo measurements of T1 relaxation times in mouse brain associated with different modes of systemic administration of manganese chloride
Kuo, Y.T., Herlihy, A.H., So, P.W., Bhakoo, K.K. and Bell, J.D. 2005. In vivo measurements of T1 relaxation times in mouse brain associated with different modes of systemic administration of manganese chloride. Journal of Magnetic Resonance Imaging. 21 (4), pp. 334-339. https://doi.org/10.1002/jmri.20285

The role of insulin receptor substrate 2 in hypothalamic and β cell function
Choudhury, A.I., Heffron, H., Smith, M.A., Al-Qassab, H., Xu, A.W., Selman, C., Simmgen, M., Clements, M., Claret, M., MacColl, G., Bedford, D.C., Hisadome, K., Diakonov, I., Moosajee, V., Bell, J.D., Speakman, J.R., Batterham, R.L., Barsh, G.S., Ashford, M.L.J. and Withers, D.J. 2005. The role of insulin receptor substrate 2 in hypothalamic and β cell function. Journal of Clinical Investigation. 115 (4), pp. 940-950. https://doi.org/10.1172/JCI24445

Phosphorus-31 brain MR spectroscopy in women during and after pregnancy compared with nonpregnant control subjects
Holdcroft, A., Hall, L., Hamilton, G., Counsell, S.J., Bydder, G.M. and Bell, J.D. 2005. Phosphorus-31 brain MR spectroscopy in women during and after pregnancy compared with nonpregnant control subjects. American Journal of Neuroradiology. 26 (2), pp. 352-356.

Veganism and its relationship with insulin resistance and intramyocellular lipid
Goff, L.M., Bell, J.D., So, P.W., Dornhorst, A. and Frost, G.S. 2005. Veganism and its relationship with insulin resistance and intramyocellular lipid. European Journal of Clinical Nutrition. 59 (2), pp. 291-298. https://doi.org/10.1038/sj.ejcn.1602076

Time-varying spectral analysis in neurophysiological time series using Hilbert wavelet pairs
Whitcher, Brandon, Craigmile, Peter F. and Brown, Peter 2005. Time-varying spectral analysis in neurophysiological time series using Hilbert wavelet pairs. Signal Processing. 85 (11), pp. 2065-2081. https://doi.org/10.1016/j.sigpro.2005.07.002

Wavelet-based cluster analysis: Data-driven grouping of voxel time courses with application to perfusion-weighted and pharmacological MRI of the rat brain
Whitcher, B., Schwarz, A.J., Barjat, H., Smart, S.C., Grundy, R.I. and James, M.F. 2005. Wavelet-based cluster analysis: Data-driven grouping of voxel time courses with application to perfusion-weighted and pharmacological MRI of the rat brain. NeuroImage. 24 (2), pp. 281-295. https://doi.org/10.1016/j.neuroimage.2004.08.022

Multiple hypothesis mapping of functional MRI data in orthogonal and complex wavelet domains
Şendur, L., Maxim, V., Whitcher, B. and Bullmore, E. 2005. Multiple hypothesis mapping of functional MRI data in orthogonal and complex wavelet domains. IEEE Transactions on Signal Processing. 53 (9), pp. 3413-3426. https://doi.org/10.1109/tsp.2005.853098

Multiscale systematic risk
Gençay, R., Selçuk, F. and Whitcher, B. 2005. Multiscale systematic risk. Journal of International Money and Finance. 24 (1), pp. 55-70. https://doi.org/10.1016/j.jimonfin.2004.10.003

Statistical analysis of pharmacokinetic models in dynamic contrast-enhanced magnetic resonance imaging.
Schmid, V.J., Whitcher, B.J., Yang, G.Z., Taylor, N.J., Padhani, A.R. and Whitcher, B. 2005. Statistical analysis of pharmacokinetic models in dynamic contrast-enhanced magnetic resonance imaging. MICCAI 2005: Medical Image Computing and Computer-Assisted Intervention – MICCAI 2005. Palm Springs, CA, USA 26 - 29 Oct 2005 Springer. https://doi.org/10.1007/11566489_109

Confocal microscopy for the identification of glycosylation changes associated with metastatic colorectal cancer
Zeqiraj, E., Saint-Guirons, J., Kerrigan, M.J.P. and Dwek, M. 2005. Confocal microscopy for the identification of glycosylation changes associated with metastatic colorectal cancer. The Molecular Biology of Colorectal Cancer. UBHT Education Centre, Bristol, UK 10 - 11 Mar 2005

A software tool to aid budget planning for long-term care at local authority level
Xie, H., Chaussalet, T.J., Toffa, S.E. and Crowther, P. 2005. A software tool to aid budget planning for long-term care at local authority level. in: Bos, L., Laxminarayan, S. and Marsh, A.J. (ed.) Medical and care compunetics 2 Oxford, UK IOS Press.

A tool for studying the effects of residents' attributes on patterns of length of stay in long-term care
Xie, H., Chaussalet, T.J. and Millard, P.H. 2005. A tool for studying the effects of residents' attributes on patterns of length of stay in long-term care. in: Tsymbal, A. and Cunningham, P. (ed.) Proceedings of the 18th IEEE Symposium on Computer-Based Medical Systems: 23-25 June 2005, Dublin, Ireland USA IEEE . pp. 473-478

Crossing heterogeneous information sources for better analysis in long term care for elderly people
Pelletier, C., Szirbik, N. and Chaussalet, T.J. 2005. Crossing heterogeneous information sources for better analysis in long term care for elderly people. in: Bos, L., Laxminarayan, S. and Marsh, A.J. (ed.) Medical and care compunetics 2 Oxford, UK IOS Press.

The metabolic role of methymalonyl CoA mutase in Escherichia coli
Kannan, S.M., Dwek, M., Bucke, C. and Roy, I. 2005. The metabolic role of methymalonyl CoA mutase in Escherichia coli. Proceedings of Viteomics: structure and function of vitamins and cofactors. Cambridge, UK 2005

Structure/function of N-glycans
Dwek, M. 2005. Structure/function of N-glycans. in: Redei, G.P. (ed.) Encyclopedic dictionary of genetics, genomics, and proteomics. 2nd edition Hoboken, USA Wiley.

Glycoproteomics
Dwek, M. 2005. Glycoproteomics. in: Redei, G.P. (ed.) Encyclopedic dictionary of genetics, genomics, and proteomics. 2nd edition Hoboken, USA Wiley.

An interactive framework for developing simulation models of hospital accident and emergency services
Codrington-Virtue, A., Whittlestone, P., Kelly, J. and Chaussalet, T.J. 2005. An interactive framework for developing simulation models of hospital accident and emergency services. in: Bos, L., Laxminarayan, S. and Marsh, A.J. (ed.) Medical and care compunetics 2 Oxford, UK IOS Press.

A continuous time Markov model for the length of stay of elderly people in institutional long-term care
Xie, H., Chaussalet, T.J. and Millard, P.H. 2005. A continuous time Markov model for the length of stay of elderly people in institutional long-term care. Journal of the Royal Statistical Society: Series A. 168 (1), pp. 51-61. https://doi.org/10.1111/j.1467-985X.2004.00335.x

Hepatic triglyceride content and its relation to body adiposity: a magnetic resonance imaging and proton magnetic resonance spectroscopy study
Thomas, E.L., Hamilton, G., Patel, N., O'Dwyer, R., Doré, C.J., Goldin, R.D., Bell, J.D. and Taylor-Robinson, S.D. 2005. Hepatic triglyceride content and its relation to body adiposity: a magnetic resonance imaging and proton magnetic resonance spectroscopy study. Gut. 54 (1), pp. 122-127. https://doi.org/10.1136/gut.2003.036566

Altered adiposity after extremely preterm birth
Uthaya, S.N., Thomas, E.L., Hamilton, G., Doré, C.J., Bell, J.D. and Modi, N. 2005. Altered adiposity after extremely preterm birth. Pediatric Research. 57 (2), pp. 211-215. https://doi.org/10.1203/01.PDR.0000148284.58934.1C

A framework for predicting gross institutional long-term care cost arising from known commitments at local authority level
Pelletier, C., Chaussalet, T.J. and Xie, H. 2005. A framework for predicting gross institutional long-term care cost arising from known commitments at local authority level. Journal of the Operational Research Society. 56 (2), pp. 144-152. https://doi.org/10.1057/palgrave.jors.2601892

Excess visceral and hepatic adipose tissue in Turner syndrome determined by magnetic resonance imaging: estrogen deficiency associated with hepatic adipose content
Ostberg, J.E., Thomas, E.L., Hamilton, G., Attar, M.J.H., Bell, J.D. and Conway, G.S. 2005. Excess visceral and hepatic adipose tissue in Turner syndrome determined by magnetic resonance imaging: estrogen deficiency associated with hepatic adipose content. Journal of Clinical Endocrinology and Metabolism. 90 (5), pp. 2631-2635. https://doi.org/10.1210/jc.2004-1939

Contrast enhancement of short T2 tissues using ultrashort TE (UTE) pulse sequences
Robson, M.D., Gatehouse, P.D., So, P.W., Bell, J.D. and Bydder, G.M. 2004. Contrast enhancement of short T2 tissues using ultrashort TE (UTE) pulse sequences. Clinical Radiology. 59 (8), pp. 720-726. https://doi.org/10.1016/j.crad.2003.09.025

Wavelet-based estimation for seasonal long-memory processes
Whitcher, B. 2004. Wavelet-based estimation for seasonal long-memory processes. Technometrics. 46 (2), pp. 225-238. https://doi.org/10.1198/004017004000000275

Wavelets and functional magnetic resonance imaging of the human brain
Bullmore, E., Fadili, J., Maxim, V., Şendur, L., Whitcher, Brandon, Suckling, J., Brammer, M. and Breakspear, M. 2004. Wavelets and functional magnetic resonance imaging of the human brain. NeuroImage. 23 (1), pp. S234-S249. https://doi.org/10.1016/j.neuroimage.2004.07.012

Identifying and tracking turbulence structures
Storlie, C., Davis, C., Hoar, T., Lee, T., Nychka, D., Weiss, J.B. and Whitcher, Brandon 2004. Identifying and tracking turbulence structures. 38th Asilomar Conference on Signals, Systems and Computers. California, USA 07-10 IEEE . https://doi.org/10.1109/ACSSC.2004.1399449

Adipose tissue magnetic resonance imaging in the newborn
Uthaya, S.N., Bell, J.D. and Modi, N. 2004. Adipose tissue magnetic resonance imaging in the newborn. Hormone Research. 62 (sup.3), pp. 143-148.

