Dual production of polyhydroxyalkanoates and antibacterial/antiviral gold nanoparticles

Development of a highly degenerate primer-based molecular tool for detecting and classifying the four major classes of polyhydroxyalkanoate synthase (phaC) genes in bacteria
Ibrahim Osman, A., Noble, B., Percy, L. and Basnett, P. 2025. Development of a highly degenerate primer-based molecular tool for detecting and classifying the four major classes of polyhydroxyalkanoate synthase (phaC) genes in bacteria. Microbial Cell Factories. 24 24. https://doi.org/10.1186/s12934-025-02831-9

Curcumin and N-Acetylcysteine Nanocarriers Alone or Combined with Deferoxamine Target the Mitochondria and Protect against Neurotoxicity and Oxidative Stress in a Co-Culture Model of Parkinson’s Disease
Mursaleen, L., Chan, S.H.Y., Noble, B., Somavarapu, S. and Zariwala, M. 2023. Curcumin and N-Acetylcysteine Nanocarriers Alone or Combined with Deferoxamine Target the Mitochondria and Protect against Neurotoxicity and Oxidative Stress in a Co-Culture Model of Parkinson’s Disease. Antioxidants. 12 (1) 130. https://doi.org/10.3390/antiox12010130

Curcumin and N-Acetylcysteine Nanocarriers Alone or Combined with Deferoxamine Target the Mitochondria and Protect against Neurotoxicity and Oxidative Stress in a Co-Culture Model of Parkinson’s Disease
Mursaleen, L., Chan, S., Noble, B., Somavarapu, S. and Zariwala, M. 2023. Curcumin and N-Acetylcysteine Nanocarriers Alone or Combined with Deferoxamine Target the Mitochondria and Protect against Neurotoxicity and Oxidative Stress in a Co-Culture Model of Parkinson’s Disease. Antioxidants. 12 (1) 130. https://doi.org/10.3390/antiox12010130

Enhanced production of biobased, biodegradable, Poly(3-hydroxybutyrate) using an unexplored marine bacterium Pseudohalocynthiibacter aestuariivivens, isolated from highly polluted coastal environment.
Esposito, Fortunato Palma, Vecchiato, Vittoria, Buonocore, Carmine, Tedesco, Pietro, Noble, Brendon, Basnett, Pooja and de Pascale, Donatella 2023. Enhanced production of biobased, biodegradable, Poly(3-hydroxybutyrate) using an unexplored marine bacterium Pseudohalocynthiibacter aestuariivivens, isolated from highly polluted coastal environment. Bioresource Technology. 368, p. 128287. https://doi.org/10.1016/j.biortech.2022.128287

Author Correction: A HML6 endogenous retrovirus on chromosome 3 is upregulated in amyotrophic lateral sclerosis motor cortex
Jones, A.R., Iacoangeli, A., Adey, B.N., Bowles, H., Shatunov, A., Troakes, C., Garson, J.A., McCormick, A.L. and Al‑Chalabi, A. 2022. Author Correction: A HML6 endogenous retrovirus on chromosome 3 is upregulated in amyotrophic lateral sclerosis motor cortex. Scientific Reports. 12 14171. https://doi.org/10.1038/s41598-022-18488-y

Author Correction: A HML6 endogenous retrovirus on chromosome 3 is upregulated in amyotrophic lateral sclerosis motor cortex
Jones, Ashley R., Iacoangeli, Alfredo, Adey, Brett N., Bowles, Harry, Shatunov, Aleksey, Troakes, Claire, Garson, Jeremy A., McCormick, Adele L. and Al-Chalabi, Ammar 2022. Author Correction: A HML6 endogenous retrovirus on chromosome 3 is upregulated in amyotrophic lateral sclerosis motor cortex. Scientific Reports. 12 (1) 14171. https://doi.org/10.1038/s41598-022-18488-y

A HML6 endogenous retrovirus on chromosome 3 is upregulated in amyotrophic lateral sclerosis motor cortex.
Jones, A.R., Iacoangeli, A., Adey, B.N., Bowles, H., Shatunov, A, Troakes, C., Garson, J.A., McCormick, A.L. and Al‑Chalabi, A. 2021. A HML6 endogenous retrovirus on chromosome 3 is upregulated in amyotrophic lateral sclerosis motor cortex. Scientific Reports. 11 14283. https://doi.org/10.1038/s41598-021-93742-3

N-Acetylcysteine Nanocarriers Protect against Oxidative Stress in a Cellular Model of Parkinson’s Disease
Mursaleen, L., Noble, B., Chan, S.H.Y., Somavarapu, S. and Zariwala, M. 2020. N-Acetylcysteine Nanocarriers Protect against Oxidative Stress in a Cellular Model of Parkinson’s Disease. Antioxidants. 9 (7) 600. https://doi.org/10.3390/antiox9070600

Elevated microRNA expression could be diagnostic biomarker for PDAC
Mortoglou, M., Arisan, D., Ferreira, T., McCormick, A.L. and Uysal Onganer, P. 2020. Elevated microRNA expression could be diagnostic biomarker for PDAC. Pancreatology. 20 (8) e19. https://doi.org/10.1016/j.pan.2020.10.015

N-Acetylcysteine Nanocarriers Protect against Oxidative Stress in a Cellular Model of Parkinson's Disease
Mursaleen, Leah, Noble, Brendon, Chan, S., Somavarapu, Satyanarayana and Zariwala, M. 2020. N-Acetylcysteine Nanocarriers Protect against Oxidative Stress in a Cellular Model of Parkinson's Disease. Antioxidants. 9 (7), p. 600. https://doi.org/10.3390/antiox9070600

Populated Collagen Hydrogel and Polyhydroxyalkanoate Composites: Novel Matrices for Cartilage Repair and Regeneration?
De Pascale, C., Marcello, E., Getting, S.J., Roy, I. and Locke, I.C. Forthcoming. Populated Collagen Hydrogel and Polyhydroxyalkanoate Composites: Novel Matrices for Cartilage Repair and Regeneration? OARSI World Congress on Osteoarthritis . Toronto, Canada 29 2018 - 26 Apr 2019

