Life Sciences

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Tailored food recipes-TFR: employing the European perspective

Journal article

Amlogu, A., Godden, K., Tewfik, S., Wambebe, C. and Tewfik, I. 2012. Tailored food recipes-TFR: employing the European perspective. International Journal of Food, Nutrition and Public Health. 5 (1/2/3), pp. 3-18.

Can adult neural stem cells create new brains? Plasticity in the adult mammalian neurogenic niches: realities and expectations in the era of regenerative biology

Journal article

Kazanis, I. 2012. Can adult neural stem cells create new brains? Plasticity in the adult mammalian neurogenic niches: realities and expectations in the era of regenerative biology. The Neuroscientist. 18 (1), pp. 15-27. https://doi.org/10.1177/1073858410390379

Individuals with moderately raised liver fat show a greater increase in liver fat in response to a high sugar diet

Article

Ahmad, A., Isherwood, C., Fielding, B.A., Bell, J.D., Thomas, E.L., Frost, G., Shojaee-Moradie, F., Umpleby, M. and Griffin, B.A. 2012. Individuals with moderately raised liver fat show a greater increase in liver fat in response to a high sugar diet. Proceedings of the Nutrition Society. 71 (Issue OCE2: Summer Meeting hosted by the Irish Section, 16–19 July 2012, Translational nutrition: integrating research, practice and policy) E31. https://doi.org/10.1017/s0029665112000882

Immunogenicity of a universal HIV-1 vaccine vectored by DNA, MVA and CHADV-63 in a Phase I/IIA clinical trial

Conference poster

Borthwick, N.J., Ahmed, T., Rose, A., Ebrahimsa, U., Black, A., Hayton, E., Yang, H., Hancock, G., Campion, S., Frahm, N., S Colloca, S., A Nicosia, A., A McMichael, A., L Dorrell, L. and Hanke, T. 2012. Immunogenicity of a universal HIV-1 vaccine vectored by DNA, MVA and CHADV-63 in a Phase I/IIA clinical trial. AIDS Vaccine 2012. Boston, MA, USA 09 - 12 Sep 2012 Springer. https://doi.org/10.1186/1742-4690-9-S2-P118

Prevalence and type of monoclonal gammopathy of undetermined significance in an apparently healthy Nigerian population: a cross sectional study

Journal article

Onwah, A Lawretta, Adeyemo, Titilope A, Adediran, Adewumi, John-olabode, Sarah and Akanmu, Alani S 2012. Prevalence and type of monoclonal gammopathy of undetermined significance in an apparently healthy Nigerian population: a cross sectional study. BMC Blood Disorders. 12 7. https://doi.org/10.1186/1471-2326-12-7

CD4 Count Pattern and Demographic Distribution of Treatment-Naïve HIV Patients in Lagos, Nigeria

Journal article

Akinbami, Akinsegun, Dosunmu, Adedoyin, Adediran, Adewumi and John-olabode, Sarah 2012. CD4 Count Pattern and Demographic Distribution of Treatment-Naïve HIV Patients in Lagos, Nigeria. AIDS Research and Treatment. Volume 2012 352753. https://doi.org/10.1155/2012/352753

Antibody combination therapy targeting CD25, CD70 and CD8 reduces islet inflammation and improves glycaemia in diabetic mice

Journal article

Alkhamis, T., Barbic, J., Crnogorac-Jurcevic, T., Greenlaw, R.E., Peakman, M. and Jurcevic, S. 2012. Antibody combination therapy targeting CD25, CD70 and CD8 reduces islet inflammation and improves glycaemia in diabetic mice. Clinical & Experimental Immunology. 170 (2), p. 139–148 PMC3482360. https://doi.org/10.1111/j.1365-2249.2012.04651.x

Age-stratified seroprevalence of vaccine-preventable infectious disease in Saravan, Southern Lao People’s Democratic Republic

Journal article

Xaydalasouk, Kinnaly, Sayasinh, Kong, Hübschen, Judith M, Khounvisith, Vilaysone, Keomany, Sommai, Muller, Claude P and Black, A. 2012. Age-stratified seroprevalence of vaccine-preventable infectious disease in Saravan, Southern Lao People’s Democratic Republic. International Journal of Infectious Diseases. 107, pp. 25-30. https://doi.org/10.1016/j.ijid.2021.04.033

Recombinant DNA/MVA/ChAdV-63-elicited T cells specific for conserved regions of the HIV-1 proteome recognize HIV-1 infected cells and suppress HIV-1

Journal article

Ahmed, T., Borthwick, N., Yang, H., Hancock, G., Yorke, L., Ebrahimsa, U., Rose, A., Black, A., Hayton, E., McMichael, A., Dorrell, L. and Hanke, T. 2012. Recombinant DNA/MVA/ChAdV-63-elicited T cells specific for conserved regions of the HIV-1 proteome recognize HIV-1 infected cells and suppress HIV-1. Retrovirology. 9, p. P259. https://doi.org/10.1186/1742-4690-9-S2-P259

