A Prospective Randomized Controlled Trial to Study the Impact of a Nutrition-Sensitive Intervention on Adult Women With Cancer Cachexia Undergoing Palliative Care in India

Kapoor, N., Naufahu, J., Tewfik, S., Bhatnagar, S., Garg, R. and Tewfik, I. 2017. A Prospective Randomized Controlled Trial to Study the Impact of a Nutrition-Sensitive Intervention on Adult Women With Cancer Cachexia Undergoing Palliative Care in India. Integrative Cancer Therapies. 6 (1), pp. 74-84.

TitleA Prospective Randomized Controlled Trial to Study the Impact of a Nutrition-Sensitive Intervention on Adult Women With Cancer Cachexia Undergoing Palliative Care in India
AuthorsKapoor, N., Naufahu, J., Tewfik, S., Bhatnagar, S., Garg, R. and Tewfik, I.
Abstract

Purpose. Advanced cancer patients with disease progression develop cachexia. Nevertheless, cancer patients at nutritional risk have shown improved body weight and quality of life with oral nutritional supplements. Method. This was a randomized controlled trial in adult female cancer patients (n = 63) attending palliative clinics, with symptoms of cachexia. Eligible patients were randomly distributed into control (n = 33) and intervention (n = 30) groups. Both groups were provided with nutritional and physical activity counseling, but the intervention group received an additional 100 g of Improved Atta (IAtta) for 6 months daily consumption. This study was designed to assess the efficacy of IAtta (with counseling) in enhancing the health status of cachexic patients. Anthropometric measurements, dietary intake, physical activity level and quality of life parameters were assessed at baseline, after 3 months, and at the end of 6 months. Results. Patients in the control group (n = 15) had significantly decreased body weight (P = .003), mid–upper-arm circumference (P = .002), and body fat (P = .002) by the end of intervention. A trend of body weight gain in the intervention group (n = 17; P = .08) and significant increase of body fat (P = .002) was observed; moreover, patients reported a significant improvement in fatigue (P = .002) and appetite scores (P = .006) under quality-of-life domains at the end of intervention. Conclusions. Embedding a nutrition-sensitive intervention ( IAtta ) within Indian palliative care therapy may improve quality of life and stabilize body weight in cancer cachexia patients.

JournalIntegrative Cancer Therapies
Journal citation6 (1), pp. 74-84
ISSN1534-7354
Year2017
PublisherSage
Publisher's versionIntegr Cancer Ther-2016-Kapoor-1534735416651968.pdf
Digital Object Identifier (DOI)doi:10.1177/1534735416651968
Publication dates
Published online01 Jun 2016
Published01 Jun 2016
Published in printMar 2017
LicenseCC BY-NC 3.0

Related outputs

Nutritional Management in Polycystic Ovary Syndrome: Challenges and opportunities
Hmedeh, C., Ghazeeri, G. and Tewfik, I. 2018. Nutritional Management in Polycystic Ovary Syndrome: Challenges and opportunities. International Journal of Food Safety, Nutrition and Public Health.

Evaluation of a photographic food atlas as a tool for quantifying food portion size in the United Arab Emirates
Ali, H., Platat, C., El Mesmoudi, N., El Sadig, M. and Tewfik, I. 2018. Evaluation of a photographic food atlas as a tool for quantifying food portion size in the United Arab Emirates. PLoS ONE. 13 (4), p. 0196389.

Evaluation of plasma neurotransmitters in children living with Attention-Deficit Hyperactivity Disorder (ADHD)
Meguid, N., Anwar, M., Hussein, J., Hasan, H., Hashish, A., Seleet, F., Foda, M. and Tewfik, I. 2018. Evaluation of plasma neurotransmitters in children living with Attention-Deficit Hyperactivity Disorder (ADHD). Bioscience Research. 15 (1), pp. 152-159.

High intensity exercise decreases IP6K1 muscle content & improves insulin sensitivity in glucose intolerant individuals
Naufahu, J., Elliott, B., Markiv, A., Dunning-Foreman, P., McGrady, M., Howard, D., Watt, P.W. and Mackenzie, R.W.A. 2018. High intensity exercise decreases IP6K1 muscle content & improves insulin sensitivity in glucose intolerant individuals. Journal of Clinical Endocrinology and Metabolism. 103 (4), pp. 1479-1490.