Non-formal physical education influence on health related physical fitness of children
Sarkauskiene, Asta, Noble, Brendon, Kardeliene, Laimute and Noble, Brendon 2019. Non-formal physical education influence on health related physical fitness of children. SOCIETY. INTEGRATION. EDUCATION. Proceedings of the International Scientific Conference. 4, pp. 252-267. https://doi.org/10.17770/sie2019vol4.3865

Response to the Letter from Garcia-Montojo and colleagues concerning our paper entitled, Quantitative analysis of human endogenous retrovirus-K transcripts in postmortem premotor cortex fails to confirm elevated expression of HERV-K RNA in amyotrophic lateral sclerosis.
Garson, J.A., Usher, L., Al-Chalabi, A., Huggett, J., Day, E. and McCormick, A.L. 2019. Response to the Letter from Garcia-Montojo and colleagues concerning our paper entitled, Quantitative analysis of human endogenous retrovirus-K transcripts in postmortem premotor cortex fails to confirm elevated expression of HERV-K RNA in amyotrophic lateral sclerosis. Acta Neuropathologica Communications. 7 102. https://doi.org/10.1186/s40478-019-0756-9

Esterase Cleavable 2D Assemblies of Magnetic Iron Oxide Nanocubes: Exploiting Enzymatic Polymer Disassembling to Improve Magnetic Hyperthermia Heat Losses
Avugadda, S.K., Materia, M.E., Nigmatullin, R., Cabrera, D., Marotta, R., Cabada, T.F., Marcello, E., Nitti, S., Artés-Ibañez, E.J., Basnett, P., Wilhelm, C., Teran, F.J., Roy, I. and Pellegrino, T. 2019. Esterase Cleavable 2D Assemblies of Magnetic Iron Oxide Nanocubes: Exploiting Enzymatic Polymer Disassembling to Improve Magnetic Hyperthermia Heat Losses. Chemistry of Materials. 31 (15), pp. 5450-5463. https://doi.org/10.1021/acs.chemmater.9b00728

Techniques for the study of apoptosis in bone
Mann, V. and Noble, B. 2019. Techniques for the study of apoptosis in bone. in: Idris, A.I. (ed.) Bone research protocols Springer. pp. 451-465

Quantitative analysis of Human Endogenous Retrovirus-K transcripts in postmortem premotor cortex fails to confirm elevated expression of HERV-K RNA in amyotrophic lateral sclerosis
Garson, J.A., Usher, L., Al-Chalabi, A., Huggett, J., Day, E.F. and McCormick, A.L. 2019. Quantitative analysis of Human Endogenous Retrovirus-K transcripts in postmortem premotor cortex fails to confirm elevated expression of HERV-K RNA in amyotrophic lateral sclerosis. Acta Neuropathologica Communications. 7 45. https://doi.org/10.1186/s40478-019-0698-2

Biosynthesis and characterization of a novel, biocompatible medium chain length polyhydroxyalkanoate by Pseudomonas mendocina CH50 using coconut oil as the carbon source
Basnett, P., Marcello, E., Lukasiewicz, B., Panchal, B., Nigmatullin, R., Knowles, J.C. and Roy, I. 2018. Biosynthesis and characterization of a novel, biocompatible medium chain length polyhydroxyalkanoate by Pseudomonas mendocina CH50 using coconut oil as the carbon source. Journal of Materials Science: Materials in Medicine. 29, p. 179 179. https://doi.org/10.1007/s10856-018-6183-9

Production of a novel medium chain length Poly(3-hydroxyalkanoate) using unprocessed biodiesel waste and its evaluation as a tissue engineering scaffold
Basnett, P., Lukasiewicz, B., Marcello, E., Kaur, H., Knowles, J.C. and Roy, I. 2017. Production of a novel medium chain length Poly(3-hydroxyalkanoate) using unprocessed biodiesel waste and its evaluation as a tissue engineering scaffold. Microbial Biotechnology. 10 (6), pp. 1384-1399. https://doi.org/10.1111/1751-7915.12782

Is elite sport a driver for medical advance? ; Ar didelio meistriškumo sportas skatina medicinos pažangą?
Noble, Brendon 2016. Is elite sport a driver for medical advance? ; Ar didelio meistriškumo sportas skatina medicinos pažangą? Sport Science. 1 (86), pp. 2-7. https://doi.org/10.15823/sm.2016.1

Correction: Evidence for Reduced Drug Susceptibility without Emergence of Major Protease Mutations following Protease Inhibitor Monotherapy Failure in the SARA Trial.
Sutherland, K.A., Parry, C.M., McCormick, A.L., Kapaata, A., Lyagoba, F., Kaleebu, P., Gilks, C.F., Goodall, R., Spyer, M., Kityo, C., Pillay, D., Gupta, R.K. and DART Virology Group 2016. Correction: Evidence for Reduced Drug Susceptibility without Emergence of Major Protease Mutations following Protease Inhibitor Monotherapy Failure in the SARA Trial. PLoS ONE. 11 (6) e0157094. https://doi.org/10.1371/journal.pone.0157094

Gag-Protease Sequence Evolution Following Protease Inhibitor Monotherapy Treatment Failure in HIV-1 Viruses Circulating in East Africa.
Sutherland, K.A., Goodall, R.L., McCormick, A.L., Kapaata, A., Lyagoba, F., Kaleebu, P., Thiltgen, G., Gilks, C.F., Spyer, M., Kityo, C., Pillay, D., Dunn, D. and Gupta, R.K. 2015. Gag-Protease Sequence Evolution Following Protease Inhibitor Monotherapy Treatment Failure in HIV-1 Viruses Circulating in East Africa. AIDS Research and Human Retroviruses. 31 (10), pp. 1032-1037. https://doi.org/10.1089/aid.2015.0138

