Life Sciences

CollegeLiberal Arts and Sciences
HeadProf Alistair Mathie
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The role of acute hypoxia in skeletal muscle atrophy

Conference poster

Elliott, B., Renshaw, D., Getting, S.J., Watt, P., Howard, D. and MacKenzie, R. 2014. The role of acute hypoxia in skeletal muscle atrophy. Physiology. London 30 Jun 2014 The Physiological Society.

Functional Studies On Receptor-Type Protein Tyrosine Phosphatases Of The R3 Subgroup Using Bimolecular Fluorescence Complementation (BiFC) Assays

Conference poster

Dorofejeva, O., Dwek, M. and Barr, A.J. 2014. Functional Studies On Receptor-Type Protein Tyrosine Phosphatases Of The R3 Subgroup Using Bimolecular Fluorescence Complementation (BiFC) Assays . Pharmacology 2014. London 16 Dec 2014 British Pharmacological Society.

Antibody validation of immunohistochemistry for biomarker discovery: Recommendations of a consortium of academic and pharmaceutical based histopathology researchers

Article

Howat, W.J., Lewis, A., Jones, P., Kampf, C., Pontén, F., F, van der Loos, C.M., Gray, N., Womack, C. and Warford, A. 2014. Antibody validation of immunohistochemistry for biomarker discovery: Recommendations of a consortium of academic and pharmaceutical based histopathology researchers. Methods. 70 (1), pp. 34-38. https://doi.org/10.1016/j.ymeth.2014.01.018

Antigen retrieval, blocking, detection and visualisation systems in immunohistochemistry: A review and practical evaluation of tyramide and rolling circle amplification systems.

Article

Warford, A., Akbar, H. and Riberio, D. 2014. Antigen retrieval, blocking, detection and visualisation systems in immunohistochemistry: A review and practical evaluation of tyramide and rolling circle amplification systems. Methods. 70 (1), p. 28–33. https://doi.org/10.1016/j.ymeth.2014.03.001

Morphological and molecular characterization of a marine fish trypanosome from South Africa, including its development in a leech vector

Journal article

Hayes, P.M., Lawton, S.P., Smit, N.J., Gibson, W.C. and Davies, A.J. 2014. Morphological and molecular characterization of a marine fish trypanosome from South Africa, including its development in a leech vector. Parasites and Vectors. 7 (50). https://doi.org/10.1186/1756-3305-7-50

Modulation of a cytoskeletal calpain-like protein induces major transitions in trypanosome morphology

Article

Hayes, P.M., Varga, V., Olego-Fernandez, S., Sunter, J., Ginger, M.L., Gull, K. and Dr Michael Ginger 2014. Modulation of a cytoskeletal calpain-like protein induces major transitions in trypanosome morphology. Journal of Cell Biology. 206 (3), pp. 377-384. https://doi.org/10.1083/jcb.201312067

The changing landscape of e-textbooks: smarter, interactive and engaging learning

Conference paper

Kwan, I., Wright, T. and Rhodes, G. 2014. The changing landscape of e-textbooks: smarter, interactive and engaging learning. Westminster Learning and Teaching Symposium. Marylebone, London

Learning by devising Assessments: How to harness the enthusiasm of our students in their own learning.

Conference paper

Rhodes, G. 2014. Learning by devising Assessments: How to harness the enthusiasm of our students in their own learning. Crowdsourcing in HE. Bristol Feb 2014

The effect of playground and nature-based interventions on physical activity and self-esteem in UK school children

Article

Barton, J., Sandercock, G., Pretty, J. and Wood, C. 2014. The effect of playground and nature-based interventions on physical activity and self-esteem in UK school children. International Journal of Environmental Health Research. 25 (2), pp. 196-206. https://doi.org/10.1080/09603123.2014.915020

Interactions between physical activity and the environment to improve adolescent psychological wellbeing: a randomised controlled trial

Article

Wood, C., Sandercock, G. and Barton, J. 2014. Interactions between physical activity and the environment to improve adolescent psychological wellbeing: a randomised controlled trial. International Journal of Environment and Health. 7 (2), pp. 144-155. https://doi.org/10.1504/IJENVH.2014.067359

A repeated measures experiment of school playing environment to increase physical activity and enhance self esteem in UK school children

Article

Wood, C., Gladwell, V. and Barton, J. 2014. A repeated measures experiment of school playing environment to increase physical activity and enhance self esteem in UK school children. PLoS ONE. 9 (9) e108701. https://doi.org/10.1371/journal.pone.0108701