Sphingolipid synthesis and scavenging in the intracellular apicomplexan parasite, Toxoplasma gondii

Journal article

Steven Pratt, Nilu Wansadhipathi-Kannangara, Catherine Bruce, John Mina, Hosam Shams-Eldin, Josefina Casas, Kentaro Hanada, Ralph T. Schwarz, Sabrina Sonda and Paul Denny 2012. Sphingolipid synthesis and scavenging in the intracellular apicomplexan parasite, Toxoplasma gondii. Molecular and Biochemical Parasitology. 187 (1), pp. 43-51. https://doi.org/10.1016/j.molbiopara.2012.11.007

Pregnancy associated plasma protein-A (PAPP-A) as an early marker for the diagnosis of acute coronary syndrome.

Journal article

Gururajan, P., Gurumurthy, P., Nayar, P., Rao, G.S., Babu, R.S., Sarasabharati, A. and Cherian, K.M. 2012. Pregnancy associated plasma protein-A (PAPP-A) as an early marker for the diagnosis of acute coronary syndrome. Indian Heart Journal. 64 (2), pp. 141-145. https://doi.org/10.1016/s0019-4832(12)60049-2

A novel calmodulin-like protein from the liver fluke, Fasciola hepatica

Journal article

Russell, Sean L., McFerran, Neil V., Moore, Catherine M., Tsang, Yvonne, Glass, Peter, Hoey, Elizabeth M., Trudgett, Alan and Timson, David J. 2012. A novel calmodulin-like protein from the liver fluke, Fasciola hepatica. Biochimie . 94 (11), pp. 2398-2406. https://doi.org/10.1016/j.biochi.2012.06.015

A plasma membrane Ca(2+)-ATPase (PMCA) from the liver fluke, Fasciola hepatica

Journal article

Moore, Catherine M., Hoey, Elizabeth M., Trudgett, Alan and Timson, David J. 2012. A plasma membrane Ca(2+)-ATPase (PMCA) from the liver fluke, Fasciola hepatica. International Journal for Parasitology. 42 (9), pp. 851-858. https://doi.org/10.1016/j.ijpara.2012.06.003

Loss of Rb Cooperates with Ras to Drive Oncogenic Growth in Mammalian Cells

Journal article

Melissa J. Collins, Ilaria Napoli, Sara Ribeiro, Sinead Roberts and Alison C. Lloyd 2012. Loss of Rb Cooperates with Ras to Drive Oncogenic Growth in Mammalian Cells. Current Biology. 22 (19), pp. 1765-1773. https://doi.org/10.1016/j.cub.2012.07.040

Measuring Synthesis and Degradation of MHC Class I Molecules

Book chapter

Guiliano, D.B. and Antoniou, A.N. 2012. Measuring Synthesis and Degradation of MHC Class I Molecules. in: van Endert, P. (ed.) Antigen Processing Springer. pp. 93-108

The MHC Class I Heavy Chain Structurally Conserved Cysteines 101 and 164 Participate in HLA-B27 Dimer Formation

Journal article

Lenart, I., Guiliano, D.B., Burn, G., Campbell, E.C., Morley, K.D., Fussell, H., Powis, S.J. and Antoniou, A.N. 2012. The MHC Class I Heavy Chain Structurally Conserved Cysteines 101 and 164 Participate in HLA-B27 Dimer Formation. Antioxidants and Redox Signaling. 16 (1), pp. 33-43. https://doi.org/10.1089/ars.2010.3693

Antigen Processing and Presentation by MHC Class I, II, and Nonclassical Molecules

Book chapter

Antoniou, A.N., Lenart, I., Guiliano, D.B. and Powis, S.J. 2012. Antigen Processing and Presentation by MHC Class I, II, and Nonclassical Molecules. in: Morrow, W.J.W., Sheikh, N.A., Schmidt, C.S. and Davies, D.H. (ed.) Vaccinology: Principles and Practice Wiley.

Introduction to helminth infections

Book chapter

Guiliano, D. 2012. Introduction to helminth infections. in: Lamb, T.J. (ed.) Immunity to Parasitic Infections Wiley-Blackwell.

Introduction to protozoan infections

Book chapter

Guiliano, D.B. and Lamb, T.J. 2012. Introduction to protozoan infections. in: Lamb, T.J. (ed.) Immunity to Parasitic Infections Wiley-Blackwell.

