Abstract | Neurological diseases impose substantial socioeconomic burden on the society. These diseases are characterized by damage to specific populations of cells within specific areas of the nervous system. The extremely high metabolic demands of neuronal tissue result in high oxygen consumption and energy production. Neurological tissue is particularly high risk of oxidative damage from reactive oxygen species. As a result, oxidative stress has implicated in the pathogenesis of several neurodegenerative diseases including Alzheimer's and Parkinson’s. Antioxidant compounds that inhibit oxidation are required to prevent oxidative damage in vivo. Oxidative stress reflects an imbalance between the systemic manifestation of ROS and the ability to detoxify the ROS or repair the resulting damage. In the 1920s and 1930s, the isolation of vitamins C and E and their identification as dietary antioxidants revolutionized the field. Since then the knowledge and understanding of oxidative stress and antioxidants has increased exponentially. It is now difficult even for experienced scientists to remain up to date. To assist colleagues who are interested in understanding more about this field, we have, therefore, produced tables containing up-to-date resources on the regulatory and professional bodies, journals, books, and websites that are relevant to the study of oxidative stress and dietary antioxidants in neurological disease. |
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