Life Sciences

Zupancic, S., Kocbek, P., Kristl, J., Zariwala, M., Renshaw, D., Gul, M.O., Elsaid, Z., Taylor, K.M.G. and Somavarapu, S. 2014. Formulation and characterization of curcumin loaded DQAsomes for pulmonary delivery. 10th International Conference and Workshop on Biological Barriers. Saarbrücken 16 - 21 Feb 2014

Zariwala, M., Kosicka, A., MacKenzie, R. and Renshaw, D. 2014. Serum ferritin levels are correlated with total adiposity, but not BMI in obese males. Society for Endocrinology BES 2014. Liverpool, UK 24 - 27 Mar 2014 BioScientifica Ltd.. https://doi.org/10.1530/endoabs.34.P255

Zariwala, M. and Farnaud, S. 2014. A human cell model of Parkinson’s disease confirms iron accumulation in dopaminergic neurons following 6-OHDOPA treatment. European Iron Club Annual Meeting 2014. Verona, Italy 11 - 14 Sep 2014

Zariwala, M., Bendre, H., Markiv, A., Farnaud, S., Somavarapu, S. and Renshaw, D. 2014. Fabrication and characterization of novel hydrophobically modified chitosan nanoliposomes for oral iron delivery. European Iron Club Annual Meeting 2014. Verona, Italy 11 - 14 Sep 2014

Zupančič, Š., Kocbek, P., Zariwala, M., Renshaw, D., Gul, M.O., Elsaid, Z., Taylor, K.M.G. and Somavarapu, S. 2014. Design and Development of Novel Mitochondrial Targeted Nanocarriers, DQAsomes for Curcumin Inhalation. Molecular Pharmaceutics. 11 (7), pp. 2334-2345. https://doi.org/10.1021/mp500003q

Butterworth, S., Overduin, M. and Barr, A.J. 2014. Targeting protein tyrosine phosphatase SHP2 for therapeutic intervention. Future Medicinal Chemistry. 6 (12), pp. 1423-1437. https://doi.org/10.4155/fmc.14.88

Fagan-Watson, B., Watson, T., Elliott, B., Vanner, R., Shaw, Ben and Morris, S. 2014. What range of methods is available to evaluate the implementation and impact of complex environmental policies on complex systems? A report to the Department for Environment, Food and Rural Affairs. Policy Studies Institute. Defra, London.

Derges, J., Clow, A., Lynch, R., Jain, S., Phillips, G., Petticrew, M., Renton, A. and Draper, A. 2014. ‘Well London’ and the benefits of participation: results of a qualitative study nested in a cluster randomised trial. BMJ Open. 2014 (4), p. e003596 e003596. https://doi.org/10.1136/bmjopen-2013-003596

Walker, K. and Green, J. 2014. The development of Eucalyptus as a medicine. National Institute of Medical Herbalists 150th Annual Conference. Nottingham 09 - 13 Oct 2014

Pérez Blanco, E. and Lewis, J. 2014. A comparative study of Alexandrium tamarense cyst distribution in Belfast Lough. European Journal of Phycology. 49 (2), pp. 255-263. https://doi.org/10.1080/09670262.2014.912761

Taylor, J., Kegel, J.U., Lewis, J. and Medlin, L.K. 2014. Validation of the detection of Alexandrium spp using specific RNA probes tested in a microarray format: Calibration of signal using variability of RNA content with environmental conditions. Harmful Algae. 37, pp. 17-27. https://doi.org/10.1016/j.hal.2014.05.001

Voyias, P., Antonysunil, A., Kumasaiyai, W., Kyrou, I., Vrbikova, J., Hainer, V., Fried, M., Sramkova, P., Saravanan, P., Kumar, S., McTernan, P. and Tripathi, G. 2014. Unfolded protein response in adipose tissue of obese diabetic women significantly improved 6 months post bariatric surgery, irrespective of malabsorptive or bypass operation type and correlates with plasma glucose concentration. Society for Endocrinology BES 2014. Liverpool 24 - 27 May 2017 Society for Endocrinology. https://doi.org/10.1530/endoabs.34.P269

