Life Sciences

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Sprint interval training (SIT) reduces serum epidermal growth factor (EGF), but not other inflammatory cytokines in trained older men.

Article

Yasar, Z., Elliott, B., Kyriakidou, Y., Nwokoma, C., Postlethwaite, R., Gaffney, C., Dewhurst, S. and Hayes, L. 2021. Sprint interval training (SIT) reduces serum epidermal growth factor (EGF), but not other inflammatory cytokines in trained older men. European Journal of Applied Physiology. Advanced online publication. https://doi.org/10.1007/s00421-021-04635-2

The effects of gradual vs. rapid weight loss on serum concentrations of myokines and body composition in overweight and obese females

Article

Bagheri, Reza, Ashtary-Larky, Damoon, Elliott, B., Willoughby, Darryn S., Kargarfard, Mehdi, Alipour, Meysam, Lamuchi-Deli, Nasrin, Kooti, Wesam, Asbaghi, Omid and Wong, Alexei 2021. The effects of gradual vs. rapid weight loss on serum concentrations of myokines and body composition in overweight and obese females. Archives of Physiology and Biochemistry. Advanced online publication. https://doi.org/10.1080/13813455.2021.1874020

Antibacterial Composite Materials Based on the Combination of Polyhydroxyalkanoates With Selenium and Strontium Co-substituted Hydroxyapatite for Bone Regeneration

Journal article

Marcello, Elena, Maqbool, Muhammad, Nigmatullin, Rinat, Cresswell, Mark, Jackson, Philip R., Basnett, Pooja, Knowles, Jonathan C., Boccaccini, Aldo R. and Roy, I. 2021. Antibacterial Composite Materials Based on the Combination of Polyhydroxyalkanoates With Selenium and Strontium Co-substituted Hydroxyapatite for Bone Regeneration. Frontiers in Bioengineering and Biotechnology. 9 647007. https://doi.org/10.3389/fbioe.2021.647007

Exploiting formyl peptide receptor 2 to promote microglial resolution: a new approach to Alzheimer's disease treatment.

Journal article

Wickstead, Edward S., Irving, Murray A., Getting, Stephen J. and McArthur, S. 2021. Exploiting formyl peptide receptor 2 to promote microglial resolution: a new approach to Alzheimer's disease treatment. The FEBS Journal. Advanced online publication. https://doi.org/10.1111/febs.15861

Characterisation of Phage Susceptibility Variation in Salmonellaenterica Serovar Typhimurium DT104 and DT104b

Journal article

Mohammed, M. and Orzechowska, B. 2021. Characterisation of Phage Susceptibility Variation in Salmonellaenterica Serovar Typhimurium DT104 and DT104b. MDPI Microorganisms. 9 (4). https://doi.org/10.3390/microorganisms9040865

Medicinal plants from the Himalayan region as potential novel antimicrobial and anti-inflammatory skin treatments.

Journal article

Heinrich, M., Jiang, H., Scotti, F., Booker, A., Walt, H., Weckerle, C. and Maake, C. 2021. Medicinal plants from the Himalayan region as potential novel antimicrobial and anti-inflammatory skin treatments. Journal of Pharmacy and Pharmacology. Advanced online publication. https://doi.org/10.1093/jpp/rgab039

Prostate Cancer Cell Extracellular Vesicles Increase Mineralisation of Bone Osteoblast Precursor Cells in an In Vitro Model

Journal article

Lanning, Ben, Webber, J., Uysal Onganer, P., Jiang, W., Clayton, Aled and Dart, D. 2021. Prostate Cancer Cell Extracellular Vesicles Increase Mineralisation of Bone Osteoblast Precursor Cells in an In Vitro Model. Biology. 10 (4), p. e318. https://doi.org/10.3390/biology10040318

Non-coding RNAs in pancreatic ductal adenocarcinoma: New approaches for better diagnosis and therapy

Journal article

Mortoglou, M., Tabin, Z.K., Arisan, E.D., Kocher, H.M. and Uysal Onganer, P. 2021. Non-coding RNAs in pancreatic ductal adenocarcinoma: New approaches for better diagnosis and therapy. Translational Oncology. 14 (7) 101090. https://doi.org/10.1016/j.tranon.2021.101090

