HFE mRNA expression is responsive to intracellular and extracellular iron loading: short communication

Antioxidant and Antidiabetic Properties of a Thinned-Nectarine-Based Nanoformulation in a Pancreatic β-Cell Line
Elisabetta Schiano, Ettore Novellino, Marta María Gámez Fernández, Helena Tiekou Lorinczova, Gian Carlo Tenore, Fortuna Iannuzzo, Vinood B. Patel, Satyanarayana Somavarapu and Mohammed Gulrez Zariwala 2023. Antioxidant and Antidiabetic Properties of a Thinned-Nectarine-Based Nanoformulation in a Pancreatic β-Cell Line. Antioxidants. 13 (1) 63. https://doi.org/10.3390/antiox13010063

Baseline and recurrent exposure to the standard dose of artemisinin-based combination therapies (ACTs) induces oxidative stress and liver damage in mice (BALB/c)
Audu, D., Patel, V.B., Idowu, O.A., Mshelbwala, F.M. and Idowu, A.B. 2023. Baseline and recurrent exposure to the standard dose of artemisinin-based combination therapies (ACTs) induces oxidative stress and liver damage in mice (BALB/c). Egyptian Liver Journal. 13 53. https://doi.org/10.1186/s43066-023-00291-7

Non-alcoholic fatty liver disease: Immunological mechanisms and current treatments.
Petagine, Lucy, Zariwala, Mohammed Gulrez and Patel, Vinood B 2023. Non-alcoholic fatty liver disease: Immunological mechanisms and current treatments. World Journal of Gastroenterology. 29 (32), pp. 4831-4850. https://doi.org/10.3748/wjg.v29.i32.4831

Time-Dependent Alterations in Liver Oxidative Stress due to Ethanol and Acetaldehyde
Petagine, L., Everitt, H.E., Sherwood, R., Gyamfi, D. and Patel, V.B. 2022. Time-Dependent Alterations in Liver Oxidative Stress due to Ethanol and Acetaldehyde. Journal of Renal and Hepatic Disorders. 6 (1), pp. 56-66. https://doi.org/10.15586/jrenhep.v6i1.143

Excessive Iron Induces Oxidative Stress Promoting Cellular Perturbations and Insulin Secretory Dysfunction in MIN6 Beta Cells.
Blesia, V., Patel, V.B., Al-Obaidi, H., Renshaw, D. and Zariwala, M. 2021. Excessive Iron Induces Oxidative Stress Promoting Cellular Perturbations and Insulin Secretory Dysfunction in MIN6 Beta Cells. Cells. 10 (5) 1141. https://doi.org/10.3390/cells10051141

Research and recommended resources on Zika virus, pathology, and control
Rajendram, R., Preedy, V.R. and Patel, V. 2021. Research and recommended resources on Zika virus, pathology, and control. in: Martin, C.R., Hollins Martin, C.J., Preedy, V.R. and Rajendram, R. (ed.) Zika Virus Biology, Transmission, and Pathology. Volume 1: The Neuroscience of Zika Academic Press. pp. 479-491

Acute Alcohol Tissue Damage: Protective Properties of Betaine
Petagine, L., Everitt, H.E., Preedy, V.R., Sherwood, R. and Patel, V.B. 2021. Acute Alcohol Tissue Damage: Protective Properties of Betaine. Journal of Renal and Hepatic Disorders. 5 (1), pp. 19-29. https://doi.org/10.15586/jrenhep.v5i1.96

Recommended resources on the neuroscience of depression: Genetics, cell biology, neurology, behavior, and diet
Rajendram, R., Patel, V. and Preedy, V.R. 2021. Recommended resources on the neuroscience of depression: Genetics, cell biology, neurology, behavior, and diet. in: Martin, C.R., Hunter, L.A., Patel, V., Preedy, V.R. and Rajendram, R. (ed.) The Neuroscience of Depression: Genetics, Cell Biology, Neurology, Behaviour, and Diet Academic Press. pp. 531-537

Recommended resources for oxidative stress and dietary antioxidants in neurological diseases
Rajendram, R., Patel, V. and Preedy, V.R. 2020. Recommended resources for oxidative stress and dietary antioxidants in neurological diseases. in: Martin, C.R. and Preedy, V.R. (ed.) Oxidative Stress and Dietary Antioxidants in Neurological Diseases Academic Press. pp. 393-397

Hepcidin secretion was not directly proportional to intracellular iron-loading in recombinant-TfR1 HepG2 cells: short communication
Mehta, K., Busbridge Mark, Patel, V.B. and Farnaud, S. 2020. Hepcidin secretion was not directly proportional to intracellular iron-loading in recombinant-TfR1 HepG2 cells: short communication. Molecular and Cellular Biochemistry. 468 (1-2), pp. 121-128. https://doi.org/10.1007/s11010-020-03716-8

High omega arachidonic acid/docosahexaenoic acid ratio induces mitochondrial dysfunction and altered lipid metabolism in human hepatoma cells
Ghazali, R., Mehta, K., Bligh, S.W.A., Tewfik, I., Clemens, D.L. and Patel, V.B. 2020. High omega arachidonic acid/docosahexaenoic acid ratio induces mitochondrial dysfunction and altered lipid metabolism in human hepatoma cells. World Journal of Hepatology. 12 (3), pp. 84-98. https://doi.org/10.4254/wjh.v12.i3.84

Measurement of 4-Hydroxynonenal (4-HNE) Protein Adducts by ELISA
Mehta, K. and Patel, V.B. 2019. Measurement of 4-Hydroxynonenal (4-HNE) Protein Adducts by ELISA. in: Hancock, J. and Conway, M.E. (ed.) Redox mediated Siganl Transduction. Methods in Molecular Biology New York Humana Press.

