Title | Proton MR spectroscopy in herpes simplex encephalitis: assessment of neuronal loss |
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Authors | Menon, D.K., Sargentoni, J., Peden, C.J., Bell, J.D., Cox, I.J., Coutts, G.A., Baudouin, C. and Newman, C.G.H. |
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Abstract | We present here the case of an 11-year-old boy with herpes simplex encephalitis diagnosed on the basis of clinical features, serology, and response to acyclovir, who relapsed after 3 weeks of therapy. In vivo proton magnetic resonance spectroscopy (1H MRS) of the brain, at 8 and 16 weeks after the onset of symptoms, showed abnormalities, most prominently a reduction in the N-acetylaspartate/choline ratio. The role of 1H-MRS in assessing disease activity is discussed. |
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Journal | Journal of Computer Assisted Tomography |
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Journal citation | 14 (3), pp. 449-452 |
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ISSN | 1532-3145 |
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Year | May 1990 |
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Publisher | Lippincott Williams & Wilkins |
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Web address (URL) | http://journals.lww.com/jcat/Abstract/1990/05000/Proton_MR_Spectroscopy_in_Herpes_Simplex.24.aspx |
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Publication dates |
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Published | May 1990 |
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