Acute Alcohol Tissue Damage: Protective Properties of Betaine

Journal article

Petagine, L., Everitt, H.E., Preedy, V.R., Sherwood, R. and Patel, V.B. 2021. Acute Alcohol Tissue Damage: Protective Properties of Betaine. Journal of Renal and Hepatic Disorders. 5 (1), pp. 19-29. https://doi.org/10.15586/jrenhep.v5i1.96

Mitochondrial Function as a Potential Tool for Assessing Function, Quality and Adulteration in Medicinal Herbal Teas

Journal article

Booker, A., Woodley, S., Bell, J.D., Mould, R., Sahuri Arisoylu, M. and Kalampouka, I. 2021. Mitochondrial Function as a Potential Tool for Assessing Function, Quality and Adulteration in Medicinal Herbal Teas. Frontiers in Pharmacology. 660938. Advanced online publication. https://doi.org/10.3389/fphar.2021.660938

Dr Manal Mohammed for The Conversation about the long-term problems of hand sanitiser

Other

Mohammed, M. 2021. Dr Manal Mohammed for The Conversation about the long-term problems of hand sanitiser. The Conversation.

Acetate induces growth arrest in colon cancer cells through modulation of mitochondrial function

Journal article

Sahuri Arisoylu, M., Mould, R., Shinjyo, N., Bligh, S.W.A., Nunn, A., Guy, G., Thomas, E.L. and Bell, J.D. 2021. Acetate induces growth arrest in colon cancer cells through modulation of mitochondrial function. Frontiers in Nutrition: Nutrition and Metabolism. 8 588466. https://doi.org/10.3389/fnut.2021.588466

The Neuroscience of Depression: Genetics, Cell Biology, Neurology, Behaviour, and Diet

Book

Martin, C.R., Hunter, L.A., Patel, V., Preedy, V.R. and Rajendram, R. (ed.) 2021. The Neuroscience of Depression: Genetics, Cell Biology, Neurology, Behaviour, and Diet. Academic Press.

Recommended resources on the neuroscience of depression: Genetics, cell biology, neurology, behavior, and diet

Book chapter

Rajendram, R., Patel, V. and Preedy, V.R. 2021. Recommended resources on the neuroscience of depression: Genetics, cell biology, neurology, behavior, and diet. in: Martin, C.R., Hunter, L.A., Patel, V., Preedy, V.R. and Rajendram, R. (ed.) The Neuroscience of Depression: Genetics, Cell Biology, Neurology, Behaviour, and Diet Academic Press. pp. 531-537

Characterization of a biosurfactant producing electroactive Bacillus sp. for enhanced Microbial Fuel Cell dye decolourisation

Journal article

Gomaa, Ola M., Selim, Nabila, Fathy, Reham, Maghrawy, Heba Hamed, Gamal, Marwa, El Kareem, Hussein Abd, Kyazze, Godfrey and Keshavarz, Tajalli 2021. Characterization of a biosurfactant producing electroactive Bacillus sp. for enhanced Microbial Fuel Cell dye decolourisation. Enzyme and Microbial Technology. 147 109767. https://doi.org/10.1016/j.enzmictec.2021.109767

Bioelectrochemical remediation of petroleum hydrocarbons

Conference poster

Yayork, B., Anyogu, A. and Kyazze, G. 2021. Bioelectrochemical remediation of petroleum hydrocarbons. Society for Applied Microbiology Early Career Scientists conference. Online via Zoom 22 - 26 Mar 2021

Strategic Ingestion of High-Protein Dairy Milk during a Resistance Training Program Increases Lean Mass, Strength, and Power in Trained Young Males

Journal article

Pourabbas, M., Bagheri, Reza, Hooshmand Moghadam, B., S. Willoughby, Darryn, G. Candow, Darren, Elliott, B., C. Forbes, S., Ashtary-Larky, Damoon, Eskandari, Mozhgan, Wong, Alexei and Dutheil, Frédéric 2021. Strategic Ingestion of High-Protein Dairy Milk during a Resistance Training Program Increases Lean Mass, Strength, and Power in Trained Young Males. Nutrients. 13 (3), p. e948. https://doi.org/10.3390/nu13030948

A benzimidazole-based new fluorogenic differential/sequential chemosensor for Cu2+, Zn2+, CN-, P2O7 4-, DNA, its live-cell imaging and pyrosequencing applications