Excessive iron accumulation induces beta cell cellular oxidative stress and insulin secretory dysfunction in MIN6 cells
Blesia, V., Patel, V., Al‐Obaidi, H. and Zariwala, M. 2019. Excessive iron accumulation induces beta cell cellular oxidative stress and insulin secretory dysfunction in MIN6 cells. Diabetes UK Professional Conference 2019. Liverpool 06 - 08 Mar 2019 Wiley. https://doi.org/10.1111/dme.2_13883

Hydrophobically modified chitosan nanoliposomes for intestinal drug delivery
Zariwala, M., Bendre, H., Markiv, A., Farnaud, S., Renshaw, D., Taylor, K.M.G. and Somavarapu, S. 2018. Hydrophobically modified chitosan nanoliposomes for intestinal drug delivery. International Journal of Nanomedicine. 13, pp. 5837-5848. https://doi.org/10.2147/IJN.S166901

Mucosa-associated invariant T cells link intestinal immunity with antibacterial immune defects in alcoholic liver disease
Riva, A., Patel, V., Kurioka, A., Jeffery, H.C., Wright, G., Tarff, S., Shawcross, D., Ryan, J.M., Evans, A., Azarian, S., Bajaj, J.S., Fagan, A., Patel, V., Mehta, K., Lopez, C., Simonova, M., Katzarov, K., Hadzhiolova, T., Pavlova, S., Wendon, J.A., Oo, Y.T., Klenerman, P., Williams, R. and Chokshi, S. 2018. Mucosa-associated invariant T cells link intestinal immunity with antibacterial immune defects in alcoholic liver disease. Gut. 67 (5), pp. 918-930. https://doi.org/10.1136/gutjnl-2017-314458

Iron enhances hepatic fibrogenesis and activates TGF-β signaling in murine hepatic stellate cells
Mehta, K.J., Coombes, J.D., Briones-Orta, M., Manka, P.P., Williams, R., Patel, V.B. and Sin, W.-K. 2018. Iron enhances hepatic fibrogenesis and activates TGF-β signaling in murine hepatic stellate cells. American Journal of the Medical Sciences. 355 (2), pp. 183-190. https://doi.org/10.1016/j.amjms.2017.08.012

A novel in vitro model of simulated twice a day iron supplementation for assessment of iron uptake and cellular damage
Apostolova, P., Blesia, C., Tossou, C., Renshaw, D., Farnaud, S., Evans, R. and Zariwala, M. 2017. A novel in vitro model of simulated twice a day iron supplementation for assessment of iron uptake and cellular damage. 7th Meeting of the International Bioiron Society. Los Angeles 07 - 11 May 2017 https://doi.org/10.1002/ajh.24812

Faecal Calprotectin and a Twenty-Four-Parameter Questionnaire in Autistic Children with Gastrointestinal Symptoms
Bramati-castellarin, I., Patel, V.B. and Drysdale, I.P. 2017. Faecal Calprotectin and a Twenty-Four-Parameter Questionnaire in Autistic Children with Gastrointestinal Symptoms. SM Journal of Psychiatry & Mental Health. 2 (1), p. 1009 1009.

Alcohol metabolism: implications for nutrution and health
Patel, V.B. and Preedy, V.R. 2017. Alcohol metabolism: implications for nutrution and health. in: Geissler, C. and Powers, H. (ed.) Human Nutrition, 13th Edition Oxford Oxford University Press. pp. 216-235

Comparative study of the bioavailability of different iron supplements to bacteria
Renshaw, D., Zariwala, M. and Farnaud, S. 2016. Comparative study of the bioavailability of different iron supplements to bacteria. European Iron Club. Innsbruck, Austria 07 - 10 Apr 2016

Fabrication and characterisation of novel protein-polysaccharide biopolymer based nanoparticles for iron delivery
Al-Obaidi, H., Patel, N., Ghafarzada, R., Malik, R., Musa, S., Chandramohan, S., Apostolova, P., Farnaud, S., Renshaw, D. and Zariwala, M. 2016. Fabrication and characterisation of novel protein-polysaccharide biopolymer based nanoparticles for iron delivery. European Iron Club. Innsbruck, Austria 07 - 10 Apr 2016

Beef protein isolate: a novel bio-matrix for formulating ferrous iron for nutritional applications
Zariwala, M., Farnaud, S., Renshaw, D. and Somavarapu, S. 2016. Beef protein isolate: a novel bio-matrix for formulating ferrous iron for nutritional applications. European Iron Club Meeting. Innsbruck, Austria 07 - 10 Apr 2016

Novel potato protein-polysaccharide nano-formulations for oral nutrient delivery
Zariwala, M., Somavarapu, S., Evans, R.W., Farnaud, S. and Renshaw, D. 2016. Novel potato protein-polysaccharide nano-formulations for oral nutrient delivery. Vitafoods. Geneva, Switzerland 30 - 30 May 2016

Iron enhances hepatic fibrogenesis through TGF-β activation
Mehta, K., Briones-Orta, M., Manka P., Coombes, J.D., Williams, R., Patel, V.B. and Syn, W-K. 2016. Iron enhances hepatic fibrogenesis through TGF-β activation. Hepatology. 64 (1 suppl), p. 360A. https://doi.org/10.1002/hep.28797