Neuropathology of 16p13.11 deletion in epilepsy

Journal article

Liu, J.Y.W., Kasperavičiute, D., Martinian, L., Thom, M. and Sisodiya, S.M. 2012. Neuropathology of 16p13.11 deletion in epilepsy. PLoS ONE. 7 (4). https://doi.org/10.1371/journal.pone.0034813

Neuropathology of the blood-brain barrier and pharmaco-resistance in human epilepsy

Article

Liu, J.Y.W., Thom, M., Catarino, C.B., Martinian, L., Figarella-Branger, D., Bartolomei, F., Koepp, M. and Sisodiya, S.M. 2012. Neuropathology of the blood-brain barrier and pharmaco-resistance in human epilepsy. Brain. 135 (10), p. 3115–3133. https://doi.org/10.1093/brain/aws147

Investigation of hypoxia-inducible factor-1α in hippocampal sclerosis: A postmortem study

Journal article

Feast, A., Martinian, L., Liu, J.Y.W., Catarino, C.B., Thom, M. and Sisodiya, S.M. 2012. Investigation of hypoxia-inducible factor-1α in hippocampal sclerosis: A postmortem study. Epilepsia. 53 (8), pp. 1349-1359. https://doi.org/10.1111/j.1528-1167.2012.03591.x

Variability of sclerosis along the longitudinal hippocampal axis in epilepsy: A post mortem study

Journal article

Thom, M., Liagkouras, I., Martinian, L., Catarino, C.B., Sisodiya, S.M. and Liu, J.Y.W. 2012. Variability of sclerosis along the longitudinal hippocampal axis in epilepsy: A post mortem study. Epilepsy Research. 102 (1-2), pp. 45-59. https://doi.org/10.1016/j.eplepsyres.2012.04.015

BEaST: brain extraction based on nonlocal segmentation technique.

Journal article

Eskildsen, S.F., Coupé, P., Fonov, V., Manjón, J.V., Leung, K.K., Guizard, N., Wassef, S.N., Østergaard, L.R., Collins, D.L., Alzheimer's Disease Neuroimaging Initiative and Whitcher, B. 2012. BEaST: brain extraction based on nonlocal segmentation technique. NeuroImage. 59 (3), pp. 2362-2373. https://doi.org/10.1016/j.neuroimage.2011.09.012

Individual subject classification for Alzheimer's disease based on incremental learning using a spatial frequency representation of cortical thickness data.

Journal article

Cho, Y., Seong, J.K., Jeong, Y., Shin, S.Y., Alzheimer's Disease Neuroimaging Initiative and Whitcher, B. 2012. Individual subject classification for Alzheimer's disease based on incremental learning using a spatial frequency representation of cortical thickness data. NeuroImage. 59 (3), pp. 2217-2230. https://doi.org/10.1016/j.neuroimage.2011.09.085

Detecting global and local hippocampal shape changes in Alzheimer's disease using statistical shape models.

Journal article

Shen, K.K., Fripp, J., Mériaudeau, F., Chételat,G., Salvado, O., Bourgeat, P., Alzheimer's Disease Neuroimaging Initiative and Whitcher, B. 2012. Detecting global and local hippocampal shape changes in Alzheimer's disease using statistical shape models. NeuroImage. 59 (3), pp. 2155-2166. https://doi.org/10.1016/j.neuroimage.2011.10.014

Localized hippocampus measures are associated with Alzheimer pathology and cognition independent of total hippocampal volume.

Journal article

Carmichael, O., Xie, J., Fletcher, E., Singh, B., DeCarli, C., Alzheimer's Disease Neuroimaging Initiative and Whitcher, B. 2012. Localized hippocampus measures are associated with Alzheimer pathology and cognition independent of total hippocampal volume. Neurobiology of Aging. 33 (6), pp. 1124.e31-1124.e41. https://doi.org/10.1016/j.neurobiolaging.2011.08.016

Imaging vascular function for early stage clinical trials using dynamic contrast-enhanced magnetic resonance imaging

Journal article

Leach, M.O., Morgan, B., Tofts, P.S., Buckley, D.L., Huang, W., Horsfield, M.A., Chenevert, T.L., Collins, D.J., Jackson, A., Lomas, D., Whitcher, B., Clarke, L., Plummer, R., Judson, I., Jones, R., Alonzi, R., Brunner, T., Koh, D.M., Murphy, P., Waterton, J.C., Parker, G., Graves, M.J., Scheenen, T.W.J., Redpath, T.W., Orton, M., Karczmar, G., Huisman, H., Barentsz, J. and Padhani, A. 2012. Imaging vascular function for early stage clinical trials using dynamic contrast-enhanced magnetic resonance imaging. European Radiology. 22, pp. 1451-1464. https://doi.org/10.1007/s00330-012-2446-x

A Comparison of Gray Matter Density in Restless Legs Syndrome Patients and Matched Controls Using Voxel-Based Morphometry