Journal article

Anbu, S., Paul, Anup, Surendranath, K., Solaiman, N. and Pombeiro, Armando J.L. 2021. A benzimidazole-based new fluorogenic differential/sequential chemosensor for Cu2+, Zn2+, CN-, P2O7 4-, DNA, its live-cell imaging and pyrosequencing applications. Sensors and Actuators B: Chemical. 337 129785. https://doi.org/10.1016/j.snb.2021.129785

Post-Translational Protein Deimination Signatures in Plasma and Plasma EVs of Reindeer ( Rangifer tarandus )

Journal article

D'alessio, S., Thorgeirsdóttir, Stefanía, Kraev, Igor, Skírnisson, Karl and Lange, S. 2021. Post-Translational Protein Deimination Signatures in Plasma and Plasma EVs of Reindeer ( Rangifer tarandus ). Biology. 10 (3) e222. https://doi.org/10.3390/biology10030222

Identification and characterisation of the lactic acid bacteria associated with the traditional fermentation of a dairy fermented product

Journal article

Obioha, P., Ouoba, L.I.I., Anyogu, A., Awamaria, B., Atchia, S, Ojimelukwe, P.C, Sutherland, J.P and Ghoddusi, H. 2021. Identification and characterisation of the lactic acid bacteria associated with the traditional fermentation of a dairy fermented product. Brazilian Journal of Microbiology. Advanced online publication. https://doi.org/10.1007/s42770-021-00461-y

Chemical Authentication of Botanical Ingredients: A Review of Commercial Herbal Products

Journal article

Ichim, M.C. and Booker, A. 2021. Chemical Authentication of Botanical Ingredients: A Review of Commercial Herbal Products. Frontiers in Pharmacology. 666850. Advanced online publication. https://doi.org/10.3389/fphar.2021.666850

Stop Superbugs!

Other

Mohammed, M. 2021. Stop Superbugs!

Peptidylarginine Deiminase (PAD) and Post-Translational Protein Deimination—Novel Insights into Alveolata Metabolism, Epigenetic Regulation and Host–Pathogen Interactions

Journal article

Kristmundsson, Árni, Erlingsdóttir, Ásthildur and Lange, S. 2021. Peptidylarginine Deiminase (PAD) and Post-Translational Protein Deimination—Novel Insights into Alveolata Metabolism, Epigenetic Regulation and Host–Pathogen Interactions. Biology. 10 (3) e177. https://doi.org/10.3390/biology10030177

MicroRNAs for Virus Pathogenicity and Host Responses, Identified in SARS-CoV-2 Genomes, May Play Roles in Viral-Host Co-Evolution in Putative Zoonotic Host Species.

Journal article

Lange, S., Arisan, E., Grant, Guy H and Uysal Onganer, P. 2021. MicroRNAs for Virus Pathogenicity and Host Responses, Identified in SARS-CoV-2 Genomes, May Play Roles in Viral-Host Co-Evolution in Putative Zoonotic Host Species. Viruses. 13 (1) 117. https://doi.org/10.3390/v13010117

MiR-21 is Required for the Epithelial–Mesenchymal Transition in MDA-MB-231 Breast Cancer Cells

Journal article

Arisan, E., Rencuzogullari, O., Cieza-Borrella, Clara, Miralles Arenas, Francesc Miralles, Dwek, M., Lange, S. and Uysal Onganer, P. 2021. MiR-21 is Required for the Epithelial–Mesenchymal Transition in MDA-MB-231 Breast Cancer Cells. International Journal of Molecular Sciences. 22 (4), p. e1557 1557. https://doi.org/10.3390/ijms22041557

Editorial: Tissue Remodeling in Health and Disease Caused by Bacteria, Parasites, Fungi, and Viruses

Edited issue

Lange, S. and Ramirez, M.I. 2021. Editorial: Tissue Remodeling in Health and Disease Caused by Bacteria, Parasites, Fungi, and Viruses. Frontiers in Cellular and Infection Microbiology. 11 642311. https://doi.org/10.3389/fcimb.2021.642311

Peptidylarginine Deiminase Inhibitor Application, Using Cl-Amidine, PAD2, PAD3 and PAD4 Isozyme-Specific Inhibitors in Pancreatic Cancer Cells, Reveals Roles for PAD2 and PAD3 in Cancer Invasion and Modulation of Extracellular Vesicle Signatures

Journal article

Uysal Onganer, P., D'alessio, S., Mortoglou, M., Kraev, I. and Lange, S. 2021. Peptidylarginine Deiminase Inhibitor Application, Using Cl-Amidine, PAD2, PAD3 and PAD4 Isozyme-Specific Inhibitors in Pancreatic Cancer Cells, Reveals Roles for PAD2 and PAD3 in Cancer Invasion and Modulation of Extracellular Vesicle Signatures. International Journal of Molecular Sciences. 22 (3) 1396. https://doi.org/10.3390/ijms22031396

Formulation and Characterization of Phytostanol Ester Solid Lipid Nanoparticles for the Management of Hypercholesterolemia: An ex vivo Study.