Nuclear receptor corepressor RIP140 regulates fat accumulation
Leonardsson, G., Steel, J.H., Christian, M., Pocock, V., Milligan, S., Bell, J.D., So, P.W., Medina-Gomez, G., Vidal-Puig, A., White, R. and Parker, M.G. 2004. Nuclear receptor corepressor RIP140 regulates fat accumulation. Proceedings of the National Academy of Sciences. 101 (22), pp. 8437-8442. https://doi.org/10.1073/pnas.0401013101

Harnessing changes in cellular glycosylation in new cancer treatment strategies.
Dwek, M.V. and Brooks, S.A. 2004. Harnessing changes in cellular glycosylation in new cancer treatment strategies. Current Cancer Drug Targets. 4 (5), pp. 425-442. https://doi.org/10.2174/1568009043332899

Integrating data on the long-term care for elderly people from heterogeneous sources in support of research
Chaussalet, T.J. and Thompson, W.A. 2004. Integrating data on the long-term care for elderly people from heterogeneous sources in support of research. in: Proceedings of the 10th Mediterranean Conference of the International Federation for Medical and Biological Engineering (MEDICON 2004), Ischia, Italy, 31 Jul - 5 Aug 2004 Ghedimedia.

The application of magnetic resonance imaging and spectroscopy to gene therapy
Bhakoo, K.K., Bell, J.D., Cox, I.J. and Taylor-Robinson, S.D. 2004. The application of magnetic resonance imaging and spectroscopy to gene therapy. in: Ashkenazi, A., Wells, J.A. and Yuan, J. (ed.) Methods in enzymology Elsevier.

Distribution of adipose tissue in the newborn
Harrington, T.A.M., Thomas, E.L., Modi, N., Frost, G.S. and Bell, J.D. 2004. Distribution of adipose tissue in the newborn. Pediatric Research. 55 (3), pp. 437-441. https://doi.org/10.1203/01.PDR.0000111202.29433.2D

Familial partial lipodystrophy associated with compound heterozygosity for novel mutations in the LMNA gene
Savage, D.B., McFarlane, I.A., Barroso, I., Soos, M.A., Powlson, A., Thomas, E.L., Bell, J.D., Scobie, I., Belchetz, P.E., Kelly, W.F., Halsall, D.J., Schafer, A.J. and O’Rahilly, S. 2004. Familial partial lipodystrophy associated with compound heterozygosity for novel mutations in the LMNA gene. Diabetologia. 47 (4), pp. 753-756. https://doi.org/10.1007/s00125-004-1360-4

Elevated fasting plasma ghrelin in Prader-Willi Syndrome adults is not solely explained by their reduced visceral adiposity and insulin resistance
Goldstone, A.P., Thomas, E.L., Brynes, A.E., Castroman, G., Edwards, R., Ghatei, M.A., Frost, G.S., Holland, A., Grossman, A.B., Korbonits, M., Bloom, S.R. and Bell, J.D. 2004. Elevated fasting plasma ghrelin in Prader-Willi Syndrome adults is not solely explained by their reduced visceral adiposity and insulin resistance. Journal of Clinical Endocrinology and Metabolism. 89 (4), pp. 1718-1726. https://doi.org/10.1210/jc.2003-031118

N-acetyl aspartate estimation: a potential method for determining neuronal loss in the transmissible spongiform encephalopathies
Chung, Y.L., Barr, J., Bhakoo, K.K., Williams, S.C.R., Bell, J.D. and Fraser, J.R. 2003. N-acetyl aspartate estimation: a potential method for determining neuronal loss in the transmissible spongiform encephalopathies. Neuropathology and Applied Neurobiology. 29 (5), pp. 445-450. https://doi.org/10.1046/j.1365-2990.2003.00438.x

Urinary levels of creatine and other metabolites in the assessment of polymyositis and dermatomyositis
Chung, Y.L., Wassif, W.S., Bell, J.D., Hurley, M. and Scott, D.L. 2003. Urinary levels of creatine and other metabolites in the assessment of polymyositis and dermatomyositis. Rheumatology. 42 (2), pp. 298-303. https://doi.org/10.1093/rheumatology/keg084

Systematic risk and timescales
Gençay, R., Selçuk, F. and Whitcher, B. 2003. Systematic risk and timescales. Quantitative Finance. 3 (2), pp. 108-116. https://doi.org/10.1088/1469-7688/3/2/305

A wavelet solution to the spurious regression of fractionally differenced processes
Fan, Y. and Whitcher, B. 2003. A wavelet solution to the spurious regression of fractionally differenced processes. Applied Stochastic Models in Business and Industry. 19 (3). https://doi.org/10.1002/asmb.497

Stochastic Multiresolution Models for Turbulence
Whitcher, Brandon, Weiss, J.B., Nychka, D.W. and Hoar, T.J. 2003. Stochastic Multiresolution Models for Turbulence. in: Recent Advances and Trends in Nonparametric Statistics Elsevier. pp. 497-509

Time for a new approach for reporting herbal medicine adverse events?
Peters, D., Donaldson, J., Chaussalet, T.J., Toffa, S.E., Whitehouse, J., Carroll, D. and Barry, P. 2003. Time for a new approach for reporting herbal medicine adverse events? Journal of Alternative & Complementary Medicine. 9 (5), pp. 607-609.

Modelling survival in long term care of older people
Pelletier, C., Chaussalet, T.J. and Millard, P.H. 2003. Modelling survival in long term care of older people. 1st MEDINF International Conference on Medical Informatics and Engineering (MEDINF 2003). Craiova, Romania 06-09 Oct 2003

Hypothalamic neuropeptides and regulation of fat mass in Prader-Willi syndrome
Goldstone, A.P., Unmehopa, U.A., Thomas, E.L., Brynes, A.E., Bell, J.D., Frost, G.S., Ghatei, M.A., Holland, A., Bloom, S.R. and Swaab, D.F. 2003. Hypothalamic neuropeptides and regulation of fat mass in Prader-Willi syndrome. in: Eiholzer, U., l’Allemand, D. and Zipf, W.B. (ed.) Prader-Willi syndrome as a model for obesity: international symposium, Zurich, October 18-19, 2002 Karger Medical and Scientific Publishers. pp. 31-43

Glycoproteomics
Dwek, M. and Mills, P. 2003. Glycoproteomics. in: Redei, G.P. (ed.) Encyclopedic dictionary of genetics, genomics, and proteomics Chichester, UK Wiley.

Structure/function of N-glycans
Brooks, S. and Dwek, M. 2003. Structure/function of N-glycans. in: Redei, G.P. (ed.) Encyclopedic dictionary of genetics, genomics, and proteomics Chichester, UK Wiley.