Poly(3-hydroxyoctanoate): a novel natural material for cardiac tissue engineering

Conference paper

Dubey, P., Bagdadi, A., Boccaccini, A., Knowles, J., Stevens, M., Harding, S., Roy, I. and Ravi, S. 2014. Poly(3-hydroxyoctanoate): a novel natural material for cardiac tissue engineering. BHF Regenerative Medicine Centre Joint Annual and SAB meetings. Imperial College, London 31 Jul 2014

Nerve tissue engineering using blends of polyhydroxyalkanoates

Conference poster

Lizarraga Valderrama, L., Percy, L. and Roy, I. 2014. Nerve tissue engineering using blends of polyhydroxyalkanoates. 8th International Conference on Polymer and Fiber Biotechnology. Braga, Portugal 25 May 2014

Production of polyhydroxyalkanoates and their medical applications

Conference paper

Roy, I. 2014. Production of polyhydroxyalkanoates and their medical applications. International Symposium on Biopolymers. Santos, Brazil 30 Sep 2014

Polyhydroxyalkanoate (PHA) based blends, composites and nanocomposites

Book

Roy, I. and Visakh, P.M. (ed.) 2014. Polyhydroxyalkanoate (PHA) based blends, composites and nanocomposites. London Royal Society of Chemistry.

Agro-Industrial Waste Materials as Substrates for the Production of Poly(3-Hydroxybutyric Acid)

Article

Sukan, A., Roy, I. and Keshavarz, T. 2014. Agro-Industrial Waste Materials as Substrates for the Production of Poly(3-Hydroxybutyric Acid). Journal of Biomaterials and Nanobiotechnology. 5 (4), pp. 229-240. https://doi.org/10.4236/jbnb.2014.54027

Synthesis and characterisation of novel keratin-cellulose based graft composites

Conference poster

Iqbal, H.M.N., Kyazze, G., Keshavarz, T. and Tron, T. 2014. Synthesis and characterisation of novel keratin-cellulose based graft composites. University of Westminster Faculty of Science and Technology Postgraduate Fair. University of Westminster, London, UK 29 Apr 2014

Enzymatic grafting: A novel approach to develop multifunctional materials of interest

Conference poster

Iqbal, H.M.N., Kyazze, G., Keshavarz, T. and Tron, T. 2014. Enzymatic grafting: A novel approach to develop multifunctional materials of interest. 8th International Conference on Energy, Materials and Nanotechnology. Florida, USA 25 Nov 2014

Melanocortin peptides protect chondrocytes from mechanically induced cartilage injury

Journal article

Kaneva, M., Kerrigan, M.J.P., Grieco, P., Curley, G.P., Locke, I.C. and Getting, S.J. 2014. Melanocortin peptides protect chondrocytes from mechanically induced cartilage injury. Biochemical Pharmacology. 92 (2), pp. 336-347. https://doi.org/10.1016/j.bcp.2014.08.019

O067 STARS SiRNA knockdown altered cardiac hypertrophy associated gene expression in cardiac myoblasts and rendered cells susceptible to hydrogen peroxide induced cell death

Article

Fothergill, D.P. and Chong, Nelson W. 2014. O067 STARS SiRNA knockdown altered cardiac hypertrophy associated gene expression in cardiac myoblasts and rendered cells susceptible to hydrogen peroxide induced cell death. Global Heart. 9 (1 Supp), pp. e18-e18. https://doi.org/10.1016/j.gheart.2014.03.1281

FRA2 is a STAT5 target gene regulated by IL-2 in human CD4 T cells

Article

Rani, A., Greenlaw, R., Runglall, M., Jurcevic, S. and John, S. 2014. FRA2 is a STAT5 target gene regulated by IL-2 in human CD4 T cells. PLoS ONE. 9 (2), p. e90370. https://doi.org/10.1371/journal.pone.0090370

A phase 1 study of prasugrel in patients with sickle cell disease: effects on biomarkers of platelet activation and coagulation

Article

Jakubowski, J.A., Zhou, C., Jurcevic, S., Winters, K.J., Lachno, D.R., Frelinger, A.L., Gupta, N., Howard, J., Payne, C.D. and Mant, T. 2014. A phase 1 study of prasugrel in patients with sickle cell disease: effects on biomarkers of platelet activation and coagulation. Thrombosis Research. 133 (2), pp. 190-5. https://doi.org/10.1016/j.thromres.2013.12.008