Characterization of hepcidin response to holotransferrin in novel recombinant TfR1 HepG2 cells
Mehta, K., Busbridge, Mark, Renshaw, D., Evans, R.W., Farnaud, S. and Patel, V. 2016. Characterization of hepcidin response to holotransferrin in novel recombinant TfR1 HepG2 cells. Blood Cells, Molecules, and Diseases. 61, pp. 37-45. https://doi.org/10.1016/j.bcmd.2016.06.008

Repeat-measures longitudinal study evaluating behavioural and gastrointestinal symptoms in children with autism before, during and after visceral osteopathic technique (VOT)
Bramati-Castellarin, I., Patel, V. and Drysdale, I.P. 2016. Repeat-measures longitudinal study evaluating behavioural and gastrointestinal symptoms in children with autism before, during and after visceral osteopathic technique (VOT). Journal of Bodywork and Movement Therapies. 20 (3), pp. 461-470. https://doi.org/10.1016/j.jbmt.2016.01.001

Betaine: Chemistry, Analysis, Function and Effects (Food and Nutritional Components in Focus)
Patel, V.B and Preedy, V.R. Patel, V.B. and Preedy, V.R. (ed.) 2015. Betaine: Chemistry, Analysis, Function and Effects (Food and Nutritional Components in Focus). Royal Society of Chemistry.

Molecular effects of alcohol on iron metabolism
Mehta, K., Farnaud, S. and Patel, V.B. 2015. Molecular effects of alcohol on iron metabolism . in: Patel, V.B. (ed.) Molecular Aspects of Alcohol and Nutrition Academic Press.

Alcohol Metabolism: General Aspects
Ghazali, R. and Patel, V.B. 2015. Alcohol Metabolism: General Aspects. in: Patel, V.B. (ed.) Molecular Aspects of Alcohol and Nutrition Academic Press.

Comparative study of bioavailability of different iron supplements to bacteria
Dagos, D., Selvam, P., Kelly, P., Evans, R., Zariwala, M., Renshaw, D. and Farnaud, S. 2015. Comparative study of bioavailability of different iron supplements to bacteria. 6th Meeting of the International Bioiron Society. Hangzhou, China 06 - 10 Sep 2015 Wiley. https://doi.org/10.1002/ajh.24277

A preliminary study of the link between iron increase in dopaminergic cells and Parkinson's disease
Mehta, K., Ahmed, B., Zariwala, M., Evans, R. and Farnaud, S. 2015. A preliminary study of the link between iron increase in dopaminergic cells and Parkinson's disease. 6th Meeting of the International Bioiron Society. Hangzhou, China 06 - 10 Sep 2015 Wiley. https://doi.org/10.1002/ajh.24277

What could insulin teach us about hepcidin? A comparative study between the iron hormone hepcidin and insulin
Mehta, K., Zariwala, M., Renshaw, D. and Farnaud, S. 2015. What could insulin teach us about hepcidin? A comparative study between the iron hormone hepcidin and insulin. 6th Meeting of the International Bioiron Society. Hangzhou, China 06 - 10 Sep 2015 Wiley. https://doi.org/10.1002/ajh.24277

Novel beta-casein nanocarriers for oral iron delivery
Zariwala, M., Somavarapu, S., Evans, R., Farnaud, S. and Renshaw, D. 2015. Novel beta-casein nanocarriers for oral iron delivery. 6th Meeting of the International Bioiron Society. Hangzhou, China 06 - 10 Sep 2015 Wiley. https://doi.org/10.1002/ajh.24277

Platform delivery technologies for nutraceutical applications
Zariwala, M., Somavarapu, S., Evans, R.W., Farnaud, S. and Renshaw, D. 2015. Platform delivery technologies for nutraceutical applications. Vitafoods . Geneva, Switzerland 05 - 07 May 2015

Novel whey protein isolate nanocarriers for oral micronutrient delivery
Farnaud, S., Renshaw, D., Somavarapu, S. and Zariwala, M. 2015. Novel whey protein isolate nanocarriers for oral micronutrient delivery. 9th NIZO Dairy Conference Milk Protein Functionality . Papendal, Netherlands 30 Sep - 02 Oct 2015

Biomarkers in Health and Disease: Further Knowledge
Rajendram, R., Rajendram, R., Patel, V.B. and Preedy, V.R. 2015. Biomarkers in Health and Disease: Further Knowledge. in: Preedy, V.R. and Patel, V.B. (ed.) General Methods in Biomarker Research and their Applications Netherlands Springer. pp. 1311-1316

Regional Increase in the Expression of the BCAT Proteins in Alzheimer's Disease Brain: Implications in Glutamate Toxicity
Hull, J., Patel, V.B., El Hindy, M., Hezwani, M., Love, S., Kehoe, P.G., Chalmers, C. and Conway, M.E. 2015. Regional Increase in the Expression of the BCAT Proteins in Alzheimer's Disease Brain: Implications in Glutamate Toxicity. Journal of Alzheimer's Disease. 45 (3), pp. 891-905. https://doi.org/10.3233/JAD-142970

New insights into the role of the branched-chain aminotransferase proteins in the human brain
Hull, J., Patel, V.B., Hutson, S.M. and Conway, M.E. 2015. New insights into the role of the branched-chain aminotransferase proteins in the human brain. Journal of Neuroscience Research. 93, pp. 987-998. https://doi.org/10.1002/jnr.23558