Influence of undersampling on magnetic resonance imaging measurements of intra-abdominal adipose tissue
Thomas, E.L. and Bell, J.D. 2003. Influence of undersampling on magnetic resonance imaging measurements of intra-abdominal adipose tissue. International Journal of Obesity. 27 (2), pp. 211-218. https://doi.org/10.1038/sj.ijo.802229

Carbohydrate-induced manipulation of insulin sensitivity independently of intramyocellular lipids
Goff, L.M., Frost, G.S., Hamilton, G., Thomas, E.L., Dhillo, W.S., Dornhorst, A. and Bell, J.D. 2003. Carbohydrate-induced manipulation of insulin sensitivity independently of intramyocellular lipids. British Journal of Nutrition. 89 (3), pp. 365-375. https://doi.org/10.1079/BJN2002789

Human metabolic syndrome resulting from dominant-negative mutations in the nuclear receptor peroxisome proliferator-activated receptor-γ
Savage, D.B., Tan, G.D., Acerini, C.L., Jebb, S.A., Agostini, M., Gurnell, M., Williams, R.L., Umpleby, A.M., Thomas, E.L., Bell, J.D., Dixon, A.K., Dunne, F., Boiani, R., Cinti, S., Vidal-Puig, A., Karpe, F., Chatterjee, V.K.K. and O'Rahilly, S. 2003. Human metabolic syndrome resulting from dominant-negative mutations in the nuclear receptor peroxisome proliferator-activated receptor-γ. Diabetes. 52 (4), p. 910. https://doi.org/10.2337/diabetes.52.4.910

Proteome analysis enables separate clustering of normal breast, benign breast and breast cancer tissues
Dwek, M. and Alaiya, A.A. 2003. Proteome analysis enables separate clustering of normal breast, benign breast and breast cancer tissues. British Journal of Cancer. 89 (2), pp. 305-307. https://doi.org/10.1038/sj.bjc.6601008

Modelling decisions of a multidisciplinary panel for admission to long-term care
Xie, H., Chaussalet, T.J., Thompson, W.A. and Millard, P.H. 2002. Modelling decisions of a multidisciplinary panel for admission to long-term care. Health Care Management Science. 5 (4), pp. 291-295. https://doi.org/10.1023/A:1020338308191

Testing for homogeneity of variance in time series: Long memory, wavelets, and the Nile River
Whitcher, Brandon, Byers, S.D., Guttorp, P. and Percival, D.B. 2002. Testing for homogeneity of variance in time series: Long memory, wavelets, and the Nile River. Water Resources Research. 38 (5), pp. 12-1 - 12-16. https://doi.org/10.1029/2001wr000509

Fast and reproducible method for the direct quantitation of adipose tissue in newborn infants
Harrington, T.A.M., Thomas, E.L., Modi, N., Frost, G.S., Coutts, G.A. and Bell, J.D. 2002. Fast and reproducible method for the direct quantitation of adipose tissue in newborn infants. Lipids. 37 (1), pp. 95-100. https://doi.org/10.1007/s11745-002-0868-4

Current perspectives in cancer proteomics
Dwek, M.V. and Rawlings, S.L. 2002. Current perspectives in cancer proteomics. Molecular Biotechnology. 22 (2), pp. 139-152. https://doi.org/10.1385/mb:22:2:139

Functional and molecular glycobiology
Brooks, S., Dwek, M. and Schumacher, U. 2002. Functional and molecular glycobiology. Oxford, UK BIOS Scientific.

Use of proteomic methodology for the characterization of human milk fat globular membrane proteins
Charlwood, J., Hanrahan, S., Tyldesley, R., Langridge, J., Dwek, M. and Camilleri, P. 2002. Use of proteomic methodology for the characterization of human milk fat globular membrane proteins. Analytical Biochemistry. 301 (2), pp. 314-324. https://doi.org/10.1006/abio.2001.5498

Resting metabolic rate, plasma leptin concentrations, leptin receptor expression, and adipose tissue measured by whole-body magnetic resonance imaging in women with Prader-Willi syndrome
Goldstone, A.P., Brynes, A.E., Thomas, E.L., Bell, J.D., Frost, G.S., Holland, A., Ghatei, M.A. and Bloom, S.R. 2002. Resting metabolic rate, plasma leptin concentrations, leptin receptor expression, and adipose tissue measured by whole-body magnetic resonance imaging in women with Prader-Willi syndrome. American Journal of Clinical Nutition. 75 (3), pp. 468-475. https://doi.org/10.1093/ajcn/75.3.468

Letter: Digenic inheritance of severe insulin resistance in a human pedigree
Savage, D.B., Agostini, M., Barroso, I., Gurnell, M., Luan, J.A., Meirhaeghe, A., Harding, A.H., Ihrke, G., Rajanayagam, O., Soos, M.A., George, S., Birger, D., Thomas, E.L., Bell, J.D., Meera, K., Ross, R.J., Vidal-Puig, A., Wareham, N.J., O'Rahilly, S., Chatterjee, V.K.K. and Schafer, A.J. 2002. Letter: Digenic inheritance of severe insulin resistance in a human pedigree. Nature Genetics. 31 (4), pp. 379-384. https://doi.org/10.1038/ng926

Evidence for altered hepatic gluconeogenesis in patients with cirrhosis using in vivo 31-phosphorus magnetic resonance spectroscopy
Changani, K.K., Jalan, R., Cox, I.J., Ala-Korpela, M., Bhakoo, K.K., Taylor-Robinson, S.D. and Bell, J.D. 2001. Evidence for altered hepatic gluconeogenesis in patients with cirrhosis using in vivo 31-phosphorus magnetic resonance spectroscopy. Gut. 49 (4), pp. 557-564. https://doi.org/10.1136/gut.49.4.557

Data requirements in a model of the natural history of Alzheimer's disease
Chaussalet, T.J. and Thompson, W.A. 2001. Data requirements in a model of the natural history of Alzheimer's disease. Health Care Management Science. 4 (1), pp. 13-19. https://doi.org/10.1023/A:1009689329661

Scaling properties of foreign exchange volatility
Gençay, R., Selçuk, F. and Whitcher, Brandon 2001. Scaling properties of foreign exchange volatility. Physica A: Statistical Mechanics and its Applications. 289 (1-2), pp. 249-266. https://doi.org/10.1016/s0378-4371(00)00456-8

Simulating gaussian stationary processes with unbounded spectra
Whitcher, B. 2001. Simulating gaussian stationary processes with unbounded spectra. Journal of Computational and Graphical Statistics. 10 (1), pp. 112-134. https://doi.org/10.1198/10618600152418674

Differentiating intraday seasonalities through wavelet multi-scaling
Gençay, R., Selçuk, F. and Whitcher, B. 2001. Differentiating intraday seasonalities through wavelet multi-scaling. Physica A: Statistical Mechanics and its Applications. 289 (3-4), pp. 543-556. https://doi.org/10.1016/s0378-4371(00)00463-5

Subgroup analyses of cost of care in a Markov model of the natural history of Alzheimer's disease
Thompson, W.A. and Chaussalet, T.J. 2001. Subgroup analyses of cost of care in a Markov model of the natural history of Alzheimer's disease. in: Simulation in the Health and Medical Sciences 2001: Proceedings of the 2001 Western Multiconference, January 7-11 2001, Phoenix, Arizona California, USA Society for Computer Simulation. pp. 41-44

Helix pomatia agglutinin lectin-binding oligosaccharides of aggressive breast cancer.
Dwek, M., Ross, H.A., Streets, A.J., Brooks, S.A., Adam, E., Titcomb, A., Woodside, J.V., Schumacher, U. and Leathem, A.J. 2001. Helix pomatia agglutinin lectin-binding oligosaccharides of aggressive breast cancer. International Journal of Cancer. 95 (2), pp. 79-85. https://doi.org/10.1002/1097-0215(20010320)95:2<79::aid-ijc1014>3.0.co;2-e

Editorial: Modelling the process of care
Chaussalet, T.J. and El-Darzi, E. 2001. Editorial: Modelling the process of care. Health Care Management Science. 4 (1), p. 5. https://doi.org/10.1023/A:1009659711914

Proteome and glycosylation mapping identifies post-translational modifications associated with aggressive breast cancer.
Dwek, M.V., Ross, H.A. and Leathem, A.J. 2001. Proteome and glycosylation mapping identifies post-translational modifications associated with aggressive breast cancer. Proteomics. 1 (6), pp. 756-763. https://doi.org/10.1002/1615-9861(200106)1:6<756::aid-prot756>3.0.co;2-x

Visceral adipose tissue and metabolic complications of obesity are reduced in Prader-Willi syndrome female adults: evidence for novel influences on body fat distribution
Goldstone, A.P., Thomas, E.L., Brynes, A.E., Bell, J.D., Frost, G.S., Saeed, N., Hajnal, J.V., Howard, J.K., Holland, A. and Bloom, S.R. 2001. Visceral adipose tissue and metabolic complications of obesity are reduced in Prader-Willi syndrome female adults: evidence for novel influences on body fat distribution. Journal of Clinical Endocrinology and Metabolism. 86 (9), pp. 4330-4338. https://doi.org/10.1210/jc.86.9.4330

Investigation of human low-density lipoprotein by 1H nuclear magnetic resonance spectroscopy:  mobility of phosphatidylcholine and sphingomyelin headgroups characterizes the surface layer
Murphy, H.C., Burns, S.P., White, J.J., Bell, J.D. and Iles, R.A. 2000. Investigation of human low-density lipoprotein by 1H nuclear magnetic resonance spectroscopy:  mobility of phosphatidylcholine and sphingomyelin headgroups characterizes the surface layer. Biochemistry. 39 (32), pp. 9763-9770. https://doi.org/10.1021/bi0000115

Bioenergetic targeting during organ preservation: 31P magnetic resonance spectroscopy investigations into the use of fructose to sustain hepatic ATP turnover during cold hypoxia in porcine livers
Changani, K.K., Fuller, B.J., Bell, J.D., Taylor-Robinson, S.D. and Davidson, B.R. 2000. Bioenergetic targeting during organ preservation: 31P magnetic resonance spectroscopy investigations into the use of fructose to sustain hepatic ATP turnover during cold hypoxia in porcine livers. Cryobiology. 41 (1), pp. 72-87. https://doi.org/10.1006/cryo.2000.2268

Assessing gene expression in vivo: magnetic resonance imaging and spectroscopy
Bell, J.D. and Taylor-Robinson, S.D. 2000. Assessing gene expression in vivo: magnetic resonance imaging and spectroscopy. Gene Therapy. 7 (15), pp. 1259-1264.