Melanin-concentrating hormone in peripheral circulation in the human
Naufahu, J., Alzaid, F., Fiuza Brito, M., Doslikova, B., Valencia, T. and Murray, J.F. 2017. Melanin-concentrating hormone in peripheral circulation in the human. Journal of Endocrinology. 232, pp. 513-523.

Genome instability in childhood obesity: A conceptual framework for an assessment, intervention and monitoring programme of inflammation and DNA damage in paediatric obesity
Usman, M., Tewfik, I. and Volpi, E. 2017. Genome instability in childhood obesity: A conceptual framework for an assessment, intervention and monitoring programme of inflammation and DNA damage in paediatric obesity. International Journal of Food, Nutrition and Public Health. 9 (1), pp. 1-12.

Risk Factors for Maternal Vitamin D Deficiency within the United Arab Emirates
Hussein, I., Taha, Z., Tewfik, I., Badawi, S., Siddieg, H., Adegboye, A.R. and McGrady, K. 2016. Risk Factors for Maternal Vitamin D Deficiency within the United Arab Emirates. Journal of Pregnancy and Child Health. 3 (5), p. 1000276.

To assess the effectiveness of tailored food recipe in attenuating the progression of cancer cachexia to refractory cachexia in adult female patients undergoing palliative care in India
Kapoor, N. 2016. To assess the effectiveness of tailored food recipe in attenuating the progression of cancer cachexia to refractory cachexia in adult female patients undergoing palliative care in India. PhD thesis University of Westminster Life Sciences

A comparative study: long and short term effect of a nutrition sensitive approach to delay the progression of HIV to AIDS among people living with HIV (PLWH) in Nigeria
Amlogu, A., Tewfik, S., Wambebe, C. and Tewfik, I. 2016. A comparative study: long and short term effect of a nutrition sensitive approach to delay the progression of HIV to AIDS among people living with HIV (PLWH) in Nigeria. Functional Foods in Health and Disease. 6 (2), pp. 79-90.

American skullcap (Scutellaria lateriflora): a randomised, double-blind placebo-controlled crossover study of its effects on mood in healthy volunteers
Brock, C., Whitehouse, J., Tewfik, I. and Towell, A. 2014. American skullcap (Scutellaria lateriflora): a randomised, double-blind placebo-controlled crossover study of its effects on mood in healthy volunteers. Phytotherapy Research. 28 (5), pp. 692-698.

The roles of melanin-concentrating hormone in energy balance and reproductive function: are they connected?
Naufahu, J., Cunliffe, A. and Murray, J.F. 2013. The roles of melanin-concentrating hormone in energy balance and reproductive function: are they connected? Reproduction. 146, pp. R141-R150.

Identity issues surrounding American skullcap (Scutellaria lateriflora) and an optimised high performance liquid chromatography method to authenticate commercially available products
Brock, C., Whitehouse, J., Tewfik, I. and Towell, A. 2013. Identity issues surrounding American skullcap (Scutellaria lateriflora) and an optimised high performance liquid chromatography method to authenticate commercially available products. Journal of Herbal Medicine. 3 (2), pp. 57-64.

The effects of consuming a medium-high protein diet on weight loss, body composition and satiety
Hutson, R. and Naufahu, J. 2013. The effects of consuming a medium-high protein diet on weight loss, body composition and satiety. International Journal of Food, Nutrition and Public Health. 6 (2), pp. 105-121.

Hepatic mitochondrial dysfunction induced by fatty acids and ethanol
Gyamfi, D., Everitt, H.E., Tewfik, I., Clemens, D.L. and Patel, V. 2012. Hepatic mitochondrial dysfunction induced by fatty acids and ethanol. Free Radical Biology & Medicine. 53 (11), pp. 2131-2145.

The use of Scutellaria lateriflora: a pilot survey amongst herbal medicine practitioners
Brock, C., Whitehouse, J., Tewfik, I. and Towell, A. 2012. The use of Scutellaria lateriflora: a pilot survey amongst herbal medicine practitioners. Journal of Herbal Medicine. 2 (2), pp. 34-41.

Obesity and low vision as a result of excessive internet use, and television viewing
Bener, A., Al-Mahdi, H.S., Ali, A.I., Al-Nufal, M., Vachhani, P.J. and Tewfik, I. 2011. Obesity and low vision as a result of excessive internet use, and television viewing. International Journal of Food Sciences and Nutrition. 62 (1), pp. 60-62.