Al-Disi, D., Al-Daghri, N., Khan, N., Alsaif, M., Alfadda, A., Sabico, S., Tripathi, G. and McTernan, P. 2014. A 3-month low fat diet leads to significant lipid profile improvement in obese T2DM Saudi subjects, without substantial weight loss, and the capacity to manage a damaging high-fat meal challenge more appropriately post intervention. Society for Endocrinology BES 2014. Liverpool 24 - 27 May 2014 Society for Endocrinology. https://doi.org/10.1530/endoabs.34.P223

Kumsaiyai, W., Al-Daghri, N., Kyrou, I., Vrbikova, J., Hainer, V., Fried, M., Sramkova, P., Barber, T., S Kumar,, Tripathi, G. and McTernan, P. 2014. Systemic triglycerides as a key determinant of TLR regulated inflammatory risk in human adipose tissue post bariatric surgical intervention and weight loss. Society for Endocrinology BES 2014. Liverpool 24 - 27 Mar 2014 Society for Endocrinology. https://doi.org/10.1530/endoabs.34.P238

Piya, M., Reddy, N., Campbell, A., Hattersley, J., Halder, L., Tripathi, G., Tahrani, A., Kumar, S., Barber, T. and McTernan, P. 2014. Meal size and frequency influences metabolic endotoxaemia and inflammatory risk but has no effect on diet induced thermogenesis in either lean or obese subjects. Society for Endocrinology BES 2014. Liverpool 24 - 27 May 2014 Society for Endocrinology. https://doi.org/10.1530/endoabs.34.P226

Antonysunil, A., Vatish, M., Lawson, A., Wood, C., Sivakumar, K., Webster, C., Anderson, N., McTernan, P., Tripathi, G. and Saravanan, P. 2014. Elevated cord leptin from low B12 mothers predicts birth weight. Society for Endocrinology BES 2014. Liverpool 24 - 27 May 2014 Society for Endocrinology. https://doi.org/10.1530/endoabs.34.P262

Al-Daghri, N., Al-Attas, O., Alokail, M., Alkharfy, K., Yousef, M., Vinodson, B., Amer, O., Alnaami, A., Sabico,S., Tripathi, G., Piya, M., McTernan, P. and Chrousos, G. 2014. Maternal inheritance of circulating irisin in humans (954.1). FASEB Journal. 28 (1 Supplement), p. 954.1. https://doi.org/10.1042/CS20130426

Voyias, P., Antonysunil, A., Kumasaiyai, W., Kyrou, I., Vrbikova, J., Hainer, V., Fried, M., Sramkova, P., Saravanan, P., Kumar, S., McTernan, P. and Tripathi, G. 2014. Bariatric surgery induced weight loss and systemic glucose regulates intracellular unfolded protein response within human adipose tissue from type 2 diabetes mellitus patients. 74th Scientific Sessions of the American Diabetes Association. San Francisco, USA 13 - 17 Jun 2014

Adaikalakoteswari, A., Finer, S., Voyias, P.D., McCarthy, M., Vatish, M., Moore, J., Smart-Halajko, M., Bawazeer, N., Al-Daghri, N.M., McTernan, P.G., Hitman, G.A., Saravanan, P. and Tripathi, G. 2014. Methyl Donor Deficiency Due to Low Vitamin B12 Impairs Insulin Signalling in Human Adipocytes by Down Regulating Akt Pathway via PTEN and TRB3. 74th Scientific Sessions of the American Diabetes Association. San Francisco, USA 13 - 17 Jun 2014

Patel, A., N Williams, N., Nwokolo, C., Tripathi, G. and Arasaradnam, R. 2014. PWE-001 Field Cancerisation Theory In Colorectal Cancer (crc): What Role Do Fibroblast Growth Factors Have? British Society of Gastroenterology Annual General Meeting. 16 - 19 Jun 2014 BMJ. https://doi.org/10.1136/gutjnl-2014-307263.261