Increased availability of central benzodiazepine receptors in patients with chronic hepatic encephalopathy and alcohol related cirrhosis
Jalan, R., Turjanski, N., Taylor-Robinson, S.D., Koepp, M.J., Richardson, M.P., Wilson, J.A., Bell, J.D. and Brooks, D.J. 2000. Increased availability of central benzodiazepine receptors in patients with chronic hepatic encephalopathy and alcohol related cirrhosis. Gut. 46 (4), pp. 546-552. https://doi.org/10.1136/gut.46.4.546

Cortical dysfunction in non-demented Parkinson's disease patients: A combined 31P-MRS and 18FDG-PET study
Hu, M.T.M., Taylor-Robinson, S.D., Chaudhuri, K.R., Bell, J.D., Labbé, C., Cunningham, V.J., Koepp, M.J., Hammers, A., Morris, R.G., Turjanski, N. and Brooks, D.J. 2000. Cortical dysfunction in non-demented Parkinson's disease patients: A combined 31P-MRS and 18FDG-PET study. Brain. 123 (2), pp. 340-352. https://doi.org/10.1093/brain/123.2.340

Wavelet estimation of a local long memory parameter
Whitcher, B. and Jensen, M.J. 2000. Wavelet estimation of a local long memory parameter. Exploration Geophysics. 31 (1-2), pp. 94-103. https://doi.org/10.1071/eg00094

Wavelet analysis of covariance with application to atmospheric time series
Whitcher, Brandon, Guttorp, P. and Percival, D.B. 2000. Wavelet analysis of covariance with application to atmospheric time series. Journal of Geophysical Research Atmospheres. 105 (D11), pp. 14941-14962 2000JD900110. https://doi.org/10.1029/2000JD900110

Multiscale detection and location of multiple variance changes in the presence of long memory
Whitcher, Brandon, Guttorp, P. and Percival, D.B. 2000. Multiscale detection and location of multiple variance changes in the presence of long memory. Journal of Statistical Computation and Simulation. 68 (1), pp. 65-87. https://doi.org/10.1080/00949650008812056

Preferential loss of visceral fat following aerobic exercise, measured by magnetic resonance imaging
Thomas, E.L., Brynes, A.E., McCarthy, J., Goldstone, A.P., Hajnal, J.V., Saeed, N., Frost, G.S. and Bell, J.D. 2000. Preferential loss of visceral fat following aerobic exercise, measured by magnetic resonance imaging. Lipids. 35 (7), pp. 769-776. https://doi.org/10.1007/s11745-000-0584-0

In vivo evaluation of the effects of continuous exercise on skeletal muscle triglycerides in trained humans
Rico-Sanz, J., Moosavi, M., Thomas, E.L., McCarthy, J., Coutts, G.A., Saeed, N. and Bell, J.D. 2000. In vivo evaluation of the effects of continuous exercise on skeletal muscle triglycerides in trained humans. Lipids. 35 (12), pp. 1313-1315. https://doi.org/10.1007/s11745-000-0647-2

Conflicting MRI signals from gliosis and neuronal vacuolation in prion diseases
Chung, Y.L., Williams, A., Ritchie, D., Williams, S.C.R., Changani, K.K., Hope, J. and Bell, J.D. 1999. Conflicting MRI signals from gliosis and neuronal vacuolation in prion diseases. NeuroReport. 10 (17), pp. 3471-3477.

Cerebral proton and phosphorus-31 magnetic resonance spectroscopy in patients with subclinical hepatic encephalopathy
Taylor-Robinson, S.D., Buckley, C., Changani, K.K., Hodgson, H.J.F. and Bell, J.D. 1999. Cerebral proton and phosphorus-31 magnetic resonance spectroscopy in patients with subclinical hepatic encephalopathy. Liver. 19 (5), pp. 389-398. https://doi.org/10.1111/j.1478-3231.1999.tb00067.x

Improved preservation solutions for organ storage: a dynamic study of hepatic metabolism
Changani, K.K., Fuller, B.J., Bell, J.D., Taylor-Robinson, S.D., Moore, D.P. and Davidson, B.R. 1999. Improved preservation solutions for organ storage: a dynamic study of hepatic metabolism. Transplantation. 68 (3), pp. 345-355.

Evidence for cortical dysfunction in clinically non-demented patients with Parkinson’s disease: a proton MR spectroscopy study
Hu, M.T.M., Taylor-Robinson, S.D., Chaudhuri, K.R., Bell, J.D., Morris, R.G., Clough, C., Brooks, D.J. and Turjanski, N. 1999. Evidence for cortical dysfunction in clinically non-demented patients with Parkinson’s disease: a proton MR spectroscopy study. Journal of Neurology, Neurosurgery, and Psychiatry. 67 (1), pp. 20-26. https://doi.org/10.1136/jnnp.67.1.20

Brain bioenergetics in murine models of scrapie using in vivo 31P magnetic resonance spectroscopy
Chung, Y.L., Williams, S.C.R., Hope, J. and Bell, J.D. 1999. Brain bioenergetics in murine models of scrapie using in vivo 31P magnetic resonance spectroscopy. NeuroReport. 10 (9), pp. 1899-1901.

Incorporation of metabolite prior knowledge for data analysis: biochemical implications of dynamic 31P NMR ex vivo pig liver studies
Changani, K.K., Ala-Korpela, M., Fuller, B.J., Mierisová, Ŝ., Bryant, D.J., Taylor-Robinson, S.D., Davidson, B.R. and Bell, J.D. 1999. Incorporation of metabolite prior knowledge for data analysis: biochemical implications of dynamic 31P NMR ex vivo pig liver studies. NMR in Biomedicine. 12 (4), pp. 197-204. https://doi.org/10.1002/(SICI)1099-1492(199906)12:4<197::AID-NBM561>3.0.CO;2-9

Relation between proton magnetic resonance spectroscopy within 18 hours of birth asphyxia and neurodevelopment at 1 year of age
Hanrahan, J.D., Cox, I.J., Azzopardi, D., Cowan, F.M., Sargentoni, J., Bell, J.D., Bryant, D.J. and Edwards, A.D. 1999. Relation between proton magnetic resonance spectroscopy within 18 hours of birth asphyxia and neurodevelopment at 1 year of age. Developmental Medicine & Child Neurology. 41 (2), pp. 76-82. https://doi.org/10.1111/j.1469-8749.1999.tb00558.x

A detailed analysis of neutral and acidic carbohydrates in human milk
Charlwood, J., Tolson, D., Dwek, M. and Camilleri, P. 1999. A detailed analysis of neutral and acidic carbohydrates in human milk. Analytical Biochemistry. 273 (2), pp. 261-277. https://doi.org/10.1006/abio.1999.4232

Body fat metabolism: observation by MR imaging and spectroscopy
Thomas, E.L. and Bell, J.D. 1999. Body fat metabolism: observation by MR imaging and spectroscopy. in: Young, I.R. (ed.) Magnetic resonance imaging and spectroscopy in medicine and biology Wiley.

Diversity in levels of intracellular total creatine and triglycerides in human skeletal muscles observed by 1H-MRS
Rico-Sanz, J., Thomas, E.L., Jenkinson, G., Mierisová, Ŝ., Iles, R.A. and Bell, J.D. 1999. Diversity in levels of intracellular total creatine and triglycerides in human skeletal muscles observed by 1H-MRS. Journal of Applied Physiology. 87 (6), pp. 2068-2072. https://doi.org/10.1152/jappl.1999.87.6.2068

Magnetic resonance: in-vivo NMR, applications – other nuclei
Bell, J.D., Thomas, E.L. and Changani, K.K. 1999. Magnetic resonance: in-vivo NMR, applications – other nuclei. in: Lindon, J. (ed.) Encyclopedia of spectroscopy and spectrometry London Academic Press.