Globesity in action: systematic review and pilot intervention to assess the potential health benefit of moderate physical activity
Salah, M. and Tewfik, I. 2011. Globesity in action: systematic review and pilot intervention to assess the potential health benefit of moderate physical activity. in: Ahmed, A. and Busler, M. (ed.) World sustainable development outlook 2011. Sharing knowledge, making a difference: the role of international scientific cooperation World Association for Sustainable Development (WASD).

Conceptual framework of public health-nutrition intervention programme to attenuate the progression of HIV to AIDS among people living with HIV (PLWH) in Abuja, Nigeria
Amlogu, M.A., Tewfik, S., Wambebe, C., Godden, K. and Tewfik, I. 2011. Conceptual framework of public health-nutrition intervention programme to attenuate the progression of HIV to AIDS among people living with HIV (PLWH) in Abuja, Nigeria. in: Ahmed, A. and Busler, M. (ed.) World sustainable development outlook 2011. Sharing knowledge, making a difference: the role of international scientific cooperation World Association for Sustainable Development (WASD). pp. 11-20

American skullcap (Scutellaria lateriflora): an ancient remedy for today’s anxiety?
Brock, C., Whitehouse, J., Tewfik, I. and Towell, A. 2010. American skullcap (Scutellaria lateriflora): an ancient remedy for today’s anxiety? British Journal of Wellbeing. 1 (4), pp. 25-30.

Is Africa facing a nutrition transition under the double burden of disease?
Tewfik, I., Bener, A. and Tewfik, S. 2010. Is Africa facing a nutrition transition under the double burden of disease? in: Ahmed, A. and Nwankwo, S. (ed.) Achieving sustainable development in Africa: science, technology & innovation trajectory London World Association for Sustainable Development (WASD).

Circulating melanin concentrating hormone (MCH) concentrations in the menstrual cycle
Naufahu, J., Cunliffe, A. and Murray, J.F. 2010. Circulating melanin concentrating hormone (MCH) concentrations in the menstrual cycle. Society for Reproduction and Fertility. Sutton Bonnington 11th - 13th July 2010

Preliminary characterisation of the neuropeptide melanin concentrating hormone in humans
Naufahu, J. 2010. Preliminary characterisation of the neuropeptide melanin concentrating hormone in humans. PhD thesis University of Westminster School of Life Sciences

Childhood obesity prevention in Emirates (COPE): a conceptual framework for pilot intervention
Tewfik, I., Mackenzie, J., Cunliffe, A., Al-Dhaheri, A., Ali, H., Washi, S. and Platat, C. 2009. Childhood obesity prevention in Emirates (COPE): a conceptual framework for pilot intervention. in: Ahmed, A. (ed.) World sustainable development outlook: the impact of the global financial crisis on the environment, energy and sustainable development 2009 London World Association for Sustainable Development (WASD).

Nutritional quality of deep fried street-vended foods: a public health concern
Tewfik, I., Ismail, H. and Tewfik, S. 2009. Nutritional quality of deep fried street-vended foods: a public health concern. in: Ahmed, A. (ed.) World sustainable development outlook: the impact of the global financial crisis on the environment, energy and sustainable development 2009 London World Association for Sustainable Development (WASD).

Hepatic oxidative stress and apoptosis following acute alcohol
Everitt, H.E., Tewfik, I., Preedy, V.R. and Patel, V. 2009. Hepatic oxidative stress and apoptosis following acute alcohol. Alcohol & Alcoholism. 44, p. p85.

Assessment of shelf-life of irradiated frozen chicken
Alnasser, M.A., Park, S.F., Jenesson, P. and Tewfik, I. 2009. Assessment of shelf-life of irradiated frozen chicken. International Journal of Food Safety, Nutrition and Public Health. 2 (1), pp. 48-58.

Would it still be possible to identify irradiated lipid-containing foods towards the end of their shelf-life?
Tewfik, I. and Tewfik, S. 2008. Would it still be possible to identify irradiated lipid-containing foods towards the end of their shelf-life? Food Science and Technology International. 14 (6), pp. 519-524.

Extraction and identification of cyclobutanones from irradiated cheese employing a rapid direct solvent extraction method
Tewfik, I. 2008. Extraction and identification of cyclobutanones from irradiated cheese employing a rapid direct solvent extraction method. International Journal of Food Sciences and Nutrition. 59 (7 & 8), pp. 590-598.