Journal article

Shrestha, S., Ghebremeskel, K., White, K., Minelli, C., Tewfik, I., Thapa, Panna and Tewfik, S. 2021. Formulation and Characterization of Phytostanol Ester Solid Lipid Nanoparticles for the Management of Hypercholesterolemia: An ex vivo Study. International Journal of Nanomedicine. 16, pp. 1977-1992. https://doi.org/10.2147/IJN.S276301

Cohesin mutations alter DNA damage repair and chromatin structure and create therapeutic vulnerabilities in MDS/AML

Journal article

Tothova, Z., Valton, A., Gorelov, R., Vallurupalli, M., Krill-Burger, J.M., Holmes, A., Landers, C.C., Haydu, J.E., Malolepsza, E., Hartigan, C.R., Donahue, M., Popova, K.D., Koochaki, S.H.J., Venev, S.V., Rivera, J.F., Chen, E., Lage, K., Schenone, M., D'Andrea, A.D., Carr, S.A., Morgan, E.A., Dekker, J. and Ebert, B.L. 2021. Cohesin mutations alter DNA damage repair and chromatin structure and create therapeutic vulnerabilities in MDS/AML. JCI Insight. 6 (3) e142149. https://doi.org/10.1172/jci.insight.142149

MicroRNAs for Virus Pathogenicity and Host Responses, Identified in SARS-CoV-2 Genomes, May Play Roles in Viral-Host Co-Evolution in Putative Zoonotic Host Species

Journal article

Lange, S., Arisan, E.D., Grant, G.H. and Uysal Onganer, P. 2021. MicroRNAs for Virus Pathogenicity and Host Responses, Identified in SARS-CoV-2 Genomes, May Play Roles in Viral-Host Co-Evolution in Putative Zoonotic Host Species. MDPI Viruses. 13 (1), p. 117 10.3390/v13010117 . https://doi.org/10.3390/v13010117

The Proteome and Citrullinome of Hippoglossus hippoglossus Extracellular Vesicles—Novel Insights into Roles of the Serum Secretome in Immune, Gene Regulatory and Metabolic Pathways

Journal article

Magnadóttir, B., Kraev, I., Dodds, A.W. and Lange, S. 2021. The Proteome and Citrullinome of Hippoglossus hippoglossus Extracellular Vesicles—Novel Insights into Roles of the Serum Secretome in Immune, Gene Regulatory and Metabolic Pathways. International Journal of Molecular Sciences. 22 (2) 875. https://doi.org/10.3390/ijms22020875

Laccase Immobilization Strategies for Application as a Cathode Catalyst in Microbial Fuel Cells for Azo Dye Decolourization

Journal article

Mani, Priyadharshini, Fidal, V. T., Keshavarz, Taj, Chandra, T. S. and Kyazze, G. 2021. Laccase Immobilization Strategies for Application as a Cathode Catalyst in Microbial Fuel Cells for Azo Dye Decolourization. Frontiers in Microbiology. 11 620075. https://doi.org/10.3389/fmicb.2020.620075

Processes Underlying Glycemic Deterioration in Type 2 Diabetes: An IMI DIRECT Study.