Angiotensin-converting-enzyme gene insertion/deletion polymorphism and response to physical training
Montgomery, H., Clarkson, P., Barnard, M.L., Bell, J.D., Brynes, A.E., Hajnal, J.V., Hemingway, H., Mercer, D., Jarman, P., Marshall, R., Prasad, K., Rayson, M., Saeed, N., Thomas, E.L., Jubb, M., World, M., Dollery, C., Talmud, P. and Humphries, S.E. 1999. Angiotensin-converting-enzyme gene insertion/deletion polymorphism and response to physical training. The Lancet. 353 (9152), pp. 541-545. https://doi.org/10.1016/S0140-6736(98)07131-1

Relation of triglyceride stores in skeletal muscle cells to central obesity and insulin sensitivity in European and South Asian men
Forouhi, N.G., Jenkinson, G., Thomas, E.L., Mullick, S., Mierisová, Ŝ., Bhonsle, U., McKeigue, P.M. and Bell, J.D. 1999. Relation of triglyceride stores in skeletal muscle cells to central obesity and insulin sensitivity in European and South Asian men. Diabetologia. 42 (8), pp. 932-935. https://doi.org/10.1007/s001250051250

Metabolic changes underlying 31P MR spectral alterations in human hepatic tumours
Bell, J.D. and Bhakoo, K.K. 1998. Metabolic changes underlying 31P MR spectral alterations in human hepatic tumours. NMR in Biomedicine. 11 (7), pp. 354-359. https://doi.org/10.1002/(SICI)1099-1492(1998110)11:7<354::AID-NBM515>3.0.CO;2-N

Evaluation of the stability of the proton chemical shifts of some metabolites other than water during thermal cycling of normal human muscle tissue
Young, I.R., Bell, J.D., Hajnal, J.V., Jenkinson, G. and Ling, J. 1998. Evaluation of the stability of the proton chemical shifts of some metabolites other than water during thermal cycling of normal human muscle tissue. Journal of Magnetic Resonance Imaging. 8 (5), pp. 1114-1118. https://doi.org/10.1002/jmri.1880080517

Persistent increase in cerebral lactate concentration after birth asphyxia
Hanrahan, J.D., Cox, I.J., Edwards, A.D., Cowan, F.M., Sargentoni, J., Bell, J.D., Bryant, D.J., Rutherford, M.A. and Azzopardi, D. 1998. Persistent increase in cerebral lactate concentration after birth asphyxia. Pediatric Research. 44 (3), pp. 304-311. https://doi.org/10.1203/00006450-199809000-00007

Non-invasive metabolic assessment of human donor livers: metabolite assignment in 31P magnetic resonance spectroscopy
Changani, K.K., Taylor-Robinson, S.D., Bell, J.D., Fuller, B.J. and Davidson, B.R. 1998. Non-invasive metabolic assessment of human donor livers: metabolite assignment in 31P magnetic resonance spectroscopy. Transplantation. 65 (11), pp. 1526-1527.

13C-Glycogen deposition during pregnancy in the rat following routine meal feeding
Changani, K.K., Bell, J.D. and Iles, R.A. 1998. 13C-Glycogen deposition during pregnancy in the rat following routine meal feeding. Biochimica et Biophysica Acta: general subjects. 1380 (2), pp. 198-208. https://doi.org/10.1016/S0304-4165(97)00140-2

Breast cancer progression is associated with a reduction in the diversity of sialylated and neutral oligosaccharides.
Dwek, M.V., Lacey, H.A. and Leathem, A.J. 1998. Breast cancer progression is associated with a reduction in the diversity of sialylated and neutral oligosaccharides. Clinica Chimica Acta. 271 (2), pp. 191-202. https://doi.org/10.1016/s0009-8981(97)00258-1

Release and analysis of polypeptides and glycopolypeptides from formalin-fixed, paraffin wax-embedded tissue
Brooks, S.A., Dwek, M.V. and Leathem, A.J. 1998. Release and analysis of polypeptides and glycopolypeptides from formalin-fixed, paraffin wax-embedded tissue. The Histochemical journal. 30, pp. 609-615. https://doi.org/10.1023/a:1003222931605

In vivo and in vitro hepatic phosphorus-31 magnetic resonance spectroscopy and electron microscopy in chronic ductopenic rejection of human liver allografts
Taylor-Robinson, S.D., Sargentoni, J., Bell, J.D., Thomas, E.L., Marcus, C.D., Changani, K.K., Saeed, N., Hodgson, H., Davidson, B.R., Burroughs, A.K., Rolles, K., Foster, C.S. and Cox, I.J. 1998. In vivo and in vitro hepatic phosphorus-31 magnetic resonance spectroscopy and electron microscopy in chronic ductopenic rejection of human liver allografts. Gut. 42 (5), pp. 735-43. https://doi.org/10.1136/gut.42.5.735

Magnetic resonance imaging of total body fat
Thomas, E.L., Saeed, N., Hajnal, J.V., Brynes, A.E., Goldstone, A.P., Frost, G.S. and Bell, J.D. 1998. Magnetic resonance imaging of total body fat. Journal of Applied Physiology. 85 (5), pp. 1778-1785.

A comparison of ATP recovery or phosphomonoester/inorganic phosphate ratio to assess metabolic activity in liver at hypothermia: a 31P NMR study
Changani, K.K., Davidson, B.R., Bell, J.D., Taylor-Robinson, S.D. and Fuller, B.J. 1998. A comparison of ATP recovery or phosphomonoester/inorganic phosphate ratio to assess metabolic activity in liver at hypothermia: a 31P NMR study. CryoLetters. 19, pp. 183-188.

Enhanced energy metabolism at hypothermia following addition of a prostacyclin derivative in porcine liver
Changani, K.K., Davidson, B.R., Bell, J.D., Taylor-Robinson, S.D. and Fuller, B.J. 1998. Enhanced energy metabolism at hypothermia following addition of a prostacyclin derivative in porcine liver. CryoLetters. 19, pp. 131-140.

Depression of liver mitochondrial complex II-linked respiration following cooling: beneficial effects of using a prostacyclin analogue during hypothermia
Changani, K.K., Bell, J.D., Brooks, K.J., Fuller, B.J., Taylor-Robinson, S.D., Davidson, B.R., Brookes, P.S. and Bates, T.E. 1998. Depression of liver mitochondrial complex II-linked respiration following cooling: beneficial effects of using a prostacyclin analogue during hypothermia. CryoLetters. 19, pp. 71-78.

Human gene for physical performance
Montgomery, H., Marshall, R., Hemingway, H., Myerson, S., Clarkson, P., Dollery, C., Hayward, M., Holliman, D.E., Jubb, M., World, M., Thomas, E.L., Brynes, A.E., Saeed, N., Barnard, M.L., Bell, J.D., Prasad, K., Rayson, M., Talmud, P. and Humphries, S.E. 1998. Human gene for physical performance. Nature. 393 (6682), pp. 221-222. https://doi.org/10.1038/30374

Intracellular and extracellular skeletal muscle triglyceride metabolism during alternating intensity exercise in humans
Rico-Sanz, J., Hajnal, J.V., Thomas, E.L., Mierisová, Ŝ., Ala-Korpela, M. and Bell, J.D. 1998. Intracellular and extracellular skeletal muscle triglyceride metabolism during alternating intensity exercise in humans. Journal of Physiology. 510 (2), pp. 615-622. https://doi.org/10.1111/j.1469-7793.1998.615bk.x

Critical assessment of in vivo13C NMR spectroscopy and gas–liquid chromatography in the study of adipose tissue composition
Thomas, E.L., Cunnane, S.C. and Bell, J.D. 1998. Critical assessment of in vivo13C NMR spectroscopy and gas–liquid chromatography in the study of adipose tissue composition. NMR in Biomedicine. 11 (6), pp. 290-296. https://doi.org/10.1002/(SICI)1099-1492(199810)11:6<290::AID-NBM524>3.0.CO;2-N

Assessment of quantitative artificial neural network analysis in a metabolically dynamic ex vivo31p NMR pig liver study
Ala-Korpela, M., Changani, K.K., Hiltunen, Y., Bell, J.D., Fuller, B.J., Bryant, D.J., Taylor-Robinson, S.D. and Davidson, B.R. 1997. Assessment of quantitative artificial neural network analysis in a metabolically dynamic ex vivo31p NMR pig liver study. Magnetic Resonance in Medicine. 38 (5), pp. 840-844. https://doi.org/10.1002/mrm.1910380522

In vivo and in vitro hepatic 31P magnetic resonance spectroscopy and electron microscopy of the cirrhotic liver
Taylor-Robinson, S.D., Sargentoni, J., Bell, J.D., Saeed, N., Changani, K.K., Davidson, B.R., Rolles, K., Burroughs, A.K., Hodgson, H.J.F., Foster, C.S. and Cox, I.J. 1997. In vivo and in vitro hepatic 31P magnetic resonance spectroscopy and electron microscopy of the cirrhotic liver. Liver. 17 (4), pp. 198-209. https://doi.org/10.1111/j.1600-0676.1997.tb00806.x

Evidence for distinct behaviour of phosphatidylcholine and sphingomyelin at the low density lipoprotein surface
Murphy, H.C., Ala-Korpela, M., White, J.J., Raoof, A., Bell, J.D., Barnard, M.L., Burns, S.P. and Iles, R.A. 1997. Evidence for distinct behaviour of phosphatidylcholine and sphingomyelin at the low density lipoprotein surface. Biochemical and Biophysical Research Communications. 234 (3), pp. 733-737. https://doi.org/10.1006/bbrc.1997.6634

Non-invasive assessment of ATP regeneration potential of the preserved donor liver
Changani, K.K., Fuller, B.J., Bryant, D.J., Bell, J.D., Ala-Korpela, M., Taylor-Robinson, S.D., Moore, D.P. and Davidson, B.R. 1997. Non-invasive assessment of ATP regeneration potential of the preserved donor liver. Journal of Hepatology. 26 (2), pp. 336-342. https://doi.org/10.1016/S0168-8278(97)80050-5

The application of NMR spectroscopy to the study of apoptosis
Bhakoo, K.K. and Bell, J.D. 1997. The application of NMR spectroscopy to the study of apoptosis. Cellular and Molecular Biology. 43 (5), pp. 621-629.