Adaikalakoteswari, A., Finer, S., Hitman, G.A., Saravanan, P. and Tripathi, G. 2014. Vitamin B12 deficiency induces adipocyte dysfunction via enhanced cholesterol biosynthesis, unfolded protein response and associated epigenetic marks. 41st UK Adipose Tissue Discussion Group. Norwich 15 Dec 2014

Reddy, N.L., Jones, T.A., Wayte, S.C., Adesanya, O., Sankar, S., Yeo, Y.C., Tripathi, G., McTernan, P.G., Randeva, H.S., Kumar, S., Hutchinson, C.E. and Barber, T.M. 2014. Identification of Brown Adipose Tissue Using MR Imaging in a Human Adult With Histological and Immunohistochemical Confirmation. The Journal of Clinical Endocrinology & Metabolism. 99 (1), pp. E117-E121. https://doi.org/10.1210/jc.2013-2036

Al-Daghri, N.M., Al-Attas, O.S., Alokail, M.S., Alkharfy, K.M., Yousef, M., Vinodson, B., Amer, O.E., Alnaami, A.M., Sabico, S., Tripathi, G., Piya, M.K., McTernan, P.G. and Chrousos, G.P. 2014. Maternal inheritance of circulating irisin in humans. Clinical Science. 126 (12), pp. 837-844. https://doi.org/10.1042/CS20130426

Adaikalakoteswari, A., Jayashri, R., Sukumar, N., Venkataraman, H., Pradeepa, R., Gokulakrishnan, K., Anjana, R., McTernan, P.G., Tripathi, G., Patel, V., Kumar, S,, Mohan, V. and Saravanan, P. 2014. Vitamin B12 deficiency is associated with adverse lipid profile in Europeans and Indians with type 2 diabetes. Cardiovascular Diabetology. 13 (1), p. 129. https://doi.org/10.1186/s12933-014-0129-4

Piya, M.K., Harte, A.L., Sivakumar, K., Tripathi, G., Voyias, P.D., James, S., Sabico, S., Al-Daghri, N.M., Saravanan, P., Barber, T.M., Kumar, S., Vatish, M. and McTernan, P.G. 2014. The Identification of Irisin in Human Cerebrospinal Fluid: Influence of Adiposity, Metabolic Markers and Gestational Diabetes. American Journal of Physiology - Endocrinology and Metabolism. 306 (5), pp. E512-E518. https://doi.org/10.1152/ajpendo.00308.2013

Zariwala, M., Farnaud, S., Merchant, Z., Somavarapu, S. and Renshaw, D. 2014. Ascorbyl palmitate/DSPE-PEG nanocarriers for oral iron delivery:Preparation, characterisation and in vitro evaluation. Colloids and Surfaces B: Biointerfaces. 115 (1), p. 86– 92. https://doi.org/10.1016/j.colsurfb.2013.11.028

Zupančič, Š., Kocbek, P., Zariwala, M., Renshaw, D., Gul, M.O., Elsaid, Z., Taylor, K.M.G. and Somavarapu, S. 2014. Design and Development of Novel Mitochondrial Targeted. Molecular Pharmaceutics. 11 (7), pp. 2334-2345. https://doi.org/10.1021/mp500003q

Anyogu, A., Awamaria, B., Sutherland, J.P. and Ouoba, L.I.I. 2014. Molecular characterisation and antimicrobial activity of bacteria associated with submerged lactic acid cassava fermentation. Food Control. 39, pp. 119-127. https://doi.org/10.1016/j.foodcont.2013.11.005

Gerbault, P., Allaby, R.G., Boivin, N., Rudzinski, A., Grimaldi, I.M., Pires, J.C., Climer Vigueira, C., Dobney, K., Gremillion, K.J., Barton, L., Arroyo-Kalin, M., Purugganan, M.D., Rubio de Casas, R., Bollongino, R., Burger, J., Fuller, D.Q., Bradley, D.G., Balding, D.J., Richerson, P.J., Gilbert, M.T., Larson, G. and Thomas, M.G. 2014. Storytelling and story testing in domestication. Proceedings of the National Academy of Sciences of the United States of America. 111 (17), pp. 6159-6164. https://doi.org/10.1073/pnas.1400425111