Evidence for Reduced Drug Susceptibility without Emergence of Major Protease Mutations following Protease Inhibitor Monotherapy Failure in the SARA Trial
Sutherland, K.A., Parry, C.M., McCormick, A.L., Kapaata, A., Lyagoba, F., Kaleebu, P., Gilks, C.F., Goodall, R., Spyer, M., Kityo, C., Pillay, D., Gupta, R.K. and DART Virology Group 2015. Evidence for Reduced Drug Susceptibility without Emergence of Major Protease Mutations following Protease Inhibitor Monotherapy Failure in the SARA Trial. PLoS ONE. 10 (9) e0137834. https://doi.org/10.1371/journal.pone.0137834

IL28B genotype predicts response to chronic hepatitis C triple therapy with telaprevir or boceprevir in treatment naïve and treatment-experienced patients other than prior partial- and null-responders
Calisti, G., Tavares, A., Macartney, M.J., McCormick, A.L., Labbett, W., Jacobs, M., Dusheiko, G., Rosenberg, W.M. and Haque, T. 2015. IL28B genotype predicts response to chronic hepatitis C triple therapy with telaprevir or boceprevir in treatment naïve and treatment-experienced patients other than prior partial- and null-responders. SpringerPlus. 4 (1). https://doi.org/10.1186/s40064-015-1137-x

Evaluation of sequencing of HCV core/E1, NS5A and NS5B as a genotype predictive tool in comparison with commercial assays targeting 5′UTR
McCormick, A.L., Macartney, M.J., Abdi-Abshir, I., Labbett, W., Smith, C., Irish, D., Webster, D.P. and Haque, T. 2015. Evaluation of sequencing of HCV core/E1, NS5A and NS5B as a genotype predictive tool in comparison with commercial assays targeting 5′UTR. Journal of Clinical Virology. 66 (May), pp. 56-59. https://doi.org/10.1016/j.jcv.2015.03.006

Ultra-deep sequencing provides insights into the virology of hepatitis C super-infections in a case of three sequential infections with different genotypes
Chung, E., Ferns, R.B., He, M., Rigatti, R., Grant, P., McCormick, A.L., Bhagani, S., Webster, D.P., Nastouli, E. and Waters, L.J. 2015. Ultra-deep sequencing provides insights into the virology of hepatitis C super-infections in a case of three sequential infections with different genotypes. Journal of Clinical Virology. 70 (Sept), pp. 63-66. https://doi.org/10.1016/j.jcv.2015.06.105

The utility of genotypic tropism testing in clinical practice
Wyatt, H., Herman, O., Macartney, M.J., Conibear, T., Garcia-Diaz, A., Booth, C., McCormick, A.L., Smith, C., Johnson, M., Irish, D. and Webster, D. 2015. The utility of genotypic tropism testing in clinical practice. International Journal of STD and AIDS. 26 (8), pp. 593-594. https://doi.org/10.1177/0956462414546917

Phenotypic and genotypic analyses to guide selection of reverse transcriptase inhibitors in second-line HIV therapy following extended virological failure in Uganda
R. L. Goodall, D. T. Dunn, T. Pattery, A. van Cauwenberge, P. Nkurunziza, P. Awio, N. Ndembi, P. Munderi, C. Kityo, C. F. Gilks, P. Kaleebu, D. Pillay, P. Kaleebu, D. Pillay, P. Awio, M. Chirara, D. Dunn, D. M. Gibb, C. Gilks, R. Goodall, A. Kapaata, M. Katuramur, F. Lyagoba, R. Magala, B. Magambo, K. Mataruka, A.L. McCormick, L. Mugarura, T. Musunga, M. Nabankkema, J. Nkalubo, P. Nkurunziza, C. Parry, V. Robertson, M. Spyer, D. Yirrell, H. Grosskurth, P. Munderi, G. Kabuye, D. Nsibambi, R. Kasirye, E. Zalwango, M. Nakazibwe, B. Kikaire, G. Nassuna, R. Massa, K. Fadhiru, M. Namyalo, A. Zalwango, L. Generous and P. Khauka 2014. Phenotypic and genotypic analyses to guide selection of reverse transcriptase inhibitors in second-line HIV therapy following extended virological failure in Uganda. Journal of Antimicrobial Chemotherapy. 69 (7), pp. 1938-1944. https://doi.org/10.1093/jac/dku052

Feasibility of testing and detection of HIV-1 drug resistance in proviral DNA
Booth, C., McCormick, A.L., Garcia-Diaz, A., Macartney, M., Youle, M., Johnson, M. and Webster, D. 2014. Feasibility of testing and detection of HIV-1 drug resistance in proviral DNA. BMC Infectious Diseases. 14 (Supplement 4) O25. https://doi.org/10.1186/1471-2334-14-s4-o25

Analysis of transmitted HIV-1 drug resistance using 454 ultra-deep-sequencing and the DeepChek(®)-HIV system.
Garcia-Diaz, A., McCormick, A.L., Booth, C., Gonzalez, D., Sayada, C., Haque, T., Johnson, M. and Webster, D. 2014. Analysis of transmitted HIV-1 drug resistance using 454 ultra-deep-sequencing and the DeepChek(®)-HIV system. Journal of the International AIDS Society. 17 (Suppl 3) 19752. https://doi.org/10.7448/ias.17.4.19752

Telaprevir or boceprevir based therapy for chronic hepatitis C infection: Development of resistance-associated variants in treatment failure
Macartney, M.J., Irish, D., Bridge, S.H., Garcia-Diaz, A., Booth, C., McCormick, A.L., Labbett, W., Smith, C., Velazquez, C., Tanwar, S., Trembling, P., Jacobs, M., Dusheiko, G., Rosenberg, W.M. and Haque, T. 2014. Telaprevir or boceprevir based therapy for chronic hepatitis C infection: Development of resistance-associated variants in treatment failure. Antiviral Research. 105, pp. 112-7. https://doi.org/10.1016/j.antiviral.2014.02.019