Changes in adipose tissue composition in malnourished patients before and after liver transplantation: A carbon-13 magnetic resonance spectroscopy and gas-liquid chromatography study
Thomas, E.L., Taylor-Robinson, S.D., Barnard, M.L., Frost, G.S., Sargentoni, J., Davidson, B.R., Cunnane, S.C. and Bell, J.D. 1997. Changes in adipose tissue composition in malnourished patients before and after liver transplantation: A carbon-13 magnetic resonance spectroscopy and gas-liquid chromatography study. Hepatology. 25 (1), pp. 178-183. https://doi.org/10.1002/hep.510250133

Noninvasive characterization of neonatal adipose tissue by 13C magnetic resonance spectroscopy
Thomas, E.L., Hanrahan, J.D., Ala-Korpela, M., Jenkinson, G., Azzopardi, D., Iles, R.A. and Bell, J.D. 1997. Noninvasive characterization of neonatal adipose tissue by 13C magnetic resonance spectroscopy. Lipids. 32 (6), pp. 645-651. https://doi.org/10.1007/s11745-997-0082-4

In vivo assessment of metabolic perturbations following alanine and glucagon administration using 31P-MRS in the rat
Changani, K.K., Barnard, M.L., Bell, J.D., Thomas, E.L., Williams, S.C.R., Bloom, S.R. and Iles, R.A. 1997. In vivo assessment of metabolic perturbations following alanine and glucagon administration using 31P-MRS in the rat. Biochimica et Biophysica Acta: general subjects. 1335 (3), pp. 290-304. https://doi.org/10.1016/S0304-4165(96)00148-1

Metabolic changes associated with vacuolation in murine models of scrapie using in vitro 1H-NMR spectroscopy
Chung, Y.L., Williams, A., Chong, A., Hope, J., Williams, S.C.R. and Bell, J.D. 1996. Metabolic changes associated with vacuolation in murine models of scrapie using in vitro 1H-NMR spectroscopy. NMR in Biomedicine. 9 (8), pp. 359-363. https://doi.org/10.1002/(SICI)1099-1492(199612)9:8<359::AID-NBM428>3.0.CO;2-D

Hepatic nucleotide triphosphate regeneration following a period of brief hypothermic reperfusion in the pig model: an in vitro 31P-NMR study
Changani, K.K., Fuller, B.J., Bell, J.D., Bryant, D.J., Moore, D.P., Taylor-Robinson, S.D. and Davidson, B.R. 1996. Hepatic nucleotide triphosphate regeneration following a period of brief hypothermic reperfusion in the pig model: an in vitro 31P-NMR study. Transplantation. 62 (6), pp. 787-793.

Characterisation of secondary metabolites associated with neutrophil apoptosis
Nunn, A.V.W., Barnard, M.L., Bhakoo, K.K., Murray, J., Chilvers, E.J. and Bell, J.D. 1996. Characterisation of secondary metabolites associated with neutrophil apoptosis. FEBS Letters. 392 (3), pp. 295-298. https://doi.org/10.1016/0014-5793(96)00839-3

Cerebral metabolism within 18 hours of birth asphyxia: a proton magnetic resonance spectroscopy study
Hanrahan, J.D., Sargentoni, J., Azzopardi, D., Manji, K., Cowan, F.M., Rutherford, M.A., Cox, I.J., Bell, J.D., Bryant, D.J. and Edwards, A.D. 1996. Cerebral metabolism within 18 hours of birth asphyxia: a proton magnetic resonance spectroscopy study. Paediatric Research. 39 (4), pp. 584-590. https://doi.org/10.1203/00006450-199604000-00004

Identification, purification and analysis of a 55 kDa lectin binding glycoprotein present in breast cancer tissue.
Streets, A.J., Brooks, S.A., Dwek, M.V. and Leathem, A.J. 1996. Identification, purification and analysis of a 55 kDa lectin binding glycoprotein present in breast cancer tissue. Clinica Chimica Acta. 254 (1), pp. 47-61. https://doi.org/10.1016/0009-8981(96)06363-2

Oligosaccharide release from frozen and paraffin-wax-embedded archival tissues.
Dwek, M.V., Brooks, S.A., Streets, A.J., Harvey, D.J. and Leathem, A.J. 1996. Oligosaccharide release from frozen and paraffin-wax-embedded archival tissues. Analytical Biochemistry. 242 (1), pp. 8-14. https://doi.org/10.1006/abio.1996.0420

Hepatic phosphorus-31 magnetic resonance spectroscopy in primary biliary cirrhosis and its relation to prognostic models
Jalan, R., Sargentoni, J., Coutts, G.A., Bell, J.D., Rolles, K., Burroughs, A.K. and Taylor-Robinson, S.D. 1996. Hepatic phosphorus-31 magnetic resonance spectroscopy in primary biliary cirrhosis and its relation to prognostic models. Gut. 39 (1), pp. 141-146. https://doi.org/10.1136/gut.39.1.141

Body fluid spectroscopic studies
Bell, J.D. and Sadler, P.J. 1996. Body fluid spectroscopic studies. in: Grant, D.M. and Harris, R.K. (ed.) Encyclopedia of nuclear magnetic resonance Chichester Wiley.

Dietary changes: observation by NMR spectroscopy
Bell, J.D. and Barnard, M.L. 1996. Dietary changes: observation by NMR spectroscopy. in: Grant, D.M. and Harris, R.K. (ed.) Encyclopedia of nuclear magnetic resonance Chichester Wiley.

Artificial neural network analysis of 1H NMR spectroscopic data from human plasma
Ala-Korpela, M., Hiltunen, Y. and Bell, J.D. 1996. Artificial neural network analysis of 1H NMR spectroscopic data from human plasma. Anticancer Research. 16 (3B), pp. 1473-1478.

An in vivo 13C magnetic resonance spectroscopic study of the relationship between diet and adipose tissue composition
Thomas, E.L., Frost, G.S., Barnard, M.L., Bryant, D.J., Taylor-Robinson, S.D., Simbrunner, J., Coutts, G.A., Burl, M., Bloom, S.R., Sales, K.D. and Bell, J.D. 1996. An in vivo 13C magnetic resonance spectroscopic study of the relationship between diet and adipose tissue composition. Lipids. 31 (2), pp. 145-151. https://doi.org/10.1007/BF02522613

Automated feature extraction for the classification of human in vivo13C NMR spectra using statistical pattern recognition and wavelets
Tate, A.R., Watson, D., Eglen, S., Arvanitis, T.N., Thomas, E.L. and Bell, J.D. 1996. Automated feature extraction for the classification of human in vivo13C NMR spectra using statistical pattern recognition and wavelets. Magnetic Resonance in Medicine. 35 (6), pp. 834-840. https://doi.org/10.1002/mrm.1910350608

Development of a rapid and efficient magnetic resonance imaging technique for analysis of body fat distribution
Barnard, M.L., Schwieso, J.E., Thomas, E.L., Bell, J.D., Saeed, N., Frost, G.S., Bloom, S.R. and Hajnal, J.V. 1996. Development of a rapid and efficient magnetic resonance imaging technique for analysis of body fat distribution. NMR in Biomedicine. 9 (4), pp. 156-164. https://doi.org/10.1002/(SICI)1099-1492(199606)9:4<156::AID-NBM412>3.0.CO;2-B

Effects of n-3 fatty acids on the NMR profile of plasma lipoproteins
Bell, J.D., Barnard, M.L., Parkes, H.G., Thomas, E.L., Brennan, C.H., Cunnane, S.C. and Dagnelie, P.C. 1996. Effects of n-3 fatty acids on the NMR profile of plasma lipoproteins. The Journal of Lipid Research. 37 (8), pp. 1664-1674.

Cirrhosis of the human liver: an in vitro 31P nuclear magnetic resonance study
Taylor-Robinson, S.D., Thomas, E.L., Sargentoni, J., Marcus, C.D., Davidson, B.R. and Bell, J.D. 1995. Cirrhosis of the human liver: an in vitro 31P nuclear magnetic resonance study. Biochimica et Biophysica Acta: Molecular Basis of Disease. 1272 (2), pp. 113-118. https://doi.org/10.1016/0925-4439(95)00074-E

Quantification of biomedical NMR data using artificial neural network analysis: lipoprotein lipid profiles from 1H NMR data of human plasma
Ala-Korpela, M., Hiltunen, Y. and Bell, J.D. 1995. Quantification of biomedical NMR data using artificial neural network analysis: lipoprotein lipid profiles from 1H NMR data of human plasma. NMR in Biomedicine. 8 (6), pp. 235-244. https://doi.org/10.1002/nbm.1940080603

MRI assessment of the blood-brain barrier in a hamster model of scrapie
Chung, Y.L., Williams, A., Beech, J.S., Williams, S.C.R., Bell, J.D., Cox, I.J. and Hope, J. 1995. MRI assessment of the blood-brain barrier in a hamster model of scrapie. Neurodegeneration. 4 (2), pp. 203-207. https://doi.org/10.1006/neur.1995.0025

Effect of functional grade and etiology on in vivo hepatic phosphorus-31 magnetic resonance spectroscopy in cirrhosis: Biochemical basis of spectral appearances
Menon, D.K., Sargentoni, J., Taylor-Robinson, S.D., Bell, J.D., Cox, I.J., Bryant, D.J., Coutts, G.A., Rolles, K., Burroughs, A.K. and Morgan, M.Y. 1995. Effect of functional grade and etiology on in vivo hepatic phosphorus-31 magnetic resonance spectroscopy in cirrhosis: Biochemical basis of spectral appearances. Hepatology. 21 (2), pp. 417-427. https://doi.org/10.1002/hep.1840210224

Cerebral 31P MRS in patients with chronic hepatic encephalopathy
Taylor-Robinson, S.D., Bell, J.D., Sargentoni, J., Bryant, D.J., Mallalieu, R.J. and Morgan, M.Y. 1995. Cerebral 31P MRS in patients with chronic hepatic encephalopathy. in: Capocaccia, L., Merli, M. and Riggio, O. (ed.) Advances in hepatic encephalopathy and metabolic nitrogen exchange Hants CRC Press.