Inter-laboratory trial to validate the direct solvent extraction method for the identification of 2-dodecylcyclobutanone in irradiated chicken and whole liquid egg
Tewfik, I. 2008. Inter-laboratory trial to validate the direct solvent extraction method for the identification of 2-dodecylcyclobutanone in irradiated chicken and whole liquid egg. Food Science and Technology International. 14 (3), pp. 277-283.

Does prolonged breastfeeding reduce the risk for childhood leukemia and lymphomas?
Bener, A., Hoffmann, G.F., Afify, Z., Rasul, K., Mian, M., Guiter, G. and Tewfik, I. 2008. Does prolonged breastfeeding reduce the risk for childhood leukemia and lymphomas? Minerva Pediatrica. 60 (2), pp. 155-161.

Nutraceuticals, functional foods and botanical dietary supplements; promote wellbeing and underpin public health
Tewfik, S. and Tewfik, I. 2008. Nutraceuticals, functional foods and botanical dietary supplements; promote wellbeing and underpin public health. World Review of Science, Technology and Sustainable Development. 5 (2), pp. 104-123.

Childhood obesity prevention (CHOP) programme: a conceptual framework for nutrition intervention
Tewfik, I. 2008. Childhood obesity prevention (CHOP) programme: a conceptual framework for nutrition intervention. International Journal of Food Safety, Nutrition and Public Health. 1 (1), pp. 16-32.

Metabolic Syndrome and its components among Qatari population
Musallam, M., Bener, A., Zirie, M., Al-Gaud, Y.K., Al-Hamaq, A.A., Othman, M.A. and Tewfik, I. 2008. Metabolic Syndrome and its components among Qatari population. International Journal of Food Safety, Nutrition and Public Health. 1 (1), pp. 88-102.

Impact of lifestyle and dietary habits on hypovitaminosis D in type 1 diabetes mellitus and healthy children from Qatar, a sun-rich country
Bener, A., Alsaied, A., Al-Ali, M., Hassan, A.S., Basha, B., Al-Kubaisi, A., Abraham, A., Mian, M., Guiter, G., Tewfik, I. and Agha, M. 2008. Impact of lifestyle and dietary habits on hypovitaminosis D in type 1 diabetes mellitus and healthy children from Qatar, a sun-rich country. Annals of Nutrition and Metabolism. 53 (3-4), pp. 215-222.

A rapid direct solvent extraction (DSE) method for the extraction of cyclobutanones from irradiated chicken and liquid whole egg
Tewfik, I. 2008. A rapid direct solvent extraction (DSE) method for the extraction of cyclobutanones from irradiated chicken and liquid whole egg. International Journal of Food Science and Technology. 43 (1), pp. 108-113.

Nutrition and alcoholic liver disease
Everitt, H.E., Patel, V. and Tewfik, I. 2007. Nutrition and alcoholic liver disease. Nutrition Bulletin. 32 (2), pp. 138-144.

The public health advocate: food irradiation's offer to food security
Tewfik, I. and Tewfik, S. 2007. The public health advocate: food irradiation's offer to food security. in: Ahmed, A. (ed.) Science, technology and sustainability in the Middle East and North Africa Genève InderScience. pp. 197-209

Competitive food safety program: the case of Qatar
Al-Hamaq, A.A., Zeyadah, S.S., Ahmed, A., Amuna, P. and Tewfik, I. 2007. Competitive food safety program: the case of Qatar. in: Ahmed, A. (ed.) Science, technology and sustainability in the Middle East and North Africa Genève InderScience. pp. 210-228

Book review: B. Freire Wilma (editor). Nutrition and an Active Life: From Knowledge to Action. Scientific and Technical Publication No. 612. Washington DC: Pan American Health Organization 2005. US$ 36·00 (paperback) pp. 260. ISBN: 92 75 11612 1
Tewfik, I. 2006. Book review: B. Freire Wilma (editor). Nutrition and an Active Life: From Knowledge to Action. Scientific and Technical Publication No. 612. Washington DC: Pan American Health Organization 2005. US$ 36·00 (paperback) pp. 260. ISBN: 92 75 11612 1. British Journal of Nutrition. 96 (4), p. 793.