Characterisation of hepcidin response to holotransferrin treatment in CHO TRVb-1 cells
Mehta, K., Greenwell, P., Renshaw, D., Busbridge, Mark, Garcia, M, Farnaud, S. and Patel, V. B. 2015. Characterisation of hepcidin response to holotransferrin treatment in CHO TRVb-1 cells. Blood Cells, Molecules, and Diseases. 55 (2), pp. 110-118. https://doi.org/10.1016/j.bcmd.2015.05.002

Betaine, in context
Mehta, K. and Patel, V. 2015. Betaine, in context. in: Preedy, V.R. (ed.) Betaine: chemistry, analysis, function and effects Royal Society of Chemistry.

A human cell model of Parkinson’s disease confirms iron accumulation in dopaminergic neurons following 6-OHDOPA treatment
Zariwala, M. and Farnaud, S. 2014. A human cell model of Parkinson’s disease confirms iron accumulation in dopaminergic neurons following 6-OHDOPA treatment. European Iron Club Annual Meeting 2014. Verona, Italy 11 - 14 Sep 2014

Fabrication and characterization of novel hydrophobically modified chitosan nanoliposomes for oral iron delivery
Zariwala, M., Bendre, H., Markiv, A., Farnaud, S., Somavarapu, S. and Renshaw, D. 2014. Fabrication and characterization of novel hydrophobically modified chitosan nanoliposomes for oral iron delivery. European Iron Club Annual Meeting 2014. Verona, Italy 11 - 14 Sep 2014

Cardiovascular disease in aging and the role of oxidative stress
Alzaid, F., Patel, V. and Preedy, V.R. 2014. Cardiovascular disease in aging and the role of oxidative stress. in: Preedy, V.R. (ed.) Aging: oxidative stress and dietary antioxidants Academic Press. pp. 23-36

Ascorbyl palmitate/DSPE-PEG nanocarriers for oral iron delivery: Preparation, characterisation and in vitro evaluation
Zariwala, M.G., Farnaud, S., Merchant, Z., Somavarapu, S. and Renshaw, D. 2014. Ascorbyl palmitate/DSPE-PEG nanocarriers for oral iron delivery: Preparation, characterisation and in vitro evaluation. Colloids and Surfaces B: Biointerfaces. 115 (3), pp. 86-92. https://doi.org/10.1016/j.colsurfb.2013.11.028

The branched-chain aminotransferase proteins: novel redox chaperones for protein disulfide isomerase: implications in Alzheimer’s disease
Conway, M.E., El Hindy, M., Hezwani, M., Hull, J., Corry, D., Mansbridge, A., Hassler, M., Patel, V., Kehoe, P.G., Love, S., Harris, M., Forshaw, T., Lee, C.S., El Amraoui, F. and Wilson, A. 2014. The branched-chain aminotransferase proteins: novel redox chaperones for protein disulfide isomerase: implications in Alzheimer’s disease. Antioxidants and Redox Signaling. 20 (16), pp. 2497-2513. https://doi.org/10.1089/ars.2012.4869

A novel approach to oral iron delivery using ferrous sulphate loaded solid lipid nanoparticles
Gulrez Zariwala, M., Elsaid, N., Jackson, T.L., Corral López, F., Farnaud, S., Somavarapu, S. and Renshaw, D. 2013. A novel approach to oral iron delivery using ferrous sulphate loaded solid lipid nanoparticles. International Journal of Pharmaceutics. 456 (2), pp. 400-407. https://doi.org/10.1016/j.ijpharm.2013.08.070

Preparation and Characterisation of Solid Lipid Particles for Oral Iron Delivery
Zariwala, M., Farnaud, S., Somavarapu, S. and Renshaw, D. 2013. Preparation and Characterisation of Solid Lipid Particles for Oral Iron Delivery. Fifth Congress of the International BioIron Society (IBIS), Biennial World Meeting. University College London 14 - 18 Apr 2013 Wiley. https://doi.org/10.1002/ajh.23453

Hepcidin transcription and peptide secretion are governed by different regulatory mechanisms
Mehta, K., Patel, V., Busbridge, M., Renshaw, D., Zariwala, M., Evans, R. and Farnaud, S. 2013. Hepcidin transcription and peptide secretion are governed by different regulatory mechanisms. Fifth Congress of the International BioIron Society (IBIS), Biennial World Meeting. University College London 14 - 18 Apr 2013 Wiley. https://doi.org/10.1002/ajh.23453

Interlinking diet, nutrition, menopause and recommended resources
Rajendram, R., Rajendram, R., Patel, V. and Preedy, V.R. 2013. Interlinking diet, nutrition, menopause and recommended resources. in: Hollins Martin, C.J., Watson, R.R. and Preedy, V.R. (ed.) Nutrition and diet in menopause Springer. pp. 451-456

Effect of Salvia miltiorrhiza on antioxidant enzymes in diabetic patients
Quan, Q., Quan, S. and Patel, V. 2013. Effect of Salvia miltiorrhiza on antioxidant enzymes in diabetic patients. in: Preedy, V.R. (ed.) Diabetes: oxidative stress and dietary antioxidants Academic Press. pp. 79-87

Hepcidin transcription and peptide secretion are governed by different regulatory mechanisms
Mehta, K., Patel, V., Busbridge Mark, Renshaw, D., Zariwala, M.G., Evans, R. and Farnaud, S. 2013. Hepcidin transcription and peptide secretion are governed by different regulatory mechanisms. American Journal of Hematology. 88, p. E55.