Telaprevir or boceprevir based therapy for chronic hepatitis C infection: Development of resistance-associated variants in treatment failure

Article

Macartney, M.J., Irish, D., Bridge, S.H., Garcia-Diaz, A., Booth, C., McCormick, A.L., Labbett, W., Smith, C., Velazquez, C., Tanwar, S., Trembling, P., Jacobs, M., Dusheiko, G., Rosenberg, W.M. and Haque, T. 2014. Telaprevir or boceprevir based therapy for chronic hepatitis C infection: Development of resistance-associated variants in treatment failure. Antiviral Research. 105, pp. 112-7. https://doi.org/10.1016/j.antiviral.2014.02.019

Prevalence of baseline polymorphisms for potential resistance to NS5A inhibitors in drug-naive individuals infected with hepatitis C genotypes 1–4

Article

McCormick, A.L., Wang, L., Garcia-Diaz, A., Macartney, M.J., Webster, D.P. and Haque, T. 2014. Prevalence of baseline polymorphisms for potential resistance to NS5A inhibitors in drug-naive individuals infected with hepatitis C genotypes 1–4 . Antiviral Therapy. 20 (1), pp. 81-85. https://doi.org/10.3851/IMP2763

The utility of different bioinformatics algorithms for genotypic HIV-1 tropism testing in a large clinical cohort with multiple subtypes

Journal article

Bartlett, A., Macartney, M.J., Conibear, T., Feyertag, F., Smith, C., Johnson, M., Hyams, C., Garcia-Diaz, A., McCormick, A.L., Booth, C., Robertson, D. and Webster, D.P. 2014. The utility of different bioinformatics algorithms for genotypic HIV-1 tropism testing in a large clinical cohort with multiple subtypes. AIDS. 28 (11), pp. 1611-7. https://doi.org/10.1097/QAD.0000000000000288

Baseline drug-resistance mutations are detectable in HCV genes NS3 and NS5A but not NS5B in acute and chronic HIV-coinfected patients

Journal article

McCormick, A.L., Moynihan, L., Macartney, M.J., Garcia-Diaz, A., Smith, C., Johnson, M., Rodger, A.J., Bhagani, S., Haque, T. and Webster, D. 2014. Baseline drug-resistance mutations are detectable in HCV genes NS3 and NS5A but not NS5B in acute and chronic HIV-coinfected patients. Antiviral Therapy. 20 (3), p. 2015. https://doi.org/10.3851/IMP2871

Hand drying method and risk of microbe dissemination: methods and benchmarks

Conference keynote

Redway, K. and Kimmitt, P.T. 2014. Hand drying method and risk of microbe dissemination: methods and benchmarks. Hospital Infection Society. Lyon, France 18 Nov 2014

Differing methodologies to measure microbe dispersal during hand drying

Conference poster

Redway, K. and Kimmitt, P.T. 2014. Differing methodologies to measure microbe dispersal during hand drying. Hospital Infection Society. Lyon, France 17 Nov 2014

Fibroblastic growth factor receptor 1 amplification in osteosarcoma is associated with poor response to neo-adjuvant chemotherapy

Journal article

Fernanda Amary, M., Ye, H., Berisha, F., Khatri, B., Forbes, G., Lehovsky, K., Frezza, A.M., Behjati, S., Tarpey, P., Pillay, N., Campbell, P.J., Tirabosco, R., Presneau, Nadège, Strauss, S.J. and Flanagan, A.M. 2014. Fibroblastic growth factor receptor 1 amplification in osteosarcoma is associated with poor response to neo-adjuvant chemotherapy. Cancer Medicine. 3 (4), pp. 980-987. https://doi.org/10.1002/cam4.268

Assessment of patient-derived tumour xenografts (PDXs) as a discovery tool for cancer epigenomics

Article

Guilhamon, P., Butcher, L.M., Presneau, Nadège, Wilson, G.A., Feber, A., Paul, D.S., Schütte, M., Haybaeck, J., Keilholz, U., Hoffman, J., Ross, M.T., Flanagan, A.M. and Beck, S. 2014. Assessment of patient-derived tumour xenografts (PDXs) as a discovery tool for cancer epigenomics. Genome Medicine. 6 (12), pp. 116-126. https://doi.org/10.1186/s13073-014-0116-0

A global phylogenetic analysis in order to determine the host species and geography dependent features present in the evolution of avian H9N2 influenza hemagglutinin