Gerbault, P., Liebert, A., Swallow, D.M. and Thomas, M.G. 2014. Lactose malabsorption and nutrition. in: Lomer, M. (ed.) Advanced Nutrition and Dietetics in Gastroenterology Wiley. pp. 202-209

Granger, C.A., Pilkington, K., Draper, A. and Polley, M.J. 2014. Working with people affected by cancer – Phase 1 of a mixed methods exploration of practitioner perspectives in nutritional therapy. European Journal of Integrative Medicine. 6 (5), pp. 613-614. https://doi.org/10.1016/j.eujim.2014.07.010

Locke, I.C. and Murray, J.F. 2014. Anatomy, embryology, and cell families. in: Orchard, G. and Nation, B. (ed.) Cell Structure & Function Oxford, UK Oxford University Press. pp. 82-110

Can, V.C., Locke, I.C. and Getting, S.J. 2014. The melanocortin receptor antagonist SHU9119 inhibits the anti-inflammatory/pro-resolving properties of a-MSH and D[TRP8]-y-MSH in lipopolysaccharide stimulated chondrocytes. Pharmacology 2014. Queen Elizabeth Centre II, London, UK 16 Dec 2014 British Pharmacological Society.

de Ferrars, R.M., Czank, C., Saha, S., Needs, P.W., Zhang, Q., Raheem, S., Botting, N.P., Kroon, P.A. and Kay, C.D. 2014. Methods for Isolating, Identifying, and Quantifying Anthocyanin Metabolites in Clinical Samples. Analytical Chemistry. 86 (20), pp. 10052-10058. https://doi.org/10.1021/ac500565a

Moykkynen, T., Coleman, S.K., Semenov, A. and Keinänen, K. 2014. The N-terminal domain modulates α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor desensitization. Journal of Biological Chemistry. 289 (19), pp. 13197-13205. https://doi.org/10.1074/jbc.M113.526301

Luchkina, N.V., Huupponen, J., Clarke, V.R., Coleman, S.K., Keinänen, K., Taira, T. and Lauri SE 2014. Developmental switch in the kinase dependency of long-term potentiation depends on expression of GluA4 subunit-containing AMPA receptors. Proceedings of the National Academy of Sciences of the United States of America. 111 (11), p. 4321–4326. https://doi.org/10.1073/pnas.1315769111

Lange, S., Stratton, D., Kholia, S., Jorfi, S., Antwi-Baffour, S. and Inal, J. 2014. Label-free real-time acoustic sensing of microvesicle release from prostate cancer (PC3) cells using a Quartz Crystal Microbalance. Biochemical and Biophysical Research Communications. 453 (3), p. 619–624. https://doi.org/10.1016/j.bbrc.2014.09.132

Lange, S., Rocha-Ferreira, E., Thei, L., Mawjee, P., Thompson, P.R., Nicholas, A.P., Hristova, M., Peebles, D. and Raivich, G. 2014. Peptidylarginine deiminases (PADs): novel drug targets for prevention of neuronal damage following hypoxic ischemic insult (HI) in neonates. Journal of Neurochemistry. 130 (4), pp. 555-562. https://doi.org/10.1111/jnc.12744

Rocha-Ferreira, E., Francesch-Domenech, E., Thei, L., Rahim, A., Lange, S., Peebles, D., Hristova, M. and Raivich, G. 2014. The Role of Infection and the TNF Family of Cytokines in Neonatal Hypoxic-Ischemic Brain Injury. Reproductive Sciences. 21 (3 suppl), pp. 108A-109A. https://doi.org/10.1177/1933719114528275

Elliott, B., Renshaw, D., Getting, S.J., Watt, P.W. and MacKenzie, R. 2014. Acute hypoxia alters myotube size in vitro and myostatin signalling in vivo. FASEB. San Diego Jul 2015 Federation of American Societies for Experimental Biology.