The role of cancer stem cells in osteosarcoma
Jenks, A., Smith, C.L., Patel, V. and Clements, M.O. 2013. The role of cancer stem cells in osteosarcoma. International society for stem cell research conference. Boston (Massachusetts, USA) June 12 – 15 2013

Damaging effect of free fatty acids and alcohol on hepatic mitochondrial function
Gyamfi, D., Clemens, D.L. and Patel, V. 2013. Damaging effect of free fatty acids and alcohol on hepatic mitochondrial function. Alcohol & Alcoholism. 48, pp. i48-i50.

Evaluation of behavioural and gastrointestinal symptoms in autistic children after visceral osteopathic treatment
Castellarin, I.B., Drysdale, I. and Patel, V. 2013. Evaluation of behavioural and gastrointestinal symptoms in autistic children after visceral osteopathic treatment. International Journal of Osteopathy. 16, pp. e13-e14.

Hepatic mitochondrial dysfunction induced by fatty acids and ethanol
Gyamfi, D., Everitt, H.E., Tewfik, I., Clemens, D.L. and Patel, V. 2012. Hepatic mitochondrial dysfunction induced by fatty acids and ethanol. Free Radical Biology & Medicine. 53 (11), pp. 2131-2145. https://doi.org/10.1016/j.freeradbiomed.2012.09.024

The transfer of iron between ceruloplasmin and transferrins
White, K.N., Conesa, C., Sánchez, L., Amini, M., Farnaud, S., Lorvoralaka, C. and Evans, R.W. 2012. The transfer of iron between ceruloplasmin and transferrins. Biochimica et Biophysica Acta: general subjects. 1820 (3), pp. 411-416. https://doi.org/10.1016/j.bbagen.2011.10.006

Increased transferrin-bound iron uptake in HepG2 cells is followed by an increase in expression of the iron hormone hepcidin pre-and post-translationally
Mehta, K., Patel, V., Busbridge Mark, Renshaw, D., Zariwala, M., Evans, R. and Farnaud, S. 2012. Increased transferrin-bound iron uptake in HepG2 cells is followed by an increase in expression of the iron hormone hepcidin pre-and post-translationally. European Iron Club Annual Meeting 2012. Rennes, France 29 - 31 Aug 2012

Comparison of iron absorption from iron supplement preparations using an in vitro Caco-2 model
Zariwala, M., Farnaud, S. and Renshaw, D. 2012. Comparison of iron absorption from iron supplement preparations using an in vitro Caco-2 model. European Iron Club Annual Meeting 2012. Rennes, France 29 - 31 Aug 2012

Chinese herbal products in the prevention and treatment of liver disease
Gyamfi, D., Everitt, H.E. and Patel, V. 2012. Chinese herbal products in the prevention and treatment of liver disease. in: Watson, R.R. and Preedy, V.R. (ed.) Bioactive food as dietary interventions for liver and gastrointestinal disease Academic Press. pp. 537-550

Dietary sugars: TLC screening of sugars in urine and blood samples
Alonso-Fernandez, J.R. and Patel, V. 2012. Dietary sugars: TLC screening of sugars in urine and blood samples. in: Preedy, V.R. (ed.) Dietary sugars: chemistry, analysis, function and effects Royal Society of Chemistry. pp. 186-205

Alterations to liver energy metabolism and cell death following alcohol exposure
Gyamfi, D., Clemens, D.L. and Patel, V. 2011. Alterations to liver energy metabolism and cell death following alcohol exposure. Alcohol & Alcoholism. 46, pp. p47-48.

Transferrin receptor 2 is crucial for iron sensing in human hepatocytes
Rapisarda, C., Puppi, J., Hughes, R.D., Dhawan, A., Farnaud, S., Evans, R.W. and Sharp, P.A. 2010. Transferrin receptor 2 is crucial for iron sensing in human hepatocytes. American Journal of Physiology: Gastrointestinal and liver physiology. 299 (3), pp. G778-G783. https://doi.org/10.​1152/​ajpgi.​00157.​2010

Saliva: physiology and diagnostic potential in health and disease
Farnaud, S., Kosti, O., Getting, S.J. and Renshaw, D. 2010. Saliva: physiology and diagnostic potential in health and disease. ScientificWorldJournal. 10, pp. 434-456. https://doi.org/10.1100/tsw.2010.38

Opinion: Microdosing: safer clinical trials
Langley, G. and Farnaud, S. 2010. Opinion: Microdosing: safer clinical trials. Bioanalysis. 2 (3), pp. 393-395.

Apoptosis in alcoholic liver disease
Gyamfi, D., Everitt, H.E. and Patel, V. 2010. Apoptosis in alcoholic liver disease. in: Preedy, V.R. (ed.) Apoptosis: modern insights into disease from molecules to man Science Publishers. pp. 211-233

The effect of alcohol exposure on liver energy metabolism and cell death
Gyamfi, D., Clemens, D.L. and Patel, V. 2010. The effect of alcohol exposure on liver energy metabolism and cell death. Hepatology. 52, p. 455A.

The Dr Hadwen Trust for humane research: 39 years of replacement science
Farnaud, S. 2009. The Dr Hadwen Trust for humane research: 39 years of replacement science. Alternatives to Laboratory Animals. 37 (S2), pp. 39-43.