Article

Dalby, A.R. and Iqbal, M. 2014. A global phylogenetic analysis in order to determine the host species and geography dependent features present in the evolution of avian H9N2 influenza hemagglutinin. PeerJ. 2 e655. https://doi.org/10.7717/peerj.655

The Robustness of Pathway Analysis in Identifying Potential Drug Targets in Non-Small Cell Lung Carcinoma

Article

Dalby, A.R. and Bailey, I. 2014. The Robustness of Pathway Analysis in Identifying Potential Drug Targets in Non-Small Cell Lung Carcinoma. Microarrays. 3 (4), pp. 212-225. https://doi.org/10.3390/microarrays3040212

Detailed phenotypic and genotypic characterization of bietti crystalline dystrophy

Article

Halford, S., Liew, G., Mackay, D.S., Sergouniotis, P.I., Holt, R., Broadgate, S., Volpi, E., Ocaka, L., Robson, A.G., Holder, G.E., Moore, A.T., Michaelides, M. and Webster, A.R. 2014. Detailed phenotypic and genotypic characterization of bietti crystalline dystrophy. Ophtalmology. 121 (6), pp. 1174-1184. https://doi.org/10.1016/j.ophtha.2013.11.042

De novo and rare inherited mutations implicate the transcriptional coregulator TCF20/SPBP in autism spectrum disorder

Journal article

Babbs, C., Lloyd, D., Pagnamenta, A.T., Twiggs, S.R., Green, J., McGowan, S.J., Mirza, G., Naples, R., Sharma, V.P., Volpi, E., Buckle, V.J., Wall, S.A., Knight SJ; International Molecular Genetic Study of Autism Consortium (IMGSAC), Parr, J.R. and Wilkie, A.O. 2014. De novo and rare inherited mutations implicate the transcriptional coregulator TCF20/SPBP in autism spectrum disorder. Journal of Medical Genetics. 51 (11), pp. 737-747. https://doi.org/10.1136/jmedgenet-2014-102582

Post-Transcriptional Regulation of BCL2 mRNA by the RNA-Binding Protein ZFP36L1 in Malignant B Cells

Journal article

Zekavati, A., Nasir, A., Alcaraz, A., Aldrovandi, M., Marsh, P., Norton, J.D. and Murphy, J.J. 2014. Post-Transcriptional Regulation of BCL2 mRNA by the RNA-Binding Protein ZFP36L1 in Malignant B Cells. PLoS ONE. 9 (7) e102625. https://doi.org/10.1371/journal.pone.0102625

‘I just went with hope, because I thought I’m doing something’: Women’s Experiences of Western Herbal Practice for Distress

Conference poster

Yates, A., Whitehouse, J., Ridge, Damien T. and Green, J. 2014. ‘I just went with hope, because I thought I’m doing something’: Women’s Experiences of Western Herbal Practice for Distress. College of Medicine Multi-Disciplinary Student Summer School. King's College School of Nursing and Midwifery 05 Sep 2014

How women experience distress, and western herbal practice for the treatment of distress: implications for health care and self-management approaches

Conference paper

Yates, A., Whitehouse, J., Ridge, Damien T. and Green, J. 2014. How women experience distress, and western herbal practice for the treatment of distress: implications for health care and self-management approaches. University of Westminster Post-Graduate Fair. Univeristy of Westminster 29 Apr 2014

“It felt like someone holding you up and lifting the pain away”: Women's experiences of western herbal practice for the treatment of distress

Journal article

Yates, A.J., Green, J., Whitehouse, J. and Ridge, Damien T. 2014. “It felt like someone holding you up and lifting the pain away”: Women's experiences of western herbal practice for the treatment of distress. European Journal of Integrative Medicine. 6 (5), p. 612. https://doi.org/10.1016/j.eujim.2014.07.007

Buttressing volatile desktop grids with cloud resources within a reconfigurable environment service for workflow orchestration

Journal article

Winter, S., Reynolds, C.J., Kiss, T., Terstyanszky, G., Greenwell, P., McEldowney, S., Acs, S. and Kacsuk, P. 2014. Buttressing volatile desktop grids with cloud resources within a reconfigurable environment service for workflow orchestration. Journal of Cloud Computing: Advances, Systems and Applications. 3 (1), p. 1. https://doi.org/10.1186/2192-113X-3-1

A reflection on writing case records: development and current demands for acupuncture practitioners

Article

Wilson, J. 2014. A reflection on writing case records: development and current demands for acupuncture practitioners. TANG Humanitas Medicine. 4 (2), pp. 13.1-13.6. https://doi.org/10.5667/tang.2014.0012


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