Journal article

Comley, R.A., Cervenka, S., Palhagen, S.E., Panagiotidis, G., Matthews, J.C., Lai, R.Y., Halldin, C., Farde, L., Nichols, T.E. and Whitcher, B. 2012. A Comparison of Gray Matter Density in Restless Legs Syndrome Patients and Matched Controls Using Voxel-Based Morphometry. Journal of Neuroimaging. 22 (1), pp. 28-32. https://doi.org/10.1111/j.1552-6569.2010.00536.x

Verbal working memory and functional large-scale networks in schizophrenia

Journal article

Dauvermann, M.R., Moorhead, T.W., Watson, A.R., Duff, B., Romaniuk, L., Hall, J., Roberts, N., Lee, G.L., Hughes, Z.A., Brandon, N.J., Whitcher, B., Blackwood, D.H., McIntosh, A.M. and Lawrie, S.M. 2012. Verbal working memory and functional large-scale networks in schizophrenia. Psychiatry Research: Neuroimaging. 270, pp. 86-96. https://doi.org/10.1016/j.pscychresns.2017.10.004

Using CSF biomarkers to replicate genetic associations in Alzheimer's disease.

Journal article

Schott, J.M., ADNI Investigators and Whitcher, B. 2012. Using CSF biomarkers to replicate genetic associations in Alzheimer's disease. Neurobiology of Aging. 33 (7), pp. 1486.e9-1486.e15. https://doi.org/10.1016/j.neurobiolaging.2011.02.008

Post-Synapse Model Cell for Synaptic Glutamate Receptor (GluR)-Based Biosensing: Strategy and Engineering to Maximize Ligand-Gated Ion-Flux Achieving High Signal-to-Noise Ratio

Journal article

Akito Tateishi, Sarah K. Coleman, Satoshi Migita, Kari Keinänen and Tetsuya Haruyama 2012. Post-Synapse Model Cell for Synaptic Glutamate Receptor (GluR)-Based Biosensing: Strategy and Engineering to Maximize Ligand-Gated Ion-Flux Achieving High Signal-to-Noise Ratio. Sensors. 12 (1), pp. 1035-1041. https://doi.org/10.3390/s120101035

Autoinactivation of the stargazin-AMPA receptor complex: subunit-dependency and independence from physical dissociation.

Journal article

Semenov, A., Möykkynen, T., Coleman, S.K., Korpi, E.R. and Keinänen, K. 2012. Autoinactivation of the stargazin-AMPA receptor complex: subunit-dependency and independence from physical dissociation. PLoS ONE. 7 (11) e49282. https://doi.org/10.1371/journal.pone.0049282

TpPred: A Tool for Hierarchical Prediction of Transport Proteins Using Cluster of Neural Networks and Sequence Derived Features

Journal article

Jain, S., Ranjan, P., Sengupta, D. and Naik, P.K. 2012. TpPred: A Tool for Hierarchical Prediction of Transport Proteins Using Cluster of Neural Networks and Sequence Derived Features. International Journal for Computational Biology. 1 (1), pp. 28-36.

A genome blogger manifesto

Journal article

Corpas, M. 2012. A genome blogger manifesto. GigaScience. 1 (1) 15. https://doi.org/10.1186/2047-217x-1-15

A family experience of personal genomics

Article

Corpas, M. 2012. A family experience of personal genomics. Journal of Genetic Counseling. 21 (3), pp. 386-391. https://doi.org/10.1007/s10897-011-9473-7

How not to be a bioinformatician

Journal article

Corpas, M., Fatumo, S. and Schneider, R. 2012. How not to be a bioinformatician. Source Code for Biology and Medicine. 7 3. https://doi.org/10.1186/1751-0473-7-3

DECIPHER: web-based, community resource for clinical interpretation of rare variants in developmental disorders.

Journal article

Swaminathan, G.J., Bragin, E., Chatzimichali, E.A., Corpas, M., Bevan, A.P., Wright, C.F., Carter, N.P., Hurles, M.E. and Firth, H.V. 2012. DECIPHER: web-based, community resource for clinical interpretation of rare variants in developmental disorders. Human Molecular Genetics. 21 (R1), pp. R37-R44. https://doi.org/10.1093/hmg/dds362

Interpretation of genomic copy number variants using DECIPHER

Journal article

Corpas, M., Bragin, E., Clayton, S., Bevan, P. and Firth, H.V. 2012. Interpretation of genomic copy number variants using DECIPHER. Current Protocols in Human Genetics. Chapter 8:Unit 8.14. https://doi.org/10.1002/0471142905.hg0814s72

Spanish cuts: more economic damage.

Article

Corpas, M. 2012. Spanish cuts: more economic damage. Nature. 487 38. https://doi.org/10.1038/487038d


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