The evolution of the three Rs
Farnaud, S. 2009. The evolution of the three Rs. Alternatives to Laboratory Animals. 37 (3), pp. 249-254.

S-Nitrosoglutathione inactivation of the mitochondrial and cytosolic BCAT proteins: S-Nitrosation and S-Thiolation
Coles, S.J., Easton, P., Sharrod, H., Hutson, S.M., Hancock, J., Patel, V. and Conway, M.E. 2009. S-Nitrosoglutathione inactivation of the mitochondrial and cytosolic BCAT proteins: S-Nitrosation and S-Thiolation. Biochemistry. 48 (3), pp. 645-656. https://doi.org/10.1021/bi801805h

Liver metabolism: biochemical and molecular regulations
Gyamfi, D. and Patel, V. 2009. Liver metabolism: biochemical and molecular regulations. in: Preedy, V.R. (ed.) Nutrition, diet therapy, and the liver London CRC Press. pp. 3-15

Hepatic oxidative stress and apoptosis following acute alcohol
Everitt, H.E., Tewfik, I., Preedy, V.R. and Patel, V. 2009. Hepatic oxidative stress and apoptosis following acute alcohol. Alcohol & Alcoholism. 44, p. p85.

Identification of an iron-hepcidin complex
Farnaud, S., Rapisarda, C., Bui, T.T.T., Drake, A.F., Cammack, R. and Evans, R.W. 2008. Identification of an iron-hepcidin complex. Biochemical Journal. 413 (3), pp. 553-557. https://doi.org/10.1042/BJ20080406

Isolation of lactoferrin from milk of different species: calorimetric and antimicrobial studies
Conesa, C., Sánchez, L., Rota, C., Pérez, M.D., Calvo, M., Farnaud, S. and Evans, R.W. 2008. Isolation of lactoferrin from milk of different species: calorimetric and antimicrobial studies. Comparative Biochemistry and Physiology. Part B: Biochemistry & Molecular Biology. 150 (1), pp. 131-139. https://doi.org/10.1016/j.cbpb.2008.02.005

The interaction of arginine- and tryptophan-rich cyclic hexapeptides with Escherichia coli membranes
Junkes, C., Wessolowski, A., Farnaud, S., Evans, R.W., Good, L., Bienert, M. and Dathe, M. 2008. The interaction of arginine- and tryptophan-rich cyclic hexapeptides with Escherichia coli membranes. Journal of Peptide Science. 14 (4), pp. 535-543. https://doi.org/10.1002/psc.940

Tomatoes: origin, cultivation techniques, and germplasm resources
da Silva, D.J.H., Abreu, F.B., Caliman, F.R.B., Antonio, A.C. and Patel, V. 2008. Tomatoes: origin, cultivation techniques, and germplasm resources. in: Preedy, V.R. and Watson, R.R. (ed.) Tomatoes and tomato products: nutritional, medicinal and therapeutic properties CRC Press. pp. 3-26

Biochemical and spectroscopic studies of human melanotransferrin (MTf): electron-paramagnetic resonance evidence for a difference between the iron-binding site of MTf and other transferrins
Farnaud, S., Amini, M., Rapisarda, C., Cammack, R., Buic, T., Drake, A.F., Evans, R.W., Rahmanto, Y.S. and Richardson, D.R. 2008. Biochemical and spectroscopic studies of human melanotransferrin (MTf): electron-paramagnetic resonance evidence for a difference between the iron-binding site of MTf and other transferrins. International Journal of Biochemistry & Cell Biology. 40 (12), pp. 2739-2745. https://doi.org/10.1016/j.biocel.2008.07.003

Effects of 4-hydroxynonenal on mitochondrial 3-hydroxy-3methylglutaryl (HMG-CoA) synthase
Patel, V., Spencer, C.H., Young, T.A., Lively, M.O. and Cunningham, C.C. 2007. Effects of 4-hydroxynonenal on mitochondrial 3-hydroxy-3methylglutaryl (HMG-CoA) synthase. Free Radical Biology and Medicine. 43 (11), pp. 1499-1507. https://doi.org/10.1016/j.freeradbiomed.2007.08.004

Nutrition and alcoholic liver disease
Everitt, H.E., Patel, V. and Tewfik, I. 2007. Nutrition and alcoholic liver disease. Nutrition Bulletin. 32 (2), pp. 138-144. https://doi.org/10.1111/j.1467-3010.2007.00627.x

Nutrition and alcoholic liver disease
Everitt, H.E., Patel, V.B. and Tewfik, I. 2007. Nutrition and alcoholic liver disease. Nutrition Bulletin. 32 (2), pp. 138-144. https://doi.org/10.1111/j.1467-3010.2007.00627

Characterisation of recombinant unglycosylated human serum transferrin purified from Saccharomyces cerevisiae
Sargent, P.J., Farnaud, S., Cammack, R., Zoller, H.M.P. and Evans, R.W. 2006. Characterisation of recombinant unglycosylated human serum transferrin purified from Saccharomyces cerevisiae. BioMetals. 19 (5), pp. 513-519. https://doi.org/10.1007/s10534-005-5532-6

Modelling of a metal-containing hepcidin
Farnaud, S., Patel, A. and Evans, R.W. 2006. Modelling of a metal-containing hepcidin. BioMetals. 19 (5), pp. 527-533. https://doi.org/10.1007/s10534-005-5883-z