Prevalence of baseline polymorphisms for potential resistance to NS5A inhibitors in drug-naive individuals infected with hepatitis C genotypes 1–4
McCormick, A.L., Wang, L., Garcia-Diaz, A., Macartney, M.J., Webster, D.P. and Haque, T. 2014. Prevalence of baseline polymorphisms for potential resistance to NS5A inhibitors in drug-naive individuals infected with hepatitis C genotypes 1–4 . Antiviral Therapy. 20 (1), pp. 81-85. https://doi.org/10.3851/IMP2763

The utility of different bioinformatics algorithms for genotypic HIV-1 tropism testing in a large clinical cohort with multiple subtypes
Bartlett, A., Macartney, M.J., Conibear, T., Feyertag, F., Smith, C., Johnson, M., Hyams, C., Garcia-Diaz, A., McCormick, A.L., Booth, C., Robertson, D. and Webster, D.P. 2014. The utility of different bioinformatics algorithms for genotypic HIV-1 tropism testing in a large clinical cohort with multiple subtypes. AIDS. 28 (11), pp. 1611-7. https://doi.org/10.1097/QAD.0000000000000288

Baseline drug-resistance mutations are detectable in HCV genes NS3 and NS5A but not NS5B in acute and chronic HIV-coinfected patients
McCormick, A.L., Moynihan, L., Macartney, M.J., Garcia-Diaz, A., Smith, C., Johnson, M., Rodger, A.J., Bhagani, S., Haque, T. and Webster, D. 2014. Baseline drug-resistance mutations are detectable in HCV genes NS3 and NS5A but not NS5B in acute and chronic HIV-coinfected patients. Antiviral Therapy. 20 (3), p. 2015. https://doi.org/10.3851/IMP2871

3-D printouts of the tracheobronchial tree generated from CT images as an aid to management in a case of tracheobronchial chondromalacia caused by relapsing polychondritis
Tam, Matthew D.B.S., Laycock, Stephen, Jayne, David, Babar, Judith and Noble, Brendon 2013. 3-D printouts of the tracheobronchial tree generated from CT images as an aid to management in a case of tracheobronchial chondromalacia caused by relapsing polychondritis. Journal of Radiology Case Reports. 7 (8), pp. 34-43. https://doi.org/10.3941/jrcr.v7i8.1390

Osteocyte apoptosis
Jilka, Robert L., Noble, Brendon and Weinstein, Robert S. 2013. Osteocyte apoptosis. Bone. 54 (2), pp. 264-271. https://doi.org/10.1016/j.bone.2012.11.038

Directed osteogenic differentiation of human mesenchymal stem/precursor cells on silicate substituted calcium phosphate
Cameron, Kate, Travers, Paul, Chander, Chaman, Buckland, Tom, Campion, Charlie and Noble, Brendon 2013. Directed osteogenic differentiation of human mesenchymal stem/precursor cells on silicate substituted calcium phosphate. Journal of Biomedical Materials Research Part A. 101A (1), pp. 13-22. https://doi.org/10.1002/jbm.a.34261

Evaluation of the Roche prototype 454 HIV-1 ultradeep sequencingdrug resistance assay in a routine diagnostic laboratory
Garcia-Diaz, A., Guerrero-Ramos, A., McCormick, A.L., Macartney, M.J., Conibear, T., Johnson, M., Haque, T. and Webster, D.P. 2013. Evaluation of the Roche prototype 454 HIV-1 ultradeep sequencingdrug resistance assay in a routine diagnostic laboratory. Journal of Clinical Virology. 58 (2), pp. 468-473. https://doi.org/10.1016/j.jcv.2013.07.009

Assessment of a preclinical model for studying the survival and engraftment of human stem cell derived osteogenic cell populations following orthotopic implantation
Tremoleda, J.L., Khan, N.S., Mann, V., Racey, S.N., Martin, A.J., Simpson, A.H.W.R. and Noble, B. 2012. Assessment of a preclinical model for studying the survival and engraftment of human stem cell derived osteogenic cell populations following orthotopic implantation. Journal of Musculoskeletal Neuronal Interactions. 12 (4), pp. 241-253.

Techniques for the Study of Apoptosis in Bone
Riahi, Sudeh, Noble, Brendon and Noble, B. 2011. Techniques for the Study of Apoptosis in Bone. in: Miep H. Helfrich and Stuart H. Ralston (ed.) Bone Research Protocols. 2nd edition Springer Nature. pp. 335-349

Collaborative project to co-ordinate care for patients with dementia.
Kennerley, D., Bolas, R., Bourne, J., Branson, K., Cavenagh, P., Collins, G., Coveney, N., Day, N., Hardman, M., Hayter, S., Fenner, P., Jones, J., Jordan, S., Noble, B., Osbourne, S., Smith, C. and Wigens, L. 2011. Collaborative project to co-ordinate care for patients with dementia. Nursing Management. 18 (2), pp. 27-31. https://doi.org/10.7748/nm2011.05.18.2.27.c8484

Laser microdissection and pressure catapulting of single human motor neurons for RNA editing analysis
Sun, H., Raja, A., O’Connell, M.A., Mann, V., Noble, B. and Keegan, L.P. 2011. Laser microdissection and pressure catapulting of single human motor neurons for RNA editing analysis. in: RNA and DNA Editing: Methods and Protocols Humana Press. pp. 75–87

Blunting of adaptive responses to resistance exercise training in women over 75y
Greig, C.A., Gray, C., Rankin, D., Young, A., Mann, V., Noble, B. and Atherton, P.J. 2011. Blunting of adaptive responses to resistance exercise training in women over 75y. Experimental Gerontology. 46 (11), pp. 884-890. https://doi.org/10.1016/j.exger.2011.07.010