Prevalence of overweight, obesity, and associated psychological problems in Qatari's female population
Bener, A. and Tewfik, I. 2006. Prevalence of overweight, obesity, and associated psychological problems in Qatari's female population. Obesity Reviews. 7 (2), pp. 139-145.

Industrial and dietetic applications of the food multimix (FMM) concept in meeting the nutritional needs of vulnerable groups in South Africa
Zotor, F., Amuna, P., Oldewage-Theron, W.H., Adewuya, T., Prinsloo, G., Chinyanga, Y., Tewfik, I. and Amuna, N. 2006. Industrial and dietetic applications of the food multimix (FMM) concept in meeting the nutritional needs of vulnerable groups in South Africa. Academic Journal of Vaal University of Technology. 3, pp. 54-67.

CO2 photoassimilation, chlorophyll fluorescence, lipid peroxidation and yield in cotton (Gossypium hirsutum L. cv Giza 65) in response to O3
Hassan, I.A. and Tewfik, I. 2006. CO2 photoassimilation, chlorophyll fluorescence, lipid peroxidation and yield in cotton (Gossypium hirsutum L. cv Giza 65) in response to O3. World Review of Science, Technology and Sustainable Development. 3 (1), pp. 70-79.

Prevalence of dieting, overweight, body image satisfaction and associated psychological problems in adolescent boys
Bener, A., Kamal, A., Tewfik, I. and Sabuncuoglu, O. 2006. Prevalence of dieting, overweight, body image satisfaction and associated psychological problems in adolescent boys. Nutrition & Food Science. 36 (5), pp. 295-304.

Would food irradiation as a means of technology transfer assist food productivity and security in Africa and sustain its development?
Tewfik, I., Amuna, P. and Zotor, F. 2004. Would food irradiation as a means of technology transfer assist food productivity and security in Africa and sustain its development? International Journal of Technology Policy and Management. 4 (1), pp. 44-52.

Human and economic development in developing countries: a public health dimension employing the food multimix concept
Amuna, P., Zotor, F. and Tewfik, I. 2004. Human and economic development in developing countries: a public health dimension employing the food multimix concept. World Review of Science, Technology and Sustainable Development. 1 (2), pp. 129-137.

The effect of intermittent heating on some chemical parameters of refined oils used in Egypt. A public health nutrition concern
Tewfik, I., Ismail, H. and Sumar, S. 1998. The effect of intermittent heating on some chemical parameters of refined oils used in Egypt. A public health nutrition concern. International Journal of Food Sciences and Nutrition. 49 (5), pp. 339-342.

A rapid supercritical fluid extraction method for the detection of 2-alkylcyclobutanones in gamma irradiated beef and chicken
Tewfik, I., Ismail, H. and Sumar, S. 1998. A rapid supercritical fluid extraction method for the detection of 2-alkylcyclobutanones in gamma irradiated beef and chicken. Lebensmittel-Wissenschaft und-Technologie = Journal of Food Sciences and Technology. 31 (4), pp. 366-370.

A rapid direct solvent extraction method (DSE-GC-MS) used to detect irradiated minced beef
Tewfik, I., Ismail, H. and Sumar, S. 1998. A rapid direct solvent extraction method (DSE-GC-MS) used to detect irradiated minced beef. Bulletin of High Institute of Public Health. 28 (3), pp. 85-92.

A rapid supercritical fluid extraction method for the qualitative detection of 2-alkylcyclobutanones in gamma-irradiated fresh and sea water fish
Tewfik, I. 1998. A rapid supercritical fluid extraction method for the qualitative detection of 2-alkylcyclobutanones in gamma-irradiated fresh and sea water fish. International Journal of Food Sciences and Nutrition. 50 (1), pp. 51-56.

A rapid method (SFE-GC-MS) used to detect irradiated minced beef
Tewfik, I., Ismail, H., Amine, E. and Rady, A. 1996. A rapid method (SFE-GC-MS) used to detect irradiated minced beef. Arab Journal of Nuclear Sciences and Applications. 29 (4), pp. 345-353.

Permalink - https://westminsterresearch.westminster.ac.uk/item/9wx85/a-prospective-randomized-controlled-trial-to-study-the-impact-of-a-nutrition-sensitive-intervention-on-adult-women-with-cancer-cachexia-undergoing-palliative-care-in-india


Share this
Tweet
Email