An overview of molecular aspects of iron metabolism
Syed, B.A., Sargent, P.J., Farnaud, S. and Evans, R.W. 2006. An overview of molecular aspects of iron metabolism. Hemoglobin. 30 (1), pp. 69-80. https://doi.org/10.1080/03630260500455318

Towards a tree-induction approach to antimicrobial activity analysis of cationic peptides
Farnaud, S., Wang, Z., Dybowski, R., Odell, E.W. and Evans, R.W. 2006. Towards a tree-induction approach to antimicrobial activity analysis of cationic peptides. Biochemistry and Cell Biology. 84 (3), p. 394. https://doi.org/10.1139/O06-900

Structure/function overview of proteins involved in iron storage and transport
Sargent, P.J., Farnaud, S. and Evans, R.W. 2005. Structure/function overview of proteins involved in iron storage and transport. Current Medicinal Chemistry. 12 (23), pp. 2683-2693. https://doi.org/10.2174/092986705774462969

Protein adduct species in muscle and liver of rats following acute ethanol administration
Patel, V., Worrall, S., Emery, P.W. and Preedy, V.R. 2005. Protein adduct species in muscle and liver of rats following acute ethanol administration. Alcohol & Alcoholism. 40 (6), pp. 485-493. https://doi.org/10.1093/alcalc/agh196

Lactoferrin: the conductor of the immunological system?
Farnaud, S. and Evans, R.W. 2005. Lactoferrin: the conductor of the immunological system? in: Veskler, B.A. (ed.) New research on immunology New York Nova Science Publishers.

Variation in antimicrobial activity of lactoferricin-derived peptides explained by structure modelling
Farnaud, S., Patel, A., Odell, E.W. and Evans, R.W. 2004. Variation in antimicrobial activity of lactoferricin-derived peptides explained by structure modelling. FEMS Microbiology Letters. 238 (1), pp. 221-226. https://doi.org/10.1111/j.1574-6968.2004.tb09759.x

Liver dysfunction induced by bile duct ligation and galactosamine injection alters cardiac protein synthesis
Hunter, R.V., Patel, V., Baker, A.J. and Preedy, V.R. 2004. Liver dysfunction induced by bile duct ligation and galactosamine injection alters cardiac protein synthesis. Metabolism: Clinical and Experimental. 53 (8), pp. 964-968. https://doi.org/10.1016/j.metabol.2003.11.015

The plug domain of a neisserial TonB-dependent transporter retains structural integrity in the absence of its transmembrane β-barrel
Oke, M., Sarra, R., Ghirlando, R., Farnaud, S., Gorringe, A.R., Evans, R.W. and Buchanan, S.K. 2004. The plug domain of a neisserial TonB-dependent transporter retains structural integrity in the absence of its transmembrane β-barrel. FEBS Letters. 564 (3), pp. 294-300. https://doi.org/10.1016/S0014-5793(04)00196-6

Interactions of lactoferricin-derived peptides with LPS and antimicrobial activity
Farnaud, S., Spiller, C., Moriarty, L.C., Patel, A., Gant, V., Odell, E.W. and Evans, R.W. 2004. Interactions of lactoferricin-derived peptides with LPS and antimicrobial activity. FEMS Microbiology Letters. 233 (2/29), pp. 193-199. https://doi.org/10.1111/j.1574-6968.2004.tb09482.x

Lactoferrin: a multifunctional protein with antimicrobial properties
Farnaud, S. and Evans, R.W. 2003. Lactoferrin: a multifunctional protein with antimicrobial properties. Molecular Immunology. 40 (7), pp. 395-405. https://doi.org/10.1016/S0161-5890(03)00152-4

Protein metabolism in alcohol misuse and toxicity
Preedy, V.R., Koll, M., Adachi, J., Mantle, D., Patel, V. and Peters, T. 2003. Protein metabolism in alcohol misuse and toxicity. in: Watson, R.R. and Preedy, V.R. (ed.) Nutrition and alcohol: linking nutrient interactions and dietary intake London CRC Press. pp. 261-300

Chronic ethanol consumption increases the concentration of a 4-hydroxynonenal adduct with the mitochondrial hydroxy methyl glutaryl CoA synthase in liver
Patel, V., Spencer, C. and Cunningham, C.C. 2003. Chronic ethanol consumption increases the concentration of a 4-hydroxynonenal adduct with the mitochondrial hydroxy methyl glutaryl CoA synthase in liver. Hepatology. 38, p. p393.

Emerging techniques in biomedical research and their application to alcohol toxicity
Patel, V., Chaurand, P., Caprioli, R., Austen, B., Frears, E., Manca, F., Davies, H., Vrana, K., Wheeler, M. and Preedy, V.R. 2003. Emerging techniques in biomedical research and their application to alcohol toxicity. Alcoholism: Clinical and Experimental Research. 27 (2), pp. 348-353.