Impact of the N348I Mutation in HIV-1 Reverse Transcriptase on Nonnucleoside Reverse Transcriptase Inhibitor Resistance in Non-Subtype B HIV-1
McCormick, A.L., Parry, C.M., Crombe, A., Goodall, R.L., Gupta, R.K., Kaleebu, P., Kityo, C., Chirara, M., Towers, G.J. and Pillay, D. 2011. Impact of the N348I Mutation in HIV-1 Reverse Transcriptase on Nonnucleoside Reverse Transcriptase Inhibitor Resistance in Non-Subtype B HIV-1. Antimicrobial Agents and Chemotherapy. 55 (4), pp. 1806-1809. https://doi.org/10.1128/AAC.01197-10

A novel method for the directed osteogenic differentiation of human mesenchymal stem/precursor cells
B. Noble, C. Chander, T. Buckland and K.R. Cameron 2010. A novel method for the directed osteogenic differentiation of human mesenchymal stem/precursor cells. Bone. 47 (Supp.1), p. S128. https://doi.org/10.1016/j.bone.2010.04.283

Full length HIV-1 Gag determines protease inhibitor susceptibility within in vitro assays
Gupta, R.K., Kohli, A., McCormick, A.L., Towers, G.J., Pillay, D. and Parry, C.M. 2010. Full length HIV-1 Gag determines protease inhibitor susceptibility within in vitro assays. AIDS. 24 (11), p. 1651–1655. https://doi.org/10.1097/QAD.0b013e3283398216

Lack of Minority K65RResistant Viral Populations Detected After Repeated Treatment Interruptions of Tenofovir/Zidovudine and Lamivudine in a Resource-Limited Setting
McCormick, A.L., Goodall, R.L., Joyce, A., Ndembi, N., Chirara, M., Katunduk, P., Walker, A.S., Yirrell, D.L., Gilks, C.F. and Pillay, D. 2010. Lack of Minority K65RResistant Viral Populations Detected After Repeated Treatment Interruptions of Tenofovir/Zidovudine and Lamivudine in a Resource-Limited Setting. Journal of Acquired Immune Deficiency Syndromes. 54 (2), pp. 215-216. https://doi.org/10.1097/QAI.0b013e3181cc1058

Viral Rebound and Emergence of Drug Resistance in the Absence of Viral Load Testing: A Randomized Comparison between Zidovudine-Lamivudine plus Nevirapine and Zidovudine-Lamivudine plus Abacavir
Ndembi, N., Goodall, R.L., Dunn, D.T., McCormick, A.L., Burke, A., Lyagoba, F., Munderi, P., Katundu, P., Kityo, C., Robertson, V., Yirrell, D.L., Walker, A.S., Gibb, D.M., Gilks, C.F., Kaleebu, P. and Pillay, D. 2010. Viral Rebound and Emergence of Drug Resistance in the Absence of Viral Load Testing: A Randomized Comparison between Zidovudine-Lamivudine plus Nevirapine and Zidovudine-Lamivudine plus Abacavir. The Journal of Infectious Diseases. 201 (1), pp. 106-113. https://doi.org/10.1086/648590

Development of stem cell carriers for bone regeneration
Hou, Q.P., Spadaccino, A., Hughes, O., Dauphin, D.S. and Noble, B.S. 2009. Development of stem cell carriers for bone regeneration. European Cells and Materials. 18 (Supp. 1), p. 41.

The role of estrogen in the repair of osteocytes following physical injury in vitro
V. Mann, L. Kitto and B. Noble 2009. The role of estrogen in the repair of osteocytes following physical injury in vitro. Bone. 44 (Supp.1), p. S62. https://doi.org/10.1016/j.bone.2009.01.028

TGF β 3 and loading increases osteocyte survival in human cancellous bone cultured ex vivo
Simpson, Angharad E., Stoddart, Martin J., Davies, Catrin M., Jähn, Katharina, Furlong, Pamela I., Gasser, Jürg A., Jones, David B., Noble, Brendon S. and Richards, Robert G. 2009. TGF β 3 and loading increases osteocyte survival in human cancellous bone cultured ex vivo. Cell Biochemistry & Function. 27 (1), pp. 23-29. https://doi.org/10.1002/cbf.1529

The biology of osteocytes
Kogianni, Giolanta and Noble, Brendon S. 2009. The biology of osteocytes. Current Osteoporosis Reports. 5, pp. 81-86. https://doi.org/10.1007/s11914-007-0007-z

The role of the osteocyte in bone turnover
Brendon Noble 2008. The role of the osteocyte in bone turnover. Bone. 43 (Supp. 1), p. S22. https://doi.org/10.1016/j.bone.2008.07.258

The osteocyte lineage
Noble, Brendon S. 2008. The osteocyte lineage. Archives of Biochemistry and Biophysics. 473 (2), pp. 106-111. https://doi.org/10.1016/j.abb.2008.04.009

Apoptotic Bodies Convey Activity Capable of Initiating Osteoclastogenesis and Localized Bone Destruction
Kogianni, Giolanta, Mann, Val and Noble, Brendon S. 2008. Apoptotic Bodies Convey Activity Capable of Initiating Osteoclastogenesis and Localized Bone Destruction. Journal of Bone and Mineral Research. 23 (6), pp. 915-927. https://doi.org/10.1359/jbmr.080207

Bone tissue formation from human embryonic stem cells in vivo
Tremoleda, Jordi, Forsyth, Nicholas, Khan, Nusrat, Wojtacha, Davina, Christodoulou, Ioannis, Tye, B.J., Racey, Seth, Collinshaw, S., Sottile, Virginie, Thomson, Alison, Simpson, Hamish, Noble, Brendon and McWhir, Jim 2008. Bone tissue formation from human embryonic stem cells in vivo. Cloning and Stem Cells. 10 (1), pp. 119-132. https://doi.org/10.1089/clo.2007.0r36