Cerebral Phosphorus-31 magnetic resonance spectroscopy in patients with chronic hepatic encephalopathy
Taylor-Robinson, S.D., Sargentoni, J., Mallalieu, R.J., Bell, J.D., Bryant, D.J., Coutts, G.A. and Morgan, M.Y. 1994. Cerebral Phosphorus-31 magnetic resonance spectroscopy in patients with chronic hepatic encephalopathy. Hepatology. 20 (5), pp. 1173-1178. https://doi.org/10.1002/hep.1840200511

Utilization of uniformly labeled 13C-polyunsaturated fatty acids in the synthesis of long-chain fatty acids and cholesterol accumulating in the neonatal rat brain
Cunnane, S.C., Williams, S.C.R., Bell, J.D., Brookes, S., Craig, K., Iles, R.A. and Crawford, M.A. 1994. Utilization of uniformly labeled 13C-polyunsaturated fatty acids in the synthesis of long-chain fatty acids and cholesterol accumulating in the neonatal rat brain. Journal of Neurochemistry. 62 (6), pp. 2429-2436. https://doi.org/10.1046/j.1471-4159.1994.62062429.x

Effect of fish oil on cancer cachexia and host liver metabolism in rats with prostate tumours
Dagnelie, P.C., Bell, J.D., Williams, S.C.R., Bates, T.E., Abel, P.D. and Foster, C.S. 1994. Effect of fish oil on cancer cachexia and host liver metabolism in rats with prostate tumours. Lipids. 29 (3), pp. 195-203. https://doi.org/10.1007/BF02536729

Altered expression of N-acetyl galactosamine glycoproteins by breast cancers.
Brooks, S.A., Leathem, A.J. and Dwek, M.V. 1994. Altered expression of N-acetyl galactosamine glycoproteins by breast cancers. Biochemical Society Transactions. 22 (2), p. 95S. https://doi.org/10.1042/bst022095s

NMR studies of body fluids and tissue extracts
Bell, J.D., Preece, N.E. and Parkes, H.G. 1994. NMR studies of body fluids and tissue extracts. in: Gillies, R. (ed.) Nuclear magnetic resonance in physiology and biomedicine Oxford Pergamon.

In vivo fluorine-19 magnetic resonance spectroscopy of cerebral halothane in postoperative patients: preliminary results
Menon, D.K., Lockwood, G.G., Peden, C.J., Cox, I.J., Sargentoni, J., Bell, J.D., Coutts, G.A. and Whitwam, J.G. 1993. In vivo fluorine-19 magnetic resonance spectroscopy of cerebral halothane in postoperative patients: preliminary results. Magnetic Resonance in Medicine. 30 (6), pp. 680-684. https://doi.org/10.1002/mrm.1910300605

A 31P and 1H NMR investigation in vitro of normal and abnormal human liver
Bell, J.D., Cox, I.J., Sargentoni, J., Peden, C.J., Menon, D.K., Foster, C.S., Watanapa, P., Iles, R.A. and Urenjak, J. 1993. A 31P and 1H NMR investigation in vitro of normal and abnormal human liver. Biochimica et Biophysica Acta: Lipids and Lipid Metabolism. 1225 (1), pp. 71-77.

Altered phosphorylation status, phospholipid metabolism and gluconeogenesis in the host liver of rats with prostate cancer: a 31P magnetic resonance spectroscopy study
Dagnelie, P.C., Bell, J.D., Williams, S.C.R., Bates, T.E., Abel, P.D. and Foster, C.S. 1993. Altered phosphorylation status, phospholipid metabolism and gluconeogenesis in the host liver of rats with prostate cancer: a 31P magnetic resonance spectroscopy study. British Journal of Cancer. 67 (6), pp. 1303-1309. https://doi.org/10.1038/bjc.1993.242

The proton NMR spectrum in acute EAE: the significance of the change in the Cho:Cr ratio
Brenner, R.E., Munro, P.M.G., Williams, S.C.R., Bell, J.D., Barker, G.J., Landon, D.N., Hawkins, C.P. and McDonald, W.I. 1993. The proton NMR spectrum in acute EAE: the significance of the change in the Cho:Cr ratio. Magnetic Resonance in Medicine. 29 (6), pp. 737-745. https://doi.org/10.1002/mrm.1910290605

Effects of fish oil on phospholipid metabolism in human and rat liver studied by 31P NMR spectroscopy in vivo and in vitro
Dagnelie, P.C., Bell, J.D., Cox, I.J., Menon, D.K., Sargentoni, J., Coutts, G.A. and Williams, S.C.R. 1993. Effects of fish oil on phospholipid metabolism in human and rat liver studied by 31P NMR spectroscopy in vivo and in vitro. NMR in Biomedicine. 6 (2), pp. 157-162. https://doi.org/10.1002/nbm.1940060209

Potential of nuclear magnetic resonance spectroscopy for studies of N- fatty acid metabolism in plasma, liver and adipose tissues
Dagnelie, P.C., Bell, J.D., Barnard, M.L. and Williams, S.C.R. 1993. Potential of nuclear magnetic resonance spectroscopy for studies of N- fatty acid metabolism in plasma, liver and adipose tissues. in: Drevon, A., Baksaas, I. and Krokan, H.E. (ed.) Omega-3 fatty acids: metabolism and biological effects Basel, Switzerland Birkhauser Verlag. pp. 27-34

In vivo fatty acid analysis in humans and animals using carbon-13 nuclear magnetic resonance spectroscopy
Cunnane, S.C., Allman, T., Bell, J.D., Barnard, M.L., Coutts, G.A., Williams, S.C.R. and Iles, R.A. 1993. In vivo fatty acid analysis in humans and animals using carbon-13 nuclear magnetic resonance spectroscopy. Basic Life Sciences. 60, pp. 355-358. https://doi.org/10.1007/978-1-4899-1268-8_83

NMR: a clinical approach
Bell, J.D. and Sadler, P.J. 1993. NMR: a clinical approach. Chemistry in Britain. 29, pp. 597-600.

Detection of aluminium (III) binding to citrate in human blood plasma by proton nuclear magnetic resonance spectroscopy
Bell, J.D., Kubal, G., Radulovic, S., Sadler, P.J. and Tucker, A. 1993. Detection of aluminium (III) binding to citrate in human blood plasma by proton nuclear magnetic resonance spectroscopy. The Analyst. 118, pp. 241-244. https://doi.org/10.1039/AN9931800241

Phosphorus-31 magnetic resonance spectroscopy of the human liver using chemical shift imaging techniques
Cox, I.J., Menon, D.K., Sargentoni, J., Bryant, D.J., Collins, A.G., Coutts, G.A., Iles, R.A., Bell, J.D., Benjamin, I.S., Gilbey, S., Hodgson, H.J.F. and Morgan, M.Y. 1992. Phosphorus-31 magnetic resonance spectroscopy of the human liver using chemical shift imaging techniques. Journal of Hepatology. 14 (2-3), pp. 265-275. https://doi.org/10.1016/0168-8278(92)90169-P

Effect of l-alanine infusion on 31P nuclear magnetic resonance spectra of normal human liver: towards biochemical pathology in vivo
Dagnelie, P.C., Menon, D.K., Cox, I.J., Bell, J.D., Sargentoni, J., Coutts, G.A., Urenjak, J. and Iles, R.A. 1992. Effect of l-alanine infusion on 31P nuclear magnetic resonance spectra of normal human liver: towards biochemical pathology in vivo. Clinical Science: an international journal of translational science and medicine. 83, pp. 183-190. https://doi.org/10.1042/cs0830183

In vivo and in vitro31P magnetic resonance spectroscopy of focal hepatic malignancies
Cox, I.J., Bell, J.D., Peden, C.J., Iles, R.A., Foster, C.S., Watanapa, P. and Williamson, R.C.N. 1992. In vivo and in vitro31P magnetic resonance spectroscopy of focal hepatic malignancies. NMR in Biomedicine. 5 (3), pp. 114-120. https://doi.org/10.1002/nbm.1940050303

MRS characterisation of tissue and body fluids
Bell, J.D. 1992. MRS characterisation of tissue and body fluids. in: Textbook of magnetic resonance spectroscopy in biology and medicine: functional and pathological tissue characterisation Oxford Pergamon.