Support for a three-dimensional structure predicting a Cys-Glu-Lys catalytic triad for Pseudomonas aeruginosa amidase comes from site-directed mutagenesis and mutations altering substrate specificity
Novo, C., Farnaud, S., Tata, R., Clemente, A. and Brown, P.R. 2002. Support for a three-dimensional structure predicting a Cys-Glu-Lys catalytic triad for Pseudomonas aeruginosa amidase comes from site-directed mutagenesis and mutations altering substrate specificity. Biochemical Journal. 365 (3), pp. 731-738. https://doi.org/10.1042/BJ20011714

Altered hepatic mitochondrial ribosome structure following chronic ethanol consumption
Patel, V. and Cunningham, C.C. 2002. Altered hepatic mitochondrial ribosome structure following chronic ethanol consumption. Archives of Biochemistry and Biophysics. 398 (1), pp. 41-50. https://doi.org/10.1006/abbi.2001.2701

Chronic ethanol consumption increases the formation of an aldehyde-protein adduct in hepatic mitochondria
Patel, V., Young, T.A. and Cunningham, C.C. 2002. Chronic ethanol consumption increases the formation of an aldehyde-protein adduct in hepatic mitochondria. Alcoholism: Clinical and Experimental Research.

Cardioprotective effect of propranolol from alcohol-induced heart muscle damage as assessed by plasma cardiac troponin-T.
Patel, V., Ajmal, R., Sherwood, R., Sullivan, A., Richardson, P. and Preedy, V.R. 2001. Cardioprotective effect of propranolol from alcohol-induced heart muscle damage as assessed by plasma cardiac troponin-T. Alcoholism: Clinical and Experimental Research. 25 (6), pp. 882-889. https://doi.org/10.1111/j.1530-0277.2001.tb02294.x

Diarrhea reduces the rates of cardiac protein synthesis in myofibrillar protein fractions in rats in vivo
Hunter, R.V., Patel, V., Miell, J., Wong, H.J., Marway, J., Richardson, P. and Preedy, V.R. 2001. Diarrhea reduces the rates of cardiac protein synthesis in myofibrillar protein fractions in rats in vivo. Journal of Nutrition. 131 (5), pp. 1513-1519.

Acute doxorubicin (adriamycin) dosage does not reduce cardiac protein synthesis in vivo, but decreases diaminopeptidase I and proline endopeptidase activities
Zima, T., Tesar, V., Mantle, D., Koll, M., Patel, V., Richardson, P. and Preedy, V.R. 2001. Acute doxorubicin (adriamycin) dosage does not reduce cardiac protein synthesis in vivo, but decreases diaminopeptidase I and proline endopeptidase activities. Experimental and Molecular Pathology. 70 (2), pp. 154-161. https://doi.org/10.1006/exmp.2000.2353

Physiochemical properties of rat liver mitochondrial ribosomes
Patel, V., Cunningham, C.C. and Hantgan, R. 2001. Physiochemical properties of rat liver mitochondrial ribosomes. Journal of Biological Chemistry. 276 (9), pp. 6739-6746. https://doi.org/10.1074/jbc.M005781200

In vivo protein synthetic rates of atrial, ventricular, and pulmonary tissue proteins in aortic constriction, goldblatt, and bromoethylamine models of hypertension
Siddiq, T., Patel, V., Sherwood, R., Richardson, P. and Preedy, V.R. 2001. In vivo protein synthetic rates of atrial, ventricular, and pulmonary tissue proteins in aortic constriction, goldblatt, and bromoethylamine models of hypertension. Experimental and Molecular Pathology. 70 (1), pp. 19-30. https://doi.org/10.1006/exmp.2000.2333

Ethanol and oxidative stress
Sun, A., Ingelman-Sundberg, M., Neve, E., Matsumoto, H., Nishitani, Y., Minowa, Y., Fukui, Y., Bailey, S., Patel, V., Cunningham, C.C., Zima, T., Fialova, L., Mikulikova, L., Popov, P., Malbohan, I., Janebova, M., Nespor, K. and Sun, G. 2001. Ethanol and oxidative stress. Alcoholism: Clinical and Experimental Research. 25 (5 Suppl.), pp. 237S-243S.

Alpha-Tocopherol supplementation does not prevent acute alcohol-induced heart muscle damage
Koll, M., Patel, V., Sherwood, R.A., Seitz, H.K., Simanowski, U.A., Richardson, P.J., Peters, T.J. and Preedy, V.R. 2001. Alpha-Tocopherol supplementation does not prevent acute alcohol-induced heart muscle damage. Proceedings of the Nutrition Society. 60, p. P125A.

Ethanol and protein metabolism
Cunningham, C.C., Preedy, V.R., Paice, A., Hesketh, J., Peters, T., Patel, V., Volpi, E., Mawatari, K., Masaki, H., Mori, H. and Torii, K. 2001. Ethanol and protein metabolism. Alcoholism: Clinical and Experimental Research. 25 (5 Suppl.), pp. 262S-268S.

Chronic ethanol consumption alters the glutathione/glutathione peroxidase-1 system and protein oxidation status in rat liver
Bailey, S., Patel, V., Young, T.A., Asayama, K. and Cunningham, C.C. 2001. Chronic ethanol consumption alters the glutathione/glutathione peroxidase-1 system and protein oxidation status in rat liver. Alcoholism: Clinical and Experimental Research. 25 (5), pp. 726-733.

Evidence that cysteine-166 is the active-site nucleophile of Pseudomonas aeruginosa amidase: crystallization and preliminary X-ray diffraction analysis of the enzyme
Farnaud, S., Tata, R., Sohi, M.K., Wan, T., Brown, P.R. and Sutton, B.J. 1999. Evidence that cysteine-166 is the active-site nucleophile of Pseudomonas aeruginosa amidase: crystallization and preliminary X-ray diffraction analysis of the enzyme. Biochemical Journal. 340 (3), pp. 711-714.