Ex Vivo bone formation in bovine trabecular bone cultured in a dynamic 3D bioreactor is enhanced by compressive mechanical strain
David, Valentin, Guignandon, Alain, Martin, Aline, Malaval, Luc, Lafage-Proust, Marie-Hélène, Rattner, Aline, Mann, Val, Noble, Brendon, Jones, David, B. and Vico, Laurence 2008. Ex Vivo bone formation in bovine trabecular bone cultured in a dynamic 3D bioreactor is enhanced by compressive mechanical strain. Tissue Engineering Part A. 14 (1), pp. 117-126. https://doi.org/10.1089/ten.a.2007.0051

Quantification of reverse transcriptase in ALS and elimination of a novel retroviral candidate
McCormick, A.L., Brown, R.H., Cudkowicz, M.E., Al-Chalabi, A. and Garson, J.A. 2008. Quantification of reverse transcriptase in ALS and elimination of a novel retroviral candidate. Neurology. 70 (4), pp. 278-283. https://doi.org/10.1212/01.wnl.0000297552.13219.b4

The antioxidant effect of estrogen and Selective Estrogen Receptor Modulators in the inhibition of osteocyte apoptosis in vitro
Mann, Val, Huber, Christene, Kogianni, Giolanta, Collins, Frances and Noble, Brendon 2007. The antioxidant effect of estrogen and Selective Estrogen Receptor Modulators in the inhibition of osteocyte apoptosis in vitro. Bone. 40 (3), pp. 674-684. https://doi.org/10.1016/j.bone.2006.10.014

Selective estrogen receptor modulator inhibits osteocyte apoptosis during abrupt estrogen withdrawal: Implications for bone quality maintenance
Huber, C., Collishaw, S., Mosley, J.R., Reeve, J. and Noble, B.S. 2007. Selective estrogen receptor modulator inhibits osteocyte apoptosis during abrupt estrogen withdrawal: Implications for bone quality maintenance. Calcified Tissue International. 81, pp. 139-144. https://doi.org/10.1007/s00223-007-9049-6

Skeletal muscle IGF-I isoform expression in healthy women after isometric exercise
Greig, Carolyn A., Hameed, Mahjabeen, Young, Archie, Goldspink, Geoffrey and Noble, Brendon 2006. Skeletal muscle IGF-I isoform expression in healthy women after isometric exercise. Growth Hormone & IGF Research. 16 (5-6), pp. 373-376. https://doi.org/10.1016/j.ghir.2006.09.005

Physiologic Oxygen Enhances Human Embryonic Stem Cell Clonal Recovery and Reduces Chromosomal Abnormalities
Forsyth, Nicholas R., Musio, Antonio, Vezzoni, Paolo, Simpson, A. Hamish R.W., Noble, Brendon S. and McWhir, Jim 2006. Physiologic Oxygen Enhances Human Embryonic Stem Cell Clonal Recovery and Reduces Chromosomal Abnormalities. Cloning and Stem Cells. 8 (1), pp. 16-23. https://doi.org/10.1089/clo.2006.8.16

The role of growth factors and related agents in accelerating fracture healing
A. H. R. W. Simpson, L. Mills and Noble, B. 2006. The role of growth factors and related agents in accelerating fracture healing. The Journal of Bone and Joint Surgery. British volume. 88-B (6), pp. 701 - 705. https://doi.org/10.1302/0301-620x.88b6.17524

The influence of mechanical stimulation on osteocyte apoptosis and bone viability in human trabecular bone
Mann, V., Huber, C., Kogianni, G., Jones, D. and Noble, B. 2006. The influence of mechanical stimulation on osteocyte apoptosis and bone viability in human trabecular bone. Journal of Musculoskeletal Neuronal Interactions. 6 (4), pp. 408-417.

Stem cells and orthopaedic disease
McWhir, J. and Noble, B. 2005. Stem cells and orthopaedic disease. European Cells and Materials. 10 (SUPPL.2), p. 8.

Microdamage and apoptosis
Noble, B. 2005. Microdamage and apoptosis. European Journal of Morphology. 42 (1-2), pp. 91-98. https://doi.org/10.1080/09243860500096248

An interferon gamma-gp120 fusion delivered as a DNA vaccine induces enhanced priming
Nimal, S., McCormick, A.L., Thomas, M.S. and Heath, A.W. 2005. An interferon gamma-gp120 fusion delivered as a DNA vaccine induces enhanced priming. Vaccine. 23 (10), pp. 3984-3990. https://doi.org/10.1016/j.vaccine.2005.01.160

Fas/CD95 is associated with glucocorticoid-induced osteocyte apoptosis
Kogianni, G., Mann, V., Ebetino, F., Nuttall, M., Nijweide, P., Simpson, H. and Noble, B. 2004. Fas/CD95 is associated with glucocorticoid-induced osteocyte apoptosis. Life Sciences. 75 (24), pp. 2879-2895. https://doi.org/10.1016/j.lfs.2004.04.048

CD40 antibody as an adjuvant induces enhanced T cell responses
Carlring, J., Barr, T.A., McCormick, A.L. and Heath, A.W. 2004. CD40 antibody as an adjuvant induces enhanced T cell responses. Vaccine. 22 (25-26), p. 3323–3328. https://doi.org/10.1016/j.vaccine.2004.02.043

Compartmentalized megakaryocyte death generates functional platelets committed to caspase-independent death
Clarke, Murray C.H., Savill, John, Jones, David B., Noble, Brendon S. and Brown, Simon B. 2003. Compartmentalized megakaryocyte death generates functional platelets committed to caspase-independent death. in: Bone Research Protocols Springer. pp. 225-236

Mechanical stimulation & cell death-shaping our bones
Noble, B. 2003. Mechanical stimulation & cell death-shaping our bones. European Cells and Materials. 5 (Suppl.2), p. 25.

Bone microdamage and cell apoptosis
Noble, B., Alini, M. and Richards, R.G. 2003. Bone microdamage and cell apoptosis. European Cells and Materials. 6, pp. 46-55.