In vivo detection of metabolic changes in a mouse model of scrapie using nuclear magnetic resonance spectroscopy
Bell, J.D., Cox, I.J., Williams, S.C.R., Belton, P.S., McConnell, I. and Hope, J. 1991. In vivo detection of metabolic changes in a mouse model of scrapie using nuclear magnetic resonance spectroscopy. Journal of General Virology. 72 (10), pp. 2419-2423. https://doi.org/10.1099/0022-1317-72-10-2419

Aluminium speciation: NMR studies of blood plasma, transferrin and citrate complexes
Bell, J.D., Evans, R.W., Kiang, W., Kubal, G., Radulovic, S., Sadler, P.J. and Williams, G. 1991. Aluminium speciation: NMR studies of blood plasma, transferrin and citrate complexes. Journal of Inorganic Biochemistry. 43 (2-3), p. 488. https://doi.org/10.1016/0162-0134(91)84467-N

Metabolites in the developing rat liver: a proton nuclear magnetic resonance spectroscopic study
Rafter, J.E.M., Bates, T.E., Bell, J.D. and Iles, R.A. 1991. Metabolites in the developing rat liver: a proton nuclear magnetic resonance spectroscopic study. Biochimica et Biophysica Acta: general subjects. 1074 (2), pp. 263-269. https://doi.org/10.1016/0304-4165(91)90162-A

Approaches to editing, assignment and interpretation of proton spectra
Gadian, D.G., Bates, T.E., Williams, S.R., Bell, J.D., Austin, S.J. and Connelly, A. 1991. Approaches to editing, assignment and interpretation of proton spectra. NMR in Biomedicine. 4 (2), pp. 85-89. https://doi.org/10.1002/nbm.1940040210

Nuclear magnetic resonance studies of blood plasma and urine from subjects with chronic renal failure: identification of trimethylamine-N-oxide
Bell, J.D., Lee, J.D., Lee, H.A., Sadler, P.J., Wilkie, D.R. and Woodham, R.H. 1991. Nuclear magnetic resonance studies of blood plasma and urine from subjects with chronic renal failure: identification of trimethylamine-N-oxide. Biochimica et Biophysica Acta: general subjects. 1096 (2), pp. 101-107. https://doi.org/10.1016/0925-4439(91)90046-C

Proton magnetic resonance spectroscopy in chronic renal failure
Menon, D.K., Cassidy, M.J.D., Baudouin, C., Sandford, R.N., Bell, J.D. and Sargentoni, J. 1991. Proton magnetic resonance spectroscopy in chronic renal failure. The Lancet. 337 (8735), pp. 244-245. https://doi.org/10.1016/0140-6736(91)92217-P

Proton MR spectroscopy in herpes simplex encephalitis: assessment of neuronal loss
Menon, D.K., Sargentoni, J., Peden, C.J., Bell, J.D., Cox, I.J., Coutts, G.A., Baudouin, C. and Newman, C.G.H. 1990. Proton MR spectroscopy in herpes simplex encephalitis: assessment of neuronal loss. Journal of Computer Assisted Tomography. 14 (3), pp. 449-452.

31P Magnetic resonance spectroscopy of the human paediatric liver
Iles, R.A., Cox, I.J., Bell, J.D., Dubowitz, L.M.S., Cowan, F.M. and Bryant, D.J. 1990. 31P Magnetic resonance spectroscopy of the human paediatric liver. NMR in Biomedicine. 3 (2), pp. 90-94. https://doi.org/10.1002/nbm.1940030207

NMR studies of drug metabolism and disposition
Bell, J.D., Gadian, D.G. and Preece, N.E. 1990. NMR studies of drug metabolism and disposition. European Journal of Drug Metabolism and Pharmacokinetics. 15 (2), pp. 127-133. https://doi.org/10.1007/BF03190195

Proton MR spectroscopy of the brain in infants
Peden, C.J., Cowan, F.M., Bryant, D.J., Sargentoni, J., Cox, I.J., Menon, D.K., Gadian, D.G., Bell, J.D. and Dubowitz, L.M.S. 1990. Proton MR spectroscopy of the brain in infants. Journal of Computer Assisted Tomography. 14 (6), pp. 886-894.

Proton MR spectroscopy of intracranial tumours: in vivo and in vitro studies
Gill, S.S., Thomas, D.G.T., van Bruggen, N., Gadian, D.G., Peden, C.J., Bell, J.D., Cox, I.J., Menon, D.K., Iles, R.A., Bryant, D.J. and Coutts, G.A. 1990. Proton MR spectroscopy of intracranial tumours: in vivo and in vitro studies. Journal of Computer Assisted Tomography. 14 (4), pp. 497-502.

NMR studies of body fluids
Bell, J.D., Brown, J.C.C. and Sadler, P.J. 1989. NMR studies of body fluids. NMR in Biomedicine. 2 (5-6), pp. 246-256. https://doi.org/10.1002/nbm.1940020513

1H NMR study of cerebral development in the rat
Bates, T.E., Williams, S.R., Gadian, D.G., Bell, J.D., Small, R.K. and Iles, R.A. 1989. 1H NMR study of cerebral development in the rat. NMR in Biomedicine. 2 (5-6), pp. 225-229. https://doi.org/10.1002/nbm.1940020509

Non-transferrin-bound iron in plasma or serum from patients with idiopathic hemochromatosis. Characterization by high performance liquid chromatography and nuclear magnetic resonance spectroscopy
Grootveld, M., Bell, J.D., Halliwell, B., Aruoma, O.I., Bomford, A. and Sadler, P.J. 1989. Non-transferrin-bound iron in plasma or serum from patients with idiopathic hemochromatosis. Characterization by high performance liquid chromatography and nuclear magnetic resonance spectroscopy. Journal of Biological Chemistry. 264 (8), pp. 4417-4422.

Nuclear magnetic resonance studies of body fluids: an overview
Bell, J.D. 1989. Nuclear magnetic resonance studies of body fluids: an overview. in: de Certaines, J.D. (ed.) Magnetic resonance spectroscopy of biofluids: a new tool in clinical biology London, U.K. World Scientific Publishing.

NMR-invisible lactate in blood plasma
Bell, J.D., Brown, J.C.C., Kubal, G. and Sadler, P.J. 1988. NMR-invisible lactate in blood plasma. FEBS Letters. 235 (1-2), pp. 81-86. https://doi.org/10.1016/0014-5793(88)81238-9

Factors affecting 1h NMR spectra of blood plasma: cancer, diet and freezing
Bell, J.D., Brown, J.C.C., Norman, R.E., Sadler, P.J. and Newell, D.R. 1988. Factors affecting 1h NMR spectra of blood plasma: cancer, diet and freezing. NMR in Biomedicine. 1 (2), pp. 90-94. https://doi.org/10.1002/nbm.1940010206

Metabolic profiling of body fluids by proton NMR: self-poisoning episodes with paracetamol (acetaminophen)
Bales, J.R., Bell, J.D., Nicholson, J.K., Sadler, P.J., Timbrell, J.A., Hughes, R.D., Bennett, P.N. and Williams, R. 1988. Metabolic profiling of body fluids by proton NMR: self-poisoning episodes with paracetamol (acetaminophen). Magnetic Resonance in Medicine. 6 (3), pp. 300-306. https://doi.org/10.1002/mrm.1910060308

NMR Spectroscopy of body fluids
Bell, J.D., Brown, J.C.C. and Sadler, P.J. 1988. NMR Spectroscopy of body fluids. Chemistry in Britain. 24, pp. 1021-1024.

Coordination chemistry in biological media: reactions of antitumor Pt(II) and Au(III) complexes with cell culture media
Bell, J.D., Norman, R.E. and Sadler, P.J. 1987. Coordination chemistry in biological media: reactions of antitumor Pt(II) and Au(III) complexes with cell culture media. Journal of Inorganic Biochemistry. 31 (4), pp. 241-246. https://doi.org/10.1016/0162-0134(87)80078-8

1H NMR studies of human blood plasma assignment of resonances for lipoproteins
Bell, J.D., Sadler, P.J., MacLeod, A.F., Turner, P.R. and La Ville, A. 1987. 1H NMR studies of human blood plasma assignment of resonances for lipoproteins. FEBS Letters. 219 (1), pp. 239-243. https://doi.org/10.1016/0014-5793(87)81224-3

Assignment of resonances for ‘acute-phase’ glycoproteins in high resolution proton NMR spectra of human blood plasma
Bell, J.D., Brown, J.C.C., Nicholson, J.K. and Sadler, P.J. 1987. Assignment of resonances for ‘acute-phase’ glycoproteins in high resolution proton NMR spectra of human blood plasma. FEBS Letters. 215 (2), pp. 311-315. https://doi.org/10.1016/0014-5793(87)80168-0

High resolution proton nuclear magnetic resonance studies of human cerebrospinal fluid
Bell, J.D., Brown, J.C.C., Sadler, P.J., MacLeod, A.F., Sönksen, P.H., Hughes, R.D. and Williams, R. 1987. High resolution proton nuclear magnetic resonance studies of human cerebrospinal fluid. Clinical Science: an international journal of translational science and medicine. 72, pp. 563-570. https://doi.org/10.1042/cs0720563

1H NMR studies of urine during fasting: excretion of ketone bodies and acetylcarnitine
Bales, J.R., Bell, J.D., Nicholson, J.K. and Sadler, P.J. 1986. 1H NMR studies of urine during fasting: excretion of ketone bodies and acetylcarnitine. Magnetic Resonance in Medicine. 3 (6), pp. 849-856. https://doi.org/10.1002/mrm.1910030605

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