Journal article

Bizzotto, R., Jennison, Christopher, Jones, A., Kurbasic, Azra, Tura, Andrea, Kennedy, Gwen, Bell, Jimmy D, Thomas, E Louise, Frost, G., Eriksen, Rebeca, Koivula, R., Brage, Soren, Kaye, Jane, Hattersley, A., Heggie, Alison, McEvoy, Donna, 't Hart, Leen M, Beulens, J., Elders, Petra, Musholt, Petra B, Ridderstråle, M., Hansen, Tue H, Allin, K., Hansen, T., Vestergaard, Henrik, Lundgaard, Agnete T, Thomsen, Henrik S, De Masi, Federico, Tsirigos, Konstantinos D, Brunak, Søren, Viñuela, Ana, Mahajan, A., McDonald, T., Kokkola, Tarja, Forgie, Ian M, Giordano, Giuseppe N, Pavo, Imre, Ruetten, Hartmut, Dermitzakis, Emmanouil, McCarthy, Mark I, Pedersen, Oluf, Schwenk, Jochen M, Adamski, Jerzy, Franks, P., Walker, Mark, Pearson, E., Mari, A. and IMI DIRECT consortium 2021. Processes Underlying Glycemic Deterioration in Type 2 Diabetes: An IMI DIRECT Study. Diabetes Care. 44 (2), pp. 511-518. https://doi.org/10.2337/dc20-1567

Glial regenerative cell types in the superficial cortex in cortical dysplasia subtypes

Journal article

Liu, J., Reeves, C., van der Pijl, R. and Thom, M. 2021. Glial regenerative cell types in the superficial cortex in cortical dysplasia subtypes. Epilepsy Research. 169 106529. https://doi.org/10.1016/j.eplepsyres.2020.106529

Integrating molecular modelling methods to advance influenza A virus drug discovery

Journal article

Patel, H. and Kukol, A. 2021. Integrating molecular modelling methods to advance influenza A virus drug discovery. Drug Discovery Today. 26 (2), pp. 503-510. https://doi.org/10.1016/j.drudis.2020.11.014

The chimera of choice in UK food policy 1976-2018

Journal article

Burges Watson, D.L., Draper, A. and Willis, W.J. 2021. The chimera of choice in UK food policy 1976-2018. British Food Journal. 123 (4), pp. 1596-1609. https://doi.org/10.1108/BFJ-10-2020-0982

Peptidylarginine deiminases and extracellular vesicles: prospective drug targets and biomarkers in central nervous system diseases and repair.

Article

Lange, Sigrun 2021. Peptidylarginine deiminases and extracellular vesicles: prospective drug targets and biomarkers in central nervous system diseases and repair. Neural Regeneration Research. 16 (5), pp. 934-938. https://doi.org/NeuralRegenRes_2021_16_5_934_297058

Processes Underlying Glycemic Deterioration in Type 2 Diabetes: An IMI DIRECT Study

Journal article

Bizzotto, R., Jennison, C., Jones, A., Kurbasic, A., Kennedy, G., Bell, J.D., Thomas, E.L., Frost, G., Eriksen, R., Koivula, R., Brage, S., Kaye, J., Hattersley, A., Heggie, A., McEvoy, D., Hart, L.M., Beulens, J.W., Elders, P., Musholt, P.B., Ridderstråle, M., Hansen, T., Allin, K., Hansen, T., Vestergaard, H., Lundgaard, A.T., Thomsen, H.S., Masi, F., Tsirigos, K.D., Brunak, S., Viñuela, A., Mahajan, A., McDonald, T.J., Kokkola, T., Forgie, I., Giordano, G.N., Pavo, I., Ruetten, H., Dermitzakis, E., McCarthy, M., Pedersen, O., Schwenk, J., Adamski, J., Franks, P., Walker, M., Pearson, E. and Mari, A. 2021. Processes Underlying Glycemic Deterioration in Type 2 Diabetes: An IMI DIRECT Study. Diabetes Care. 44 (2), pp. 511-518. https://doi.org/10.2337/dc20-1567

The effect of astaxanthin supplementation on performance and fat oxidation during a 40 km cycling time trial

Journal article

Brown, D.R., Warner, A.R., Deb, S., Gough, L.A., Sparks, S.A. and McNaughton, L.R. 2021. The effect of astaxanthin supplementation on performance and fat oxidation during a 40 km cycling time trial. Journal of Science and Medicine in Sport. 24 (1), pp. 92-97. https://doi.org/10.1016/j.jsams.2020.06.017

Nutritional Management in Polycystic Ovary Syndrome: Challenges and opportunities

Journal article

Hmedeh, C., Ghazeeri, G. and Tewfik, I. 2021. Nutritional Management in Polycystic Ovary Syndrome: Challenges and opportunities. International Journal of Food Safety, Nutrition and Public Health. 6 (2), pp. 120-130. https://doi.org/10.1504/IJFSNPH.2021.113389


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