A bone fluid flow hypothesis for muscle pump-driven capillary filtration: II Proposed role for exercise in erodible scaffold implant incorporation
Winet, H., Noble, B. and Jones, D. 2003. A bone fluid flow hypothesis for muscle pump-driven capillary filtration: II Proposed role for exercise in erodible scaffold implant incorporation. European Cells and Materials. 6. https://doi.org/10.22203/ecm.v006a01

Mechanical loading: Biphasic osteocyte survival and targeting of osteoclasts for bone destruction in rat cortical bone
Noble, B.S., Peet, N., Stevens, H.Y., Brabbs, A., Mosley, J.R., Reilly, G.C., Reeve, J., Skerry, T.M. and Lanyon, L.E. 2003. Mechanical loading: Biphasic osteocyte survival and targeting of osteoclasts for bone destruction in rat cortical bone. American Journal of Physiology: Cell Physiology. 284 (4), pp. C934-C943. https://doi.org/10.1152/ajpcell.00234.2002

A potent adjuvant effect of CD40 antibody attached to antigen
Barr, T.A., McCormick, A.L., Carlring, J. and Heath, A.W. 2003. A potent adjuvant effect of CD40 antibody attached to antigen. Immunology. 109 (1), pp. 87-92. https://doi.org/10.1046/j.1365-2567.2003.01634.x

The effect of in vivo mechanical loading on estrogen receptor α expression in rat ulnar osteocytes
Ehrlich, P.J., Noble, B.S., Jessop, H.L., Stevens, H.Y., Mosley, J.R. and Lanyon, L.E. 2002. The effect of in vivo mechanical loading on estrogen receptor α expression in rat ulnar osteocytes. Journal of Bone and Mineral Research. 17 (9), pp. 1646-1655. https://doi.org/10.1359/jbmr.2002.17.9.1646

Osteocyte lacunar occupancy in the femoral neck cortex: An association with cortical remodeling in hip fracture cases and controls
Power, J., Noble, B.S., Loveridge, N., Bell, K.L., Rushton, N. and Reeve, J. 2001. Osteocyte lacunar occupancy in the femoral neck cortex: An association with cortical remodeling in hip fracture cases and controls. Calcified Tissue International. 69 (1), pp. 13-19. https://doi.org/10.1007/s00223-001-0013-6

Immunization with an Interferon-g–gp120 Fusion Protein Induces Enhanced Immune Responses to Human Immunodeficiency Virus gp120
McCormick, A.L., Thomas, M.S. and Heath, A.W. 2001. Immunization with an Interferon-g–gp120 Fusion Protein Induces Enhanced Immune Responses to Human Immunodeficiency Virus gp120. The Journal of Infectious Diseases. 184 (11), pp. 1423-1430. https://doi.org/10.1086/324371

Osteocyte function, osteocyte death and bone fracture resistance
Noble, Brendon S. and Reeve, Jonathan 2000. Osteocyte function, osteocyte death and bone fracture resistance. Molecular and Cellular Endocrinology. 159 (1-2), pp. 7-13. https://doi.org/10.1016/s0303-7207(99)00174-4

Bcl-2, tissue transglutaminase and p53 protein expression in the apoptotic cascade in ribs of premature infants
Stevens, H.Y., Reeve, J. and Noble, B.S. 2000. Bcl-2, tissue transglutaminase and p53 protein expression in the apoptotic cascade in ribs of premature infants. Journal of Anatomy. 196 (2). https://doi.org/10.1017/s0021878299005889

Expression and functional role of nitric oxide synthase isoforms in human osteoblast-like cells
H. MacPherson, B.S. Noble and S.H. Ralston 1999. Expression and functional role of nitric oxide synthase isoforms in human osteoblast-like cells. Bone. 24 (3), pp. 179-185. https://doi.org/10.1016/s8756-3282(98)00173-2

Characterization of 11β-hydroxysteroid dehydrogenase activity and corticosteroid receptor expression in human osteosarcoma cell lines
Bland, R., Worker, C.A., Noble, B.S., Eyre, L.J., Bujalska, J.I., Sheppard, M.C., Stewart, P.M. and Hewison, M. 1999. Characterization of 11β-hydroxysteroid dehydrogenase activity and corticosteroid receptor expression in human osteosarcoma cell lines. Journal of Endocrinology. 161 (3), pp. 455-464. https://doi.org/10.1677/joe.0.1610455

Gag Determinants of Fitness and Drug Susceptibility in Protease Inhibitor-Resistant Human Immunodeficiency Virus Type 1
Parry, C.M., Kohli, A., Boinett, C.J., Towers, G.J., McCormick, A.L. and Pillay, D. 1999. Gag Determinants of Fitness and Drug Susceptibility in Protease Inhibitor-Resistant Human Immunodeficiency Virus Type 1. Journal of Virology. 83 (18), pp. 9094-9101. https://doi.org/10.1128/JVI.02356-08

Cell Surface Expression of CD154 Inhibits Alloantibody Responses: A Mechanism for the Prevention of Autoimmune Responses against Activated T Cells?
McCormick, A.L., Santos-Argumedo, L., Thomas, M.S. and Heath, A.W. 1999. Cell Surface Expression of CD154 Inhibits Alloantibody Responses: A Mechanism for the Prevention of Autoimmune Responses against Activated T Cells? Cellular Immunology. 195 (2), pp. 157-161. https://doi.org/10.1006/cimm.1999.1528

Effect of estrogen suppression on the mineralization density of iliac crest biopsies in young women as assessed by backscattered electron imaging
A. Boyde, J.E. Compston, J. Reeve, K.L. Bell, B.S. Noble, S.J. Jones and N. Loveridge 1998. Effect of estrogen suppression on the mineralization density of iliac crest biopsies in young women as assessed by backscattered electron imaging. Bone. 22 (3), pp. 241-250. https://doi.org/10.1016/s8756-3282(97)00275-5

The role of estrogen in the control of rat osteocyte apoptosis
Tomkinson, A., Gevers, E.F., Wit, J.M., Reeve, J. and Noble, B.S. 1998. The role of estrogen in the control of rat osteocyte apoptosis. Journal of Bone and Mineral Research. 13 (8), pp. 1243-1250. https://doi.org/10.1359/jbmr.1998.13.8.1243

Identification of apoptotic changes in osteocytes in normal and pathological human bone
B.S. Noble, H. Stevens, N. Loveridge and J. Reeve 1997. Identification of apoptotic changes in osteocytes in normal and pathological human bone. Bone. 20 (3), pp. 273-282. https://doi.org/10.1016/s8756-3282(96)00365-1

The death of osteocytes via apoptosis accompanies estrogen withdrawal in human bone
Tomkinson, A., Reeve, J., Shaw, R.W. and Noble, B.S. 1997. The death of osteocytes via apoptosis accompanies estrogen withdrawal in human bone. Journal of Clinical Endocrinology and Metabolism. 82 (9), pp. 3128-3135. https://doi.org/10.1210/jc.82.9.3128

Enhancement of immunogenicity of recombinant antigens by production of a cytokine-antigen fusion protein for vaccination
McCormick, A.L., Thomas, M.S. and Heath, A.W. 1997. Enhancement of immunogenicity of recombinant antigens by production of a cytokine-antigen fusion protein for vaccination. Biochemical Society Transactions. 25, p. 297S. https://doi.org/10.1042/bst025297s

O7. Does apoptosis play a role in osteocyte function?
B.S. Noble, H. Stevens, J. Reeve and N. Loveridge 1996. O7. Does apoptosis play a role in osteocyte function? Bone. 19 (6), p. 686. https://doi.org/10.1016/s8756-3282(97)84303-7

Dextran sulfate promotes the rapid aggregation of porcine bone-marrow stromal cells
B.S. Noble, V. Dean, N. Loveridge and B.M. Thomson 1995. Dextran sulfate promotes the rapid aggregation of porcine bone-marrow stromal cells. Bone. 17 (4), pp. 375-382. https://doi.org/10.1016/s8756-3282(95)00247-2

Apoptosis in growing rat bone: preliminary studies
B.S. Noble, J. Milne and N. Loveridge 1995. Apoptosis in growing rat bone: preliminary studies. Bone. 16 (6), p. 689. https://doi.org/10.1016/8756-3282(95)91680-6

Differential responses of human tumour cells to polyunsaturated fatty acids: Stimulation of proliferation of a colon tumour cell line by docosahexaenoic acid
McMillan, D.N., Heys, S.D., Murray, A.W., Noble, B.S., Purasiri, P., Deehan, D.J., Eremin, O. and Noble, B. 1995. Differential responses of human tumour cells to polyunsaturated fatty acids: Stimulation of proliferation of a colon tumour cell line by docosahexaenoic acid. International Journal of Oncology. 7 (4), pp. 927-933.

The differentiation of a potential mesenchymal stem cell population within ovine bone marrow
Jessop, H.L., Noble, B.S. and Cryer, A. 1994. The differentiation of a potential mesenchymal stem cell population within ovine bone marrow. Biochemical Society Transactions. 22 (3), p. 248S. https://doi.org/10.1042/bst022248s

P8. Bone marrow stromal cells separated by buoyant density: an initial characterisation
Noble, B.S., Rucklidge, G.J. and Thomson, B.M. 1994. P8. Bone marrow stromal cells separated by buoyant density: an initial characterisation. Bone. 15 (2), p. 232. https://doi.org/10.1016/8756-3282(94)90742-0

P12. Dextran sulphate promotes stromal cell aggregation and initiates type II collagen production
B.M. Thomson, V. Dean, B. Noble and N. Loveridge 1994. P12. Dextran sulphate promotes stromal cell aggregation and initiates type II collagen production. Bone. 15 (1), p. 120. https://doi.org/10.1016/8756-3282(94)90935-0

Control of longitudinal growth: The role of nutrition
Loveridge, N. and Noble, B.S. 1994. Control of longitudinal growth: The role of nutrition. European Journal of Clinical Nutrition. 48 (2), pp. 75-84.

Calcitonin gene related peptide stimulates differentiation of neonatal rat myogenic cultures
Noble, B.S., McMillan, D.N. and Maltin, C.A. 1993. Calcitonin gene related peptide stimulates differentiation of neonatal rat myogenic cultures. Growth Regulation. 3 (4), pp. 245-248.

Visualisation and selective elimination of a subpopulation of mitogen-responsive bone marrow stromal cells using bromodeoxyuridine and photo-induced cell killing
B.M. Thomson, V. Dean, C. Farquharson and B.S. Noble 1993. Visualisation and selective elimination of a subpopulation of mitogen-responsive bone marrow stromal cells using bromodeoxyuridine and photo-induced cell killing. Bone. 14 (5), pp. 779-786. https://doi.org/10.1016/8756-3282(93)90210-2

The effect of the beta-adrenergic agonist clenbuterol on growth and protein metabolism in rat muscle cell cultures
McMillan, D.N., Noble, B.S. and Maltin, C.A. 1992. The effect of the beta-adrenergic agonist clenbuterol on growth and protein metabolism in rat muscle cell cultures. Journal of Animal Science. 70 (10), p. 3014–3023. https://doi.org/10.2527/1992.70103014x

Effects of the cyclo-oxygenase inhibitor, fenbufen, on clenbuterol-induced hypertrophy of cardiac and skeletal muscle of rats
Palmer, R.M., Delday, M.I., McMillan, D.N., Noble, B.S., Bain, P. and Maltin, C.A. 1990. Effects of the cyclo-oxygenase inhibitor, fenbufen, on clenbuterol-induced hypertrophy of cardiac and skeletal muscle of rats. British Journal of Pharmacology. 101 (4), pp. 835-838. https://doi.org/10.1111/j.1476-5381.1990.tb14166.x